Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	F	K	N	A	F	A	N	L	Q	K	V	G	K	S	L	M	L	P	V	S	V	L	P	I	A	G	I	L	L	G	V	G	S	A	N	F	S	W	L	P	A	V	V	S	H	V	M	A	E	A	G	G	S	V	F	A	N	M	P
Secondary structure
SS confidence
Disorder		?	?	?																																?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	I	F	A	I	G	V	A	L	G	F	T	N	N	D	G	V	S	A	L	A	A	V	V	A	Y	G	I	M	V	K	T	M	A	V	V	A	P	L	V	L	H	L	P	A	E	E	I	A	S	K	H	L	A	D	T	G	V	L	G
Secondary structure
SS confidence
Disorder															?	?																					?	?	?	?	?	?	?	?		?	?	?		?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	I	I	S	G	A	I	A	A	Y	M	F	N	R	F	Y	R	I	K	L	P	E	Y	L	G	F	F	A	G	K	R	F	V	P	I	I	S	G	L	A	A	I	F	T	G	V	V	L	S	F	I	W	P	P	I	G	S	A	I	Q
Secondary structure
SS confidence
Disorder																																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	F	S	Q	W	A	A	Y	Q	N	P	V	V	A	F	G	I	Y	G	F	I	E	R	C	L	V	P	F	G	L	H	H	I	W	N	V	P	F	Q	M	Q	I	G	E	Y	T	N	A	A	G	Q	V	F	H	G	D	I	P	R	Y
Secondary structure
SS confidence
Disorder																																																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		M	A	G	D	P	T	A	G	K	L	S	G	G	F	L	F	K	M	Y	G	L	P	A	A	A	I	A	I	W	H	S	A	K	P	E	N	R	A	K	V	G	G	I	M	I	S	A	A	L	T	S	F	L	T	G	I	T	E	P	I
Secondary structure
SS confidence
Disorder						?	?		?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		E	F	S	F	M	F	V	A	P	I	L	Y	I	I	H	A	I	L	A	G	L	A	F	P	I	C	I	L	L	G	M	R	D	G	T	S	F	S	H	G	L	I	D	F	I	V	L	S	G	N	S	S	K	L	W	L	F	P	I	V
Secondary structure
SS confidence
Disorder																																																?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		G	I	G	Y	A	I	V	Y	Y	T	I	F	R	V	L	I	K	A	L	D	L	K	T	P	G	R	E	D	A	T	E	D	A	K	A	T	G	T	S	E	M	A	P	A	L	V	A	A	F	G	G	K	E	N	I	T	N	L	D	A
Secondary structure
SS confidence
Disorder																		?	?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.
Sequence		C	I	T	R	L	R	V	S	V	A	D	V	S	K	V	D	Q	A	G	L	K	K	L	G	A	A	G	V	V	V	A	G	S	G	V	Q	A	I	F	G	T	K	S	D	N	L	K	T	E	M	D	E	Y	I	R	N	H
Secondary structure
SS confidence
Disorder																?																																								?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3qnq chain D Region: 1 - 395 Aligned: 392 Modelled: 395 Confidence: 100.0% Identity: 16% PDB header:membrane protein, transport protein Chain: D: PDB Molecule:pts system, cellobiose-specific iic component; PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system Phyre2 PDB 3bp8 chain C domain 1 Region: 401 - 475 Aligned: 75 Modelled: 75 Confidence: 99.6% Identity: 100% Fold: Homing endonuclease-like Superfamily: Glucose permease domain IIB Family: Glucose permease domain IIB Phyre2 PDB 1iba chain A Region: 401 - 477 Aligned: 77 Modelled: 77 Confidence: 99.5% Identity: 99% PDB header:phoshphotransferase Chain: A: PDB Molecule:glucose permease; PDBTitle: glucose permease (domain iib), nmr, 11 structures Phyre2 PDB 3ipj chain B Region: 394 - 477 Aligned: 83 Modelled: 84 Confidence: 99.4% Identity: 27% PDB header:transferase Chain: B: PDB Molecule:pts system, iiabc component; PDBTitle: the crystal structure of one domain of the pts system, iiabc component2 from clostridium difficile Phyre2 PDB 3qm3 chain C Region: 382 - 477 Aligned: 88 Modelled: 95 Confidence: 59.0% Identity: 19% PDB header:lyase Chain: C: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: 1.85 angstrom resolution crystal structure of fructose-bisphosphate2 aldolase (fba) from campylobacter jejuni Phyre2 PDB 2dla chain B Region: 399 - 439 Aligned: 40 Modelled: 41 Confidence: 48.3% Identity: 35% PDB header:replication Chain: B: PDB Molecule:397aa long hypothetical protein; PDBTitle: primase large subunit amino terminal domain from pyrococcus horikoshii Phyre2 PDB 2ifq chain A domain 1 Region: 425 - 474 Aligned: 50 Modelled: 50 Confidence: 40.3% Identity: 22% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Thioltransferase Phyre2 PDB 2diy chain A Region: 422 - 476 Aligned: 55 Modelled: 55 Confidence: 38.6% Identity: 7% PDB header:protein binding Chain: A: PDB Molecule:thioredoxin-like protein 2; PDBTitle: the solution structure of the thioredoxin domain of human2 thioredoxin-like protein 2 Phyre2 PDB 1gh2 chain A Region: 430 - 475 Aligned: 46 Modelled: 46 Confidence: 38.5% Identity: 4% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Thioltransferase Phyre2 PDB 1r26 chain A Region: 430 - 476 Aligned: 47 Modelled: 47 Confidence: 37.4% Identity: 13% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Thioltransferase Phyre2 PDB 2xbq chain B Region: 423 - 474 Aligned: 52 Modelled: 52 Confidence: 34.2% Identity: 12% PDB header:oxidoreductase Chain: B: PDB Molecule:thioredoxin; PDBTitle: crystal structure of reduced schistosoma mansoni2 thioredoxin pre-protein at 1.7 angstrom Phyre2 PDB 2rdd chain B Region: 361 - 378 Aligned: 18 Modelled: 18 Confidence: 33.0% Identity: 28% PDB header:membrane protein/transport protein Chain: B: PDB Molecule:upf0092 membrane protein yajc; PDBTitle: x-ray crystal structure of acrb in complex with a novel2 transmembrane helix. Phyre2 PDB 1fzd chain A Region: 411 - 433 Aligned: 23 Modelled: 23 Confidence: 32.9% Identity: 26% Fold: Fibrinogen C-terminal domain-like Superfamily: Fibrinogen C-terminal domain-like Family: Fibrinogen C-terminal domain-like Phyre2 PDB 3b9y chain A Region: 238 - 420 Aligned: 183 Modelled: 183 Confidence: 32.8% Identity: 14% PDB header:transport protein Chain: A: PDB Molecule:ammonium transporter family rh-like protein; PDBTitle: crystal structure of the nitrosomonas europaea rh protein Phyre2 PDB 1cpz chain A Region: 402 - 443 Aligned: 42 Modelled: 42 Confidence: 32.0% Identity: 12% Fold: Ferredoxin-like Superfamily: HMA, heavy metal-associated domain Family: HMA, heavy metal-associated domain Phyre2 PDB 3gnj chain D Region: 412 - 476 Aligned: 65 Modelled: 65 Confidence: 32.0% Identity: 14% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:thioredoxin domain protein; PDBTitle: the crystal structure of a thioredoxin-related protein from2 desulfitobacterium hafniense dcb Phyre2 PDB 3zqs chain B Region: 411 - 433 Aligned: 23 Modelled: 23 Confidence: 31.9% Identity: 22% PDB header:ligase Chain: B: PDB Molecule:e3 ubiquitin-protein ligase fancl; PDBTitle: human fancl central domain Phyre2 PDB 1osd chain A Region: 402 - 443 Aligned: 42 Modelled: 42 Confidence: 30.5% Identity: 19% Fold: Ferredoxin-like Superfamily: HMA, heavy metal-associated domain Family: HMA, heavy metal-associated domain Phyre2 PDB 1nh8 chain A domain 2 Region: 428 - 452 Aligned: 25 Modelled: 25 Confidence: 30.5% Identity: 16% Fold: Ferredoxin-like Superfamily: GlnB-like Family: ATP phosphoribosyltransferase (ATP-PRTase, HisG), regulatory C-terminal domain Phyre2 PDB 1l0w chain A domain 3 Region: 403 - 446 Aligned: 44 Modelled: 44 Confidence: 29.2% Identity: 23% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 1 c3qnqD_ 2 d3bp8c1 3 c1ibaA_ 4 c3ipjB_ 5 c3qm3C_ 6 c2dlaB_ 7 d2ifqa1 8 c2diyA_ 9 d1gh2a_ 10 d1r26a_ 11 c2xbqB_ 12 c2rddB_ 13 d1fzda_ 14 c3b9yA_ 15 d1cpza_ 16 c3gnjD_ 17 c3zqsB_ 18 d1osda_ 19 d1nh8a2 20 d1l0wa3 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3qnqD_ 100.0 16 PDB header:membrane protein, transport protein Chain: D: PDB Molecule:pts system, cellobiose-specific iic component; PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system 2 d3bp8c1 99.6 100 Fold:Homing endonuclease-like Superfamily:Glucose permease domain IIB Family:Glucose permease domain IIB 3 c1ibaA_ 99.5 99 PDB header:phoshphotransferase Chain: A: PDB Molecule:glucose permease; PDBTitle: glucose permease (domain iib), nmr, 11 structures 4 c3ipjB_ 99.4 27 PDB header:transferase Chain: B: PDB Molecule:pts system, iiabc component; PDBTitle: the crystal structure of one domain of the pts system, iiabc component2 from clostridium difficile 5 c3qm3C_ 59.0 19 PDB header:lyase Chain: C: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: 1.85 angstrom resolution crystal structure of fructose-bisphosphate2 aldolase (fba) from campylobacter jejuni 6 c2dlaB_ 48.3 35 PDB header:replication Chain: B: PDB Molecule:397aa long hypothetical protein; PDBTitle: primase large subunit amino terminal domain from pyrococcus horikoshii 7 d2ifqa1 40.3 22 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 8 c2diyA_ 38.6 7 PDB header:protein binding Chain: A: PDB Molecule:thioredoxin-like protein 2; PDBTitle: the solution structure of the thioredoxin domain of human2 thioredoxin-like protein 2 9 d1gh2a_ 38.5 4 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 10 d1r26a_ 37.4 13 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 11 c2xbqB_ 34.2 12 PDB header:oxidoreductase Chain: B: PDB Molecule:thioredoxin; PDBTitle: crystal structure of reduced schistosoma mansoni2 thioredoxin pre-protein at 1.7 angstrom 12 c2rddB_ 33.0 28 PDB header:membrane protein/transport protein Chain: B: PDB Molecule:upf0092 membrane protein yajc; PDBTitle: x-ray crystal structure of acrb in complex with a novel2 transmembrane helix. 13 d1fzda_ 32.9 26 Fold:Fibrinogen C-terminal domain-like Superfamily:Fibrinogen C-terminal domain-like Family:Fibrinogen C-terminal domain-like 14 c3b9yA_ 32.8 14 PDB header:transport protein Chain: A: PDB Molecule:ammonium transporter family rh-like protein; PDBTitle: crystal structure of the nitrosomonas europaea rh protein 15 d1cpza_ 32.0 12 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 16 c3gnjD_ 32.0 14 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:thioredoxin domain protein; PDBTitle: the crystal structure of a thioredoxin-related protein from2 desulfitobacterium hafniense dcb 17 c3zqsB_ 31.9 22 PDB header:ligase Chain: B: PDB Molecule:e3 ubiquitin-protein ligase fancl; PDBTitle: human fancl central domain 18 d1osda_ 30.5 19 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 19 d1nh8a2 30.5 16 Fold:Ferredoxin-like Superfamily:GlnB-like Family:ATP phosphoribosyltransferase (ATP-PRTase, HisG), regulatory C-terminal domain 20 d1l0wa3 29.2 23 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 21 c1yjrA_ not modelled 29.1 5 PDB header:hydrolase Chain: A: PDB Molecule:copper-transporting atpase 1; PDBTitle: solution structure of the apo form of the sixth soluble2 domain a69p mutant of menkes protein 22 c2k5jB_ not modelled 28.8 29 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein yiif; PDBTitle: solution structure of protein yiif from shigella flexneri2 serotype 5b (strain 8401) . northeast structural genomics3 consortium target sft1 23 d2axtk1 not modelled 28.6 37 Fold:Single transmembrane helix Superfamily:Photosystem II reaction center protein K, PsbK Family:PsbK-like 24 c3d22A_ not modelled 28.0 11 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin h-type; PDBTitle: crystal structure of a poplar thioredoxin h mutant,2 pttrxh4c61s 25 d1fida_ not modelled 27.8 35 Fold:Fibrinogen C-terminal domain-like Superfamily:Fibrinogen C-terminal domain-like Family:Fibrinogen C-terminal domain-like 26 d1p6ta1 not modelled 27.7 14 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 27 d1q8la_ not modelled 27.4 7 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 28 c3mgjA_ not modelled 27.1 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein mj1480; PDBTitle: crystal structure of the saccharop_dh_n domain of mj14802 protein from methanococcus jannaschii. northeast structural3 genomics consortium target mjr83a. 29 c2wz9A_ not modelled 27.0 5 PDB header:protein binding Chain: A: PDB Molecule:glutaredoxin-3; PDBTitle: crystal structure of the thioredoxin domain of human txnl2 30 c2oarA_ not modelled 26.9 4 PDB header:membrane protein Chain: A: PDB Molecule:large-conductance mechanosensitive channel; PDBTitle: mechanosensitive channel of large conductance (mscl) 31 d2v0fa1 not modelled 26.8 17 Fold:GYF/BRK domain-like Superfamily:BRK domain-like Family:BRK domain-like 32 d2cfua2 not modelled 26.8 16 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Alkylsulfatase-like 33 d1kvja_ not modelled 26.7 7 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 34 c1jdpA_ not modelled 26.5 21 PDB header:signaling protein Chain: A: PDB Molecule:atrial natriuretic peptide clearance receptor; PDBTitle: crystal structure of hormone/receptor complex 35 d1jdpa_ not modelled 26.5 21 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 36 c3a0bK_ not modelled 26.1 33 PDB header:electron transport Chain: K: PDB Molecule:photosystem ii reaction center protein k; PDBTitle: crystal structure of br-substituted photosystem ii complex 37 c2ga7A_ not modelled 26.0 12 PDB header:hydrolase Chain: A: PDB Molecule:copper-transporting atpase 1; PDBTitle: solution structure of the copper(i) form of the third metal-2 binding domain of atp7a protein (menkes disease protein) 38 c2l3mA_ not modelled 25.4 14 PDB header:metal binding protein Chain: A: PDB Molecule:copper-ion-binding protein; PDBTitle: solution structure of the putative copper-ion-binding protein from2 bacillus anthracis str. ames 39 c2oi2A_ not modelled 25.2 14 PDB header:transferase Chain: A: PDB Molecule:mevalonate kinase; PDBTitle: streptococcus pneumoniae mevalonate kinase in complex with2 diphosphomevalonate 40 d1neea1 not modelled 25.1 17 Fold:Ribosome binding domain-like Superfamily:Translation initiation factor 2 beta, aIF2beta, N-terminal domain Family:Translation initiation factor 2 beta, aIF2beta, N-terminal domain 41 c3a0hk_ not modelled 25.0 33 PDB header:electron transport Chain: K: PDB Molecule:photosystem ii reaction center protein k; PDBTitle: crystal structure of i-substituted photosystem ii complex 42 c2ldiA_ not modelled 24.9 14 PDB header:hydrolase Chain: A: PDB Molecule:zinc-transporting atpase; PDBTitle: nmr solution structure of ziaan sub mutant 43 c1p68A_ not modelled 24.9 45 PDB header:de novo protein Chain: A: PDB Molecule:de novo designed protein s-824; PDBTitle: solution structure of s-824, a de novo designed four helix2 bundle 44 d1a8ra_ not modelled 24.3 27 Fold:T-fold Superfamily:Tetrahydrobiopterin biosynthesis enzymes-like Family:GTP cyclohydrolase I 45 c2cfuA_ not modelled 24.3 16 PDB header:hydrolase Chain: A: PDB Molecule:sdsa1; PDBTitle: crystal structure of sdsa1, an alkylsulfatase from2 pseudomonas aeruginosa, in complex with 1-decane-sulfonic-3 acid. 46 d2oara1 not modelled 23.9 14 Fold:Gated mechanosensitive channel Superfamily:Gated mechanosensitive channel Family:Gated mechanosensitive channel 47 d1wf3a2 not modelled 23.7 21 Fold:Alpha-lytic protease prodomain-like Superfamily:Prokaryotic type KH domain (KH-domain type II) Family:Prokaryotic type KH domain (KH-domain type II) 48 d1afia_ not modelled 23.5 19 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 49 d2qifa1 not modelled 23.3 17 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 50 d1st6a5 not modelled 22.1 35 Fold:Four-helical up-and-down bundle Superfamily:alpha-catenin/vinculin-like Family:alpha-catenin/vinculin 51 d1lwub1 not modelled 21.9 17 Fold:Fibrinogen C-terminal domain-like Superfamily:Fibrinogen C-terminal domain-like Family:Fibrinogen C-terminal domain-like 52 d2a9da1 not modelled 21.8 50 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Molybdenum-containing oxidoreductases-like dimerisation domain 53 c2e9hA_ not modelled 21.7 15 PDB header:translation Chain: A: PDB Molecule:eukaryotic translation initiation factor 5; PDBTitle: solution structure of the eif-5_eif-2b domain from human2 eukaryotic translation initiation factor 5 54 d1lwuc1 not modelled 21.6 32 Fold:Fibrinogen C-terminal domain-like Superfamily:Fibrinogen C-terminal domain-like Family:Fibrinogen C-terminal domain-like 55 c3a0bk_ not modelled 21.4 33 PDB header:electron transport Chain: K: PDB Molecule:photosystem ii reaction center protein k; PDBTitle: crystal structure of br-substituted photosystem ii complex 56 d1m1jc1 not modelled 21.3 35 Fold:Fibrinogen C-terminal domain-like Superfamily:Fibrinogen C-terminal domain-like Family:Fibrinogen C-terminal domain-like 57 c2j61B_ not modelled 20.6 30 PDB header:lectin Chain: B: PDB Molecule:ficolin-2; PDBTitle: l-ficolin complexed to n-acetylglucosamine (forme c) 58 d1l0wa2 not modelled 20.6 19 Fold:DCoH-like Superfamily:GAD domain-like Family:GAD domain 59 d2axti1 not modelled 20.5 17 Fold:Single transmembrane helix Superfamily:Photosystem II reaction center protein I, PsbI Family:PsbI-like 60 d1h3da2 not modelled 20.4 40 Fold:Ferredoxin-like Superfamily:GlnB-like Family:ATP phosphoribosyltransferase (ATP-PRTase, HisG), regulatory C-terminal domain 61 c2hpcF_ not modelled 20.2 35 PDB header:blood clotting Chain: F: PDB Molecule:fibrinogen, gamma polypeptide; PDBTitle: crystal structure of fragment d from human fibrinogen complexed with2 gly-pro-arg-pro-amide. 62 c3e6qL_ not modelled 20.1 19 PDB header:isomerase Chain: L: PDB Molecule:putative 5-carboxymethyl-2-hydroxymuconate isomerase; PDBTitle: putative 5-carboxymethyl-2-hydroxymuconate isomerase from pseudomonas2 aeruginosa. 63 d1t4aa_ not modelled 20.0 21 Fold:PurS-like Superfamily:PurS-like Family:PurS subunit of FGAM synthetase 64 c3dxsX_ not modelled 20.0 17 PDB header:hydrolase Chain: X: PDB Molecule:copper-transporting atpase ran1; PDBTitle: crystal structure of a copper binding domain from hma7, a p-2 type atpase 65 d1s6ua_ not modelled 19.7 7 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 66 c2ofhX_ not modelled 19.6 10 PDB header:hydrolase, membrane protein Chain: X: PDB Molecule:zinc-transporting atpase; PDBTitle: solution structure of the n-terminal domain of the zinc(ii) atpase2 ziaa in its apo form 67 c3mp7A_ not modelled 19.2 18 PDB header:protein transport Chain: A: PDB Molecule:preprotein translocase subunit secy; PDBTitle: lateral opening of a translocon upon entry of protein suggests the2 mechanism of insertion into membranes 68 d2aw0a_ not modelled 19.1 10 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 69 c1deqF_ not modelled 19.0 29 PDB header: PDB COMPND: 70 c3bvhC_ not modelled 18.7 38 PDB header:blood clotting Chain: C: PDB Molecule:fibrinogen gamma chain; PDBTitle: crystal structure of recombinant gammad364a fibrinogen fragment d with2 the peptide ligand gly-pro-arg-pro-amide 71 c3p2aA_ not modelled 18.6 13 PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin-like protein; PDBTitle: crystal structure of thioredoxin 2 from yersinia pestis 72 d1p6ta2 not modelled 18.0 17 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 73 c1y3kA_ not modelled 17.9 7 PDB header:hydrolase Chain: A: PDB Molecule:copper-transporting atpase 1; PDBTitle: solution structure of the apo form of the fifth domain of2 menkes protein 74 d1f9pa_ not modelled 17.8 7 Fold:IL8-like Superfamily:Interleukin 8-like chemokines Family:Interleukin 8-like chemokines 75 d1nkta3 not modelled 17.7 22 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 76 d2bj7a1 not modelled 17.7 16 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:CopG-like 77 c1d1rA_ not modelled 17.6 32 PDB header:structural genomics Chain: A: PDB Molecule:hypothetical 11.4 kd protein ycih in pyrf-osmb PDBTitle: nmr solution structure of the product of the e. coli ycih2 gene. 78 d1d1ra_ not modelled 17.6 32 Fold:eIF1-like Superfamily:eIF1-like Family:eIF1-like 79 c3p2aB_ not modelled 17.5 13 PDB header:oxidoreductase Chain: B: PDB Molecule:putative thioredoxin-like protein; PDBTitle: crystal structure of thioredoxin 2 from yersinia pestis 80 c2hnhA_ not modelled 16.7 30 PDB header:transferase Chain: A: PDB Molecule:dna polymerase iii alpha subunit; PDBTitle: crystal structure of the catalytic alpha subunit of e. coli2 replicative dna polymerase iii 81 c2fhjD_ not modelled 16.7 22 PDB header:transferase Chain: D: PDB Molecule:formylmethanofuran--tetrahydromethanopterin PDBTitle: crystal structure of formylmethanofuran:2 tetrahydromethanopterin formyltransferase in complex with3 its coenzymes 82 d1xfla_ not modelled 16.5 11 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 83 c2yx5A_ not modelled 16.5 23 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0062 protein mj1593; PDBTitle: crystal structure of methanocaldococcus jannaschii purs, one of the2 subunits of formylglycinamide ribonucleotide amidotransferase in the3 purine biosynthetic pathway 84 d1re3b1 not modelled 16.4 26 Fold:Fibrinogen C-terminal domain-like Superfamily:Fibrinogen C-terminal domain-like Family:Fibrinogen C-terminal domain-like 85 d1r9ja3 not modelled 16.2 16 Fold:TK C-terminal domain-like Superfamily:TK C-terminal domain-like Family:Transketolase C-terminal domain-like 86 d1h7sa2 not modelled 16.0 26 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain 87 c2ci2I_ not modelled 15.9 19 PDB header:proteinase inhibitor (chymotrypsin) Chain: I: PDB Molecule:chymotrypsin inhibitor 2; PDBTitle: crystal and molecular structure of the serine proteinase2 inhibitor ci-2 from barley seeds 88 d2p02a3 not modelled 15.9 31 Fold:S-adenosylmethionine synthetase Superfamily:S-adenosylmethionine synthetase Family:S-adenosylmethionine synthetase 89 c2vimA_ not modelled 15.6 13 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: x-ray structure of fasciola hepatica thioredoxin 90 d1bkna2 not modelled 15.4 26 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain 91 d1syra_ not modelled 15.4 27 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 92 c3dgpB_ not modelled 15.3 19 PDB header:transcription Chain: B: PDB Molecule:rna polymerase ii transcription factor b subunit 5; PDBTitle: crystal structure of the complex between tfb5 and the c-terminal2 domain of tfb2 93 d1otga_ not modelled 15.1 14 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) 94 c2j5zA_ not modelled 15.1 35 PDB header:lectin Chain: A: PDB Molecule:ficolin-3; PDBTitle: h-ficolin complexed to galactose 95 c2x7iA_ not modelled 15.1 11 PDB header:transferase Chain: A: PDB Molecule:mevalonate kinase; PDBTitle: crystal structure of mevalonate kinase from methicillin-2 resistant staphylococcus aureus mrsa252 96 d1wpla_ not modelled 15.0 10 Fold:T-fold Superfamily:Tetrahydrobiopterin biosynthesis enzymes-like Family:GTP cyclohydrolase I 97 c2kncA_ not modelled 15.0 15 PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex 98 d1tvxb_ not modelled 14.9 7 Fold:IL8-like Superfamily:Interleukin 8-like chemokines Family:Interleukin 8-like chemokines 99 c1is7F_ not modelled 14.9 10 PDB header:hydrolase/protein binding Chain: F: PDB Molecule:gtp cyclohydrolase i; PDBTitle: crystal structure of rat gtpchi/gfrp stimulatory complex

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0