Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0AEC5
DateThu Jan 5 11:23:00 GMT 2012
Unique Job IDd424f9ddcc5b7e54

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2c2aA_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:sensor histidine kinase;
PDBTitle: structure of the entire cytoplasmic portion of a sensor2 histidine kinase protein
Confidence and coverage
Confidence:100.0% Coverage: 25%
234 residues ( 25% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
670 residues ( 73%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDAGASIIEPLAVSTEYGM
Secondary structure 




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??


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   .........70.........80.........90.........100.........110.........120
Sequence  SLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFHLDPSSMQLGSNVPFPRQL
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?????????????????????
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   .........130.........140.........150.........160.........170.........180
Sequence  TVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYIALELDLKSVRLQQYKEIFIS
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   .........190.........200.........210.........220.........230.........240
Sequence  SVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGI
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   .........250.........260.........270.........280.........290.........300
Sequence  NSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANM
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   .........310.........320.........330.........340.........350.........360
Sequence  SHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLAIINDVLDFSKLEAGKLI
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   .........370.........380.........390.........400.........410.........420
Sequence  LESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPDNVIGDPLRLQQIITNLVGNA
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   .........430.........440.........450.........460.........470.........480
Sequence  IKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHG
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   .........490.........500.........510.........520.........530.........540
Sequence  GTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNIIIEGPSTQCLAGKRLA
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   .........550.........560.........570.........580.........590.........600
Sequence  YVEPNSAAAQCTLDILSETPLEVVYSPTFSALPPAHYDMMLLGIAVTFREPLTMQHERLA
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?
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   .........610.........620.........630.........640.........650.........660
Sequence  KAVSMTDFLMLALPCHAQVNAEKLKQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPV
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   .........670.........680.........690.........700.........710.........720
Sequence  TDESKLAMTVMAVDDNPANLKLIGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQ
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   .........730.........740.........750.........760.........770.........780
Sequence  MPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNL
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   .........790.........800.........810.........820.........830.........840
Sequence  LLRYKPGSGISSRVVTPEVNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEV
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   .........850.........860.........870.........880.........890.........900
Sequence  RNKVEEQLVGENPEGLVDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELL
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   .........910........
Sequence  ELLDEMDNVAREASKILG
Secondary structure 

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??
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2c2a chain A

3D model

Region: 275 - 520
Aligned: 234
Modelled: 246
Confidence: 100.0%
Identity: 29%
PDB header:transferase
Chain: A: PDB Molecule:sensor histidine kinase;
PDBTitle: structure of the entire cytoplasmic portion of a sensor2 histidine kinase protein

Phyre2

PDB 3d36 chain B

3D model

Region: 291 - 519
Aligned: 213
Modelled: 229
Confidence: 100.0%
Identity: 25%
PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:sporulation kinase b;
PDBTitle: how to switch off a histidine kinase: crystal structure of2 geobacillus stearothermophilus kinb with the inhibitor sda

Phyre2

PDB 2q8f chain A

3D model

Region: 264 - 528
Aligned: 258
Modelled: 261
Confidence: 100.0%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 1;
PDBTitle: structure of pyruvate dehydrogenase kinase isoform 1

Phyre2

PDB 3d2r chain B

3D model

Region: 265 - 542
Aligned: 271
Modelled: 278
Confidence: 100.0%
Identity: 15%
PDB header:transferase
Chain: B: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 4;
PDBTitle: crystal structure of pyruvate dehydrogenase kinase isoform 4 in2 complex with adp

Phyre2

PDB 2bu8 chain A

3D model

Region: 264 - 532
Aligned: 260
Modelled: 269
Confidence: 100.0%
Identity: 15%
PDB header:transferase
Chain: A: PDB Molecule:pyruvate dehydrogenase kinase isoenzyme 2;
PDBTitle: crystal structures of human pyruvate dehydrogenase kinase 22 containing physiological and synthetic ligands

Phyre2

PDB 1y8o chain A

3D model

Region: 265 - 528
Aligned: 252
Modelled: 264
Confidence: 100.0%
Identity: 15%
PDB header:transferase
Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 3;
PDBTitle: crystal structure of the pdk3-l2 complex

Phyre2

PDB 1gjv chain A

3D model

Region: 293 - 523
Aligned: 220
Modelled: 231
Confidence: 100.0%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:[3-methyl-2-oxobutanoate dehydrogenase
PDBTitle: branched-chain alpha-ketoacid dehydrogenase kinase (bck)2 complxed with atp-gamma-s

Phyre2

PDB 2ayx chain A

3D model

Region: 532 - 785
Aligned: 239
Modelled: 254
Confidence: 100.0%
Identity: 22%
PDB header:transferase
Chain: A: PDB Molecule:sensor kinase protein rcsc;
PDBTitle: solution structure of the e.coli rcsc c-terminus (residues2 700-949) containing linker region and phosphoreceiver3 domain

Phyre2

PDB 3luf chain B

3D model

Region: 536 - 785
Aligned: 235
Modelled: 250
Confidence: 100.0%
Identity: 16%
PDB header:signaling protein
Chain: B: PDB Molecule:two-component system response regulator/ggdef
PDBTitle: structure of probable two-component system response2 regulator/ggdef domain protein

Phyre2

PDB 3a0r chain A

3D model

Region: 286 - 523
Aligned: 216
Modelled: 238
Confidence: 100.0%
Identity: 28%
PDB header:transferase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of histidine kinase thka (tm1359) in complex with2 response regulator protein trra (tm1360)

Phyre2

PDB 2c2a chain A domain 2

3D model

Region: 360 - 520
Aligned: 151
Modelled: 161
Confidence: 100.0%
Identity: 27%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: Histidine kinase

Phyre2

PDB 1b3q chain A

3D model

Region: 301 - 520
Aligned: 207
Modelled: 220
Confidence: 100.0%
Identity: 15%
PDB header:transferase
Chain: A: PDB Molecule:protein (chemotaxis protein chea);
PDBTitle: crystal structure of chea-289, a signal transducing histidine kinase

Phyre2

PDB 3a0t chain A

3D model

Region: 361 - 523
Aligned: 152
Modelled: 163
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: catalytic domain of histidine kinase thka (tm1359) in2 complex with adp and mg ion (trigonal)

Phyre2

PDB 1gkz chain A domain 2

3D model

Region: 363 - 523
Aligned: 153
Modelled: 161
Confidence: 100.0%
Identity: 20%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: alpha-ketoacid dehydrogenase kinase, C-terminal domain

Phyre2

PDB 1id0 chain A

3D model

Region: 363 - 519
Aligned: 145
Modelled: 157
Confidence: 100.0%
Identity: 19%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: Histidine kinase

Phyre2

PDB 3bre chain A

3D model

Region: 668 - 785
Aligned: 118
Modelled: 118
Confidence: 100.0%
Identity: 25%
PDB header:signaling protein
Chain: A: PDB Molecule:probable two-component response regulator;
PDBTitle: crystal structure of p.aeruginosa pa3702

Phyre2

PDB 1w25 chain B

3D model

Region: 668 - 785
Aligned: 118
Modelled: 118
Confidence: 100.0%
Identity: 31%
PDB header:signaling protein
Chain: B: PDB Molecule:stalked-cell differentiation controlling protein;
PDBTitle: response regulator pled in complex with c-digmp

Phyre2

PDB 1jm6 chain A domain 2

3D model

Region: 364 - 528
Aligned: 158
Modelled: 165
Confidence: 100.0%
Identity: 16%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: alpha-ketoacid dehydrogenase kinase, C-terminal domain

Phyre2

PDB 1bxd chain A

3D model

Region: 356 - 529
Aligned: 160
Modelled: 174
Confidence: 99.9%
Identity: 24%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: Histidine kinase

Phyre2

PDB 3jz3 chain B

3D model

Region: 331 - 517
Aligned: 149
Modelled: 158
Confidence: 99.9%
Identity: 24%
PDB header:transferase
Chain: B: PDB Molecule:sensor protein qsec;
PDBTitle: structure of the cytoplasmic segment of histidine kinase qsec

Phyre2

PDB 3r0j chain A

3D model

Region: 666 - 811
Aligned: 143
Modelled: 141
Confidence: 99.9%
Identity: 22%
PDB header:dna binding protein
Chain: A: PDB Molecule:possible two component system response transcriptional
PDBTitle: structure of phop from mycobacterium tuberculosis

Phyre2

PDB 3dzd chain A

3D model

Region: 668 - 865
Aligned: 177
Modelled: 176
Confidence: 99.9%
Identity: 21%
PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator (ntrc family);
PDBTitle: crystal structure of sigma54 activator ntrc4 in the inactive2 state

Phyre2

PDB 3iqt chain A

3D model

Region: 796 - 918
Aligned: 123
Modelled: 119
Confidence: 99.8%
Identity: 94%
PDB header:transferase
Chain: A: PDB Molecule:signal transduction histidine-protein kinase bara;
PDBTitle: structure of the hpt domain of sensor protein bara from escherichia2 coli cft073.

Phyre2

PDB 3zrw chain B

3D model

Region: 201 - 351
Aligned: 107
Modelled: 107
Confidence: 99.5%
Identity: 29%
PDB header:signaling protein
Chain: B: PDB Molecule:af1503 protein, osmolarity sensor protein envz;
PDBTitle: the structure of the dimeric hamp-dhp fusion a291v mutant

Phyre2
1

c2c2aA_
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c3d36B_
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c2q8fA_
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c3d2rB_
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c2bu8A_
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c1y8oA_
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c1gjvA_
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c2ayxA_
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c3lufB_
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c3a0rA_
11

d2c2aa2
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c1b3qA_
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c3a0tA_
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d1gkza2
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d1id0a_
16

c3breA_
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c1w25B_
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d1jm6a2
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d1bxda_
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c3jz3B_
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c3r0jA_
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c3dzdA_
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c3iqtA_
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c3zrwB_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2c2aA_



100.0 29 PDB header:transferase
Chain: A: PDB Molecule:sensor histidine kinase;
PDBTitle: structure of the entire cytoplasmic portion of a sensor2 histidine kinase protein
2c3d36B_



100.0 25 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:sporulation kinase b;
PDBTitle: how to switch off a histidine kinase: crystal structure of2 geobacillus stearothermophilus kinb with the inhibitor sda
3c2q8fA_



100.0 17 PDB header:transferase
Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 1;
PDBTitle: structure of pyruvate dehydrogenase kinase isoform 1
4c3d2rB_



100.0 15 PDB header:transferase
Chain: B: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 4;
PDBTitle: crystal structure of pyruvate dehydrogenase kinase isoform 4 in2 complex with adp
5c2bu8A_



100.0 15 PDB header:transferase
Chain: A: PDB Molecule:pyruvate dehydrogenase kinase isoenzyme 2;
PDBTitle: crystal structures of human pyruvate dehydrogenase kinase 22 containing physiological and synthetic ligands
6c1y8oA_



100.0 15 PDB header:transferase
Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 3;
PDBTitle: crystal structure of the pdk3-l2 complex
7c1gjvA_



100.0 17 PDB header:transferase
Chain: A: PDB Molecule:[3-methyl-2-oxobutanoate dehydrogenase
PDBTitle: branched-chain alpha-ketoacid dehydrogenase kinase (bck)2 complxed with atp-gamma-s
8c2ayxA_



100.0 22 PDB header:transferase
Chain: A: PDB Molecule:sensor kinase protein rcsc;
PDBTitle: solution structure of the e.coli rcsc c-terminus (residues2 700-949) containing linker region and phosphoreceiver3 domain
9c3lufB_



100.0 16 PDB header:signaling protein
Chain: B: PDB Molecule:two-component system response regulator/ggdef
PDBTitle: structure of probable two-component system response2 regulator/ggdef domain protein
10c3a0rA_



100.0 28 PDB header:transferase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of histidine kinase thka (tm1359) in complex with2 response regulator protein trra (tm1360)
11d2c2aa2



100.0 27 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:Histidine kinase
12c1b3qA_



100.0 15 PDB header:transferase
Chain: A: PDB Molecule:protein (chemotaxis protein chea);
PDBTitle: crystal structure of chea-289, a signal transducing histidine kinase
13c3a0tA_



100.0 26 PDB header:transferase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: catalytic domain of histidine kinase thka (tm1359) in2 complex with adp and mg ion (trigonal)
14d1gkza2



100.0 20 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:alpha-ketoacid dehydrogenase kinase, C-terminal domain
15d1id0a_



100.0 19 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:Histidine kinase
16c3breA_



100.0 25 PDB header:signaling protein
Chain: A: PDB Molecule:probable two-component response regulator;
PDBTitle: crystal structure of p.aeruginosa pa3702
17c1w25B_



100.0 31 PDB header:signaling protein
Chain: B: PDB Molecule:stalked-cell differentiation controlling protein;
PDBTitle: response regulator pled in complex with c-digmp
18d1jm6a2



100.0 16 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:alpha-ketoacid dehydrogenase kinase, C-terminal domain
19d1bxda_



99.9 24 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:Histidine kinase
20c3jz3B_



99.9 24 PDB header:transferase
Chain: B: PDB Molecule:sensor protein qsec;
PDBTitle: structure of the cytoplasmic segment of histidine kinase qsec
21c3i5aA_



not modelled 99.9 25 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator/ggdef domain protein;
PDBTitle: crystal structure of full-length wpsr from pseudomonas syringae
22c3eq2A_



not modelled 99.9 27 PDB header:signaling protein
Chain: A: PDB Molecule:probable two-component response regulator;
PDBTitle: structure of hexagonal crystal form of pseudomonas2 aeruginosa rssb
23d1k66a_



not modelled 99.9 23 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
24c3gt7A_



not modelled 99.9 25 PDB header:hydrolase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of signal receiver domain of signal2 transduction histidine kinase from syntrophus3 aciditrophicus
25d1w25a1



not modelled 99.9 32 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
26c2zayA_



not modelled 99.9 26 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator receiver protein;
PDBTitle: crystal structure of response regulator from desulfuromonas2 acetoxidans
27c3t6kB_



not modelled 99.9 26 PDB header:signaling protein
Chain: B: PDB Molecule:response regulator receiver;
PDBTitle: crystal structure of a hypothetical response regulator (caur_3799)2 from chloroflexus aurantiacus j-10-fl at 1.86 a resolution
28c2ch4A_



not modelled 99.9 17 PDB header:transferase/chemotaxis
Chain: A: PDB Molecule:chemotaxis protein chea;
PDBTitle: complex between bacterial chemotaxis histidine kinase chea2 domains p4 and p5 and receptor-adaptor protein chew
29d1heya_



not modelled 99.9 23 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
30d1ysra1



not modelled 99.9 22 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:Histidine kinase
31d2ayxa1



not modelled 99.9 31 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
32c3h1gA_



not modelled 99.9 22 PDB header:signaling protein
Chain: A: PDB Molecule:chemotaxis protein chey homolog;
PDBTitle: crystal structure of chey mutant t84a of helicobacter pylori
33c3mmnA_



not modelled 99.9 35 PDB header:transferase
Chain: A: PDB Molecule:histidine kinase homolog;
PDBTitle: crystal structure of the receiver domain of the histidine kinase cki12 from arabidopsis thaliana complexed with mg2+
34c3gl9B_



not modelled 99.9 24 PDB header:signaling protein
Chain: B: PDB Molecule:response regulator;
PDBTitle: the structure of a histidine kinase-response regulator2 complex sheds light into two-component signaling and3 reveals a novel cis autophosphorylation mechanism
35d2r25b1



not modelled 99.9 28 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
36d1p6qa_



not modelled 99.9 23 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
37d1mb3a_



not modelled 99.9 30 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
38c3cnbC_



not modelled 99.9 17 PDB header:dna binding protein
Chain: C: PDB Molecule:dna-binding response regulator, merr family;
PDBTitle: crystal structure of signal receiver domain of dna binding response2 regulator protein (merr) from colwellia psychrerythraea 34h
39d1jbea_



not modelled 99.9 25 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
40c2qvgA_



not modelled 99.9 19 PDB header:transferase
Chain: A: PDB Molecule:two component response regulator;
PDBTitle: the crystal structure of a two-component response regulator2 from legionella pneumophila
41d1u0sy_



not modelled 99.9 26 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
42d1peya_



not modelled 99.9 22 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
43d2pl1a1



not modelled 99.9 22 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
44d1zesa1



not modelled 99.9 21 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
45d1ny5a1



not modelled 99.9 23 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
46c3lteH_



not modelled 99.9 22 PDB header:transcription
Chain: H: PDB Molecule:response regulator;
PDBTitle: crystal structure of response regulator (signal receiver domain) from2 bermanella marisrubri
47d1i3ca_



not modelled 99.9 19 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
48d1qkka_



not modelled 99.9 26 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
49d1i58a_



not modelled 99.9 19 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:Histidine kinase
50d1s8na_



not modelled 99.9 26 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
51c1ny5A_



not modelled 99.9 23 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulator (ntrc family);
PDBTitle: crystal structure of sigm54 activator (aaa+ atpase) in the inactive2 state
52c3c3mA_



not modelled 99.9 26 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator receiver protein;
PDBTitle: crystal structure of the n-terminal domain of response regulator2 receiver protein from methanoculleus marisnigri jr1
53d1mvoa_



not modelled 99.9 26 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
54c3cfyA_



not modelled 99.9 26 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative luxo repressor protein;
PDBTitle: crystal structure of signal receiver domain of putative luxo2 repressor protein from vibrio parahaemolyticus
55c3khtA_



not modelled 99.9 24 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator;
PDBTitle: crystal structure of response regulator from hahella chejuensis
56c3r0jA_



99.9 22 PDB header:dna binding protein
Chain: A: PDB Molecule:possible two component system response transcriptional
PDBTitle: structure of phop from mycobacterium tuberculosis
57c2zwmA_



not modelled 99.9 27 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulatory protein yycf;
PDBTitle: crystal structure of yycf receiver domain from bacillus2 subtilis
58c3n0rA_



not modelled 99.9 28 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator;
PDBTitle: structure of the phyr stress response regulator at 1.25 angstrom2 resolution
59d2a9pa1



not modelled 99.9 22 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
60c3hebB_



not modelled 99.9 20 PDB header:transcription regulator
Chain: B: PDB Molecule:response regulator receiver domain protein (chey);
PDBTitle: crystal structure of response regulator receiver domain from2 rhodospirillum rubrum
61c3cg4A_



not modelled 99.9 25 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:response regulator receiver domain protein (chey-like);
PDBTitle: crystal structure of response regulator receiver domain protein (chey-2 like) from methanospirillum hungatei jf-1
62d1zh2a1



not modelled 99.9 28 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
63c3nhzA_



not modelled 99.9 22 PDB header:dna binding protein
Chain: A: PDB Molecule:two component system transcriptional regulator mtra;
PDBTitle: structure of n-terminal domain of mtra
64d1dcfa_



not modelled 99.9 18 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:Receiver domain of the ethylene receptor
65c3m6mF_



not modelled 99.9 24 PDB header:lyase/transferase
Chain: F: PDB Molecule:sensory/regulatory protein rpfc;
PDBTitle: crystal structure of rpff complexed with rec domain of rpfc
66d1ys7a2



not modelled 99.9 26 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
67c3i42A_



not modelled 99.9 23 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:response regulator receiver domain protein (chey-
PDBTitle: structure of response regulator receiver domain (chey-like)2 from methylobacillus flagellatus
68c2qzjC_



not modelled 99.9 22 PDB header:transcription
Chain: C: PDB Molecule:two-component response regulator;
PDBTitle: crystal structure of a two-component response regulator from2 clostridium difficile
69d1dbwa_



not modelled 99.9 23 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
70c3ilhA_



not modelled 99.9 20 PDB header:transcription regulator
Chain: A: PDB Molecule:two component response regulator;
PDBTitle: crystal structure of two component response regulator from cytophaga2 hutchinsonii
71c2rjnA_



not modelled 99.9 23 PDB header:hydrolase
Chain: A: PDB Molecule:response regulator receiver:metal-dependent
PDBTitle: crystal structure of an uncharacterized protein q2bku2 from2 neptuniibacter caesariensis
72d1zgza1



not modelled 99.9 23 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
73c2qr3A_



not modelled 99.9 23 PDB header:transcription
Chain: A: PDB Molecule:two-component system response regulator;
PDBTitle: crystal structure of the n-terminal signal receiver domain of two-2 component system response regulator from bacteroides fragilis
74c3jteA_



not modelled 99.9 22 PDB header:protein binding
Chain: A: PDB Molecule:response regulator receiver protein;
PDBTitle: crystal structure of response regulator receiver domain2 protein from clostridium thermocellum
75d1yioa2



not modelled 99.9 25 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
76c3hdvB_



not modelled 99.9 19 PDB header:transcription regulator
Chain: B: PDB Molecule:response regulator;
PDBTitle: crystal structure of response regulator receiver protein from2 pseudomonas putida
77c3b2nA_



not modelled 99.9 20 PDB header:transcription
Chain: A: PDB Molecule:uncharacterized protein q99uf4;
PDBTitle: crystal structure of dna-binding response regulator, luxr family, from2 staphylococcus aureus
78c3hdgE_



not modelled 99.9 21 PDB header:structural genomics, unknown function
Chain: E: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of the n-terminal domain of an2 uncharacterized protein (ws1339) from wolinella3 succinogenes
79c3hv2B_



not modelled 99.9 23 PDB header:signaling protein
Chain: B: PDB Molecule:response regulator/hd domain protein;
PDBTitle: crystal structure of signal receiver domain of hd domain-2 containing protein from pseudomonas fluorescens pf-5
80d1xhfa1



not modelled 99.9 17 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
81d1a04a2



not modelled 99.9 25 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
82c3luaA_



not modelled 99.9 22 PDB header:transcription regulator
Chain: A: PDB Molecule:response regulator receiver protein;
PDBTitle: crystal structure of a signal receiver domain of two component signal2 transduction (histidine kinase) from clostridium thermocellum
83c2gwrA_



not modelled 99.9 20 PDB header:signaling protein
Chain: A: PDB Molecule:dna-binding response regulator mtra;
PDBTitle: crystal structure of the response regulator protein mtra from2 mycobacterium tuberculosis
84d1kgsa2



not modelled 99.9 26 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
85c2jrlA_



not modelled 99.9 26 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulator (ntrc family);
PDBTitle: solution structure of the beryllofluoride-activated ntrc4 receiver2 domain dimer
86d1krwa_



not modelled 99.9 25 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
87d1dz3a_



not modelled 99.9 23 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
88d1k68a_



not modelled 99.9 22 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
89c3dzdA_



99.9 21 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator (ntrc family);
PDBTitle: crystal structure of sigma54 activator ntrc4 in the inactive2 state
90c1ys7B_



not modelled 99.9 24 PDB header:transcription regulator
Chain: B: PDB Molecule:transcriptional regulatory protein prra;
PDBTitle: crystal structure of the response regulator protein prra comlexed with2 mg2+
91c3c97A_



not modelled 99.9 26 PDB header:signaling protein, transferase
Chain: A: PDB Molecule:signal transduction histidine kinase;
PDBTitle: crystal structure of the response regulator receiver domain2 of a signal transduction histidine kinase from aspergillus3 oryzae
92c3grcD_



not modelled 99.9 24 PDB header:transferase
Chain: D: PDB Molecule:sensor protein, kinase;
PDBTitle: crystal structure of a sensor protein from polaromonas sp.2 js666
93c3cu5B_



not modelled 99.9 22 PDB header:transcription regulator
Chain: B: PDB Molecule:two component transcriptional regulator, arac family;
PDBTitle: crystal structure of a two component transcriptional regulator arac2 from clostridium phytofermentans isdg
94c3crnA_



not modelled 99.9 25 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator receiver domain protein, chey-like;
PDBTitle: crystal structure of response regulator receiver domain protein (chey-2 like) from methanospirillum hungatei jf-1
95c2qxyB_



not modelled 99.9 19 PDB header:transcription
Chain: B: PDB Molecule:response regulator;
PDBTitle: crystal structure of a response regulator from thermotoga2 maritima
96c1a2oB_



not modelled 99.9 19 PDB header:bacterial chemotaxis
Chain: B: PDB Molecule:cheb methylesterase;
PDBTitle: structural basis for methylesterase cheb regulation by a2 phosphorylation-activated domain
97c3cg0A_



not modelled 99.9 23 PDB header:lyase
Chain: A: PDB Molecule:response regulator receiver modulated diguanylate cyclase
PDBTitle: crystal structure of signal receiver domain of modulated diguanylate2 cyclase from desulfovibrio desulfuricans g20, an example of alternate3 folding
98c3eulB_



not modelled 99.9 24 PDB header:transcription
Chain: B: PDB Molecule:possible nitrate/nitrite response transcriptional
PDBTitle: structure of the signal receiver domain of the putative2 response regulator narl from mycobacterium tuberculosis
99c2j48A_



not modelled 99.9 17 PDB header:transferase
Chain: A: PDB Molecule:two-component sensor kinase;
PDBTitle: nmr structure of the pseudo-receiver domain of the cika2 protein.
100d1w25a2



not modelled 99.9 23 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
101c3cz5B_



not modelled 99.9 23 PDB header:transcription regulator
Chain: B: PDB Molecule:two-component response regulator, luxr family;
PDBTitle: crystal structure of two-component response regulator, luxr family,2 from aurantimonas sp. si85-9a1
102c3nhmA_



not modelled 99.9 23 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator;
PDBTitle: crystal structure of a response regulator from myxococcus xanthus
103c3rqiA_



not modelled 99.9 19 PDB header:transcription
Chain: A: PDB Molecule:response regulator protein;
PDBTitle: crystal structure of a response regulator protein from burkholderia2 pseudomallei with a phosphorylated aspartic acid, calcium ion and3 citrate
104c3hzhA_



not modelled 99.9 19 PDB header:signaling protein
Chain: A: PDB Molecule:chemotaxis response regulator (chey-3);
PDBTitle: crystal structure of the chex-chey-bef3-mg+2 complex from2 borrelia burgdorferi
105c2qv0A_



not modelled 99.9 25 PDB header:transcription
Chain: A: PDB Molecule:protein mrke;
PDBTitle: crystal structure of the response regulatory domain of2 protein mrke from klebsiella pneumoniae
106c3eodA_



not modelled 99.9 25 PDB header:signaling protein
Chain: A: PDB Molecule:protein hnr;
PDBTitle: crystal structure of n-terminal domain of e. coli rssb
107c1p2fA_



not modelled 99.9 23 PDB header:transcription
Chain: A: PDB Molecule:response regulator;
PDBTitle: crystal structure analysis of response regulator drrb, a2 thermotoga maritima ompr/phob homolog
108d2b4aa1



not modelled 99.9 21 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
109c2jk1A_



not modelled 99.9 22 PDB header:dna-binding
Chain: A: PDB Molecule:hydrogenase transcriptional regulatory protein hupr1;
PDBTitle: crystal structure of the wild-type hupr receiver domain
110d1r62a_



not modelled 99.9 24 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:Histidine kinase
111c1kgsA_



not modelled 99.9 26 PDB header:dna binding protein
Chain: A: PDB Molecule:dna binding response regulator d;
PDBTitle: crystal structure at 1.50 a of an ompr/phob homolog from thermotoga2 maritima
112c3h5iA_



not modelled 99.9 30 PDB header:transcription
Chain: A: PDB Molecule:response regulator/sensory box protein/ggdef
PDBTitle: crystal structure of the n-terminal domain of a response2 regulator/sensory box/ggdef 3-domain protein from3 carboxydothermus hydrogenoformans
113c2rdmB_



not modelled 99.9 22 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:response regulator receiver protein;
PDBTitle: crystal structure of response regulator receiver protein from2 sinorhizobium medicae wsm419
114d1qo0d_



not modelled 99.9 15 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:Positive regulator of the amidase operon AmiR
115d1p2fa2



not modelled 99.9 24 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
116c3f6cB_



not modelled 99.9 18 PDB header:dna binding protein
Chain: B: PDB Molecule:positive transcription regulator evga;
PDBTitle: crystal structure of n-terminal domain of positive transcription2 regulator evga from escherichia coli
117c3kcnA_



not modelled 99.9 20 PDB header:lyase
Chain: A: PDB Molecule:adenylate cyclase homolog;
PDBTitle: the crystal structure of adenylate cyclase from2 rhodopirellula baltica
118c3a0rB_



not modelled 99.9 18 PDB header:transferase
Chain: B: PDB Molecule:response regulator;
PDBTitle: crystal structure of histidine kinase thka (tm1359) in complex with2 response regulator protein trra (tm1360)
119c2nt3A_



not modelled 99.9 16 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator homolog;
PDBTitle: receiver domain from myxococcus xanthus social motility protein frzs2 (y102a mutant)
120d2hkja3



not modelled 99.9 22 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:DNA gyrase/MutL, N-terminal domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0