Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	N	S	I	L	V	I	L	C	L	I	A	V	S	A	F	F	S	M	S	E	I	S	L	A	A	S	R	K	I	K	L	K	L	L	A	D	E	G	N	I	N	A	Q	R	V	L	N	M	Q	E	N	P	G	M	F	F	T	V
Secondary structure
SS confidence
Disorder		?																												?										?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	Q	I	G	L	N	A	V	A	I	L	G	G	I	V	G	D	A	A	F	S	P	A	F	H	S	L	F	S	R	Y	M	S	A	E	L	S	E	Q	L	S	F	I	L	S	F	S	L	V	T	G	M	F	I	L	F	A	D	L	T
Secondary structure
SS confidence
Disorder																																			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	K	R	I	G	M	I	A	P	E	A	V	A	L	R	I	I	N	P	M	R	F	C	L	Y	V	C	T	P	L	V	W	F	F	N	G	L	A	N	I	I	F	R	I	F	K	L	P	M	V	R	K	D	D	I	T	S	D	D	I
Secondary structure
SS confidence
Disorder																																																?		?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Y	A	V	V	E	A	G	A	L	A	G	V	L	R	K	Q	E	H	E	L	I	E	N	V	F	E	L	E	S	R	T	V	P	S	S	M	T	P	R	E	N	V	I	W	F	D	L	H	E	D	E	Q	S	L	K	N	K	V	A	E
Secondary structure
SS confidence
Disorder											?	?	?	?	?															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		H	P	H	S	K	F	L	V	C	N	E	D	I	D	H	I	I	G	Y	V	D	S	K	D	L	L	N	R	V	L	A	N	Q	S	L	A	L	N	S	G	V	Q	I	R	N	T	L	I	V	P	D	T	L	T	L	S	E	A	L	E
Secondary structure
SS confidence
Disorder																																		?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		S	F	K	T	A	G	E	D	F	A	V	I	M	N	E	Y	A	L	V	V	G	I	I	T	L	N	D	V	M	T	T	L	M	G	D	L	V	G	Q	G	L	E	E	Q	I	V	A	R	D	E	N	S	W	L	I	D	G	G	T	P
Secondary structure
SS confidence
Disorder						?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		I	D	D	V	M	R	V	L	D	I	D	E	F	P	Q	S	G	N	Y	E	T	I	G	G	F	M	M	F	M	L	R	K	I	P	K	R	T	D	S	V	K	F	A	G	Y	K	F	E	V	V	D	I	D	N	Y	R	I	D	Q	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.
Sequence		L	V	T	R	I	D	S	K	A	T	A	L	S	P	K	L	P	D	A	K	D	K	E	E	S	V	A
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3ocm chain A Region: 192 - 343 Aligned: 149 Modelled: 149 Confidence: 100.0% Identity: 21% PDB header:membrane protein Chain: A: PDB Molecule:putative membrane protein; PDBTitle: the crystal structure of a domain from a possible membrane protein of2 bordetella parapertussis Phyre2 PDB 3ocm chain B Region: 193 - 341 Aligned: 146 Modelled: 146 Confidence: 100.0% Identity: 22% PDB header:membrane protein Chain: B: PDB Molecule:putative membrane protein; PDBTitle: the crystal structure of a domain from a possible membrane protein of2 bordetella parapertussis Phyre2 PDB 3oi8 chain B Region: 175 - 329 Aligned: 153 Modelled: 155 Confidence: 100.0% Identity: 20% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of functionally unknown conserved protein domain2 from neisseria meningitidis mc58 Phyre2 PDB 3oco chain B Region: 199 - 334 Aligned: 134 Modelled: 133 Confidence: 99.9% Identity: 23% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hemolysin-like protein containing cbs domains; PDBTitle: the crystal structure of a hemolysin-like protein containing cbs2 domain of oenococcus oeni psu Phyre2 PDB 3lhh chain A Region: 211 - 337 Aligned: 125 Modelled: 127 Confidence: 99.9% Identity: 30% PDB header:membrane protein Chain: A: PDB Molecule:cbs domain protein; PDBTitle: the crystal structure of cbs domain protein from shewanella2 oneidensis mr-1. Phyre2 PDB 3lv9 chain A Region: 205 - 336 Aligned: 130 Modelled: 132 Confidence: 99.9% Identity: 22% PDB header:membrane protein Chain: A: PDB Molecule:putative transporter; PDBTitle: crystal structure of cbs domain of a putative transporter from2 clostridium difficile 630 Phyre2 PDB 3hf7 chain A Region: 209 - 334 Aligned: 126 Modelled: 126 Confidence: 99.9% Identity: 18% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized cbs-domain protein; PDBTitle: the crystal structure of a cbs-domain pair with bound amp from2 klebsiella pneumoniae to 2.75a Phyre2 PDB 3jtf chain B Region: 209 - 336 Aligned: 125 Modelled: 128 Confidence: 99.9% Identity: 30% PDB header:transport protein Chain: B: PDB Molecule:magnesium and cobalt efflux protein; PDBTitle: the cbs domain pair structure of a magnesium and cobalt efflux protein2 from bordetella parapertussis in complex with amp Phyre2 PDB 3i8n chain B Region: 208 - 333 Aligned: 125 Modelled: 126 Confidence: 99.9% Identity: 26% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp2912; PDBTitle: a domain of a conserved functionally known protein from2 vibrio parahaemolyticus rimd 2210633. Phyre2 PDB 3lfr chain B Region: 208 - 337 Aligned: 128 Modelled: 130 Confidence: 99.9% Identity: 25% PDB header:transport protein Chain: B: PDB Molecule:putative metal ion transporter; PDBTitle: the crystal structure of a cbs domain from a putative metal2 ion transporter bound to amp from pseudomonas syringae to3 1.55a Phyre2 PDB 3nqr chain D Region: 210 - 333 Aligned: 123 Modelled: 124 Confidence: 99.9% Identity: 24% PDB header:transport protein Chain: D: PDB Molecule:magnesium and cobalt efflux protein corc; PDBTitle: a putative cbs domain-containing protein from salmonella typhimurium2 lt2 Phyre2 PDB 3kxr chain A Region: 173 - 332 Aligned: 153 Modelled: 160 Confidence: 99.9% Identity: 10% PDB header:transport protein Chain: A: PDB Molecule:magnesium transporter, putative; PDBTitle: structure of the cystathionine beta-synthase pair domain of the2 putative mg2+ transporter so5017 from shewanella oneidensis mr-1. Phyre2 PDB 3ded chain B Region: 343 - 424 Aligned: 81 Modelled: 82 Confidence: 99.8% Identity: 40% PDB header:membrane protein Chain: B: PDB Molecule:probable hemolysin; PDBTitle: c-terminal domain of probable hemolysin from chromobacterium violaceum Phyre2 PDB 3ded chain A domain 1 Region: 343 - 426 Aligned: 83 Modelled: 84 Confidence: 99.8% Identity: 39% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CorC/HlyC domain-like Phyre2 PDB 1yav chain B Region: 209 - 338 Aligned: 127 Modelled: 130 Confidence: 99.8% Identity: 12% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein bsu14130; PDBTitle: crystal structure of cbs domain-containing protein ykul2 from bacillus subtilis Phyre2 PDB 2pls chain A domain 1 Region: 346 - 426 Aligned: 81 Modelled: 81 Confidence: 99.8% Identity: 33% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CorC/HlyC domain-like Phyre2 PDB 2pli chain A domain 1 Region: 343 - 426 Aligned: 82 Modelled: 84 Confidence: 99.8% Identity: 30% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CorC/HlyC domain-like Phyre2 PDB 3ctu chain B Region: 200 - 341 Aligned: 139 Modelled: 142 Confidence: 99.8% Identity: 13% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:cbs domain protein; PDBTitle: crystal structure of cbs domain protein from streptococcus2 pneumoniae tigr4 Phyre2 PDB 2yvx chain D Region: 173 - 335 Aligned: 157 Modelled: 163 Confidence: 99.8% Identity: 15% PDB header:transport protein Chain: D: PDB Molecule:mg2+ transporter mgte; PDBTitle: crystal structure of magnesium transporter mgte Phyre2 PDB 2oox chain E domain 1 Region: 192 - 338 Aligned: 147 Modelled: 147 Confidence: 99.8% Identity: 12% Fold: CBS-domain pair Superfamily: CBS-domain pair Family: CBS-domain pair Phyre2 PDB 3org chain B Region: 69 - 332 Aligned: 218 Modelled: 218 Confidence: 99.8% Identity: 14% PDB header:transport protein Chain: B: PDB Molecule:cmclc; PDBTitle: crystal structure of a eukaryotic clc transporter Phyre2 PDB 2oai chain A domain 1 Region: 341 - 424 Aligned: 78 Modelled: 76 Confidence: 99.8% Identity: 36% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CorC/HlyC domain-like Phyre2 PDB 2p4p chain A domain 1 Region: 347 - 426 Aligned: 75 Modelled: 69 Confidence: 99.7% Identity: 52% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CorC/HlyC domain-like Phyre2 1 c3ocmA_ 2 c3ocmB_ 3 c3oi8B_ 4 c3ocoB_ 5 c3lhhA_ 6 c3lv9A_ 7 c3hf7A_ 8 c3jtfB_ 9 c3i8nB_ 10 c3lfrB_ 11 c3nqrD_ 12 c3kxrA_ 13 c3dedB_ 14 d3deda1 15 c1yavB_ 16 d2plsa1 17 d2plia1 18 c3ctuB_ 19 c2yvxD_ 20 d2ooxe1 21 22 23 24 25 26 27 28 29 30 c3orgB_ 31 32 33 34 35 36 37 38 d2oaia1 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 d2p4pa1 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3ocmA_ 100.0 21 PDB header:membrane protein Chain: A: PDB Molecule:putative membrane protein; PDBTitle: the crystal structure of a domain from a possible membrane protein of2 bordetella parapertussis 2 c3ocmB_ 100.0 22 PDB header:membrane protein Chain: B: PDB Molecule:putative membrane protein; PDBTitle: the crystal structure of a domain from a possible membrane protein of2 bordetella parapertussis 3 c3oi8B_ 100.0 20 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of functionally unknown conserved protein domain2 from neisseria meningitidis mc58 4 c3ocoB_ 99.9 23 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hemolysin-like protein containing cbs domains; PDBTitle: the crystal structure of a hemolysin-like protein containing cbs2 domain of oenococcus oeni psu 5 c3lhhA_ 99.9 30 PDB header:membrane protein Chain: A: PDB Molecule:cbs domain protein; PDBTitle: the crystal structure of cbs domain protein from shewanella2 oneidensis mr-1. 6 c3lv9A_ 99.9 22 PDB header:membrane protein Chain: A: PDB Molecule:putative transporter; PDBTitle: crystal structure of cbs domain of a putative transporter from2 clostridium difficile 630 7 c3hf7A_ 99.9 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized cbs-domain protein; PDBTitle: the crystal structure of a cbs-domain pair with bound amp from2 klebsiella pneumoniae to 2.75a 8 c3jtfB_ 99.9 30 PDB header:transport protein Chain: B: PDB Molecule:magnesium and cobalt efflux protein; PDBTitle: the cbs domain pair structure of a magnesium and cobalt efflux protein2 from bordetella parapertussis in complex with amp 9 c3i8nB_ 99.9 26 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp2912; PDBTitle: a domain of a conserved functionally known protein from2 vibrio parahaemolyticus rimd 2210633. 10 c3lfrB_ 99.9 25 PDB header:transport protein Chain: B: PDB Molecule:putative metal ion transporter; PDBTitle: the crystal structure of a cbs domain from a putative metal2 ion transporter bound to amp from pseudomonas syringae to3 1.55a 11 c3nqrD_ 99.9 24 PDB header:transport protein Chain: D: PDB Molecule:magnesium and cobalt efflux protein corc; PDBTitle: a putative cbs domain-containing protein from salmonella typhimurium2 lt2 12 c3kxrA_ 99.9 10 PDB header:transport protein Chain: A: PDB Molecule:magnesium transporter, putative; PDBTitle: structure of the cystathionine beta-synthase pair domain of the2 putative mg2+ transporter so5017 from shewanella oneidensis mr-1. 13 c3dedB_ 99.8 40 PDB header:membrane protein Chain: B: PDB Molecule:probable hemolysin; PDBTitle: c-terminal domain of probable hemolysin from chromobacterium violaceum 14 d3deda1 99.8 39 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CorC/HlyC domain-like 15 c1yavB_ 99.8 12 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein bsu14130; PDBTitle: crystal structure of cbs domain-containing protein ykul2 from bacillus subtilis 16 d2plsa1 99.8 33 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CorC/HlyC domain-like 17 d2plia1 99.8 30 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CorC/HlyC domain-like 18 c3ctuB_ 99.8 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:cbs domain protein; PDBTitle: crystal structure of cbs domain protein from streptococcus2 pneumoniae tigr4 19 c2yvxD_ 99.8 15 PDB header:transport protein Chain: D: PDB Molecule:mg2+ transporter mgte; PDBTitle: crystal structure of magnesium transporter mgte 20 d2ooxe1 99.8 12 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 21 d2nqwa1 not modelled 99.8 21 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CorC/HlyC domain-like 22 d2p13a1 not modelled 99.8 24 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CorC/HlyC domain-like 23 c3llbA_ not modelled 99.8 23 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of the protein pa3983 with unknown2 function from pseudomonas aeruginosa pao1 24 d2o3ga1 not modelled 99.8 24 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CorC/HlyC domain-like 25 d2r2za1 not modelled 99.8 23 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CorC/HlyC domain-like 26 d2o1ra1 not modelled 99.8 18 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CorC/HlyC domain-like 27 c3lqnA_ not modelled 99.8 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:cbs domain protein; PDBTitle: crystal structure of cbs domain-containing protein of2 unknown function from bacillus anthracis str. ames ancestor 28 c2yvzA_ not modelled 99.8 13 PDB header:transport protein Chain: A: PDB Molecule:mg2+ transporter mgte; PDBTitle: crystal structure of magnesium transporter mgte cytosolic domain,2 mg2+-free form 29 c2emqA_ not modelled 99.8 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical conserved protein; PDBTitle: hypothetical conserved protein (gk1048) from geobacillus kaustophilus 30 c3orgB_ 99.8 14 PDB header:transport protein Chain: B: PDB Molecule:cmclc; PDBTitle: crystal structure of a eukaryotic clc transporter 31 d2nyca1 not modelled 99.8 13 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 32 c1zfjA_ not modelled 99.8 11 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes 33 c2ouxB_ not modelled 99.8 15 PDB header:transport protein Chain: B: PDB Molecule:magnesium transporter; PDBTitle: crystal structure of the soluble part of a magnesium transporter 34 d2d4za3 not modelled 99.8 15 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 35 d1yava3 not modelled 99.8 12 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 36 c2qh1B_ not modelled 99.8 15 PDB header:unknown function Chain: B: PDB Molecule:hypothetical protein ta0289; PDBTitle: structure of ta289, a cbs-rubredoxin-like protein, in its fe+2-bound2 state 37 c2d4zB_ not modelled 99.8 16 PDB header:transport protein Chain: B: PDB Molecule:chloride channel protein; PDBTitle: crystal structure of the cytoplasmic domain of the chloride channel2 clc-0 38 d2oaia1 99.8 36 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CorC/HlyC domain-like 39 d2p3ha1 not modelled 99.8 29 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CorC/HlyC domain-like 40 d2v8qe2 not modelled 99.7 11 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 41 d3ddja1 not modelled 99.7 15 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 42 d2rk5a1 not modelled 99.7 20 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CorC/HlyC domain-like 43 c3fnaA_ not modelled 99.7 12 PDB header:isomerase Chain: A: PDB Molecule:possible arabinose 5-phosphate isomerase; PDBTitle: crystal structure of the cbs pair of possible d-arabinose 5-phosphate2 isomerase yrbh from escherichia coli cft073 44 d2j9la1 not modelled 99.7 19 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 45 c3fwrB_ not modelled 99.7 13 PDB header:transcription Chain: B: PDB Molecule:yqzb protein; PDBTitle: crystal structure of the cbs domains from the bacillus subtilis ccpn2 repressor complexed with adp 46 c3pc3A_ not modelled 99.7 11 PDB header:lyase Chain: A: PDB Molecule:cg1753, isoform a; PDBTitle: full length structure of cystathionine beta-synthase from drosophila2 in complex with aminoacrylate 47 d1vr9a3 not modelled 99.7 16 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 48 d2ouxa2 not modelled 99.7 14 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 49 d2yzqa1 not modelled 99.7 12 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 50 d2ef7a1 not modelled 99.7 13 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 51 c1vr9B_ not modelled 99.7 16 PDB header:unknown function Chain: B: PDB Molecule:cbs domain protein/act domain protein; PDBTitle: crystal structure of a cbs domain pair/act domain protein (tm0892)2 from thermotoga maritima at 1.70 a resolution 52 d2riha1 not modelled 99.7 13 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 53 d2rc3a1 not modelled 99.7 13 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 54 d2yzia1 not modelled 99.7 19 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 55 d2v8qe1 not modelled 99.7 18 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 56 d1zfja4 not modelled 99.7 7 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 57 c2p9mD_ not modelled 99.7 20 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:hypothetical protein mj0922; PDBTitle: crystal structure of conserved hypothetical protein mj0922 from2 methanocaldococcus jannaschii dsm 2661 58 d1y5ha3 not modelled 99.7 20 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 59 d1pvma4 not modelled 99.7 15 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 60 c3gbyA_ not modelled 99.7 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein ct1051; PDBTitle: crystal structure of a protein with unknown function ct10512 from chlorobium tepidum 61 d2p4pa1 99.7 52 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CorC/HlyC domain-like 62 d1o50a3 not modelled 99.7 15 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 63 d2o16a3 not modelled 99.7 16 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 64 d1pbja3 not modelled 99.7 16 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 65 c2qlvF_ not modelled 99.7 17 PDB header:transferase/protein binding Chain: F: PDB Molecule:nuclear protein snf4; PDBTitle: crystal structure of the heterotrimer core of the s.2 cerevisiae ampk homolog snf1 66 d2ooxe2 not modelled 99.6 14 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 67 c2pfiA_ not modelled 99.6 13 PDB header:transport protein Chain: A: PDB Molecule:chloride channel protein clc-ka; PDBTitle: crystal structure of the cytoplasmic domain of the human2 chloride channel clc-ka 68 c2qr1E_ not modelled 99.6 15 PDB header:transferase Chain: E: PDB Molecule:protein c1556.08c; PDBTitle: crystal structure of the adenylate sensor from amp-activated protein2 kinase in complex with adp 69 d2yvxa2 not modelled 99.6 13 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 70 c2v8qE_ not modelled 99.6 18 PDB header:transferase Chain: E: PDB Molecule:5'-amp-activated protein kinase subunit gamma-1; PDBTitle: crystal structure of the regulatory fragment of mammalian2 ampk in complexes with amp 71 c3kpbA_ not modelled 99.6 14 PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein mj0100; PDBTitle: crystal structure of the cbs domain pair of protein mj01002 in complex with 5 -methylthioadenosine and s-adenosyl-l-3 methionine. 72 c3fhmD_ not modelled 99.6 15 PDB header:structural genomics, unknown function, n Chain: D: PDB Molecule:uncharacterized protein atu1752; PDBTitle: crystal structure of the cbs-domain containing protein atu1752 from2 agrobacterium tumefaciens 73 d3ddja2 not modelled 99.6 21 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 74 c3ddjA_ not modelled 99.5 23 PDB header:amp-binding protein Chain: A: PDB Molecule:cbs domain-containing protein; PDBTitle: crystal structure of a cbs domain-containing protein in complex with2 amp (sso3205) from sulfolobus solfataricus at 1.80 a resolution 75 c3kh5A_ not modelled 99.5 18 PDB header:unknown function Chain: A: PDB Molecule:protein mj1225; PDBTitle: crystal structure of protein mj1225 from methanocaldococcus2 jannaschii, a putative archaeal homolog of g-ampk. 76 c3l31B_ not modelled 99.4 21 PDB header:hydrolase Chain: B: PDB Molecule:probable manganase-dependent inorganic PDBTitle: crystal structure of the cbs and drtgg domains of the2 regulatory region of clostridium perfringens3 pyrophosphatase complexed with the inhibitor, amp 77 c2yzqA_ not modelled 99.4 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative uncharacterized protein ph1780; PDBTitle: crystal structure of uncharacterized conserved protein from2 pyrococcus horikoshii 78 d2yzqa2 not modelled 99.3 22 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 79 c3fioB_ not modelled 98.0 18 PDB header:nucleotide binding protein, metal bindin Chain: B: PDB Molecule:a cystathionine beta-synthase domain protein PDBTitle: crystal structure of a fragment of a cystathionine beta-2 synthase domain protein fused to a zn-ribbon-like domain 80 d1jcna4 not modelled 97.4 24 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 81 d1jr1a4 not modelled 97.3 22 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 82 d1udxa3 not modelled 74.8 18 Fold:Obg GTP-binding protein C-terminal domain Superfamily:Obg GTP-binding protein C-terminal domain Family:Obg GTP-binding protein C-terminal domain 83 d2pp6a1 not modelled 52.1 36 Fold:Phage tail proteins Superfamily:Phage tail proteins Family:gpFII-like 84 c2ejbA_ not modelled 40.0 11 PDB header:lyase Chain: A: PDB Molecule:probable aromatic acid decarboxylase; PDBTitle: crystal structure of phenylacrylic acid decarboxylase from2 aquifex aeolicus 85 d1pbwa_ not modelled 37.0 11 Fold:GTPase activation domain, GAP Superfamily:GTPase activation domain, GAP Family:BCR-homology GTPase activation domain (BH-domain) 86 c3hczA_ not modelled 36.3 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:possible thiol-disulfide isomerase; PDBTitle: the crystal structure of a domain of possible thiol-disulfide2 isomerase from cytophaga hutchinsonii atcc 33406. 87 c3nwuB_ not modelled 33.9 36 PDB header:hydrolase Chain: B: PDB Molecule:serine protease htra1; PDBTitle: substrate induced remodeling of the active site regulates htra12 activity 88 d1t3ta1 not modelled 33.4 14 Fold:RuvA C-terminal domain-like Superfamily:FGAM synthase PurL, linker domain Family:FGAM synthase PurL, linker domain 89 c3nziA_ not modelled 33.3 33 PDB header:hydrolase/hydrolase substrate Chain: A: PDB Molecule:serine protease htra1; PDBTitle: substrate induced remodeling of the active site regulates htra12 activity 90 d1g8fa1 not modelled 33.2 17 Fold:PUA domain-like Superfamily:PUA domain-like Family:ATP sulfurylase N-terminal domain 91 d1lcya2 not modelled 32.7 29 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Prokaryotic proteases 92 c3ia1A_ not modelled 31.5 19 PDB header:oxidoreductase Chain: A: PDB Molecule:thio-disulfide isomerase/thioredoxin; PDBTitle: crystal structure of thio-disulfide isomerase from thermus2 thermophilus 93 d2qf3a1 not modelled 31.0 27 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Prokaryotic proteases 94 d2a29a1 not modelled 30.3 17 Fold:Metal cation-transporting ATPase, ATP-binding domain N Superfamily:Metal cation-transporting ATPase, ATP-binding domain N Family:Metal cation-transporting ATPase, ATP-binding domain N 95 c3k6zA_ not modelled 30.3 14 PDB header:hydrolase Chain: A: PDB Molecule:possible membrane-associated serine protease; PDBTitle: crystal structure of rv3671c protease, inactive form 96 c2rceI_ not modelled 30.2 29 PDB header:hydrolase Chain: I: PDB Molecule:protease degs; PDBTitle: dfp modified degs delta pdz 97 c3lwaA_ not modelled 29.9 11 PDB header:isomerase Chain: A: PDB Molecule:secreted thiol-disulfide isomerase; PDBTitle: the crystal structure of a secreted thiol-disulfide2 isomerase from corynebacterium glutamicum to 1.75a 98 d1nq4a_ not modelled 28.8 16 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 99 d1l1ja_ not modelled 28.5 36 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Prokaryotic proteases 100 d1y0na_ not modelled 27.2 13 Fold:YehU-like Superfamily:YehU-like Family:YehU-like 101 c3ce7A_ not modelled 25.9 22 PDB header:biosynthetic protein Chain: A: PDB Molecule:specific mitochodrial acyl carrier protein; PDBTitle: crystal structure of toxoplasma specific mitochodrial acyl2 carrier protein, 59.m03510 102 d1or5a_ not modelled 25.3 13 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 103 c1pbwB_ not modelled 24.6 6 PDB header:phosphotransferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase; PDBTitle: structure of bcr-homology (bh) domain 104 c3stiC_ not modelled 24.5 29 PDB header:hydrolase Chain: C: PDB Molecule:protease degq; PDBTitle: crystal structure of the protease domain of degq from escherichia coli 105 d1yj5a1 not modelled 24.4 10 Fold:HAD-like Superfamily:HAD-like Family:phosphatase domain of polynucleotide kinase 106 d1ky9a2 not modelled 24.2 29 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Prokaryotic proteases 107 d1x6va1 not modelled 23.8 20 Fold:PUA domain-like Superfamily:PUA domain-like Family:ATP sulfurylase N-terminal domain 108 d1h2sa_ not modelled 23.2 7 Fold:Family A G protein-coupled receptor-like Superfamily:Family A G protein-coupled receptor-like Family:Bacteriorhodopsin-like 109 d1p0za_ not modelled 23.0 27 Fold:Profilin-like Superfamily:Sensory domain-like Family:Sensory domain of two-component sensor kinase 110 d1uaza_ not modelled 22.9 11 Fold:Family A G protein-coupled receptor-like Superfamily:Family A G protein-coupled receptor-like Family:Bacteriorhodopsin-like 111 c1r6xA_ not modelled 21.9 16 PDB header:transferase Chain: A: PDB Molecule:atp:sulfate adenylyltransferase; PDBTitle: the crystal structure of a truncated form of yeast atp2 sulfurylase, lacking the c-terminal aps kinase-like domain,3 in complex with sulfate

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0