Phyre 2 Results for P0A924

Email	l.a.kelley@imperial.ac.uk
Description	P0A924
Date	Thu Jan 5 11:09:13 GMT 2012
Unique Job ID	cf8c9bf7fb923d61

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c2akcC_

Top template information

PDB header:hydrolase
Chain: C: PDB Molecule:class a nonspecific acid phosphatase phon;
PDBTitle: crystal structure of tungstate complex of the phon protein2 from s. typhimurium

Confidence and coverage

Confidence:

99.9%

Coverage:

47%

119 residues ( 47% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.

You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M R S I A R R T A V G A A L L L V M P V A V W I S G W R W Q P G E Q S W L L K A A F W V T E T V T Q P W G V I T H L I L

Secondary structure

SS confidence

Disorder ?
?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence F G W F L W C L R F R I K A A F V L F A I L A A A I L V G Q G V K S W I K D K V Q E P R P F V I W L E K T H H I P V D E

Secondary structure

SS confidence

Disorder
? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence F Y T L K R A E R G N L V K E Q L A E E K N I P Q Y L R S H W Q K E T G F A F P S G H T M F A A S W A L L A V G L L W P

Secondary structure

SS confidence

Disorder
?
? ?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence R R R T L T I A I L L V W A T G V M G S R L L L G M H W P R D L V V A T L I S W A L V A V A T W L A Q R I C G P L T P P

Secondary structure

SS confidence

Disorder
? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 250 . . . .

Sequence A E E N R E I A Q R E Q E S

Secondary structure

SS confidence

Disorder ? ?
? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 2akc chain C

Region: 69 - 223
Aligned: 119
Modelled: 124
Confidence: 99.9%
Identity: 23%
PDB header:hydrolase
Chain: C: PDB Molecule:class a nonspecific acid phosphatase phon;
PDBTitle: crystal structure of tungstate complex of the phon protein2 from s. typhimurium

Phyre2

PDB 1d2t chain A

Region: 69 - 223
Aligned: 117
Modelled: 122
Confidence: 99.9%
Identity: 28%
Fold: Acid phosphatase/Vanadium-dependent haloperoxidase
Superfamily: Acid phosphatase/Vanadium-dependent haloperoxidase
Family: Type 2 phosphatidic acid phosphatase, PAP2

Phyre2

PDB 1vng chain A

Region: 77 - 211
Aligned: 105
Modelled: 110
Confidence: 98.3%
Identity: 21%
PDB header:haloperoxidase
Chain: A: PDB Molecule:vanadium chloroperoxidase;
PDBTitle: chloroperoxidase from the fungus curvularia inaequalis:2 mutant h404a

Phyre2

PDB 1vns chain A

Region: 77 - 211
Aligned: 105
Modelled: 110
Confidence: 98.3%
Identity: 22%
Fold: Acid phosphatase/Vanadium-dependent haloperoxidase
Superfamily: Acid phosphatase/Vanadium-dependent haloperoxidase
Family: Chloroperoxidase

Phyre2

PDB 1qi9 chain A

Region: 158 - 224
Aligned: 67
Modelled: 67
Confidence: 98.2%
Identity: 24%
Fold: Acid phosphatase/Vanadium-dependent haloperoxidase
Superfamily: Acid phosphatase/Vanadium-dependent haloperoxidase
Family: Haloperoxidase (bromoperoxidase)

Phyre2

PDB 1qhb chain A

Region: 130 - 224
Aligned: 95
Modelled: 95
Confidence: 97.6%
Identity: 16%
Fold: Acid phosphatase/Vanadium-dependent haloperoxidase
Superfamily: Acid phosphatase/Vanadium-dependent haloperoxidase
Family: Haloperoxidase (bromoperoxidase)

Phyre2

PDB 1up8 chain A

Region: 130 - 224
Aligned: 95
Modelled: 95
Confidence: 97.5%
Identity: 13%
Fold: Acid phosphatase/Vanadium-dependent haloperoxidase
Superfamily: Acid phosphatase/Vanadium-dependent haloperoxidase
Family: Haloperoxidase (bromoperoxidase)

Phyre2

PDB 1v54 chain D

Region: 201 - 252
Aligned: 52
Modelled: 52
Confidence: 63.8%
Identity: 15%
Fold: Single transmembrane helix
Superfamily: Mitochondrial cytochrome c oxidase subunit IV
Family: Mitochondrial cytochrome c oxidase subunit IV

Phyre2

PDB 2y69 chain Q

Region: 201 - 252
Aligned: 52
Modelled: 52
Confidence: 63.8%
Identity: 15%
PDB header:electron transport
Chain: Q: PDB Molecule:cytochrome c oxidase subunit 4 isoform 1;
PDBTitle: bovine heart cytochrome c oxidase re-refined with molecular2 oxygen

Phyre2

PDB 2jln chain A

Region: 215 - 254
Aligned: 40
Modelled: 40
Confidence: 27.8%
Identity: 10%
PDB header:membrane protein
Chain: A: PDB Molecule:mhp1;
PDBTitle: structure of mhp1, a nucleobase-cation-symport-1 family2 transporter

Phyre2

PDB 2a65 chain A domain 1

Region: 184 - 248
Aligned: 57
Modelled: 65
Confidence: 26.5%
Identity: 21%
Fold: SNF-like
Superfamily: SNF-like
Family: SNF-like

Phyre2

PDB 2knc chain B

Region: 212 - 253
Aligned: 42
Modelled: 42
Confidence: 23.7%
Identity: 12%
PDB header:cell adhesion
Chain: B: PDB Molecule:integrin beta-3;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex

Phyre2

PDB 2knc chain A

Region: 212 - 249
Aligned: 38
Modelled: 38
Confidence: 19.2%
Identity: 21%
PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-iib;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex

Phyre2

PDB 3qnq chain D

Region: 213 - 249
Aligned: 37
Modelled: 37
Confidence: 8.5%
Identity: 22%
PDB header:membrane protein, transport protein
Chain: D: PDB Molecule:pts system, cellobiose-specific iic component;
PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system

Phyre2

PDB 1l7v chain A

Region: 199 - 240
Aligned: 42
Modelled: 42
Confidence: 6.9%
Identity: 17%
Fold: ABC transporter involved in vitamin B12 uptake, BtuC
Superfamily: ABC transporter involved in vitamin B12 uptake, BtuC
Family: ABC transporter involved in vitamin B12 uptake, BtuC

Phyre2

Detailed template information

#	Template	Alignment Coverage	3D Model	Confidence	% i.d.	Template Information

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server

Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]

If you use the binding site predictions from 3DLigandSite, please also cite:

3DLigandSite: predicting ligand-binding sites using similar structures.

Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]

Imperial College London

Lawrence Kelley, Benjamin Jefferys

Disclaimer

Terms and Conditions

Component software

Template detection: HHpred 1.51

Secondary structure prediction: Psi-pred 2.5

Disorder prediction: Disopred 2.4

Transmembrane prediction: Memsat_SVM

Multi-template modelling and ab initio: Poing 1.0

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	R	S	I	A	R	R	T	A	V	G	A	A	L	L	L	V	M	P	V	A	V	W	I	S	G	W	R	W	Q	P	G	E	Q	S	W	L	L	K	A	A	F	W	V	T	E	T	V	T	Q	P	W	G	V	I	T	H	L	I	L
Secondary structure
SS confidence
Disorder	?																																	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	F	G	W	F	L	W	C	L	R	F	R	I	K	A	A	F	V	L	F	A	I	L	A	A	A	I	L	V	G	Q	G	V	K	S	W	I	K	D	K	V	Q	E	P	R	P	F	V	I	W	L	E	K	T	H	H	I	P	V	D	E
Secondary structure
SS confidence
Disorder																																																					?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence	F	Y	T	L	K	R	A	E	R	G	N	L	V	K	E	Q	L	A	E	E	K	N	I	P	Q	Y	L	R	S	H	W	Q	K	E	T	G	F	A	F	P	S	G	H	T	M	F	A	A	S	W	A	L	L	A	V	G	L	L	W	P
Secondary structure
SS confidence
Disorder																			?																?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence	R	R	R	T	L	T	I	A	I	L	L	V	W	A	T	G	V	M	G	S	R	L	L	L	G	M	H	W	P	R	D	L	V	V	A	T	L	I	S	W	A	L	V	A	V	A	T	W	L	A	Q	R	I	C	G	P	L	T	P	P
Secondary structure
SS confidence
Disorder																																																							?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	250	.	.	.	.
Sequence	A	E	E	N	R	E	I	A	Q	R	E	Q	E	S
Secondary structure
SS confidence
Disorder	?	?									?	?	?	?
Disorder confidence