Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	A	T	A	A	Q	T	K	S	L	E	W	L	N	R	L	R	A	N	P	K	I	P	L	I	V	A	G	S	A	A	V	A	V	M	V	A	L	I	L	W	A	K	A	P	D	Y	R	T	L	F	S	N	L	S	D	Q	D	G
Secondary structure
SS confidence
Disorder		?	?	?	?													?		?		?	?																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	A	I	V	S	Q	L	T	Q	M	N	I	P	Y	R	F	S	E	A	S	G	A	I	E	V	P	A	D	K	V	H	E	L	R	L	R	L	A	Q	Q	G	L	P	K	G	G	A	V	G	F	E	L	L	D	Q	E	K	F	G	I
Secondary structure
SS confidence
Disorder														?						?	?	?																			?	?	?	?	?	?	?	?	?	?	?	?			?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		S	Q	F	S	E	Q	V	N	Y	Q	R	A	L	E	G	E	L	S	R	T	I	E	T	I	G	P	V	K	G	A	R	V	H	L	A	M	P	K	P	S	L	F	V	R	E	Q	K	S	P	S	A	S	V	T	V	N	L	L	P	G
Secondary structure
SS confidence
Disorder		?																						?	?	?	?	?	?	?										?	?	?	?	?	?	?	?	?											?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		R	A	L	D	E	G	Q	I	S	A	I	V	H	L	V	S	S	A	V	A	G	L	P	P	G	N	V	T	L	V	D	Q	G	G	H	L	L	T	Q	S	N	T	S	G	R	D	L	N	D	A	Q	L	K	Y	A	S	D	V	E	G
Secondary structure
SS confidence
Disorder		?	?	?	?																														?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		R	I	Q	R	R	I	E	A	I	L	S	P	I	V	G	N	G	N	I	H	A	Q	V	T	A	Q	L	D	F	A	S	K	E	Q	T	E	E	Q	Y	R	P	N	G	D	E	S	H	A	A	L	R	S	R	Q	L	N	E	S	E	Q
Secondary structure
SS confidence
Disorder																																	?								?	?	?	?	?	?	?	?	?	?									?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		S	G	S	G	Y	P	G	G	V	P	G	A	L	S	N	Q	P	A	P	A	N	N	A	P	I	S	T	P	P	A	N	Q	N	N	R	Q	Q	Q	A	S	T	T	S	N	S	G	P	R	S	T	Q	R	N	E	T	S	N	Y	E	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		D	R	T	I	R	H	T	K	M	N	V	G	D	V	Q	R	L	S	V	A	V	V	V	N	Y	K	T	L	P	D	G	K	P	L	P	L	S	N	E	Q	M	K	Q	I	E	D	L	T	R	E	A	M	G	F	S	E	K	R	G	D
Secondary structure
SS confidence
Disorder										?	?	?																?	?	?	?	?	?	?	?	?	?																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		S	L	N	V	V	N	S	P	F	N	S	S	D	E	S	G	G	E	L	P	F	W	Q	Q	Q	A	F	I	D	Q	L	L	A	A	G	R	W	L	L	V	L	L	V	A	W	L	L	W	R	K	A	V	R	P	Q	L	T	R	R	A
Secondary structure
SS confidence
Disorder									?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																																		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		E	A	M	K	A	V	Q	Q	Q	A	Q	A	R	E	E	V	E	D	A	V	E	V	R	L	S	K	D	E	Q	L	Q	Q	R	R	A	N	Q	R	L	G	A	E	V	M	S	Q	R	I	R	E	M	S	D	N	D	P	R	V	V	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.
Sequence		L	V	I	R	Q	W	I	N	N	D	H	E
Secondary structure
SS confidence
Disorder									?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2y9j chain T Region: 49 - 212 Aligned: 163 Modelled: 164 Confidence: 100.0% Identity: 21% PDB header:protein transport Chain: T: PDB Molecule:protein prgh; PDBTitle: three-dimensional model of salmonella's needle complex at2 subnanometer resolution Phyre2 PDB 1yj7 chain A Region: 49 - 214 Aligned: 148 Modelled: 166 Confidence: 100.0% Identity: 24% PDB header:protein transport Chain: A: PDB Molecule:escj; PDBTitle: crystal structure of enteropathogenic e.coli (epec) type iii secretion2 system protein escj Phyre2 PDB 2hfv chain A Region: 45 - 102 Aligned: 58 Modelled: 58 Confidence: 92.5% Identity: 22% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein rpa1041; PDBTitle: solution nmr structure of protein rpa1041 from pseudomonas2 aeruginosa. northeast structural genomics consortium3 target pat90. Phyre2 PDB 2hfv chain A domain 1 Region: 48 - 102 Aligned: 55 Modelled: 55 Confidence: 86.7% Identity: 24% Fold: Ferredoxin-like Superfamily: GlnB-like Family: RPA1041-like Phyre2 PDB 1yqh chain A domain 1 Region: 58 - 104 Aligned: 47 Modelled: 47 Confidence: 80.7% Identity: 13% Fold: Ferredoxin-like Superfamily: MTH1187/YkoF-like Family: MTH1187-like Phyre2 PDB 1lxn chain A Region: 57 - 104 Aligned: 48 Modelled: 48 Confidence: 79.1% Identity: 23% Fold: Ferredoxin-like Superfamily: MTH1187/YkoF-like Family: MTH1187-like Phyre2 PDB 1vk8 chain A Region: 58 - 93 Aligned: 36 Modelled: 36 Confidence: 78.0% Identity: 6% Fold: Ferredoxin-like Superfamily: MTH1187/YkoF-like Family: MTH1187-like Phyre2 PDB 1lxj chain A Region: 57 - 104 Aligned: 48 Modelled: 48 Confidence: 77.8% Identity: 17% Fold: Ferredoxin-like Superfamily: MTH1187/YkoF-like Family: MTH1187-like Phyre2 PDB 2ibo chain A domain 1 Region: 58 - 93 Aligned: 36 Modelled: 33 Confidence: 71.4% Identity: 8% Fold: Ferredoxin-like Superfamily: MTH1187/YkoF-like Family: MTH1187-like Phyre2 PDB 2epi chain A Region: 57 - 93 Aligned: 37 Modelled: 37 Confidence: 63.4% Identity: 5% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0045 protein mj1052; PDBTitle: crystal structure pf hypothetical protein mj1052 from2 methanocaldococcus jannascii (form 2) Phyre2 PDB 2rdd chain B Region: 453 - 488 Aligned: 36 Modelled: 36 Confidence: 60.4% Identity: 19% PDB header:membrane protein/transport protein Chain: B: PDB Molecule:upf0092 membrane protein yajc; PDBTitle: x-ray crystal structure of acrb in complex with a novel2 transmembrane helix. Phyre2 PDB 1oy8 chain A Region: 136 - 271 Aligned: 115 Modelled: 136 Confidence: 54.5% Identity: 12% PDB header:membrane protein Chain: A: PDB Molecule:acriflavine resistance protein b; PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump Phyre2 PDB 2flz chain C Region: 129 - 210 Aligned: 82 Modelled: 82 Confidence: 53.9% Identity: 12% PDB header:hydrolase Chain: C: PDB Molecule:cis-3-chloroacrylic acid dehalogenase; PDBTitle: the x-ray structure of cis-3-chloroacrylic acid dehalogenase (cis-2 caad) with a sulfate ion bound in the active site Phyre2 PDB 2yzc chain A domain 1 Region: 114 - 176 Aligned: 63 Modelled: 63 Confidence: 52.2% Identity: 19% Fold: T-fold Superfamily: Tetrahydrobiopterin biosynthesis enzymes-like Family: Urate oxidase (uricase) Phyre2 PDB 1b6g chain A Region: 534 - 550 Aligned: 17 Modelled: 17 Confidence: 48.1% Identity: 6% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Haloalkane dehalogenase Phyre2 PDB 2h7x chain A Region: 531 - 549 Aligned: 19 Modelled: 19 Confidence: 47.9% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:type i polyketide synthase pikaiv; PDBTitle: pikromycin thioesterase adduct with reduced triketide2 affinity label Phyre2 PDB 2h7x chain A domain 1 Region: 531 - 549 Aligned: 19 Modelled: 19 Confidence: 41.8% Identity: 21% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Thioesterase domain of polypeptide, polyketide and fatty acid synthases Phyre2 PDB 3g7s chain A Region: 135 - 212 Aligned: 60 Modelled: 78 Confidence: 40.8% Identity: 22% PDB header:ligase Chain: A: PDB Molecule:long-chain-fatty-acid--coa ligase (fadd-1); PDBTitle: crystal structure of a long-chain-fatty-acid-coa ligase2 (fadd1) from archaeoglobus fulgidus Phyre2 PDB 2b61 chain A domain 1 Region: 534 - 550 Aligned: 17 Modelled: 17 Confidence: 40.4% Identity: 18% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: O-acetyltransferase Phyre2 PDB 3hd7 chain A Region: 13 - 44 Aligned: 28 Modelled: 32 Confidence: 37.8% Identity: 18% PDB header:exocytosis Chain: A: PDB Molecule:vesicle-associated membrane protein 2; PDBTitle: helical extension of the neuronal snare complex into the membrane,2 spacegroup c 1 2 1 Phyre2 1 c2y9jt_ 2 c1yj7A_ 3 c2hfvA_ 4 d2hfva1 5 d1yqha1 6 d1lxna_ 7 d1vk8a_ 8 d1lxja_ 9 d2iboa1 10 c2epiA_ 11 c2rddB_ 12 c1oy8A_ 13 c2flzC_ 14 d2yzca1 15 d1b6ga_ 16 c2h7xA_ 17 d2h7xa1 18 c3g7sA_ 19 d2b61a1 20 c3hd7A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2y9jt_ 100.0 21 PDB header:protein transport Chain: T: PDB Molecule:protein prgh; PDBTitle: three-dimensional model of salmonella's needle complex at2 subnanometer resolution 2 c1yj7A_ 100.0 24 PDB header:protein transport Chain: A: PDB Molecule:escj; PDBTitle: crystal structure of enteropathogenic e.coli (epec) type iii secretion2 system protein escj 3 c2hfvA_ 92.5 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein rpa1041; PDBTitle: solution nmr structure of protein rpa1041 from pseudomonas2 aeruginosa. northeast structural genomics consortium3 target pat90. 4 d2hfva1 86.7 24 Fold:Ferredoxin-like Superfamily:GlnB-like Family:RPA1041-like 5 d1yqha1 80.7 13 Fold:Ferredoxin-like Superfamily:MTH1187/YkoF-like Family:MTH1187-like 6 d1lxna_ 79.1 23 Fold:Ferredoxin-like Superfamily:MTH1187/YkoF-like Family:MTH1187-like 7 d1vk8a_ 78.0 6 Fold:Ferredoxin-like Superfamily:MTH1187/YkoF-like Family:MTH1187-like 8 d1lxja_ 77.8 17 Fold:Ferredoxin-like Superfamily:MTH1187/YkoF-like Family:MTH1187-like 9 d2iboa1 71.4 8 Fold:Ferredoxin-like Superfamily:MTH1187/YkoF-like Family:MTH1187-like 10 c2epiA_ 63.4 5 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0045 protein mj1052; PDBTitle: crystal structure pf hypothetical protein mj1052 from2 methanocaldococcus jannascii (form 2) 11 c2rddB_ 60.4 19 PDB header:membrane protein/transport protein Chain: B: PDB Molecule:upf0092 membrane protein yajc; PDBTitle: x-ray crystal structure of acrb in complex with a novel2 transmembrane helix. 12 c1oy8A_ 54.5 12 PDB header:membrane protein Chain: A: PDB Molecule:acriflavine resistance protein b; PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump 13 c2flzC_ 53.9 12 PDB header:hydrolase Chain: C: PDB Molecule:cis-3-chloroacrylic acid dehalogenase; PDBTitle: the x-ray structure of cis-3-chloroacrylic acid dehalogenase (cis-2 caad) with a sulfate ion bound in the active site 14 d2yzca1 52.2 19 Fold:T-fold Superfamily:Tetrahydrobiopterin biosynthesis enzymes-like Family:Urate oxidase (uricase) 15 d1b6ga_ 48.1 6 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloalkane dehalogenase 16 c2h7xA_ 47.9 21 PDB header:hydrolase Chain: A: PDB Molecule:type i polyketide synthase pikaiv; PDBTitle: pikromycin thioesterase adduct with reduced triketide2 affinity label 17 d2h7xa1 41.8 21 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Thioesterase domain of polypeptide, polyketide and fatty acid synthases 18 c3g7sA_ 40.8 22 PDB header:ligase Chain: A: PDB Molecule:long-chain-fatty-acid--coa ligase (fadd-1); PDBTitle: crystal structure of a long-chain-fatty-acid-coa ligase2 (fadd1) from archaeoglobus fulgidus 19 d2b61a1 40.4 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 20 c3hd7A_ 37.8 18 PDB header:exocytosis Chain: A: PDB Molecule:vesicle-associated membrane protein 2; PDBTitle: helical extension of the neuronal snare complex into the membrane,2 spacegroup c 1 2 1 21 c3n4dF_ not modelled 36.4 16 PDB header:hydrolase Chain: F: PDB Molecule:putative tautomerase; PDBTitle: crystal structure of cg10062 inactivated by(r)-oxirane-2-carboxylate 22 d1cr6a2 not modelled 35.1 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Epoxide hydrolase 23 c1zhvA_ not modelled 33.7 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein atu0741; PDBTitle: x-ray crystal structure protein atu0741 from agobacterium tumefaciens.2 northeast structural genomics consortium target atr8. 24 c2xuaH_ not modelled 33.2 0 PDB header:hydrolase Chain: H: PDB Molecule:3-oxoadipate enol-lactonase; PDBTitle: crystal structure of the enol-lactonase from burkholderia2 xenovorans lb400 25 d1otfa_ not modelled 33.0 14 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:4-oxalocrotonate tautomerase-like 26 d1zhva2 not modelled 32.8 19 Fold:Ferredoxin-like Superfamily:ACT-like Family:Atu0741-like 27 c3bf7B_ not modelled 32.5 26 PDB header:hydrolase Chain: B: PDB Molecule:esterase ybff; PDBTitle: 1.1 resolution structure of ybff, a new esterase from2 escherichia coli: a unique substrate-binding crevice3 generated by domain arrangement 28 c3etcB_ not modelled 31.7 14 PDB header:ligase Chain: B: PDB Molecule:amp-binding protein; PDBTitle: 2.1 a structure of acyl-adenylate synthetase from methanosarcina2 acetivorans containing a link between lys256 and cys298 29 d1gksa_ not modelled 30.1 10 Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c 30 d1r3da_ not modelled 29.8 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hypothetical protein VC1974 31 c2yzbA_ not modelled 29.3 19 PDB header:oxidoreductase Chain: A: PDB Molecule:uricase; PDBTitle: crystal structure of uricase from arthrobacter globiformis2 in complex with uric acid (substrate) 32 c3lcrA_ not modelled 28.7 12 PDB header:hydrolase Chain: A: PDB Molecule:tautomycetin biosynthetic pks; PDBTitle: thioesterase from tautomycetin biosynthhetic pathway 33 c2aj1A_ not modelled 28.5 28 PDB header:hydrolase Chain: A: PDB Molecule:probable cadmium-transporting atpase; PDBTitle: solution structure of apocada 34 d1ic8a2 not modelled 28.2 15 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:POU-specific domain 35 c3l80A_ not modelled 27.0 9 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein smu.1393c; PDBTitle: crystal structure of smu.1393c from streptococcus mutans ua159 36 c3gacD_ not modelled 26.8 13 PDB header:cytokine Chain: D: PDB Molecule:macrophage migration inhibitory factor-like PDBTitle: structure of mif with hpp 37 c1y37A_ not modelled 26.8 21 PDB header:hydrolase Chain: A: PDB Molecule:fluoroacetate dehalogenase; PDBTitle: structure of fluoroacetate dehalogenase from burkholderia sp. fa1 38 d1qlwa_ not modelled 26.2 39 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:A novel bacterial esterase 39 d1bjpa_ not modelled 26.1 25 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:4-oxalocrotonate tautomerase-like 40 c2kncB_ not modelled 25.9 30 PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-3; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex 41 c3fwtA_ not modelled 25.6 15 PDB header:cytokine Chain: A: PDB Molecule:macrophage migration inhibitory factor-like PDBTitle: crystal structure of leishmania major mif2 42 d1pg4a_ not modelled 25.6 17 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 43 c3ol4B_ not modelled 25.5 23 PDB header:unknown function Chain: B: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of a putative uncharacterized protein from2 mycobacterium smegmatis, an ortholog of rv0543c 44 d1mo2a_ not modelled 25.3 22 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Thioesterase domain of polypeptide, polyketide and fatty acid synthases 45 c1mo2A_ not modelled 25.3 22 PDB header:transferase Chain: A: PDB Molecule:erythronolide synthase, modules 5 and 6; PDBTitle: thioesterase domain from 6-deoxyerythronolide synthase2 (debs te), ph 8.5 46 c3ry0A_ not modelled 25.1 25 PDB header:isomerase Chain: A: PDB Molecule:putative tautomerase; PDBTitle: crystal structure of tomn, a 4-oxalocrotonate tautomerase homologue in2 tomaymycin biosynthetic pathway 47 c3fobA_ not modelled 25.1 0 PDB header:oxidoreductase Chain: A: PDB Molecule:bromoperoxidase; PDBTitle: crystal structure of bromoperoxidase from bacillus anthracis 48 d2rhwa1 not modelled 24.7 0 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carbon-carbon bond hydrolase 49 c1j2gC_ not modelled 24.6 10 PDB header:oxidoreductase Chain: C: PDB Molecule:uricase; PDBTitle: crystal structure of urate oxidase from bacillus sp. tb-90 co-2 crystallized with 8-azaxanthine 50 c2xmzA_ not modelled 24.6 10 PDB header:lyase Chain: A: PDB Molecule:hydrolase, alpha/beta hydrolase fold family; PDBTitle: structure of menh from s. aureus 51 c2vavL_ not modelled 24.3 13 PDB header:transferase Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak) 52 d2hmfa2 not modelled 23.0 8 Fold:Ferredoxin-like Superfamily:ACT-like Family:Aspartokinase allosteric domain-like 53 c2xczA_ not modelled 22.5 13 PDB header:immune system Chain: A: PDB Molecule:possible atls1-like light-inducible protein; PDBTitle: crystal structure of macrophage migration inhibitory factor2 homologue from prochlorococcus marinus 54 d1u1ia1 not modelled 22.3 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 55 c2op8A_ not modelled 21.8 33 PDB header:isomerase Chain: A: PDB Molecule:probable tautomerase ywhb; PDBTitle: crystal structure of ywhb- homologue of 4-oxalocrotonate tautomerase 56 d1uaaa2 not modelled 21.6 20 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 57 c2kt2A_ not modelled 21.4 22 PDB header:oxidoreductase Chain: A: PDB Molecule:mercuric reductase; PDBTitle: structure of nmera, the n-terminal hma domain of tn501 mercuric2 reductase 58 d1eh1a_ not modelled 21.0 16 Fold:RRF/tRNA synthetase additional domain-like Superfamily:Ribosome recycling factor, RRF Family:Ribosome recycling factor, RRF 59 d2vata1 not modelled 20.8 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 60 c1yy7A_ not modelled 20.4 21 PDB header:transcription Chain: A: PDB Molecule:stringent starvation protein a; PDBTitle: crystal structure of stringent starvation protein a (sspa),2 an rna polymerase-associated transcription factor 61 d1is1a_ not modelled 20.3 11 Fold:RRF/tRNA synthetase additional domain-like Superfamily:Ribosome recycling factor, RRF Family:Ribosome recycling factor, RRF 62 c1cr6A_ not modelled 20.2 18 PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase; PDBTitle: crystal structure of murine soluble epoxide hydrolase2 complexed with cpu inhibitor 63 c2ronA_ not modelled 20.1 20 PDB header:hydrolase Chain: A: PDB Molecule:surfactin synthetase thioesterase subunit; PDBTitle: the external thioesterase of the surfactin-synthetase 64 d1dd5a_ not modelled 20.0 5 Fold:RRF/tRNA synthetase additional domain-like Superfamily:Ribosome recycling factor, RRF Family:Ribosome recycling factor, RRF 65 c3mlcC_ not modelled 20.0 13 PDB header:isomerase Chain: C: PDB Molecule:fg41 malonate semialdehyde decarboxylase; PDBTitle: crystal structure of fg41msad inactivated by 3-chloropropiolate 66 c2kkhA_ not modelled 19.8 17 PDB header:metal transport Chain: A: PDB Molecule:putative heavy metal transporter; PDBTitle: structure of the zinc binding domain of the atpase hma4 67 d1w36b2 not modelled 19.7 16 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 68 d1z3ea1 not modelled 19.4 19 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:ArsC-like 69 d1uk8a_ not modelled 19.1 5 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carbon-carbon bond hydrolase 70 c2cjpA_ not modelled 18.7 21 PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase; PDBTitle: structure of potato (solanum tuberosum) epoxide hydrolase i2 (steh1) 71 d1ek8a_ not modelled 18.7 13 Fold:RRF/tRNA synthetase additional domain-like Superfamily:Ribosome recycling factor, RRF Family:Ribosome recycling factor, RRF 72 c2f06B_ not modelled 18.3 6 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of protein bt0572 from bacteroides thetaiotaomicron 73 c3qyjB_ not modelled 18.2 11 PDB header:hydrolase Chain: B: PDB Molecule:alr0039 protein; PDBTitle: crystal structure of alr0039, a putative alpha/beta hydrolase from2 nostoc sp pcc 7120. 74 c2rogA_ not modelled 18.2 16 PDB header:metal binding protein Chain: A: PDB Molecule:heavy metal binding protein; PDBTitle: solution structure of thermus thermophilus hb8 ttha17182 protein in living e. coli cells 75 c3b64A_ not modelled 18.2 14 PDB header:cytokine Chain: A: PDB Molecule:macrophage migration inhibitory factor-like PDBTitle: macrophage migration inhibitory factor (mif) from2 /leishmania major 76 d1a8qa_ not modelled 18.0 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 77 c3h3yF_ not modelled 17.8 12 PDB header:viral protein Chain: F: PDB Molecule:baseplate structural protein gp6; PDBTitle: fitting of the gp6 crystal structure into 3d cryo-em2 reconstruction of bacteriophage t4 star-shaped baseplate 78 c3a2nF_ not modelled 17.4 11 PDB header:hydrolase Chain: F: PDB Molecule:haloalkane dehalogenase; PDBTitle: crystal structure of dbja (wild type type ii p21) 79 c2g29A_ not modelled 17.3 10 PDB header:transport protein Chain: A: PDB Molecule:nitrate transport protein nrta; PDBTitle: crystal structure of the periplasmic nitrate-binding2 protein nrta from synechocystis pcc 6803 80 d1osda_ not modelled 17.2 17 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 81 c2k2pA_ not modelled 17.1 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein atu1203; PDBTitle: solution nmr structure of protein atu1203 from agrobacterium2 tumefaciens. northeast structural genomics consortium (nesg) target3 att10, ontario center for structural proteomics target atc1183 82 c3l78A_ not modelled 17.0 17 PDB header:transcription Chain: A: PDB Molecule:regulatory protein spx; PDBTitle: the crystal structure of smu.1142c from streptococcus mutans ua159 83 d1gyxa_ not modelled 17.0 16 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:4-oxalocrotonate tautomerase-like 84 c3mb2G_ not modelled 17.0 25 PDB header:isomerase Chain: G: PDB Molecule:4-oxalocrotonate tautomerase family enzyme - alpha subunit; PDBTitle: kinetic and structural characterization of a heterohexamer 4-2 oxalocrotonate tautomerase from chloroflexus aurantiacus j-10-fl:3 implications for functional and structural diversity in the4 tautomerase superfamily 85 d1sb6a_ not modelled 16.6 10 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 86 d2aw0a_ not modelled 16.4 33 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 87 c2dahA_ not modelled 16.2 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:ubiquilin-3; PDBTitle: solution structure of the c-terminal uba domain in the2 human ubiquilin 3 88 c2l3mA_ not modelled 16.2 21 PDB header:metal binding protein Chain: A: PDB Molecule:copper-ion-binding protein; PDBTitle: solution structure of the putative copper-ion-binding protein from2 bacillus anthracis str. ames 89 d2qifa1 not modelled 16.1 16 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 90 d2pl5a1 not modelled 16.1 6 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 91 d2ddha2 not modelled 16.0 23 Fold:Bromodomain-like Superfamily:Acyl-CoA dehydrogenase C-terminal domain-like Family:acyl-CoA oxidase C-terminal domains 92 d1q8la_ not modelled 16.0 20 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 93 c1yg0A_ not modelled 16.0 17 PDB header:metal transport Chain: A: PDB Molecule:cop associated protein; PDBTitle: solution structure of apo-copp from helicobacter pylori 94 d1n6za_ not modelled 15.8 15 Fold:Hypothetical protein Yml108w Superfamily:Hypothetical protein Yml108w Family:Hypothetical protein Yml108w 95 c1sr9A_ not modelled 15.7 22 PDB header:transferase Chain: A: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of leua from mycobacterium tuberculosis 96 c2l9bA_ not modelled 15.6 19 PDB header:transcription Chain: A: PDB Molecule:mrna 3'-end-processing protein rna15; PDBTitle: heterodimer between rna14p monkeytail domain and rna15p hinge domain2 of the yeast cf ia complex 97 c3fsgC_ not modelled 15.6 5 PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta superfamily hydrolase; PDBTitle: crystal structure of alpha/beta superfamily hydrolase from oenococcus2 oeni psu-1 98 d1pyya1 not modelled 15.4 13 Fold:Penicillin-binding protein 2x (pbp-2x), c-terminal domain Superfamily:Penicillin-binding protein 2x (pbp-2x), c-terminal domain Family:Penicillin-binding protein 2x (pbp-2x), c-terminal domain 99 d2i52a1 not modelled 15.4 17 Fold:MK0786-like Superfamily:MK0786-like Family:MK0786-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0