Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP77455
DateThu Jan 5 12:29:26 GMT 2012
Unique Job IDd2435275ab17b442

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2vroB_
Top template information
PDB header:oxidoreductase
Chain: B: PDB Molecule:aldehyde dehydrogenase;
PDBTitle: crystal structure of aldehyde dehydrogenase from2 burkholderia xenovorans lb400
Confidence and coverage
Confidence:100.0% Coverage: 75%
510 residues ( 75% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
673 residues ( 99%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MQQLASFLSGTWQSGRGRSRLIHHAISGEALWEVTSEGLDMAAARQFAIEKGAPALRAMT
Secondary structure 
SS confidence 
Disorder  ????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  FIERAAMLKAVAKHLLSEKERFYALSAQTGATRADSWVDIEGGIGTLFTYASLGSRELPD
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  DTLWPEDELIPLSKEGGFAARHLLTSKSGVAVHINAFNFPCWGMLEKLAPTWLGGMPAII
Secondary structure 
SS confidence 
Disorder 
??????????????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  KPATATAQLTQAMVKSIVDSGLVPEGAISLICGSAGDLLDHLDSQDVVTFTGSAATGQML
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  RVQPNIVAKSIPFTMEADSLNCCVLGEDVTPDQPEFALFIREVVREMTTKAGQKCTAIRR
Secondary structure 
SS confidence 
Disorder 
?
??
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  IIVPQALVNAVSDALVARLQKVVVGDPAQEGVKMGALVNAEQRADVQEKVNILLAAGCEI
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  RLGGQADLSAAGAFFPPTLLYCPQPDETPAVHATEAFGPVATLMPAQNQRHALQLACAGG
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  GSLAGTLVTADPQIARQFIADAARTHGRIQILNEESAKESTGHGSPLPQLVHGGPGRAGG
Secondary structure 
SS confidence 
Disorder 
?
????
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  GEELGGLRAVKHYMQRTAVQGSPTMLAAISKQWVRGAKVEEDRIHPFRKYFEELQPGDSL
Secondary structure 
SS confidence 
Disorder 
?
?
???????????
??????????
????????
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  LTPRRTMTEADIVNFACLSGDHFYAHMDKIAAAESIFGERVVHGYFVLSAAAGLFVDAGV
Secondary structure 
SS confidence 
Disorder  ???????
?????
Disorder confidence 
 
   .........610.........620.........630.........640.........650.........660
Sequence  GPVIANYGLESLRFIEPVKPGDTIQVRLTCKRKTLKKQRSAEEKPTGVVEWAVEVFNQHQ
Secondary structure 
SS confidence 
Disorder 
??????????????
Disorder confidence 
 
   .........670.........680.
Sequence  TPVALYSILTLVARQHGDFVD
Secondary structure 
SS confidence 
Disorder 
??????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2vro chain B

3D model

Region: 4 - 514
Aligned: 510
Modelled: 511
Confidence: 100.0%
Identity: 45%
PDB header:oxidoreductase
Chain: B: PDB Molecule:aldehyde dehydrogenase;
PDBTitle: crystal structure of aldehyde dehydrogenase from2 burkholderia xenovorans lb400

Phyre2

PDB 1uzb chain A

3D model

Region: 2 - 499
Aligned: 469
Modelled: 493
Confidence: 100.0%
Identity: 21%
Fold: ALDH-like
Superfamily: ALDH-like
Family: ALDH-like

Phyre2

PDB 1a4s chain A

3D model

Region: 5 - 500
Aligned: 463
Modelled: 482
Confidence: 100.0%
Identity: 24%
Fold: ALDH-like
Superfamily: ALDH-like
Family: ALDH-like

Phyre2

PDB 3ed6 chain B

3D model

Region: 5 - 499
Aligned: 463
Modelled: 480
Confidence: 100.0%
Identity: 23%
PDB header:oxidoreductase
Chain: B: PDB Molecule:betaine aldehyde dehydrogenase;
PDBTitle: 1.7 angstrom resolution crystal structure of betaine aldehyde2 dehydrogenase (betb) from staphylococcus aureus

Phyre2

PDB 3qan chain B

3D model

Region: 2 - 499
Aligned: 468
Modelled: 487
Confidence: 100.0%
Identity: 22%
PDB header:oxidoreductase
Chain: B: PDB Molecule:1-pyrroline-5-carboxylate dehydrogenase 1;
PDBTitle: crystal structure of 1-pyrroline-5-carboxylate dehydrogenase from2 bacillus halodurans

Phyre2

PDB 2jg7 chain G

3D model

Region: 2 - 500
Aligned: 466
Modelled: 486
Confidence: 100.0%
Identity: 20%
PDB header:oxidoreductase
Chain: G: PDB Molecule:antiquitin;
PDBTitle: crystal structure of seabream antiquitin and elucidation of2 its substrate specificity

Phyre2

PDB 3rh9 chain A

3D model

Region: 1 - 499
Aligned: 467
Modelled: 485
Confidence: 100.0%
Identity: 22%
PDB header:oxidoreductase
Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase (nad(p)(+));
PDBTitle: the crystal structure of oxidoreductase from marinobacter aquaeolei

Phyre2

PDB 1bxs chain A

3D model

Region: 1 - 499
Aligned: 466
Modelled: 494
Confidence: 100.0%
Identity: 22%
Fold: ALDH-like
Superfamily: ALDH-like
Family: ALDH-like

Phyre2

PDB 3iwk chain B

3D model

Region: 3 - 499
Aligned: 468
Modelled: 496
Confidence: 100.0%
Identity: 22%
PDB header:oxidoreductase
Chain: B: PDB Molecule:aminoaldehyde dehydrogenase;
PDBTitle: crystal structure of aminoaldehyde dehydrogenase 1 from2 pisum sativum (psamadh1)

Phyre2

PDB 2d4e chain B

3D model

Region: 2 - 499
Aligned: 465
Modelled: 482
Confidence: 100.0%
Identity: 20%
PDB header:oxidoreductase
Chain: B: PDB Molecule:5-carboxymethyl-2-hydroxymuconate semialdehyde
PDBTitle: crystal structure of the hpcc from thermus thermophilus hb8

Phyre2

PDB 1o9j chain A

3D model

Region: 1 - 499
Aligned: 466
Modelled: 494
Confidence: 100.0%
Identity: 22%
Fold: ALDH-like
Superfamily: ALDH-like
Family: ALDH-like

Phyre2

PDB 2o2q chain A

3D model

Region: 2 - 499
Aligned: 469
Modelled: 493
Confidence: 100.0%
Identity: 18%
PDB header:oxidoreductase
Chain: A: PDB Molecule:formyltetrahydrofolate dehydrogenase;
PDBTitle: crystal structure of the c-terminal domain of rat2 10'formyltetrahydrofolate dehydrogenase in complex with nadp

Phyre2

PDB 2ve5 chain H

3D model

Region: 1 - 500
Aligned: 468
Modelled: 491
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: H: PDB Molecule:betaine aldehyde dehydrogenase;
PDBTitle: crystallographic structure of betaine aldehyde2 dehydrogenase from pseudomonas aeruginosa

Phyre2

PDB 1t90 chain B

3D model

Region: 1 - 499
Aligned: 468
Modelled: 491
Confidence: 100.0%
Identity: 18%
PDB header:oxidoreductase
Chain: B: PDB Molecule:probable methylmalonate-semialdehyde
PDBTitle: crystal structure of methylmalonate semialdehyde2 dehydrogenase from bacillus subtilis

Phyre2

PDB 1euh chain A

3D model

Region: 2 - 500
Aligned: 465
Modelled: 494
Confidence: 100.0%
Identity: 21%
Fold: ALDH-like
Superfamily: ALDH-like
Family: ALDH-like

Phyre2

PDB 3i44 chain A

3D model

Region: 1 - 499
Aligned: 464
Modelled: 487
Confidence: 100.0%
Identity: 20%
PDB header:oxidoreductase
Chain: A: PDB Molecule:aldehyde dehydrogenase;
PDBTitle: crystal structure of aldehyde dehydrogenase from bartonella2 henselae at 2.0a resolution

Phyre2

PDB 1o04 chain A

3D model

Region: 1 - 499
Aligned: 466
Modelled: 494
Confidence: 100.0%
Identity: 21%
Fold: ALDH-like
Superfamily: ALDH-like
Family: ALDH-like

Phyre2

PDB 1ky8 chain A

3D model

Region: 1 - 500
Aligned: 469
Modelled: 489
Confidence: 100.0%
Identity: 21%
Fold: ALDH-like
Superfamily: ALDH-like
Family: ALDH-like

Phyre2

PDB 1wnd chain A

3D model

Region: 1 - 499
Aligned: 465
Modelled: 494
Confidence: 100.0%
Identity: 23%
Fold: ALDH-like
Superfamily: ALDH-like
Family: ALDH-like

Phyre2

PDB 3ifg chain H

3D model

Region: 1 - 499
Aligned: 466
Modelled: 489
Confidence: 100.0%
Identity: 23%
PDB header:oxidoreductase
Chain: H: PDB Molecule:succinate-semialdehyde dehydrogenase (nadp+);
PDBTitle: crystal structure of succinate-semialdehyde dehydrogenase from2 burkholderia pseudomallei, part 1 of 2

Phyre2

PDB 2bi0 chain A

3D model

Region: 524 - 678
Aligned: 153
Modelled: 151
Confidence: 100.0%
Identity: 18%
PDB header:hypothetical protein
Chain: A: PDB Molecule:hypothetical protein rv0216;
PDBTitle: rv0216, a conserved hypothetical protein from mycobacterium2 tuberculosis that is essential for bacterial survival3 during infection, has a double hotdogfold

Phyre2

PDB 2bi0 chain A domain 1

3D model

Region: 524 - 676
Aligned: 151
Modelled: 148
Confidence: 100.0%
Identity: 19%
Fold: Thioesterase/thiol ester dehydrase-isomerase
Superfamily: Thioesterase/thiol ester dehydrase-isomerase
Family: MaoC-like

Phyre2

PDB 2bi0 chain A domain 2

3D model

Region: 510 - 671
Aligned: 146
Modelled: 146
Confidence: 100.0%
Identity: 20%
Fold: Thioesterase/thiol ester dehydrase-isomerase
Superfamily: Thioesterase/thiol ester dehydrase-isomerase
Family: MaoC-like

Phyre2
1
c2vroB_
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d1uzba_
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d1a4sa_
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c3ed6B_
5
c3qanB_
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c2jg7G_
7
c3rh9A_
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d1bxsa_
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c3iwkB_
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c2d4eB_
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d1o9ja_
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c2o2qA_
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c2ve5H_
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c1t90B_
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d1euha_
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c3i44A_
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d1o04a_
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d1ky8a_
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d1wnda_
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c3ifgH_
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c2bi0A_
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d2bi0a1
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d2bi0a2
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2vroB_
100.0 45 PDB header:oxidoreductase
Chain: B: PDB Molecule:aldehyde dehydrogenase;
PDBTitle: crystal structure of aldehyde dehydrogenase from2 burkholderia xenovorans lb400
2d1uzba_
100.0 21 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
3d1a4sa_
100.0 24 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
4c3ed6B_
100.0 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:betaine aldehyde dehydrogenase;
PDBTitle: 1.7 angstrom resolution crystal structure of betaine aldehyde2 dehydrogenase (betb) from staphylococcus aureus
5c3qanB_
100.0 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:1-pyrroline-5-carboxylate dehydrogenase 1;
PDBTitle: crystal structure of 1-pyrroline-5-carboxylate dehydrogenase from2 bacillus halodurans
6c2jg7G_
100.0 20 PDB header:oxidoreductase
Chain: G: PDB Molecule:antiquitin;
PDBTitle: crystal structure of seabream antiquitin and elucidation of2 its substrate specificity
7c3rh9A_
100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase (nad(p)(+));
PDBTitle: the crystal structure of oxidoreductase from marinobacter aquaeolei
8d1bxsa_
100.0 22 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
9c3iwkB_
100.0 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:aminoaldehyde dehydrogenase;
PDBTitle: crystal structure of aminoaldehyde dehydrogenase 1 from2 pisum sativum (psamadh1)
10c2d4eB_
100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:5-carboxymethyl-2-hydroxymuconate semialdehyde
PDBTitle: crystal structure of the hpcc from thermus thermophilus hb8
11d1o9ja_
100.0 22 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
12c2o2qA_
100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:formyltetrahydrofolate dehydrogenase;
PDBTitle: crystal structure of the c-terminal domain of rat2 10'formyltetrahydrofolate dehydrogenase in complex with nadp
13c2ve5H_
100.0 24 PDB header:oxidoreductase
Chain: H: PDB Molecule:betaine aldehyde dehydrogenase;
PDBTitle: crystallographic structure of betaine aldehyde2 dehydrogenase from pseudomonas aeruginosa
14c1t90B_
100.0 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:probable methylmalonate-semialdehyde
PDBTitle: crystal structure of methylmalonate semialdehyde2 dehydrogenase from bacillus subtilis
15d1euha_
100.0 21 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
16c3i44A_
100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:aldehyde dehydrogenase;
PDBTitle: crystal structure of aldehyde dehydrogenase from bartonella2 henselae at 2.0a resolution
17d1o04a_
100.0 21 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
18d1ky8a_
100.0 21 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
19d1wnda_
100.0 23 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
20c3ifgH_
100.0 23 PDB header:oxidoreductase
Chain: H: PDB Molecule:succinate-semialdehyde dehydrogenase (nadp+);
PDBTitle: crystal structure of succinate-semialdehyde dehydrogenase from2 burkholderia pseudomallei, part 1 of 2
21c3hazA_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:proline dehydrogenase;
PDBTitle: crystal structure of bifunctional proline utilization a2 (puta) protein
22d1ag8a_
not modelled 100.0 22 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
23c2w8qA_
not modelled 100.0 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase,
PDBTitle: the crystal structure of human ssadh in complex with ssa.
24c3r31A_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:betaine aldehyde dehydrogenase;
PDBTitle: crystal structure of betaine aldehyde dehydrogenase from agrobacterium2 tumefaciens
25c3b4wA_
not modelled 100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:aldehyde dehydrogenase;
PDBTitle: crystal structure of mycobacterium tuberculosis aldehyde dehydrogenase2 complexed with nad+
26c3k2wD_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: D: PDB Molecule:betaine-aldehyde dehydrogenase;
PDBTitle: crystal structure of betaine-aldehyde dehydrogenase from2 pseudoalteromonas atlantica t6c
27c3ek1C_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: C: PDB Molecule:aldehyde dehydrogenase;
PDBTitle: crystal structure of aldehyde dehydrogenase from brucella2 melitensis biovar abortus 2308
28c3prlD_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: D: PDB Molecule:nadp-dependent glyceraldehyde-3-phosphate dehydrogenase;
PDBTitle: crystal structure of nadp-dependent glyceraldehyde-3-phosphate2 dehydrogenase from bacillus halodurans c-125
29c3ju8B_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:succinylglutamic semialdehyde dehydrogenase;
PDBTitle: crystal structure of succinylglutamic semialdehyde dehydrogenase from2 pseudomonas aeruginosa.
30c3jz4C_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: C: PDB Molecule:succinate-semialdehyde dehydrogenase [nadp+];
PDBTitle: crystal structure of e. coli nadp dependent enzyme
31c2hg2A_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:aldehyde dehydrogenase a;
PDBTitle: structure of lactaldehyde dehydrogenase
32d1bi9a_
not modelled 100.0 22 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
33c3r64A_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:nad dependent benzaldehyde dehydrogenase;
PDBTitle: crystal structure of a nad-dependent benzaldehyde dehydrogenase from2 corynebacterium glutamicum
34c3efvC_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative succinate-semialdehyde dehydrogenase;
PDBTitle: crystal structure of a putative succinate-semialdehyde dehydrogenase2 from salmonella typhimurium lt2 with bound nad
35c3rosA_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:nad-dependent aldehyde dehydrogenase;
PDBTitle: crystal structure of nad-dependent aldehyde dehydrogenase from2 lactobacillus acidophilus
36c3v4cB_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:aldehyde dehydrogenase (nadp+);
PDBTitle: crystal structure of a semialdehyde dehydrogenase from sinorhizobium2 meliloti 1021
37c3pqaA_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:lactaldehyde dehydrogenase;
PDBTitle: crystal structure of glyceraldehyde-3-phosphate dehydrogenase gapn2 from methanocaldococcus jannaschii dsm 2661
38d1ez0a_
not modelled 100.0 20 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
39d1ad3a_
not modelled 100.0 19 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
40c3lnsD_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: D: PDB Molecule:benzaldehyde dehydrogenase;
PDBTitle: benzaldehyde dehydrogenase, a class 3 aldehyde dehydrogenase, with2 bound nadp+ and benzoate adduct
41c3k9dD_
not modelled 100.0 15 PDB header:oxidoreductase
Chain: D: PDB Molecule:aldehyde dehydrogenase;
PDBTitle: crystal structure of probable aldehyde dehydrogenase from listeria2 monocytogenes egd-e
42d1o20a_
not modelled 100.0 17 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
43c3my7A_
not modelled 100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:alcohol dehydrogenase/acetaldehyde dehydrogenase;
PDBTitle: the crystal structure of the acdh domain of an alcohol dehydrogenase2 from vibrio parahaemolyticus to 2.25a
44d1vlua_
not modelled 100.0 20 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
45c2h5gA_
not modelled 100.0 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:delta 1-pyrroline-5-carboxylate synthetase;
PDBTitle: crystal structure of human pyrroline-5-carboxylate synthetase
46c1vluB_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:gamma-glutamyl phosphate reductase;
PDBTitle: crystal structure of gamma-glutamyl phosphate reductase (yor323c) from2 saccharomyces cerevisiae at 2.40 a resolution
47c2bi0A_
100.0 18 PDB header:hypothetical protein
Chain: A: PDB Molecule:hypothetical protein rv0216;
PDBTitle: rv0216, a conserved hypothetical protein from mycobacterium2 tuberculosis that is essential for bacterial survival3 during infection, has a double hotdogfold
48d2bi0a1
100.0 19 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:MaoC-like
49d2bi0a2
100.0 20 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:MaoC-like
50c3exzA_
not modelled 100.0 26 PDB header:lyase
Chain: A: PDB Molecule:maoc-like dehydratase;
PDBTitle: crystal structure of the maoc-like dehydratase from rhodospirillum2 rubrum. northeast structural genomics consortium target rrr103a.
51d1q6wa_
not modelled 100.0 37 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:MaoC-like
52d2b3na1
not modelled 100.0 26 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:MaoC-like
53d1iq6a_
not modelled 99.9 25 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:MaoC-like
54d2c2ia1
not modelled 99.9 24 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:MaoC-like
55c3ir3B_
not modelled 99.9 20 PDB header:lyase
Chain: B: PDB Molecule:3-hydroxyacyl-thioester dehydratase 2;
PDBTitle: crystal structure of human 3-hydroxyacyl-thioester dehydratase 22 (htd2)
56d1pn2a2
not modelled 99.8 23 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:MaoC-like
57d1s9ca1
not modelled 99.8 20 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:MaoC-like
58c3kh8B_
not modelled 99.6 25 PDB header:lyase
Chain: B: PDB Molecule:maoc-like dehydratase;
PDBTitle: crystal structure of maoc-like dehydratase from phytophthora capsici
59c1pn2D_
not modelled 99.6 23 PDB header:lyase
Chain: D: PDB Molecule:peroxisomal hydratase-dehydrogenase-epimerase;
PDBTitle: crystal structure analysis of the selenomethionine labelled2 2-enoyl-coa hydratase 2 domain of candida tropicalis3 multifunctional enzyme type 2
60c1s9cK_
not modelled 99.6 21 PDB header:lyase
Chain: K: PDB Molecule:peroxisomal multifunctional enzyme type 2;
PDBTitle: crystal structure analysis of the 2-enoyl-coa hydratase 22 domain of human peroxisomal multifunctional enzyme type 2
61c2cdhT_
not modelled 99.6 21 PDB header:transferase
Chain: T: PDB Molecule:dehydratase;
PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution.
62c3khpB_
not modelled 99.5 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:maoc family protein;
PDBTitle: crystal structure of a possible dehydrogenase from2 mycobacterium tuberculosis at 2.3a resolution
63c3omlA_
not modelled 99.4 24 PDB header:oxidoreductase, hydrolase
Chain: A: PDB Molecule:peroxisomal multifunctional enzyme type 2, cg3415;
PDBTitle: structure of full-length peroxisomal multifunctional enzyme type 22 from drosophila melanogaster
64c2vkzH_
not modelled 99.0 17 PDB header:transferase
Chain: H: PDB Molecule:fatty acid synthase subunit beta;
PDBTitle: structure of the cerulenin-inhibited fungal fatty acid2 synthase type i multienzyme complex
65c2uvaI_
not modelled 99.0 19 PDB header:transferase
Chain: I: PDB Molecule:fatty acid synthase beta subunits;
PDBTitle: crystal structure of fatty acid synthase from thermomyces2 lanuginosus at 3.1 angstrom resolution. this file contains3 the beta subunits of the fatty acid synthase. the entire4 crystal structure consists of one heterododecameric fatty5 acid synthase and is described in remark 400
66c2f3xA_
not modelled 98.2 15 PDB header:gene regulation
Chain: A: PDB Molecule:transcription factor fapr;
PDBTitle: crystal structure of fapr (in complex with effector)- a2 global regulator of fatty acid biosynthesis in b. subtilis
67d1s9ca2
not modelled 97.8 13 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:MaoC-like
68d1z6ba1
not modelled 97.7 17 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:FabZ-like
69d1pn2a1
not modelled 97.5 10 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:MaoC-like
70c3d6xA_
not modelled 97.5 15 PDB header:lyase
Chain: A: PDB Molecule:(3r)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase;
PDBTitle: crystal structure of campylobacter jejuni fabz
71d1mkaa_
not modelled 97.4 18 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:beta-Hydroxydecanol thiol ester dehydrase
72c3gekA_
not modelled 97.4 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative thioesterase yhda;
PDBTitle: crystal structure of putative thioesterase yhda from lactococcus2 lactis. northeast structural genomics consortium target kr113
73c3qooA_
not modelled 97.4 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of hot-dog-like taci_0573 protein from2 thermanaerovibrio acidaminovorans
74d1u1za_
not modelled 97.3 17 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:FabZ-like
75d1ixla_
not modelled 97.3 27 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:PaaI/YdiI-like
76c2glvA_
not modelled 97.2 16 PDB header:lyase
Chain: A: PDB Molecule:(3r)-hydroxymyristoyl-acyl carrier protein
PDBTitle: crystal structure of (3r)-hydroxyacyl-acyl carrier protein2 dehydratase(fabz) mutant(y100a) from helicobacter pylori
77d2cy9a1
not modelled 97.0 14 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:PaaI/YdiI-like
78c3lwgB_
not modelled 97.0 19 PDB header:unknown function
Chain: B: PDB Molecule:hp0420 homologue;
PDBTitle: crystal structure of hp0420-homologue c46a from helicobacter2 felis
79c2cf2L_
not modelled 96.9 19 PDB header:transferase
Chain: L: PDB Molecule:fatty acid synthase, dh domain;
PDBTitle: architecture of mammalian fatty acid synthase
80c3bnvD_
not modelled 96.9 14 PDB header:unknown function
Chain: D: PDB Molecule:cj0977;
PDBTitle: crystal structure of cj0977, a sigma28-regulated virulence protein2 from campylobacter jejuni.
81c3esiD_
not modelled 96.8 15 PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of an uncharacterized protein from2 erwinia carotovora subsp. atroseptica. northeast3 structural genomics target ewr179
82d2h4ua1
not modelled 96.8 14 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:PaaI/YdiI-like
83c3lbeA_
not modelled 96.8 19 PDB header:unknown function
Chain: A: PDB Molecule:putative uncharacterized protein smu.793;
PDBTitle: the crystal structure of smu.793 from streptococcus mutans ua159 bound2 to acetyl coa
84d2cwza1
not modelled 96.7 14 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:TTHA0967-like
85d2f41a1
not modelled 96.6 21 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:PaaI/YdiI-like
86d2f0xa1
not modelled 96.6 14 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:PaaI/YdiI-like
87d1ylia1
not modelled 96.5 14 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:4HBT-like
88c2gvhC_
not modelled 96.4 12 PDB header:hydrolase
Chain: C: PDB Molecule:agr_l_2016p;
PDBTitle: crystal structure of acyl-coa hydrolase (15159470) from agrobacterium2 tumefaciens at 2.65 a resolution
89c2eisA_
not modelled 96.3 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein tthb207;
PDBTitle: x-ray structure of acyl-coa hydrolase-like protein, tt1379, from2 thermus thermophilus hb8
90d1q4ua_
not modelled 96.3 17 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:PaaI/YdiI-like
91d2fs2a1
not modelled 96.2 25 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:PaaI/YdiI-like
92c2qwzB_
not modelled 96.0 18 PDB header:hydrolase
Chain: B: PDB Molecule:phenylacetic acid degradation-related protein;
PDBTitle: crystal structure of a putative thioesterase (tm1040_1390) from2 silicibacter sp. tm1040 at 2.15 a resolution
93d1y7ua1
not modelled 96.0 11 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:4HBT-like
94d1vh9a_
not modelled 96.0 18 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:PaaI/YdiI-like
95c2pimA_
not modelled 95.9 22 PDB header:hydrolase
Chain: A: PDB Molecule:phenylacetic acid degradation-related protein;
PDBTitle: crystal structure of a putative thioesterase, phenylacetic acid2 degradation-related protein (reut_b4779) from ralstonia eutropha3 jmp134 at 2.20 a resolution
96c3nwzD_
not modelled 95.9 18 PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:bh2602 protein;
PDBTitle: crystal structure of bh2602 protein from bacillus halodurans with coa,2 northeast structural genomics consortium target bhr199
97d1vh5a_
not modelled 95.9 11 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:PaaI/YdiI-like
98d2gvha1
not modelled 95.9 13 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:4HBT-like
99d1wlua1
not modelled 95.9 22 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:PaaI/YdiI-like
100d2gvha2
not modelled 95.8 11 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:4HBT-like
101d1k75a_
not modelled 95.7 13 Fold:ALDH-like
Superfamily:ALDH-like
Family:L-histidinol dehydrogenase HisD
102c3f1tB_
not modelled 95.7 15 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein q9i3c8_pseae;
PDBTitle: crystal structure of the q9i3c8_pseae protein from pseudomonas2 aeruginosa. northeast structural genomics consortium target par319a.
103c3b7kA_
not modelled 95.7 14 PDB header:hydrolase
Chain: A: PDB Molecule:acyl-coenzyme a thioesterase 12;
PDBTitle: human acyl-coenzyme a thioesterase 12
104c2v1oF_
not modelled 95.6 15 PDB header:hydrolase
Chain: F: PDB Molecule:cytosolic acyl coenzyme a thioester hydrolase;
PDBTitle: crystal structure of n-terminal domain of acyl-coa2 thioesterase 7
105d1s5ua_
not modelled 95.6 11 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:4HBT-like
106c3s4kA_
not modelled 95.6 10 PDB header:hydrolase
Chain: A: PDB Molecule:putative esterase rv1847/mt1895;
PDBTitle: structure of a putative esterase rv1847/mt1895 from mycobacterium2 tuberculosis
107d2ov9a1
not modelled 95.5 14 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:PaaI/YdiI-like
108c2qq2C_
not modelled 95.5 12 PDB header:hydrolase
Chain: C: PDB Molecule:cytosolic acyl coenzyme a thioester hydrolase;
PDBTitle: crystal structure of c-terminal domain of human acyl-coa thioesterase2 7
109c3hduB_
not modelled 95.3 20 PDB header:hydrolase
Chain: B: PDB Molecule:putative thioesterase;
PDBTitle: crystal structure of a putative thioesterase (syn_01977) from2 syntrophus aciditrophicus sb at 2.50 a resolution
110d1zkia1
not modelled 95.2 10 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:PaaI/YdiI-like
111d1vpma_
not modelled 95.2 15 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:4HBT-like
112c3ck1B_
not modelled 95.0 16 PDB header:hydrolase
Chain: B: PDB Molecule:putative thioesterase;
PDBTitle: crystal structure of a putative thioesterase (reut_a2179) from2 ralstonia eutropha jmp134 at 1.74 a resolution
113c3e8pA_
not modelled 95.0 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of the protein q8e9m7 from shewanella2 oneidensis related to thioesterase superfamily. northeast3 structural genomics consortium target sor246.
114d2hboa1
not modelled 94.9 9 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:PaaI/YdiI-like
115c3e29C_
not modelled 94.9 14 PDB header:structural genomics, unknown function
Chain: C: PDB Molecule:uncharacterized protein q7we92_borbr;
PDBTitle: x-ray structure of the protein q7we92_borbr from thioesterase2 superfamily. northeast structural genomics consortium target bor214a.
116c3kuvB_
not modelled 94.7 14 PDB header:hydrolase
Chain: B: PDB Molecule:fluoroacetyl coenzyme a thioesterase;
PDBTitle: structural basis of the activity and substrate specificity of the2 fluoroacetyl-coa thioesterase flk - t42s mutant in complex with3 acetate.
117d2fuja1
not modelled 94.7 13 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:4HBT-like
118c3hm0C_
not modelled 94.6 11 PDB header:hydrolase
Chain: C: PDB Molecule:probable thioesterase;
PDBTitle: crystal structure of probable thioesterase from bartonella2 henselae
119c2prxB_
not modelled 94.5 18 PDB header:hydrolase
Chain: B: PDB Molecule:thioesterase superfamily protein;
PDBTitle: crystal structure of thioesterase superfamily protein (zp_00837258.1)2 from shewanella loihica pv-4 at 1.65 a resolution
120d1sc0a_
not modelled 94.4 16 Fold:Thioesterase/thiol ester dehydrase-isomerase
Superfamily:Thioesterase/thiol ester dehydrase-isomerase
Family:PaaI/YdiI-like

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0