Phyre 2 Results for P45551

Phyre Home | Retrieve Phyre Job Id

Email | l.a.kelley@imperial.ac.uk
Description | P45551
Date | Thu Jan 5 12:03:10 GMT 2012
Unique Job ID | b97bb67ef300a792

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template d1h99a1
Top template information
Fold:PTS-regulatory domain, PRD Superfamily:PTS-regulatory domain, PRD Family:PTS-regulatory domain, PRD
Confidence and coverage
Confidence: | 99.9% | Coverage: | 88%
105 residues ( 88% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

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Sequence |  | M | E | T | R | L | N | L | L | C | E | A | G | V | I | D | K | D | I | C | K | G | M | M | Q | V | V | N | V | L | E | T | E | C | H | L | P | V | R | S | E | Q | G | T | M | A | M | T | H | M | A | S | A | L | M | R | S | R | R | G | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | E | I | E | P | L | D | N | E | L | L | A | E | L | A | Q | S | S | H | W | Q | A | V | V | Q | L | H | Q | V | L | L | K | E | F | A | L | E | V | N | P | C | E | E | G | Y | L | L | A | N | L | Y | G | L | W | M | A | A | N | E | E | V
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Sequence |
Secondary structure |
SS confidence |
Disorder |
Disorder confidence |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| d1h99a1 |

### PDB 1h99 chain A domain 1

Region: 12 - 117
Aligned: 105
Modelled: 106
Confidence: 99.9%
Identity: 8%
Fold: PTS-regulatory domain, PRD
Superfamily: PTS-regulatory domain, PRD
Family: PTS-regulatory domain, PRD

Phyre2
2 |
| d1h99a2 |

### PDB 1h99 chain A domain 2

Region: 17 - 113
Aligned: 96
Modelled: 97
Confidence: 99.8%
Identity: 14%
Fold: PTS-regulatory domain, PRD
Superfamily: PTS-regulatory domain, PRD
Family: PTS-regulatory domain, PRD

Phyre2
3 |
| c3gwhB_ |

### PDB 3gwh chain B

Region: 20 - 112
Aligned: 92
Modelled: 93
Confidence: 99.8%
Identity: 21%
PDB header:transcription
Chain: B: PDB Molecule:transcriptional antiterminator (bglg family);
PDBTitle: crystallographic ab initio protein solution far below atomic2 resolution

Phyre2
4 |
| c1h99A_ |

### PDB 1h99 chain A

Region: 14 - 119
Aligned: 105
Modelled: 106
Confidence: 99.7%
Identity: 8%
PDB header:transcriptional antiterminator
Chain: A: PDB Molecule:transcription antiterminator lict;
PDBTitle: prd of lict antiterminator from bacillus subtilis

Phyre2
5 |
| c3sqnB_ |

### PDB 3sqn chain B

Region: 15 - 119
Aligned: 104
Modelled: 105
Confidence: 98.7%
Identity: 7%
PDB header:transcription regulator
Chain: B: PDB Molecule:conserved domain protein;
PDBTitle: putative mga family transcriptional regulator from enterococcus2 faecalis

Phyre2
6 |
| c3nufB_ |

### PDB 3nuf chain B

Region: 15 - 115
Aligned: 95
Modelled: 101
Confidence: 98.1%
Identity: 18%
PDB header:transcription regulator
Chain: B: PDB Molecule:prd-containing transcription regulator;
PDBTitle: crystal structure of a prd-containing transcription regulator2 (lsei_2718) from lactobacillus casei atcc 334 at 1.38 a resolution

Phyre2
7 |
| c2kciA_ |

### PDB 2kci chain A

Region: 81 - 102
Aligned: 22
Modelled: 22
Confidence: 57.3%
Identity: 14%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative acyl carrier protein;
PDBTitle: solution nmr structure of gmet_2339 from geobacter2 metallireducens. northeast structural genomics consortium3 target gmr141

Phyre2
8 |
| c2jq4A_ |

### PDB 2jq4 chain A

Region: 81 - 102
Aligned: 22
Modelled: 22
Confidence: 56.3%
Identity: 27%
PDB header:structural genomics
Chain: A: PDB Molecule:hypothetical protein atu2571;
PDBTitle: complete resonance assignments and solution structure2 calculation of atc2521 (nesg id: att6) from agrobacterium3 tumefaciens

Phyre2
9 |
| d2jq4a1 |

### PDB 2jq4 chain A domain 1

Region: 81 - 102
Aligned: 22
Modelled: 22
Confidence: 56.3%
Identity: 27%
Fold: Acyl carrier protein-like
Superfamily: ACP-like
Family: Acyl-carrier protein (ACP)

Phyre2
10 |
| c3lmoA_ |

### PDB 3lmo chain A

Region: 81 - 103
Aligned: 23
Modelled: 23
Confidence: 55.9%
Identity: 9%
PDB header:transferase
Chain: A: PDB Molecule:specialized acyl carrier protein;
PDBTitle: crystal structure of specialized acyl carrier protein2 (rpa2022) from rhodopseudomonas palustris, northeast3 structural genomics consortium target rpr324

Phyre2
11 |
| c3id6A_ |

### PDB 3id6 chain A

Region: 15 - 99
Aligned: 85
Modelled: 85
Confidence: 42.4%
Identity: 5%
PDB header:transferase
Chain: A: PDB Molecule:pre mrna splicing protein;
PDBTitle: crystal structure of sulfolobus solfataricus nop5 (1-262) and2 fibrillarin complex

Phyre2
12 |
| c2l4bA_ |

### PDB 2l4b chain A

Region: 81 - 103
Aligned: 23
Modelled: 23
Confidence: 40.0%
Identity: 26%
PDB header:transferase
Chain: A: PDB Molecule:acyl carrier protein;
PDBTitle: solution structure of a putative acyl carrier protein from anaplasma2 phagocytophilum. seattle structural genomics center for infectious3 disease target anpha.01018.a

Phyre2
13 |
| c1x3oA_ |

### PDB 1x3o chain A

Region: 81 - 103
Aligned: 23
Modelled: 23
Confidence: 38.8%
Identity: 35%
PDB header:lipid transport
Chain: A: PDB Molecule:acyl carrier protein;
PDBTitle: crystal structure of the acyl carrier protein from thermus2 thermophilus hb8

Phyre2
14 |
| c2qnwA_ |

### PDB 2qnw chain A

Region: 81 - 102
Aligned: 22
Modelled: 22
Confidence: 38.7%
Identity: 18%
PDB header:signaling protein
Chain: A: PDB Molecule:acyl carrier protein;
PDBTitle: toxoplasma gondii apicoplast-targeted acyl carrier protein

Phyre2
15 |
| d1f80d_ |

### PDB 1f80 chain D

Region: 81 - 103
Aligned: 23
Modelled: 23
Confidence: 37.6%
Identity: 30%
Fold: Acyl carrier protein-like
Superfamily: ACP-like
Family: Acyl-carrier protein (ACP)

Phyre2
16 |
| c3ce7A_ |

### PDB 3ce7 chain A

Region: 82 - 102
Aligned: 21
Modelled: 21
Confidence: 37.3%
Identity: 14%
PDB header:biosynthetic protein
Chain: A: PDB Molecule:specific mitochodrial acyl carrier protein;
PDBTitle: crystal structure of toxoplasma specific mitochodrial acyl2 carrier protein, 59.m03510

Phyre2
17 |
| c2ehtA_ |

### PDB 2eht chain A

Region: 81 - 102
Aligned: 22
Modelled: 22
Confidence: 36.3%
Identity: 27%
PDB header:lipid transport
Chain: A: PDB Molecule:acyl carrier protein;
PDBTitle: crystal structure of acyl carrier protein from aquifex aeolicus (form2 2)

Phyre2
18 |
| c2fvfA_ |

### PDB 2fvf chain A

Region: 81 - 102
Aligned: 22
Modelled: 22
Confidence: 32.8%
Identity: 23%
PDB header:biosynthetic protein
Chain: A: PDB Molecule:acyl carrier protein;
PDBTitle: structure of 10:0-acp (protein with docked fatty acid)

Phyre2
19 |
| c3ejbC_ |

### PDB 3ejb chain C

Region: 81 - 103
Aligned: 23
Modelled: 23
Confidence: 32.3%
Identity: 30%
PDB header:oxidoreductase/lipid transport
Chain: C: PDB Molecule:acyl carrier protein;
PDBTitle: crystal structure of p450bioi in complex with tetradecanoic2 acid ligated acyl carrier protein

Phyre2
20 |
| c2dnwA_ |

### PDB 2dnw chain A

Region: 81 - 102
Aligned: 22
Modelled: 22
Confidence: 31.9%
Identity: 18%
PDB header:transport protein
Chain: A: PDB Molecule:acyl carrier protein;
PDBTitle: solution structure of rsgi ruh-059, an acp domain of acyl2 carrier protein, mitochondrial [precursor] from human cdna

Phyre2
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47 |

Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | d1h99a1 |
|  | 99.9 | 8 | Fold:PTS-regulatory domain, PRD Superfamily:PTS-regulatory domain, PRD Family:PTS-regulatory domain, PRD
2 | d1h99a2 |
|  | 99.8 | 14 | Fold:PTS-regulatory domain, PRD Superfamily:PTS-regulatory domain, PRD Family:PTS-regulatory domain, PRD
3 | c3gwhB_ |
|  | 99.8 | 21 | PDB header:transcription Chain: B: PDB Molecule:transcriptional antiterminator (bglg family); PDBTitle: crystallographic ab initio protein solution far below atomic2 resolution
4 | c1h99A_ |
|  | 99.7 | 8 | PDB header:transcriptional antiterminator Chain: A: PDB Molecule:transcription antiterminator lict; PDBTitle: prd of lict antiterminator from bacillus subtilis
5 | c3sqnB_ |
|  | 98.7 | 7 | PDB header:transcription regulator Chain: B: PDB Molecule:conserved domain protein; PDBTitle: putative mga family transcriptional regulator from enterococcus2 faecalis
6 | c3nufB_ |
|  | 98.1 | 18 | PDB header:transcription regulator Chain: B: PDB Molecule:prd-containing transcription regulator; PDBTitle: crystal structure of a prd-containing transcription regulator2 (lsei_2718) from lactobacillus casei atcc 334 at 1.38 a resolution
7 | c2kciA_ |
|  | 57.3 | 14 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative acyl carrier protein; PDBTitle: solution nmr structure of gmet_2339 from geobacter2 metallireducens. northeast structural genomics consortium3 target gmr141
8 | c2jq4A_ |
|  | 56.3 | 27 | PDB header:structural genomics Chain: A: PDB Molecule:hypothetical protein atu2571; PDBTitle: complete resonance assignments and solution structure2 calculation of atc2521 (nesg id: att6) from agrobacterium3 tumefaciens
9 | d2jq4a1 |
|  | 56.3 | 27 | Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP)
10 | c3lmoA_ |
|  | 55.9 | 9 | PDB header:transferase Chain: A: PDB Molecule:specialized acyl carrier protein; PDBTitle: crystal structure of specialized acyl carrier protein2 (rpa2022) from rhodopseudomonas palustris, northeast3 structural genomics consortium target rpr324
11 | c3id6A_ |
|  | 42.4 | 5 | PDB header:transferase Chain: A: PDB Molecule:pre mrna splicing protein; PDBTitle: crystal structure of sulfolobus solfataricus nop5 (1-262) and2 fibrillarin complex
12 | c2l4bA_ |
|  | 40.0 | 26 | PDB header:transferase Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: solution structure of a putative acyl carrier protein from anaplasma2 phagocytophilum. seattle structural genomics center for infectious3 disease target anpha.01018.a
13 | c1x3oA_ |
|  | 38.8 | 35 | PDB header:lipid transport Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: crystal structure of the acyl carrier protein from thermus2 thermophilus hb8
14 | c2qnwA_ |
|  | 38.7 | 18 | PDB header:signaling protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: toxoplasma gondii apicoplast-targeted acyl carrier protein
15 | d1f80d_ |
|  | 37.6 | 30 | Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP)
16 | c3ce7A_ |
|  | 37.3 | 14 | PDB header:biosynthetic protein Chain: A: PDB Molecule:specific mitochodrial acyl carrier protein; PDBTitle: crystal structure of toxoplasma specific mitochodrial acyl2 carrier protein, 59.m03510
17 | c2ehtA_ |
|  | 36.3 | 27 | PDB header:lipid transport Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: crystal structure of acyl carrier protein from aquifex aeolicus (form2 2)
18 | c2fvfA_ |
|  | 32.8 | 23 | PDB header:biosynthetic protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: structure of 10:0-acp (protein with docked fatty acid)
19 | c3ejbC_ |
|  | 32.3 | 30 | PDB header:oxidoreductase/lipid transport Chain: C: PDB Molecule:acyl carrier protein; PDBTitle: crystal structure of p450bioi in complex with tetradecanoic2 acid ligated acyl carrier protein
20 | c2dnwA_ |
|  | 31.9 | 18 | PDB header:transport protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: solution structure of rsgi ruh-059, an acp domain of acyl2 carrier protein, mitochondrial [precursor] from human cdna
21 | c2fq2A_ |
| not modelled | 30.1 | 18 | PDB header:lipid transport Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: solution structure of minor conformation of holo-acyl2 carrier protein from malaria parasite plasmodium falciparum
22 | c2lkiA_ |
| not modelled | 29.5 | 32 | PDB header:lipid transport Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: solution nmr structure of holo acyl carrier protein ne2163 from2 nitrosomonas europaea. northeast structural genomics consortium3 target net1.
23 | c2cgqA_ |
| not modelled | 28.1 | 22 | PDB header:protein transport Chain: A: PDB Molecule:acyl carrier protein acpa; PDBTitle: a putative acyl carrier protein(rv0033) from mycobacterium2 tuberculosis
24 | c3id5E_ |
| not modelled | 27.7 | 5 | PDB header:transferase/ribosomal protein/rna Chain: E: PDB Molecule:pre mrna splicing protein; PDBTitle: crystal structure of sulfolobus solfataricus c/d rnp assembled with2 nop5, fibrillarin, l7ae and a split half c/d rna
25 | c2cnrA_ |
| not modelled | 26.7 | 9 | PDB header:lipid transport Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: structural studies on the interaction of scfas acp with2 acps
26 | c2amwA_ |
| not modelled | 25.6 | 32 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ne2163; PDBTitle: solution nmr structure of protein ne2163 from nitrosomonas europaea.2 northeast structural genomics consortium target net1.
27 | c2kwlA_ |
| not modelled | 25.4 | 18 | PDB header:lipid binding protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: solution structure of acyl carrier protein from borrelia burgdorferi
28 | d1t8ka_ |
| not modelled | 21.6 | 32 | Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP)
29 | d1klpa_ |
| not modelled | 20.8 | 5 | Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP)
30 | d2pnga1 |
| not modelled | 20.3 | 27 | Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP)
31 | d1nq4a_ |
| not modelled | 20.1 | 4 | Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP)
32 | d1or5a_ |
| not modelled | 19.5 | 17 | Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP)
33 | d1dv5a_ |
| not modelled | 19.4 | 18 | Fold:Acyl carrier protein-like Superfamily:ACP-like Family:apo-D-alanyl carrier protein
34 | d1vkua_ |
| not modelled | 18.8 | 32 | Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP)
35 | d1vlpa1 |
| not modelled | 17.7 | 21 | Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like
36 | d1ybea2 |
| not modelled | 16.1 | 16 | Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like
37 | d2af8a_ |
| not modelled | 14.2 | 10 | Fold:Acyl carrier protein-like Superfamily:ACP-like Family:Acyl-carrier protein (ACP)
38 | c2l3vA_ |
| not modelled | 14.1 | 21 | PDB header:lipid binding protein Chain: A: PDB Molecule:acyl carrier protein; PDBTitle: nmr structure of acyl carrier protein from brucella melitensis
39 | c1zxjB_ |
| not modelled | 12.7 | 22 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein mg377 homolog; PDBTitle: crystal structure of the hypthetical mycoplasma protein,2 mpn555
40 | d1d0qa_ |
| not modelled | 11.9 | 16 | Fold:Rubredoxin-like Superfamily:Zinc beta-ribbon Family:DNA primase zinc finger
41 | c2kr5A_ |
| not modelled | 11.2 | 8 | PDB header:transport protein Chain: A: PDB Molecule:aflatoxin biosynthesis polyketide synthase; PDBTitle: solution structure of an acyl carrier protein domain from fungal type2 i polyketide synthase
42 | d1t3ta1 |
| not modelled | 10.2 | 18 | Fold:RuvA C-terminal domain-like Superfamily:FGAM synthase PurL, linker domain Family:FGAM synthase PurL, linker domain
43 | d2prva1 |
| not modelled | 9.0 | 7 | Fold:SMI1/KNR4-like Superfamily:SMI1/KNR4-like Family:SMI1/KNR4-like
44 | c3d9wA_ |
| not modelled | 8.6 | 22 | PDB header:transferase Chain: A: PDB Molecule:putative acetyltransferase; PDBTitle: crystal structure analysis of nocardia farcinica arylamine2 n-acetyltransferase
45 | c3d5pB_ |
| not modelled | 7.6 | 14 | PDB header:gene regulation Chain: B: PDB Molecule:putative glucan synthesis regulator of smi1/knr4 family; PDBTitle: crystal structure of a putative glucan synthesis regulator of2 smi1/knr4 family (bf1740) from bacteroides fragilis nctc 9343 at 1.453 a resolution
46 | d1e2ta_ |
| not modelled | 7.2 | 35 | Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:Arylamine N-acetyltransferase
47 | d1w5ra1 |
| not modelled | 6.1 | 10 | Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:Arylamine N-acetyltransferase

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0