Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	H	P	A	L	T	Q	L	R	A	L	R	Y	C	K	E	I	P	A	L	D	P	Q	L	L	D	W	L	L	L	E	D	S	M	T	K	R	F	E	Q	Q	G	K	T	V	S	V	T	M	I	R	E	G	F	V	E	Q	N	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?				?	?	?		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	P	E	E	L	P	L	L	P	K	E	S	R	Y	W	L	R	E	I	L	L	C	A	D	G	E	P	W	L	A	G	R	T	V	V	P	V	S	T	L	S	G	P	E	L	A	L	Q	K	L	G	K	T	P	L	G	R	Y	L	F
Secondary structure
SS confidence
Disorder																																																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.
Sequence		T	S	S	T	L	T	R	D	F	I	E	I	G	R	D	A	G	L	W	G	R	R	S	R	L	R	L	S	G	K	P	L	L	L	T	E	L	F	L	P	A	S	P	L	Y
Secondary structure
SS confidence
Disorder																																											?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1tt8 chain A Region: 2 - 165 Aligned: 164 Modelled: 164 Confidence: 100.0% Identity: 99% Fold: Chorismate lyase-like Superfamily: Chorismate lyase-like Family: Chorismate lyase Phyre2 PDB 2nwi chain A domain 1 Region: 21 - 161 Aligned: 141 Modelled: 141 Confidence: 100.0% Identity: 21% Fold: Chorismate lyase-like Superfamily: Chorismate lyase-like Family: AF1396-like Phyre2 PDB 3f8l chain C Region: 29 - 161 Aligned: 131 Modelled: 133 Confidence: 98.4% Identity: 16% PDB header:transcription Chain: C: PDB Molecule:hth-type transcriptional repressor phnf; PDBTitle: crystal structure of the effector domain of phnf from mycobacterium2 smegmatis Phyre2 PDB 3hfi chain A Region: 47 - 161 Aligned: 113 Modelled: 115 Confidence: 97.8% Identity: 12% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative regulator; PDBTitle: the crystal structure of the putative regulator from escherichia coli2 cft073 Phyre2 PDB 3cnv chain A domain 1 Region: 39 - 161 Aligned: 123 Modelled: 123 Confidence: 97.8% Identity: 11% Fold: Chorismate lyase-like Superfamily: Chorismate lyase-like Family: UTRA domain Phyre2 PDB 2pkh chain A domain 1 Region: 45 - 161 Aligned: 115 Modelled: 117 Confidence: 97.6% Identity: 12% Fold: Chorismate lyase-like Superfamily: Chorismate lyase-like Family: UTRA domain Phyre2 PDB 2fa1 chain A domain 1 Region: 29 - 161 Aligned: 130 Modelled: 133 Confidence: 97.6% Identity: 13% Fold: Chorismate lyase-like Superfamily: Chorismate lyase-like Family: UTRA domain Phyre2 PDB 2p19 chain A domain 1 Region: 40 - 161 Aligned: 119 Modelled: 122 Confidence: 97.4% Identity: 17% Fold: Chorismate lyase-like Superfamily: Chorismate lyase-like Family: UTRA domain Phyre2 PDB 2ikk chain A domain 1 Region: 45 - 161 Aligned: 115 Modelled: 114 Confidence: 97.4% Identity: 12% Fold: Chorismate lyase-like Superfamily: Chorismate lyase-like Family: UTRA domain Phyre2 PDB 2ogg chain A domain 1 Region: 49 - 161 Aligned: 110 Modelled: 113 Confidence: 97.2% Identity: 15% Fold: Chorismate lyase-like Superfamily: Chorismate lyase-like Family: UTRA domain Phyre2 PDB 2ra5 chain A domain 1 Region: 41 - 161 Aligned: 118 Modelled: 121 Confidence: 97.0% Identity: 18% Fold: Chorismate lyase-like Superfamily: Chorismate lyase-like Family: UTRA domain Phyre2 PDB 2ra5 chain A Region: 41 - 161 Aligned: 118 Modelled: 121 Confidence: 97.0% Identity: 18% PDB header:transcription Chain: A: PDB Molecule:putative transcriptional regulator; PDBTitle: crystal structure of the putative transcriptional regulator2 from streptomyces coelicolor Phyre2 PDB 3bwg chain A domain 2 Region: 45 - 165 Aligned: 118 Modelled: 121 Confidence: 96.9% Identity: 8% Fold: Chorismate lyase-like Superfamily: Chorismate lyase-like Family: UTRA domain Phyre2 PDB 2ooi chain A domain 1 Region: 33 - 158 Aligned: 123 Modelled: 126 Confidence: 96.9% Identity: 11% Fold: Chorismate lyase-like Superfamily: Chorismate lyase-like Family: UTRA domain Phyre2 PDB 3ddv chain A domain 1 Region: 47 - 161 Aligned: 94 Modelled: 94 Confidence: 96.3% Identity: 19% Fold: Chorismate lyase-like Superfamily: Chorismate lyase-like Family: UTRA domain Phyre2 PDB 3lhe chain A Region: 42 - 102 Aligned: 61 Modelled: 61 Confidence: 95.1% Identity: 21% PDB header:transcription regulator Chain: A: PDB Molecule:gntr family transcriptional regulator; PDBTitle: the crystal structure of the c-terminal domain of a gntr2 family transcriptional regulator from bacillus anthracis3 str. sterne Phyre2 PDB 3f8m chain A Region: 30 - 161 Aligned: 130 Modelled: 132 Confidence: 84.3% Identity: 16% PDB header:transcription Chain: A: PDB Molecule:gntr-family protein transcriptional regulator; PDBTitle: crystal structure of phnf from mycobacterium smegmatis Phyre2 PDB 3eet chain A Region: 31 - 161 Aligned: 131 Modelled: 131 Confidence: 80.9% Identity: 11% PDB header:transcription regulator Chain: A: PDB Molecule:putative gntr-family transcriptional regulator; PDBTitle: crystal structure of putative gntr-family transcriptional2 regulator Phyre2 PDB 3edp chain B Region: 36 - 161 Aligned: 123 Modelled: 126 Confidence: 57.7% Identity: 9% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:lin2111 protein; PDBTitle: the crystal structure of the protein lin2111 (functionally unknown)2 from listeria innocua clip11262 Phyre2 PDB 2wv0 chain H Region: 32 - 101 Aligned: 70 Modelled: 70 Confidence: 35.7% Identity: 10% PDB header:transcription Chain: H: PDB Molecule:hth-type transcriptional repressor yvoa; PDBTitle: crystal structure of the gntr-hutc family member yvoa from2 bacillus subtilis Phyre2 1 d1tt8a_ 2 d2nwia1 3 c3f8lC_ 4 c3hfiA_ 5 d3cnva1 6 d2pkha1 7 d2fa1a1 8 d2p19a1 9 d2ikka1 10 d2ogga1 11 d2ra5a1 12 c2ra5A_ 13 d3bwga2 14 d2ooia1 15 d3ddva1 16 c3lheA_ 17 c3f8mA_ 18 c3eetA_ 19 c3edpB_ 20 c2wv0H_ 21 22

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1tt8a_ 100.0 99 Fold:Chorismate lyase-like Superfamily:Chorismate lyase-like Family:Chorismate lyase 2 d2nwia1 100.0 21 Fold:Chorismate lyase-like Superfamily:Chorismate lyase-like Family:AF1396-like 3 c3f8lC_ 98.4 16 PDB header:transcription Chain: C: PDB Molecule:hth-type transcriptional repressor phnf; PDBTitle: crystal structure of the effector domain of phnf from mycobacterium2 smegmatis 4 c3hfiA_ 97.8 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative regulator; PDBTitle: the crystal structure of the putative regulator from escherichia coli2 cft073 5 d3cnva1 97.8 11 Fold:Chorismate lyase-like Superfamily:Chorismate lyase-like Family:UTRA domain 6 d2pkha1 97.6 12 Fold:Chorismate lyase-like Superfamily:Chorismate lyase-like Family:UTRA domain 7 d2fa1a1 97.6 13 Fold:Chorismate lyase-like Superfamily:Chorismate lyase-like Family:UTRA domain 8 d2p19a1 97.4 17 Fold:Chorismate lyase-like Superfamily:Chorismate lyase-like Family:UTRA domain 9 d2ikka1 97.4 12 Fold:Chorismate lyase-like Superfamily:Chorismate lyase-like Family:UTRA domain 10 d2ogga1 97.2 15 Fold:Chorismate lyase-like Superfamily:Chorismate lyase-like Family:UTRA domain 11 d2ra5a1 97.0 18 Fold:Chorismate lyase-like Superfamily:Chorismate lyase-like Family:UTRA domain 12 c2ra5A_ 97.0 18 PDB header:transcription Chain: A: PDB Molecule:putative transcriptional regulator; PDBTitle: crystal structure of the putative transcriptional regulator2 from streptomyces coelicolor 13 d3bwga2 96.9 8 Fold:Chorismate lyase-like Superfamily:Chorismate lyase-like Family:UTRA domain 14 d2ooia1 96.9 11 Fold:Chorismate lyase-like Superfamily:Chorismate lyase-like Family:UTRA domain 15 d3ddva1 96.3 19 Fold:Chorismate lyase-like Superfamily:Chorismate lyase-like Family:UTRA domain 16 c3lheA_ 95.1 21 PDB header:transcription regulator Chain: A: PDB Molecule:gntr family transcriptional regulator; PDBTitle: the crystal structure of the c-terminal domain of a gntr2 family transcriptional regulator from bacillus anthracis3 str. sterne 17 c3f8mA_ 84.3 16 PDB header:transcription Chain: A: PDB Molecule:gntr-family protein transcriptional regulator; PDBTitle: crystal structure of phnf from mycobacterium smegmatis 18 c3eetA_ 80.9 11 PDB header:transcription regulator Chain: A: PDB Molecule:putative gntr-family transcriptional regulator; PDBTitle: crystal structure of putative gntr-family transcriptional2 regulator 19 c3edpB_ 57.7 9 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:lin2111 protein; PDBTitle: the crystal structure of the protein lin2111 (functionally unknown)2 from listeria innocua clip11262 20 c2wv0H_ 35.7 10 PDB header:transcription Chain: H: PDB Molecule:hth-type transcriptional repressor yvoa; PDBTitle: crystal structure of the gntr-hutc family member yvoa from2 bacillus subtilis 21 c3bwgA_ not modelled 10.8 8 PDB header:transcription regulator Chain: A: PDB Molecule:uncharacterized hth-type transcriptional regulator yydk; PDBTitle: the crystal structure of possible transcriptional regulator yydk from2 bacillus subtilis subsp. subtilis str. 168 22 d1dsva_ not modelled 9.1 25 Fold:Retrovirus zinc finger-like domains Superfamily:Retrovirus zinc finger-like domains Family:Retrovirus zinc finger-like domains

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0