Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0AGF6
DateThu Jan 5 11:28:58 GMT 2012
Unique Job IDb3d53038500c20f7

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2gn0A_
Top template information
PDB header:lyase
Chain: A: PDB Molecule:threonine dehydratase catabolic;
PDBTitle: crystal structure of dimeric biodegradative threonine deaminase (tdcb)2 from salmonella typhimurium at 1.7 a resolution (triclinic form with3 one complete subunit built in alternate conformation)
Confidence and coverage
Confidence:100.0% Coverage: 98%
323 residues ( 98% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIR
Secondary structure 


























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Disorder  ???????




















































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   .........70.........80.........90.........100.........110.........120
Sequence  GAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDY
Secondary structure 

















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Disorder 










???













































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   .........130.........140.........150.........160.........170.........180
Sequence  SAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVI
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   .........190.........200.........210.........220.........230.........240
Sequence  VPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAASFHSGEITTHRTTGTLADGCDV
Secondary structure 























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?












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   .........250.........260.........270.........280.........290.........300
Sequence  SRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVVTEGAGALACAALLSGKLDQY
Secondary structure 










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????
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   .........310.........320.........
Sequence  IQNRKTVSIISGGNIDLSRVSQITGFVDA
Secondary structure 












SS confidence 




























Disorder  ?






















?????
Disorder confidence 




























 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2gn0 chain A

3D model

Region: 2 - 325
Aligned: 323
Modelled: 324
Confidence: 100.0%
Identity: 95%
PDB header:lyase
Chain: A: PDB Molecule:threonine dehydratase catabolic;
PDBTitle: crystal structure of dimeric biodegradative threonine deaminase (tdcb)2 from salmonella typhimurium at 1.7 a resolution (triclinic form with3 one complete subunit built in alternate conformation)

Phyre2

PDB 1tdj chain A

3D model

Region: 9 - 325
Aligned: 317
Modelled: 317
Confidence: 100.0%
Identity: 36%
PDB header:allostery
Chain: A: PDB Molecule:biosynthetic threonine deaminase;
PDBTitle: threonine deaminase (biosynthetic) from e. coli

Phyre2

PDB 1v71 chain A domain 1

3D model

Region: 9 - 325
Aligned: 315
Modelled: 317
Confidence: 100.0%
Identity: 39%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 3l6c chain A

3D model

Region: 5 - 320
Aligned: 315
Modelled: 316
Confidence: 100.0%
Identity: 33%
PDB header:isomerase
Chain: A: PDB Molecule:serine racemase;
PDBTitle: x-ray crystal structure of rat serine racemase in complex with2 malonate a potent inhibitor

Phyre2

PDB 3iau chain A

3D model

Region: 1 - 328
Aligned: 327
Modelled: 328
Confidence: 100.0%
Identity: 35%
PDB header:lyase
Chain: A: PDB Molecule:threonine deaminase;
PDBTitle: the structure of the processed form of threonine deaminase isoform 22 from solanum lycopersicum

Phyre2

PDB 1tdj chain A domain 1

3D model

Region: 18 - 328
Aligned: 311
Modelled: 311
Confidence: 100.0%
Identity: 36%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 1ve5 chain A domain 1

3D model

Region: 9 - 317
Aligned: 301
Modelled: 309
Confidence: 100.0%
Identity: 38%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 1pwh chain A

3D model

Region: 22 - 329
Aligned: 307
Modelled: 308
Confidence: 100.0%
Identity: 23%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 1p5j chain A

3D model

Region: 22 - 328
Aligned: 306
Modelled: 307
Confidence: 100.0%
Identity: 23%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 1p5j chain A

3D model

Region: 22 - 328
Aligned: 306
Modelled: 307
Confidence: 100.0%
Identity: 23%
PDB header:lyase
Chain: A: PDB Molecule:l-serine dehydratase;
PDBTitle: crystal structure analysis of human serine dehydratase

Phyre2

PDB 2rkb chain E

3D model

Region: 22 - 328
Aligned: 306
Modelled: 307
Confidence: 100.0%
Identity: 23%
PDB header:lyase
Chain: E: PDB Molecule:serine dehydratase-like;
PDBTitle: serine dehydratase like-1 from human cancer cells

Phyre2

PDB 3r0z chain A

3D model

Region: 4 - 324
Aligned: 318
Modelled: 321
Confidence: 100.0%
Identity: 19%
PDB header:lyase
Chain: A: PDB Molecule:d-serine dehydratase;
PDBTitle: crystal structure of apo d-serine deaminase from salmonella2 typhimurium

Phyre2

PDB 3pc3 chain A

3D model

Region: 21 - 320
Aligned: 292
Modelled: 300
Confidence: 100.0%
Identity: 20%
PDB header:lyase
Chain: A: PDB Molecule:cg1753, isoform a;
PDBTitle: full length structure of cystathionine beta-synthase from drosophila2 in complex with aminoacrylate

Phyre2

PDB 1ve1 chain A domain 1

3D model

Region: 20 - 313
Aligned: 281
Modelled: 294
Confidence: 100.0%
Identity: 20%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 2pqm chain A

3D model

Region: 18 - 313
Aligned: 284
Modelled: 296
Confidence: 100.0%
Identity: 19%
PDB header:lyase
Chain: A: PDB Molecule:cysteine synthase;
PDBTitle: crystal structure of cysteine synthase (oass) from entamoeba2 histolytica at 1.86 a resolution

Phyre2

PDB 1z7w chain A domain 1

3D model

Region: 18 - 320
Aligned: 291
Modelled: 294
Confidence: 100.0%
Identity: 22%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 1jbq chain A

3D model

Region: 20 - 320
Aligned: 292
Modelled: 297
Confidence: 100.0%
Identity: 22%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 1jbq chain D

3D model

Region: 20 - 320
Aligned: 292
Modelled: 297
Confidence: 100.0%
Identity: 22%
PDB header:lyase
Chain: D: PDB Molecule:cystathionine beta-synthase;
PDBTitle: structure of human cystathionine beta-synthase: a unique pyridoxal 5'-2 phosphate dependent hemeprotein

Phyre2

PDB 2d1f chain A

3D model

Region: 20 - 329
Aligned: 305
Modelled: 310
Confidence: 100.0%
Identity: 23%
PDB header:lyase
Chain: A: PDB Molecule:threonine synthase;
PDBTitle: structure of mycobacterium tuberculosis threonine synthase

Phyre2

PDB 1x1q chain A

3D model

Region: 1 - 325
Aligned: 323
Modelled: 320
Confidence: 100.0%
Identity: 21%
PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase beta chain;
PDBTitle: crystal structure of tryptophan synthase beta chain from thermus2 thermophilus hb8

Phyre2
1

c2gn0A_
2

c1tdjA_
3

d1v71a1
4

c3l6cA_
5

c3iauA_
6

d1tdja1
7

d1ve5a1
8

d1pwha_
9

d1p5ja_
10

c1p5jA_
11

c2rkbE_
12

c3r0zA_
13

c3pc3A_
14

d1ve1a1
15

c2pqmA_
16

d1z7wa1
17

d1jbqa_
18

c1jbqD_
19

c2d1fA_
20

c1x1qA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2gn0A_



100.0 95 PDB header:lyase
Chain: A: PDB Molecule:threonine dehydratase catabolic;
PDBTitle: crystal structure of dimeric biodegradative threonine deaminase (tdcb)2 from salmonella typhimurium at 1.7 a resolution (triclinic form with3 one complete subunit built in alternate conformation)
2c1tdjA_



100.0 36 PDB header:allostery
Chain: A: PDB Molecule:biosynthetic threonine deaminase;
PDBTitle: threonine deaminase (biosynthetic) from e. coli
3d1v71a1



100.0 39 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
4c3l6cA_



100.0 33 PDB header:isomerase
Chain: A: PDB Molecule:serine racemase;
PDBTitle: x-ray crystal structure of rat serine racemase in complex with2 malonate a potent inhibitor
5c3iauA_



100.0 35 PDB header:lyase
Chain: A: PDB Molecule:threonine deaminase;
PDBTitle: the structure of the processed form of threonine deaminase isoform 22 from solanum lycopersicum
6d1tdja1



100.0 36 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
7d1ve5a1



100.0 38 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
8d1pwha_



100.0 23 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
9d1p5ja_



100.0 23 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
10c1p5jA_



100.0 23 PDB header:lyase
Chain: A: PDB Molecule:l-serine dehydratase;
PDBTitle: crystal structure analysis of human serine dehydratase
11c2rkbE_



100.0 23 PDB header:lyase
Chain: E: PDB Molecule:serine dehydratase-like;
PDBTitle: serine dehydratase like-1 from human cancer cells
12c3r0zA_



100.0 19 PDB header:lyase
Chain: A: PDB Molecule:d-serine dehydratase;
PDBTitle: crystal structure of apo d-serine deaminase from salmonella2 typhimurium
13c3pc3A_



100.0 20 PDB header:lyase
Chain: A: PDB Molecule:cg1753, isoform a;
PDBTitle: full length structure of cystathionine beta-synthase from drosophila2 in complex with aminoacrylate
14d1ve1a1



100.0 20 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
15c2pqmA_



100.0 19 PDB header:lyase
Chain: A: PDB Molecule:cysteine synthase;
PDBTitle: crystal structure of cysteine synthase (oass) from entamoeba2 histolytica at 1.86 a resolution
16d1z7wa1



100.0 22 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
17d1jbqa_



100.0 22 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
18c1jbqD_



100.0 22 PDB header:lyase
Chain: D: PDB Molecule:cystathionine beta-synthase;
PDBTitle: structure of human cystathionine beta-synthase: a unique pyridoxal 5'-2 phosphate dependent hemeprotein
19c2d1fA_



100.0 23 PDB header:lyase
Chain: A: PDB Molecule:threonine synthase;
PDBTitle: structure of mycobacterium tuberculosis threonine synthase
20c1x1qA_



100.0 21 PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase beta chain;
PDBTitle: crystal structure of tryptophan synthase beta chain from thermus2 thermophilus hb8
21d2bhsa1



not modelled 100.0 21 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
22d1v8za1



not modelled 100.0 20 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
23c2zsjB_



not modelled 100.0 24 PDB header:lyase
Chain: B: PDB Molecule:threonine synthase;
PDBTitle: crystal structure of threonine synthase from aquifex aeolicus vf5
24d1wkva1



not modelled 100.0 18 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
25d1qopb_



not modelled 100.0 19 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
26c3dwgA_



not modelled 100.0 15 PDB header:transferase
Chain: A: PDB Molecule:cysteine synthase b;
PDBTitle: crystal structure of a sulfur carrier protein complex found in the2 cysteine biosynthetic pathway of mycobacterium tuberculosis
27d1v7ca_



not modelled 100.0 23 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
28c2q3bA_



not modelled 100.0 20 PDB header:transferase
Chain: A: PDB Molecule:cysteine synthase a;
PDBTitle: 1.8 a resolution crystal structure of o-acetylserine sulfhydrylase2 (oass) holoenzyme from mycobacterium tuberculosis
29d1o58a_



not modelled 100.0 19 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
30d1y7la1



not modelled 100.0 21 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
31d1fcja_



not modelled 100.0 22 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
32c2eguA_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:cysteine synthase;
PDBTitle: crystal structure of o-acetylserine sulfhydrase from geobacillus2 kaustophilus hta426
33d1e5xa_



not modelled 100.0 19 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
34c2o2jA_



not modelled 100.0 24 PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase beta chain;
PDBTitle: mycobacterium tuberculosis tryptophan synthase beta chain2 dimer (apoform)
35d1j0aa_



not modelled 100.0 15 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
36d1f2da_



not modelled 100.0 15 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
37d1tyza_



not modelled 100.0 15 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
38d1vb3a1



not modelled 100.0 18 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
39d1kl7a_



not modelled 100.0 15 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
40d1vp8a_



not modelled 94.8 19 Fold:Pyruvate kinase C-terminal domain-like
Superfamily:PK C-terminal domain-like
Family:MTH1675-like
41d1t57a_



not modelled 93.4 18 Fold:Pyruvate kinase C-terminal domain-like
Superfamily:PK C-terminal domain-like
Family:MTH1675-like
42d1xgka_



not modelled 93.3 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
43c3iupB_



not modelled 92.9 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nadph:quinone oxidoreductase;
PDBTitle: crystal structure of putative nadph:quinone oxidoreductase2 (yp_296108.1) from ralstonia eutropha jmp134 at 1.70 a resolution
44d1bg6a2



not modelled 90.8 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
45d1o8ca2



not modelled 89.6 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
46d1c1da1



not modelled 86.2 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
47d1ml4a2



not modelled 86.0 15 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
48d1cdoa2



not modelled 85.7 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
49d1o89a2



not modelled 84.4 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
50c3eywA_



not modelled 80.3 13 PDB header:transport protein
Chain: A: PDB Molecule:c-terminal domain of glutathione-regulated potassium-efflux
PDBTitle: crystal structure of the c-terminal domain of e. coli kefc in complex2 with keff
51c2p4hX_



not modelled 79.3 9 PDB header:plant protein
Chain: X: PDB Molecule:vestitone reductase;
PDBTitle: crystal structure of vestitone reductase from alfalfa2 (medicago sativa l.)
52d1l7da1



not modelled 78.8 6 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
53d1wvga1



not modelled 78.2 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
54c3s8mA_



not modelled 77.5 10 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-acp reductase;
PDBTitle: the crystal structure of fabv
55c3c1oA_



not modelled 74.5 8 PDB header:oxidoreductase
Chain: A: PDB Molecule:eugenol synthase;
PDBTitle: the multiple phenylpropene synthases in both clarkia2 breweri and petunia hybrida represent two distinct lineages
56d1p0fa2



not modelled 73.7 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
57d1ekxa2



not modelled 73.3 15 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
58c3ezlA_



not modelled 73.0 9 PDB header:oxidoreductase
Chain: A: PDB Molecule:acetoacetyl-coa reductase;
PDBTitle: crystal structure of acetyacetyl-coa reductase from2 burkholderia pseudomallei 1710b
59c1ml4A_



not modelled 70.4 14 PDB header:transferase
Chain: A: PDB Molecule:aspartate transcarbamoylase;
PDBTitle: the pala-liganded aspartate transcarbamoylase catalytic subunit from2 pyrococcus abyssi
60c2qx7A_



not modelled 70.3 13 PDB header:plant protein
Chain: A: PDB Molecule:eugenol synthase 1;
PDBTitle: structure of eugenol synthase from ocimum basilicum
61c3krtC_



not modelled 70.3 12 PDB header:oxidoreductase
Chain: C: PDB Molecule:crotonyl coa reductase;
PDBTitle: crystal structure of putative crotonyl coa reductase from streptomyces2 coelicolor a3(2)
62d1fl2a1



not modelled 69.7 19 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
63c3grkE_



not modelled 68.8 16 PDB header:oxidoreductase
Chain: E: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of short chain dehydrogenase reductase2 sdr glucose-ribitol dehydrogenase from brucella melitensis
64d1hyua1



not modelled 68.6 13 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
65d1tt7a2



not modelled 65.7 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
66d1pvva2



not modelled 65.5 22 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
67c3uf0A_



not modelled 65.2 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of a putative nad(p) dependent gluconate 5-2 dehydrogenase from beutenbergia cavernae(efi target efi-502044) with3 bound nadp (low occupancy)
68d1otha2



not modelled 64.1 17 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
69c2xecD_



not modelled 63.5 20 PDB header:isomerase
Chain: D: PDB Molecule:putative maleate isomerase;
PDBTitle: nocardia farcinica maleate cis-trans isomerase bound to2 tris
70d1vdca1



not modelled 63.3 11 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
71c1n7gB_



not modelled 63.2 9 PDB header:lyase
Chain: B: PDB Molecule:gdp-d-mannose-4,6-dehydratase;
PDBTitle: crystal structure of the gdp-mannose 4,6-dehydratase2 ternary complex with nadph and gdp-rhamnose.
72d1d1ta2



not modelled 62.2 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
73d1rkxa_



not modelled 61.6 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
74d1trba1



not modelled 61.5 6 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
75d1qyda_



not modelled 61.3 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
76c3i5mA_



not modelled 60.8 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative leucoanthocyanidin reductase 1;
PDBTitle: structure of the apo form of leucoanthocyanidin reductase from vitis2 vinifera
77d1nhpa2



not modelled 59.6 15 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
78c3i4fD_



not modelled 58.9 10 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier protein] reductase;
PDBTitle: structure of putative 3-oxoacyl-reductase from bacillus thuringiensis
79c2q2qG_



not modelled 58.8 18 PDB header:oxidoreductase
Chain: G: PDB Molecule:beta-d-hydroxybutyrate dehydrogenase;
PDBTitle: structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida
80c1pjtB_



not modelled 57.4 12 PDB header:transferase/oxidoreductase/lyase
Chain: B: PDB Molecule:siroheme synthase;
PDBTitle: the structure of the ser128ala point-mutant variant of cysg,2 the multifunctional3 methyltransferase/dehydrogenase/ferrochelatase for4 siroheme synthesis
81d3lada1



not modelled 56.9 22 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
82d2hmva1



not modelled 55.6 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Potassium channel NAD-binding domain
83d1e3ia2



not modelled 54.7 9 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
84d1n7ha_



not modelled 54.5 9 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
85c2rghA_



not modelled 54.5 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:alpha-glycerophosphate oxidase;
PDBTitle: structure of alpha-glycerophosphate oxidase from2 streptococcus sp.: a template for the mitochondrial alpha-3 glycerophosphate dehydrogenase
86c2g1uA_



not modelled 53.8 19 PDB header:transport protein
Chain: A: PDB Molecule:hypothetical protein tm1088a;
PDBTitle: crystal structure of a putative transport protein (tm1088a) from2 thermotoga maritima at 1.50 a resolution
87d1xa0a2



not modelled 53.7 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
88d2i0za1



not modelled 53.7 15 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:HI0933 N-terminal domain-like
89c2qioA_



not modelled 53.6 12 PDB header:unknown function
Chain: A: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: x-ray structure of enoyl-acyl carrier protein reductase from bacillus2 anthracis with triclosan
90d2jhfa2



not modelled 53.5 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
91c3r3sD_



not modelled 53.5 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:oxidoreductase;
PDBTitle: structure of the ygha oxidoreductase from salmonella enterica
92c1boiA_



not modelled 53.4 16 PDB header:transferase
Chain: A: PDB Molecule:rhodanese;
PDBTitle: n-terminally truncated rhodanese
93d1llua2



not modelled 53.3 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
94c2exxB_



not modelled 53.2 18 PDB header:unknown function
Chain: B: PDB Molecule:hscarg protein;
PDBTitle: crystal structure of hscarg from homo sapiens in complex with nadp
95c3allA_



not modelled 52.8 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase;
PDBTitle: crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid2 oxygenase, mutant y270a
96d1lvla1



not modelled 52.4 19 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
97c2hk8B_



not modelled 52.1 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:shikimate dehydrogenase;
PDBTitle: crystal structure of shikimate dehydrogenase from aquifex2 aeolicus at 2.35 angstrom resolution
98d1u3wa2



not modelled 51.5 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
99d1dxla1



not modelled 51.4 22 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
100c3d3kD_



not modelled 51.2 13 PDB header:protein binding
Chain: D: PDB Molecule:enhancer of mrna-decapping protein 3;
PDBTitle: crystal structure of human edc3p
101c1ulzA_



not modelled 51.0 20 PDB header:ligase
Chain: A: PDB Molecule:pyruvate carboxylase n-terminal domain;
PDBTitle: crystal structure of the biotin carboxylase subunit of pyruvate2 carboxylase
102c3q98A_



not modelled 49.5 14 PDB header:transferase
Chain: A: PDB Molecule:transcarbamylase;
PDBTitle: structure of ygew encoded protein from e. coli
103c3orqA_



not modelled 49.2 13 PDB header:ligase,biosynthetic protein
Chain: A: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide synthetase;
PDBTitle: crystal structure of n5-carboxyaminoimidazole synthetase from2 staphylococcus aureus complexed with adp
104c3kzvA_



not modelled 48.8 7 PDB header:oxidoreductase
Chain: A: PDB Molecule:uncharacterized oxidoreductase yir035c;
PDBTitle: the crystal structure of a cytoplasmic protein with unknown function2 from saccharomyces cerevisiae
105d1ebda1



not modelled 48.7 22 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
106c3d4oA_



not modelled 48.5 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase subunit a;
PDBTitle: crystal structure of dipicolinate synthase subunit a (np_243269.1)2 from bacillus halodurans at 2.10 a resolution
107d1pg5a2



not modelled 47.9 2 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
108d1kola2



not modelled 47.6 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
109d1ulua_



not modelled 47.3 9 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
110c3ijrF_



not modelled 47.0 12 PDB header:oxidoreductase
Chain: F: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family;
PDBTitle: 2.05 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor' in complex3 with nad+
111d1rpna_



not modelled 47.0 6 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
112d1lpfa1



not modelled 46.8 26 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
113d1vlva2



not modelled 46.8 10 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
114c2ax3A_



not modelled 46.5 17 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein tm0922;
PDBTitle: crystal structure of a putative carbohydrate kinase (tm0922) from2 thermotoga maritima msb8 at 2.25 a resolution
115d1im5a_



not modelled 46.5 10 Fold:Isochorismatase-like hydrolases
Superfamily:Isochorismatase-like hydrolases
Family:Isochorismatase-like hydrolases
116d1gega_



not modelled 46.1 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
117d1ae1a_



not modelled 45.6 7 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
118d1ja9a_



not modelled 45.4 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
119c2bryA_



not modelled 45.3 21 PDB header:transport
Chain: A: PDB Molecule:nedd9 interacting protein with calponin homology
PDBTitle: crystal structure of the native monooxygenase domain of2 mical at 1.45 a resolution
120c3o93A_



not modelled 44.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:nicotinamidase;
PDBTitle: high resolution crystal structures of streptococcus pneumoniae2 nicotinamidase with trapped intermediates provide insights into3 catalytic mechanism and inhibition by aldehydes

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0