Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ47719
DateThu Jan 5 12:37:11 GMT 2012
Unique Job ID32d34449a821fb1f

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2vq3B_
Top template information
PDB header:oxidoreductase
Chain: B: PDB Molecule:metalloreductase steap3;
PDBTitle: crystal structure of the membrane proximal oxidoreductase2 domain of human steap3, the dominant ferric reductase of3 the erythroid transferrin cycle
Confidence and coverage
Confidence: 98.2% Coverage: 53%
73 residues ( 53% of your sequence) have been modelled with 98.2% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MVGYHQTNQKTDTGKTLTRRPVLVDHNRLPEGSRGRLAVAVAGDHPAAVQVTMTLVNDTG
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Disorder  ???????



















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   .........70.........80.........90.........100.........110.........120
Sequence  FDPVFSGSIAESWRQQPCTPSYCCDWEAATMLRAFPLAKKGEGRARLPSLYASFGKLGET
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Disorder 



































?????













??


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   .........130.......
Sequence  PTHEDIIDNNRSINWPV
Secondary structure 






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Disorder 










??????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2vq3 chain B

3D model

Region: 4 - 76
Aligned: 73
Modelled: 73
Confidence: 98.2%
Identity: 25%
PDB header:oxidoreductase
Chain: B: PDB Molecule:metalloreductase steap3;
PDBTitle: crystal structure of the membrane proximal oxidoreductase2 domain of human steap3, the dominant ferric reductase of3 the erythroid transferrin cycle

Phyre2

PDB 3dtt chain A

3D model

Region: 9 - 83
Aligned: 75
Modelled: 75
Confidence: 98.0%
Identity: 20%
PDB header:oxidoreductase
Chain: A: PDB Molecule:nadp oxidoreductase;
PDBTitle: crystal structure of a putative f420 dependent nadp-reductase2 (arth_0613) from arthrobacter sp. fb24 at 1.70 a resolution

Phyre2

PDB 2raf chain C

3D model

Region: 30 - 82
Aligned: 53
Modelled: 51
Confidence: 97.8%
Identity: 15%
PDB header:oxidoreductase
Chain: C: PDB Molecule:putative dinucleotide-binding oxidoreductase;
PDBTitle: crystal structure of putative dinucleotide-binding2 oxidoreductase (np_786167.1) from lactobacillus plantarum3 at 1.60 a resolution

Phyre2

PDB 1jay chain A

3D model

Region: 30 - 82
Aligned: 53
Modelled: 53
Confidence: 97.8%
Identity: 25%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2

PDB 1wdk chain A domain 3

3D model

Region: 30 - 67
Aligned: 38
Modelled: 38
Confidence: 78.2%
Identity: 13%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2

PDB 3cum chain A domain 2

3D model

Region: 38 - 67
Aligned: 30
Modelled: 30
Confidence: 71.9%
Identity: 17%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2

PDB 3d1l chain B

3D model

Region: 27 - 68
Aligned: 42
Modelled: 42
Confidence: 70.3%
Identity: 5%
PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nadp oxidoreductase bf3122;
PDBTitle: crystal structure of putative nadp oxidoreductase bf3122 from2 bacteroides fragilis

Phyre2

PDB 3b0v chain D

3D model

Region: 35 - 66
Aligned: 32
Modelled: 32
Confidence: 69.6%
Identity: 19%
PDB header:oxidoreductase/rna
Chain: D: PDB Molecule:trna-dihydrouridine synthase;
PDBTitle: trna-dihydrouridine synthase from thermus thermophilus in complex with2 trna

Phyre2

PDB 1pgj chain A domain 2

3D model

Region: 39 - 69
Aligned: 31
Modelled: 31
Confidence: 64.4%
Identity: 6%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2

PDB 1vpd chain A domain 2

3D model

Region: 38 - 67
Aligned: 30
Modelled: 30
Confidence: 57.6%
Identity: 17%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2

PDB 1f0y chain A domain 2

3D model

Region: 38 - 67
Aligned: 30
Modelled: 30
Confidence: 52.3%
Identity: 10%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2

PDB 2f6r chain A

3D model

Region: 26 - 82
Aligned: 56
Modelled: 57
Confidence: 45.6%
Identity: 18%
PDB header:transferase
Chain: A: PDB Molecule:bifunctional coenzyme a synthase;
PDBTitle: crystal structure of bifunctional coenzyme a synthase (coa synthase):2 (18044849) from mus musculus at 1.70 a resolution

Phyre2

PDB 1mv8 chain A domain 2

3D model

Region: 39 - 64
Aligned: 25
Modelled: 26
Confidence: 43.2%
Identity: 4%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2

PDB 3s5p chain A

3D model

Region: 34 - 83
Aligned: 39
Modelled: 50
Confidence: 40.2%
Identity: 26%
PDB header:isomerase
Chain: A: PDB Molecule:ribose 5-phosphate isomerase;
PDBTitle: crystal structure of ribose-5-phosphate isomerase b rpib from giardia2 lamblia

Phyre2

PDB 2yv3 chain B

3D model

Region: 14 - 94
Aligned: 77
Modelled: 81
Confidence: 37.0%
Identity: 19%
PDB header:oxidoreductase
Chain: B: PDB Molecule:aspartate-semialdehyde dehydrogenase;
PDBTitle: crystal structure of aspartate semialdehyde dehydrogenase from thermus2 thermophilus hb8

Phyre2

PDB 2cvz chain A domain 2

3D model

Region: 35 - 68
Aligned: 32
Modelled: 34
Confidence: 36.4%
Identity: 25%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2

PDB 1nn4 chain A

3D model

Region: 39 - 71
Aligned: 33
Modelled: 33
Confidence: 31.8%
Identity: 15%
Fold: Ribose/Galactose isomerase RpiB/AlsB
Superfamily: Ribose/Galactose isomerase RpiB/AlsB
Family: Ribose/Galactose isomerase RpiB/AlsB

Phyre2

PDB 1vhn chain A

3D model

Region: 29 - 66
Aligned: 37
Modelled: 38
Confidence: 31.4%
Identity: 16%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1i36 chain A domain 2

3D model

Region: 9 - 63
Aligned: 51
Modelled: 51
Confidence: 28.2%
Identity: 8%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2

PDB 1yt8 chain A domain 4

3D model

Region: 5 - 80
Aligned: 75
Modelled: 76
Confidence: 27.5%
Identity: 15%
Fold: Rhodanese/Cell cycle control phosphatase
Superfamily: Rhodanese/Cell cycle control phosphatase
Family: Multidomain sulfurtransferase (rhodanese)

Phyre2
1

c2vq3B_
2

c3dttA_
3

c2rafC_
4

d1jaya_
5

d1wdka3
6

d3cuma2
7

c3d1lB_
8

c3b0vD_
9

d1pgja2
10

d1vpda2
11

d1f0ya2
12

c2f6rA_
13

d1mv8a2
14

c3s5pA_
15

c2yv3B_
16

d2cvza2
17

d1nn4a_
18

d1vhna_
19

d1i36a2
20

d1yt8a4
21



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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2vq3B_



98.2 25 PDB header:oxidoreductase
Chain: B: PDB Molecule:metalloreductase steap3;
PDBTitle: crystal structure of the membrane proximal oxidoreductase2 domain of human steap3, the dominant ferric reductase of3 the erythroid transferrin cycle
2c3dttA_



98.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadp oxidoreductase;
PDBTitle: crystal structure of a putative f420 dependent nadp-reductase2 (arth_0613) from arthrobacter sp. fb24 at 1.70 a resolution
3c2rafC_



97.8 15 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative dinucleotide-binding oxidoreductase;
PDBTitle: crystal structure of putative dinucleotide-binding2 oxidoreductase (np_786167.1) from lactobacillus plantarum3 at 1.60 a resolution
4d1jaya_



97.8 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
5d1wdka3



78.2 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
6d3cuma2



71.9 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
7c3d1lB_



70.3 5 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nadp oxidoreductase bf3122;
PDBTitle: crystal structure of putative nadp oxidoreductase bf3122 from2 bacteroides fragilis
8c3b0vD_



69.6 19 PDB header:oxidoreductase/rna
Chain: D: PDB Molecule:trna-dihydrouridine synthase;
PDBTitle: trna-dihydrouridine synthase from thermus thermophilus in complex with2 trna
9d1pgja2



64.4 6 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
10d1vpda2



57.6 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
11d1f0ya2



52.3 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
12c2f6rA_



45.6 18 PDB header:transferase
Chain: A: PDB Molecule:bifunctional coenzyme a synthase;
PDBTitle: crystal structure of bifunctional coenzyme a synthase (coa synthase):2 (18044849) from mus musculus at 1.70 a resolution
13d1mv8a2



43.2 4 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
14c3s5pA_



40.2 26 PDB header:isomerase
Chain: A: PDB Molecule:ribose 5-phosphate isomerase;
PDBTitle: crystal structure of ribose-5-phosphate isomerase b rpib from giardia2 lamblia
15c2yv3B_



37.0 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:aspartate-semialdehyde dehydrogenase;
PDBTitle: crystal structure of aspartate semialdehyde dehydrogenase from thermus2 thermophilus hb8
16d2cvza2



36.4 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
17d1nn4a_



31.8 15 Fold:Ribose/Galactose isomerase RpiB/AlsB
Superfamily:Ribose/Galactose isomerase RpiB/AlsB
Family:Ribose/Galactose isomerase RpiB/AlsB
18d1vhna_



31.4 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
19d1i36a2



28.2 8 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
20d1yt8a4



27.5 15 Fold:Rhodanese/Cell cycle control phosphatase
Superfamily:Rhodanese/Cell cycle control phosphatase
Family:Multidomain sulfurtransferase (rhodanese)
21c3he8A_



not modelled 26.1 13 PDB header:isomerase
Chain: A: PDB Molecule:ribose-5-phosphate isomerase;
PDBTitle: structural study of clostridium thermocellum ribose-5-phosphate2 isomerase b
22c3i2vA_



not modelled 26.0 12 PDB header:transferase
Chain: A: PDB Molecule:adenylyltransferase and sulfurtransferase mocs3;
PDBTitle: crystal structure of human mocs3 rhodanese-like domain
23d1xrsb2



not modelled 25.4 5 Fold:Dodecin subunit-like
Superfamily:D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain
Family:D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain
24d1b25a1



not modelled 22.6 19 Fold:Aldehyde ferredoxin oxidoreductase, C-terminal domains
Superfamily:Aldehyde ferredoxin oxidoreductase, C-terminal domains
Family:Aldehyde ferredoxin oxidoreductase, C-terminal domains
25c3aaxB_



not modelled 21.6 15 PDB header:transferase
Chain: B: PDB Molecule:putative thiosulfate sulfurtransferase;
PDBTitle: crystal structure of probable thiosulfate sulfurtransferase2 cysa3 (rv3117) from mycobacterium tuberculosis: monoclinic3 form
26d2vvpa1



not modelled 21.6 27 Fold:Ribose/Galactose isomerase RpiB/AlsB
Superfamily:Ribose/Galactose isomerase RpiB/AlsB
Family:Ribose/Galactose isomerase RpiB/AlsB
27d1t4aa_



not modelled 21.2 8 Fold:PurS-like
Superfamily:PurS-like
Family:PurS subunit of FGAM synthetase
28d1umka2



not modelled 20.0 12 Fold:Ferredoxin reductase-like, C-terminal NADP-linked domain
Superfamily:Ferredoxin reductase-like, C-terminal NADP-linked domain
Family:Reductases
29d2i76a2



not modelled 19.7 9 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
30c2zayA_



not modelled 19.4 16 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator receiver protein;
PDBTitle: crystal structure of response regulator from desulfuromonas2 acetoxidans
31c2yx5A_



not modelled 19.1 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:upf0062 protein mj1593;
PDBTitle: crystal structure of methanocaldococcus jannaschii purs, one of the2 subunits of formylglycinamide ribonucleotide amidotransferase in the3 purine biosynthetic pathway
32d3bula2



not modelled 18.8 10 Fold:Flavodoxin-like
Superfamily:Cobalamin (vitamin B12)-binding domain
Family:Cobalamin (vitamin B12)-binding domain
33d2pgda2



not modelled 18.5 11 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
34d2a9pa1



not modelled 17.1 11 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
35d1aora1



not modelled 17.0 15 Fold:Aldehyde ferredoxin oxidoreductase, C-terminal domains
Superfamily:Aldehyde ferredoxin oxidoreductase, C-terminal domains
Family:Aldehyde ferredoxin oxidoreductase, C-terminal domains
36d1qx4a2



not modelled 16.9 10 Fold:Ferredoxin reductase-like, C-terminal NADP-linked domain
Superfamily:Ferredoxin reductase-like, C-terminal NADP-linked domain
Family:Reductases
37c3kevA_



not modelled 16.3 11 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:galieria sulfuraria dcun1 domain-containing protein;
PDBTitle: x-ray crystal structure of a dcun1 domain-containing protein from2 galdieria sulfuraria
38c3dzbA_



not modelled 15.9 2 PDB header:biosynthetic protein
Chain: A: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 thermophilus
39c3hpxB_



not modelled 15.9 18 PDB header:transferase
Chain: B: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of mycobacterium tuberculosis leua active site2 domain 1-425 (truncation mutant delta:426-644)
40c1bmtB_



not modelled 15.8 13 PDB header:methyltransferase
Chain: B: PDB Molecule:methionine synthase;
PDBTitle: how a protein binds b12: a 3.o angstrom x-ray structure of2 the b12-binding domains of methionine synthase
41d1o1xa_



not modelled 15.7 20 Fold:Ribose/Galactose isomerase RpiB/AlsB
Superfamily:Ribose/Galactose isomerase RpiB/AlsB
Family:Ribose/Galactose isomerase RpiB/AlsB
42c3cumA_



not modelled 15.3 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable 3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of a possible 3-hydroxyisobutyrate dehydrogenase2 from pseudomonas aeruginosa pao1
43c1wsrA_



not modelled 15.1 16 PDB header:transferase
Chain: A: PDB Molecule:aminomethyltransferase;
PDBTitle: crystal structure of human t-protein of glycine cleavage2 system
44c3ch4B_



not modelled 15.1 19 PDB header:transferase
Chain: B: PDB Molecule:phosphomevalonate kinase;
PDBTitle: the crystal structure of human phosphomavelonate kinase at2 1.8 a resolution
45c1b4nD_



not modelled 14.8 19 PDB header:oxidoreductase
Chain: D: PDB Molecule:formaldehyde ferredoxin oxidoreductase;
PDBTitle: formaldehyde ferredoxin oxidoreductase from pyrococcus furiosus,2 complexed with glutarate
46c1aorB_



not modelled 14.6 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:aldehyde ferredoxin oxidoreductase;
PDBTitle: structure of a hyperthermophilic tungstopterin enzyme,2 aldehyde ferredoxin oxidoreductase
47d2bjca1



not modelled 14.1 6 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:GalR/LacI-like bacterial regulator
48c3aerB_



not modelled 13.8 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:light-independent protochlorophyllide reductase subunit b;
PDBTitle: structure of the light-independent protochlorophyllide reductase2 catalyzing a key reduction for greening in the dark
49d1uf9a_



not modelled 13.4 9 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
50d3ci0k2



not modelled 13.4 28 Fold:SAM domain-like
Superfamily:GspK insert domain-like
Family:GspK insert domain-like
51c2jrlA_



not modelled 13.0 16 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulator (ntrc family);
PDBTitle: solution structure of the beryllofluoride-activated ntrc4 receiver2 domain dimer
52c3g0oA_



not modelled 12.7 7 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of 3-hydroxyisobutyrate dehydrogenase2 (ygbj) from salmonella typhimurium
53c3crnA_



not modelled 12.5 14 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator receiver domain protein, chey-like;
PDBTitle: crystal structure of response regulator receiver domain protein (chey-2 like) from methanospirillum hungatei jf-1
54c3pefA_



not modelled 12.5 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase, nad-binding;
PDBTitle: crystal structure of gamma-hydroxybutyrate dehydrogenase from2 geobacter metallireducens in complex with nadp+
55c1yb4A_



not modelled 12.2 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:tartronic semialdehyde reductase;
PDBTitle: crystal structure of the tartronic semialdehyde reductase from2 salmonella typhimurium lt2
56c3ckyA_



not modelled 12.1 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-hydroxymethyl glutarate dehydrogenase;
PDBTitle: structural and kinetic properties of a beta-hydroxyacid dehydrogenase2 involved in nicotinate fermentation
57c2l8nA_



not modelled 11.9 17 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional repressor cytr;
PDBTitle: nmr structure of the cytidine repressor dna binding domain in presence2 of operator half-site dna
58d1vhta_



not modelled 11.7 21 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
59d1jdqa_



not modelled 11.5 19 Fold:IF3-like
Superfamily:SirA-like
Family:SirA-like
60c2zwmA_



not modelled 11.4 11 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulatory protein yycf;
PDBTitle: crystal structure of yycf receiver domain from bacillus2 subtilis
61d2hsga1



not modelled 11.3 17 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:GalR/LacI-like bacterial regulator
62c3cfyA_



not modelled 10.9 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative luxo repressor protein;
PDBTitle: crystal structure of signal receiver domain of putative luxo2 repressor protein from vibrio parahaemolyticus
63d1uxca_



not modelled 10.7 22 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:GalR/LacI-like bacterial regulator
64c3pduF_



not modelled 10.7 9 PDB header:oxidoreductase
Chain: F: PDB Molecule:3-hydroxyisobutyrate dehydrogenase family protein;
PDBTitle: crystal structure of gamma-hydroxybutyrate dehydrogenase from2 geobacter sulfurreducens in complex with nadp+
65c2is9A_



not modelled 10.6 6 PDB header:transcription
Chain: A: PDB Molecule:defective in cullin neddylation protein 1;
PDBTitle: structure of yeast dcn-1
66d1qpza1



not modelled 10.6 5 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:GalR/LacI-like bacterial regulator
67c2gz3D_



not modelled 10.6 18 PDB header:oxidoreductase
Chain: D: PDB Molecule:aspartate beta-semialdehyde dehydrogenase;
PDBTitle: structure of aspartate semialdehyde dehydrogenase (asadh) from2 streptococcus pneumoniae complexed with nadp and aspartate-3 semialdehyde
68c3gl9B_



not modelled 10.6 8 PDB header:signaling protein
Chain: B: PDB Molecule:response regulator;
PDBTitle: the structure of a histidine kinase-response regulator2 complex sheds light into two-component signaling and3 reveals a novel cis autophosphorylation mechanism
69d2g5ca2



not modelled 10.1 8 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
70d1lcda_



not modelled 10.1 6 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:GalR/LacI-like bacterial regulator
71d1efaa1



not modelled 10.0 6 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:GalR/LacI-like bacterial regulator
72c1vpdA_



not modelled 10.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:tartronate semialdehyde reductase;
PDBTitle: x-ray crystal structure of tartronate semialdehyde reductase2 [salmonella typhimurium lt2]
73d1dcja_



not modelled 9.9 14 Fold:IF3-like
Superfamily:SirA-like
Family:SirA-like
74c3hdvB_



not modelled 9.8 20 PDB header:transcription regulator
Chain: B: PDB Molecule:response regulator;
PDBTitle: crystal structure of response regulator receiver protein from2 pseudomonas putida
75c3eodA_



not modelled 9.7 8 PDB header:signaling protein
Chain: A: PDB Molecule:protein hnr;
PDBTitle: crystal structure of n-terminal domain of e. coli rssb
76d2hjsa1



not modelled 9.5 8 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
77d1qkka_



not modelled 9.4 16 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
78c3iwdC_



not modelled 9.4 13 PDB header:lyase
Chain: C: PDB Molecule:s-adenosylmethionine decarboxylase;
PDBTitle: t. maritima adometdc complex with 5'-deoxy-5'-dimethyl2 thioadenosine
79d2cnda2



not modelled 9.4 9 Fold:Ferredoxin reductase-like, C-terminal NADP-linked domain
Superfamily:Ferredoxin reductase-like, C-terminal NADP-linked domain
Family:Reductases
80c2rhmD_



not modelled 9.4 7 PDB header:unknown function
Chain: D: PDB Molecule:putative kinase;
PDBTitle: crystal structure of a putative kinase (caur_3907) from chloroflexus2 aurantiacus j-10-fl at 1.70 a resolution
81c3lteH_



not modelled 9.3 9 PDB header:transcription
Chain: H: PDB Molecule:response regulator;
PDBTitle: crystal structure of response regulator (signal receiver domain) from2 bermanella marisrubri
82c3hzuA_



not modelled 9.3 19 PDB header:transferase
Chain: A: PDB Molecule:thiosulfate sulfurtransferase ssea;
PDBTitle: crystal structure of probable thiosulfate sulfurtransferase ssea2 (rhodanese) from mycobacterium tuberculosis
83d2f1ka2



not modelled 9.3 6 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
84c2yxbA_



not modelled 9.2 34 PDB header:isomerase
Chain: A: PDB Molecule:coenzyme b12-dependent mutase;
PDBTitle: crystal structure of the methylmalonyl-coa mutase alpha-subunit from2 aeropyrum pernix
85d1uxda_



not modelled 9.2 22 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:GalR/LacI-like bacterial regulator
86d1xhfa1



not modelled 9.1 14 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
87d1m98a1



not modelled 9.0 36 Fold:Orange carotenoid protein, N-terminal domain
Superfamily:Orange carotenoid protein, N-terminal domain
Family:Orange carotenoid protein, N-terminal domain
88c2k29A_



not modelled 9.0 11 PDB header:transcription
Chain: A: PDB Molecule:antitoxin relb;
PDBTitle: structure of the dbd domain of e. coli antitoxin relb
89c1zuiA_



not modelled 8.7 5 PDB header:transferase
Chain: A: PDB Molecule:shikimate kinase;
PDBTitle: structural basis for shikimate-binding specificity of helicobacter2 pylori shikimate kinase
90d1fmfa_



not modelled 8.6 21 Fold:Flavodoxin-like
Superfamily:Cobalamin (vitamin B12)-binding domain
Family:Cobalamin (vitamin B12)-binding domain
91c2lcvA_



not modelled 8.5 17 PDB header:transcription regulator
Chain: A: PDB Molecule:hth-type transcriptional repressor cytr;
PDBTitle: structure of the cytidine repressor dna-binding domain; an alternate2 calculation
92c2nqqA_



not modelled 8.3 21 PDB header:biosynthetic protein
Chain: A: PDB Molecule:molybdopterin biosynthesis protein moea;
PDBTitle: moea r137q
93c3nhzA_



not modelled 8.2 18 PDB header:dna binding protein
Chain: A: PDB Molecule:two component system transcriptional regulator mtra;
PDBTitle: structure of n-terminal domain of mtra
94c1ys4A_



not modelled 8.1 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:aspartate-semialdehyde dehydrogenase;
PDBTitle: structure of aspartate-semialdehyde dehydrogenase from2 methanococcus jannaschii
95c2uyyD_



not modelled 8.0 16 PDB header:cytokine
Chain: D: PDB Molecule:n-pac protein;
PDBTitle: structure of the cytokine-like nuclear factor n-pac
96c3h0kA_



not modelled 8.0 6 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:upf0200 protein sso1041;
PDBTitle: crystal structure of an adenylated kinase related protein from2 sulfolobus solfataricus to 3.25a
97d1pj5a4



not modelled 7.9 15 Fold:Folate-binding domain
Superfamily:Folate-binding domain
Family:Aminomethyltransferase folate-binding domain
98c2i76B_



not modelled 7.9 3 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of protein tm1727 from thermotoga maritima
99c2pjuD_



not modelled 7.9 15 PDB header:transcription
Chain: D: PDB Molecule:propionate catabolism operon regulatory protein;
PDBTitle: crystal structure of propionate catabolism operon2 regulatory protein prpr

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0