Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	T	R	L	N	L	L	C	E	A	G	V	I	D	K	D	I	C	K	G	M	M	Q	V	V	N	V	L	E	T	E	C	H	L	P	V	R	S	E	Q	G	T	M	A	M	T	H	M	A	S	A	L	M	R	S	R	R	G	E
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	I	E	P	L	D	N	E	L	L	A	E	L	A	Q	S	S	H	W	Q	A	V	V	Q	L	H	Q	V	L	L	K	E	F	A	L	E	V	N	P	C	E	E	G	Y	L	L	A	N	L	Y	G	L	W	M	A	A	N	E	E	V
Secondary structure
SS confidence
Disorder		?	?	?	?																																																			?	?	?	?	?	?
Disorder confidence
Sequence
Secondary structure
SS confidence
Disorder
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1h99 chain A domain 1 Region: 12 - 117 Aligned: 105 Modelled: 106 Confidence: 99.9% Identity: 8% Fold: PTS-regulatory domain, PRD Superfamily: PTS-regulatory domain, PRD Family: PTS-regulatory domain, PRD Phyre2 PDB 1h99 chain A domain 2 Region: 17 - 113 Aligned: 96 Modelled: 97 Confidence: 99.8% Identity: 14% Fold: PTS-regulatory domain, PRD Superfamily: PTS-regulatory domain, PRD Family: PTS-regulatory domain, PRD Phyre2 PDB 3gwh chain B Region: 20 - 112 Aligned: 92 Modelled: 93 Confidence: 99.8% Identity: 21% PDB header:transcription Chain: B: PDB Molecule:transcriptional antiterminator (bglg family); PDBTitle: crystallographic ab initio protein solution far below atomic2 resolution Phyre2 PDB 1h99 chain A Region: 14 - 119 Aligned: 105 Modelled: 106 Confidence: 99.7% Identity: 8% PDB header:transcriptional antiterminator Chain: A: PDB Molecule:transcription antiterminator lict; PDBTitle: prd of lict antiterminator from bacillus subtilis Phyre2 PDB 3sqn chain B Region: 15 - 119 Aligned: 104 Modelled: 105 Confidence: 98.7% Identity: 7% PDB header:transcription regulator Chain: B: PDB Molecule:conserved domain protein; PDBTitle: putative mga family transcriptional regulator from enterococcus2 faecalis Phyre2 PDB 3nuf chain B Region: 15 - 115 Aligned: 95 Modelled: 101 Confidence: 98.1% Identity: 18% PDB header:transcription regulator Chain: B: PDB Molecule:prd-containing transcription regulator; PDBTitle: crystal structure of a prd-containing transcription regulator2 (lsei_2718) from lactobacillus casei atcc 334 at 1.38 a resolution Phyre2 PDB 2kci chain A Region: 81 - 102 Aligned: 22 Modelled: 22 Confidence: 57.3% Identity: 14% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative acyl carrier protein; PDBTitle: solution nmr structure of gmet_2339 from geobacter2 metallireducens. northeast structural genomics consortium3 target gmr141 Phyre2 PDB 2jq4 chain A Region: 81 - 102 Aligned: 22 Modelled: 22 Confidence: 56.3% Identity: 27% PDB header:structural genomics Chain: A: PDB Molecule:hypothetical protein atu2571; PDBTitle: complete resonance assignments and solution structure2 calculation of atc2521 (nesg id: att6) from agrobacterium3 tumefaciens Phyre2 PDB 2jq4 chain A domain 1 Region: 81 - 102 Aligned: 22 Modelled: 22 Confidence: 56.3% Identity: 27% Fold: Acyl carrier protein-like Superfamily: ACP-like Family: Acyl-carrier protein (ACP) Phyre2 PDB 3lmo chain A Region: 81 - 103 Aligned: 23 Modelled: 23 Confidence: 55.9% Identity: 9% PDB header:transferase Chain: A: PDB Molecule:specialized acyl carrier protein; PDBTitle: crystal structure of specialized acyl carrier protein2 (rpa2022) from rhodopseudomonas palustris, northeast3 structural genomics consortium target rpr324 Phyre2 PDB 3id6 chain A Region: 15 - 99 Aligned: 85 Modelled: 85 Confidence: 42.4% Identity: 5% PDB header:transferase Chain: A: PDB Molecule:pre mrna splicing protein; PDBTitle: crystal structure of sulfolobus solfataricus nop5 (1-262) and2 fibrillarin complex Phyre2 PDB 2l4b chain A Region: 81 - 103 Aligned: 23 Modelled: 23 Confidence: 40.0% Identity: 26% PDB header:transferase Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: solution structure of a putative acyl carrier protein from anaplasma2 phagocytophilum. seattle structural genomics center for infectious3 disease target anpha.01018.a Phyre2 PDB 1x3o chain A Region: 81 - 103 Aligned: 23 Modelled: 23 Confidence: 38.8% Identity: 35% PDB header:lipid transport Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: crystal structure of the acyl carrier protein from thermus2 thermophilus hb8 Phyre2 PDB 2qnw chain A Region: 81 - 102 Aligned: 22 Modelled: 22 Confidence: 38.7% Identity: 18% PDB header:signaling protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: toxoplasma gondii apicoplast-targeted acyl carrier protein Phyre2 PDB 1f80 chain D Region: 81 - 103 Aligned: 23 Modelled: 23 Confidence: 37.6% Identity: 30% Fold: Acyl carrier protein-like Superfamily: ACP-like Family: Acyl-carrier protein (ACP) Phyre2 PDB 3ce7 chain A Region: 82 - 102 Aligned: 21 Modelled: 21 Confidence: 37.3% Identity: 14% PDB header:biosynthetic protein Chain: A: PDB Molecule:specific mitochodrial acyl carrier protein; PDBTitle: crystal structure of toxoplasma specific mitochodrial acyl2 carrier protein, 59.m03510 Phyre2 PDB 2eht chain A Region: 81 - 102 Aligned: 22 Modelled: 22 Confidence: 36.3% Identity: 27% PDB header:lipid transport Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: crystal structure of acyl carrier protein from aquifex aeolicus (form2 2) Phyre2 PDB 2fvf chain A Region: 81 - 102 Aligned: 22 Modelled: 22 Confidence: 32.8% Identity: 23% PDB header:biosynthetic protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: structure of 10:0-acp (protein with docked fatty acid) Phyre2 PDB 3ejb chain C Region: 81 - 103 Aligned: 23 Modelled: 23 Confidence: 32.3% Identity: 30% PDB header:oxidoreductase/lipid transport Chain: C: PDB Molecule:acyl carrier protein; PDBTitle: crystal structure of p450bioi in complex with tetradecanoic2 acid ligated acyl carrier protein Phyre2 PDB 2dnw chain A Region: 81 - 102 Aligned: 22 Modelled: 22 Confidence: 31.9% Identity: 18% PDB header:transport protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: solution structure of rsgi ruh-059, an acp domain of acyl2 carrier protein, mitochondrial [precursor] from human cdna Phyre2 1 d1h99a1 2 d1h99a2 3 c3gwhB_ 4 c1h99A_ 5 c3sqnB_ 6 c3nufB_ 7 c2kciA_ 8 c2jq4A_ 9 d2jq4a1 10 c3lmoA_ 11 c3id6A_ 12 c2l4bA_ 13 c1x3oA_ 14 c2qnwA_ 15 d1f80d_ 16 c3ce7A_ 17 c2ehtA_ 18 c2fvfA_ 19 c3ejbC_ 20 c2dnwA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1h99a1 99.9 8 Fold:PTS-regulatory domain, PRD Superfamily:PTS-regulatory domain, PRD Family:PTS-regulatory domain, PRD 2 d1h99a2 99.8 14 Fold:PTS-regulatory domain, PRD Superfamily:PTS-regulatory domain, PRD Family:PTS-regulatory domain, PRD 3 c3gwhB_ 99.8 21 PDB header:transcription Chain: B: PDB Molecule:transcriptional antiterminator (bglg family); PDBTitle: crystallographic ab initio protein solution far below atomic2 resolution 4 c1h99A_ 99.7 8 PDB header:transcriptional antiterminator Chain: A: PDB Molecule:transcription antiterminator lict; PDBTitle: prd of lict antiterminator from bacillus subtilis 5 c3sqnB_ 98.7 7 PDB header:transcription regulator Chain: B: PDB Molecule:conserved domain protein; PDBTitle: putative mga family transcriptional regulator from enterococcus2 faecalis 6 c3nufB_ 98.1 18 PDB header:transcription regulator Chain: B: PDB Molecule:prd-containing transcription regulator; PDBTitle: crystal structure of a prd-containing transcription regulator2 (lsei_2718) from lactobacillus casei atcc 334 at 1.38 a resolution 7 c2kciA_ 57.3 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative acyl carrier protein; PDBTitle: solution nmr structure of gmet_2339 from geobacter2 metallireducens. northeast structural genomics consortium3 target gmr141 8 c2jq4A_ 56.3 27 PDB header:structural genomics Chain: A: PDB Molecule:hypothetical protein atu2571; PDBTitle: complete resonance assignments and solution structure2 calculation of atc2521 (nesg id: att6) from agrobacterium3 tumefaciens 9 d2jq4a1 56.3 27 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 10 c3lmoA_ 55.9 9 PDB header:transferase Chain: A: PDB Molecule:specialized acyl carrier protein; PDBTitle: crystal structure of specialized acyl carrier protein2 (rpa2022) from rhodopseudomonas palustris, northeast3 structural genomics consortium target rpr324 11 c3id6A_ 42.4 5 PDB header:transferase Chain: A: PDB Molecule:pre mrna splicing protein; PDBTitle: crystal structure of sulfolobus solfataricus nop5 (1-262) and2 fibrillarin complex 12 c2l4bA_ 40.0 26 PDB header:transferase Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: solution structure of a putative acyl carrier protein from anaplasma2 phagocytophilum. seattle structural genomics center for infectious3 disease target anpha.01018.a 13 c1x3oA_ 38.8 35 PDB header:lipid transport Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: crystal structure of the acyl carrier protein from thermus2 thermophilus hb8 14 c2qnwA_ 38.7 18 PDB header:signaling protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: toxoplasma gondii apicoplast-targeted acyl carrier protein 15 d1f80d_ 37.6 30 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 16 c3ce7A_ 37.3 14 PDB header:biosynthetic protein Chain: A: PDB Molecule:specific mitochodrial acyl carrier protein; PDBTitle: crystal structure of toxoplasma specific mitochodrial acyl2 carrier protein, 59.m03510 17 c2ehtA_ 36.3 27 PDB header:lipid transport Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: crystal structure of acyl carrier protein from aquifex aeolicus (form2 2) 18 c2fvfA_ 32.8 23 PDB header:biosynthetic protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: structure of 10:0-acp (protein with docked fatty acid) 19 c3ejbC_ 32.3 30 PDB header:oxidoreductase/lipid transport Chain: C: PDB Molecule:acyl carrier protein; PDBTitle: crystal structure of p450bioi in complex with tetradecanoic2 acid ligated acyl carrier protein 20 c2dnwA_ 31.9 18 PDB header:transport protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: solution structure of rsgi ruh-059, an acp domain of acyl2 carrier protein, mitochondrial [precursor] from human cdna 21 c2fq2A_ not modelled 30.1 18 PDB header:lipid transport Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: solution structure of minor conformation of holo-acyl2 carrier protein from malaria parasite plasmodium falciparum 22 c2lkiA_ not modelled 29.5 32 PDB header:lipid transport Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: solution nmr structure of holo acyl carrier protein ne2163 from2 nitrosomonas europaea. northeast structural genomics consortium3 target net1. 23 c2cgqA_ not modelled 28.1 22 PDB header:protein transport Chain: A: PDB Molecule:acyl carrier protein acpa; PDBTitle: a putative acyl carrier protein(rv0033) from mycobacterium2 tuberculosis 24 c3id5E_ not modelled 27.7 5 PDB header:transferase/ribosomal protein/rna Chain: E: PDB Molecule:pre mrna splicing protein; PDBTitle: crystal structure of sulfolobus solfataricus c/d rnp assembled with2 nop5, fibrillarin, l7ae and a split half c/d rna 25 c2cnrA_ not modelled 26.7 9 PDB header:lipid transport Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: structural studies on the interaction of scfas acp with2 acps 26 c2amwA_ not modelled 25.6 32 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ne2163; PDBTitle: solution nmr structure of protein ne2163 from nitrosomonas europaea.2 northeast structural genomics consortium target net1. 27 c2kwlA_ not modelled 25.4 18 PDB header:lipid binding protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: solution structure of acyl carrier protein from borrelia burgdorferi 28 d1t8ka_ not modelled 21.6 32 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 29 d1klpa_ not modelled 20.8 5 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 30 d2pnga1 not modelled 20.3 27 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 31 d1nq4a_ not modelled 20.1 4 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 32 d1or5a_ not modelled 19.5 17 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 33 d1dv5a_ not modelled 19.4 18 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:apo-D-alanyl carrier protein 34 d1vkua_ not modelled 18.8 32 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 35 d1vlpa1 not modelled 17.7 21 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like 36 d1ybea2 not modelled 16.1 16 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like 37 d2af8a_ not modelled 14.2 10 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP) 38 c2l3vA_ not modelled 14.1 21 PDB header:lipid binding protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: nmr structure of acyl carrier protein from brucella melitensis 39 c1zxjB_ not modelled 12.7 22 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein mg377 homolog; PDBTitle: crystal structure of the hypthetical mycoplasma protein,2 mpn555 40 d1d0qa_ not modelled 11.9 16 Fold:Rubredoxin-like Superfamily:Zinc beta-ribbon Family:DNA primase zinc finger 41 c2kr5A_ not modelled 11.2 8 PDB header:transport protein Chain: A: PDB Molecule:aflatoxin biosynthesis polyketide synthase; PDBTitle: solution structure of an acyl carrier protein domain from fungal type2 i polyketide synthase 42 d1t3ta1 not modelled 10.2 18 Fold:RuvA C-terminal domain-like Superfamily:FGAM synthase PurL, linker domain Family:FGAM synthase PurL, linker domain 43 d2prva1 not modelled 9.0 7 Fold:SMI1/KNR4-like Superfamily:SMI1/KNR4-like Family:SMI1/KNR4-like 44 c3d9wA_ not modelled 8.6 22 PDB header:transferase Chain: A: PDB Molecule:putative acetyltransferase; PDBTitle: crystal structure analysis of nocardia farcinica arylamine2 n-acetyltransferase 45 c3d5pB_ not modelled 7.6 14 PDB header:gene regulation Chain: B: PDB Molecule:putative glucan synthesis regulator of smi1/knr4 family; PDBTitle: crystal structure of a putative glucan synthesis regulator of2 smi1/knr4 family (bf1740) from bacteroides fragilis nctc 9343 at 1.453 a resolution 46 d1e2ta_ not modelled 7.2 35 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:Arylamine N-acetyltransferase 47 d1w5ra1 not modelled 6.1 10 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:Arylamine N-acetyltransferase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0