Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	P	S	Q	S	P	A	I	F	T	V	S	R	L	N	Q	T	V	R	L	L	L	E	H	E	M	G	Q	V	W	I	S	G	E	I	S	N	F	T	Q	P	A	S	G	H	W	Y	F	T	L	K	D	D	T	A	Q	V	R	C
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?																														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	M	F	R	N	S	N	R	R	V	T	F	R	P	Q	H	G	Q	Q	V	L	V	R	A	N	I	T	L	Y	E	P	R	G	D	Y	Q	I	I	V	E	S	M	Q	P	A	G	E	G	L	L	Q	Q	K	Y	E	Q	L	K	A	K
Secondary structure
SS confidence
Disorder								?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	Q	A	E	G	L	F	D	Q	Q	Y	K	K	P	L	P	S	P	A	H	C	V	G	V	I	T	S	K	T	G	A	A	L	H	D	I	L	H	V	L	K	R	R	D	P	S	L	P	V	I	I	Y	P	A	A	V	Q	G	D	D
Secondary structure
SS confidence
Disorder						?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	P	G	Q	I	V	R	A	I	E	L	A	N	Q	R	N	E	C	D	V	L	I	V	G	R	G	G	G	S	L	E	D	L	W	S	F	N	D	E	R	V	A	R	A	I	F	T	S	R	I	P	V	V	S	A	V	G	H	E	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		D	V	T	I	A	D	F	V	A	D	L	R	A	P	T	P	S	A	A	A	E	V	V	S	R	N	Q	Q	E	L	L	R	Q	V	Q	S	T	R	Q	R	L	E	M	A	M	D	Y	Y	L	A	N	R	T	R	R	F	T	Q	I	H
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		H	R	L	Q	Q	Q	H	P	Q	L	R	L	A	R	Q	Q	T	M	L	E	R	L	Q	K	R	M	S	F	A	L	E	N	Q	L	K	R	T	G	Q	Q	Q	Q	R	L	T	Q	R	L	N	Q	Q	N	P	Q	P	K	I	H	R	A
Secondary structure
SS confidence
Disorder							?																																												?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		Q	T	R	I	Q	Q	L	E	Y	R	L	A	E	T	L	R	A	Q	L	S	A	T	R	E	R	F	G	N	A	V	T	H	L	E	A	V	S	P	L	S	T	L	A	R	G	Y	S	V	T	T	A	T	D	G	N	V	L	K	K	V
Secondary structure
SS confidence
Disorder																																																							?			?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.
Sequence		K	Q	V	K	A	G	E	M	L	T	T	R	L	E	D	G	W	I	E	S	E	V	K	N	I	Q	P	V	K	K	S	R	K	K	V	H
Secondary structure
SS confidence
Disorder				?	?	?																				?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3kf6 chain A Region: 27 - 124 Aligned: 95 Modelled: 98 Confidence: 96.8% Identity: 17% PDB header:structural protein Chain: A: PDB Molecule:protein stn1; PDBTitle: crystal structure of s. pombe stn1-ten1 complex Phyre2 PDB 1z9f chain A Region: 27 - 104 Aligned: 78 Modelled: 78 Confidence: 96.4% Identity: 14% PDB header:dna binding protein Chain: A: PDB Molecule:single-strand binding protein; PDBTitle: crystal structure of single stranded dna-binding protein (tm0604) from2 thermotoga maritima at 2.60 a resolution Phyre2 PDB 3bfj chain K Region: 139 - 234 Aligned: 83 Modelled: 96 Confidence: 96.3% Identity: 25% PDB header:oxidoreductase Chain: K: PDB Molecule:1,3-propanediol oxidoreductase; PDBTitle: crystal structure analysis of 1,3-propanediol oxidoreductase Phyre2 PDB 3f2c chain A Region: 23 - 104 Aligned: 82 Modelled: 82 Confidence: 95.9% Identity: 20% PDB header:transferase/dna Chain: A: PDB Molecule:geobacillus kaustophilus dna polc; PDBTitle: dna polymerase polc from geobacillus kaustophilus complex with dna,2 dgtp and mn Phyre2 PDB 3ox4 chain D Region: 140 - 234 Aligned: 82 Modelled: 95 Confidence: 95.9% Identity: 21% PDB header:oxidoreductase Chain: D: PDB Molecule:alcohol dehydrogenase 2; PDBTitle: structures of iron-dependent alcohol dehydrogenase 2 from zymomonas2 mobilis zm4 complexed with nad cofactor Phyre2 PDB 1oj7 chain A Region: 140 - 234 Aligned: 84 Modelled: 95 Confidence: 95.9% Identity: 18% Fold: Dehydroquinate synthase-like Superfamily: Dehydroquinate synthase-like Family: Iron-containing alcohol dehydrogenase Phyre2 PDB 1vlj chain A Region: 139 - 234 Aligned: 85 Modelled: 96 Confidence: 95.9% Identity: 19% Fold: Dehydroquinate synthase-like Superfamily: Dehydroquinate synthase-like Family: Iron-containing alcohol dehydrogenase Phyre2 PDB 1v1q chain A Region: 27 - 109 Aligned: 83 Modelled: 83 Confidence: 95.7% Identity: 17% Fold: OB-fold Superfamily: Nucleic acid-binding proteins Family: Single strand DNA-binding domain, SSB Phyre2 PDB 2ihe chain A Region: 25 - 104 Aligned: 80 Modelled: 80 Confidence: 95.4% Identity: 19% PDB header:dna binding protein Chain: A: PDB Molecule:single-stranded dna-binding protein; PDBTitle: crystal structure of wild-type single-stranded dna binding protein2 from thermus aquaticus Phyre2 PDB 3okf chain A Region: 135 - 234 Aligned: 93 Modelled: 100 Confidence: 95.4% Identity: 22% PDB header:lyase Chain: A: PDB Molecule:3-dehydroquinate synthase; PDBTitle: 2.5 angstrom resolution crystal structure of 3-dehydroquinate synthase2 (arob) from vibrio cholerae Phyre2 PDB 1rrm chain A Region: 140 - 234 Aligned: 82 Modelled: 95 Confidence: 95.4% Identity: 21% Fold: Dehydroquinate synthase-like Superfamily: Dehydroquinate synthase-like Family: Iron-containing alcohol dehydrogenase Phyre2 PDB 1o2d chain A Region: 135 - 234 Aligned: 87 Modelled: 100 Confidence: 95.3% Identity: 26% Fold: Dehydroquinate synthase-like Superfamily: Dehydroquinate synthase-like Family: Iron-containing alcohol dehydrogenase Phyre2 PDB 1bbu chain A domain 1 Region: 2 - 103 Aligned: 100 Modelled: 102 Confidence: 95.2% Identity: 15% Fold: OB-fold Superfamily: Nucleic acid-binding proteins Family: Anticodon-binding domain Phyre2 PDB 3qvj chain B Region: 141 - 234 Aligned: 83 Modelled: 94 Confidence: 95.2% Identity: 18% PDB header:isomerase Chain: B: PDB Molecule:putative hydantoin racemase; PDBTitle: allantoin racemase from klebsiella pneumoniae Phyre2 PDB 3e0e chain A Region: 29 - 101 Aligned: 66 Modelled: 73 Confidence: 95.1% Identity: 24% PDB header:replication Chain: A: PDB Molecule:replication protein a; PDBTitle: crystal structure of a domain of replication protein a from2 methanococcus maripaludis. northeast structural genomics3 targe mrr110b Phyre2 PDB 1l0w chain A domain 1 Region: 28 - 106 Aligned: 78 Modelled: 79 Confidence: 95.0% Identity: 14% Fold: OB-fold Superfamily: Nucleic acid-binding proteins Family: Anticodon-binding domain Phyre2 PDB 1gm5 chain A domain 2 Region: 28 - 105 Aligned: 78 Modelled: 78 Confidence: 95.0% Identity: 19% Fold: OB-fold Superfamily: Nucleic acid-binding proteins Family: RecG "wedge" domain Phyre2 PDB 3bju chain B Region: 2 - 103 Aligned: 101 Modelled: 102 Confidence: 95.0% Identity: 12% PDB header:ligase Chain: B: PDB Molecule:lysyl-trna synthetase; PDBTitle: crystal structure of tetrameric form of human lysyl-trna2 synthetase Phyre2 PDB 3hl0 chain B Region: 139 - 234 Aligned: 82 Modelled: 96 Confidence: 94.8% Identity: 17% PDB header:oxidoreductase Chain: B: PDB Molecule:maleylacetate reductase; PDBTitle: crystal structure of maleylacetate reductase from agrobacterium2 tumefaciens Phyre2 PDB 1e1o chain A domain 1 Region: 2 - 102 Aligned: 99 Modelled: 101 Confidence: 94.7% Identity: 17% Fold: OB-fold Superfamily: Nucleic acid-binding proteins Family: Anticodon-binding domain Phyre2 PDB 2nu7 chain B domain 1 Region: 141 - 264 Aligned: 114 Modelled: 114 Confidence: 93.4% Identity: 18% Fold: Flavodoxin-like Superfamily: Succinyl-CoA synthetase domains Family: Succinyl-CoA synthetase domains Phyre2 PDB 1smy chain F domain 2 Region: 234 - 336 Aligned: 91 Modelled: 91 Confidence: 81.5% Identity: 20% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Sigma3 and sigma4 domains of RNA polymerase sigma factors Family: Sigma4 domain Phyre2 PDB 1dm9 chain A Region: 399 - 451 Aligned: 50 Modelled: 50 Confidence: 80.2% Identity: 22% Fold: Alpha-L RNA-binding motif Superfamily: Alpha-L RNA-binding motif Family: Heat shock protein 15 kD Phyre2 PDB 1dm9 chain A Region: 399 - 451 Aligned: 50 Modelled: 50 Confidence: 80.2% Identity: 22% PDB header:structural genomics Chain: A: PDB Molecule:hypothetical 15.5 kd protein in mrca-pcka PDBTitle: heat shock protein 15 kd Phyre2 1 c3kf6A_ 2 c1z9fA_ 3 c3bfjK_ 4 c3f2cA_ 5 c3ox4D_ 6 d1oj7a_ 7 d1vlja_ 8 d1v1qa_ 9 c2iheA_ 10 c3okfA_ 11 d1rrma_ 12 d1o2da_ 13 d1bbua1 14 c3qvjB_ 15 c3e0eA_ 16 d1l0wa1 17 d1gm5a2 18 c3bjuB_ 19 c3hl0B_ 20 d1e1oa1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 d2nu7b1 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 d1smyf2 148 149 150 151 152 153 154 155 156 157 158 d1dm9a_ 159 c1dm9A_ 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499