Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	T	T	S	F	A	K	V	A	A	L	C	G	L	L	A	L	S	G	C	A	S	K	I	T	Q	P	D	K	Y	S	G	F	L	N	N	Y	S	D	L	K	E	T	T	S	A	T	G	K	P	V	L	R	W	V	D	P	S	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																?	?	?	?	?	?	?	?	?	?	?	?	?	?	?					?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	Q	S	K	Y	D	S	I	V	W	N	P	I	T	Y	Y	P	V	P	K	P	S	T	Q	V	G	Q	K	V	L	D	K	I	L	N	Y	T	N	T	E	M	K	E	A	I	A	Q	R	K	P	L	V	T	T	A	G	P	R	S	L
Secondary structure
SS confidence
Disorder																				?	?	?	?	?	?	?	?																					?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	F	R	G	A	I	T	G	V	D	T	S	K	E	G	L	Q	F	Y	E	V	V	P	V	A	L	V	V	A	G	T	Q	M	A	T	G	H	R	T	M	D	T	R	L	Y	F	E	G	E	L	I	D	A	A	T	N	K	P	V	I
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?	?	?	?	?	?				?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.
Sequence		K	V	V	R	Q	G	E	G	K	D	L	N	N	E	S	T	P	M	A	F	E	N	I	K	Q	V	I	D	D	M	A	T	D	A	T	M	F	D	V	N	K	K
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?																	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2iqi chain A domain 1 Region: 93 - 217 Aligned: 103 Modelled: 104 Confidence: 61.4% Identity: 9% Fold: Anticodon-binding domain-like Superfamily: XCC0632-like Family: XCC0632-like Phyre2 PDB 2dzj chain A Region: 156 - 209 Aligned: 45 Modelled: 54 Confidence: 49.8% Identity: 20% PDB header:sugar binding protein Chain: A: PDB Molecule:synaptic glycoprotein sc2; PDBTitle: 2dzj/solution structure of the n-terminal ubiquitin-like2 domain in human synaptic glycoprotein sc2 Phyre2 PDB 1pn2 chain A domain 1 Region: 106 - 185 Aligned: 54 Modelled: 54 Confidence: 38.4% Identity: 4% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: MaoC-like Phyre2 PDB 3ly8 chain A Region: 150 - 216 Aligned: 55 Modelled: 67 Confidence: 20.7% Identity: 9% PDB header:signaling protein Chain: A: PDB Molecule:transcriptional activator cadc; PDBTitle: crystal structure of mutant d471e of the periplasmic domain of cadc Phyre2 PDB 2hqs chain A domain 2 Region: 157 - 214 Aligned: 46 Modelled: 58 Confidence: 15.3% Identity: 11% Fold: Anticodon-binding domain-like Superfamily: TolB, N-terminal domain Family: TolB, N-terminal domain Phyre2 PDB 3ov5 chain A Region: 203 - 216 Aligned: 14 Modelled: 14 Confidence: 14.9% Identity: 29% PDB header:protein transport Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: atomic structure of the xanthomonas citri virb7 globular domain. Phyre2 PDB 3nqy chain A Region: 170 - 182 Aligned: 13 Modelled: 13 Confidence: 12.4% Identity: 31% PDB header:hydrolase Chain: A: PDB Molecule:secreted metalloprotease mcp02; PDBTitle: crystal structure of the autoprocessed complex of vibriolysin mcp-022 with a single point mutation e346a Phyre2 PDB 2axt chain O domain 1 Region: 159 - 186 Aligned: 28 Modelled: 28 Confidence: 9.8% Identity: 7% Fold: Transmembrane beta-barrels Superfamily: OMPA-like Family: PsbO-like Phyre2 PDB 2bi0 chain A domain 1 Region: 118 - 186 Aligned: 48 Modelled: 49 Confidence: 9.2% Identity: 19% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: MaoC-like Phyre2 PDB 2l4w chain A Region: 203 - 213 Aligned: 11 Modelled: 11 Confidence: 8.5% Identity: 27% PDB header:protein transport Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: nmr structure of the xanthomonas virb7 Phyre2 PDB 1mww chain A Region: 83 - 118 Aligned: 36 Modelled: 36 Confidence: 8.0% Identity: 6% Fold: Tautomerase/MIF Superfamily: Tautomerase/MIF Family: Hypothetical protein HI1388.1 Phyre2 PDB 1yiq chain A Region: 123 - 182 Aligned: 58 Modelled: 60 Confidence: 7.9% Identity: 19% PDB header:oxidoreductase Chain: A: PDB Molecule:quinohemoprotein alcohol dehydrogenase; PDBTitle: molecular cloning and structural analysis of2 quinohemoprotein alcohol dehydrogenase adhiig from3 pseudomonas putida hk5. compariison to the other4 quinohemoprotein alcohol dehydrogenase adhiib found in the5 same microorganism. Phyre2 PDB 2cy9 chain A domain 1 Region: 157 - 182 Aligned: 26 Modelled: 26 Confidence: 6.6% Identity: 15% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 1zto chain A Region: 19 - 26 Aligned: 8 Modelled: 8 Confidence: 5.6% Identity: 50% PDB header:potassium channel Chain: A: PDB Molecule:potassium channel protein rck4; PDBTitle: inactivation gate of potassium channel rck4, nmr, 82 structures Phyre2 PDB 1pu1 chain A Region: 83 - 108 Aligned: 26 Modelled: 26 Confidence: 5.5% Identity: 19% Fold: Hypothetical protein MTH677 Superfamily: Hypothetical protein MTH677 Family: Hypothetical protein MTH677 Phyre2 PDB 3e9v chain A domain 1 Region: 83 - 118 Aligned: 35 Modelled: 36 Confidence: 5.4% Identity: 9% Fold: BTG domain-like Superfamily: BTG domain-like Family: BTG domain-like Phyre2 PDB 2rce chain I Region: 170 - 213 Aligned: 42 Modelled: 44 Confidence: 5.4% Identity: 10% PDB header:hydrolase Chain: I: PDB Molecule:protease degs; PDBTitle: dfp modified degs delta pdz Phyre2 PDB 1kb0 chain A Region: 125 - 179 Aligned: 53 Modelled: 55 Confidence: 5.3% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:quinohemoprotein alcohol dehydrogenase; PDBTitle: crystal structure of quinohemoprotein alcohol dehydrogenase from2 comamonas testosteroni Phyre2 1 d2iqia1 2 c2dzjA_ 3 d1pn2a1 4 c3ly8A_ 5 d2hqsa2 6 c3ov5A_ 7 c3nqyA_ 8 d2axto1 9 d2bi0a1 10 c2l4wA_ 11 d1mwwa_ 12 c1yiqA_ 13 d2cy9a1 14 c1ztoA_ 15 d1pu1a_ 16 d3e9va1 17 c2rceI_ 18 c1kb0A_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2iqia1 61.4 9 Fold:Anticodon-binding domain-like Superfamily:XCC0632-like Family:XCC0632-like 2 c2dzjA_ 49.8 20 PDB header:sugar binding protein Chain: A: PDB Molecule:synaptic glycoprotein sc2; PDBTitle: 2dzj/solution structure of the n-terminal ubiquitin-like2 domain in human synaptic glycoprotein sc2 3 d1pn2a1 38.4 4 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 4 c3ly8A_ 20.7 9 PDB header:signaling protein Chain: A: PDB Molecule:transcriptional activator cadc; PDBTitle: crystal structure of mutant d471e of the periplasmic domain of cadc 5 d2hqsa2 15.3 11 Fold:Anticodon-binding domain-like Superfamily:TolB, N-terminal domain Family:TolB, N-terminal domain 6 c3ov5A_ 14.9 29 PDB header:protein transport Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: atomic structure of the xanthomonas citri virb7 globular domain. 7 c3nqyA_ 12.4 31 PDB header:hydrolase Chain: A: PDB Molecule:secreted metalloprotease mcp02; PDBTitle: crystal structure of the autoprocessed complex of vibriolysin mcp-022 with a single point mutation e346a 8 d2axto1 9.8 7 Fold:Transmembrane beta-barrels Superfamily:OMPA-like Family:PsbO-like 9 d2bi0a1 9.2 19 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 10 c2l4wA_ 8.5 27 PDB header:protein transport Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: nmr structure of the xanthomonas virb7 11 d1mwwa_ 8.0 6 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:Hypothetical protein HI1388.1 12 c1yiqA_ 7.9 19 PDB header:oxidoreductase Chain: A: PDB Molecule:quinohemoprotein alcohol dehydrogenase; PDBTitle: molecular cloning and structural analysis of2 quinohemoprotein alcohol dehydrogenase adhiig from3 pseudomonas putida hk5. compariison to the other4 quinohemoprotein alcohol dehydrogenase adhiib found in the5 same microorganism. 13 d2cy9a1 6.6 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 14 c1ztoA_ 5.6 50 PDB header:potassium channel Chain: A: PDB Molecule:potassium channel protein rck4; PDBTitle: inactivation gate of potassium channel rck4, nmr, 82 structures 15 d1pu1a_ 5.5 19 Fold:Hypothetical protein MTH677 Superfamily:Hypothetical protein MTH677 Family:Hypothetical protein MTH677 16 d3e9va1 5.4 9 Fold:BTG domain-like Superfamily:BTG domain-like Family:BTG domain-like 17 c2rceI_ 5.4 10 PDB header:hydrolase Chain: I: PDB Molecule:protease degs; PDBTitle: dfp modified degs delta pdz 18 c1kb0A_ 5.3 15 PDB header:oxidoreductase Chain: A: PDB Molecule:quinohemoprotein alcohol dehydrogenase; PDBTitle: crystal structure of quinohemoprotein alcohol dehydrogenase from2 comamonas testosteroni

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0