Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP75976
DateThu Jan 5 12:16:47 GMT 2012
Unique Job ID2ede2d7bbe41c231

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1rzsa_
Top template information
Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Phage repressors
Confidence and coverage
Confidence: 89.1% Coverage: 24%
44 residues ( 24% of your sequence) have been modelled with 89.1% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
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3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MGKHHWKIEKQPEWYVKAVRKTIAALPSGYAEAADWLDVTENALFNRLRADGDQIFPLGW
Secondary structure 


















SS confidence 



























































Disorder  ?????????








































???????


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   .........70.........80.........90.........100.........110.........120
Sequence  AMVLQRAGGTHFIADAVAQSANGVFVSLPDVEDVDNADINQRLLEVIEQIGSYSKQIRSA
Secondary structure 











SS confidence 



























































Disorder 




























??????
























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   .........130.........140.........150.........160.........170.........180
Sequence  IEDGVVEPHEKTAINDELYLSISKLQEHAALVYKIFCISESNDARECAAPGVVASIASGC
Secondary structure 

















SS confidence 



























































Disorder 



?
































???















???
Disorder confidence 



























































 
   .....
Sequence  GETNA
Secondary structure 




SS confidence 




Disorder  ?????
Disorder confidence 




 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1rzs chain A

3D model

Region: 20 - 69
Aligned: 44
Modelled: 50
Confidence: 89.1%
Identity: 16%
Fold: lambda repressor-like DNA-binding domains
Superfamily: lambda repressor-like DNA-binding domains
Family: Phage repressors

Phyre2

PDB 1fip chain A

3D model

Region: 17 - 52
Aligned: 36
Modelled: 36
Confidence: 88.7%
Identity: 14%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: Homeodomain-like
Family: FIS-like

Phyre2

PDB 3bd1 chain B

3D model

Region: 16 - 69
Aligned: 50
Modelled: 54
Confidence: 87.8%
Identity: 20%
PDB header:transcription
Chain: B: PDB Molecule:cro protein;
PDBTitle: structure of the cro protein from putative prophage element xfaso 1 in2 xylella fastidiosa strain ann-1

Phyre2

PDB 1etx chain A

3D model

Region: 17 - 52
Aligned: 36
Modelled: 36
Confidence: 86.7%
Identity: 14%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: Homeodomain-like
Family: FIS-like

Phyre2

PDB 3e7l chain D

3D model

Region: 17 - 52
Aligned: 36
Modelled: 36
Confidence: 84.3%
Identity: 6%
PDB header:transcription regulator
Chain: D: PDB Molecule:transcriptional regulator (ntrc family);
PDBTitle: crystal structure of sigma54 activator ntrc4's dna binding2 domain

Phyre2

PDB 1g2h chain A

3D model

Region: 17 - 52
Aligned: 35
Modelled: 36
Confidence: 83.4%
Identity: 23%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: Homeodomain-like
Family: FIS-like

Phyre2

PDB 1eto chain B

3D model

Region: 17 - 52
Aligned: 36
Modelled: 36
Confidence: 83.2%
Identity: 14%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: Homeodomain-like
Family: FIS-like

Phyre2

PDB 3trb chain A

3D model

Region: 11 - 80
Aligned: 66
Modelled: 70
Confidence: 82.8%
Identity: 17%
PDB header:dna binding protein
Chain: A: PDB Molecule:virulence-associated protein i;
PDBTitle: structure of an addiction module antidote protein of a higa (higa)2 family from coxiella burnetii

Phyre2

PDB 1umq chain A

3D model

Region: 17 - 54
Aligned: 38
Modelled: 38
Confidence: 82.8%
Identity: 13%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: Homeodomain-like
Family: FIS-like

Phyre2

PDB 1umq chain A

3D model

Region: 17 - 54
Aligned: 38
Modelled: 38
Confidence: 82.8%
Identity: 13%
PDB header:dna-binding protein
Chain: A: PDB Molecule:photosynthetic apparatus regulatory protein;
PDBTitle: solution structure and dna binding of the effector domain2 from the global regulator prra(rega) from r. sphaeroides:3 insights into dna binding specificity

Phyre2

PDB 2fjr chain B

3D model

Region: 16 - 71
Aligned: 53
Modelled: 56
Confidence: 82.2%
Identity: 21%
PDB header:transcription regulator
Chain: B: PDB Molecule:repressor protein ci;
PDBTitle: crystal structure of bacteriophage 186

Phyre2

PDB 1ntc chain A

3D model

Region: 17 - 48
Aligned: 32
Modelled: 32
Confidence: 81.1%
Identity: 19%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: Homeodomain-like
Family: FIS-like

Phyre2

PDB 3cec chain A

3D model

Region: 17 - 71
Aligned: 53
Modelled: 55
Confidence: 80.3%
Identity: 17%
PDB header:transcription
Chain: A: PDB Molecule:putative antidote protein of plasmid maintenance system;
PDBTitle: crystal structure of a putative antidote protein of plasmid2 maintenance system (npun_f2943) from nostoc punctiforme pcc 73102 at3 1.60 a resolution

Phyre2

PDB 2ou3 chain A domain 1

3D model

Region: 109 - 141
Aligned: 33
Modelled: 33
Confidence: 74.8%
Identity: 21%
Fold: TerB-like
Superfamily: TerB-like
Family: COG3793-like

Phyre2

PDB 3onq chain B

3D model

Region: 10 - 49
Aligned: 39
Modelled: 40
Confidence: 70.1%
Identity: 21%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:regulator of polyketide synthase expression;
PDBTitle: crystal structure of regulator of polyketide synthase expression2 bad_0249 from bifidobacterium adolescentis

Phyre2

PDB 3omt chain A

3D model

Region: 30 - 71
Aligned: 40
Modelled: 42
Confidence: 66.3%
Identity: 13%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: putative antitoxin component, chu_2935 protein, from xre family from2 prevotella buccae.

Phyre2

PDB 1vz0 chain A domain 1

3D model

Region: 18 - 49
Aligned: 31
Modelled: 32
Confidence: 61.2%
Identity: 16%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: KorB DNA-binding domain-like
Family: KorB DNA-binding domain-like

Phyre2

PDB 2jxu chain A

3D model

Region: 108 - 139
Aligned: 32
Modelled: 32
Confidence: 58.9%
Identity: 22%
PDB header:unknown function
Chain: A: PDB Molecule:terb;
PDBTitle: nmr solution structure of kp-terb, a tellurite resistance2 protein from klebsiella pneumoniae

Phyre2

PDB 3mn2 chain B

3D model

Region: 13 - 83
Aligned: 71
Modelled: 71
Confidence: 58.3%
Identity: 14%
PDB header:transcription regulator
Chain: B: PDB Molecule:probable arac family transcriptional regulator;
PDBTitle: the crystal structure of a probable arac family transcriptional2 regulator from rhodopseudomonas palustris cga009

Phyre2

PDB 3bdn chain B

3D model

Region: 13 - 71
Aligned: 57
Modelled: 59
Confidence: 57.7%
Identity: 12%
PDB header:transcription/dna
Chain: B: PDB Molecule:lambda repressor;
PDBTitle: crystal structure of the lambda repressor

Phyre2

PDB 2a61 chain A domain 1

3D model

Region: 10 - 148
Aligned: 134
Modelled: 134
Confidence: 54.0%
Identity: 17%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: MarR-like transcriptional regulators

Phyre2
1

d1rzsa_
2

d1fipa_
3

c3bd1B_
4

d1etxa_
5

c3e7lD_
6

d1g2ha_
7

d1etob_
8

c3trbA_
9

d1umqa_
10

c1umqA_
11

c2fjrB_
12

d1ntca_
13

c3cecA_
14

d2ou3a1
15

c3onqB_
16

c3omtA_
17

d1vz0a1
18

c2jxuA_
19

c3mn2B_
20

c3bdnB_
21



22



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d2a61a1
28



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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1rzsa_



89.1 16 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Phage repressors
2d1fipa_



88.7 14 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:FIS-like
3c3bd1B_



87.8 20 PDB header:transcription
Chain: B: PDB Molecule:cro protein;
PDBTitle: structure of the cro protein from putative prophage element xfaso 1 in2 xylella fastidiosa strain ann-1
4d1etxa_



86.7 14 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:FIS-like
5c3e7lD_



84.3 6 PDB header:transcription regulator
Chain: D: PDB Molecule:transcriptional regulator (ntrc family);
PDBTitle: crystal structure of sigma54 activator ntrc4's dna binding2 domain
6d1g2ha_



83.4 23 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:FIS-like
7d1etob_



83.2 14 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:FIS-like
8c3trbA_



82.8 17 PDB header:dna binding protein
Chain: A: PDB Molecule:virulence-associated protein i;
PDBTitle: structure of an addiction module antidote protein of a higa (higa)2 family from coxiella burnetii
9d1umqa_



82.8 13 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:FIS-like
10c1umqA_



82.8 13 PDB header:dna-binding protein
Chain: A: PDB Molecule:photosynthetic apparatus regulatory protein;
PDBTitle: solution structure and dna binding of the effector domain2 from the global regulator prra(rega) from r. sphaeroides:3 insights into dna binding specificity
11c2fjrB_



82.2 21 PDB header:transcription regulator
Chain: B: PDB Molecule:repressor protein ci;
PDBTitle: crystal structure of bacteriophage 186
12d1ntca_



81.1 19 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:FIS-like
13c3cecA_



80.3 17 PDB header:transcription
Chain: A: PDB Molecule:putative antidote protein of plasmid maintenance system;
PDBTitle: crystal structure of a putative antidote protein of plasmid2 maintenance system (npun_f2943) from nostoc punctiforme pcc 73102 at3 1.60 a resolution
14d2ou3a1



74.8 21 Fold:TerB-like
Superfamily:TerB-like
Family:COG3793-like
15c3onqB_



70.1 21 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:regulator of polyketide synthase expression;
PDBTitle: crystal structure of regulator of polyketide synthase expression2 bad_0249 from bifidobacterium adolescentis
16c3omtA_



66.3 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: putative antitoxin component, chu_2935 protein, from xre family from2 prevotella buccae.
17d1vz0a1



61.2 16 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:KorB DNA-binding domain-like
Family:KorB DNA-binding domain-like
18c2jxuA_



58.9 22 PDB header:unknown function
Chain: A: PDB Molecule:terb;
PDBTitle: nmr solution structure of kp-terb, a tellurite resistance2 protein from klebsiella pneumoniae
19c3mn2B_



58.3 14 PDB header:transcription regulator
Chain: B: PDB Molecule:probable arac family transcriptional regulator;
PDBTitle: the crystal structure of a probable arac family transcriptional2 regulator from rhodopseudomonas palustris cga009
20c3bdnB_



57.7 12 PDB header:transcription/dna
Chain: B: PDB Molecule:lambda repressor;
PDBTitle: crystal structure of the lambda repressor
21d1utxa_



not modelled 57.4 14 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:SinR domain-like
22c3bs3A_



not modelled 56.8 10 PDB header:dna binding protein
Chain: A: PDB Molecule:putative dna-binding protein;
PDBTitle: crystal structure of a putative dna-binding protein from bacteroides2 fragilis
23c3mklB_



not modelled 55.3 22 PDB header:transcription regulator
Chain: B: PDB Molecule:hth-type transcriptional regulator gadx;
PDBTitle: crystal structure of dna-binding transcriptional dual regulator from2 escherichia coli k-12
24d2cg4a1



not modelled 54.8 18 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Lrp/AsnC-like transcriptional regulator N-terminal domain
25d2icta1



not modelled 54.8 14 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:SinR domain-like
26d1ctda_



not modelled 54.4 24 Fold:EF Hand-like
Superfamily:EF-hand
Family:Calmodulin-like
27d2a61a1



54.0 17 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
28c3mkyP_



not modelled 53.5 7 PDB header:dna binding protein/dna
Chain: P: PDB Molecule:protein sopb;
PDBTitle: structure of sopb(155-323)-18mer dna complex, i23 form
29c3eusB_



not modelled 51.8 15 PDB header:dna binding protein
Chain: B: PDB Molecule:dna-binding protein;
PDBTitle: the crystal structure of the dna binding protein from silicibacter2 pomeroyi
30d2cfxa1



not modelled 51.4 9 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Lrp/AsnC-like transcriptional regulator N-terminal domain
31d2cyya1



not modelled 50.4 15 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Lrp/AsnC-like transcriptional regulator N-terminal domain
32c3lisB_



not modelled 50.4 12 PDB header:transcription
Chain: B: PDB Molecule:csp231i c protein;
PDBTitle: crystal structure of the restriction-modification controller protein2 c.csp231i (monoclinic form)
33c1nh2D_



not modelled 49.0 12 PDB header:transcription/dna
Chain: D: PDB Molecule:transcription initiation factor iia small chain;
PDBTitle: crystal structure of a yeast tfiia/tbp/dna complex
34c3op9A_



not modelled 47.7 13 PDB header:transcription regulator
Chain: A: PDB Molecule:pli0006 protein;
PDBTitle: crystal structure of transcriptional regulator from listeria innocua
35c2l4aA_



not modelled 47.6 9 PDB header:dna binding protein
Chain: A: PDB Molecule:leucine responsive regulatory protein;
PDBTitle: nmr structure of the dna-binding domain of e.coli lrp
36d1i1ga1



not modelled 45.8 18 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Lrp/AsnC-like transcriptional regulator N-terminal domain
37c3f6wE_



not modelled 44.3 15 PDB header:dna binding protein
Chain: E: PDB Molecule:xre-family like protein;
PDBTitle: xre-family like protein from pseudomonas syringae pv. tomato str.2 dc3000
38d2p12a1



not modelled 44.1 12 Fold:FomD barrel-like
Superfamily:FomD-like
Family:FomD-like
39d1y9qa1



not modelled 43.5 7 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Probable transcriptional regulator VC1968, N-terminal domain
40c2o38A_



not modelled 43.5 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein;
PDBTitle: putative xre family transcriptional regulator
41d2o38a1



not modelled 43.5 16 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:NE1354
42c2kpjA_



not modelled 43.2 18 PDB header:transcription regulator
Chain: A: PDB Molecule:sos-response transcriptional repressor, lexa;
PDBTitle: solution structure of protein sos-response transcriptional2 repressor, lexa from eubacterium rectale. northeast3 structural genomics consortium target err9a
43c3mkzU_



not modelled 43.1 6 PDB header:dna-binding protein/dna
Chain: U: PDB Molecule:protein sopb;
PDBTitle: structure of sopb(155-272)-18mer complex, p21 form
44c1vkoA_



not modelled 42.2 21 PDB header:isomerase
Chain: A: PDB Molecule:inositol-3-phosphate synthase;
PDBTitle: crystal structure of inositol-3-phosphate synthase (ce21227) from2 caenorhabditis elegans at 2.30 a resolution
45c3b7hA_



not modelled 40.8 7 PDB header:structural protein
Chain: A: PDB Molecule:prophage lp1 protein 11;
PDBTitle: crystal structure of the prophage lp1 protein 11
46c2dbbA_



not modelled 40.4 24 PDB header:transcriptional regulator
Chain: A: PDB Molecule:putative hth-type transcriptional regulator ph0061;
PDBTitle: crystal structure of ph0061
47c3lsgD_



not modelled 39.8 9 PDB header:transcription regulator
Chain: D: PDB Molecule:two-component response regulator yesn;
PDBTitle: the crystal structure of the c-terminal domain of the two-2 component response regulator yesn from fusobacterium3 nucleatum subsp. nucleatum atcc 25586
48d1rp3a1



not modelled 39.0 23 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family:Sigma3 domain
49c2ebyA_



not modelled 38.9 16 PDB header:transcription
Chain: A: PDB Molecule:putative hth-type transcriptional regulator ybaq;
PDBTitle: crystal structure of a hypothetical protein from e. coli
50c3f52A_



not modelled 38.4 20 PDB header:transcription activator
Chain: A: PDB Molecule:clp gene regulator (clgr);
PDBTitle: crystal structure of the clp gene regulator clgr from c. glutamicum
51d1e6yb1



not modelled 35.9 27 Fold:Methyl-coenzyme M reductase alpha and beta chain C-terminal domain
Superfamily:Methyl-coenzyme M reductase alpha and beta chain C-terminal domain
Family:Methyl-coenzyme M reductase alpha and beta chain C-terminal domain
52c3oioA_



not modelled 35.9 15 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator (arac-type dna-binding domain-
PDBTitle: crystal structure of transcriptional regulator (arac-type dna-binding2 domain-containing proteins) from chromobacterium violaceum
53c3k2zA_



not modelled 35.5 18 PDB header:hydrolase
Chain: A: PDB Molecule:lexa repressor;
PDBTitle: crystal structure of a lexa protein from thermotoga maritima
54c1r71B_



not modelled 35.2 6 PDB header:transcription/dna
Chain: B: PDB Molecule:transcriptional repressor protein korb;
PDBTitle: crystal structure of the dna binding domain of korb in2 complex with the operator dna
55d1ttya_



not modelled 35.2 10 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family:Sigma4 domain
56c2e1cA_



not modelled 34.3 15 PDB header:transcription/dna
Chain: A: PDB Molecule:putative hth-type transcriptional regulator ph1519;
PDBTitle: structure of putative hth-type transcriptional regulator ph1519/dna2 complex
57c3exmA_



not modelled 33.4 11 PDB header:hydrolase
Chain: A: PDB Molecule:phosphatase sc4828;
PDBTitle: crystal structure of the phosphatase sc4828 with the non-hydrolyzable2 nucleotide gpcp
58d2r1jl1



not modelled 32.5 13 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Phage repressors
59d3ygsp_



not modelled 32.4 13 Fold:DEATH domain
Superfamily:DEATH domain
Family:Caspase recruitment domain, CARD
60c2p6tH_



not modelled 30.8 12 PDB header:transcription
Chain: H: PDB Molecule:transcriptional regulator, lrp/asnc family;
PDBTitle: crystal structure of transcriptional regulator nmb0573 and l-leucine2 complex from neisseria meningitidis
61c2q9lA_



not modelled 30.0 21 PDB header:hydrolase
Chain: A: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of imazg from vibrio dat 722: ctag-imazg (p43212)
62c2vbzA_



not modelled 28.8 24 PDB header:dna-binding protein
Chain: A: PDB Molecule:transcriptional regulatory protein;
PDBTitle: feast or famine regulatory protein (rv3291c)from m.2 tuberculosis complexed with l-tryptophan
63d1e6vb1



not modelled 28.3 22 Fold:Methyl-coenzyme M reductase alpha and beta chain C-terminal domain
Superfamily:Methyl-coenzyme M reductase alpha and beta chain C-terminal domain
Family:Methyl-coenzyme M reductase alpha and beta chain C-terminal domain
64d1llib_



not modelled 27.3 12 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Phage repressors
65d2b5aa1



not modelled 26.5 16 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:SinR domain-like
66d2f2ea1



not modelled 26.5 28 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:HxlR-like
67d1z0xa1



not modelled 26.3 17 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:Tetracyclin repressor-like, N-terminal domain
68d1ui5a1



not modelled 26.3 20 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:Tetracyclin repressor-like, N-terminal domain
69d2vcha1



not modelled 25.9 6 Fold:UDP-Glycosyltransferase/glycogen phosphorylase
Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase
Family:UDPGT-like
70d1r71a_



not modelled 25.7 6 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:KorB DNA-binding domain-like
Family:KorB DNA-binding domain-like
71c3hugJ_



not modelled 25.7 10 PDB header:transcription/membrane protein
Chain: J: PDB Molecule:probable conserved membrane protein;
PDBTitle: crystal structure of mycobacterium tuberculosis anti-sigma factor rsla2 in complex with -35 promoter binding domain of sigl
72c3kxaD_



not modelled 25.5 15 PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of ngo0477 from neisseria gonorrhoeae
73d1or7a1



not modelled 25.3 25 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family:Sigma4 domain
74d2jn6a1



not modelled 25.1 20 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:Cgl2762-like
75c3clcC_



not modelled 25.0 4 PDB header:transcription regulator/dna
Chain: C: PDB Molecule:regulatory protein;
PDBTitle: crystal structure of the restriction-modification controller protein2 c.esp1396i tetramer in complex with its natural 35 base-pair operator
76c3bhqB_



not modelled 24.8 10 PDB header:transcription
Chain: B: PDB Molecule:transcriptional regulator;
PDBTitle: crystal structure of a putative tetr-family transcriptional regulator2 (mlr_4833) from mesorhizobium loti maff303099 at 1.54 a resolution
77c1nvpD_



not modelled 24.8 9 PDB header:transcription/dna
Chain: D: PDB Molecule:transcription initiation factor iia gamma chain;
PDBTitle: human tfiia/tbp/dna complex
78d1adra_



not modelled 24.6 15 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Phage repressors
79c3k0lA_



not modelled 24.6 15 PDB header:transcription regulator
Chain: A: PDB Molecule:repressor protein;
PDBTitle: crystal structure of putative marr family transcriptional2 regulator from acinetobacter sp. adp
80c3mlfC_



not modelled 24.3 12 PDB header:transcription regulator
Chain: C: PDB Molecule:transcriptional regulator;
PDBTitle: putative transcriptional regulator from staphylococcus aureus.
81d1kl7a_



not modelled 23.8 16 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
82c1e6yE_



not modelled 23.7 29 PDB header:oxidoreductase
Chain: E: PDB Molecule:methyl-coenzyme m reductase i beta subunit;
PDBTitle: methyl-coenzyme m reductase from methanosarcina barkeri
83d1nh2d1



not modelled 23.7 12 Fold:Transcription factor IIA (TFIIA), alpha-helical domain
Superfamily:Transcription factor IIA (TFIIA), alpha-helical domain
Family:Transcription factor IIA (TFIIA), alpha-helical domain
84d1lmb3_



not modelled 23.6 11 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Phage repressors
85c2cfxD_



not modelled 23.6 9 PDB header:transcription
Chain: D: PDB Molecule:hth-type transcriptional regulator lrpc;
PDBTitle: structure of b.subtilis lrpc
86c2k9sA_



not modelled 23.4 10 PDB header:transcription
Chain: A: PDB Molecule:arabinose operon regulatory protein;
PDBTitle: solution structure of dna binding domain of e. coli arac
87c2ia0A_



not modelled 23.1 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative hth-type transcriptional regulator pf0864;
PDBTitle: transcriptional regulatory protein pf0864 from pyrococcus furiosus a2 member of the asnc family (pf0864)
88c2gqqB_



not modelled 22.9 9 PDB header:transcription
Chain: B: PDB Molecule:leucine-responsive regulatory protein;
PDBTitle: crystal structure of e. coli leucine-responsive regulatory protein2 (lrp)
89c1i1gA_



not modelled 22.8 18 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulator lrpa;
PDBTitle: crystal structure of the lrp-like transcriptional regulator from the2 archaeon pyrococcus furiosus
90c2p8tA_



not modelled 22.3 26 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein ph0730;
PDBTitle: hypothetical protein ph0730 from pyrococcus horikoshii ot3
91d2h5na1



not modelled 22.2 26 Fold:TerB-like
Superfamily:TerB-like
Family:PG1108-like
92c3mzyA_



not modelled 22.2 25 PDB header:rna binding protein
Chain: A: PDB Molecule:rna polymerase sigma-h factor;
PDBTitle: the crystal structure of the rna polymerase sigma-h factor from2 fusobacterium nucleatum to 2.5a
93d1in4a1



not modelled 22.1 19 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Helicase DNA-binding domain
94c3oouA_



not modelled 22.1 10 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:lin2118 protein;
PDBTitle: the structure of a protein with unkown function from listeria innocua
95d1sq8a_



not modelled 22.0 20 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Phage repressors
96c2nz7A_



not modelled 21.9 8 PDB header:apoptosis
Chain: A: PDB Molecule:caspase recruitment domain-containing protein 4;
PDBTitle: crystal structure analysis of caspase-recruitment domain2 (card) of nod1
97d1b0na2



not modelled 21.8 9 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:SinR domain-like
98c1bl0A_



not modelled 21.7 6 PDB header:transcription/dna
Chain: A: PDB Molecule:protein (multiple antibiotic resistance protein);
PDBTitle: multiple antibiotic resistance protein (mara)/dna complex
99d1r69a_



not modelled 21.7 17 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Phage repressors
100c3katA_



not modelled 21.6 7 PDB header:apoptosis
Chain: A: PDB Molecule:nacht, lrr and pyd domains-containing protein 1;
PDBTitle: crystal structure of the card domain of the human nlrp12 protein, northeast structural genomics consortium target3 hr3486e
101c3b6aC_



not modelled 21.5 15 PDB header:transcription
Chain: C: PDB Molecule:actr protein;
PDBTitle: crystal structure of the streptomyces coelicolor tetr2 family protein actr in complex with actinorhodin
102d2fq4a1



not modelled 21.4 9 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:Tetracyclin repressor-like, N-terminal domain
103c2b1wA_



not modelled 20.9 8 PDB header:apoptosis
Chain: A: PDB Molecule:caspase recruitment domain protein 4;
PDBTitle: solution structure of the nod1 caspase activating and recruitment2 domain
104d1uxca_



not modelled 20.3 8 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:GalR/LacI-like bacterial regulator
105c1zljE_



not modelled 20.3 20 PDB header:transcription
Chain: E: PDB Molecule:dormancy survival regulator;
PDBTitle: crystal structure of the mycobacterium tuberculosis hypoxic2 response regulator dosr c-terminal domain
106c4a5mH_



not modelled 20.2 19 PDB header:transcription
Chain: H: PDB Molecule:uncharacterized hth-type transcriptional regulator yybr;
PDBTitle: redox regulator hypr in its oxidized form
107d1ixrc1



not modelled 20.1 17 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Helicase DNA-binding domain
108c3t76A_



not modelled 20.1 8 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator vanug;
PDBTitle: crystal structure of transcriptional regulator vanug, form ii

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0