Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP20966
DateThu Jan 5 11:37:49 GMT 2012
Unique Job IDa9b06caa81121719

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d2r48a1
Top template information
Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:PTS system IIB component-like
Family:PTS system, Fructose specific IIB subunit-like
Confidence and coverage
Confidence:100.0% Coverage: 18%
103 residues ( 18% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
446 residues ( 79%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKTLLIIDANLGQARAYMAKTLLGAAARKAKLEIIDNPNDAEMAIVLGDSIPNDSALNGK
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Disorder  ??



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??????
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????


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   .........70.........80.........90.........100.........110.........120
Sequence  NVWLGDISRAVAHPELFLSEAKGHAKPYTAPVAATAPVAASGPKRVVAVTACPTGVAHTF
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?
?






?????????????????????

















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   .........130.........140.........150.........160.........170.........180
Sequence  MAAEAIETEAKKRGWWVKVETRGSVGAGNAITPEEVAAADLVIVAADIEVDLAKFAGKPM
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?
?????

















???







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   .........190.........200.........210.........220.........230.........240
Sequence  YRTSTGLALKKTAQELDKAVAEATPYEPAGKAQTATTESKKESAGAYRHLLTGVSYMLPM
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??
????????????????????















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   .........250.........260.........270.........280.........290.........300
Sequence  VVAGGLCIALSFAFGIEAFKEPGTLAAALMQIGGGSAFALMVPVLAGYIAFSIADRPGLT
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   .........310.........320.........330.........340.........350.........360
Sequence  PGLIGGMLAVSTGSGFIGGIIAGFLAGYIAKLISTQLKLPQSMEALKPILIIPLISSLVV
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??????











































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   .........370.........380.........390.........400.........410.........420
Sequence  GLAMIYLIGKPVAGILEGLTHWLQTMGTANAVLLGAILGGMMCTDMGGPVNKAAYAFGVG
Secondary structure 








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   .........430.........440.........450.........460.........470.........480
Sequence  LLSTQTYGPMAAIMAAGMVPPLAMGLATMVARRKFDKAQQEGGKAALVLGLCFISEGAIP
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   .........490.........500.........510.........520.........530.........540
Sequence  FAARDPMRVLPCCIVGGALTGAISMAIGAKLMAPHGGLFVLLIPGAITPVLGYLVAIIAG
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   .........550.........560...
Sequence  TLVAGLAYAFLKRPEVDAVAKAA
Secondary structure 







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Disorder 














????????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2r48 chain A domain 1

3D model

Region: 105 - 207
Aligned: 103
Modelled: 103
Confidence: 100.0%
Identity: 36%
Fold: Phosphotyrosine protein phosphatases I-like
Superfamily: PTS system IIB component-like
Family: PTS system, Fructose specific IIB subunit-like

Phyre2

PDB 2kyr chain A

3D model

Region: 103 - 201
Aligned: 99
Modelled: 99
Confidence: 100.0%
Identity: 34%
PDB header:transferase
Chain: A: PDB Molecule:fructose-like phosphotransferase enzyme iib component 1;
PDBTitle: solution structure of enzyme iib subunit of pts system from2 escherichia coli k12. northeast structural genomics consortium target3 er315/ontario center for structural proteomics target ec0544

Phyre2

PDB 2r4q chain A domain 1

3D model

Region: 105 - 207
Aligned: 101
Modelled: 103
Confidence: 100.0%
Identity: 39%
Fold: Phosphotyrosine protein phosphatases I-like
Superfamily: PTS system IIB component-like
Family: PTS system, Fructose specific IIB subunit-like

Phyre2

PDB 3qnq chain D

3D model

Region: 219 - 561
Aligned: 341
Modelled: 343
Confidence: 100.0%
Identity: 14%
PDB header:membrane protein, transport protein
Chain: D: PDB Molecule:pts system, cellobiose-specific iic component;
PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system

Phyre2

PDB 1tvm chain A

3D model

Region: 95 - 201
Aligned: 98
Modelled: 107
Confidence: 96.6%
Identity: 20%
PDB header:transferase
Chain: A: PDB Molecule:pts system, galactitol-specific iib component;
PDBTitle: nmr structure of enzyme gatb of the galactitol-specific2 phosphoenolpyruvate-dependent phosphotransferase system

Phyre2

PDB 2a5l chain A domain 1

3D model

Region: 104 - 166
Aligned: 61
Modelled: 63
Confidence: 96.5%
Identity: 16%
Fold: Flavodoxin-like
Superfamily: Flavoproteins
Family: WrbA-like

Phyre2

PDB 1vkr chain A

3D model

Region: 101 - 205
Aligned: 96
Modelled: 105
Confidence: 95.9%
Identity: 18%
PDB header:transferase
Chain: A: PDB Molecule:mannitol-specific pts system enzyme iiabc components;
PDBTitle: structure of iib domain of the mannitol-specific permease enzyme ii

Phyre2

PDB 1vkr chain A

3D model

Region: 101 - 205
Aligned: 96
Modelled: 105
Confidence: 95.9%
Identity: 18%
Fold: Phosphotyrosine protein phosphatases I-like
Superfamily: PTS system IIB component-like
Family: PTS system, Lactose/Cellobiose specific IIB subunit

Phyre2

PDB 1iib chain A

3D model

Region: 112 - 201
Aligned: 84
Modelled: 90
Confidence: 95.6%
Identity: 23%
Fold: Phosphotyrosine protein phosphatases I-like
Superfamily: PTS system IIB component-like
Family: PTS system, Lactose/Cellobiose specific IIB subunit

Phyre2

PDB 3nbm chain A

3D model

Region: 104 - 202
Aligned: 93
Modelled: 99
Confidence: 95.0%
Identity: 18%
PDB header:transferase
Chain: A: PDB Molecule:pts system, lactose-specific iibc components;
PDBTitle: the lactose-specific iib component domain structure of the2 phosphoenolpyruvate:carbohydrate phosphotransferase system (pts) from3 streptococcus pneumoniae.

Phyre2

PDB 1ycg chain A domain 1

3D model

Region: 102 - 166
Aligned: 61
Modelled: 65
Confidence: 94.9%
Identity: 20%
Fold: Flavodoxin-like
Superfamily: Flavoproteins
Family: Flavodoxin-related

Phyre2

PDB 2l2q chain A

3D model

Region: 112 - 201
Aligned: 84
Modelled: 90
Confidence: 94.8%
Identity: 20%
PDB header:transferase
Chain: A: PDB Molecule:pts system, cellobiose-specific iib component (cela);
PDBTitle: solution structure of cellobiose-specific phosphotransferase iib2 component protein from borrelia burgdorferi

Phyre2

PDB 3czc chain A

3D model

Region: 109 - 201
Aligned: 85
Modelled: 93
Confidence: 94.8%
Identity: 14%
PDB header:transferase
Chain: A: PDB Molecule:rmpb;
PDBTitle: the crystal structure of a putative pts iib(ptxb) from2 streptococcus mutans

Phyre2

PDB 3fni chain A

3D model

Region: 102 - 228
Aligned: 124
Modelled: 127
Confidence: 94.5%
Identity: 16%
PDB header:oxidoreductase
Chain: A: PDB Molecule:putative diflavin flavoprotein a 3;
PDBTitle: crystal structure of a diflavin flavoprotein a3 (all3895) from nostoc2 sp., northeast structural genomics consortium target nsr431a

Phyre2

PDB 2ark chain A domain 1

3D model

Region: 105 - 166
Aligned: 54
Modelled: 62
Confidence: 94.5%
Identity: 31%
Fold: Flavodoxin-like
Superfamily: Flavoproteins
Family: WrbA-like

Phyre2

PDB 1ydg chain A

3D model

Region: 102 - 166
Aligned: 63
Modelled: 65
Confidence: 94.1%
Identity: 21%
Fold: Flavodoxin-like
Superfamily: Flavoproteins
Family: WrbA-like

Phyre2

PDB 1vme chain A domain 1

3D model

Region: 102 - 166
Aligned: 63
Modelled: 65
Confidence: 91.9%
Identity: 10%
Fold: Flavodoxin-like
Superfamily: Flavoproteins
Family: Flavodoxin-related

Phyre2

PDB 3p0r chain A

3D model

Region: 105 - 166
Aligned: 61
Modelled: 62
Confidence: 89.5%
Identity: 20%
PDB header:oxidoreductase
Chain: A: PDB Molecule:azoreductase;
PDBTitle: crystal structure of azoreductase from bacillus anthracis str. sterne

Phyre2

PDB 1u7g chain A

3D model

Region: 238 - 363
Aligned: 126
Modelled: 126
Confidence: 89.2%
Identity: 19%
Fold: Ammonium transporter
Superfamily: Ammonium transporter
Family: Ammonium transporter

Phyre2

PDB 1e5d chain A domain 1

3D model

Region: 103 - 228
Aligned: 122
Modelled: 126
Confidence: 86.9%
Identity: 14%
Fold: Flavodoxin-like
Superfamily: Flavoproteins
Family: Flavodoxin-related

Phyre2

PDB 2a0j chain A

3D model

Region: 2 - 48
Aligned: 47
Modelled: 47
Confidence: 79.5%
Identity: 15%
PDB header:transferase
Chain: A: PDB Molecule:pts system, nitrogen regulatory iia protein;
PDBTitle: crystal structure of nitrogen regulatory protein iia-ntr from2 neisseria meningitidis

Phyre2

PDB 3urr chain B

3D model

Region: 2 - 50
Aligned: 49
Modelled: 49
Confidence: 79.2%
Identity: 10%
PDB header:transferase
Chain: B: PDB Molecule:pts iia-like nitrogen-regulatory protein ptsn;
PDBTitle: structure of pts iia-like nitrogen-regulatory protein ptsn (bth_i0484)2 (ptsn)

Phyre2

PDB 1a6j chain A

3D model

Region: 2 - 51
Aligned: 50
Modelled: 50
Confidence: 78.5%
Identity: 10%
Fold: Phoshotransferase/anion transport protein
Superfamily: Phoshotransferase/anion transport protein
Family: IIA domain of mannitol-specific and ntr phosphotransferase EII

Phyre2

PDB 2q62 chain A

3D model

Region: 80 - 166
Aligned: 87
Modelled: 87
Confidence: 74.5%
Identity: 15%
PDB header:flavoprotein
Chain: A: PDB Molecule:arsh;
PDBTitle: crystal structure of arsh from sinorhizobium meliloti

Phyre2

PDB 3d7n chain A

3D model

Region: 2 - 159
Aligned: 140
Modelled: 136
Confidence: 55.4%
Identity: 14%
PDB header:electron transport
Chain: A: PDB Molecule:flavodoxin, wrba-like protein;
PDBTitle: the crystal structure of the flavodoxin, wrba-like protein from2 agrobacterium tumefaciens

Phyre2
1

d2r48a1
2

c2kyrA_
3

d2r4qa1
4

c3qnqD_
5

c1tvmA_
6

d2a5la1
7

c1vkrA_
8

d1vkra_
9

d1iiba_
10

c3nbmA_
11

d1ycga1
12

c2l2qA_
13

c3czcA_
14

c3fniA_
15

d2arka1
16

d1ydga_
17

d1vmea1
18

c3p0rA_
19

d1u7ga_
20

d1e5da1
21



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24



25

c2a0jA_
26

c3urrB_
27



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d1a6ja_
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c2q62A_
35



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c3d7nA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d2r48a1



100.0 36 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:PTS system IIB component-like
Family:PTS system, Fructose specific IIB subunit-like
2c2kyrA_



100.0 34 PDB header:transferase
Chain: A: PDB Molecule:fructose-like phosphotransferase enzyme iib component 1;
PDBTitle: solution structure of enzyme iib subunit of pts system from2 escherichia coli k12. northeast structural genomics consortium target3 er315/ontario center for structural proteomics target ec0544
3d2r4qa1



100.0 39 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:PTS system IIB component-like
Family:PTS system, Fructose specific IIB subunit-like
4c3qnqD_



100.0 14 PDB header:membrane protein, transport protein
Chain: D: PDB Molecule:pts system, cellobiose-specific iic component;
PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system
5c1tvmA_



96.6 20 PDB header:transferase
Chain: A: PDB Molecule:pts system, galactitol-specific iib component;
PDBTitle: nmr structure of enzyme gatb of the galactitol-specific2 phosphoenolpyruvate-dependent phosphotransferase system
6d2a5la1



96.5 16 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:WrbA-like
7c1vkrA_



95.9 18 PDB header:transferase
Chain: A: PDB Molecule:mannitol-specific pts system enzyme iiabc components;
PDBTitle: structure of iib domain of the mannitol-specific permease enzyme ii
8d1vkra_



95.9 18 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:PTS system IIB component-like
Family:PTS system, Lactose/Cellobiose specific IIB subunit
9d1iiba_



95.6 23 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:PTS system IIB component-like
Family:PTS system, Lactose/Cellobiose specific IIB subunit
10c3nbmA_



95.0 18 PDB header:transferase
Chain: A: PDB Molecule:pts system, lactose-specific iibc components;
PDBTitle: the lactose-specific iib component domain structure of the2 phosphoenolpyruvate:carbohydrate phosphotransferase system (pts) from3 streptococcus pneumoniae.
11d1ycga1



94.9 20 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
12c2l2qA_



94.8 20 PDB header:transferase
Chain: A: PDB Molecule:pts system, cellobiose-specific iib component (cela);
PDBTitle: solution structure of cellobiose-specific phosphotransferase iib2 component protein from borrelia burgdorferi
13c3czcA_



94.8 14 PDB header:transferase
Chain: A: PDB Molecule:rmpb;
PDBTitle: the crystal structure of a putative pts iib(ptxb) from2 streptococcus mutans
14c3fniA_



94.5 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative diflavin flavoprotein a 3;
PDBTitle: crystal structure of a diflavin flavoprotein a3 (all3895) from nostoc2 sp., northeast structural genomics consortium target nsr431a
15d2arka1



94.5 31 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:WrbA-like
16d1ydga_



94.1 21 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:WrbA-like
17d1vmea1



91.9 10 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
18c3p0rA_



89.5 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:azoreductase;
PDBTitle: crystal structure of azoreductase from bacillus anthracis str. sterne
19d1u7ga_



89.2 19 Fold:Ammonium transporter
Superfamily:Ammonium transporter
Family:Ammonium transporter
20d1e5da1



86.9 14 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
21d1sqsa_



not modelled 85.6 13 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Hypothetical protein SP1951
22c3snoA_



not modelled 84.3 20 PDB header:transferase
Chain: A: PDB Molecule:hypothetical aminotransferase;
PDBTitle: crystal structure of a hypothetical aminotransferase (ncgl2491) from2 corynebacterium glutamicum atcc 13032 kitasato at 1.60 a resolution
23c2zkiH_



not modelled 82.8 18 PDB header:transcription
Chain: H: PDB Molecule:199aa long hypothetical trp repressor binding
PDBTitle: crystal structure of hypothetical trp repressor binding2 protein from sul folobus tokodaii (st0872)
24c3b6iB_



not modelled 82.8 27 PDB header:flavoprotein
Chain: B: PDB Molecule:flavoprotein wrba;
PDBTitle: wrba from escherichia coli, native structure
25c2a0jA_



79.5 15 PDB header:transferase
Chain: A: PDB Molecule:pts system, nitrogen regulatory iia protein;
PDBTitle: crystal structure of nitrogen regulatory protein iia-ntr from2 neisseria meningitidis
26c3urrB_



79.2 10 PDB header:transferase
Chain: B: PDB Molecule:pts iia-like nitrogen-regulatory protein ptsn;
PDBTitle: structure of pts iia-like nitrogen-regulatory protein ptsn (bth_i0484)2 (ptsn)
27d2qwxa1



not modelled 78.7 29 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Quinone reductase
28d1a6ja_



78.5 10 Fold:Phoshotransferase/anion transport protein
Superfamily:Phoshotransferase/anion transport protein
Family:IIA domain of mannitol-specific and ntr phosphotransferase EII
29c1vmeB_



not modelled 77.5 9 PDB header:electron transport
Chain: B: PDB Molecule:flavoprotein;
PDBTitle: crystal structure of flavoprotein (tm0755) from thermotoga maritima at2 1.80 a resolution
30c2ohiB_



not modelled 77.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:type a flavoprotein fpra;
PDBTitle: crystal structure of coenzyme f420h2 oxidase (fpra), a diiron2 flavoprotein, reduced state
31c1ychD_



not modelled 75.5 14 PDB header:oxidoreductase
Chain: D: PDB Molecule:nitric oxide reductase;
PDBTitle: x-ray crystal structures of moorella thermoacetica fpra.2 novel diiron site structure and mechanistic insights into3 a scavenging nitric oxide reductase
32c3f2vA_



not modelled 75.0 11 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:general stress protein 14;
PDBTitle: crystal structure of the general stress protein 142 (tde0354) in complex with fmn from treponema denticola,3 northeast structural genomics consortium target tdr58.
33c3rh0A_



not modelled 74.5 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:arsenate reductase;
PDBTitle: corynebacterium glutamicum mycothiol/mycoredoxin1-dependent arsenate2 reductase cg_arsc2
34c2q62A_



74.5 15 PDB header:flavoprotein
Chain: A: PDB Molecule:arsh;
PDBTitle: crystal structure of arsh from sinorhizobium meliloti
35c3oxpA_



not modelled 73.2 10 PDB header:transferase
Chain: A: PDB Molecule:phosphotransferase enzyme ii, a component;
PDBTitle: structure of phosphotransferase enzyme ii, a component from yersinia2 pestis co92 at 1.2 a resolution
36c3oxpB_



not modelled 73.2 10 PDB header:transferase
Chain: B: PDB Molecule:phosphotransferase enzyme ii, a component;
PDBTitle: structure of phosphotransferase enzyme ii, a component from yersinia2 pestis co92 at 1.2 a resolution
37c3klbA_



not modelled 71.9 16 PDB header:flavoprotein
Chain: A: PDB Molecule:putative flavoprotein;
PDBTitle: crystal structure of putative flavoprotein in complex with fmn2 (yp_213683.1) from bacteroides fragilis nctc 9343 at 1.75 a3 resolution
38c2oq3A_



not modelled 70.9 12 PDB header:transferase
Chain: A: PDB Molecule:mannitol-specific cryptic phosphotransferase
PDBTitle: solution structure of the mannitol- specific cryptic2 phosphotransferase enzyme iia cmtb from escherichia coli
39d1t0ba_



not modelled 68.7 18 Fold:Flavodoxin-like
Superfamily:Class I glutamine amidotransferase-like
Family:ThuA-like
40c3h9gA_



not modelled 68.0 24 PDB header:transferase/antibiotic
Chain: A: PDB Molecule:mccb protein;
PDBTitle: crystal structure of e. coli mccb + mcca-n7isoasn
41c3fvwA_



not modelled 65.9 23 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative nad(p)h-dependent fmn reductase;
PDBTitle: crystal structure of the q8dwd8_strmu protein from2 streptococcus mutans. northeast structural genomics3 consortium target smr99.
42c2oqtD_



not modelled 65.6 7 PDB header:transferase
Chain: D: PDB Molecule:hypothetical protein spy0176;
PDBTitle: structural genomics, the crystal structure of a putative2 pts iia domain from streptococcus pyogenes m1 gas
43c3edoA_



not modelled 65.5 18 PDB header:flavoprotein
Chain: A: PDB Molecule:putative trp repressor binding protein;
PDBTitle: crystal structure of flavoprotein in complex with fmn2 (yp_193882.1) from lactobacillus acidophilus ncfm at 1.203 a resolution
44d1qrda_



not modelled 65.5 35 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Quinone reductase
45d1j4na_



not modelled 64.0 14 Fold:Aquaporin-like
Superfamily:Aquaporin-like
Family:Aquaporin-like
46c1zggA_



not modelled 61.7 29 PDB header:hydrolase
Chain: A: PDB Molecule:putative low molecular weight protein-tyrosine-
PDBTitle: solution structure of a low molecular weight protein2 tyrosine phosphatase from bacillus subtilis
47c2v9cA_



not modelled 59.2 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:fmn-dependent nadh-azoreductase 1;
PDBTitle: x-ray crystallographic structure of a pseudomonas2 aeruginosa azoreductase in complex with methyl red.
48c3c1iA_



not modelled 56.3 20 PDB header:transport protein
Chain: A: PDB Molecule:ammonia channel;
PDBTitle: substrate binding, deprotonation and selectivity at the2 periplasmic entrance of the e. coli ammonia channel amtb
49c3hd6A_



not modelled 56.1 16 PDB header:membrane protein, transport protein
Chain: A: PDB Molecule:ammonium transporter rh type c;
PDBTitle: crystal structure of the human rhesus glycoprotein rhcg
50c3k9cA_



not modelled 55.9 17 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, laci family protein;
PDBTitle: crystal structure of laci transcriptional regulator from rhodococcus2 species.
51c3d7nA_



55.4 14 PDB header:electron transport
Chain: A: PDB Molecule:flavodoxin, wrba-like protein;
PDBTitle: the crystal structure of the flavodoxin, wrba-like protein from2 agrobacterium tumefaciens
52d1gtza_



not modelled 54.9 15 Fold:Flavodoxin-like
Superfamily:Type II 3-dehydroquinate dehydratase
Family:Type II 3-dehydroquinate dehydratase
53c3bjvA_



not modelled 54.7 14 PDB header:transferase
Chain: A: PDB Molecule:rmpa;
PDBTitle: the crystal structure of a putative pts iia(ptxa) from streptococcus2 mutans
54c2b2hA_



not modelled 53.6 23 PDB header:transport protein
Chain: A: PDB Molecule:ammonium transporter;
PDBTitle: ammonium transporter amt-1 from a. fulgidus (as)
55c3hlyA_



not modelled 53.5 10 PDB header:flavoprotein
Chain: A: PDB Molecule:flavodoxin-like domain;
PDBTitle: crystal structure of the flavodoxin-like domain from2 synechococcus sp q5mzp6_synp6 protein. northeast structural3 genomics consortium target snr135d.
56c2vzhA_



not modelled 53.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadh-dependent fmn reductase;
PDBTitle: structures of nadh:fmn oxidoreductase (emob)-fmn complex
57c1wrvB_



not modelled 52.7 22 PDB header:transferase
Chain: B: PDB Molecule:branched-chain amino acid aminotransferase;
PDBTitle: crystal structure of t.th.hb8 branched-chain amino acid2 aminotransferase
58d1t5ba_



not modelled 52.6 15 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Quinone reductase
59d2fzva1



not modelled 52.2 9 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:NADPH-dependent FMN reductase
60c2q9uB_



not modelled 51.1 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:a-type flavoprotein;
PDBTitle: crystal structure of the flavodiiron protein from giardia2 intestinalis
61d1acoa2



not modelled 50.8 19 Fold:Aconitase iron-sulfur domain
Superfamily:Aconitase iron-sulfur domain
Family:Aconitase iron-sulfur domain
62c2ad5B_



not modelled 49.6 18 PDB header:ligase
Chain: B: PDB Molecule:ctp synthase;
PDBTitle: mechanisms of feedback regulation and drug resistance of ctp2 synthetases: structure of the e. coli ctps/ctp complex at 2.8-3 angstrom resolution.
63d1pvva2



not modelled 49.5 19 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
64d1jw9b_



not modelled 49.4 15 Fold:Activating enzymes of the ubiquitin-like proteins
Superfamily:Activating enzymes of the ubiquitin-like proteins
Family:Molybdenum cofactor biosynthesis protein MoeB
65c3rpeA_



not modelled 48.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:modulator of drug activity b;
PDBTitle: 1.1 angstrom crystal structure of putative modulator of drug activity2 (mdab) from yersinia pestis co92.
66d1a3xa2



not modelled 47.6 32 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:Pyruvate kinase
67d1rtta_



not modelled 45.5 18 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:NADPH-dependent FMN reductase
68d5nula_



not modelled 44.8 23 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
69c2l18A_



not modelled 44.0 10 PDB header:oxidoreductase
Chain: A: PDB Molecule:arsenate reductase;
PDBTitle: an arsenate reductase in the phosphate binding state
70c3chgB_



not modelled 43.6 24 PDB header:ligand binding protein
Chain: B: PDB Molecule:glycine betaine-binding protein;
PDBTitle: the compatible solute-binding protein opuac from bacillus2 subtilis in complex with dmsa
71d1h05a_



not modelled 43.4 22 Fold:Flavodoxin-like
Superfamily:Type II 3-dehydroquinate dehydratase
Family:Type II 3-dehydroquinate dehydratase
72c2fzvC_



not modelled 43.3 10 PDB header:structural genomics, unknown function
Chain: C: PDB Molecule:putative arsenical resistance protein;
PDBTitle: crystal structure of an apo form of a flavin-binding protein from2 shigella flexneri
73d2b3ya2



not modelled 43.2 24 Fold:Aconitase iron-sulfur domain
Superfamily:Aconitase iron-sulfur domain
Family:Aconitase iron-sulfur domain
74d1pkla2



not modelled 42.8 25 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:Pyruvate kinase
75c3cswB_



not modelled 42.4 16 PDB header:transferase
Chain: B: PDB Molecule:putative branched-chain-amino-acid aminotransferase;
PDBTitle: crystal structure of a putative branched-chain amino acid2 aminotransferase (tm0831) from thermotoga maritima at 2.15 a3 resolution
76c3lcmB_



not modelled 42.3 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of smu.1420 from streptococcus mutans ua159
77c1a3wB_



not modelled 41.8 31 PDB header:transferase
Chain: B: PDB Molecule:pyruvate kinase;
PDBTitle: pyruvate kinase from saccharomyces cerevisiae complexed with fbp, pg,2 mn2+ and k+
78c3kydB_



not modelled 41.6 16 PDB header:ligase
Chain: B: PDB Molecule:sumo-activating enzyme subunit 2;
PDBTitle: human sumo e1~sumo1-amp tetrahedral intermediate mimic
79c2hpvA_



not modelled 41.5 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:fmn-dependent nadh-azoreductase;
PDBTitle: crystal structure of fmn-dependent azoreductase from enterococcus2 faecalis
80c5acnA_



not modelled 41.3 19 PDB header:lyase(carbon-oxygen)
Chain: A: PDB Molecule:aconitase;
PDBTitle: structure of activated aconitase. formation of the (4fe-4s)2 cluster in the crystal
81c2gi4A_



not modelled 40.6 25 PDB header:hydrolase
Chain: A: PDB Molecule:possible phosphotyrosine protein phosphatase;
PDBTitle: solution structure of the low molecular weight protein2 tyrosine phosphatase from campylobacter jejuni.
82d2gk3a1



not modelled 40.5 14 Fold:Flavodoxin-like
Superfamily:Class I glutamine amidotransferase-like
Family:STM3548-like
83c1y8qD_



not modelled 40.3 16 PDB header:ligase
Chain: D: PDB Molecule:ubiquitin-like 2 activating enzyme e1b;
PDBTitle: sumo e1 activating enzyme sae1-sae2-mg-atp complex
84c3djeA_



not modelled 39.6 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:fructosyl amine: oxygen oxidoreductase;
PDBTitle: crystal structure of the deglycating enzyme fructosamine2 oxidase from aspergillus fumigatus (amadoriase ii) in3 complex with fsa
85d1ekxa2



not modelled 39.3 17 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
86c3khdC_



not modelled 38.6 16 PDB header:transferase
Chain: C: PDB Molecule:pyruvate kinase;
PDBTitle: crystal structure of pff1300w.
87d1bala_



not modelled 38.3 21 Fold:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
Superfamily:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
Family:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
88d1gqoa_



not modelled 37.3 8 Fold:Flavodoxin-like
Superfamily:Type II 3-dehydroquinate dehydratase
Family:Type II 3-dehydroquinate dehydratase
89c2hqbA_



not modelled 37.2 18 PDB header:transcription
Chain: A: PDB Molecule:transcriptional activator of comk gene;
PDBTitle: crystal structure of a transcriptional activator of comk2 gene from bacillus halodurans
90d1jf8a_



not modelled 37.1 12 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:Phosphotyrosine protein phosphatases I
Family:Low-molecular-weight phosphotyrosine protein phosphatases
91d1liua2



not modelled 36.9 27 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:Pyruvate kinase
92c2rjoA_



not modelled 36.7 17 PDB header:signaling protein
Chain: A: PDB Molecule:twin-arginine translocation pathway signal protein;
PDBTitle: crystal structure of twin-arginine translocation pathway signal2 protein from burkholderia phytofirmans
93c2an1D_



not modelled 36.4 27 PDB header:transferase
Chain: D: PDB Molecule:putative kinase;
PDBTitle: structural genomics, the crystal structure of a putative kinase from2 salmonella typhimurim lt2
94c3d02A_



not modelled 36.3 10 PDB header:sugar binding protein
Chain: A: PDB Molecule:putative laci-type transcriptional regulator;
PDBTitle: crystal structure of periplasmic sugar-binding protein2 (yp_001338366.1) from klebsiella pneumoniae subsp. pneumoniae mgh3 78578 at 1.30 a resolution
95c2eq8C_



not modelled 35.7 27 PDB header:oxidoreductase
Chain: C: PDB Molecule:pyruvate dehydrogenase complex, dihydrolipoamide
PDBTitle: crystal structure of lipoamide dehydrogenase from thermus thermophilus2 hb8 with psbdp
96c1zfnA_



not modelled 34.8 15 PDB header:transferase
Chain: A: PDB Molecule:adenylyltransferase thif;
PDBTitle: structural analysis of escherichia coli thif
97c3n8kG_



not modelled 34.8 21 PDB header:lyase
Chain: G: PDB Molecule:3-dehydroquinate dehydratase;
PDBTitle: type ii dehydroquinase from mycobacterium tuberculosis complexed with2 citrazinic acid
98d1dxqa_



not modelled 34.5 34 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Quinone reductase
99c1t5aB_



not modelled 34.4 26 PDB header:transferase
Chain: B: PDB Molecule:pyruvate kinase, m2 isozyme;
PDBTitle: human pyruvate kinase m2
100c3k1yE_



not modelled 33.5 19 PDB header:oxidoreductase
Chain: E: PDB Molecule:oxidoreductase;
PDBTitle: x-ray structure of oxidoreductase from corynebacterium2 diphtheriae. orthorombic crystal form, northeast structural3 genomics consortium target cdr100d
101d1c0aa2



not modelled 33.4 29 Fold:DCoH-like
Superfamily:GAD domain-like
Family:GAD domain
102d1iyea_



not modelled 33.2 23 Fold:D-aminoacid aminotransferase-like PLP-dependent enzymes
Superfamily:D-aminoacid aminotransferase-like PLP-dependent enzymes
Family:D-aminoacid aminotransferase-like PLP-dependent enzymes
103c3ma8A_



not modelled 33.0 24 PDB header:transferase
Chain: A: PDB Molecule:pyruvate kinase;
PDBTitle: crystal structure of cgd1_2040, a pyruvate kinase from cryptosporidium2 parvum
104c3jviA_



not modelled 33.0 8 PDB header:hydrolase
Chain: A: PDB Molecule:protein tyrosine phosphatase;
PDBTitle: product state mimic crystal structure of protein tyrosine phosphatase2 from entamoeba histolytica
105c3lwzC_



not modelled 32.7 10 PDB header:lyase
Chain: C: PDB Molecule:3-dehydroquinate dehydratase;
PDBTitle: 1.65 angstrom resolution crystal structure of type ii 3-2 dehydroquinate dehydratase (aroq) from yersinia pestis
106c3o1hB_



not modelled 32.7 15 PDB header:signaling protein
Chain: B: PDB Molecule:periplasmic protein tort;
PDBTitle: crystal structure of the tors sensor domain - tort complex in the2 presence of tmao
107d1xiza_



not modelled 32.1 6 Fold:Phoshotransferase/anion transport protein
Superfamily:Phoshotransferase/anion transport protein
Family:IIA domain of mannitol-specific and ntr phosphotransferase EII
108c1e5dA_



not modelled 32.0 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:rubredoxin\:oxygen oxidoreductase;
PDBTitle: rubredoxin oxygen:oxidoreductase (roo) from anaerobe2 desulfovibrio gigas
109c1pklB_



not modelled 31.2 24 PDB header:transferase
Chain: B: PDB Molecule:protein (pyruvate kinase);
PDBTitle: the structure of leishmania pyruvate kinase
110d1q6za1



not modelled 30.1 15 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
111d2bcgg1



not modelled 30.1 18 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:GDI-like N domain
112d2g50a2



not modelled 30.0 27 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:Pyruvate kinase
113c2wdpA_



not modelled 29.9 17 PDB header:hydrolase
Chain: A: PDB Molecule:caspase-6;
PDBTitle: crystal structure of ligand free human caspase-6
114d1oboa_



not modelled 29.1 17 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
115c2eq9C_



not modelled 28.8 24 PDB header:oxidoreductase
Chain: C: PDB Molecule:pyruvate dehydrogenase complex, dihydrolipoamide
PDBTitle: crystal structure of lipoamide dehydrogenase from thermus thermophilus2 hb8 with psbdb
116c2qgzA_



not modelled 28.5 15 PDB header:hydrolase
Chain: A: PDB Molecule:putative primosome component;
PDBTitle: crystal structure of a putative primosome component from2 streptococcus pyogenes serotype m3. northeast structural3 genomics target dr58
117c3l49D_



not modelled 28.3 15 PDB header:transport protein
Chain: D: PDB Molecule:abc sugar (ribose) transporter, periplasmic
PDBTitle: crystal structure of abc sugar transporter subunit from2 rhodobacter sphaeroides 2.4.1
118c3fmfA_



not modelled 28.0 21 PDB header:ligase
Chain: A: PDB Molecule:dethiobiotin synthetase;
PDBTitle: crystal structure of mycobacterium tuberculosis dethiobiotin2 synthetase complexed with 7,8 diaminopelargonic acid carbamate
119c2b3yB_



not modelled 27.6 22 PDB header:lyase
Chain: B: PDB Molecule:iron-responsive element binding protein 1;
PDBTitle: structure of a monoclinic crystal form of human cytosolic aconitase2 (irp1)
120d1duvg1



not modelled 27.5 19 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0