Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP42906
DateThu Jan 5 12:02:04 GMT 2012
Unique Job ID0e412bde123da103

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1yrra2
Top template information
Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
Confidence and coverage
Confidence:100.0% Coverage: 81%
135 residues ( 81% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MHCYNGMTGLHHREPGMVGAGLTDKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDA
Secondary structure 





























SS confidence 



























































Disorder  ?????






















































Disorder confidence 



























































 
   .........70.........80.........90.........100.........110.........120
Sequence  MQAAGMPDGRYTLCGEEVQMHGGVVRTASGGLAGSTLSVDAAVRNMVELTGVTPAEAIHM
Secondary structure 






















SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........130.........140.........150.........160.......
Sequence  ASLHPARMLGVDGVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF
Secondary structure 



















SS confidence 














































Disorder 












































??
Disorder confidence 














































 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1yrr chain A domain 2

3D model

Region: 2 - 136
Aligned: 135
Modelled: 135
Confidence: 100.0%
Identity: 36%
Fold: TIM beta/alpha-barrel
Superfamily: Metallo-dependent hydrolases
Family: N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain

Phyre2

PDB 1un7 chain A domain 2

3D model

Region: 2 - 136
Aligned: 135
Modelled: 135
Confidence: 100.0%
Identity: 38%
Fold: TIM beta/alpha-barrel
Superfamily: Metallo-dependent hydrolases
Family: N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain

Phyre2

PDB 3egj chain A

3D model

Region: 1 - 166
Aligned: 166
Modelled: 166
Confidence: 100.0%
Identity: 36%
PDB header:hydrolase
Chain: A: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase;
PDBTitle: n-acetylglucosamine-6-phosphate deacetylase from vibrio cholerae.

Phyre2

PDB 2vhl chain B

3D model

Region: 1 - 166
Aligned: 166
Modelled: 166
Confidence: 100.0%
Identity: 36%
PDB header:hydrolase
Chain: B: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase;
PDBTitle: the three-dimensional structure of the n-acetylglucosamine-2 6-phosphate deacetylase from bacillus subtilis

Phyre2

PDB 1o12 chain B

3D model

Region: 1 - 166
Aligned: 165
Modelled: 166
Confidence: 100.0%
Identity: 39%
PDB header:hydrolase
Chain: B: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase;
PDBTitle: crystal structure of n-acetylglucosamine-6-phosphate2 deacetylase (tm0814) from thermotoga maritima at 2.5 a3 resolution

Phyre2

PDB 2p50 chain C

3D model

Region: 1 - 165
Aligned: 138
Modelled: 138
Confidence: 99.9%
Identity: 37%
PDB header:hydrolase
Chain: C: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase;
PDBTitle: crystal structure of n-acetyl-d-glucosamine-6-phosphate deacetylase2 liganded with zn

Phyre2

PDB 2gok chain A

3D model

Region: 2 - 166
Aligned: 162
Modelled: 165
Confidence: 99.8%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:imidazolonepropionase;
PDBTitle: crystal structure of the imidazolonepropionase from agrobacterium2 tumefaciens at 1.87 a resolution

Phyre2

PDB 2bb0 chain A

3D model

Region: 2 - 166
Aligned: 162
Modelled: 165
Confidence: 99.8%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:imidazolonepropionase;
PDBTitle: structure of imidazolonepropionase from bacillus subtilis

Phyre2

PDB 3e0l chain B

3D model

Region: 30 - 165
Aligned: 130
Modelled: 136
Confidence: 99.8%
Identity: 21%
PDB header:hydrolase
Chain: B: PDB Molecule:guanine deaminase;
PDBTitle: computationally designed ammelide deaminase

Phyre2

PDB 3hm7 chain A

3D model

Region: 87 - 166
Aligned: 80
Modelled: 80
Confidence: 99.8%
Identity: 23%
PDB header:hydrolase
Chain: A: PDB Molecule:allantoinase;
PDBTitle: crystal structure of allantoinase from bacillus halodurans c-125

Phyre2

PDB 2aqo chain B

3D model

Region: 31 - 166
Aligned: 135
Modelled: 136
Confidence: 99.7%
Identity: 13%
PDB header:hydrolase
Chain: B: PDB Molecule:isoaspartyl dipeptidase;
PDBTitle: crystal structure of e. coli isoaspartyl dipeptidase mutant e77q

Phyre2

PDB 2q09 chain A

3D model

Region: 2 - 167
Aligned: 163
Modelled: 166
Confidence: 99.7%
Identity: 17%
PDB header:hydrolase
Chain: A: PDB Molecule:imidazolonepropionase;
PDBTitle: crystal structure of imidazolonepropionase from environmental sample2 with bound inhibitor 3-(2,5-dioxo-imidazolidin-4-yl)-propionic acid

Phyre2

PDB 2vr2 chain A

3D model

Region: 89 - 166
Aligned: 78
Modelled: 78
Confidence: 99.7%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:dihydropyrimidinase;
PDBTitle: human dihydropyrimidinase

Phyre2

PDB 3lnp chain A

3D model

Region: 31 - 166
Aligned: 136
Modelled: 136
Confidence: 99.7%
Identity: 19%
PDB header:hydrolase
Chain: A: PDB Molecule:amidohydrolase family protein olei01672_1_465;
PDBTitle: crystal structure of amidohydrolase family protein2 olei01672_1_465 from oleispira antarctica

Phyre2

PDB 3ooq chain C

3D model

Region: 31 - 166
Aligned: 135
Modelled: 136
Confidence: 99.7%
Identity: 13%
PDB header:hydrolase
Chain: C: PDB Molecule:amidohydrolase;
PDBTitle: crystal structure of amidohydrolase from thermotoga maritima msb8

Phyre2

PDB 1gkr chain A

3D model

Region: 88 - 166
Aligned: 79
Modelled: 79
Confidence: 99.7%
Identity: 22%
PDB header:hydrolase
Chain: A: PDB Molecule:non-atp dependent l-selective hydantoinase;
PDBTitle: l-hydantoinase (dihydropyrimidinase) from arthrobacter2 aurescens

Phyre2

PDB 2ftw chain A

3D model

Region: 90 - 166
Aligned: 77
Modelled: 77
Confidence: 99.7%
Identity: 17%
PDB header:hydrolase
Chain: A: PDB Molecule:dihydropyrimidine amidohydrolase;
PDBTitle: crystal structure of dihydropyrimidinase from dictyostelium discoideum

Phyre2

PDB 2p9b chain A

3D model

Region: 87 - 166
Aligned: 80
Modelled: 80
Confidence: 99.7%
Identity: 34%
PDB header:hydrolase
Chain: A: PDB Molecule:possible prolidase;
PDBTitle: crystal structure of putative prolidase from2 bifidobacterium longum

Phyre2

PDB 1gkp chain D

3D model

Region: 89 - 166
Aligned: 78
Modelled: 78
Confidence: 99.7%
Identity: 18%
PDB header:hydrolase
Chain: D: PDB Molecule:hydantoinase;
PDBTitle: d-hydantoinase (dihydropyrimidinase) from thermus sp. in2 space group c2221

Phyre2

PDB 2gse chain C

3D model

Region: 89 - 166
Aligned: 78
Modelled: 78
Confidence: 99.7%
Identity: 17%
PDB header:hydrolase
Chain: C: PDB Molecule:dihydropyrimidinase-related protein 2;
PDBTitle: crystal structure of human dihydropyrimidinease-like 2

Phyre2
1

d1yrra2
2

d1un7a2
3

c3egjA_
4

c2vhlB_
5

c1o12B_
6

c2p50C_
7

c2gokA_
8

c2bb0A_
9

c3e0lB_
10

c3hm7A_
11

c2aqoB_
12

c2q09A_
13

c2vr2A_
14

c3lnpA_
15

c3ooqC_
16

c1gkrA_
17

c2ftwA_
18

c2p9bA_
19

c1gkpD_
20

c2gseC_
21



22



23



24



25



26



27



28



29



30



31



32



33



34



35



36



37



38



39



40



41



42



43



44



45



46



47



48



49



50



51



52



53



54



55



56



57



58



59



60



61



62



63



64



65



66



67



68



69



70



71



72



73



74



75



76



77



78



79



80



81



82



83



84



85



86



87



88



89



90



91



92



93



94



95



96



97



98



99



100



101



102



103



104



105



106



107



108



109



110



111



112



113



114



115



116



117



118



119



120



121



122



123



124



125



126



127



128



129



130



131



132



133



134



135



136



137



138



139






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1yrra2



100.0 36 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
2d1un7a2



100.0 38 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
3c3egjA_



100.0 36 PDB header:hydrolase
Chain: A: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase;
PDBTitle: n-acetylglucosamine-6-phosphate deacetylase from vibrio cholerae.
4c2vhlB_



100.0 36 PDB header:hydrolase
Chain: B: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase;
PDBTitle: the three-dimensional structure of the n-acetylglucosamine-2 6-phosphate deacetylase from bacillus subtilis
5c1o12B_



100.0 39 PDB header:hydrolase
Chain: B: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase;
PDBTitle: crystal structure of n-acetylglucosamine-6-phosphate2 deacetylase (tm0814) from thermotoga maritima at 2.5 a3 resolution
6c2p50C_



99.9 37 PDB header:hydrolase
Chain: C: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase;
PDBTitle: crystal structure of n-acetyl-d-glucosamine-6-phosphate deacetylase2 liganded with zn
7c2gokA_



99.8 14 PDB header:hydrolase
Chain: A: PDB Molecule:imidazolonepropionase;
PDBTitle: crystal structure of the imidazolonepropionase from agrobacterium2 tumefaciens at 1.87 a resolution
8c2bb0A_



99.8 15 PDB header:hydrolase
Chain: A: PDB Molecule:imidazolonepropionase;
PDBTitle: structure of imidazolonepropionase from bacillus subtilis
9c3e0lB_



99.8 21 PDB header:hydrolase
Chain: B: PDB Molecule:guanine deaminase;
PDBTitle: computationally designed ammelide deaminase
10c3hm7A_



99.8 23 PDB header:hydrolase
Chain: A: PDB Molecule:allantoinase;
PDBTitle: crystal structure of allantoinase from bacillus halodurans c-125
11c2aqoB_



99.7 13 PDB header:hydrolase
Chain: B: PDB Molecule:isoaspartyl dipeptidase;
PDBTitle: crystal structure of e. coli isoaspartyl dipeptidase mutant e77q
12c2q09A_



99.7 17 PDB header:hydrolase
Chain: A: PDB Molecule:imidazolonepropionase;
PDBTitle: crystal structure of imidazolonepropionase from environmental sample2 with bound inhibitor 3-(2,5-dioxo-imidazolidin-4-yl)-propionic acid
13c2vr2A_



99.7 14 PDB header:hydrolase
Chain: A: PDB Molecule:dihydropyrimidinase;
PDBTitle: human dihydropyrimidinase
14c3lnpA_



99.7 19 PDB header:hydrolase
Chain: A: PDB Molecule:amidohydrolase family protein olei01672_1_465;
PDBTitle: crystal structure of amidohydrolase family protein2 olei01672_1_465 from oleispira antarctica
15c3ooqC_



99.7 13 PDB header:hydrolase
Chain: C: PDB Molecule:amidohydrolase;
PDBTitle: crystal structure of amidohydrolase from thermotoga maritima msb8
16c1gkrA_



99.7 22 PDB header:hydrolase
Chain: A: PDB Molecule:non-atp dependent l-selective hydantoinase;
PDBTitle: l-hydantoinase (dihydropyrimidinase) from arthrobacter2 aurescens
17c2ftwA_



99.7 17 PDB header:hydrolase
Chain: A: PDB Molecule:dihydropyrimidine amidohydrolase;
PDBTitle: crystal structure of dihydropyrimidinase from dictyostelium discoideum
18c2p9bA_



99.7 34 PDB header:hydrolase
Chain: A: PDB Molecule:possible prolidase;
PDBTitle: crystal structure of putative prolidase from2 bifidobacterium longum
19c1gkpD_



99.7 18 PDB header:hydrolase
Chain: D: PDB Molecule:hydantoinase;
PDBTitle: d-hydantoinase (dihydropyrimidinase) from thermus sp. in2 space group c2221
20c2gseC_



99.7 17 PDB header:hydrolase
Chain: C: PDB Molecule:dihydropyrimidinase-related protein 2;
PDBTitle: crystal structure of human dihydropyrimidinease-like 2
21c3gnhA_



not modelled 99.7 23 PDB header:hydrolase
Chain: A: PDB Molecule:l-lysine, l-arginine carboxypeptidase cc2672;
PDBTitle: crystal structure of l-lysine, l-arginine carboxypeptidase cc2672 from2 caulobacter crescentus cb15 complexed with n-methyl phosphonate3 derivative of l-arginine.
22c3hpaB_



not modelled 99.7 18 PDB header:hydrolase
Chain: B: PDB Molecule:amidohydrolase;
PDBTitle: crystal structure of an amidohydrolase gi:44264246 from an2 evironmental sample of sargasso sea
23c2i9uA_



not modelled 99.7 19 PDB header:hydrolase
Chain: A: PDB Molecule:cytosine/guanine deaminase related protein;
PDBTitle: crystal structure of guanine deaminase from c. acetobutylicum with2 bound guanine in the active site
24c3feqB_



not modelled 99.7 23 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative amidohydrolase;
PDBTitle: crystal structure of uncharacterized protein eah89906
25c3nqbB_



not modelled 99.7 30 PDB header:hydrolase
Chain: B: PDB Molecule:adenine deaminase 2;
PDBTitle: crystal structure of adenine deaminase from agrobacterium tumefaciens2 (str. c 58)
26c1k1dF_



not modelled 99.7 17 PDB header:hydrolase
Chain: F: PDB Molecule:d-hydantoinase;
PDBTitle: crystal structure of d-hydantoinase
27c2oodA_



not modelled 99.7 32 PDB header:hydrolase
Chain: A: PDB Molecule:blr3880 protein;
PDBTitle: crystal structure of guanine deaminase from bradyrhizobium japonicum
28c3dc8B_



not modelled 99.7 18 PDB header:hydrolase
Chain: B: PDB Molecule:dihydropyrimidinase;
PDBTitle: crystal structure of dihydropyrimidinase from sinorhizobium meliloti
29c3griB_



not modelled 99.7 17 PDB header:hydrolase
Chain: B: PDB Molecule:dihydroorotase;
PDBTitle: the crystal structure of a dihydroorotase from staphylococcus aureus
30c1nfgA_



not modelled 99.7 15 PDB header:hydrolase
Chain: A: PDB Molecule:d-hydantoinase;
PDBTitle: structure of d-hydantoinase
31d1o12a2



not modelled 99.7 42 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
32c1p1mA_



not modelled 99.7 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein tm0936;
PDBTitle: structure of thermotoga maritima amidohydrolase tm09362 bound to ni and methionine
33c2z00A_



not modelled 99.7 20 PDB header:hydrolase
Chain: A: PDB Molecule:dihydroorotase;
PDBTitle: crystal structure of dihydroorotase from thermus thermophilus
34c2r8cB_



not modelled 99.7 28 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative amidohydrolase;
PDBTitle: crystal structure of uncharacterized protein eaj56179
35c3be7B_



not modelled 99.7 23 PDB header:hydrolase
Chain: B: PDB Molecule:zn-dependent arginine carboxypeptidase;
PDBTitle: crystal structure of zn-dependent arginine carboxypeptidase
36c2gwnA_



not modelled 99.6 24 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:dihydroorotase;
PDBTitle: the structure of putative dihydroorotase from porphyromonas2 gingivalis.
37c2fvmA_



not modelled 99.6 19 PDB header:hydrolase
Chain: A: PDB Molecule:dihydropyrimidinase;
PDBTitle: crystal structure of dihydropyrimidinase from saccharomyces kluyveri2 in complex with the reaction product n-carbamyl-beta-alanine
38c2qs8A_



not modelled 99.6 23 PDB header:hydrolase
Chain: A: PDB Molecule:xaa-pro dipeptidase;
PDBTitle: crystal structure of a xaa-pro dipeptidase with bound2 methionine in the active site
39c1xrfA_



not modelled 99.6 15 PDB header:hydrolase
Chain: A: PDB Molecule:dihydroorotase;
PDBTitle: the crystal structure of a novel, latent dihydroorotase from aquifex2 aeolicus at 1.7 a resolution
40c3e74D_



not modelled 99.6 22 PDB header:hydrolase
Chain: D: PDB Molecule:allantoinase;
PDBTitle: crystal structure of e. coli allantoinase with iron ions at2 the metal center
41c2ogjB_



not modelled 99.6 18 PDB header:hydrolase
Chain: B: PDB Molecule:dihydroorotase;
PDBTitle: crystal structure of a dihydroorotase
42c2pajA_



not modelled 99.6 17 PDB header:hydrolase
Chain: A: PDB Molecule:putative cytosine/guanine deaminase;
PDBTitle: crystal structure of an amidohydrolase from an environmental sample of2 sargasso sea
43c3mpgB_



not modelled 99.6 24 PDB header:hydrolase
Chain: B: PDB Molecule:dihydroorotase;
PDBTitle: dihydroorotase from bacillus anthracis
44c3gipB_



not modelled 99.6 23 PDB header:hydrolase
Chain: B: PDB Molecule:n-acyl-d-glutamate deacylase;
PDBTitle: crystal structure of n-acyl-d-glutamate deacylase from2 bordetella bronchiseptica complexed with zinc, acetate and3 formate ions.
45c1rjqA_



not modelled 99.6 18 PDB header:hydrolase
Chain: A: PDB Molecule:d-aminoacylase;
PDBTitle: the crystal structure of the d-aminoacylase mutant d366a
46c3mduA_



not modelled 99.6 23 PDB header:hydrolase
Chain: A: PDB Molecule:n-formimino-l-glutamate iminohydrolase;
PDBTitle: the structure of n-formimino-l-glutamate iminohydrolase from2 pseudomonas aeruginosa complexed with n-guanidino-l-glutamate
47c3d6nA_



not modelled 99.6 30 PDB header:hydrolase/transferase
Chain: A: PDB Molecule:dihydroorotase;
PDBTitle: crystal structure of aquifex dihydroorotase activated by aspartate2 transcarbamoylase
48c1fwcC_



not modelled 99.6 21 PDB header:hydrolase
Chain: C: PDB Molecule:urease;
PDBTitle: klebsiella aerogenes urease, c319a variant at ph 8.5
49c3lsbA_



not modelled 99.6 15 PDB header:hydrolase
Chain: A: PDB Molecule:triazine hydrolase;
PDBTitle: crystal structure of the mutant e241q of atrazine chlorohydrolase trzn2 from arthrobacter aurescens tc1 complexed with zinc and ametrin
50c2vunC_



not modelled 99.6 21 PDB header:hydrolase
Chain: C: PDB Molecule:enamidase;
PDBTitle: the crystal structure of enamidase at 1.9 a resolution - a2 new member of the amidohydrolase superfamily
51c2ubpC_



not modelled 99.6 19 PDB header:hydrolase
Chain: C: PDB Molecule:protein (urease alpha subunit);
PDBTitle: structure of native urease from bacillus pasteurii
52c1e9yB_



not modelled 99.6 21 PDB header:hydrolase
Chain: B: PDB Molecule:urease subunit beta;
PDBTitle: crystal structure of helicobacter pylori urease in complex with2 acetohydroxamic acid
53c1r9yA_



not modelled 99.5 16 PDB header:hydrolase
Chain: A: PDB Molecule:cytosine deaminase;
PDBTitle: bacterial cytosine deaminase d314a mutant.
54c2icsA_



not modelled 99.5 16 PDB header:hydrolase
Chain: A: PDB Molecule:adenine deaminase;
PDBTitle: crystal structure of an adenine deaminase
55c2qt3A_



not modelled 99.5 19 PDB header:hydrolase
Chain: A: PDB Molecule:n-isopropylammelide isopropyl amidohydrolase;
PDBTitle: crystal structure of n-isopropylammelide isopropylaminohydrolase atzc2 from pseudomonas sp. strain adp complexed with zn
56c3la4A_



not modelled 99.4 22 PDB header:hydrolase
Chain: A: PDB Molecule:urease;
PDBTitle: crystal structure of the first plant urease from jack bean (canavalia2 ensiformis)
57c3etkA_



not modelled 99.3 23 PDB header:hydrolase
Chain: A: PDB Molecule:uncharacterized metal-dependent hydrolase;
PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from pyrococcus furiosus
58c3ighX_



not modelled 99.3 22 PDB header:hydrolase
Chain: X: PDB Molecule:uncharacterized metal-dependent hydrolase;
PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from pyrococcus horikoshii ot3
59d4ubpc2



not modelled 99.2 20 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:alpha-subunit of urease, catalytic domain
60d1gkpa2



not modelled 99.2 16 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
61c2imrA_



not modelled 99.1 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein dr_0824;
PDBTitle: crystal structure of amidohydrolase dr_0824 from2 deinococcus radiodurans
62d3be7a1



not modelled 99.1 22 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Zn-dependent arginine carboxypeptidase-like
63d2bb0a1



not modelled 98.9 26 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Imidazolonepropionase-like
64d1nfga1



not modelled 98.8 13 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase)
65c3msrA_



not modelled 98.8 17 PDB header:hydrolase
Chain: A: PDB Molecule:amidohydrolases;
PDBTitle: the crystal structure of an amidohydrolase from mycoplasma synoviae
66d1ra0a2



not modelled 98.8 13 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Cytosine deaminase catalytic domain
67d2bb0a2



not modelled 98.7 11 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Imidazolonepropionase-like
68d2paja1



not modelled 98.7 19 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:SAH/MTA deaminase-like
69d2q09a2



not modelled 98.6 17 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Imidazolonepropionase-like
70d2puza2



not modelled 98.6 12 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Imidazolonepropionase-like
71d2uz9a2



not modelled 98.5 19 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:SAH/MTA deaminase-like
72d1kcxa2



not modelled 98.4 12 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
73d2ftwa2



not modelled 98.4 19 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
74d2p9ba2



not modelled 98.4 33 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Imidazolonepropionase-like
75d2paja2



not modelled 98.4 17 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:SAH/MTA deaminase-like
76d2icsa2



not modelled 98.3 12 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Adenine deaminase-like
77d2qs8a1



not modelled 98.3 27 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Zn-dependent arginine carboxypeptidase-like
78d1p1ma1



not modelled 98.3 17 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:SAH/MTA deaminase-like
79d2ooda1



not modelled 98.3 28 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:SAH/MTA deaminase-like
80d1gkra1



not modelled 98.2 13 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase)
81d1xrta1



not modelled 98.2 31 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase)
82d2ooda2



not modelled 98.1 13 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:SAH/MTA deaminase-like
83d1ynya2



not modelled 98.1 11 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
84d3be7a2



not modelled 98.0 25 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Zn-dependent arginine carboxypeptidase-like
85d2r8ca2



not modelled 98.0 26 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Zn-dependent arginine carboxypeptidase-like
86d2qs8a2



not modelled 97.9 20 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Zn-dependent arginine carboxypeptidase-like
87d2i9ua2



not modelled 97.8 22 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:SAH/MTA deaminase-like
88d1nfga2



not modelled 97.7 15 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
89d1k1da2



not modelled 97.6 15 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
90d1onwa2



not modelled 97.6 15 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Isoaspartyl dipeptidase, catalytic domain
91d1m7ja2



not modelled 97.5 21 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:D-aminoacylase
92d2imra2



not modelled 97.5 20 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:DR0824-like
93d1gkra2



not modelled 97.5 18 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
94d1p1ma2



not modelled 97.5 9 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:SAH/MTA deaminase-like
95d1kcxa1



not modelled 97.3 21 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase)
96d1o12a1



not modelled 97.3 31 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:N-acetylglucosamine-6-phosphate deacetylase, NagA
97d2fvka2



not modelled 97.3 14 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
98d1i0da_



not modelled 97.0 17 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Phosphotriesterase-like
99d1xrta2



not modelled 97.0 17 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
100c3pnuA_



not modelled 96.4 2 PDB header:hydrolase
Chain: A: PDB Molecule:dihydroorotase;
PDBTitle: 2.4 angstrom crystal structure of dihydroorotase (pyrc) from2 campylobacter jejuni.
101d2puza1



not modelled 95.9 26 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Imidazolonepropionase-like
102d1ynya1



not modelled 95.8 24 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase)
103d1e9yb2



not modelled 95.6 25 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:alpha-subunit of urease, catalytic domain
104d1k1da1



not modelled 95.5 21 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase)
105d2i9ua1



not modelled 95.5 12 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:SAH/MTA deaminase-like
106d1gkpa1



not modelled 95.4 32 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase)
107d2d2ja1



not modelled 94.6 17 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Phosphotriesterase-like
108d1m7ja3



not modelled 94.5 18 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:D-aminoacylase, catalytic domain
109c1pscA_



not modelled 94.3 21 PDB header:hydrolase
Chain: A: PDB Molecule:phosphotriesterase;
PDBTitle: phosphotriesterase from pseudomonas diminuta
110d1yixa1



not modelled 94.3 16 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:TatD Mg-dependent DNase-like
111c3ou8A_



not modelled 94.2 11 PDB header:hydrolase
Chain: A: PDB Molecule:adenosine deaminase;
PDBTitle: the crystal structure of adenosine deaminase from pseudomonas2 aeruginosa
112c3ou8B_



not modelled 94.0 11 PDB header:hydrolase
Chain: B: PDB Molecule:adenosine deaminase;
PDBTitle: the crystal structure of adenosine deaminase from pseudomonas2 aeruginosa
113d1un7a1



not modelled 93.9 31 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:N-acetylglucosamine-6-phosphate deacetylase, NagA
114d2eg6a1



not modelled 92.5 6 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Dihydroorotase
115c3jzeC_



not modelled 92.4 15 PDB header:hydrolase
Chain: C: PDB Molecule:dihydroorotase;
PDBTitle: 1.8 angstrom resolution crystal structure of dihydroorotase (pyrc)2 from salmonella enterica subsp. enterica serovar typhimurium str. lt2
116d1bf6a_



not modelled 92.3 14 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Phosphotriesterase-like
117d2uz9a1



not modelled 91.4 21 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:SAH/MTA deaminase-like
118c2zc1A_



not modelled 89.8 22 PDB header:hydrolase
Chain: A: PDB Molecule:phosphotriesterase;
PDBTitle: organophosphorus hydrolase from deinococcus radiodurans
119d1a4ma_



not modelled 89.3 11 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Adenosine/AMP deaminase
120c2vc7A_



not modelled 89.0 13 PDB header:hydrolase
Chain: A: PDB Molecule:aryldialkylphosphatase;
PDBTitle: structural basis for natural lactonase and promiscuous2 phosphotriesterase activities

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0