Phyre 2 Results for A0ZWU1

Email	l.a.kelley@imperial.ac.uk
Description	A0ZWU1
Date	Sun Jul 8 11:45:01 BST 2012
Unique Job ID	efd1bfbb2979b31f

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c3e66B_

Top template information

PDB header:splicing
Chain: B: PDB Molecule:prp8;
PDBTitle: crystal structure of the beta-finger domain of yeast prp8

Confidence and coverage

Confidence:

49.4%

Coverage:

14%

34 residues ( 14% of your sequence) have been modelled with 49.4% confidence by the single highest scoring template.

You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.

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Warning: 63% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M N S L Q K G S Y K V I P G S S F S K N S N G L L S I K Y N F I P E S V D P S R R G V L E K A Q E A Y R L R L P S T F D

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ?
? ?
? ?
?
? ? ? ?
? ?
? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence D D R P H I F E G S C Q R A R N V D C V L I F N A K T K T F T L E H I D E I A R L N A L R N P K V S K T V P S N A I T Q

Secondary structure

SS confidence

Disorder ? ? ? ?
?
?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence S D N S Q I S E S K S T S Q S A V T T N S T R R K E K E L E A S K D G K I K P S S S N T R Y P A I S S K G P I T T D T N

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence D E P D M E V M E L D D F A K E L E L G F D Q E F N S I D D P S T V S Q T A S K P I S L R G L S S Q E R D Y A S S A Q A

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ?
? ?
? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 250 .

Sequence E G I S S A S E D E D

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 3e66 chain B

Region: 65 - 98
Aligned: 34
Modelled: 34
Confidence: 49.4%
Identity: 26%
PDB header:splicing
Chain: B: PDB Molecule:prp8;
PDBTitle: crystal structure of the beta-finger domain of yeast prp8

Phyre2

PDB 3e9o chain A domain 1

Region: 65 - 98
Aligned: 34
Modelled: 34
Confidence: 47.6%
Identity: 26%
Fold: Ribonuclease H-like motif
Superfamily: Ribonuclease H-like
Family: Prp8 beta-finger domain-like

Phyre2

PDB 3e9l chain A domain 1

Region: 65 - 98
Aligned: 34
Modelled: 34
Confidence: 40.8%
Identity: 26%
Fold: Ribonuclease H-like motif
Superfamily: Ribonuclease H-like
Family: Prp8 beta-finger domain-like

Phyre2

PDB 3enb chain A domain 1

Region: 65 - 98
Aligned: 34
Modelled: 34
Confidence: 39.9%
Identity: 26%
Fold: Ribonuclease H-like motif
Superfamily: Ribonuclease H-like
Family: Prp8 beta-finger domain-like

Phyre2

PDB 3sbg chain A

Region: 65 - 98
Aligned: 34
Modelled: 34
Confidence: 33.7%
Identity: 26%
PDB header:splicing
Chain: A: PDB Molecule:pre-mrna-splicing factor 8;
PDBTitle: crystal structure of a prp8 c-terminal fragment

Phyre2

PDB 1hx0 chain A domain 1

Region: 3 - 19
Aligned: 17
Modelled: 17
Confidence: 18.9%
Identity: 35%
Fold: Glycosyl hydrolase domain
Superfamily: Glycosyl hydrolase domain
Family: alpha-Amylases, C-terminal beta-sheet domain

Phyre2

PDB 1ujx chain A

Region: 72 - 98
Aligned: 27
Modelled: 27
Confidence: 18.7%
Identity: 11%
Fold: SMAD/FHA domain
Superfamily: SMAD/FHA domain
Family: FHA domain

Phyre2

PDB 2brf chain A domain 1

Region: 72 - 116
Aligned: 44
Modelled: 45
Confidence: 17.5%
Identity: 9%
Fold: SMAD/FHA domain
Superfamily: SMAD/FHA domain
Family: FHA domain

Phyre2

PDB 3bmv chain A domain 3

Region: 3 - 21
Aligned: 19
Modelled: 19
Confidence: 13.2%
Identity: 32%
Fold: Glycosyl hydrolase domain
Superfamily: Glycosyl hydrolase domain
Family: alpha-Amylases, C-terminal beta-sheet domain

Phyre2

PDB 3nat chain B

Region: 78 - 90
Aligned: 13
Modelled: 13
Confidence: 10.8%
Identity: 23%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of conserved protein of unknown function ef_19772 from enterococcus faecalis

Phyre2

PDB 2zkr chain 3

Region: 26 - 32
Aligned: 7
Modelled: 7
Confidence: 10.8%
Identity: 43%
PDB header:ribosomal protein/rna
Chain: 3: PDB Molecule:60s ribosomal protein l39e;
PDBTitle: structure of a mammalian ribosomal 60s subunit within an 80s complex2 obtained by docking homology models of the rna and proteins into an3 8.7 a cryo-em map

Phyre2

PDB 4a1b chain B

Region: 26 - 32
Aligned: 7
Modelled: 7
Confidence: 10.6%
Identity: 43%
PDB header:ribosome
Chain: B: PDB Molecule:rpl39;
PDBTitle: t.thermophila 60s ribosomal subunit in complex with2 initiation factor 6. this file contains 26s rrna and3 proteins of molecule 3.

Phyre2

PDB 1o12 chain A domain 1

Region: 78 - 91
Aligned: 14
Modelled: 14
Confidence: 10.4%
Identity: 36%
Fold: Composite domain of metallo-dependent hydrolases
Superfamily: Composite domain of metallo-dependent hydrolases
Family: N-acetylglucosamine-6-phosphate deacetylase, NagA

Phyre2

PDB 3btp chain B

Region: 184 - 193
Aligned: 10
Modelled: 10
Confidence: 10.2%
Identity: 50%
PDB header:dna binding protein, chaperone
Chain: B: PDB Molecule:protein vire1;
PDBTitle: crystal structure of agrobacterium tumefaciens vire2 in complex with2 its chaperone vire1: a novel fold and implications for dna binding

Phyre2

PDB 3q91 chain D

Region: 79 - 94
Aligned: 16
Modelled: 16
Confidence: 9.3%
Identity: 31%
PDB header:hydrolase
Chain: D: PDB Molecule:uridine diphosphate glucose pyrophosphatase;
PDBTitle: crystal structure of human uridine diphosphate glucose pyrophosphatase2 (nudt14)

Phyre2

PDB 1cxl chain A domain 3

Region: 3 - 21
Aligned: 19
Modelled: 19
Confidence: 9.0%
Identity: 37%
Fold: Glycosyl hydrolase domain
Superfamily: Glycosyl hydrolase domain
Family: alpha-Amylases, C-terminal beta-sheet domain

Phyre2

PDB 1bwv chain S

Region: 80 - 114
Aligned: 35
Modelled: 35
Confidence: 8.6%
Identity: 17%
Fold: RuBisCO, small subunit
Superfamily: RuBisCO, small subunit
Family: RuBisCO, small subunit

Phyre2

PDB 3nfg chain G

Region: 79 - 94
Aligned: 16
Modelled: 15
Confidence: 8.1%
Identity: 13%
PDB header:transcription
Chain: G: PDB Molecule:dna-directed rna polymerase i subunit rpa49;
PDBTitle: crystal structure of dimerization module of rna polymerase i2 subcomplex a49/a34.5

Phyre2

PDB 1pam chain A domain 3

Region: 3 - 21
Aligned: 19
Modelled: 19
Confidence: 7.3%
Identity: 37%
Fold: Glycosyl hydrolase domain
Superfamily: Glycosyl hydrolase domain
Family: alpha-Amylases, C-terminal beta-sheet domain

Phyre2

PDB 1px5 chain A domain 2

Region: 65 - 84
Aligned: 19
Modelled: 20
Confidence: 6.9%
Identity: 21%
Fold: Nucleotidyltransferase
Superfamily: Nucleotidyltransferase
Family: 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain

Phyre2