Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	I	P	K	L	Q	A	Y	A	L	P	E	S	H	D	I	P	Q	N	K	V	D	W	A	F	E	P	Q	R	A	A	L	L	I	H	D	M	Q	D	Y	F	V	S	F	W	G	E	N	C	P	M	M	E	Q	V	I	A	N	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	A	L	R	D	Y	C	K	Q	H	N	I	P	V	Y	Y	T	A	Q	P	K	E	Q	S	D	E	D	R	A	L	L	N	D	M	W	G	P	G	L	T	R	S	P	E	Q	Q	K	V	V	D	R	L	T	P	D	A	D	D	T	V
Secondary structure
SS confidence
Disorder																										?							?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	V	K	W	R	Y	S	A	F	H	R	S	P	L	E	Q	M	L	K	E	S	G	R	N	Q	L	I	I	T	G	V	Y	A	H	I	G	C	M	T	T	A	T	D	A	F	M	R	D	I	K	P	F	M	V	A	D	A	L	A	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		F	S	R	D	E	H	L	M	S	L	K	Y	V	A	G	R	S	G	R	V	V	M	T	E	E	L	L	P	A	P	I	P	A	S	K	A	A	L	R	E	V	I	L	P	L	L	D	E	S	D	E	P	F	D	D	D	N	L	I	D
Secondary structure
SS confidence
Disorder																																	?	?	?	?	?	?							?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.
Sequence		Y	G	L	D	S	V	R	M	M	A	L	A	A	R	W	R	K	V	H	G	D	I	D	F	V	M	L	A	K	N	P	T	I	D	A	W	W	K	L	L	S	R	E	V	K
Secondary structure
SS confidence
Disorder																																											?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2fq1 chain A Region: 5 - 283 Aligned: 279 Modelled: 279 Confidence: 100.0% Identity: 100% PDB header:hydrolase Chain: A: PDB Molecule:isochorismatase; PDBTitle: crystal structure of the two-domain non-ribosomal peptide synthetase2 entb containing isochorismate lyase and aryl-carrier protein domains Phyre2 PDB 1nf9 chain A Region: 3 - 208 Aligned: 204 Modelled: 206 Confidence: 100.0% Identity: 47% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 1nba chain A Region: 29 - 208 Aligned: 180 Modelled: 180 Confidence: 100.0% Identity: 23% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 3irv chain A Region: 17 - 213 Aligned: 197 Modelled: 197 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:cysteine hydrolase; PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a Phyre2 PDB 3ot4 chain F Region: 26 - 207 Aligned: 181 Modelled: 182 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: F: PDB Molecule:putative isochorismatase; PDBTitle: structure and catalytic mechanism of bordetella bronchiseptica nicf Phyre2 PDB 1j2r chain A Region: 24 - 209 Aligned: 185 Modelled: 186 Confidence: 100.0% Identity: 21% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 3kl2 chain K Region: 26 - 209 Aligned: 184 Modelled: 184 Confidence: 100.0% Identity: 20% PDB header:structural genomics, unknown function Chain: K: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis Phyre2 PDB 3oqp chain A Region: 30 - 210 Aligned: 169 Modelled: 181 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution Phyre2 PDB 3oqp chain B Region: 30 - 210 Aligned: 169 Modelled: 181 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: B: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution Phyre2 PDB 3hu5 chain B Region: 29 - 206 Aligned: 178 Modelled: 178 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: B: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein from desulfovibrio2 vulgaris subsp. vulgaris str. hildenborough Phyre2 PDB 3mcw chain A Region: 22 - 216 Aligned: 183 Modelled: 195 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of an a putative hydrolase of the isochorismatase2 family (cv_1320) from chromobacterium violaceum atcc 12472 at 1.06 a3 resolution Phyre2 PDB 3hb7 chain G Region: 29 - 211 Aligned: 181 Modelled: 183 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: G: PDB Molecule:isochorismatase hydrolase; PDBTitle: the crystal structure of an isochorismatase-like hydrolase from2 alkaliphilus metalliredigens to 2.3a Phyre2 PDB 3eef chain A Region: 29 - 208 Aligned: 173 Modelled: 179 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein; PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum Phyre2 PDB 1im5 chain A Region: 30 - 201 Aligned: 172 Modelled: 172 Confidence: 100.0% Identity: 20% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 3r2j chain C Region: 25 - 209 Aligned: 183 Modelled: 185 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta-hydrolase-like protein; PDBTitle: crystal structure of pnc1 from l. infantum in complex with nicotinate Phyre2 PDB 3lqy chain A Region: 24 - 208 Aligned: 172 Modelled: 185 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase hydrolase; PDBTitle: crystal structure of putative isochorismatase hydrolase from2 oleispira antarctica Phyre2 PDB 3o93 chain A Region: 30 - 206 Aligned: 176 Modelled: 177 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: high resolution crystal structures of streptococcus pneumoniae2 nicotinamidase with trapped intermediates provide insights into3 catalytic mechanism and inhibition by aldehydes Phyre2 PDB 2wta chain A Region: 24 - 209 Aligned: 182 Modelled: 186 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: acinetobacter baumanii nicotinamidase pyrazinamidease Phyre2 PDB 3gbc chain A Region: 32 - 203 Aligned: 172 Modelled: 172 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:pyrazinamidase/nicotinamidas pnca; PDBTitle: determination of the crystal structure of the pyrazinamidase from2 m.tuberculosis : a structure-function analysis for prediction3 resistance to pyrazinamide Phyre2 PDB 1yac chain A Region: 21 - 221 Aligned: 179 Modelled: 181 Confidence: 100.0% Identity: 20% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 1 c2fq1A_ 2 d1nf9a_ 3 d1nbaa_ 4 c3irvA_ 5 c3ot4F_ 6 d1j2ra_ 7 c3kl2K_ 8 c3oqpA_ 9 c3oqpB_ 10 c3hu5B_ 11 c3mcwA_ 12 c3hb7G_ 13 c3eefA_ 14 d1im5a_ 15 c3r2jC_ 16 c3lqyA_ 17 c3o93A_ 18 c2wtaA_ 19 c3gbcA_ 20 d1yaca_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2fq1A_ 100.0 100 PDB header:hydrolase Chain: A: PDB Molecule:isochorismatase; PDBTitle: crystal structure of the two-domain non-ribosomal peptide synthetase2 entb containing isochorismate lyase and aryl-carrier protein domains 2 d1nf9a_ 100.0 47 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 3 d1nbaa_ 100.0 23 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 4 c3irvA_ 100.0 26 PDB header:hydrolase Chain: A: PDB Molecule:cysteine hydrolase; PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a 5 c3ot4F_ 100.0 19 PDB header:hydrolase Chain: F: PDB Molecule:putative isochorismatase; PDBTitle: structure and catalytic mechanism of bordetella bronchiseptica nicf 6 d1j2ra_ 100.0 21 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 7 c3kl2K_ 100.0 20 PDB header:structural genomics, unknown function Chain: K: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis 8 c3oqpA_ 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution 9 c3oqpB_ 100.0 23 PDB header:hydrolase Chain: B: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution 10 c3hu5B_ 100.0 24 PDB header:hydrolase Chain: B: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein from desulfovibrio2 vulgaris subsp. vulgaris str. hildenborough 11 c3mcwA_ 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of an a putative hydrolase of the isochorismatase2 family (cv_1320) from chromobacterium violaceum atcc 12472 at 1.06 a3 resolution 12 c3hb7G_ 100.0 21 PDB header:hydrolase Chain: G: PDB Molecule:isochorismatase hydrolase; PDBTitle: the crystal structure of an isochorismatase-like hydrolase from2 alkaliphilus metalliredigens to 2.3a 13 c3eefA_ 100.0 23 PDB header:hydrolase Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein; PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum 14 d1im5a_ 100.0 20 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 15 c3r2jC_ 100.0 17 PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta-hydrolase-like protein; PDBTitle: crystal structure of pnc1 from l. infantum in complex with nicotinate 16 c3lqyA_ 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase hydrolase; PDBTitle: crystal structure of putative isochorismatase hydrolase from2 oleispira antarctica 17 c3o93A_ 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: high resolution crystal structures of streptococcus pneumoniae2 nicotinamidase with trapped intermediates provide insights into3 catalytic mechanism and inhibition by aldehydes 18 c2wtaA_ 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: acinetobacter baumanii nicotinamidase pyrazinamidease 19 c3gbcA_ 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:pyrazinamidase/nicotinamidas pnca; PDBTitle: determination of the crystal structure of the pyrazinamidase from2 m.tuberculosis : a structure-function analysis for prediction3 resistance to pyrazinamide 20 d1yaca_ 100.0 20 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 21 c2a67C_ not modelled 100.0 20 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein 22 c2b34C_ not modelled 100.0 21 PDB header:hydrolase Chain: C: PDB Molecule:mar1 ribonuclease; PDBTitle: structure of mar1 ribonuclease from caenorhabditis elegans 23 c1yzvA_ not modelled 100.0 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: hypothetical protein from trypanosoma cruzi 24 d1x9ga_ not modelled 100.0 16 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 25 c2h0rD_ not modelled 100.0 18 PDB header:hydrolase Chain: D: PDB Molecule:nicotinamidase; PDBTitle: structure of the yeast nicotinamidase pnc1p 26 c2cq8A_ not modelled 99.6 19 PDB header:oxidoreductase Chain: A: PDB Molecule:10-formyltetrahydrofolate dehydrogenase; PDBTitle: solution structure of rsgi ruh-033, a pp-binding domain of2 10-fthfdh from human cdna 27 c2jgpA_ not modelled 99.6 23 PDB header:ligase Chain: A: PDB Molecule:tyrocidine synthetase 3; PDBTitle: structure of the tycc5-6 pcp-c bidomain of the tyrocidine2 synthetase tycc 28 c2roqA_ not modelled 99.6 19 PDB header:transferase Chain: A: PDB Molecule:enterobactin synthetase component f; PDBTitle: solution structure of the thiolation-thioesterase di-domain2 of enterobactin synthetase component f 29 c2vsqA_ not modelled 99.6 18 PDB header:ligase Chain: A: PDB Molecule:surfactin synthetase subunit 3; PDBTitle: structure of surfactin a synthetase c (srfa-c), a2 nonribosomal peptide synthetase termination module 30 d2gdwa1 not modelled 99.5 27 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Peptidyl carrier domain 31 c2ju2A_ not modelled 99.5 14 PDB header:transferase Chain: A: PDB Molecule:erythronolide synthase; PDBTitle: minimized mean solution structure of the acyl carrier2 protein domain from module 2 of 6-deoxyerythronolide b3 synthase (debs) 32 c2liuA_ not modelled 99.5 17 PDB header:transferase Chain: A: PDB Molecule:cura; PDBTitle: nmr structure of holo-acpi domain from cura module from lyngbya2 majuscula 33 c2afdA_ not modelled 99.5 22 PDB header:ligand binding protein Chain: A: PDB Molecule:protein asl1650; PDBTitle: solution structure of asl1650, an acyl carrier protein from anabaena2 sp. pcc 7120 with a variant phosphopantetheinylation-site sequence 34 c2kr5A_ not modelled 99.3 21 PDB header:transport protein Chain: A: PDB Molecule:aflatoxin biosynthesis polyketide synthase; PDBTitle: solution structure of an acyl carrier protein domain from fungal type2 i polyketide synthase 35 d2af8a_ not modelled 99.3 22 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 36 d1or5a_ not modelled 99.3 15 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 37 c2ehtA_ not modelled 99.3 19 PDB header:lipid transport Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: crystal structure of acyl carrier protein from aquifex aeolicus (form2 2) 38 d1nq4a_ not modelled 99.3 17 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 39 d1vkua_ not modelled 99.3 10 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 40 d1klpa_ not modelled 99.3 21 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 41 d1t8ka_ not modelled 99.2 17 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 42 c1x3oA_ not modelled 99.2 16 PDB header:lipid transport Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: crystal structure of the acyl carrier protein from thermus2 thermophilus hb8 43 c2fq2A_ not modelled 99.2 17 PDB header:lipid transport Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: solution structure of minor conformation of holo-acyl2 carrier protein from malaria parasite plasmodium falciparum 44 c2qnwA_ not modelled 99.2 15 PDB header:signaling protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: toxoplasma gondii apicoplast-targeted acyl carrier protein 45 c2cgqA_ not modelled 99.2 17 PDB header:protein transport Chain: A: PDB Molecule:acyl carrier protein acpa; PDBTitle: a putative acyl carrier protein(rv0033) from mycobacterium2 tuberculosis 46 c2l3vA_ not modelled 99.2 15 PDB header:lipid binding protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: nmr structure of acyl carrier protein from brucella melitensis 47 d1f80d_ not modelled 99.2 9 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 48 c2cnrA_ not modelled 99.1 17 PDB header:lipid transport Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: structural studies on the interaction of scfas acp with2 acps 49 d2pnga1 not modelled 99.1 15 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 50 c3ejbC_ not modelled 99.1 17 PDB header:oxidoreductase/lipid transport Chain: C: PDB Molecule:acyl carrier protein; PDBTitle: crystal structure of p450bioi in complex with tetradecanoic2 acid ligated acyl carrier protein 51 c2fvfA_ not modelled 99.1 12 PDB header:biosynthetic protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: structure of 10:0-acp (protein with docked fatty acid) 52 c2jq4A_ not modelled 99.1 20 PDB header:structural genomics Chain: A: PDB Molecule:hypothetical protein atu2571; PDBTitle: complete resonance assignments and solution structure2 calculation of atc2521 (nesg id: att6) from agrobacterium3 tumefaciens 53 d2jq4a1 not modelled 99.1 20 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 54 c2l9fA_ not modelled 99.0 11 PDB header:transferase Chain: A: PDB Molecule:cale8; PDBTitle: nmr solution structure of meacp 55 c2dnwA_ not modelled 99.0 11 PDB header:transport protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: solution structure of rsgi ruh-059, an acp domain of acyl2 carrier protein, mitochondrial [precursor] from human cdna 56 c2kciA_ not modelled 99.0 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative acyl carrier protein; PDBTitle: solution nmr structure of gmet_2339 from geobacter2 metallireducens. northeast structural genomics consortium3 target gmr141 57 c2kwlA_ not modelled 99.0 18 PDB header:lipid binding protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: solution structure of acyl carrier protein from borrelia burgdorferi 58 c2l4bA_ not modelled 99.0 22 PDB header:transferase Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: solution structure of a putative acyl carrier protein from anaplasma2 phagocytophilum. seattle structural genomics center for infectious3 disease target anpha.01018.a 59 d1dv5a_ not modelled 98.9 19 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:apo-D-alanyl carrier protein 60 c3lmoA_ not modelled 98.7 15 PDB header:transferase Chain: A: PDB Molecule:specialized acyl carrier protein; PDBTitle: crystal structure of specialized acyl carrier protein2 (rpa2022) from rhodopseudomonas palustris, northeast3 structural genomics consortium target rpr324 61 c3ce7A_ not modelled 98.6 10 PDB header:biosynthetic protein Chain: A: PDB Molecule:specific mitochodrial acyl carrier protein; PDBTitle: crystal structure of toxoplasma specific mitochodrial acyl2 carrier protein, 59.m03510 62 c2vkzC_ not modelled 95.4 5 PDB header:transferase Chain: C: PDB Molecule:fatty acid synthase subunit alpha; PDBTitle: structure of the cerulenin-inhibited fungal fatty acid2 synthase type i multienzyme complex 63 c2uv8C_ not modelled 94.7 5 PDB header:transferase Chain: C: PDB Molecule:fatty acid synthase subunit alpha (fas2); PDBTitle: crystal structure of yeast fatty acid synthase with stalled2 acyl carrier protein at 3.1 angstrom resolution 64 c3s8mA_ not modelled 92.9 19 PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-acp reductase; PDBTitle: the crystal structure of fabv 65 c2uv9B_ not modelled 89.1 4 PDB header:transferase Chain: B: PDB Molecule:fatty acid synthase alpha subunits; PDBTitle: crystal structure of fatty acid synthase from thermomyces2 lanuginosus at 3.1 angstrom resolution. this file contains3 the alpha subunits of the fatty acid synthase. the entire4 crystal structure consists of one heterododecameric fatty5 acid synthase and is described in remark 400 66 d1xp8a1 not modelled 77.0 6 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 67 d1cmwa2 not modelled 76.6 17 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 68 d1f2da_ not modelled 71.9 9 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 69 c1x1qA_ not modelled 66.7 13 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase beta chain; PDBTitle: crystal structure of tryptophan synthase beta chain from thermus2 thermophilus hb8 70 d2zdra2 not modelled 65.8 11 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 71 c3bgwD_ not modelled 63.6 14 PDB header:replication Chain: D: PDB Molecule:dnab-like replicative helicase; PDBTitle: the structure of a dnab-like replicative helicase and its interactions2 with primase 72 c1xuzA_ not modelled 62.9 10 PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol 73 c2iusB_ not modelled 62.6 15 PDB header:membrane protein Chain: B: PDB Molecule:dna translocase ftsk; PDBTitle: e. coli ftsk motor domain 74 c2iutA_ not modelled 59.0 15 PDB header:membrane protein Chain: A: PDB Molecule:dna translocase ftsk; PDBTitle: p. aeruginosa ftsk motor domain, dimeric 75 c2iuuE_ not modelled 58.6 15 PDB header:membrane protein Chain: E: PDB Molecule:dna translocase ftsk; PDBTitle: p. aeruginosa ftsk motor domain, hexamer 76 c2recB_ not modelled 58.0 11 PDB header:helicase PDB COMPND: 77 d1ubea1 not modelled 56.7 6 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 78 d1vp8a_ not modelled 56.2 19 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:MTH1675-like 79 c3g8rA_ not modelled 55.7 12 PDB header:biosynthetic protein Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e; PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472 80 d1vlia2 not modelled 55.2 14 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 81 c2vyeA_ not modelled 53.5 13 PDB header:hydrolase Chain: A: PDB Molecule:replicative dna helicase; PDBTitle: crystal structure of the dnac-ssdna complex 82 c1xp8A_ not modelled 53.0 6 PDB header:dna binding protein Chain: A: PDB Molecule:reca protein; PDBTitle: "deinococcus radiodurans reca in complex with atp-gamma-s" 83 c3cbwA_ not modelled 48.4 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:ydht protein; PDBTitle: crystal structure of the ydht protein from bacillus subtilis 84 c2ihnA_ not modelled 45.9 7 PDB header:hydrolase/dna Chain: A: PDB Molecule:ribonuclease h; PDBTitle: co-crystal of bacteriophage t4 rnase h with a fork dna2 substrate 85 d1xu9a_ not modelled 44.7 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 86 d2ae2a_ not modelled 44.6 14 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 87 c3nugA_ not modelled 44.2 8 PDB header:oxidoreductase Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase; PDBTitle: crystal structure of wild type tetrameric pyridoxal 4-dehydrogenase2 from mesorhizobium loti 88 d1tfra2 not modelled 42.3 7 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 89 c3ijrF_ not modelled 42.2 17 PDB header:oxidoreductase Chain: F: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family; PDBTitle: 2.05 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor' in complex3 with nad+ 90 d1ae1a_ not modelled 41.8 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 91 d1gz6a_ not modelled 41.7 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 92 d1xsea_ not modelled 41.2 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 93 c2cvhB_ not modelled 40.4 19 PDB header:dna binding protein Chain: B: PDB Molecule:dna repair and recombination protein radb; PDBTitle: crystal structure of the radb recombinase 94 d2a4ka1 not modelled 40.3 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 95 c2pd6D_ not modelled 40.2 11 PDB header:oxidoreductase Chain: D: PDB Molecule:estradiol 17-beta-dehydrogenase 8; PDBTitle: structure of human hydroxysteroid dehydrogenase type 8, hsd17b8 96 c3ai3A_ not modelled 40.2 17 PDB header:oxidoreductase Chain: A: PDB Molecule:nadph-sorbose reductase; PDBTitle: the crystal structure of l-sorbose reductase from gluconobacter2 frateurii complexed with nadph and l-sorbose 97 c1vliA_ not modelled 39.5 12 PDB header:biosynthetic protein Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse; PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution 98 d1mo6a1 not modelled 37.2 6 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 99 d1e0ta2 not modelled 37.2 16 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 100 c3bh0A_ not modelled 37.0 13 PDB header:replication Chain: A: PDB Molecule:dnab-like replicative helicase; PDBTitle: atpase domain of g40p 101 c2nwqA_ not modelled 36.8 15 PDB header:oxidoreductase Chain: A: PDB Molecule:probable short-chain dehydrogenase; PDBTitle: short chain dehydrogenase from pseudomonas aeruginosa 102 c2y8kA_ not modelled 35.6 9 PDB header:hydrolase Chain: A: PDB Molecule:carbohydrate binding family 6; PDBTitle: structure of ctgh5-cbm6, an arabinoxylan-specific xylanase. 103 c2nm0B_ not modelled 35.6 19 PDB header:oxidoreductase Chain: B: PDB Molecule:probable 3-oxacyl-(acyl-carrier-protein) reductase; PDBTitle: crystal structure of sco1815: a beta-ketoacyl-acyl carrier protein2 reductase from streptomyces coelicolor a3(2) 104 c3ldaA_ not modelled 35.6 22 PDB header:dna binding protein Chain: A: PDB Molecule:dna repair protein rad51; PDBTitle: yeast rad51 h352y filament interface mutant 105 c3toxG_ not modelled 34.3 21 PDB header:oxidoreductase Chain: G: PDB Molecule:short chain dehydrogenase; PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021 106 c3n7tA_ not modelled 33.0 13 PDB header:protein binding Chain: A: PDB Molecule:macrophage binding protein; PDBTitle: crystal structure of a macrophage binding protein from coccidioides2 immitis 107 d1pkla2 not modelled 32.6 24 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 108 c2zroA_ not modelled 32.1 7 PDB header:hydrolase Chain: A: PDB Molecule:protein reca; PDBTitle: msreca adp form iv 109 c3o26A_ not modelled 31.3 14 PDB header:oxidoreductase Chain: A: PDB Molecule:salutaridine reductase; PDBTitle: the structure of salutaridine reductase from papaver somniferum. 110 d1wdea_ not modelled 31.3 15 Fold:Tetrapyrrole methylase Superfamily:Tetrapyrrole methylase Family:Tetrapyrrole methylase 111 c3enoB_ not modelled 30.1 21 PDB header:hydrolase/unknown function Chain: B: PDB Molecule:putative o-sialoglycoprotein endopeptidase; PDBTitle: crystal structure of pyrococcus furiosus pcc1 in complex2 with thermoplasma acidophilum kae1 112 d1a3xa2 not modelled 30.1 21 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 113 c2dflA_ not modelled 29.9 15 PDB header:recombination Chain: A: PDB Molecule:dna repair and recombination protein rada; PDBTitle: crystal structure of left-handed rada filament 114 c2b4qB_ not modelled 28.8 12 PDB header:oxidoreductase Chain: B: PDB Molecule:rhamnolipids biosynthesis 3-oxoacyl-[acyl- PDBTitle: pseudomonas aeruginosa rhlg/nadp active-site complex 115 c2amwA_ not modelled 28.4 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ne2163; PDBTitle: solution nmr structure of protein ne2163 from nitrosomonas europaea.2 northeast structural genomics consortium target net1. 116 c2lkiA_ not modelled 28.4 13 PDB header:lipid transport Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: solution nmr structure of holo acyl carrier protein ne2163 from2 nitrosomonas europaea. northeast structural genomics consortium3 target net1. 117 d1o4wa_ not modelled 28.2 37 Fold:PIN domain-like Superfamily:PIN domain-like Family:PIN domain 118 d1qopb_ not modelled 28.2 13 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 119 c3sjuA_ not modelled 28.2 15 PDB header:oxidoreductase Chain: A: PDB Molecule:keto reductase; PDBTitle: hedamycin polyketide ketoreductase bound to nadph 120 d2pd4a1 not modelled 27.8 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0