Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0A924
DateThu Jan 5 11:09:13 GMT 2012
Unique Job IDcf8c9bf7fb923d61

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2akcC_
Top template information
PDB header:hydrolase
Chain: C: PDB Molecule:class a nonspecific acid phosphatase phon;
PDBTitle: crystal structure of tungstate complex of the phon protein2 from s. typhimurium
Confidence and coverage
Confidence: 99.9% Coverage: 47%
119 residues ( 47% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MRSIARRTAVGAALLLVMPVAVWISGWRWQPGEQSWLLKAAFWVTETVTQPWGVITHLIL
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   .........70.........80.........90.........100.........110.........120
Sequence  FGWFLWCLRFRIKAAFVLFAILAAAILVGQGVKSWIKDKVQEPRPFVIWLEKTHHIPVDE
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????



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   .........130.........140.........150.........160.........170.........180
Sequence  FYTLKRAERGNLVKEQLAEEKNIPQYLRSHWQKETGFAFPSGHTMFAASWALLAVGLLWP
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   .........190.........200.........210.........220.........230.........240
Sequence  RRRTLTIAILLVWATGVMGSRLLLGMHWPRDLVVATLISWALVAVATWLAQRICGPLTPP
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??????
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   .........250....
Sequence  AEENREIAQREQES
Secondary structure 


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Disorder  ??







????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2akc chain C

3D model

Region: 69 - 223
Aligned: 119
Modelled: 124
Confidence: 99.9%
Identity: 23%
PDB header:hydrolase
Chain: C: PDB Molecule:class a nonspecific acid phosphatase phon;
PDBTitle: crystal structure of tungstate complex of the phon protein2 from s. typhimurium

Phyre2

PDB 1d2t chain A

3D model

Region: 69 - 223
Aligned: 117
Modelled: 122
Confidence: 99.9%
Identity: 28%
Fold: Acid phosphatase/Vanadium-dependent haloperoxidase
Superfamily: Acid phosphatase/Vanadium-dependent haloperoxidase
Family: Type 2 phosphatidic acid phosphatase, PAP2

Phyre2

PDB 1vng chain A

3D model

Region: 77 - 211
Aligned: 105
Modelled: 110
Confidence: 98.3%
Identity: 21%
PDB header:haloperoxidase
Chain: A: PDB Molecule:vanadium chloroperoxidase;
PDBTitle: chloroperoxidase from the fungus curvularia inaequalis:2 mutant h404a

Phyre2

PDB 1vns chain A

3D model

Region: 77 - 211
Aligned: 105
Modelled: 110
Confidence: 98.3%
Identity: 22%
Fold: Acid phosphatase/Vanadium-dependent haloperoxidase
Superfamily: Acid phosphatase/Vanadium-dependent haloperoxidase
Family: Chloroperoxidase

Phyre2

PDB 1qi9 chain A

3D model

Region: 158 - 224
Aligned: 67
Modelled: 67
Confidence: 98.2%
Identity: 24%
Fold: Acid phosphatase/Vanadium-dependent haloperoxidase
Superfamily: Acid phosphatase/Vanadium-dependent haloperoxidase
Family: Haloperoxidase (bromoperoxidase)

Phyre2

PDB 1qhb chain A

3D model

Region: 130 - 224
Aligned: 95
Modelled: 95
Confidence: 97.6%
Identity: 16%
Fold: Acid phosphatase/Vanadium-dependent haloperoxidase
Superfamily: Acid phosphatase/Vanadium-dependent haloperoxidase
Family: Haloperoxidase (bromoperoxidase)

Phyre2

PDB 1up8 chain A

3D model

Region: 130 - 224
Aligned: 95
Modelled: 95
Confidence: 97.5%
Identity: 13%
Fold: Acid phosphatase/Vanadium-dependent haloperoxidase
Superfamily: Acid phosphatase/Vanadium-dependent haloperoxidase
Family: Haloperoxidase (bromoperoxidase)

Phyre2

PDB 1v54 chain D

3D model

Region: 201 - 252
Aligned: 52
Modelled: 52
Confidence: 63.8%
Identity: 15%
Fold: Single transmembrane helix
Superfamily: Mitochondrial cytochrome c oxidase subunit IV
Family: Mitochondrial cytochrome c oxidase subunit IV

Phyre2

PDB 2y69 chain Q

3D model

Region: 201 - 252
Aligned: 52
Modelled: 52
Confidence: 63.8%
Identity: 15%
PDB header:electron transport
Chain: Q: PDB Molecule:cytochrome c oxidase subunit 4 isoform 1;
PDBTitle: bovine heart cytochrome c oxidase re-refined with molecular2 oxygen

Phyre2

PDB 2jln chain A

3D model

Region: 215 - 254
Aligned: 40
Modelled: 40
Confidence: 27.8%
Identity: 10%
PDB header:membrane protein
Chain: A: PDB Molecule:mhp1;
PDBTitle: structure of mhp1, a nucleobase-cation-symport-1 family2 transporter

Phyre2

PDB 2a65 chain A domain 1

3D model

Region: 184 - 248
Aligned: 57
Modelled: 65
Confidence: 26.5%
Identity: 21%
Fold: SNF-like
Superfamily: SNF-like
Family: SNF-like

Phyre2

PDB 2knc chain B

3D model

Region: 212 - 253
Aligned: 42
Modelled: 42
Confidence: 23.7%
Identity: 12%
PDB header:cell adhesion
Chain: B: PDB Molecule:integrin beta-3;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex

Phyre2

PDB 2knc chain A

3D model

Region: 212 - 249
Aligned: 38
Modelled: 38
Confidence: 19.2%
Identity: 21%
PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-iib;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex

Phyre2

PDB 3qnq chain D

3D model

Region: 213 - 249
Aligned: 37
Modelled: 37
Confidence: 8.5%
Identity: 22%
PDB header:membrane protein, transport protein
Chain: D: PDB Molecule:pts system, cellobiose-specific iic component;
PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system

Phyre2

PDB 1l7v chain A

3D model

Region: 199 - 240
Aligned: 42
Modelled: 42
Confidence: 6.9%
Identity: 17%
Fold: ABC transporter involved in vitamin B12 uptake, BtuC
Superfamily: ABC transporter involved in vitamin B12 uptake, BtuC
Family: ABC transporter involved in vitamin B12 uptake, BtuC

Phyre2
1

c2akcC_
2

d1d2ta_
3

c1vngA_
4

d1vnsa_
5

d1qi9a_
6

d1qhba_
7

d1up8a_
8

d1v54d_
9

c2y69Q_
10

c2jlnA_
11

d2a65a1
12

c2kncB_
13

c2kncA_
14

c3qnqD_
15

d1l7va_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2akcC_



99.9 23 PDB header:hydrolase
Chain: C: PDB Molecule:class a nonspecific acid phosphatase phon;
PDBTitle: crystal structure of tungstate complex of the phon protein2 from s. typhimurium
2d1d2ta_



99.9 28 Fold:Acid phosphatase/Vanadium-dependent haloperoxidase
Superfamily:Acid phosphatase/Vanadium-dependent haloperoxidase
Family:Type 2 phosphatidic acid phosphatase, PAP2
3c1vngA_



98.3 21 PDB header:haloperoxidase
Chain: A: PDB Molecule:vanadium chloroperoxidase;
PDBTitle: chloroperoxidase from the fungus curvularia inaequalis:2 mutant h404a
4d1vnsa_



98.3 22 Fold:Acid phosphatase/Vanadium-dependent haloperoxidase
Superfamily:Acid phosphatase/Vanadium-dependent haloperoxidase
Family:Chloroperoxidase
5d1qi9a_



98.2 24 Fold:Acid phosphatase/Vanadium-dependent haloperoxidase
Superfamily:Acid phosphatase/Vanadium-dependent haloperoxidase
Family:Haloperoxidase (bromoperoxidase)
6d1qhba_



97.6 16 Fold:Acid phosphatase/Vanadium-dependent haloperoxidase
Superfamily:Acid phosphatase/Vanadium-dependent haloperoxidase
Family:Haloperoxidase (bromoperoxidase)
7d1up8a_



97.5 13 Fold:Acid phosphatase/Vanadium-dependent haloperoxidase
Superfamily:Acid phosphatase/Vanadium-dependent haloperoxidase
Family:Haloperoxidase (bromoperoxidase)
8d1v54d_



63.8 15 Fold:Single transmembrane helix
Superfamily:Mitochondrial cytochrome c oxidase subunit IV
Family:Mitochondrial cytochrome c oxidase subunit IV
9c2y69Q_



63.8 15 PDB header:electron transport
Chain: Q: PDB Molecule:cytochrome c oxidase subunit 4 isoform 1;
PDBTitle: bovine heart cytochrome c oxidase re-refined with molecular2 oxygen
10c2jlnA_



27.8 10 PDB header:membrane protein
Chain: A: PDB Molecule:mhp1;
PDBTitle: structure of mhp1, a nucleobase-cation-symport-1 family2 transporter
11d2a65a1



26.5 21 Fold:SNF-like
Superfamily:SNF-like
Family:SNF-like
12c2kncB_



23.7 12 PDB header:cell adhesion
Chain: B: PDB Molecule:integrin beta-3;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex
13c2kncA_



19.2 21 PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-iib;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex
14c3qnqD_



8.5 22 PDB header:membrane protein, transport protein
Chain: D: PDB Molecule:pts system, cellobiose-specific iic component;
PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system
15d1l7va_



6.9 17 Fold:ABC transporter involved in vitamin B12 uptake, BtuC
Superfamily:ABC transporter involved in vitamin B12 uptake, BtuC
Family:ABC transporter involved in vitamin B12 uptake, BtuC

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0