Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	T	T	W	F	V	G	A	D	W	L	A	E	H	I	D	D	P	E	I	Q	I	I	D	A	R	M	A	S	P	G	Q	E	D	R	N	V	A	Q	E	Y	L	N	G	H	I	P	G	A	V	F	F	D	I	E	A	L	S	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?																										?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		H	T	S	P	L	P	H	M	L	P	R	P	E	T	F	A	V	A	M	R	E	L	G	V	N	Q	D	K	H	L	I	V	Y	D	E	G	N	L	F	S	A	P	R	A	W	W	M	L	R	T	F	G	V	E	K	V	S	I	L	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	G	L	A	G	W	Q	R	D	D	L	L	L	E	E	G	A	V	E	L	P	E	G	E	F	N	A	A	F	N	P	E	A	V	V	K	V	T	D	V	L	L	A	S	H	E	N	T	A	Q	I	I	D	A	R	P	A	A	R	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		N	A	E	V	D	E	P	R	P	G	L	R	R	G	H	I	P	G	A	L	N	V	P	W	T	E	L	V	R	E	G	E	L	K	T	T	D	E	L	D	A	I	F	F	G	R	G	V	S	Y	D	K	P	I	I	V	S	C	G	S
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?																				?		?													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.
Sequence		G	V	T	A	A	V	V	L	L	A	L	A	T	L	D	V	P	N	V	K	L	Y	D	G	A	W	S	E	W	G	A	R	A	D	L	P	V	E	P	V	K
Secondary structure
SS confidence
Disorder																																?	?		?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1urh chain A Region: 3 - 268 Aligned: 261 Modelled: 266 Confidence: 100.0% Identity: 98% PDB header:transferase Chain: A: PDB Molecule:3-mercaptopyruvate sulfurtransferase; PDBTitle: the "rhodanese" fold and catalytic mechanism of2 3-mercaptopyruvate sulfotransferases: crystal structure3 of ssea from escherichia coli Phyre2 PDB 3olh chain A Region: 4 - 278 Aligned: 270 Modelled: 275 Confidence: 100.0% Identity: 39% PDB header:transferase Chain: A: PDB Molecule:3-mercaptopyruvate sulfurtransferase; PDBTitle: human 3-mercaptopyruvate sulfurtransferase Phyre2 PDB 1e0c chain A Region: 2 - 278 Aligned: 263 Modelled: 274 Confidence: 100.0% Identity: 28% PDB header:sulfurtransferase Chain: A: PDB Molecule:sulfurtransferase; PDBTitle: sulfurtransferase from azotobacter vinelandii Phyre2 PDB 1boi chain A Region: 6 - 278 Aligned: 270 Modelled: 273 Confidence: 100.0% Identity: 36% PDB header:transferase Chain: A: PDB Molecule:rhodanese; PDBTitle: n-terminally truncated rhodanese Phyre2 PDB 3aax chain B Region: 2 - 278 Aligned: 265 Modelled: 277 Confidence: 100.0% Identity: 29% PDB header:transferase Chain: B: PDB Molecule:putative thiosulfate sulfurtransferase; PDBTitle: crystal structure of probable thiosulfate sulfurtransferase2 cysa3 (rv3117) from mycobacterium tuberculosis: monoclinic3 form Phyre2 PDB 3hzu chain A Region: 4 - 278 Aligned: 262 Modelled: 264 Confidence: 100.0% Identity: 26% PDB header:transferase Chain: A: PDB Molecule:thiosulfate sulfurtransferase ssea; PDBTitle: crystal structure of probable thiosulfate sulfurtransferase ssea2 (rhodanese) from mycobacterium tuberculosis Phyre2 PDB 3ipp chain A Region: 6 - 278 Aligned: 259 Modelled: 273 Confidence: 100.0% Identity: 24% PDB header:transferase Chain: A: PDB Molecule:putative thiosulfate sulfurtransferase ynje; PDBTitle: crystal structure of sulfur-free ynje Phyre2 PDB 1okg chain A Region: 4 - 278 Aligned: 266 Modelled: 274 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: A: PDB Molecule:possible 3-mercaptopyruvate sulfurtransferase; PDBTitle: 3-mercaptopyruvate sulfurtransferase from leishmania major Phyre2 PDB 1uar chain A Region: 4 - 278 Aligned: 261 Modelled: 275 Confidence: 100.0% Identity: 29% PDB header:transferase Chain: A: PDB Molecule:rhodanese; PDBTitle: crystal structure of rhodanese from thermus thermophilus hb8 Phyre2 PDB 2eg4 chain B Region: 18 - 279 Aligned: 226 Modelled: 262 Confidence: 100.0% Identity: 23% PDB header:transferase Chain: B: PDB Molecule:probable thiosulfate sulfurtransferase; PDBTitle: crystal structure of probable thiosulfate sulfurtransferase Phyre2 PDB 1yt8 chain A Region: 6 - 278 Aligned: 221 Modelled: 244 Confidence: 100.0% Identity: 23% PDB header:transferase Chain: A: PDB Molecule:thiosulfate sulfurtransferase; PDBTitle: crystal structure of thiosulfate sulfurtransferase from pseudomonas2 aeruginosa Phyre2 PDB 3tp9 chain B Region: 5 - 278 Aligned: 201 Modelled: 230 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase and rhodanese domain protein; PDBTitle: crystal structure of alicyclobacillus acidocaldarius protein with2 beta-lactamase and rhodanese domains Phyre2 PDB 1urh chain A domain 1 Region: 3 - 149 Aligned: 147 Modelled: 147 Confidence: 100.0% Identity: 100% Fold: Rhodanese/Cell cycle control phosphatase Superfamily: Rhodanese/Cell cycle control phosphatase Family: Multidomain sulfurtransferase (rhodanese) Phyre2 PDB 1rhs chain A domain 1 Region: 4 - 142 Aligned: 137 Modelled: 139 Confidence: 100.0% Identity: 39% Fold: Rhodanese/Cell cycle control phosphatase Superfamily: Rhodanese/Cell cycle control phosphatase Family: Multidomain sulfurtransferase (rhodanese) Phyre2 PDB 1uar chain A domain 1 Region: 2 - 152 Aligned: 140 Modelled: 151 Confidence: 99.9% Identity: 26% Fold: Rhodanese/Cell cycle control phosphatase Superfamily: Rhodanese/Cell cycle control phosphatase Family: Multidomain sulfurtransferase (rhodanese) Phyre2 PDB 1okg chain A domain 1 Region: 1 - 152 Aligned: 147 Modelled: 152 Confidence: 99.9% Identity: 18% Fold: Rhodanese/Cell cycle control phosphatase Superfamily: Rhodanese/Cell cycle control phosphatase Family: Multidomain sulfurtransferase (rhodanese) Phyre2 PDB 1e0c chain A domain 1 Region: 2 - 141 Aligned: 130 Modelled: 140 Confidence: 99.9% Identity: 28% Fold: Rhodanese/Cell cycle control phosphatase Superfamily: Rhodanese/Cell cycle control phosphatase Family: Multidomain sulfurtransferase (rhodanese) Phyre2 PDB 1uar chain A domain 2 Region: 156 - 278 Aligned: 120 Modelled: 123 Confidence: 99.9% Identity: 33% Fold: Rhodanese/Cell cycle control phosphatase Superfamily: Rhodanese/Cell cycle control phosphatase Family: Multidomain sulfurtransferase (rhodanese) Phyre2 PDB 1okg chain A domain 2 Region: 163 - 278 Aligned: 116 Modelled: 115 Confidence: 99.9% Identity: 32% Fold: Rhodanese/Cell cycle control phosphatase Superfamily: Rhodanese/Cell cycle control phosphatase Family: Multidomain sulfurtransferase (rhodanese) Phyre2 PDB 1e0c chain A domain 2 Region: 143 - 278 Aligned: 132 Modelled: 136 Confidence: 99.9% Identity: 28% Fold: Rhodanese/Cell cycle control phosphatase Superfamily: Rhodanese/Cell cycle control phosphatase Family: Multidomain sulfurtransferase (rhodanese) Phyre2 PDB 3t38 chain B Region: 216 - 279 Aligned: 59 Modelled: 59 Confidence: 59.3% Identity: 15% PDB header:oxidoreductase Chain: B: PDB Molecule:arsenate reductase; PDBTitle: corynebacterium glutamicum thioredoxin-dependent arsenate reductase2 cg_arsc1' Phyre2 1 c1urhA_ 2 c3olhA_ 3 c1e0cA_ 4 c1boiA_ 5 c3aaxB_ 6 c3hzuA_ 7 c3ippA_ 8 c1okgA_ 9 c1uarA_ 10 c2eg4B_ 11 c1yt8A_ 12 c3tp9B_ 13 d1urha1 14 d1rhsa1 15 d1uara1 16 d1okga1 17 d1e0ca1 18 d1uara2 19 d1okga2 20 d1e0ca2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 c3t38B_ 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1urhA_ 100.0 98 PDB header:transferase Chain: A: PDB Molecule:3-mercaptopyruvate sulfurtransferase; PDBTitle: the "rhodanese" fold and catalytic mechanism of2 3-mercaptopyruvate sulfotransferases: crystal structure3 of ssea from escherichia coli 2 c3olhA_ 100.0 39 PDB header:transferase Chain: A: PDB Molecule:3-mercaptopyruvate sulfurtransferase; PDBTitle: human 3-mercaptopyruvate sulfurtransferase 3 c1e0cA_ 100.0 28 PDB header:sulfurtransferase Chain: A: PDB Molecule:sulfurtransferase; PDBTitle: sulfurtransferase from azotobacter vinelandii 4 c1boiA_ 100.0 36 PDB header:transferase Chain: A: PDB Molecule:rhodanese; PDBTitle: n-terminally truncated rhodanese 5 c3aaxB_ 100.0 29 PDB header:transferase Chain: B: PDB Molecule:putative thiosulfate sulfurtransferase; PDBTitle: crystal structure of probable thiosulfate sulfurtransferase2 cysa3 (rv3117) from mycobacterium tuberculosis: monoclinic3 form 6 c3hzuA_ 100.0 26 PDB header:transferase Chain: A: PDB Molecule:thiosulfate sulfurtransferase ssea; PDBTitle: crystal structure of probable thiosulfate sulfurtransferase ssea2 (rhodanese) from mycobacterium tuberculosis 7 c3ippA_ 100.0 24 PDB header:transferase Chain: A: PDB Molecule:putative thiosulfate sulfurtransferase ynje; PDBTitle: crystal structure of sulfur-free ynje 8 c1okgA_ 100.0 27 PDB header:transferase Chain: A: PDB Molecule:possible 3-mercaptopyruvate sulfurtransferase; PDBTitle: 3-mercaptopyruvate sulfurtransferase from leishmania major 9 c1uarA_ 100.0 29 PDB header:transferase Chain: A: PDB Molecule:rhodanese; PDBTitle: crystal structure of rhodanese from thermus thermophilus hb8 10 c2eg4B_ 100.0 23 PDB header:transferase Chain: B: PDB Molecule:probable thiosulfate sulfurtransferase; PDBTitle: crystal structure of probable thiosulfate sulfurtransferase 11 c1yt8A_ 100.0 23 PDB header:transferase Chain: A: PDB Molecule:thiosulfate sulfurtransferase; PDBTitle: crystal structure of thiosulfate sulfurtransferase from pseudomonas2 aeruginosa 12 c3tp9B_ 100.0 21 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase and rhodanese domain protein; PDBTitle: crystal structure of alicyclobacillus acidocaldarius protein with2 beta-lactamase and rhodanese domains 13 d1urha1 100.0 100 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 14 d1rhsa1 100.0 39 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 15 d1uara1 99.9 26 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 16 d1okga1 99.9 18 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 17 d1e0ca1 99.9 28 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 18 d1uara2 99.9 33 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 19 d1okga2 99.9 32 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 20 d1e0ca2 99.9 28 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 21 d1rhsa2 not modelled 99.9 31 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 22 d1urha2 not modelled 99.9 96 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 23 d1yt8a3 not modelled 99.8 24 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 24 c3d1pA_ not modelled 99.8 20 PDB header:transferase Chain: A: PDB Molecule:putative thiosulfate sulfurtransferase yor285w; PDBTitle: atomic resolution structure of uncharacterized protein from2 saccharomyces cerevisiae 25 c3ilmD_ not modelled 99.8 31 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:alr3790 protein; PDBTitle: crystal structure of the alr3790 protein from anabaena sp. northeast2 structural genomics consortium target nsr437h 26 d1yt8a1 not modelled 99.8 27 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 27 c3nhvE_ not modelled 99.8 25 PDB header:structural genomics, unknown function Chain: E: PDB Molecule:bh2092 protein; PDBTitle: crystal structure of bh2092 protein from bacillus halodurans,2 northeast structural genomics consortium target bhr228f 28 c2hhgA_ not modelled 99.8 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein rpa3614; PDBTitle: structure of protein of unknown function rpa3614, possible tyrosine2 phosphatase, from rhodopseudomonas palustris cga009 29 c3f4aA_ not modelled 99.8 18 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein ygr203w; PDBTitle: structure of ygr203w, a yeast protein tyrosine phosphatase2 of the rhodanese family 30 d1tq1a_ not modelled 99.8 28 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Single-domain sulfurtransferase 31 d1yt8a4 not modelled 99.8 19 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 32 c3emeA_ not modelled 99.8 23 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:rhodanese-like domain protein; PDBTitle: crystal structure of rhodanese-like domain protein from2 staphylococcus aureus 33 d1t3ka_ not modelled 99.8 24 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Cell cycle control phosphatase, catalytic domain 34 c3gk5A_ not modelled 99.8 25 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized rhodanese-related protein PDBTitle: crystal structure of rhodanese-related protein (tvg0868615)2 from thermoplasma volcanium, northeast structural genomics3 consortium target tvr109a 35 d1qxna_ not modelled 99.8 19 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Single-domain sulfurtransferase 36 c3i2vA_ not modelled 99.7 26 PDB header:transferase Chain: A: PDB Molecule:adenylyltransferase and sulfurtransferase mocs3; PDBTitle: crystal structure of human mocs3 rhodanese-like domain 37 c3g5jA_ not modelled 99.7 17 PDB header:nucleotide binding protein Chain: A: PDB Molecule:putative atp/gtp binding protein; PDBTitle: crystal structure of n-terminal domain of putative atp/gtp binding2 protein from clostridium difficile 630 38 d1gmxa_ not modelled 99.7 22 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Single-domain sulfurtransferase 39 d1yt8a2 not modelled 99.7 24 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 40 c3fojA_ not modelled 99.7 25 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of ssp1007 from staphylococcus2 saprophyticus subsp. saprophyticus. northeast structural3 genomics target syr101a. 41 c3k9rA_ not modelled 99.7 36 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:alr3790 protein; PDBTitle: x-ray structure of the rhodanese-like domain of the alr3790 protein2 from anabaena sp. northeast structural genomics consortium target3 nsr437c. 42 c2fsxA_ not modelled 99.7 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:cog0607: rhodanese-related sulfurtransferase; PDBTitle: crystal structure of rv0390 from m. tuberculosis 43 c2dcqA_ not modelled 99.7 14 PDB header:unknown function Chain: A: PDB Molecule:putative protein at4g01050; PDBTitle: fully automated nmr structure determination of the2 rhodanese homology domain at4g01050(175-295) from3 arabidopsis thaliana 44 c3icrA_ not modelled 99.7 27 PDB header:oxidoreductase Chain: A: PDB Molecule:coenzyme a-disulfide reductase; PDBTitle: crystal structure of oxidized bacillus anthracis coadr-rhd 45 c2k0zA_ not modelled 99.7 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein hp1203; PDBTitle: solution nmr structure of protein hp1203 from helicobacter pylori2 26695. northeast structural genomics consortium (nesg) target3 pt1/ontario center for structural proteomics target hp1203 46 c3ntaA_ not modelled 99.7 23 PDB header:oxidoreductase Chain: A: PDB Molecule:fad-dependent pyridine nucleotide-disulphide PDBTitle: structure of the shewanella loihica pv-4 nadh-dependent persulfide2 reductase 47 c2j6pF_ not modelled 99.7 20 PDB header:oxidoreductase Chain: F: PDB Molecule:sb(v)-as(v) reductase; PDBTitle: structure of as-sb reductase from leishmania major 48 c2jtqA_ not modelled 99.7 18 PDB header:transferase Chain: A: PDB Molecule:phage shock protein e; PDBTitle: rhodanese from e.coli 49 c2vswB_ not modelled 99.6 21 PDB header:hydrolase Chain: B: PDB Molecule:dual specificity protein phosphatase 16; PDBTitle: the structure of the rhodanese domain of the human dual2 specificity phosphatase 16 50 d1whba_ not modelled 99.6 17 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Ubiquitin carboxyl-terminal hydrolase 8, USP8 51 d1c25a_ not modelled 99.6 22 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Cell cycle control phosphatase, catalytic domain 52 d1ymka1 not modelled 99.6 24 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Cell cycle control phosphatase, catalytic domain 53 c2oucB_ not modelled 99.5 22 PDB header:hydrolase Chain: B: PDB Molecule:dual specificity protein phosphatase 10; PDBTitle: crystal structure of the map kinase binding domain of mkp5 54 d2gwfa1 not modelled 99.5 18 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Ubiquitin carboxyl-terminal hydrolase 8, USP8 55 c2uzqE_ not modelled 99.5 24 PDB header:hydrolase Chain: E: PDB Molecule:m-phase inducer phosphatase 2; PDBTitle: protein phosphatase, new crystal form 56 d1hzma_ not modelled 99.5 23 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Cell cycle control phosphatase, catalytic domain 57 c3op3A_ not modelled 99.5 24 PDB header:hydrolase Chain: A: PDB Molecule:m-phase inducer phosphatase 3; PDBTitle: crystal structure of cell division cycle 25c protein isoform a from2 homo sapiens 58 c3r2uC_ not modelled 99.4 20 PDB header:hydrolase Chain: C: PDB Molecule:metallo-beta-lactamase family protein; PDBTitle: 2.1 angstrom resolution crystal structure of metallo-beta-lactamase2 from staphylococcus aureus subsp. aureus col 59 c1wv9B_ not modelled 99.1 24 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:rhodanese homolog tt1651; PDBTitle: crystal structure of rhodanese homolog tt1651 from an2 extremely thermophilic bacterium thermus thermophilus hb8 60 c3gxgA_ not modelled 96.6 16 PDB header:hydrolase Chain: A: PDB Molecule:putative phosphatase (duf442); PDBTitle: crystal structure of putative phosphatase (duf442) (yp_001181608.1)2 from shewanella putrefaciens cn-32 at 1.60 a resolution 61 c2f46A_ not modelled 95.8 12 PDB header:hydrolase Chain: A: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of a putative phosphatase (nma1982) from neisseria2 meningitidis z2491 at 1.41 a resolution 62 c3flhC_ not modelled 95.8 24 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein lp_1913; PDBTitle: crystal structure of lp_1913 protein from lactobacillus2 plantarum,northeast structural genomics consortium target3 lpr140b 63 d1ywfa1 not modelled 95.7 17 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Mycobacterial PtpB-like 64 d1xria_ not modelled 94.2 7 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 65 c3rgqA_ not modelled 93.0 9 PDB header:hydrolase Chain: A: PDB Molecule:protein-tyrosine phosphatase mitochondrial 1; PDBTitle: crystal structure of ptpmt1 in complex with pi(5)p 66 d1vhra_ not modelled 92.8 9 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 67 c2y96A_ not modelled 90.7 17 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity phosphatase dupd1; PDBTitle: structure of human dual-specificity phosphatase 27 68 c2e0tA_ not modelled 90.7 16 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity phosphatase 26; PDBTitle: crystal structure of catalytic domain of dual specificity phosphatase2 26, ms0830 from homo sapiens 69 c1fpzF_ not modelled 90.6 8 PDB header:hydrolase Chain: F: PDB Molecule:cyclin-dependent kinase inhibitor 3; PDBTitle: crystal structure analysis of kinase associated phosphatase2 (kap) with a substitution of the catalytic site cysteine3 (cys140) to a serine 70 d1ohea2 not modelled 90.6 12 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 71 d1fpza_ not modelled 90.5 8 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 72 c2imgA_ not modelled 89.9 10 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity protein phosphatase 23; PDBTitle: crystal structure of dual specificity protein phosphatase2 23 from homo sapiens in complex with ligand malate ion 73 d1npya1 not modelled 89.4 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain 74 c1yn9B_ not modelled 89.3 18 PDB header:hydrolase Chain: B: PDB Molecule:polynucleotide 5'-phosphatase; PDBTitle: crystal structure of baculovirus rna 5'-phosphatase2 complexed with phosphate 75 c1oheA_ not modelled 88.8 13 PDB header:hydrolase Chain: A: PDB Molecule:cdc14b2 phosphatase; PDBTitle: structure of cdc14b phosphatase with a peptide ligand 76 c2gwoC_ not modelled 88.6 10 PDB header:hydrolase Chain: C: PDB Molecule:dual specificity protein phosphatase 13; PDBTitle: crystal structure of tmdp 77 c2i6oA_ not modelled 87.0 9 PDB header:hydrolase Chain: A: PDB Molecule:sulfolobus solfataricus protein tyrosine PDBTitle: crystal structure of the complex of the archaeal sulfolobus2 ptp-fold phosphatase with phosphopeptides n-g-(p)y-k-n 78 c2r0bA_ not modelled 86.7 16 PDB header:hydrolase Chain: A: PDB Molecule:serine/threonine/tyrosine-interacting protein; PDBTitle: crystal structure of human tyrosine phosphatase-like2 serine/threonine/tyrosine-interacting protein 79 c3nmeA_ not modelled 86.6 7 PDB header:hydrolase Chain: A: PDB Molecule:sex4 glucan phosphatase; PDBTitle: structure of a plant phosphatase 80 c2oz5A_ not modelled 86.2 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:phosphotyrosine protein phosphatase ptpb; PDBTitle: crystal structure of mycobacterium tuberculosis protein tyrosine2 phosphatase ptpb in complex with the specific inhibitor omts 81 d1i9sa_ not modelled 85.7 16 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 82 d1g4us2 not modelled 84.9 21 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Higher-molecular-weight phosphotyrosine protein phosphatases 83 d1d5ra2 not modelled 84.9 12 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 84 c2c46B_ not modelled 84.6 16 PDB header:transferase Chain: B: PDB Molecule:mrna capping enzyme; PDBTitle: crystal structure of the human rna guanylyltransferase and2 5'-phosphatase 85 d1oywa3 not modelled 83.8 17 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 86 c2p4dA_ not modelled 83.0 18 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity protein phosphatase; PDBTitle: structure-assisted discovery of variola major h12 phosphatase inhibitors 87 d1mkpa_ not modelled 82.4 11 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 88 d1fuka_ not modelled 82.4 8 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 89 c3s4oB_ not modelled 81.7 24 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:protein tyrosine phosphatase-like protein; PDBTitle: protein tyrosine phosphatase (putative) from leishmania major 90 c2wgpA_ not modelled 81.5 16 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity protein phosphatase 14; PDBTitle: crystal structure of human dual specificity phosphatase 14 91 c2esbA_ not modelled 81.5 14 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity protein phosphatase 18; PDBTitle: crystal structure of human dusp18 92 c2oudA_ not modelled 81.3 21 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity protein phosphatase 10; PDBTitle: crystal structure of the catalytic domain of human mkp5 93 c1wrmA_ not modelled 80.8 16 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity phosphatase 22; PDBTitle: crystal structure of jsp-1 94 c1zzwA_ not modelled 80.8 21 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity protein phosphatase 10; PDBTitle: crystal structure of catalytic domain of human map kinase2 phosphatase 5 95 c1yz4A_ not modelled 80.7 12 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity phosphatase-like 15 isoform a; PDBTitle: crystal structure of dusp15 96 c2g6zB_ not modelled 80.2 9 PDB header:hydrolase Chain: B: PDB Molecule:dual specificity protein phosphatase 5; PDBTitle: crystal structure of human dusp5 97 c2hcmA_ not modelled 80.1 21 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity protein phosphatase; PDBTitle: crystal structure of mouse putative dual specificity phosphatase2 complexed with zinc tungstate, new york structural genomics3 consortium 98 d1v3aa_ not modelled 80.0 18 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 99 c3emuA_ not modelled 79.8 21 PDB header:hydrolase Chain: A: PDB Molecule:leucine rich repeat and phosphatase domain PDBTitle: crystal structure of a leucine rich repeat and phosphatase2 domain containing protein from entamoeba histolytica 100 c2dg2D_ not modelled 78.5 21 PDB header:protein binding Chain: D: PDB Molecule:apolipoprotein a-i binding protein; PDBTitle: crystal structure of mouse apolipoprotein a-i binding2 protein 101 d1vi2a1 not modelled 77.6 14 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain 102 c2v1xB_ not modelled 77.5 18 PDB header:hydrolase Chain: B: PDB Molecule:atp-dependent dna helicase q1; PDBTitle: crystal structure of human recq-like dna helicase 103 c3i32A_ not modelled 77.4 17 PDB header:rna binding protein,hydrolase Chain: A: PDB Molecule:heat resistant rna dependent atpase; PDBTitle: dimeric structure of a hera helicase fragment including the c-terminal2 reca domain, the dimerization domain, and the rna binding domain 104 c2nz6A_ not modelled 76.0 24 PDB header:hydrolase Chain: A: PDB Molecule:receptor-type tyrosine-protein phosphatase eta; PDBTitle: crystal structure of the ptprj inactivating mutant c1239s 105 d1m3ga_ not modelled 75.1 11 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 106 c2nt2C_ not modelled 74.3 21 PDB header:hydrolase Chain: C: PDB Molecule:protein phosphatase slingshot homolog 2; PDBTitle: crystal structure of slingshot phosphatase 2 107 d1nkta4 not modelled 74.0 11 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 108 c3d3jA_ not modelled 73.4 26 PDB header:protein binding Chain: A: PDB Molecule:enhancer of mrna-decapping protein 3; PDBTitle: crystal structure of human edc3p 109 d1jzta_ not modelled 73.4 22 Fold:YjeF N-terminal domain-like Superfamily:YjeF N-terminal domain-like Family:YjeF N-terminal domain-like 110 d1rxda_ not modelled 73.3 24 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 111 c3ohgA_ not modelled 73.3 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein from duf2233 family; PDBTitle: crystal structure of a protein with unknown function from duf22332 family (bacova_00430) from bacteroides ovatus at 1.80 a resolution 112 c2j17A_ not modelled 73.2 11 PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase yil113w; PDBTitle: ptyr bound form of sdp-1 113 d1tyza_ not modelled 72.9 12 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 114 c3d3kD_ not modelled 71.1 22 PDB header:protein binding Chain: D: PDB Molecule:enhancer of mrna-decapping protein 3; PDBTitle: crystal structure of human edc3p 115 c1npyA_ not modelled 70.9 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical shikimate 5-dehydrogenase-like PDBTitle: structure of shikimate 5-dehydrogenase-like protein hi0607 116 c1g4wR_ not modelled 70.3 21 PDB header:signaling protein Chain: R: PDB Molecule:protein tyrosine phosphatase sptp; PDBTitle: crystal structure of the salmonella tyrosine phosphatase2 and gtpase activating protein sptp 117 d1a1va2 not modelled 69.4 16 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RNA helicase 118 c3s3fA_ not modelled 69.2 18 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:tyrosine-protein phosphatase 10d; PDBTitle: crystal structure of the catalytic domain of ptp10d from drosophila2 melanogaster with a small molecule inhibitor vanadate 119 c1oywA_ not modelled 69.0 16 PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent dna helicase; PDBTitle: structure of the recq catalytic core 120 d1larb1 not modelled 68.2 13 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Higher-molecular-weight phosphotyrosine protein phosphatases

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0