Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	L	N	L	Q	D	K	Q	A	I	V	A	E	V	S	E	V	A	K	G	A	L	S	A	V	V	A	D	S	R	G	V	T	V	D	K	M	T	E	L	R	K	A	G	R	E	A	G	V	Y	M	R	V	V	R	N	T	L	L
Secondary structure
SS confidence
Disorder		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	R	A	V	E	G	T	P	F	E	C	L	K	D	A	F	V	G	P	T	L	I	A	Y	S	M	E	H	P	G	A	A	A	R	L	F	K	E	F	A	K	A	N	A	K	F	E	V	K	A	A	A	F	E	G	E	L	I	P	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.
Sequence		S	Q	I	D	R	L	A	T	L	P	T	Y	E	E	A	I	A	R	L	M	A	T	M	K	E	A	S	A	G	K	L	V	R	T	L	A	A	V	R	D	A	K	E	A	A
Secondary structure
SS confidence
Disorder																									?	?	?	?																?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1zav chain A domain 1 Region: 3 - 162 Aligned: 160 Modelled: 160 Confidence: 100.0% Identity: 36% Fold: Ferredoxin-like Superfamily: Ribosomal protein L10-like Family: Ribosomal protein L10-like Phyre2 PDB 3a1y chain G Region: 1 - 123 Aligned: 123 Modelled: 123 Confidence: 99.9% Identity: 21% PDB header:ribosomal protein Chain: G: PDB Molecule:acidic ribosomal protein p0; PDBTitle: the structure of protein complex Phyre2 PDB 3jyw chain 8 Region: 5 - 104 Aligned: 99 Modelled: 100 Confidence: 99.9% Identity: 23% PDB header:ribosome Chain: 8: PDB Molecule:60s ribosomal protein lp0; PDBTitle: structure of the 60s proteins for eukaryotic ribosome based on cryo-em2 map of thermomyces lanuginosus ribosome at 8.9a resolution Phyre2 PDB 3jsy chain A Region: 6 - 99 Aligned: 93 Modelled: 94 Confidence: 99.9% Identity: 23% PDB header:ribosomal protein Chain: A: PDB Molecule:acidic ribosomal protein p0 homolog; PDBTitle: n-terminal fragment of ribosomal protein l10 from methanococcus2 jannaschii Phyre2 PDB 3izc chain S Region: 1 - 99 Aligned: 98 Modelled: 99 Confidence: 99.9% Identity: 24% PDB header:ribosome Chain: S: PDB Molecule:60s ribosomal protein rpl20 (l18ae); PDBTitle: localization of the large subunit ribosomal proteins into a 6.1 a2 cryo-em map of saccharomyces cerevisiae translating 80s ribosome Phyre2 PDB 3iz5 chain S Region: 1 - 99 Aligned: 98 Modelled: 99 Confidence: 99.9% Identity: 19% PDB header:ribosome Chain: S: PDB Molecule:60s ribosomal protein l18a (l18ae); PDBTitle: localization of the large subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome Phyre2 PDB 1kee chain H Region: 25 - 115 Aligned: 75 Modelled: 91 Confidence: 50.9% Identity: 20% PDB header:ligase Chain: H: PDB Molecule:carbamoyl-phosphate synthetase small chain; PDBTitle: inactivation of the amidotransferase activity of carbamoyl phosphate2 synthetase by the antibiotic acivicin Phyre2 PDB 1a9x chain B domain 2 Region: 25 - 115 Aligned: 75 Modelled: 91 Confidence: 40.0% Identity: 19% Fold: Flavodoxin-like Superfamily: Class I glutamine amidotransferase-like Family: Class I glutamine amidotransferases (GAT) Phyre2 PDB 1th8 chain B Region: 9 - 77 Aligned: 69 Modelled: 69 Confidence: 26.1% Identity: 13% Fold: SpoIIaa-like Superfamily: SpoIIaa-like Family: Anti-sigma factor antagonist SpoIIaa Phyre2 PDB 1ln4 chain A Region: 1 - 84 Aligned: 80 Modelled: 84 Confidence: 24.5% Identity: 20% Fold: IF3-like Superfamily: YhbY-like Family: YhbY-like Phyre2 PDB 1vc1 chain A Region: 9 - 76 Aligned: 68 Modelled: 68 Confidence: 19.1% Identity: 10% Fold: SpoIIaa-like Superfamily: SpoIIaa-like Family: Anti-sigma factor antagonist SpoIIaa Phyre2 PDB 1luz chain A Region: 25 - 56 Aligned: 32 Modelled: 32 Confidence: 18.3% Identity: 28% Fold: OB-fold Superfamily: Nucleic acid-binding proteins Family: Cold shock DNA-binding domain-like Phyre2 PDB 1auz chain A Region: 9 - 77 Aligned: 69 Modelled: 69 Confidence: 17.3% Identity: 10% Fold: SpoIIaa-like Superfamily: SpoIIaa-like Family: Anti-sigma factor antagonist SpoIIaa Phyre2 PDB 3oir chain A Region: 9 - 98 Aligned: 86 Modelled: 90 Confidence: 14.7% Identity: 17% PDB header:transport protein Chain: A: PDB Molecule:sulfate transporter sulfate transporter family protein; PDBTitle: crystal structure of sulfate transporter family protein from wolinella2 succinogenes Phyre2 PDB 1h1j chain S Region: 29 - 62 Aligned: 31 Modelled: 34 Confidence: 14.1% Identity: 23% Fold: LEM/SAP HeH motif Superfamily: SAP domain Family: SAP domain Phyre2 PDB 1hl2 chain A Region: 1 - 131 Aligned: 109 Modelled: 115 Confidence: 13.8% Identity: 22% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 2qv6 chain D Region: 56 - 112 Aligned: 54 Modelled: 57 Confidence: 13.4% Identity: 17% PDB header:hydrolase Chain: D: PDB Molecule:gtp cyclohydrolase iii; PDBTitle: gtp cyclohydrolase iii from m. jannaschii (mj0145)2 complexed with gtp and metal ions Phyre2 PDB 2fkn chain C Region: 31 - 95 Aligned: 64 Modelled: 65 Confidence: 12.2% Identity: 27% PDB header:lyase Chain: C: PDB Molecule:urocanate hydratase; PDBTitle: crystal structure of urocanase from bacillus subtilis Phyre2 PDB 1x87 chain A Region: 31 - 95 Aligned: 64 Modelled: 64 Confidence: 11.6% Identity: 30% Fold: Urocanase Superfamily: Urocanase Family: Urocanase Phyre2 PDB 3brc chain A Region: 7 - 52 Aligned: 46 Modelled: 46 Confidence: 11.4% Identity: 15% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved protein of unknown function; PDBTitle: crystal structure of a conserved protein of unknown function from2 methanobacterium thermoautotrophicum Phyre2 1 d1zava1 2 c3a1yG_ 3 c3jyw8_ 4 c3jsyA_ 5 c3izcs_ 6 c3iz5s_ 7 c1keeH_ 8 d1a9xb2 9 d1th8b_ 10 d1ln4a_ 11 d1vc1a_ 12 d1luza_ 13 d1auza_ 14 c3oirA_ 15 d1h1js_ 16 d1hl2a_ 17 c2qv6D_ 18 c2fknC_ 19 d1x87a_ 20 c3brcA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1zava1 100.0 36 Fold:Ferredoxin-like Superfamily:Ribosomal protein L10-like Family:Ribosomal protein L10-like 2 c3a1yG_ 99.9 21 PDB header:ribosomal protein Chain: G: PDB Molecule:acidic ribosomal protein p0; PDBTitle: the structure of protein complex 3 c3jyw8_ 99.9 23 PDB header:ribosome Chain: 8: PDB Molecule:60s ribosomal protein lp0; PDBTitle: structure of the 60s proteins for eukaryotic ribosome based on cryo-em2 map of thermomyces lanuginosus ribosome at 8.9a resolution 4 c3jsyA_ 99.9 23 PDB header:ribosomal protein Chain: A: PDB Molecule:acidic ribosomal protein p0 homolog; PDBTitle: n-terminal fragment of ribosomal protein l10 from methanococcus2 jannaschii 5 c3izcs_ 99.9 24 PDB header:ribosome Chain: S: PDB Molecule:60s ribosomal protein rpl20 (l18ae); PDBTitle: localization of the large subunit ribosomal proteins into a 6.1 a2 cryo-em map of saccharomyces cerevisiae translating 80s ribosome 6 c3iz5s_ 99.9 19 PDB header:ribosome Chain: S: PDB Molecule:60s ribosomal protein l18a (l18ae); PDBTitle: localization of the large subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome 7 c1keeH_ 50.9 20 PDB header:ligase Chain: H: PDB Molecule:carbamoyl-phosphate synthetase small chain; PDBTitle: inactivation of the amidotransferase activity of carbamoyl phosphate2 synthetase by the antibiotic acivicin 8 d1a9xb2 40.0 19 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 9 d1th8b_ 26.1 13 Fold:SpoIIaa-like Superfamily:SpoIIaa-like Family:Anti-sigma factor antagonist SpoIIaa 10 d1ln4a_ 24.5 20 Fold:IF3-like Superfamily:YhbY-like Family:YhbY-like 11 d1vc1a_ 19.1 10 Fold:SpoIIaa-like Superfamily:SpoIIaa-like Family:Anti-sigma factor antagonist SpoIIaa 12 d1luza_ 18.3 28 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 13 d1auza_ 17.3 10 Fold:SpoIIaa-like Superfamily:SpoIIaa-like Family:Anti-sigma factor antagonist SpoIIaa 14 c3oirA_ 14.7 17 PDB header:transport protein Chain: A: PDB Molecule:sulfate transporter sulfate transporter family protein; PDBTitle: crystal structure of sulfate transporter family protein from wolinella2 succinogenes 15 d1h1js_ 14.1 23 Fold:LEM/SAP HeH motif Superfamily:SAP domain Family:SAP domain 16 d1hl2a_ 13.8 22 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 17 c2qv6D_ 13.4 17 PDB header:hydrolase Chain: D: PDB Molecule:gtp cyclohydrolase iii; PDBTitle: gtp cyclohydrolase iii from m. jannaschii (mj0145)2 complexed with gtp and metal ions 18 c2fknC_ 12.2 27 PDB header:lyase Chain: C: PDB Molecule:urocanate hydratase; PDBTitle: crystal structure of urocanase from bacillus subtilis 19 d1x87a_ 11.6 30 Fold:Urocanase Superfamily:Urocanase Family:Urocanase 20 c3brcA_ 11.4 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved protein of unknown function; PDBTitle: crystal structure of a conserved protein of unknown function from2 methanobacterium thermoautotrophicum 21 c3d5bJ_ not modelled 11.3 38 PDB header:ribosome Chain: J: PDB Molecule:50s ribosomal protein l10; PDBTitle: structural basis for translation termination on the 70s ribosome. this2 file contains the 50s subunit of one 70s ribosome. the entire crystal3 structure contains two 70s ribosomes as described in remark 400. 22 d3ceda1 not modelled 11.2 18 Fold:Ferredoxin-like Superfamily:ACT-like Family:NIL domain-like 23 c2y0dB_ not modelled 10.7 12 PDB header:oxidoreductase Chain: B: PDB Molecule:udp-glucose dehydrogenase; PDBTitle: bcec mutation y10k 24 d1zrja1 not modelled 10.6 31 Fold:LEM/SAP HeH motif Superfamily:SAP domain Family:SAP domain 25 c3rhtB_ not modelled 9.2 16 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:(gatase1)-like protein; PDBTitle: crystal structure of type 1 glutamine amidotransferase (gatase1)-like2 protein from planctomyces limnophilus 26 c2a1sC_ not modelled 8.8 12 PDB header:hydrolase Chain: C: PDB Molecule:poly(a)-specific ribonuclease parn; PDBTitle: crystal structure of native parn nuclease domain 27 d1jo0a_ not modelled 8.5 18 Fold:IF3-like Superfamily:YhbY-like Family:YhbY-like 28 c3m20A_ not modelled 8.4 25 PDB header:isomerase Chain: A: PDB Molecule:4-oxalocrotonate tautomerase, putative; PDBTitle: crystal structure of dmpi from archaeoglobus fulgidus determined to2 2.37 angstroms resolution 29 c3f43A_ not modelled 8.3 11 PDB header:transcription Chain: A: PDB Molecule:putative anti-sigma factor antagonist tm1081; PDBTitle: crystal structure of a putative anti-sigma factor antagonist (tm1081)2 from thermotoga maritima at 1.59 a resolution 30 d2ohwa1 not modelled 8.0 13 Fold:Bacillus chorismate mutase-like Superfamily:YueI-like Family:YueI-like 31 d1jjga_ not modelled 8.0 22 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 32 c2klnA_ not modelled 7.9 15 PDB header:transport protein Chain: A: PDB Molecule:probable sulphate-transport transmembrane protein, cog0659; PDBTitle: solution structure of stas domain of rv1739c from m. tuberculosis 33 c2qexG_ not modelled 6.7 64 PDB header:ribosome Chain: G: PDB Molecule:acidic ribosomal protein p0 homolog; PDBTitle: negamycin binds to the wall of the nascent chain exit tunnel of the2 50s ribosomal subunit 34 c2zpmA_ not modelled 6.6 13 PDB header:hydrolase Chain: A: PDB Molecule:regulator of sigma e protease; PDBTitle: crystal structure analysis of pdz domain b 35 c1ykaA_ not modelled 6.6 10 PDB header:electron transport Chain: A: PDB Molecule:monothiol glutaredoxin ydhd; PDBTitle: solution structure of grx4, a monothiol glutaredoxin from2 e. coli. 36 c3cxjB_ not modelled 6.3 16 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an uncharacterized protein from2 methanothermobacter thermautotrophicus 37 d1h4xa_ not modelled 6.3 7 Fold:SpoIIaa-like Superfamily:SpoIIaa-like Family:Anti-sigma factor antagonist SpoIIaa 38 c3lerA_ not modelled 6.3 18 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 campylobacter jejuni subsp. jejuni nctc 11168 39 d1iioa_ not modelled 6.2 11 Fold:EF Hand-like Superfamily:Hypothetical protein MTH865 Family:Hypothetical protein MTH865 40 d1l1sa_ not modelled 6.1 27 Fold:DsrEFH-like Superfamily:DsrEFH-like Family:DsrEF-like 41 d1uwka_ not modelled 6.1 27 Fold:Urocanase Superfamily:Urocanase Family:Urocanase 42 c2y9jt_ not modelled 6.0 7 PDB header:protein transport Chain: T: PDB Molecule:protein prgh; PDBTitle: three-dimensional model of salmonella's needle complex at2 subnanometer resolution 43 d1gyxa_ not modelled 6.0 32 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:4-oxalocrotonate tautomerase-like 44 c1q14A_ not modelled 6.0 11 PDB header:hydrolase Chain: A: PDB Molecule:hst2 protein; PDBTitle: structure and autoregulation of the yeast hst2 homolog of sir2 45 d1wdea_ not modelled 5.9 18 Fold:Tetrapyrrole methylase Superfamily:Tetrapyrrole methylase Family:Tetrapyrrole methylase 46 d1yc5a1 not modelled 5.8 12 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 47 c3mglA_ not modelled 5.7 9 PDB header:transport protein Chain: A: PDB Molecule:sulfate permease family protein; PDBTitle: crystal structure of permease family protein from vibrio2 cholerae 48 d1phza1 not modelled 5.5 20 Fold:Ferredoxin-like Superfamily:ACT-like Family:Phenylalanine metabolism regulatory domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0