Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	L	S	M	K	S	L	A	A	L	L	M	M	L	N	G	A	V	M	A	S	E	N	V	N	T	P	E	N	R	Q	F	L	K	Q	Q	E	N	L	S	R	Q	L	R	E	K	P	D	H	Q	L	K	A	W	A	E	K	Q	V
Secondary structure
SS confidence
Disorder		?	?	?												?	?	?	?	?	?	?	?	?	?	?	?	?		?	?																?	?	?								?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	E	N	P	L	Q	R	S	D	N	H	F	L	D	E	L	V	R	K	Q	Q	A	S	Q	D	G	K	P	R	Q	G	A	L	Y	F	V	S	F	S	I	P	E	E	G	L	K	R	M	L	G	E	T	R	H	F	G	I	P	A	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?										?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	R	G	M	V	N	N	D	L	K	T	T	A	E	A	V	L	S	L	V	K	D	G	A	T	D	G	V	Q	I	D	P	T	L	F	S	Q	Y	G	I	R	T	V	P	A	L	V	V	F	C	S	Q	G	Y	D	I	I	R	G	N
Secondary structure
SS confidence
Disorder																						?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.
Sequence		L	R	V	G	Q	A	L	E	K	V	A	A	T	G	D	C	R	Q	V	A	H	D	L	L	A	G	K	G	D	S	G	K
Secondary structure
SS confidence
Disorder														?	?	?	?											?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1hyu chain A domain 4 Region: 103 - 190 Aligned: 85 Modelled: 88 Confidence: 95.4% Identity: 13% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: PDI-like Phyre2 PDB 2vlv chain A Region: 102 - 193 Aligned: 91 Modelled: 92 Confidence: 95.2% Identity: 10% PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin h isoform 2.; PDBTitle: crystal structure of barley thioredoxin h isoform 2 in2 partially radiation-reduced state Phyre2 PDB 1j08 chain A domain 2 Region: 151 - 192 Aligned: 42 Modelled: 42 Confidence: 95.1% Identity: 24% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: PDI-like Phyre2 PDB 1a8l chain A domain 2 Region: 129 - 192 Aligned: 64 Modelled: 64 Confidence: 93.6% Identity: 17% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: PDI-like Phyre2 PDB 1j08 chain A Region: 129 - 192 Aligned: 64 Modelled: 64 Confidence: 92.9% Identity: 19% PDB header:isomerase Chain: A: PDB Molecule:glutaredoxin-like protein; PDBTitle: crystal structure of glutaredoxin-like protein from2 pyrococcus horikoshii Phyre2 PDB 3gnj chain D Region: 151 - 192 Aligned: 42 Modelled: 42 Confidence: 92.6% Identity: 19% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:thioredoxin domain protein; PDBTitle: the crystal structure of a thioredoxin-related protein from2 desulfitobacterium hafniense dcb Phyre2 PDB 1zyp chain B Region: 106 - 190 Aligned: 82 Modelled: 85 Confidence: 91.9% Identity: 15% PDB header:oxidoreductase Chain: B: PDB Molecule:alkyl hydroperoxide reductase subunit f; PDBTitle: synchrotron reduced form of the n-terminal domain of2 salmonella typhimurium ahpf Phyre2 PDB 3emx chain B Region: 151 - 192 Aligned: 42 Modelled: 42 Confidence: 91.8% Identity: 19% PDB header:oxidoreductase Chain: B: PDB Molecule:thioredoxin; PDBTitle: crystal structure of thioredoxin from aeropyrum pernix Phyre2 PDB 1dby chain A Region: 151 - 192 Aligned: 42 Modelled: 42 Confidence: 91.4% Identity: 29% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Thioltransferase Phyre2 PDB 2qsi chain B Region: 151 - 192 Aligned: 42 Modelled: 42 Confidence: 91.4% Identity: 19% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative hydrogenase expression/formation protein hupg; PDBTitle: crystal structure of putative hydrogenase expression/formation protein2 hupg from rhodopseudomonas palustris cga009 Phyre2 PDB 2voc chain A Region: 151 - 192 Aligned: 42 Modelled: 42 Confidence: 91.2% Identity: 19% PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: thioredoxin a active site mutants form mixed disulfide2 dimers that resemble enzyme-substrate reaction3 intermediate Phyre2 PDB 1t4z chain A Region: 115 - 182 Aligned: 67 Modelled: 68 Confidence: 91.0% Identity: 24% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: KaiB-like Phyre2 PDB 2ppt chain A Region: 151 - 192 Aligned: 42 Modelled: 42 Confidence: 90.6% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin-2; PDBTitle: crystal structure of thioredoxin-2 Phyre2 PDB 2e0q chain A Region: 151 - 192 Aligned: 42 Modelled: 42 Confidence: 90.2% Identity: 19% PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of k53e thioredoxin from sulfolobus2 tokodaii strain7 Phyre2 PDB 2dj2 chain A Region: 151 - 193 Aligned: 43 Modelled: 43 Confidence: 90.2% Identity: 12% PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a4; PDBTitle: the solution structure of the second thioredoxin domain of2 mouse protein disulfide-isomerase a4 Phyre2 PDB 3p2a chain B Region: 151 - 192 Aligned: 42 Modelled: 42 Confidence: 90.0% Identity: 17% PDB header:oxidoreductase Chain: B: PDB Molecule:putative thioredoxin-like protein; PDBTitle: crystal structure of thioredoxin 2 from yersinia pestis Phyre2 PDB 2i4a chain A Region: 151 - 192 Aligned: 42 Modelled: 42 Confidence: 89.9% Identity: 24% PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of thioredoxin from the acidophile2 acetobacter aceti Phyre2 PDB 3ul3 chain A Region: 151 - 193 Aligned: 43 Modelled: 43 Confidence: 89.8% Identity: 5% PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: structural insights into thioredoxin-2: a component of malaria2 parasite protein secretion machinery Phyre2 PDB 1ep7 chain A Region: 102 - 193 Aligned: 91 Modelled: 92 Confidence: 88.6% Identity: 13% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Thioltransferase Phyre2 PDB 1w89 chain E Region: 151 - 192 Aligned: 42 Modelled: 42 Confidence: 88.6% Identity: 17% PDB header:electron transport Chain: E: PDB Molecule:thioredoxin; PDBTitle: structure of the reduced form of human thioredoxin 2 Phyre2 PDB 2hfd chain A domain 1 Region: 151 - 211 Aligned: 51 Modelled: 51 Confidence: 88.5% Identity: 14% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: HyaE-like Phyre2 PDB 2dun chain A Region: 90 - 157 Aligned: 68 Modelled: 68 Confidence: 55.3% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:dna polymerase mu; PDBTitle: solution structure of brct domain of dna polymerase mu Phyre2 1 d1hyua4 2 c2vlvA_ 3 d1j08a2 4 d1a8la2 5 c1j08A_ 6 c3gnjD_ 7 c1zypB_ 8 c3emxB_ 9 d1dbya_ 10 c2qsiB_ 11 c2vocA_ 12 d1t4za_ 13 c2pptA_ 14 c2e0qA_ 15 c2dj2A_ 16 c3p2aB_ 17 c2i4aA_ 18 c3ul3A_ 19 d1ep7a_ 20 c1w89E_ 21 d2hfda1 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 c2dunA_ 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1hyua4 95.4 13 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 2 c2vlvA_ 95.2 10 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin h isoform 2.; PDBTitle: crystal structure of barley thioredoxin h isoform 2 in2 partially radiation-reduced state 3 d1j08a2 95.1 24 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 4 d1a8la2 93.6 17 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 5 c1j08A_ 92.9 19 PDB header:isomerase Chain: A: PDB Molecule:glutaredoxin-like protein; PDBTitle: crystal structure of glutaredoxin-like protein from2 pyrococcus horikoshii 6 c3gnjD_ 92.6 19 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:thioredoxin domain protein; PDBTitle: the crystal structure of a thioredoxin-related protein from2 desulfitobacterium hafniense dcb 7 c1zypB_ 91.9 15 PDB header:oxidoreductase Chain: B: PDB Molecule:alkyl hydroperoxide reductase subunit f; PDBTitle: synchrotron reduced form of the n-terminal domain of2 salmonella typhimurium ahpf 8 c3emxB_ 91.8 19 PDB header:oxidoreductase Chain: B: PDB Molecule:thioredoxin; PDBTitle: crystal structure of thioredoxin from aeropyrum pernix 9 d1dbya_ 91.4 29 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 10 c2qsiB_ 91.4 19 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative hydrogenase expression/formation protein hupg; PDBTitle: crystal structure of putative hydrogenase expression/formation protein2 hupg from rhodopseudomonas palustris cga009 11 c2vocA_ 91.2 19 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: thioredoxin a active site mutants form mixed disulfide2 dimers that resemble enzyme-substrate reaction3 intermediate 12 d1t4za_ 91.0 24 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:KaiB-like 13 c2pptA_ 90.6 17 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin-2; PDBTitle: crystal structure of thioredoxin-2 14 c2e0qA_ 90.2 19 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of k53e thioredoxin from sulfolobus2 tokodaii strain7 15 c2dj2A_ 90.2 12 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a4; PDBTitle: the solution structure of the second thioredoxin domain of2 mouse protein disulfide-isomerase a4 16 c3p2aB_ 90.0 17 PDB header:oxidoreductase Chain: B: PDB Molecule:putative thioredoxin-like protein; PDBTitle: crystal structure of thioredoxin 2 from yersinia pestis 17 c2i4aA_ 89.9 24 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of thioredoxin from the acidophile2 acetobacter aceti 18 c3ul3A_ 89.8 5 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: structural insights into thioredoxin-2: a component of malaria2 parasite protein secretion machinery 19 d1ep7a_ 88.6 13 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 20 c1w89E_ 88.6 17 PDB header:electron transport Chain: E: PDB Molecule:thioredoxin; PDBTitle: structure of the reduced form of human thioredoxin 2 21 d2hfda1 88.5 14 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:HyaE-like 22 d1r26a_ not modelled 88.4 15 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 23 d1thxa_ not modelled 88.3 26 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 24 c3p2aA_ not modelled 87.9 17 PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin-like protein; PDBTitle: crystal structure of thioredoxin 2 from yersinia pestis 25 c2o7kA_ not modelled 87.7 21 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: s. aureus thioredoxin 26 c2l6dA_ not modelled 87.5 21 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: solution structure of desulfothioredoxin from desulfovibrio vulgaris2 hildenborough in its reduced form 27 c3tcoA_ not modelled 87.3 14 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin (trxa-1); PDBTitle: crystallographic and spectroscopic characterization of sulfolobus2 solfataricus trxa1 provide insights into the determinants of3 thioredoxin fold stability 28 c2vm2C_ not modelled 87.1 8 PDB header:oxidoreductase Chain: C: PDB Molecule:thioredoxin h isoform 1.; PDBTitle: crystal structure of barley thioredoxin h isoform 12 crystallized using peg as precipitant 29 d1m7ta_ not modelled 86.9 30 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 30 d2trxa_ not modelled 86.8 33 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 31 c3hypB_ not modelled 86.8 21 PDB header:electron transport Chain: B: PDB Molecule:thioredoxin; PDBTitle: crystal structure of bacteroides fragilis trxp_s105g mutant 32 d1fb6a_ not modelled 86.5 21 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 33 c2dj1A_ not modelled 85.9 14 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a4; PDBTitle: the solution structure of the first thioredoxin domain of2 mouse protein disulfide-isomerase a4 34 c3dmlA_ not modelled 85.9 14 PDB header:oxidoreductase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of the periplasmic thioredoxin soxs from2 paracoccus pantotrophus (reduced form) 35 d1nhoa_ not modelled 85.9 23 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 36 c2dizA_ not modelled 85.6 19 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin domain-containing protein 5; PDBTitle: the solution structure of the third thioredoxin domain of2 human thioredoxin domain-containing protein 5 37 c2j23A_ not modelled 85.5 20 PDB header:immune protein Chain: A: PDB Molecule:thioredoxin; PDBTitle: cross-reactivity and crystal structure of malassezia2 sympodialis thioredoxin (mala s 13), a member of a new pan-3 allergen family 38 c3hz4A_ not modelled 85.4 19 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of thioredoxin from methanosarcina mazei 39 d1xwaa_ not modelled 85.3 14 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 40 c2xbqB_ not modelled 85.2 10 PDB header:oxidoreductase Chain: B: PDB Molecule:thioredoxin; PDBTitle: crystal structure of reduced schistosoma mansoni2 thioredoxin pre-protein at 1.7 angstrom 41 d1nw2a_ not modelled 85.2 26 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 42 c1t00A_ not modelled 85.1 19 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: the structure of thioredoxin from s. coelicolor 43 c1x5eA_ not modelled 85.0 12 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin domain containing protein 1; PDBTitle: the solution structure of the thioredoxin-like domain of2 human thioredoxin-related transmembrane protein 44 c2yzuA_ not modelled 84.8 14 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of oxidized thioredoxin from thermus thermophilus2 hb8 45 d1zmaa1 not modelled 84.6 21 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 46 d1syra_ not modelled 84.2 7 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 47 c2i1uA_ not modelled 84.1 18 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: mycobacterium tuberculosis thioredoxin c 48 c2l5lA_ not modelled 84.1 17 PDB header:transport protein Chain: A: PDB Molecule:thioredoxin; PDBTitle: solution structure of thioredoxin from bacteroides vulgatus 49 c2f51B_ not modelled 83.8 16 PDB header:electron transport Chain: B: PDB Molecule:thioredoxin; PDBTitle: structure of trichomonas vaginalis thioredoxin 50 c2vimA_ not modelled 83.6 9 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: x-ray structure of fasciola hepatica thioredoxin 51 c3d22A_ not modelled 83.4 13 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin h-type; PDBTitle: crystal structure of a poplar thioredoxin h mutant,2 pttrxh4c61s 52 c3ewlA_ not modelled 82.8 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized conserved protein bf1870; PDBTitle: crystal structure of conserved protein bf1870 of unknown function from2 bacteroides fragilis 53 c3idvA_ not modelled 82.5 11 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a4; PDBTitle: crystal structure of the a0a fragment of erp72 54 c3cxgA_ not modelled 81.6 17 PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin; PDBTitle: crystal structure of plasmodium falciparum thioredoxin, pfi0790w 55 c2kucA_ not modelled 81.1 26 PDB header:isomerase Chain: A: PDB Molecule:putative disulphide-isomerase; PDBTitle: solution structure of a putative disulphide-isomerase from bacteroides2 thetaiotaomicron 56 d1gh2a_ not modelled 81.1 17 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 57 c1v98A_ not modelled 81.1 29 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure analysis of thioredoxin from thermus thermophilus 58 c2i9hA_ not modelled 80.8 14 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin i; PDBTitle: nmr solution structure of the reduced form of thioredoxin 12 from yeast (trx1) 59 c2wz9A_ not modelled 80.6 19 PDB header:protein binding Chain: A: PDB Molecule:glutaredoxin-3; PDBTitle: crystal structure of the thioredoxin domain of human txnl2 60 d1a8la1 not modelled 80.4 12 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 61 d1fo5a_ not modelled 79.9 28 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 62 c1x5dA_ not modelled 79.8 21 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a6; PDBTitle: the solution structure of the second thioredoxin-like2 domain of human protein disulfide-isomerase a6 63 c3d6iB_ not modelled 79.7 10 PDB header:oxidoreductase Chain: B: PDB Molecule:monothiol glutaredoxin-3; PDBTitle: structure of the thioredoxin-like domain of yeast2 glutaredoxin 3 64 c2l57A_ not modelled 79.6 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of an uncharacterized thioredoin-like protein from2 clostridium perfringens 65 c3g9bA_ not modelled 78.9 30 PDB header:transferase Chain: A: PDB Molecule:dolichyl-diphosphooligosaccharide-protein PDBTitle: crystal structure of reduced ost6l 66 d1ti3a_ not modelled 78.4 7 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 67 d1v58a1 not modelled 78.4 16 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:DsbC/DsbG C-terminal domain-like 68 c3l9vE_ not modelled 77.5 34 PDB header:oxidoreductase Chain: E: PDB Molecule:putative thiol-disulfide isomerase or thioredoxin; PDBTitle: crystal structure of salmonella enterica serovar typhimurium srga 69 d1oaza_ not modelled 77.5 33 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 70 c2hyxA_ not modelled 77.4 13 PDB header:unknown function Chain: A: PDB Molecule:protein dipz; PDBTitle: structure of the c-terminal domain of dipz from mycobacterium2 tuberculosis 71 c2albA_ not modelled 77.4 14 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a3; PDBTitle: nmr structure of the n-terminal domain a of the2 glycoprotein chaperone erp57 72 c3feuA_ not modelled 77.2 31 PDB header:oxidoreductase Chain: A: PDB Molecule:putative lipoprotein; PDBTitle: crystal structure of dsba-like thioredoxin domain vf_a0457 from vibrio2 fischeri 73 c3kzqE_ not modelled 76.7 23 PDB header:structural genomics, unknown function Chain: E: PDB Molecule:putative uncharacterized protein vp2116; PDBTitle: the crystal structure of the protein with unknown function from vibrio2 parahaemolyticus rimd 2210633 74 c2dmlA_ not modelled 76.5 17 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a6; PDBTitle: the solution structure of the first thioredoxin domain of2 mouse protein disulfide-isomerase a6 75 c2p0oA_ not modelled 76.4 10 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein duf871; PDBTitle: crystal structure of a conserved protein from locus ef_2437 in2 enterococcus faecalis with an unknown function 76 c3gykC_ not modelled 76.0 22 PDB header:oxidoreductase Chain: C: PDB Molecule:27kda outer membrane protein; PDBTitle: the crystal structure of a thioredoxin-like oxidoreductase from2 silicibacter pomeroyi dss-3 77 d1a8ya1 not modelled 76.0 14 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Calsequestrin 78 c2ec4A_ not modelled 75.8 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:fas-associated factor 1; PDBTitle: solution structure of the uas domain from human fas-2 associated factor 1 79 c3dvwA_ not modelled 75.6 18 PDB header:oxidoreductase Chain: A: PDB Molecule:thiol:disulfide interchange protein dsba; PDBTitle: crystal structure of reduced dsba1 from neisseria2 meningitidis 80 c2aytB_ not modelled 75.4 15 PDB header:oxidoreductase Chain: B: PDB Molecule:glutaredoxin-like protein; PDBTitle: the crystal structure of a protein disulfide oxidoreductase from2 aquifex aeolicus 81 c2oe0B_ not modelled 75.2 7 PDB header:electron transport Chain: B: PDB Molecule:thioredoxin-3; PDBTitle: crystal structure of mitochondrial thioredoxin 3 from2 saccharomyces cerevisiae 82 d1fvka_ not modelled 75.2 18 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:DsbA-like 83 c2znmA_ not modelled 74.5 21 PDB header:oxidoreductase Chain: A: PDB Molecule:thiol:disulfide interchange protein dsba; PDBTitle: oxidoreductase nmdsba3 from neisseria meningitidis 84 c3gl5A_ not modelled 74.5 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative dsba oxidoreductase sco1869; PDBTitle: crystal structure of probable dsba oxidoreductase sco1869 from2 streptomyces coelicolor 85 d1zzoa1 not modelled 74.2 15 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like 86 d1f9ma_ not modelled 72.2 24 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 87 c2hlsB_ not modelled 71.3 18 PDB header:oxidoreductase Chain: B: PDB Molecule:protein disulfide oxidoreductase; PDBTitle: the crystal structure of a protein disulfide oxidoreductase from2 aeropyrum pernix k1 88 c3apsA_ not modelled 71.1 9 PDB header:oxidoreductase Chain: A: PDB Molecule:dnaj homolog subfamily c member 10; PDBTitle: crystal structure of trx4 domain of erdj5 89 c3dxbE_ not modelled 70.8 33 PDB header:splicing, transcription Chain: E: PDB Molecule:thioredoxin n-terminally fused to puf60(uhm); PDBTitle: structure of the uhm domain of puf60 fused to thioredoxin 90 c2in3A_ not modelled 70.7 25 PDB header:isomerase Chain: A: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of a putative protein disulfide isomerase from2 nitrosomonas europaea 91 d1j08a1 not modelled 70.4 20 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 92 d2fwha1 not modelled 70.3 16 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 93 c2fgxA_ not modelled 69.0 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative thioredoxin; PDBTitle: solution nmr structure of protein ne2328 from nitrosomonas2 europaea. northeast structural genomics consortium target3 net3. 94 d1meka_ not modelled 68.3 16 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 95 c3h79A_ not modelled 67.0 9 PDB header:unknown function Chain: A: PDB Molecule:thioredoxin-like protein; PDBTitle: crystal structure of trypanosoma cruzi thioredoxin-like hypothetical2 protein q4dv70 96 c3jr7A_ not modelled 65.9 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized egv family protein cog1307; PDBTitle: the crystal structure of the protein of degv family cog1307 with2 unknown function from ruminococcus gnavus atcc 29149 97 d2b5ea4 not modelled 65.3 14 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 98 d1mgpa_ not modelled 65.2 12 Fold:DAK1/DegV-like Superfamily:DAK1/DegV-like Family:DegV-like 99 c1mgpA_ not modelled 65.2 12 PDB header:lipid binding protein Chain: A: PDB Molecule:hypothetical protein tm841; PDBTitle: hypothetical protein tm841 from thermotoga maritima reveals2 fatty acid binding function 100 c3apqB_ not modelled 64.4 19 PDB header:oxidoreductase Chain: B: PDB Molecule:dnaj homolog subfamily c member 10; PDBTitle: crystal structure of j-trx1 fragment of erdj5 101 c3hczA_ not modelled 64.3 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:possible thiol-disulfide isomerase; PDBTitle: the crystal structure of a domain of possible thiol-disulfide2 isomerase from cytophaga hutchinsonii atcc 33406. 102 c2dbcA_ not modelled 63.4 24 PDB header:signaling protein Chain: A: PDB Molecule:unnamed protein product; PDBTitle: solution structure of the thioredoxin-like domain of2 phosducin-like protein 2(pdcl2) 103 d1xfla_ not modelled 62.1 12 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 104 c1yzxB_ not modelled 62.0 14 PDB header:transferase Chain: B: PDB Molecule:glutathione s-transferase kappa 1; PDBTitle: crystal structure of human kappa class glutathione2 transferase 105 c3kp8A_ not modelled 61.9 17 PDB header:oxidoreductase Chain: A: PDB Molecule:vkorc1/thioredoxin domain protein; PDBTitle: the thioredoxin-like domain of a vkor homolog from2 synechococcus sp. 106 d2dlxa1 not modelled 60.9 14 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:UAS domain 107 d1iloa_ not modelled 60.0 22 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 108 d1wjka_ not modelled 59.6 11 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 109 c3h93A_ not modelled 57.4 26 PDB header:transcription regulator Chain: A: PDB Molecule:thiol:disulfide interchange protein dsba; PDBTitle: crystal structure of pseudomonas aeruginosa dsba 110 c1x5cA_ not modelled 57.3 11 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase; PDBTitle: the solution structure of the second thioredoxin-like2 domain of human protein disulfide-isomerase 111 d1z5ye1 not modelled 57.1 14 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like 112 c3gmfA_ not modelled 56.4 14 PDB header:oxidoreductase Chain: A: PDB Molecule:protein-disulfide isomerase; PDBTitle: crystal structure of protein-disulfide isomerase from novosphingobium2 aromaticivorans 113 c3qdnA_ not modelled 56.2 12 PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin protein; PDBTitle: putative thioredoxin protein from salmonella typhimurium 114 c3fysA_ not modelled 55.7 23 PDB header:fatty acid-binding protein Chain: A: PDB Molecule:protein degv; PDBTitle: crystal structure of degv, a fatty acid binding protein2 from bacillus subtilis 115 c1xbsA_ not modelled 55.6 14 PDB header:transcription, cell cycle Chain: A: PDB Molecule:dim1-like protein; PDBTitle: crystal structure of human dim2: a dim1-like protein 116 c2dunA_ 55.3 13 PDB header:transferase Chain: A: PDB Molecule:dna polymerase mu; PDBTitle: solution structure of brct domain of dna polymerase mu 117 c3ghaA_ not modelled 53.7 17 PDB header:oxidoreductase Chain: A: PDB Molecule:disulfide bond formation protein d; PDBTitle: crystal structure of etda-treated bdbd (reduced) 118 d1o73a_ not modelled 52.2 13 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like 119 d1eeja1 not modelled 51.1 18 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:DsbC/DsbG C-terminal domain-like 120 c2remB_ not modelled 49.9 14 PDB header:oxidoreductase Chain: B: PDB Molecule:disulfide oxidoreductase; PDBTitle: crystal structure of oxidoreductase dsba from xylella2 fastidiosa

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0