Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP30143
DateThu Jan 5 11:46:07 GMT 2012
Unique Job IDad74ab9e09d57c49

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3giaA_
Top template information
PDB header:transport protein
Chain: A: PDB Molecule:uncharacterized protein mj0609;
PDBTitle: crystal structure of apct transporter
Confidence and coverage
Confidence: 99.9% Coverage: 75%
357 residues ( 75% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MPDFFSFINSVLWGSVMIYLLFGAGCWFTFRTGFVQFRYIRQFGKSLKNSIHPQPGGLTS
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??????????

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   .........70.........80.........90.........100.........110.........120
Sequence  FQSLCTSLAARVGSGNLAGVALAITAGGPGAVFWMWVAAFIGMATSFAECSLAQLYKERD
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   .........130.........140.........150.........160.........170.........180
Sequence  VNGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGIIFSGVQANAVARALSFSFDFPPLV
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   .........190.........200.........210.........220.........230.........240
Sequence  TGIILAVFTLLAITRGLHGVARLMQGFVPLMAIIWVLTSLVICVMNIGQLPHVIWSIFES
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   .........250.........260.........270.........280.........290.........300
Sequence  AFGWQEAAGGAAGYTLSQAITNGFQRSMFSNEAGMGSTPNAAAAAASWPPHPAAQGIVQM
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?



?????????









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   .........310.........320.........330.........340.........350.........360
Sequence  IGIFIDTLVICTASAMLILLAGNGTTYMPLEGIQLIQKAMRVLMGSWGAEFVTLVVILFA
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   .........370.........380.........390.........400.........410.........420
Sequence  FSSIVANYIYAENNLFFLRLNNPKAIWCLRICTFATVIGGTLLSLPLMWQLADIIMACMA
Secondary structure 





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?
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   .........430.........440.........450.........460.........470......
Sequence  ITNLTAILLLSPVVHTIASDYLRQRKLGVRPVFDPLRYPDIGRQLSPDAWDDVSQE
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???????















????????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3gia chain A

3D model

Region: 54 - 441
Aligned: 357
Modelled: 357
Confidence: 99.9%
Identity: 12%
PDB header:transport protein
Chain: A: PDB Molecule:uncharacterized protein mj0609;
PDBTitle: crystal structure of apct transporter

Phyre2

PDB 2jln chain A

3D model

Region: 48 - 454
Aligned: 383
Modelled: 392
Confidence: 99.8%
Identity: 8%
PDB header:membrane protein
Chain: A: PDB Molecule:mhp1;
PDBTitle: structure of mhp1, a nucleobase-cation-symport-1 family2 transporter

Phyre2

PDB 3lrc chain C

3D model

Region: 54 - 448
Aligned: 344
Modelled: 344
Confidence: 99.6%
Identity: 15%
PDB header:transport protein
Chain: C: PDB Molecule:arginine/agmatine antiporter;
PDBTitle: structure of e. coli adic (p1)

Phyre2

PDB 3dh4 chain A

3D model

Region: 38 - 428
Aligned: 382
Modelled: 366
Confidence: 99.0%
Identity: 10%
PDB header:transport protein
Chain: A: PDB Molecule:sodium/glucose cotransporter;
PDBTitle: crystal structure of sodium/sugar symporter with bound galactose from2 vibrio parahaemolyticus

Phyre2

PDB 2xq2 chain A

3D model

Region: 17 - 438
Aligned: 383
Modelled: 383
Confidence: 99.0%
Identity: 11%
PDB header:transport protein
Chain: A: PDB Molecule:sodium/glucose cotransporter;
PDBTitle: structure of the k294a mutant of vsglt

Phyre2

PDB 2a65 chain A domain 1

3D model

Region: 59 - 458
Aligned: 388
Modelled: 388
Confidence: 98.7%
Identity: 15%
Fold: SNF-like
Superfamily: SNF-like
Family: SNF-like

Phyre2

PDB 2w8a chain C

3D model

Region: 2 - 447
Aligned: 423
Modelled: 435
Confidence: 96.0%
Identity: 14%
PDB header:membrane protein
Chain: C: PDB Molecule:glycine betaine transporter betp;
PDBTitle: crystal structure of the sodium-coupled glycine betaine2 symporter betp from corynebacterium glutamicum with bound3 substrate

Phyre2

PDB 3hfx chain A

3D model

Region: 2 - 440
Aligned: 416
Modelled: 416
Confidence: 94.9%
Identity: 11%
PDB header:transport protein
Chain: A: PDB Molecule:l-carnitine/gamma-butyrobetaine antiporter;
PDBTitle: crystal structure of carnitine transporter

Phyre2

PDB 1c8z chain A

3D model

Region: 58 - 70
Aligned: 13
Modelled: 13
Confidence: 48.2%
Identity: 23%
Fold: Tubby C-terminal domain-like
Superfamily: Tubby C-terminal domain-like
Family: Transcriptional factor tubby, C-terminal domain

Phyre2

PDB 2h2w chain A

3D model

Region: 437 - 472
Aligned: 36
Modelled: 36
Confidence: 30.8%
Identity: 14%
PDB header:transferase
Chain: A: PDB Molecule:homoserine o-succinyltransferase;
PDBTitle: crystal structure of homoserine o-succinyltransferase (ec 2.3.1.46)2 (homoserine o-transsuccinylase) (hts) (tm0881) from thermotoga3 maritima at 2.52 a resolution

Phyre2

PDB 2ghr chain A domain 1

3D model

Region: 437 - 472
Aligned: 36
Modelled: 36
Confidence: 28.3%
Identity: 17%
Fold: Flavodoxin-like
Superfamily: Class I glutamine amidotransferase-like
Family: HTS-like

Phyre2

PDB 1ml8 chain A

3D model

Region: 50 - 74
Aligned: 25
Modelled: 25
Confidence: 26.9%
Identity: 0%
Fold: OsmC-like
Superfamily: OsmC-like
Family: YhfA-like

Phyre2

PDB 1vla chain A

3D model

Region: 53 - 74
Aligned: 22
Modelled: 21
Confidence: 22.7%
Identity: 14%
Fold: OsmC-like
Superfamily: OsmC-like
Family: YhfA-like

Phyre2

PDB 1htj chain F

3D model

Region: 432 - 468
Aligned: 37
Modelled: 37
Confidence: 22.4%
Identity: 19%
Fold: Regulator of G-protein signaling, RGS
Superfamily: Regulator of G-protein signaling, RGS
Family: Regulator of G-protein signaling, RGS

Phyre2

PDB 1htj chain F

3D model

Region: 432 - 468
Aligned: 37
Modelled: 37
Confidence: 22.4%
Identity: 19%
PDB header:signaling protein
Chain: F: PDB Molecule:kiaa0380;
PDBTitle: structure of the rgs-like domain from pdz-rhogef

Phyre2

PDB 2knc chain B

3D model

Region: 408 - 459
Aligned: 52
Modelled: 52
Confidence: 19.2%
Identity: 13%
PDB header:cell adhesion
Chain: B: PDB Molecule:integrin beta-3;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex

Phyre2

PDB 2hxv chain A domain 2

3D model

Region: 429 - 449
Aligned: 21
Modelled: 21
Confidence: 18.4%
Identity: 10%
Fold: Cytidine deaminase-like
Superfamily: Cytidine deaminase-like
Family: Deoxycytidylate deaminase-like

Phyre2

PDB 1fft chain B domain 2

3D model

Region: 87 - 125
Aligned: 39
Modelled: 39
Confidence: 17.5%
Identity: 8%
Fold: Transmembrane helix hairpin
Superfamily: Cytochrome c oxidase subunit II-like, transmembrane region
Family: Cytochrome c oxidase subunit II-like, transmembrane region

Phyre2

PDB 1lql chain E

3D model

Region: 52 - 74
Aligned: 23
Modelled: 23
Confidence: 16.8%
Identity: 22%
PDB header:unknown function
Chain: E: PDB Molecule:osmotical inducible protein c like family;
PDBTitle: crystal structure of osmc like protein from mycoplasma2 pneumoniae

Phyre2

PDB 1lql chain A

3D model

Region: 52 - 74
Aligned: 23
Modelled: 23
Confidence: 16.8%
Identity: 22%
Fold: OsmC-like
Superfamily: OsmC-like
Family: Ohr/OsmC resistance proteins

Phyre2
1

c3giaA_
2

c2jlnA_
3

c3lrcC_
4

c3dh4A_
5

c2xq2A_
6

d2a65a1
7

c2w8aC_
8

c3hfxA_
9

d1c8za_
10

c2h2wA_
11

d2ghra1
12

d1ml8a_
13

d1vlaa_
14

d1htjf_
15

c1htjF_
16

c2kncB_
17

d2hxva2
18

d1fftb2
19

c1lqlE_
20

d1lqla_
21



22



23



24



25



26



27



28



29



30



31



32



33



34



35



36



37



38



39



40



41



42



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47



48



49



50



51



52



53



54



55



56



57






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3giaA_



99.9 12 PDB header:transport protein
Chain: A: PDB Molecule:uncharacterized protein mj0609;
PDBTitle: crystal structure of apct transporter
2c2jlnA_



99.8 8 PDB header:membrane protein
Chain: A: PDB Molecule:mhp1;
PDBTitle: structure of mhp1, a nucleobase-cation-symport-1 family2 transporter
3c3lrcC_



99.6 15 PDB header:transport protein
Chain: C: PDB Molecule:arginine/agmatine antiporter;
PDBTitle: structure of e. coli adic (p1)
4c3dh4A_



99.0 10 PDB header:transport protein
Chain: A: PDB Molecule:sodium/glucose cotransporter;
PDBTitle: crystal structure of sodium/sugar symporter with bound galactose from2 vibrio parahaemolyticus
5c2xq2A_



99.0 11 PDB header:transport protein
Chain: A: PDB Molecule:sodium/glucose cotransporter;
PDBTitle: structure of the k294a mutant of vsglt
6d2a65a1



98.7 15 Fold:SNF-like
Superfamily:SNF-like
Family:SNF-like
7c2w8aC_



96.0 14 PDB header:membrane protein
Chain: C: PDB Molecule:glycine betaine transporter betp;
PDBTitle: crystal structure of the sodium-coupled glycine betaine2 symporter betp from corynebacterium glutamicum with bound3 substrate
8c3hfxA_



94.9 11 PDB header:transport protein
Chain: A: PDB Molecule:l-carnitine/gamma-butyrobetaine antiporter;
PDBTitle: crystal structure of carnitine transporter
9d1c8za_



48.2 23 Fold:Tubby C-terminal domain-like
Superfamily:Tubby C-terminal domain-like
Family:Transcriptional factor tubby, C-terminal domain
10c2h2wA_



30.8 14 PDB header:transferase
Chain: A: PDB Molecule:homoserine o-succinyltransferase;
PDBTitle: crystal structure of homoserine o-succinyltransferase (ec 2.3.1.46)2 (homoserine o-transsuccinylase) (hts) (tm0881) from thermotoga3 maritima at 2.52 a resolution
11d2ghra1



28.3 17 Fold:Flavodoxin-like
Superfamily:Class I glutamine amidotransferase-like
Family:HTS-like
12d1ml8a_



26.9 0 Fold:OsmC-like
Superfamily:OsmC-like
Family:YhfA-like
13d1vlaa_



22.7 14 Fold:OsmC-like
Superfamily:OsmC-like
Family:YhfA-like
14d1htjf_



22.4 19 Fold:Regulator of G-protein signaling, RGS
Superfamily:Regulator of G-protein signaling, RGS
Family:Regulator of G-protein signaling, RGS
15c1htjF_



22.4 19 PDB header:signaling protein
Chain: F: PDB Molecule:kiaa0380;
PDBTitle: structure of the rgs-like domain from pdz-rhogef
16c2kncB_



19.2 13 PDB header:cell adhesion
Chain: B: PDB Molecule:integrin beta-3;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex
17d2hxva2



18.4 10 Fold:Cytidine deaminase-like
Superfamily:Cytidine deaminase-like
Family:Deoxycytidylate deaminase-like
18d1fftb2



17.5 8 Fold:Transmembrane helix hairpin
Superfamily:Cytochrome c oxidase subunit II-like, transmembrane region
Family:Cytochrome c oxidase subunit II-like, transmembrane region
19c1lqlE_



16.8 22 PDB header:unknown function
Chain: E: PDB Molecule:osmotical inducible protein c like family;
PDBTitle: crystal structure of osmc like protein from mycoplasma2 pneumoniae
20d1lqla_



16.8 22 Fold:OsmC-like
Superfamily:OsmC-like
Family:Ohr/OsmC resistance proteins
21c2lkgA_



not modelled 16.8 25 PDB header:signaling protein
Chain: A: PDB Molecule:acetylcholine receptor;
PDBTitle: wsa major conformation
22c2k21A_



not modelled 16.6 18 PDB header:membrane protein
Chain: A: PDB Molecule:potassium voltage-gated channel subfamily e
PDBTitle: nmr structure of human kcne1 in lmpg micelles at ph 6.0 and2 40 degree c
23d1z3aa1



not modelled 15.4 23 Fold:Cytidine deaminase-like
Superfamily:Cytidine deaminase-like
Family:Deoxycytidylate deaminase-like
24d1qwia_



not modelled 15.3 14 Fold:OsmC-like
Superfamily:OsmC-like
Family:Ohr/OsmC resistance proteins
25c2egtA_



not modelled 14.6 23 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein aq_1549;
PDBTitle: crystal structure of hypothetical protein (aq1549) from aquifex2 aeolicus
26d2pn2a1



not modelled 13.5 20 Fold:OsmC-like
Superfamily:OsmC-like
Family:Ohr/OsmC resistance proteins
27d2b3ja1



not modelled 12.9 11 Fold:Cytidine deaminase-like
Superfamily:Cytidine deaminase-like
Family:Deoxycytidylate deaminase-like
28c2be6F_



not modelled 12.3 19 PDB header:membrane protein
Chain: F: PDB Molecule:voltage-dependent l-type calcium channel alpha-1c subunit;
PDBTitle: 2.0 a crystal structure of the cav1.2 iq domain-ca/cam complex
29c2bjoA_



not modelled 11.5 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:organic hydroperoxide resistance protein ohrb;
PDBTitle: crystal structure of the organic hydroperoxide resistance2 protein ohrb of bacillus subtilis
30c3m4wH_



not modelled 10.6 44 PDB header:signaling protein/signaling protein
Chain: H: PDB Molecule:sigma-e factor negative regulatory protein;
PDBTitle: structural basis for the negative regulation of bacterial stress2 response by rseb
31c1shzF_



not modelled 8.7 15 PDB header:signaling protein
Chain: F: PDB Molecule:rho guanine nucleotide exchange factor 1;
PDBTitle: crystal structure of the p115rhogef rgrgs domain in a2 complex with galpha(13):galpha(i1) chimera
32c3eerA_



not modelled 8.4 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:organic hydroperoxide resistance protein, putative;
PDBTitle: high resolution structure of putative organic hydroperoxide resistance2 protein from vibrio cholerae o1 biovar eltor str. n16961
33d2b3za2



not modelled 8.2 15 Fold:Cytidine deaminase-like
Superfamily:Cytidine deaminase-like
Family:Deoxycytidylate deaminase-like
34d2onfa1



not modelled 8.1 17 Fold:OsmC-like
Superfamily:OsmC-like
Family:Ohr/OsmC resistance proteins
35c2kncA_



not modelled 7.9 12 PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-iib;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex
36d2opla1



not modelled 7.7 13 Fold:OsmC-like
Superfamily:OsmC-like
Family:Ohr/OsmC resistance proteins
37c2latA_



not modelled 7.4 19 PDB header:membrane protein
Chain: A: PDB Molecule:dolichyl-diphosphooligosaccharide--protein
PDBTitle: solution structure of a human minimembrane protein ost4
38d2d7va1



not modelled 7.4 4 Fold:OsmC-like
Superfamily:OsmC-like
Family:Ohr/OsmC resistance proteins
39c2pjwH_



not modelled 7.0 24 PDB header:endocytosis/exocytosis
Chain: H: PDB Molecule:uncharacterized protein yhl002w;
PDBTitle: the vps27/hse1 complex is a gat domain-based scaffold for2 ubiquitin-dependent sorting
40d2fika2



not modelled 6.9 20 Fold:MHC antigen-recognition domain
Superfamily:MHC antigen-recognition domain
Family:MHC antigen-recognition domain
41c1k8vA_



not modelled 6.9 45 PDB header:unknown function
Chain: A: PDB Molecule:neuropeptide f;
PDBTitle: the nmr-derived conformation of neuropeptide f from2 moniezia expansa
42d2o34a1



not modelled 6.8 16 Fold:T-fold
Superfamily:ApbE-like
Family:DVU1097-like
43c1iflA_



not modelled 6.6 16 PDB header:virus
Chain: A: PDB Molecule:inovirus;
PDBTitle: molecular models and structural comparisons of native and2 mutant class i filamentous bacteriophages ff (fd, f1, m13),3 if1 and ike
44c2ql8A_



not modelled 6.6 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative redox protein;
PDBTitle: crystal structure of a putative redox protein (lsei_0423) from2 lactobacillus casei atcc 334 at 1.50 a resolution
45c2qy6A_



not modelled 6.4 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:upf0209 protein yfck;
PDBTitle: crystal structure of the n-terminal domain of upf0209 protein yfck2 from escherichia coli o157:h7
46c2kluA_



not modelled 6.3 30 PDB header:immune system, membrane protein
Chain: A: PDB Molecule:t-cell surface glycoprotein cd4;
PDBTitle: nmr structure of the transmembrane and cytoplasmic domains2 of human cd4
47c3mk7F_



not modelled 6.1 21 PDB header:oxidoreductase
Chain: F: PDB Molecule:cytochrome c oxidase, cbb3-type, subunit p;
PDBTitle: the structure of cbb3 cytochrome oxidase
48c3cjeA_



not modelled 6.1 9 PDB header:oxidoreductase
Chain: A: PDB Molecule:osmc-like protein;
PDBTitle: crystal structure of an osmc-like hydroperoxide resistance protein2 (jann_2040) from jannaschia sp. ccs1 at 1.70 a resolution
49d1p6oa_



not modelled 6.1 11 Fold:Cytidine deaminase-like
Superfamily:Cytidine deaminase-like
Family:Deoxycytidylate deaminase-like
50d1iapa_



not modelled 6.0 13 Fold:Regulator of G-protein signaling, RGS
Superfamily:Regulator of G-protein signaling, RGS
Family:Regulator of G-protein signaling, RGS
51c3lm3A_



not modelled 5.9 28 PDB header:unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a putative glycoside hydrolase/deacetylase2 (bdi_3119) from parabacteroides distasonis at 1.44 a resolution
52d1uspa_



not modelled 5.8 18 Fold:OsmC-like
Superfamily:OsmC-like
Family:Ohr/OsmC resistance proteins
53d2a6aa1



not modelled 5.8 18 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:YeaZ-like
54c2nx8A_



not modelled 5.8 26 PDB header:hydrolase
Chain: A: PDB Molecule:trna-specific adenosine deaminase;
PDBTitle: the crystal structure of the trna-specific adenosine deaminase from2 streptococcus pyogenes
55d2po6a2



not modelled 5.4 15 Fold:MHC antigen-recognition domain
Superfamily:MHC antigen-recognition domain
Family:MHC antigen-recognition domain
56d1onqa2



not modelled 5.3 15 Fold:MHC antigen-recognition domain
Superfamily:MHC antigen-recognition domain
Family:MHC antigen-recognition domain
57c2x58B_



not modelled 5.2 42 PDB header:oxidoreductase
Chain: B: PDB Molecule:peroxisomal bifunctional enzyme;
PDBTitle: the crystal structure of mfe1 liganded with coa

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0