Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	K	C	L	T	L	L	I	A	T	V	L	S	G	I	S	L	T	A	Y	A	A	Q	P	M	S	N	L	D	S	G	Q	L	R	P	A	G	T	V	S	A	T	G	A	S	N	L	S	D	L	E	D	K	L	A	E	K	A	R
Secondary structure
SS confidence
Disorder		?	?	?	?													?	?			?	?	?	?		?	?	?			?	?	?	?	?		?						?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.
Sequence		E	Q	G	A	K	G	Y	V	I	N	S	A	G	G	N	D	Q	M	F	G	T	A	T	I	Y	K
Secondary structure
SS confidence
Disorder			?	?	?	?										?	?	?									?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2noc chain A domain 1 Region: 1 - 86 Aligned: 85 Modelled: 86 Confidence: 100.0% Identity: 34% Fold: Dodecin subunit-like Superfamily: YdgH-like Family: YdgH-like Phyre2 PDB 2jna chain A domain 1 Region: 1 - 86 Aligned: 85 Modelled: 86 Confidence: 100.0% Identity: 31% Fold: Dodecin subunit-like Superfamily: YdgH-like Family: YdgH-like Phyre2 PDB 2k4q chain A Region: 16 - 84 Aligned: 69 Modelled: 69 Confidence: 54.2% Identity: 12% PDB header:viral protein Chain: A: PDB Molecule:major tail protein v; PDBTitle: the solution structure of gpv, the major tail protein from2 bacteriophage lambda Phyre2 PDB 3dfe chain A Region: 51 - 76 Aligned: 26 Modelled: 26 Confidence: 31.8% Identity: 38% PDB header:signaling protein Chain: A: PDB Molecule:putative pii-like signaling protein; PDBTitle: crystal structure of a putative pii-like signaling protein2 (yp_323533.1) from anabaena variabilis atcc 29413 at 2.35 a3 resolution Phyre2 PDB 3dnf chain B Region: 17 - 61 Aligned: 43 Modelled: 45 Confidence: 26.1% Identity: 16% PDB header:oxidoreductase Chain: B: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate reductase; PDBTitle: structure of (e)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase,2 the terminal enzyme of the non-mevalonate pathway Phyre2 PDB 1kjq chain A domain 1 Region: 28 - 61 Aligned: 33 Modelled: 34 Confidence: 25.7% Identity: 18% Fold: Barrel-sandwich hybrid Superfamily: Rudiment single hybrid motif Family: BC C-terminal domain-like Phyre2 PDB 3ke8 chain A Region: 17 - 64 Aligned: 46 Modelled: 48 Confidence: 22.8% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate PDBTitle: crystal structure of isph:hmbpp-complex Phyre2 PDB 3b9n chain B Region: 46 - 70 Aligned: 25 Modelled: 25 Confidence: 20.6% Identity: 16% PDB header:oxidoreductase Chain: B: PDB Molecule:alkane monoxygenase; PDBTitle: crystal structure of long-chain alkane monooxygenase (lada) Phyre2 PDB 3etj chain A domain 1 Region: 30 - 57 Aligned: 27 Modelled: 28 Confidence: 20.0% Identity: 26% Fold: Barrel-sandwich hybrid Superfamily: Rudiment single hybrid motif Family: BC C-terminal domain-like Phyre2 PDB 2y1b chain A Region: 23 - 71 Aligned: 46 Modelled: 49 Confidence: 20.0% Identity: 17% PDB header:membrane protein Chain: A: PDB Molecule:putative outer membrane protein, signal; PDBTitle: crystal structure of the e. coli outer membrane lipoprotein2 rcsf Phyre2 PDB 1hl8 chain B Region: 53 - 76 Aligned: 24 Modelled: 24 Confidence: 19.4% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:putative alpha-l-fucosidase; PDBTitle: crystal structure of thermotoga maritima alpha-fucosidase Phyre2 PDB 3lub chain E Region: 38 - 76 Aligned: 38 Modelled: 39 Confidence: 19.3% Identity: 13% PDB header:hydrolase Chain: E: PDB Molecule:putative creatinine amidohydrolase; PDBTitle: crystal structure of putative creatinine amidohydrolase2 (yp_211512.1) from bacteroides fragilis nctc 9343 at 2.11 a3 resolution Phyre2 PDB 3no4 chain A Region: 38 - 76 Aligned: 38 Modelled: 39 Confidence: 18.5% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:creatinine amidohydrolase; PDBTitle: crystal structure of a creatinine amidohydrolase (npun_f1913) from2 nostoc punctiforme pcc 73102 at 2.00 a resolution Phyre2 PDB 3eyp chain B Region: 53 - 76 Aligned: 24 Modelled: 24 Confidence: 14.6% Identity: 4% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative alpha-l-fucosidase; PDBTitle: crystal structure of putative alpha-l-fucosidase from bacteroides2 thetaiotaomicron Phyre2 PDB 2v82 chain A Region: 34 - 70 Aligned: 36 Modelled: 37 Confidence: 13.5% Identity: 6% PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase; PDBTitle: kdpgal complexed to kdpgal Phyre2 PDB 3qkb chain B Region: 49 - 65 Aligned: 17 Modelled: 17 Confidence: 13.2% Identity: 24% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a protein with unknown function which belongs to2 pfam duf74 family (pepe_0654) from pediococcus pentosaceus atcc 257453 at 2.73 a resolution Phyre2 PDB 3mo4 chain B Region: 53 - 76 Aligned: 24 Modelled: 24 Confidence: 13.2% Identity: 13% PDB header:hydrolase Chain: B: PDB Molecule:alpha-1,3/4-fucosidase; PDBTitle: the crystal structure of an alpha-(1-3,4)-fucosidase from2 bifidobacterium longum subsp. infantis atcc 15697 Phyre2 PDB 1v7z chain A Region: 38 - 76 Aligned: 38 Modelled: 39 Confidence: 11.9% Identity: 18% Fold: Creatininase Superfamily: Creatininase Family: Creatininase Phyre2 PDB 1cdw chain A domain 2 Region: 38 - 57 Aligned: 20 Modelled: 20 Confidence: 11.7% Identity: 25% Fold: TBP-like Superfamily: TATA-box binding protein-like Family: TATA-box binding protein (TBP), C-terminal domain Phyre2 PDB 2w1s chain B Region: 64 - 84 Aligned: 21 Modelled: 21 Confidence: 11.5% Identity: 10% PDB header:hydrolase Chain: B: PDB Molecule:hyaluronoglucosaminidase; PDBTitle: unique ligand binding specificity of a family 322 carbohydrate-binding module from the mu toxin produced by3 clostridium perfringens Phyre2 1 d2noca1 2 d2jnaa1 3 c2k4qA_ 4 c3dfeA_ 5 c3dnfB_ 6 d1kjqa1 7 c3ke8A_ 8 c3b9nB_ 9 d3etja1 10 c2y1bA_ 11 c1hl8B_ 12 c3lubE_ 13 c3no4A_ 14 c3eypB_ 15 c2v82A_ 16 c3qkbB_ 17 c3mo4B_ 18 d1v7za_ 19 d1cdwa2 20 c2w1sB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2noca1 100.0 34 Fold:Dodecin subunit-like Superfamily:YdgH-like Family:YdgH-like 2 d2jnaa1 100.0 31 Fold:Dodecin subunit-like Superfamily:YdgH-like Family:YdgH-like 3 c2k4qA_ 54.2 12 PDB header:viral protein Chain: A: PDB Molecule:major tail protein v; PDBTitle: the solution structure of gpv, the major tail protein from2 bacteriophage lambda 4 c3dfeA_ 31.8 38 PDB header:signaling protein Chain: A: PDB Molecule:putative pii-like signaling protein; PDBTitle: crystal structure of a putative pii-like signaling protein2 (yp_323533.1) from anabaena variabilis atcc 29413 at 2.35 a3 resolution 5 c3dnfB_ 26.1 16 PDB header:oxidoreductase Chain: B: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate reductase; PDBTitle: structure of (e)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase,2 the terminal enzyme of the non-mevalonate pathway 6 d1kjqa1 25.7 18 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:BC C-terminal domain-like 7 c3ke8A_ 22.8 17 PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate PDBTitle: crystal structure of isph:hmbpp-complex 8 c3b9nB_ 20.6 16 PDB header:oxidoreductase Chain: B: PDB Molecule:alkane monoxygenase; PDBTitle: crystal structure of long-chain alkane monooxygenase (lada) 9 d3etja1 20.0 26 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:BC C-terminal domain-like 10 c2y1bA_ 20.0 17 PDB header:membrane protein Chain: A: PDB Molecule:putative outer membrane protein, signal; PDBTitle: crystal structure of the e. coli outer membrane lipoprotein2 rcsf 11 c1hl8B_ 19.4 17 PDB header:hydrolase Chain: B: PDB Molecule:putative alpha-l-fucosidase; PDBTitle: crystal structure of thermotoga maritima alpha-fucosidase 12 c3lubE_ 19.3 13 PDB header:hydrolase Chain: E: PDB Molecule:putative creatinine amidohydrolase; PDBTitle: crystal structure of putative creatinine amidohydrolase2 (yp_211512.1) from bacteroides fragilis nctc 9343 at 2.11 a3 resolution 13 c3no4A_ 18.5 18 PDB header:hydrolase Chain: A: PDB Molecule:creatinine amidohydrolase; PDBTitle: crystal structure of a creatinine amidohydrolase (npun_f1913) from2 nostoc punctiforme pcc 73102 at 2.00 a resolution 14 c3eypB_ 14.6 4 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative alpha-l-fucosidase; PDBTitle: crystal structure of putative alpha-l-fucosidase from bacteroides2 thetaiotaomicron 15 c2v82A_ 13.5 6 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase; PDBTitle: kdpgal complexed to kdpgal 16 c3qkbB_ 13.2 24 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a protein with unknown function which belongs to2 pfam duf74 family (pepe_0654) from pediococcus pentosaceus atcc 257453 at 2.73 a resolution 17 c3mo4B_ 13.2 13 PDB header:hydrolase Chain: B: PDB Molecule:alpha-1,3/4-fucosidase; PDBTitle: the crystal structure of an alpha-(1-3,4)-fucosidase from2 bifidobacterium longum subsp. infantis atcc 15697 18 d1v7za_ 11.9 18 Fold:Creatininase Superfamily:Creatininase Family:Creatininase 19 d1cdwa2 11.7 25 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 20 c2w1sB_ 11.5 10 PDB header:hydrolase Chain: B: PDB Molecule:hyaluronoglucosaminidase; PDBTitle: unique ligand binding specificity of a family 322 carbohydrate-binding module from the mu toxin produced by3 clostridium perfringens 21 c2jz7A_ not modelled 10.9 23 PDB header:selenium-binding protein Chain: A: PDB Molecule:selenium binding protein; PDBTitle: solution nmr structure of selenium-binding protein from2 methanococcus vannielii 22 c3eikB_ not modelled 10.5 25 PDB header:transcription Chain: B: PDB Molecule:tata-box-binding protein; PDBTitle: double stranded dna binding protein 23 c1f02T_ not modelled 10.5 33 PDB header:cell adhesion Chain: T: PDB Molecule:translocated intimin receptor; PDBTitle: crystal structure of c-terminal 282-residue fragment of2 intimin in complex with translocated intimin receptor3 (tir) intimin-binding domain 24 d1hl9a2 not modelled 10.4 17 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Putative alpha-L-fucosidase, catalytic domain 25 d1aisa2 not modelled 10.4 20 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 26 c3sdoB_ not modelled 10.0 13 PDB header:oxidoreductase Chain: B: PDB Molecule:nitrilotriacetate monooxygenase; PDBTitle: structure of a nitrilotriacetate monooxygenase from burkholderia2 pseudomallei 27 c2wvsD_ not modelled 9.5 29 PDB header:hydrolase Chain: D: PDB Molecule:alpha-l-fucosidase; PDBTitle: crystal structure of an alpha-l-fucosidase gh29 trapped2 covalent intermediate from bacteroides thetaiotaomicron in3 complex with 2-fluoro-fucosyl fluoride using an e288q4 mutant 28 d1mp9a2 not modelled 9.3 20 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 29 c1mp9B_ not modelled 9.0 20 PDB header:dna binding protein Chain: B: PDB Molecule:tata-binding protein; PDBTitle: tbp from a mesothermophilic archaeon, sulfolobus2 acidocaldarius 30 c1d3uA_ not modelled 8.8 20 PDB header:gene regulation/dna Chain: A: PDB Molecule:tata-binding protein; PDBTitle: tata-binding protein/transcription factor (ii)b/bre+tata-2 box complex from pyrococcus woesei 31 d1nh2a2 not modelled 8.7 17 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 32 d1txka2 not modelled 8.7 29 Fold:Supersandwich Superfamily:Galactose mutarotase-like Family:MdoG-like 33 d1mp9a1 not modelled 8.6 25 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 34 c2z8uQ_ not modelled 8.4 30 PDB header:transcription Chain: Q: PDB Molecule:tata-box-binding protein; PDBTitle: methanococcus jannaschii tbp 35 c1txkA_ not modelled 8.3 29 PDB header:biosynthetic protein Chain: A: PDB Molecule:glucans biosynthesis protein g; PDBTitle: crystal structure of escherichia coli opgg 36 d1luca_ not modelled 8.2 4 Fold:TIM beta/alpha-barrel Superfamily:Bacterial luciferase-like Family:Bacterial luciferase (alkanal monooxygenase) 37 c1ngmM_ not modelled 7.9 20 PDB header:transcription/dna Chain: M: PDB Molecule:transcription initiation factor tfiid; PDBTitle: crystal structure of a yeast brf1-tbp-dna ternary complex 38 c1rm1A_ not modelled 7.9 20 PDB header:transcription/dna Chain: A: PDB Molecule:tata-box binding protein; PDBTitle: structure of a yeast tfiia/tbp/tata-box dna complex 39 d2g39a1 not modelled 7.9 29 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:CoA transferase alpha subunit-like 40 d1qnaa2 not modelled 7.6 17 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 41 d1ycga1 not modelled 7.5 11 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 42 d1lucb_ not modelled 7.5 8 Fold:TIM beta/alpha-barrel Superfamily:Bacterial luciferase-like Family:Bacterial luciferase (alkanal monooxygenase) 43 d1f07a_ not modelled 7.5 23 Fold:TIM beta/alpha-barrel Superfamily:Bacterial luciferase-like Family:F420 dependent oxidoreductases 44 c3ir9A_ not modelled 7.0 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:peptide chain release factor subunit 1; PDBTitle: c-terminal domain of peptide chain release factor from2 methanosarcina mazei. 45 c1oy8A_ not modelled 6.6 12 PDB header:membrane protein Chain: A: PDB Molecule:acriflavine resistance protein b; PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump 46 d1nh2a1 not modelled 6.4 30 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 47 c2k38A_ not modelled 6.2 38 PDB header:antimicrobial protein Chain: A: PDB Molecule:cupiennin-1a; PDBTitle: cupiennin 1a, nmr, minimized average structure 48 d1uqra_ not modelled 6.0 45 Fold:Flavodoxin-like Superfamily:Type II 3-dehydroquinate dehydratase Family:Type II 3-dehydroquinate dehydratase 49 d1gqoa_ not modelled 6.0 30 Fold:Flavodoxin-like Superfamily:Type II 3-dehydroquinate dehydratase Family:Type II 3-dehydroquinate dehydratase 50 c2zfdB_ not modelled 5.9 12 PDB header:signaling protein/transferase Chain: B: PDB Molecule:putative uncharacterized protein t20l15_90; PDBTitle: the crystal structure of plant specific calcium binding protein atcbl22 in complex with the regulatory domain of atcipk14 51 d1aisa1 not modelled 5.7 35 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 52 c3gzaB_ not modelled 5.7 21 PDB header:hydrolase Chain: B: PDB Molecule:putative alpha-l-fucosidase; PDBTitle: crystal structure of putative alpha-l-fucosidase (np_812709.1) from2 bacteroides thetaiotaomicron vpi-5482 at 1.60 a resolution 53 c3n8kG_ not modelled 5.3 25 PDB header:lyase Chain: G: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: type ii dehydroquinase from mycobacterium tuberculosis complexed with2 citrazinic acid 54 c2uygF_ not modelled 5.3 27 PDB header:lyase Chain: F: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystallogaphic structure of the typeii 3-dehydroquinase2 from thermus thermophilus 55 c2cokA_ not modelled 5.2 15 PDB header:transferase Chain: A: PDB Molecule:poly [adp-ribose] polymerase-1; PDBTitle: solution structure of brct domain of poly(adp-ribose)2 polymerase-1

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0