Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	Q	L	K	F	N	S	I	L	V	V	C	T	G	N	I	C	R	S	P	I	G	E	R	L	L	R	K	R	L	P	G	V	K	V	K	S	A	G	V	H	G	L	V	K	H	P	A	D	A	T	A	A	D	V	A	A	N	H
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																																							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	V	S	L	E	G	H	A	G	R	K	L	T	A	E	M	A	R	N	Y	D	L	I	L	A	M	E	S	E	H	I	A	Q	V	T	A	I	A	P	E	V	R	G	K	T	M	L	F	G	Q	W	L	E	Q	K	E	I	P	D	P
Secondary structure
SS confidence
Disorder										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.
Sequence		Y	R	K	S	Q	D	A	F	E	H	V	Y	G	M	L	E	R	A	S	Q	E	W	A	K	R	L	S	R
Secondary structure
SS confidence
Disorder																												?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2fek chain A Region: 6 - 148 Aligned: 143 Modelled: 143 Confidence: 100.0% Identity: 56% PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight protein-tyrosine- PDBTitle: structure of a protein tyrosine phosphatase Phyre2 PDB 2wmy chain H Region: 6 - 146 Aligned: 141 Modelled: 141 Confidence: 100.0% Identity: 62% PDB header:hydrolase Chain: H: PDB Molecule:putative acid phosphatase wzb; PDBTitle: crystal structure of the tyrosine phosphatase wzb from2 escherichia coli k30 in complex with sulphate. Phyre2 PDB 1dg9 chain A Region: 3 - 147 Aligned: 143 Modelled: 145 Confidence: 100.0% Identity: 32% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: Phosphotyrosine protein phosphatases I Family: Low-molecular-weight phosphotyrosine protein phosphatases Phyre2 PDB 2gi4 chain A Region: 6 - 148 Aligned: 141 Modelled: 143 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:possible phosphotyrosine protein phosphatase; PDBTitle: solution structure of the low molecular weight protein2 tyrosine phosphatase from campylobacter jejuni. Phyre2 PDB 5pnt chain A Region: 2 - 146 Aligned: 144 Modelled: 145 Confidence: 100.0% Identity: 32% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: Phosphotyrosine protein phosphatases I Family: Low-molecular-weight phosphotyrosine protein phosphatases Phyre2 PDB 2cwd chain A Region: 5 - 146 Aligned: 141 Modelled: 142 Confidence: 100.0% Identity: 39% PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight phosphotyrosine protein phosphatase; PDBTitle: crystal structure of tt1001 protein from thermus thermophilus hb8 Phyre2 PDB 1p8a chain A Region: 3 - 147 Aligned: 142 Modelled: 142 Confidence: 100.0% Identity: 23% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: Phosphotyrosine protein phosphatases I Family: Low-molecular-weight phosphotyrosine protein phosphatases Phyre2 PDB 1d1q chain A Region: 2 - 145 Aligned: 143 Modelled: 144 Confidence: 100.0% Identity: 27% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: Phosphotyrosine protein phosphatases I Family: Low-molecular-weight phosphotyrosine protein phosphatases Phyre2 PDB 3rof chain A Region: 5 - 148 Aligned: 140 Modelled: 142 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight protein-tyrosine-phosphatase ptpa; PDBTitle: crystal structure of the s. aureus protein tyrosine phosphatase ptpa Phyre2 PDB 1zgg chain A Region: 8 - 148 Aligned: 140 Modelled: 141 Confidence: 100.0% Identity: 31% PDB header:hydrolase Chain: A: PDB Molecule:putative low molecular weight protein-tyrosine- PDBTitle: solution structure of a low molecular weight protein2 tyrosine phosphatase from bacillus subtilis Phyre2 PDB 3jvi chain A Region: 8 - 148 Aligned: 138 Modelled: 141 Confidence: 100.0% Identity: 28% PDB header:hydrolase Chain: A: PDB Molecule:protein tyrosine phosphatase; PDBTitle: product state mimic crystal structure of protein tyrosine phosphatase2 from entamoeba histolytica Phyre2 PDB 1u2p chain A Region: 7 - 148 Aligned: 139 Modelled: 142 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight protein-tyrosine- PDBTitle: crystal structure of mycobacterium tuberculosis low2 molecular protein tyrosine phosphatase (mptpa) at 1.9a3 resolution Phyre2 PDB 2l18 chain A Region: 6 - 147 Aligned: 130 Modelled: 139 Confidence: 100.0% Identity: 20% PDB header:oxidoreductase Chain: A: PDB Molecule:arsenate reductase; PDBTitle: an arsenate reductase in the phosphate binding state Phyre2 PDB 1jf8 chain A Region: 6 - 145 Aligned: 128 Modelled: 140 Confidence: 100.0% Identity: 22% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: Phosphotyrosine protein phosphatases I Family: Low-molecular-weight phosphotyrosine protein phosphatases Phyre2 PDB 1jl3 chain A Region: 7 - 147 Aligned: 135 Modelled: 141 Confidence: 100.0% Identity: 20% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: Phosphotyrosine protein phosphatases I Family: Low-molecular-weight phosphotyrosine protein phosphatases Phyre2 PDB 1y1l chain A Region: 8 - 145 Aligned: 124 Modelled: 138 Confidence: 100.0% Identity: 23% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: Phosphotyrosine protein phosphatases I Family: Low-molecular-weight phosphotyrosine protein phosphatases Phyre2 PDB 3rh0 chain A Region: 6 - 143 Aligned: 125 Modelled: 138 Confidence: 100.0% Identity: 18% PDB header:oxidoreductase Chain: A: PDB Molecule:arsenate reductase; PDBTitle: corynebacterium glutamicum mycothiol/mycoredoxin1-dependent arsenate2 reductase cg_arsc2 Phyre2 PDB 3t38 chain B Region: 7 - 147 Aligned: 115 Modelled: 141 Confidence: 100.0% Identity: 23% PDB header:oxidoreductase Chain: B: PDB Molecule:arsenate reductase; PDBTitle: corynebacterium glutamicum thioredoxin-dependent arsenate reductase2 cg_arsc1' Phyre2 PDB 3fdf chain A Region: 8 - 148 Aligned: 135 Modelled: 140 Confidence: 97.3% Identity: 21% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:fr253; PDBTitle: crystal structure of the serine phosphatase of rna2 polymerase ii ctd (ssu72 superfamily) from drosophila3 melanogaster. orthorhombic crystal form. northeast4 structural genomics consortium target fr253. Phyre2 PDB 3o2q chain B Region: 8 - 96 Aligned: 85 Modelled: 89 Confidence: 96.9% Identity: 28% PDB header:hydrolase Chain: B: PDB Molecule:rna polymerase ii subunit a c-terminal domain phosphatase PDBTitle: crystal structure of the human symplekin-ssu72-ctd phosphopeptide2 complex Phyre2 1 c2fekA_ 2 c2wmyH_ 3 d1dg9a_ 4 c2gi4A_ 5 d5pnta_ 6 c2cwdA_ 7 d1p8aa_ 8 d1d1qa_ 9 c3rofA_ 10 c1zggA_ 11 c3jviA_ 12 c1u2pA_ 13 c2l18A_ 14 d1jf8a_ 15 d1jl3a_ 16 d1y1la_ 17 c3rh0A_ 18 c3t38B_ 19 c3fdfA_ 20 c3o2qB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2fekA_ 100.0 56 PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight protein-tyrosine- PDBTitle: structure of a protein tyrosine phosphatase 2 c2wmyH_ 100.0 62 PDB header:hydrolase Chain: H: PDB Molecule:putative acid phosphatase wzb; PDBTitle: crystal structure of the tyrosine phosphatase wzb from2 escherichia coli k30 in complex with sulphate. 3 d1dg9a_ 100.0 32 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 4 c2gi4A_ 100.0 23 PDB header:hydrolase Chain: A: PDB Molecule:possible phosphotyrosine protein phosphatase; PDBTitle: solution structure of the low molecular weight protein2 tyrosine phosphatase from campylobacter jejuni. 5 d5pnta_ 100.0 32 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 6 c2cwdA_ 100.0 39 PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight phosphotyrosine protein phosphatase; PDBTitle: crystal structure of tt1001 protein from thermus thermophilus hb8 7 d1p8aa_ 100.0 23 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 8 d1d1qa_ 100.0 27 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 9 c3rofA_ 100.0 27 PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight protein-tyrosine-phosphatase ptpa; PDBTitle: crystal structure of the s. aureus protein tyrosine phosphatase ptpa 10 c1zggA_ 100.0 31 PDB header:hydrolase Chain: A: PDB Molecule:putative low molecular weight protein-tyrosine- PDBTitle: solution structure of a low molecular weight protein2 tyrosine phosphatase from bacillus subtilis 11 c3jviA_ 100.0 28 PDB header:hydrolase Chain: A: PDB Molecule:protein tyrosine phosphatase; PDBTitle: product state mimic crystal structure of protein tyrosine phosphatase2 from entamoeba histolytica 12 c1u2pA_ 100.0 29 PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight protein-tyrosine- PDBTitle: crystal structure of mycobacterium tuberculosis low2 molecular protein tyrosine phosphatase (mptpa) at 1.9a3 resolution 13 c2l18A_ 100.0 20 PDB header:oxidoreductase Chain: A: PDB Molecule:arsenate reductase; PDBTitle: an arsenate reductase in the phosphate binding state 14 d1jf8a_ 100.0 22 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 15 d1jl3a_ 100.0 20 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 16 d1y1la_ 100.0 23 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 17 c3rh0A_ 100.0 18 PDB header:oxidoreductase Chain: A: PDB Molecule:arsenate reductase; PDBTitle: corynebacterium glutamicum mycothiol/mycoredoxin1-dependent arsenate2 reductase cg_arsc2 18 c3t38B_ 100.0 23 PDB header:oxidoreductase Chain: B: PDB Molecule:arsenate reductase; PDBTitle: corynebacterium glutamicum thioredoxin-dependent arsenate reductase2 cg_arsc1' 19 c3fdfA_ 97.3 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:fr253; PDBTitle: crystal structure of the serine phosphatase of rna2 polymerase ii ctd (ssu72 superfamily) from drosophila3 melanogaster. orthorhombic crystal form. northeast4 structural genomics consortium target fr253. 20 c3o2qB_ 96.9 28 PDB header:hydrolase Chain: B: PDB Molecule:rna polymerase ii subunit a c-terminal domain phosphatase PDBTitle: crystal structure of the human symplekin-ssu72-ctd phosphopeptide2 complex 21 c3o2sB_ not modelled 96.6 29 PDB header:hydrolase Chain: B: PDB Molecule:rna polymerase ii subunit a c-terminal domain phosphatase PDBTitle: crystal structure of the human symplekin-ssu72 complex 22 c2f00A_ not modelled 94.9 16 PDB header:ligase Chain: A: PDB Molecule:udp-n-acetylmuramate--l-alanine ligase; PDBTitle: escherichia coli murc 23 c1gpjA_ not modelled 90.1 18 PDB header:reductase Chain: A: PDB Molecule:glutamyl-trna reductase; PDBTitle: glutamyl-trna reductase from methanopyrus kandleri 24 d1p3da1 not modelled 89.0 19 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 25 c1j6uA_ not modelled 87.5 17 PDB header:ligase Chain: A: PDB Molecule:udp-n-acetylmuramate-alanine ligase murc; PDBTitle: crystal structure of udp-n-acetylmuramate-alanine ligase2 murc (tm0231) from thermotoga maritima at 2.3 a resolution 26 d1pjqa1 not modelled 86.6 18 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Siroheme synthase N-terminal domain-like 27 d1gpja2 not modelled 85.9 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain 28 d1j6ua1 not modelled 82.5 17 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 29 c1vkrA_ not modelled 81.0 30 PDB header:transferase Chain: A: PDB Molecule:mannitol-specific pts system enzyme iiabc components; PDBTitle: structure of iib domain of the mannitol-specific permease enzyme ii 30 d1vkra_ not modelled 81.0 30 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:PTS system IIB component-like Family:PTS system, Lactose/Cellobiose specific IIB subunit 31 c3ggpA_ not modelled 80.8 17 PDB header:oxidoreductase Chain: A: PDB Molecule:prephenate dehydrogenase; PDBTitle: crystal structure of prephenate dehydrogenase from a. aeolicus in2 complex with hydroxyphenyl propionate and nad+ 32 c1gqqA_ not modelled 80.0 20 PDB header:cell wall biosynthesis Chain: A: PDB Molecule:udp-n-acetylmuramate-l-alanine ligase; PDBTitle: murc - crystal structure of the apo-enzyme from haemophilus2 influenzae 33 c1ml4A_ not modelled 79.9 11 PDB header:transferase Chain: A: PDB Molecule:aspartate transcarbamoylase; PDBTitle: the pala-liganded aspartate transcarbamoylase catalytic subunit from2 pyrococcus abyssi 34 c2rgwD_ not modelled 79.6 12 PDB header:transferase Chain: D: PDB Molecule:aspartate carbamoyltransferase; PDBTitle: catalytic subunit of m. jannaschii aspartate2 transcarbamoylase 35 d1tuga1 not modelled 77.0 16 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 36 c3eagA_ not modelled 75.5 10 PDB header:ligase Chain: A: PDB Molecule:udp-n-acetylmuramate:l-alanyl-gamma-d-glutamyl-meso- PDBTitle: the crystal structure of udp-n-acetylmuramate:l-alanyl-gamma-d-2 glutamyl-meso-diaminopimelate ligase (mpl) from neisseria3 meningitides 37 c1tvmA_ not modelled 75.5 19 PDB header:transferase Chain: A: PDB Molecule:pts system, galactitol-specific iib component; PDBTitle: nmr structure of enzyme gatb of the galactitol-specific2 phosphoenolpyruvate-dependent phosphotransferase system 38 c3kcqA_ not modelled 75.3 21 PDB header:transferase Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase; PDBTitle: crystal structure of phosphoribosylglycinamide formyltransferase from2 anaplasma phagocytophilum 39 c3czcA_ not modelled 74.7 14 PDB header:transferase Chain: A: PDB Molecule:rmpb; PDBTitle: the crystal structure of a putative pts iib(ptxb) from2 streptococcus mutans 40 c2bibA_ not modelled 73.6 8 PDB header:hydrolase Chain: A: PDB Molecule:teichoic acid phosphorylcholine esterase/ choline binding PDBTitle: crystal structure of the complete modular teichioic acid2 phosphorylcholine esterase pce (cbpe) from streptococcus3 pneumoniae 41 d2jfga1 not modelled 72.2 20 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 42 d1vlva2 not modelled 71.5 13 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 43 c3ktdC_ not modelled 70.2 17 PDB header:oxidoreductase Chain: C: PDB Molecule:prephenate dehydrogenase; PDBTitle: crystal structure of a putative prephenate dehydrogenase (cgl0226)2 from corynebacterium glutamicum atcc 13032 at 2.60 a resolution 44 c3hn7A_ not modelled 69.6 16 PDB header:ligase Chain: A: PDB Molecule:udp-n-acetylmuramate-l-alanine ligase; PDBTitle: crystal structure of a murein peptide ligase mpl (psyc_0032) from2 psychrobacter arcticus 273-4 at 1.65 a resolution 45 c2eq8C_ not modelled 69.1 30 PDB header:oxidoreductase Chain: C: PDB Molecule:pyruvate dehydrogenase complex, dihydrolipoamide PDBTitle: crystal structure of lipoamide dehydrogenase from thermus thermophilus2 hb8 with psbdp 46 c3dfzB_ not modelled 68.2 20 PDB header:oxidoreductase Chain: B: PDB Molecule:precorrin-2 dehydrogenase; PDBTitle: sirc, precorrin-2 dehydrogenase 47 c3l6dB_ not modelled 64.4 16 PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of putative oxidoreductase from pseudomonas putida2 kt2440 48 d1u6ka1 not modelled 63.3 21 Fold:F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD) Superfamily:F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD) Family:F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD) 49 c3gt0A_ not modelled 59.8 17 PDB header:oxidoreductase Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase; PDBTitle: crystal structure of pyrroline 5-carboxylate reductase from bacillus2 cereus. northeast structural genomics consortium target bcr38b 50 c3b1fA_ not modelled 56.1 20 PDB header:oxidoreductase Chain: A: PDB Molecule:putative prephenate dehydrogenase; PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 mutans 51 d1cmca_ not modelled 54.6 13 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:Met repressor, MetJ (MetR) 52 c1wv9B_ not modelled 54.3 17 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:rhodanese homolog tt1651; PDBTitle: crystal structure of rhodanese homolog tt1651 from an2 extremely thermophilic bacterium thermus thermophilus hb8 53 d1jzta_ not modelled 52.9 14 Fold:YjeF N-terminal domain-like Superfamily:YjeF N-terminal domain-like Family:YjeF N-terminal domain-like 54 d1bala_ not modelled 51.8 17 Fold:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Superfamily:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Family:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 55 c3i2vA_ not modelled 51.8 19 PDB header:transferase Chain: A: PDB Molecule:adenylyltransferase and sulfurtransferase mocs3; PDBTitle: crystal structure of human mocs3 rhodanese-like domain 56 c1e0cA_ not modelled 51.0 20 PDB header:sulfurtransferase Chain: A: PDB Molecule:sulfurtransferase; PDBTitle: sulfurtransferase from azotobacter vinelandii 57 d1yt8a4 not modelled 50.1 13 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 58 d1w85i_ not modelled 50.0 19 Fold:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Superfamily:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Family:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 59 c3d1pA_ not modelled 49.6 11 PDB header:transferase Chain: A: PDB Molecule:putative thiosulfate sulfurtransferase yor285w; PDBTitle: atomic resolution structure of uncharacterized protein from2 saccharomyces cerevisiae 60 c2rhoB_ not modelled 48.4 22 PDB header:cell cycle Chain: B: PDB Molecule:cell division protein ftsz; PDBTitle: synthetic gene encoded bacillus subtilis ftsz ncs dimer with2 bound gdp and gtp-gamma-s 61 d1duvg2 not modelled 48.3 13 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 62 c2e85B_ not modelled 47.1 17 PDB header:hydrolase Chain: B: PDB Molecule:hydrogenase 3 maturation protease; PDBTitle: crystal structure of the hydrogenase 3 maturation protease 63 d1w4ha1 not modelled 46.6 17 Fold:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Superfamily:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Family:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 64 c2k0zA_ not modelled 46.3 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein hp1203; PDBTitle: solution nmr structure of protein hp1203 from helicobacter pylori2 26695. northeast structural genomics consortium (nesg) target3 pt1/ontario center for structural proteomics target hp1203 65 d1ml4a2 not modelled 45.5 8 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 66 c2eq9C_ not modelled 45.0 28 PDB header:oxidoreductase Chain: C: PDB Molecule:pyruvate dehydrogenase complex, dihydrolipoamide PDBTitle: crystal structure of lipoamide dehydrogenase from thermus thermophilus2 hb8 with psbdb 67 c3ghyA_ not modelled 44.4 18 PDB header:oxidoreductase Chain: A: PDB Molecule:ketopantoate reductase protein; PDBTitle: crystal structure of a putative ketopantoate reductase from ralstonia2 solanacearum molk2 68 c1np3B_ not modelled 43.7 13 PDB header:oxidoreductase Chain: B: PDB Molecule:ketol-acid reductoisomerase; PDBTitle: crystal structure of class i acetohydroxy acid isomeroreductase from2 pseudomonas aeruginosa 69 d2fug21 not modelled 43.6 25 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:NQO2-like 70 d2cyua1 not modelled 42.8 19 Fold:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Superfamily:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Family:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 71 c3lxmC_ not modelled 42.7 18 PDB header:transferase Chain: C: PDB Molecule:aspartate carbamoyltransferase; PDBTitle: 2.00 angstrom resolution crystal structure of a catalytic2 subunit of an aspartate carbamoyltransferase (pyrb) from3 yersinia pestis co92 72 c1zwvA_ not modelled 42.5 22 PDB header:transferase Chain: A: PDB Molecule:lipoamide acyltransferase component of branched- PDBTitle: solution structure of the subunit binding domain (hbsbd) of2 the human mitochondrial branched-chain alpha-ketoacid3 dehydrogenase 73 c1m67A_ not modelled 41.6 18 PDB header:oxidoreductase Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase; PDBTitle: crystal structure of leishmania mexicana gpdh complexed with inhibitor2 2-bromo-6-hydroxy-purine 74 c3ia7A_ not modelled 41.3 12 PDB header:transferase Chain: A: PDB Molecule:calg4; PDBTitle: crystal structure of calg4, the calicheamicin glycosyltransferase 75 d2vapa1 not modelled 40.7 18 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 76 d1u9ca_ not modelled 40.5 17 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:DJ-1/PfpI 77 c1w5fA_ not modelled 39.6 19 PDB header:cell division Chain: A: PDB Molecule:cell division protein ftsz; PDBTitle: ftsz, t7 mutated, domain swapped (t. maritima) 78 c1w3dA_ not modelled 39.4 19 PDB header:transferase Chain: A: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase PDBTitle: nmr structure of the peripheral-subunit binding domain of2 bacillus stearothermophilus e2p 79 c2jtqA_ not modelled 39.1 17 PDB header:transferase Chain: A: PDB Molecule:phage shock protein e; PDBTitle: rhodanese from e.coli 80 d1iiba_ not modelled 39.1 11 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:PTS system IIB component-like Family:PTS system, Lactose/Cellobiose specific IIB subunit 81 c3fojA_ not modelled 38.7 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of ssp1007 from staphylococcus2 saprophyticus subsp. saprophyticus. northeast structural3 genomics target syr101a. 82 c3emeA_ not modelled 38.6 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:rhodanese-like domain protein; PDBTitle: crystal structure of rhodanese-like domain protein from2 staphylococcus aureus 83 c2auvA_ not modelled 38.0 17 PDB header:oxidoreductase Chain: A: PDB Molecule:potential nad-reducing hydrogenase subunit; PDBTitle: solution structure of hndac : a thioredoxin-like [2fe-2s]2 ferredoxin involved in the nadp-reducing hydrogenase3 complex 84 c3k96B_ not modelled 37.9 18 PDB header:oxidoreductase Chain: B: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+]; PDBTitle: 2.1 angstrom resolution crystal structure of glycerol-3-phosphate2 dehydrogenase (gpsa) from coxiella burnetii 85 c2g5cD_ not modelled 37.3 17 PDB header:oxidoreductase Chain: D: PDB Molecule:prephenate dehydrogenase; PDBTitle: crystal structure of prephenate dehydrogenase from aquifex aeolicus 86 c1w4kA_ not modelled 37.1 22 PDB header:transferase Chain: A: PDB Molecule:pyruvate dehydrogenase e2; PDBTitle: peripheral-subunit binding domains from mesophilic,2 thermophilic, and hyperthermophilic bacteria fold by3 ultrafast, apparently two-state transitions 87 c2eq7C_ not modelled 36.8 22 PDB header:oxidoreductase Chain: C: PDB Molecule:2-oxoglutarate dehydrogenase e2 component; PDBTitle: crystal structure of lipoamide dehydrogenase from thermus thermophilus2 hb8 with psbdo 88 c2cooA_ not modelled 36.4 22 PDB header:transferase Chain: A: PDB Molecule:lipoamide acyltransferase component of branched- PDBTitle: solution structure of the e3_binding domain of2 dihydrolipoamide branched chaintransacylase 89 d1n1ea2 not modelled 36.2 23 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 90 c3nbmA_ not modelled 36.0 18 PDB header:transferase Chain: A: PDB Molecule:pts system, lactose-specific iibc components; PDBTitle: the lactose-specific iib component domain structure of the2 phosphoenolpyruvate:carbohydrate phosphotransferase system (pts) from3 streptococcus pneumoniae. 91 d1cfza_ not modelled 35.6 33 Fold:Phosphorylase/hydrolase-like Superfamily:HybD-like Family:Hydrogenase maturating endopeptidase HybD 92 d1f37b_ not modelled 35.5 13 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioredoxin-like 2Fe-2S ferredoxin 93 d1llca1 not modelled 34.8 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 94 c2imgA_ not modelled 34.6 19 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity protein phosphatase 23; PDBTitle: crystal structure of dual specificity protein phosphatase2 23 from homo sapiens in complex with ligand malate ion 95 c2g6zB_ not modelled 34.5 38 PDB header:hydrolase Chain: B: PDB Molecule:dual specificity protein phosphatase 5; PDBTitle: crystal structure of human dusp5 96 c3triB_ not modelled 33.9 20 PDB header:oxidoreductase Chain: B: PDB Molecule:pyrroline-5-carboxylate reductase; PDBTitle: structure of a pyrroline-5-carboxylate reductase (proc) from coxiella2 burnetii 97 d1ekxa2 not modelled 33.7 12 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 98 c3dv0I_ not modelled 33.5 23 PDB header:oxidoreductase/transferase Chain: I: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase PDBTitle: snapshots of catalysis in the e1 subunit of the pyruvate2 dehydrogenase multi-enzyme complex 99 d1w85b2 not modelled 33.4 9 Fold:TK C-terminal domain-like Superfamily:TK C-terminal domain-like Family:Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain 100 c2eg4B_ not modelled 32.8 21 PDB header:transferase Chain: B: PDB Molecule:probable thiosulfate sulfurtransferase; PDBTitle: crystal structure of probable thiosulfate sulfurtransferase 101 c1evjC_ not modelled 32.6 16 PDB header:oxidoreductase Chain: C: PDB Molecule:glucose-fructose oxidoreductase; PDBTitle: crystal structure of glucose-fructose oxidoreductase (gfor)2 delta1-22 s64d 102 d1wraa1 not modelled 32.1 7 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Pce catalytic domain-like 103 c3d0oA_ not modelled 32.1 12 PDB header:oxidoreductase Chain: A: PDB Molecule:l-lactate dehydrogenase 1; PDBTitle: crystal structure of lactate dehydrogenase from2 staphylococcus aureus 104 d1dxha2 not modelled 31.0 13 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 105 c2uzqE_ not modelled 30.7 23 PDB header:hydrolase Chain: E: PDB Molecule:m-phase inducer phosphatase 2; PDBTitle: protein phosphatase, new crystal form 106 c1i36A_ not modelled 30.6 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein mth1747; PDBTitle: structure of conserved protein mth1747 of unknown function2 reveals structural similarity with 3-hydroxyacid3 dehydrogenases 107 c1w59B_ not modelled 30.6 18 PDB header:cell division Chain: B: PDB Molecule:cell division protein ftsz homolog 1; PDBTitle: ftsz dimer, empty (m. jannaschii) 108 d1hdoa_ not modelled 30.6 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 109 d1umdb2 not modelled 30.4 16 Fold:TK C-terminal domain-like Superfamily:TK C-terminal domain-like Family:Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain 110 c1yz4A_ not modelled 30.4 29 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity phosphatase-like 15 isoform a; PDBTitle: crystal structure of dusp15 111 d1zh8a1 not modelled 29.6 14 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 112 c3rgqA_ not modelled 29.6 19 PDB header:hydrolase Chain: A: PDB Molecule:protein-tyrosine phosphatase mitochondrial 1; PDBTitle: crystal structure of ptpmt1 in complex with pi(5)p 113 c3g5jA_ not modelled 29.3 20 PDB header:nucleotide binding protein Chain: A: PDB Molecule:putative atp/gtp binding protein; PDBTitle: crystal structure of n-terminal domain of putative atp/gtp binding2 protein from clostridium difficile 630 114 c2vawA_ not modelled 29.3 22 PDB header:cell cycle Chain: A: PDB Molecule:cell division protein ftsz; PDBTitle: ftsz pseudomonas aeruginosa gdp 115 c1ofuB_ not modelled 28.7 22 PDB header:bacterial cell division inhibitor Chain: B: PDB Molecule:cell division protein ftsz; PDBTitle: crystal structure of sula:ftsz from pseudomonas aeruginosa 116 c3c1oA_ not modelled 28.6 15 PDB header:oxidoreductase Chain: A: PDB Molecule:eugenol synthase; PDBTitle: the multiple phenylpropene synthases in both clarkia2 breweri and petunia hybrida represent two distinct lineages 117 d1f0ya2 not modelled 28.6 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 118 c2wgpA_ not modelled 27.7 29 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity protein phosphatase 14; PDBTitle: crystal structure of human dual specificity phosphatase 14 119 d1okga2 not modelled 27.1 11 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 120 c3oj0A_ not modelled 27.0 19 PDB header:oxidoreductase Chain: A: PDB Molecule:glutamyl-trna reductase; PDBTitle: crystal structure of glutamyl-trna reductase from thermoplasma2 volcanium (nucleotide binding domain)

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0