PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2xwlB_

Fold library id	PDB Header	Molecule	Title
c2xwlB_	PDB header: transferase	Chain: B: PDB Molecule: 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase;	PDBTitle: crystal structure of ispd from mycobacterium smegmatis in complex2 with ctp and mg

Links to external resources
Added to library: Sat Apr 30 09:03:19 2011

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence A T V A V V P A A G S G E R L R A G R P K A F V T L G G T P L L E H A L S G L R A S G V I D R I V I A V P P A L T D E S K L V F G G E D S V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T S S S
G G G S T T T S
G G G
B T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence I V S G G V D R T E S V A L A L E A A G D A E F V L V H D A A R A L T P P A L I A R V V A A L K E G H S A V V P G L A P A D T I K A V D A N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S T T S
S
S
T T
T T
T
S
S S
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence G A V L G T P E R A G L R A V Q T P Q G F H A D V L R R A Y A R A T A G G V T D D A S L V E Q L G T P V Q I V D G D P L A F K I T T P L D L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
G G G
S
T T
S S S
T T T
G G G
S

. . . . . . . . . 220 . .

Sequence V L A E A V L A H H H H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	A	T	V	A	V	V	P	A	A	G	S	G	E	R	L	R	A	G	R	P	K	A	F	V	T	L	G	G	T	P	L	L	E	H	A	L	S	G	L	R	A	S	G	V	I	D	R	I	V	I	A	V	P	P	A	L	T	D	E	S	K	L	V	F	G	G	E	D	S	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													T	T	T	T	S	S	S		G	G	G	S			T	T														T	S											G	G	G										B	T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	I	V	S	G	G	V	D	R	T	E	S	V	A	L	A	L	E	A	A	G	D	A	E	F	V	L	V	H	D	A	A	R	A	L	T	P	P	A	L	I	A	R	V	V	A	A	L	K	E	G	H	S	A	V	V	P	G	L	A	P	A	D	T	I	K	A	V	D	A	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S	S										T	T	S		S		S							T	T		T	T																T		S									S	S							T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	G	A	V	L	G	T	P	E	R	A	G	L	R	A	V	Q	T	P	Q	G	F	H	A	D	V	L	R	R	A	Y	A	R	A	T	A	G	G	V	T	D	D	A	S	L	V	E	Q	L	G	T	P	V	Q	I	V	D	G	D	P	L	A	F	K	I	T	T	P	L	D	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S								G	G	G						S														T	T			S	S	S										T	T	T										G	G	G					S
	.	.	.	.	.	.	.	.	.	220	.	.
Sequence	V	L	A	E	A	V	L	A	H	H	H	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)