Secondary structure and disorder prediction

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Sequence		M	K	T	I	N	T	V	V	A	A	M	A	L	S	T	L	S	F	G	V	F	A	A	E	P	V	T	A	S	Q	A	Q	N	M	N	K	I	G	V	V	S	A	D	G	A	S	T	L	D	A	L	E	A	K	L	A	E	K	A	A
Secondary structure
SS confidence
Disorder		?	?	?	?													?	?				?	?	?		?	?				?	?	?	?	?									?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.
Sequence		A	A	G	A	S	G	Y	S	I	T	S	A	T	N	N	N	K	L	S	G	T	A	V	I	Y	K
Secondary structure
SS confidence
Disorder			?	?	?											?	?	?									?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2jna chain A domain 1 Region: 1 - 86 Aligned: 85 Modelled: 86 Confidence: 100.0% Identity: 29% Fold: Dodecin subunit-like Superfamily: YdgH-like Family: YdgH-like Phyre2 PDB 2noc chain A domain 1 Region: 1 - 86 Aligned: 85 Modelled: 86 Confidence: 100.0% Identity: 36% Fold: Dodecin subunit-like Superfamily: YdgH-like Family: YdgH-like Phyre2 PDB 2k4q chain A Region: 28 - 84 Aligned: 57 Modelled: 57 Confidence: 62.4% Identity: 11% PDB header:viral protein Chain: A: PDB Molecule:major tail protein v; PDBTitle: the solution structure of gpv, the major tail protein from2 bacteriophage lambda Phyre2 PDB 3dfe chain A Region: 51 - 76 Aligned: 26 Modelled: 26 Confidence: 35.9% Identity: 35% PDB header:signaling protein Chain: A: PDB Molecule:putative pii-like signaling protein; PDBTitle: crystal structure of a putative pii-like signaling protein2 (yp_323533.1) from anabaena variabilis atcc 29413 at 2.35 a3 resolution Phyre2 PDB 1hl8 chain B Region: 53 - 76 Aligned: 24 Modelled: 24 Confidence: 20.8% Identity: 21% PDB header:hydrolase Chain: B: PDB Molecule:putative alpha-l-fucosidase; PDBTitle: crystal structure of thermotoga maritima alpha-fucosidase Phyre2 PDB 3lub chain E Region: 38 - 76 Aligned: 38 Modelled: 39 Confidence: 16.4% Identity: 16% PDB header:hydrolase Chain: E: PDB Molecule:putative creatinine amidohydrolase; PDBTitle: crystal structure of putative creatinine amidohydrolase2 (yp_211512.1) from bacteroides fragilis nctc 9343 at 2.11 a3 resolution Phyre2 PDB 2jz7 chain A Region: 33 - 64 Aligned: 31 Modelled: 32 Confidence: 16.2% Identity: 19% PDB header:selenium-binding protein Chain: A: PDB Molecule:selenium binding protein; PDBTitle: solution nmr structure of selenium-binding protein from2 methanococcus vannielii Phyre2 PDB 3eyp chain B Region: 53 - 76 Aligned: 24 Modelled: 24 Confidence: 15.7% Identity: 17% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative alpha-l-fucosidase; PDBTitle: crystal structure of putative alpha-l-fucosidase from bacteroides2 thetaiotaomicron Phyre2 PDB 3no4 chain A Region: 38 - 76 Aligned: 38 Modelled: 39 Confidence: 15.1% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:creatinine amidohydrolase; PDBTitle: crystal structure of a creatinine amidohydrolase (npun_f1913) from2 nostoc punctiforme pcc 73102 at 2.00 a resolution Phyre2 PDB 3ke8 chain A Region: 23 - 64 Aligned: 40 Modelled: 42 Confidence: 15.1% Identity: 25% PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate PDBTitle: crystal structure of isph:hmbpp-complex Phyre2 PDB 3mo4 chain B Region: 53 - 76 Aligned: 24 Modelled: 24 Confidence: 14.4% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:alpha-1,3/4-fucosidase; PDBTitle: the crystal structure of an alpha-(1-3,4)-fucosidase from2 bifidobacterium longum subsp. infantis atcc 15697 Phyre2 PDB 2v82 chain A Region: 34 - 70 Aligned: 36 Modelled: 37 Confidence: 13.9% Identity: 19% PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase; PDBTitle: kdpgal complexed to kdpgal Phyre2 PDB 3dnf chain B Region: 3 - 61 Aligned: 57 Modelled: 59 Confidence: 13.6% Identity: 19% PDB header:oxidoreductase Chain: B: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate reductase; PDBTitle: structure of (e)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase,2 the terminal enzyme of the non-mevalonate pathway Phyre2 PDB 1hl9 chain A domain 2 Region: 53 - 76 Aligned: 24 Modelled: 24 Confidence: 11.3% Identity: 21% Fold: TIM beta/alpha-barrel Superfamily: (Trans)glycosidases Family: Putative alpha-L-fucosidase, catalytic domain Phyre2 PDB 2w1s chain B Region: 64 - 84 Aligned: 21 Modelled: 21 Confidence: 11.2% Identity: 24% PDB header:hydrolase Chain: B: PDB Molecule:hyaluronoglucosaminidase; PDBTitle: unique ligand binding specificity of a family 322 carbohydrate-binding module from the mu toxin produced by3 clostridium perfringens Phyre2 PDB 1v7z chain A Region: 38 - 76 Aligned: 38 Modelled: 39 Confidence: 10.8% Identity: 24% Fold: Creatininase Superfamily: Creatininase Family: Creatininase Phyre2 PDB 1kjq chain A domain 1 Region: 28 - 61 Aligned: 33 Modelled: 34 Confidence: 10.7% Identity: 15% Fold: Barrel-sandwich hybrid Superfamily: Rudiment single hybrid motif Family: BC C-terminal domain-like Phyre2 PDB 2wvs chain D Region: 53 - 76 Aligned: 24 Modelled: 24 Confidence: 10.6% Identity: 25% PDB header:hydrolase Chain: D: PDB Molecule:alpha-l-fucosidase; PDBTitle: crystal structure of an alpha-l-fucosidase gh29 trapped2 covalent intermediate from bacteroides thetaiotaomicron in3 complex with 2-fluoro-fucosyl fluoride using an e288q4 mutant Phyre2 PDB 3qkb chain B Region: 49 - 65 Aligned: 17 Modelled: 17 Confidence: 10.4% Identity: 29% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a protein with unknown function which belongs to2 pfam duf74 family (pepe_0654) from pediococcus pentosaceus atcc 257453 at 2.73 a resolution Phyre2 PDB 1txk chain A domain 2 Region: 62 - 75 Aligned: 14 Modelled: 14 Confidence: 9.4% Identity: 29% Fold: Supersandwich Superfamily: Galactose mutarotase-like Family: MdoG-like Phyre2 1 d2jnaa1 2 d2noca1 3 c2k4qA_ 4 c3dfeA_ 5 c1hl8B_ 6 c3lubE_ 7 c2jz7A_ 8 c3eypB_ 9 c3no4A_ 10 c3ke8A_ 11 c3mo4B_ 12 c2v82A_ 13 c3dnfB_ 14 d1hl9a2 15 c2w1sB_ 16 d1v7za_ 17 d1kjqa1 18 c2wvsD_ 19 c3qkbB_ 20 d1txka2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2jnaa1 100.0 29 Fold:Dodecin subunit-like Superfamily:YdgH-like Family:YdgH-like 2 d2noca1 100.0 36 Fold:Dodecin subunit-like Superfamily:YdgH-like Family:YdgH-like 3 c2k4qA_ 62.4 11 PDB header:viral protein Chain: A: PDB Molecule:major tail protein v; PDBTitle: the solution structure of gpv, the major tail protein from2 bacteriophage lambda 4 c3dfeA_ 35.9 35 PDB header:signaling protein Chain: A: PDB Molecule:putative pii-like signaling protein; PDBTitle: crystal structure of a putative pii-like signaling protein2 (yp_323533.1) from anabaena variabilis atcc 29413 at 2.35 a3 resolution 5 c1hl8B_ 20.8 21 PDB header:hydrolase Chain: B: PDB Molecule:putative alpha-l-fucosidase; PDBTitle: crystal structure of thermotoga maritima alpha-fucosidase 6 c3lubE_ 16.4 16 PDB header:hydrolase Chain: E: PDB Molecule:putative creatinine amidohydrolase; PDBTitle: crystal structure of putative creatinine amidohydrolase2 (yp_211512.1) from bacteroides fragilis nctc 9343 at 2.11 a3 resolution 7 c2jz7A_ 16.2 19 PDB header:selenium-binding protein Chain: A: PDB Molecule:selenium binding protein; PDBTitle: solution nmr structure of selenium-binding protein from2 methanococcus vannielii 8 c3eypB_ 15.7 17 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative alpha-l-fucosidase; PDBTitle: crystal structure of putative alpha-l-fucosidase from bacteroides2 thetaiotaomicron 9 c3no4A_ 15.1 26 PDB header:hydrolase Chain: A: PDB Molecule:creatinine amidohydrolase; PDBTitle: crystal structure of a creatinine amidohydrolase (npun_f1913) from2 nostoc punctiforme pcc 73102 at 2.00 a resolution 10 c3ke8A_ 15.1 25 PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate PDBTitle: crystal structure of isph:hmbpp-complex 11 c3mo4B_ 14.4 17 PDB header:hydrolase Chain: B: PDB Molecule:alpha-1,3/4-fucosidase; PDBTitle: the crystal structure of an alpha-(1-3,4)-fucosidase from2 bifidobacterium longum subsp. infantis atcc 15697 12 c2v82A_ 13.9 19 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase; PDBTitle: kdpgal complexed to kdpgal 13 c3dnfB_ 13.6 19 PDB header:oxidoreductase Chain: B: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate reductase; PDBTitle: structure of (e)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase,2 the terminal enzyme of the non-mevalonate pathway 14 d1hl9a2 11.3 21 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Putative alpha-L-fucosidase, catalytic domain 15 c2w1sB_ 11.2 24 PDB header:hydrolase Chain: B: PDB Molecule:hyaluronoglucosaminidase; PDBTitle: unique ligand binding specificity of a family 322 carbohydrate-binding module from the mu toxin produced by3 clostridium perfringens 16 d1v7za_ 10.8 24 Fold:Creatininase Superfamily:Creatininase Family:Creatininase 17 d1kjqa1 10.7 15 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:BC C-terminal domain-like 18 c2wvsD_ 10.6 25 PDB header:hydrolase Chain: D: PDB Molecule:alpha-l-fucosidase; PDBTitle: crystal structure of an alpha-l-fucosidase gh29 trapped2 covalent intermediate from bacteroides thetaiotaomicron in3 complex with 2-fluoro-fucosyl fluoride using an e288q4 mutant 19 c3qkbB_ 10.4 29 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a protein with unknown function which belongs to2 pfam duf74 family (pepe_0654) from pediococcus pentosaceus atcc 257453 at 2.73 a resolution 20 d1txka2 9.4 29 Fold:Supersandwich Superfamily:Galactose mutarotase-like Family:MdoG-like 21 c3b9nB_ not modelled 9.4 16 PDB header:oxidoreductase Chain: B: PDB Molecule:alkane monoxygenase; PDBTitle: crystal structure of long-chain alkane monooxygenase (lada) 22 c1txkA_ not modelled 9.0 29 PDB header:biosynthetic protein Chain: A: PDB Molecule:glucans biosynthesis protein g; PDBTitle: crystal structure of escherichia coli opgg 23 d3etja1 not modelled 8.3 19 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:BC C-terminal domain-like 24 d1nh2a2 not modelled 8.2 13 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 25 d1mp9a1 not modelled 7.9 25 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 26 c1oy8A_ not modelled 7.8 10 PDB header:membrane protein Chain: A: PDB Molecule:acriflavine resistance protein b; PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump 27 d1qnaa2 not modelled 7.8 17 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 28 c3eikB_ not modelled 7.6 20 PDB header:transcription Chain: B: PDB Molecule:tata-box-binding protein; PDBTitle: double stranded dna binding protein 29 c1f02T_ not modelled 7.6 33 PDB header:cell adhesion Chain: T: PDB Molecule:translocated intimin receptor; PDBTitle: crystal structure of c-terminal 282-residue fragment of2 intimin in complex with translocated intimin receptor3 (tir) intimin-binding domain 30 d1cdwa2 not modelled 7.1 17 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 31 c1mp9B_ not modelled 6.7 20 PDB header:dna binding protein Chain: B: PDB Molecule:tata-binding protein; PDBTitle: tbp from a mesothermophilic archaeon, sulfolobus2 acidocaldarius 32 d1ycga1 not modelled 6.6 11 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 33 d1aisa2 not modelled 6.6 13 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 34 c2k38A_ not modelled 6.5 31 PDB header:antimicrobial protein Chain: A: PDB Molecule:cupiennin-1a; PDBTitle: cupiennin 1a, nmr, minimized average structure 35 c2z8uQ_ not modelled 6.5 20 PDB header:transcription Chain: Q: PDB Molecule:tata-box-binding protein; PDBTitle: methanococcus jannaschii tbp 36 d1uqra_ not modelled 6.4 40 Fold:Flavodoxin-like Superfamily:Type II 3-dehydroquinate dehydratase Family:Type II 3-dehydroquinate dehydratase 37 c1d3uA_ not modelled 6.4 15 PDB header:gene regulation/dna Chain: A: PDB Molecule:tata-binding protein; PDBTitle: tata-binding protein/transcription factor (ii)b/bre+tata-2 box complex from pyrococcus woesei 38 c3gzaB_ not modelled 6.3 21 PDB header:hydrolase Chain: B: PDB Molecule:putative alpha-l-fucosidase; PDBTitle: crystal structure of putative alpha-l-fucosidase (np_812709.1) from2 bacteroides thetaiotaomicron vpi-5482 at 1.60 a resolution 39 d1gqoa_ not modelled 6.2 35 Fold:Flavodoxin-like Superfamily:Type II 3-dehydroquinate dehydratase Family:Type II 3-dehydroquinate dehydratase 40 d1nh2a1 not modelled 6.2 22 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 41 c1rm1A_ not modelled 5.9 15 PDB header:transcription/dna Chain: A: PDB Molecule:tata-box binding protein; PDBTitle: structure of a yeast tfiia/tbp/tata-box dna complex 42 c1ngmM_ not modelled 5.9 15 PDB header:transcription/dna Chain: M: PDB Molecule:transcription initiation factor tfiid; PDBTitle: crystal structure of a yeast brf1-tbp-dna ternary complex 43 d1aisa1 not modelled 5.9 26 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 44 d2g39a1 not modelled 5.9 24 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:CoA transferase alpha subunit-like 45 c2uygF_ not modelled 5.9 36 PDB header:lyase Chain: F: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystallogaphic structure of the typeii 3-dehydroquinase2 from thermus thermophilus 46 d2g1da1 not modelled 5.6 17 Fold:Ribosomal proteins S24e, L23 and L15e Superfamily:Ribosomal proteins S24e, L23 and L15e Family:Ribosomal protein S24e 47 d1mp9a2 not modelled 5.6 17 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 48 c3ir9A_ not modelled 5.4 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:peptide chain release factor subunit 1; PDBTitle: c-terminal domain of peptide chain release factor from2 methanosarcina mazei. 49 c3n8kG_ not modelled 5.4 40 PDB header:lyase Chain: G: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: type ii dehydroquinase from mycobacterium tuberculosis complexed with2 citrazinic acid 50 c3lwzC_ not modelled 5.2 25 PDB header:lyase Chain: C: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: 1.65 angstrom resolution crystal structure of type ii 3-2 dehydroquinate dehydratase (aroq) from yersinia pestis 51 c2cokA_ not modelled 5.2 8 PDB header:transferase Chain: A: PDB Molecule:poly [adp-ribose] polymerase-1; PDBTitle: solution structure of brct domain of poly(adp-ribose)2 polymerase-1

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0