Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	G	L	K	Q	E	L	G	L	A	Q	G	I	G	L	L	S	T	S	L	L	G	T	G	V	F	A	V	P	A	L	A	A	L	V	A	G	N	N	S	L	W	A	W	P	V	L	I	I	L	V	F	P	I	A	I	V	F	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	L	G	R	H	Y	P	S	A	G	G	V	A	H	F	V	G	M	A	F	G	S	R	L	E	R	V	T	G	W	L	F	L	S	V	I	P	V	G	L	P	A	A	L	Q	I	A	A	G	F	G	Q	A	M	F	G	W	H	S	W
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Q	L	L	L	A	E	L	G	T	L	A	L	V	W	Y	I	G	T	R	G	A	S	S	S	A	N	L	Q	T	V	I	A	G	L	I	V	A	L	I	V	A	I	W	W	A	G	D	I	K	P	A	N	I	P	F	P	A	P	G	N
Secondary structure
SS confidence
Disorder																																																					?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		I	E	L	T	G	L	F	A	A	L	S	V	M	F	W	C	F	V	G	L	E	A	F	A	H	L	A	S	E	F	K	N	P	E	R	D	F	P	R	A	L	M	I	G	L	L	L	A	G	L	V	Y	W	G	C	T	V	V	V	L
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		H	F	D	A	Y	G	E	K	M	A	A	A	A	S	L	P	K	I	V	V	Q	L	F	G	V	G	A	L	W	I	A	C	V	I	G	Y	L	A	C	F	A	S	L	N	I	Y	I	Q	S	F	A	R	L	V	W	S	Q	A	Q	H
Secondary structure
SS confidence
Disorder									?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		N	P	D	H	Y	L	A	R	L	S	S	R	H	I	P	N	N	A	L	N	A	V	L	G	C	C	V	V	S	T	L	V	I	H	A	L	E	I	N	L	D	A	L	I	I	Y	A	N	G	I	F	I	M	I	Y	L	L	C	M	L
Secondary structure
SS confidence
Disorder									?																										?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.
Sequence		A	G	C	K	L	L	Q	G	R	Y	R	L	L	A	V	V	G	G	L	L	C	V	L	L	L	A	M	V	G	W	K	S	L	Y	A	L	I	M	L	A	G	L	W	L	L	L	P	K	R	K	T	P	E	N	G	I	T	T
Secondary structure
SS confidence
Disorder																																																			?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3gia chain A Region: 5 - 414 Aligned: 404 Modelled: 404 Confidence: 100.0% Identity: 17% PDB header:transport protein Chain: A: PDB Molecule:uncharacterized protein mj0609; PDBTitle: crystal structure of apct transporter Phyre2 PDB 3lrc chain C Region: 5 - 414 Aligned: 389 Modelled: 389 Confidence: 100.0% Identity: 21% PDB header:transport protein Chain: C: PDB Molecule:arginine/agmatine antiporter; PDBTitle: structure of e. coli adic (p1) Phyre2 PDB 2jln chain A Region: 2 - 415 Aligned: 404 Modelled: 404 Confidence: 99.9% Identity: 9% PDB header:membrane protein Chain: A: PDB Molecule:mhp1; PDBTitle: structure of mhp1, a nucleobase-cation-symport-1 family2 transporter Phyre2 PDB 2xq2 chain A Region: 6 - 418 Aligned: 407 Modelled: 407 Confidence: 99.1% Identity: 13% PDB header:transport protein Chain: A: PDB Molecule:sodium/glucose cotransporter; PDBTitle: structure of the k294a mutant of vsglt Phyre2 PDB 3dh4 chain A Region: 6 - 418 Aligned: 407 Modelled: 410 Confidence: 98.9% Identity: 12% PDB header:transport protein Chain: A: PDB Molecule:sodium/glucose cotransporter; PDBTitle: crystal structure of sodium/sugar symporter with bound galactose from2 vibrio parahaemolyticus Phyre2 PDB 2w8a chain C Region: 2 - 374 Aligned: 364 Modelled: 366 Confidence: 97.0% Identity: 16% PDB header:membrane protein Chain: C: PDB Molecule:glycine betaine transporter betp; PDBTitle: crystal structure of the sodium-coupled glycine betaine2 symporter betp from corynebacterium glutamicum with bound3 substrate Phyre2 PDB 2a65 chain A domain 1 Region: 9 - 411 Aligned: 394 Modelled: 394 Confidence: 96.6% Identity: 13% Fold: SNF-like Superfamily: SNF-like Family: SNF-like Phyre2 PDB 3hfx chain A Region: 39 - 371 Aligned: 327 Modelled: 327 Confidence: 95.2% Identity: 11% PDB header:transport protein Chain: A: PDB Molecule:l-carnitine/gamma-butyrobetaine antiporter; PDBTitle: crystal structure of carnitine transporter Phyre2 PDB 2knc chain A Region: 382 - 415 Aligned: 34 Modelled: 34 Confidence: 15.0% Identity: 24% PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex Phyre2 PDB 1m57 chain H Region: 340 - 417 Aligned: 78 Modelled: 78 Confidence: 13.2% Identity: 17% PDB header:oxidoreductase Chain: H: PDB Molecule:cytochrome c oxidase; PDBTitle: structure of cytochrome c oxidase from rhodobacter2 sphaeroides (eq(i-286) mutant)) Phyre2 PDB 1fft chain C Region: 145 - 280 Aligned: 136 Modelled: 136 Confidence: 10.5% Identity: 13% Fold: Cytochrome c oxidase subunit III-like Superfamily: Cytochrome c oxidase subunit III-like Family: Cytochrome c oxidase subunit III-like Phyre2 PDB 1fft chain B domain 2 Region: 340 - 393 Aligned: 54 Modelled: 54 Confidence: 10.2% Identity: 9% Fold: Transmembrane helix hairpin Superfamily: Cytochrome c oxidase subunit II-like, transmembrane region Family: Cytochrome c oxidase subunit II-like, transmembrane region Phyre2 PDB 1qle chain B Region: 340 - 418 Aligned: 79 Modelled: 79 Confidence: 9.9% Identity: 10% PDB header:oxidoreductase/immune system Chain: B: PDB Molecule:cytochrome c oxidase polypeptide ii; PDBTitle: cryo-structure of the paracoccus denitrificans four-subunit2 cytochrome c oxidase in the completely oxidized state3 complexed with an antibody fv fragment Phyre2 PDB 3ehb chain B domain 2 Region: 340 - 399 Aligned: 60 Modelled: 60 Confidence: 9.4% Identity: 20% Fold: Transmembrane helix hairpin Superfamily: Cytochrome c oxidase subunit II-like, transmembrane region Family: Cytochrome c oxidase subunit II-like, transmembrane region Phyre2 PDB 2k9y chain A Region: 393 - 410 Aligned: 18 Modelled: 18 Confidence: 9.4% Identity: 28% PDB header:transferase Chain: A: PDB Molecule:ephrin type-a receptor 2; PDBTitle: epha2 dimeric structure in the lipidic bicelle at ph 5.0 Phyre2 PDB 2k9y chain B Region: 393 - 410 Aligned: 18 Modelled: 18 Confidence: 9.4% Identity: 28% PDB header:transferase Chain: B: PDB Molecule:ephrin type-a receptor 2; PDBTitle: epha2 dimeric structure in the lipidic bicelle at ph 5.0 Phyre2 PDB 2k1a chain A Region: 382 - 412 Aligned: 31 Modelled: 31 Confidence: 9.1% Identity: 26% PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: bicelle-embedded integrin alpha(iib) transmembrane segment Phyre2 PDB 1dt9 chain A domain 3 Region: 409 - 416 Aligned: 8 Modelled: 8 Confidence: 9.0% Identity: 50% Fold: N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Superfamily: N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Family: N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Phyre2 PDB 2l1u chain A Region: 1 - 9 Aligned: 9 Modelled: 9 Confidence: 8.9% Identity: 22% PDB header:oxidoreductase Chain: A: PDB Molecule:methionine-r-sulfoxide reductase b2, mitochondrial; PDBTitle: structure-functional analysis of mammalian msrb2 protein Phyre2 PDB 3b71 chain E Region: 1 - 9 Aligned: 9 Modelled: 9 Confidence: 8.7% Identity: 44% PDB header:protein binding Chain: E: PDB Molecule:t-cell surface glycoprotein cd4; PDBTitle: cd4 endocytosis motif bound to the focal adhesion targeting (fat)2 domain of the focal adhesion kinase Phyre2 1 c3giaA_ 2 c3lrcC_ 3 c2jlnA_ 4 c2xq2A_ 5 c3dh4A_ 6 c2w8aC_ 7 d2a65a1 8 c3hfxA_ 9 c2kncA_ 10 c1m57H_ 11 d1fftc_ 12 d1fftb2 13 c1qleB_ 14 d3ehbb2 15 c2k9yA_ 16 c2k9yB_ 17 c2k1aA_ 18 d1dt9a3 19 c2l1uA_ 20 c3b71E_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3giaA_ 100.0 17 PDB header:transport protein Chain: A: PDB Molecule:uncharacterized protein mj0609; PDBTitle: crystal structure of apct transporter 2 c3lrcC_ 100.0 21 PDB header:transport protein Chain: C: PDB Molecule:arginine/agmatine antiporter; PDBTitle: structure of e. coli adic (p1) 3 c2jlnA_ 99.9 9 PDB header:membrane protein Chain: A: PDB Molecule:mhp1; PDBTitle: structure of mhp1, a nucleobase-cation-symport-1 family2 transporter 4 c2xq2A_ 99.1 13 PDB header:transport protein Chain: A: PDB Molecule:sodium/glucose cotransporter; PDBTitle: structure of the k294a mutant of vsglt 5 c3dh4A_ 98.9 12 PDB header:transport protein Chain: A: PDB Molecule:sodium/glucose cotransporter; PDBTitle: crystal structure of sodium/sugar symporter with bound galactose from2 vibrio parahaemolyticus 6 c2w8aC_ 97.0 16 PDB header:membrane protein Chain: C: PDB Molecule:glycine betaine transporter betp; PDBTitle: crystal structure of the sodium-coupled glycine betaine2 symporter betp from corynebacterium glutamicum with bound3 substrate 7 d2a65a1 96.6 13 Fold:SNF-like Superfamily:SNF-like Family:SNF-like 8 c3hfxA_ 95.2 11 PDB header:transport protein Chain: A: PDB Molecule:l-carnitine/gamma-butyrobetaine antiporter; PDBTitle: crystal structure of carnitine transporter 9 c2kncA_ 15.0 24 PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex 10 c1m57H_ 13.2 17 PDB header:oxidoreductase Chain: H: PDB Molecule:cytochrome c oxidase; PDBTitle: structure of cytochrome c oxidase from rhodobacter2 sphaeroides (eq(i-286) mutant)) 11 d1fftc_ 10.5 13 Fold:Cytochrome c oxidase subunit III-like Superfamily:Cytochrome c oxidase subunit III-like Family:Cytochrome c oxidase subunit III-like 12 d1fftb2 10.2 9 Fold:Transmembrane helix hairpin Superfamily:Cytochrome c oxidase subunit II-like, transmembrane region Family:Cytochrome c oxidase subunit II-like, transmembrane region 13 c1qleB_ 9.9 10 PDB header:oxidoreductase/immune system Chain: B: PDB Molecule:cytochrome c oxidase polypeptide ii; PDBTitle: cryo-structure of the paracoccus denitrificans four-subunit2 cytochrome c oxidase in the completely oxidized state3 complexed with an antibody fv fragment 14 d3ehbb2 9.4 20 Fold:Transmembrane helix hairpin Superfamily:Cytochrome c oxidase subunit II-like, transmembrane region Family:Cytochrome c oxidase subunit II-like, transmembrane region 15 c2k9yA_ 9.4 28 PDB header:transferase Chain: A: PDB Molecule:ephrin type-a receptor 2; PDBTitle: epha2 dimeric structure in the lipidic bicelle at ph 5.0 16 c2k9yB_ 9.4 28 PDB header:transferase Chain: B: PDB Molecule:ephrin type-a receptor 2; PDBTitle: epha2 dimeric structure in the lipidic bicelle at ph 5.0 17 c2k1aA_ 9.1 26 PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: bicelle-embedded integrin alpha(iib) transmembrane segment 18 d1dt9a3 9.0 50 Fold:N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Superfamily:N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Family:N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 19 c2l1uA_ 8.9 22 PDB header:oxidoreductase Chain: A: PDB Molecule:methionine-r-sulfoxide reductase b2, mitochondrial; PDBTitle: structure-functional analysis of mammalian msrb2 protein 20 c3b71E_ 8.7 44 PDB header:protein binding Chain: E: PDB Molecule:t-cell surface glycoprotein cd4; PDBTitle: cd4 endocytosis motif bound to the focal adhesion targeting (fat)2 domain of the focal adhesion kinase 21 c3b71D_ not modelled 8.7 44 PDB header:protein binding Chain: D: PDB Molecule:t-cell surface glycoprotein cd4; PDBTitle: cd4 endocytosis motif bound to the focal adhesion targeting (fat)2 domain of the focal adhesion kinase 22 c3rceA_ not modelled 8.5 19 PDB header:transferase/peptide Chain: A: PDB Molecule:oligosaccharide transferase to n-glycosylate proteins; PDBTitle: bacterial oligosaccharyltransferase pglb 23 d3dtub2 not modelled 8.3 20 Fold:Transmembrane helix hairpin Superfamily:Cytochrome c oxidase subunit II-like, transmembrane region Family:Cytochrome c oxidase subunit II-like, transmembrane region 24 c3qe7A_ not modelled 8.3 13 PDB header:transport protein Chain: A: PDB Molecule:uracil permease; PDBTitle: crystal structure of uracil transporter--uraa 25 c3e20C_ not modelled 8.0 40 PDB header:translation Chain: C: PDB Molecule:eukaryotic peptide chain release factor subunit 1; PDBTitle: crystal structure of s.pombe erf1/erf3 complex 26 c2kfeA_ not modelled 7.9 56 PDB header:antimicrobial protein Chain: A: PDB Molecule:meucin-24; PDBTitle: solution structure of meucin-24 27 d1xg8a_ not modelled 7.7 5 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:YuzD-like 28 d2obpa1 not modelled 7.7 31 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:ReutB4095-like 29 c2k21A_ not modelled 7.4 10 PDB header:membrane protein Chain: A: PDB Molecule:potassium voltage-gated channel subfamily e PDBTitle: nmr structure of human kcne1 in lmpg micelles at ph 6.0 and2 40 degree c 30 d1t98a2 not modelled 7.2 8 Fold:STAT-like Superfamily:MukF C-terminal domain-like Family:MukF C-terminal domain-like 31 c1ar1B_ not modelled 7.1 20 PDB header:complex (oxidoreductase/antibody) Chain: B: PDB Molecule:cytochrome c oxidase; PDBTitle: structure at 2.7 angstrom resolution of the paracoccus2 denitrificans two-subunit cytochrome c oxidase complexed3 with an antibody fv fragment 32 d2cmyb1 not modelled 7.1 29 Fold:Toxic hairpin Superfamily:VhTI-like Family:VhTI-like 33 c2cmyB_ not modelled 7.1 29 PDB header:hydrolase Chain: B: PDB Molecule:veronica hederifolia trypsin inhibitor; PDBTitle: crystal complex between bovine trypsin and veronica2 hederifolia trypsin inhibitor 34 d1vc4a_ not modelled 6.9 40 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 35 c1ujlA_ not modelled 6.8 11 PDB header:membrane protein Chain: A: PDB Molecule:potassium voltage-gated channel subfamily h PDBTitle: solution structure of the herg k+ channel s5-p2 extracellular linker 36 d1xmec1 not modelled 6.6 23 Fold:Single transmembrane helix Superfamily:Bacterial ba3 type cytochrome c oxidase subunit IIa Family:Bacterial ba3 type cytochrome c oxidase subunit IIa 37 d1ic8a2 not modelled 6.2 15 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:POU-specific domain 38 c3dwuA_ not modelled 6.1 60 PDB header:biosynthetic protein Chain: A: PDB Molecule:elongation factor tu-b; PDBTitle: transition-state model conformation of the switch i region2 fitted into the cryo-em map of the eef2.80s.alf4.gdp3 complex 39 d1a53a_ not modelled 6.0 40 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 40 d1iwpa_ not modelled 6.0 44 Fold:TIM beta/alpha-barrel Superfamily:Cobalamin (vitamin B12)-dependent enzymes Family:Diol dehydratase, alpha subunit 41 d1eexa_ not modelled 6.0 33 Fold:TIM beta/alpha-barrel Superfamily:Cobalamin (vitamin B12)-dependent enzymes Family:Diol dehydratase, alpha subunit 42 c2cpbA_ not modelled 5.9 12 PDB header:viral protein Chain: A: PDB Molecule:m13 major coat protein; PDBTitle: solution nmr structures of the major coat protein of2 filamentous bacteriophage m13 solubilized in3 dodecylphosphocholine micelles, 25 lowest energy structures 43 c1t0fC_ not modelled 5.8 20 PDB header:dna binding protein Chain: C: PDB Molecule:transposon tn7 transposition protein tnsc; PDBTitle: crystal structure of the tnsa/tnsc(504-555) complex 44 c2rddB_ not modelled 5.7 10 PDB header:membrane protein/transport protein Chain: B: PDB Molecule:upf0092 membrane protein yajc; PDBTitle: x-ray crystal structure of acrb in complex with a novel2 transmembrane helix. 45 d1efea_ not modelled 5.6 20 Fold:Insulin-like Superfamily:Insulin-like Family:Insulin-like 46 d2iuba2 not modelled 5.6 20 Fold:Transmembrane helix hairpin Superfamily:Magnesium transport protein CorA, transmembrane region Family:Magnesium transport protein CorA, transmembrane region 47 d1joya_ not modelled 5.5 15 Fold:ROP-like Superfamily:Homodimeric domain of signal transducing histidine kinase Family:Homodimeric domain of signal transducing histidine kinase 48 c1unhD_ not modelled 5.5 11 PDB header:cell cycle Chain: D: PDB Molecule:cyclin-dependent kinase 5 activator 1; PDBTitle: structural mechanism for the inhibition of cdk5-p25 by2 roscovitine, aloisine and indirubin. 49 d1lr7a1 not modelled 5.4 12 Fold:Knottins (small inhibitors, toxins, lectins) Superfamily:EGF/Laminin Family:Follistatin (FS) module N-terminal domain, FS-N 50 d1unld_ not modelled 5.4 11 Fold:Cyclin-like Superfamily:Cyclin-like Family:Cyclin 51 d2nr9a1 not modelled 5.4 9 Fold:Rhomboid-like Superfamily:Rhomboid-like Family:Rhomboid-like 52 d1eah1_ not modelled 5.3 57 Fold:Nucleoplasmin-like/VP (viral coat and capsid proteins) Superfamily:Positive stranded ssRNA viruses Family:Picornaviridae-like VP (VP1, VP2, VP3 and VP4) 53 d1pmxa_ not modelled 5.2 40 Fold:Insulin-like Superfamily:Insulin-like Family:Insulin-like 54 d1j75a_ not modelled 5.2 16 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Z-DNA binding domain 55 c2qtyB_ not modelled 5.1 23 PDB header:hydrolase Chain: B: PDB Molecule:poly(adp-ribose) glycohydrolase arh3; PDBTitle: crystal structure of mouse adp-ribosylhydrolase 3 (marh3)

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0