PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2wdpA_

Fold library id	PDB Header	Molecule	Title
c2wdpA_	PDB header: hydrolase	Chain: A: PDB Molecule: caspase-6;	PDBTitle: crystal structure of ligand free human caspase-6

Links to external resources
Added to library: Sat Aug 28 21:12:46 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence F D P A E K Y K M D H R R R G I A L I F N H E R F F W H L T L P E R R G T C A D R D N L T R R F S D L G F E V K C F N D L K A E E L L L K I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
B
S S B
T T
T T
S S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence H E V S T V S H A D A D C F V C V F L S H G E G N H I Y A Y D A K I E I Q T L T G L F K G D K C H S L V G K P K I F I I Q A C R G L P A G A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T B S
S B
T S T T T
G G G T T S
B
T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence D F L M C Y S V A E G Y Y S H R E T V N G S W Y I Q D L C E M L G K Y G S S L E F T E L L T L V N R K V S Q R R V P S A I G K K Q V P C F A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S S S S S S
B T T B
T T T S
S
S

. . . . . . . . . 220 . . . .

Sequence S M L T K K L H F F P K S N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S B

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	F	D	P	A	E	K	Y	K	M	D	H	R	R	R	G	I	A	L	I	F	N	H	E	R	F	F	W	H	L	T	L	P	E	R	R	G	T	C	A	D	R	D	N	L	T	R	R	F	S	D	L	G	F	E	V	K	C	F	N	D	L	K	A	E	E	L	L	L	K	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T		B					S	S	B											T	T																										T	T								S	S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	H	E	V	S	T	V	S	H	A	D	A	D	C	F	V	C	V	F	L	S	H	G	E	G	N	H	I	Y	A	Y	D	A	K	I	E	I	Q	T	L	T	G	L	F	K	G	D	K	C	H	S	L	V	G	K	P	K	I	F	I	I	Q	A	C	R	G	L	P	A	G	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S				T	T	B	S										S	B																				T	S	T	T	T		G	G	G	T	T	S										B						T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	D	F	L	M	C	Y	S	V	A	E	G	Y	Y	S	H	R	E	T	V	N	G	S	W	Y	I	Q	D	L	C	E	M	L	G	K	Y	G	S	S	L	E	F	T	E	L	L	T	L	V	N	R	K	V	S	Q	R	R	V	P	S	A	I	G	K	K	Q	V	P	C	F	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T						S	S	S	S	S	S						B	T	T	B															T	T	T	S																					S			S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.
Sequence	S	M	L	T	K	K	L	H	F	F	P	K	S	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S	B