Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP16703
DateThu Jan 5 11:35:48 GMT 2012
Unique Job ID71ac97380747ddd2

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3pc3A_
Top template information
PDB header:lyase
Chain: A: PDB Molecule:cg1753, isoform a;
PDBTitle: full length structure of cystathionine beta-synthase from drosophila2 in complex with aminoacrylate
Confidence and coverage
Confidence:100.0% Coverage: 99%
299 residues ( 99% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSTLEQTIGNTPLVKLQRMGPDNGSEVWLKLEGNNPAGSVKDRAALSMIVEAEKRGEIKP
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Disorder  ????


















































?????
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   .........70.........80.........90.........100.........110.........120
Sequence  GDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGME
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   .........130.........140.........150.........160.........170.........180
Sequence  GARDLALEMANRGEGKLLDQFNNPDNPYAHYTTTGPEIWQQTGGRITHFVSSMGTTGTIT
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   .........190.........200.........210.........220.........230.........240
Sequence  GVSRFMREQSKPVTIVGLQPEEGSSIPGIRRWPTEYLPGIFNASLVDEVLDIHQRDAENT
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?
???????



























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   .........250.........260.........270.........280.........290.........300
Sequence  MRELAVREGIFCGVSSGGAVAGALRVAKANPDAVVVAIICDRGDRYLSTGVFGEEHFSQG
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??
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   ...
Sequence  AGI
Secondary structure 


SS confidence 


Disorder  ???
Disorder confidence 


 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3pc3 chain A

3D model

Region: 1 - 300
Aligned: 299
Modelled: 300
Confidence: 100.0%
Identity: 37%
PDB header:lyase
Chain: A: PDB Molecule:cg1753, isoform a;
PDBTitle: full length structure of cystathionine beta-synthase from drosophila2 in complex with aminoacrylate

Phyre2

PDB 2bhs chain A domain 1

3D model

Region: 2 - 292
Aligned: 291
Modelled: 291
Confidence: 100.0%
Identity: 100%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 1jbq chain A

3D model

Region: 1 - 300
Aligned: 296
Modelled: 300
Confidence: 100.0%
Identity: 37%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 1jbq chain D

3D model

Region: 1 - 300
Aligned: 296
Modelled: 300
Confidence: 100.0%
Identity: 37%
PDB header:lyase
Chain: D: PDB Molecule:cystathionine beta-synthase;
PDBTitle: structure of human cystathionine beta-synthase: a unique pyridoxal 5'-2 phosphate dependent hemeprotein

Phyre2

PDB 3dwg chain A

3D model

Region: 1 - 300
Aligned: 299
Modelled: 300
Confidence: 100.0%
Identity: 41%
PDB header:transferase
Chain: A: PDB Molecule:cysteine synthase b;
PDBTitle: crystal structure of a sulfur carrier protein complex found in the2 cysteine biosynthetic pathway of mycobacterium tuberculosis

Phyre2

PDB 1z7w chain A domain 1

3D model

Region: 1 - 300
Aligned: 299
Modelled: 300
Confidence: 100.0%
Identity: 45%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 1ve1 chain A domain 1

3D model

Region: 3 - 292
Aligned: 290
Modelled: 290
Confidence: 100.0%
Identity: 46%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 2pqm chain A

3D model

Region: 1 - 295
Aligned: 294
Modelled: 295
Confidence: 100.0%
Identity: 40%
PDB header:lyase
Chain: A: PDB Molecule:cysteine synthase;
PDBTitle: crystal structure of cysteine synthase (oass) from entamoeba2 histolytica at 1.86 a resolution

Phyre2

PDB 2egu chain A

3D model

Region: 1 - 295
Aligned: 265
Modelled: 279
Confidence: 100.0%
Identity: 47%
PDB header:transferase
Chain: A: PDB Molecule:cysteine synthase;
PDBTitle: crystal structure of o-acetylserine sulfhydrase from geobacillus2 kaustophilus hta426

Phyre2

PDB 1y7l chain A domain 1

3D model

Region: 2 - 292
Aligned: 288
Modelled: 289
Confidence: 100.0%
Identity: 42%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 1wkv chain A domain 1

3D model

Region: 1 - 293
Aligned: 288
Modelled: 291
Confidence: 100.0%
Identity: 30%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 2q3b chain A

3D model

Region: 2 - 287
Aligned: 285
Modelled: 286
Confidence: 100.0%
Identity: 43%
PDB header:transferase
Chain: A: PDB Molecule:cysteine synthase a;
PDBTitle: 1.8 a resolution crystal structure of o-acetylserine sulfhydrylase2 (oass) holoenzyme from mycobacterium tuberculosis

Phyre2

PDB 1o58 chain A

3D model

Region: 2 - 289
Aligned: 282
Modelled: 284
Confidence: 100.0%
Identity: 46%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 1tdj chain A

3D model

Region: 2 - 282
Aligned: 274
Modelled: 281
Confidence: 100.0%
Identity: 19%
PDB header:allostery
Chain: A: PDB Molecule:biosynthetic threonine deaminase;
PDBTitle: threonine deaminase (biosynthetic) from e. coli

Phyre2

PDB 1fcj chain A

3D model

Region: 2 - 283
Aligned: 279
Modelled: 282
Confidence: 100.0%
Identity: 42%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 3l6c chain A

3D model

Region: 3 - 289
Aligned: 282
Modelled: 287
Confidence: 100.0%
Identity: 19%
PDB header:isomerase
Chain: A: PDB Molecule:serine racemase;
PDBTitle: x-ray crystal structure of rat serine racemase in complex with2 malonate a potent inhibitor

Phyre2

PDB 2d1f chain A

3D model

Region: 2 - 296
Aligned: 287
Modelled: 291
Confidence: 100.0%
Identity: 23%
PDB header:lyase
Chain: A: PDB Molecule:threonine synthase;
PDBTitle: structure of mycobacterium tuberculosis threonine synthase

Phyre2

PDB 1pwh chain A

3D model

Region: 1 - 302
Aligned: 291
Modelled: 301
Confidence: 100.0%
Identity: 21%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 1tdj chain A domain 1

3D model

Region: 2 - 303
Aligned: 290
Modelled: 302
Confidence: 100.0%
Identity: 18%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2

PDB 1v71 chain A domain 1

3D model

Region: 2 - 299
Aligned: 287
Modelled: 298
Confidence: 100.0%
Identity: 20%
Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes

Phyre2
1

c3pc3A_
2

d2bhsa1
3

d1jbqa_
4

c1jbqD_
5

c3dwgA_
6

d1z7wa1
7

d1ve1a1
8

c2pqmA_
9

c2eguA_
10

d1y7la1
11

d1wkva1
12

c2q3bA_
13

d1o58a_
14

c1tdjA_
15

d1fcja_
16

c3l6cA_
17

c2d1fA_
18

d1pwha_
19

d1tdja1
20

d1v71a1
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3pc3A_



100.0 37 PDB header:lyase
Chain: A: PDB Molecule:cg1753, isoform a;
PDBTitle: full length structure of cystathionine beta-synthase from drosophila2 in complex with aminoacrylate
2d2bhsa1



100.0 100 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
3d1jbqa_



100.0 37 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
4c1jbqD_



100.0 37 PDB header:lyase
Chain: D: PDB Molecule:cystathionine beta-synthase;
PDBTitle: structure of human cystathionine beta-synthase: a unique pyridoxal 5'-2 phosphate dependent hemeprotein
5c3dwgA_



100.0 41 PDB header:transferase
Chain: A: PDB Molecule:cysteine synthase b;
PDBTitle: crystal structure of a sulfur carrier protein complex found in the2 cysteine biosynthetic pathway of mycobacterium tuberculosis
6d1z7wa1



100.0 45 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
7d1ve1a1



100.0 46 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
8c2pqmA_



100.0 40 PDB header:lyase
Chain: A: PDB Molecule:cysteine synthase;
PDBTitle: crystal structure of cysteine synthase (oass) from entamoeba2 histolytica at 1.86 a resolution
9c2eguA_



100.0 47 PDB header:transferase
Chain: A: PDB Molecule:cysteine synthase;
PDBTitle: crystal structure of o-acetylserine sulfhydrase from geobacillus2 kaustophilus hta426
10d1y7la1



100.0 42 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
11d1wkva1



100.0 30 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
12c2q3bA_



100.0 43 PDB header:transferase
Chain: A: PDB Molecule:cysteine synthase a;
PDBTitle: 1.8 a resolution crystal structure of o-acetylserine sulfhydrylase2 (oass) holoenzyme from mycobacterium tuberculosis
13d1o58a_



100.0 46 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
14c1tdjA_



100.0 19 PDB header:allostery
Chain: A: PDB Molecule:biosynthetic threonine deaminase;
PDBTitle: threonine deaminase (biosynthetic) from e. coli
15d1fcja_



100.0 42 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
16c3l6cA_



100.0 19 PDB header:isomerase
Chain: A: PDB Molecule:serine racemase;
PDBTitle: x-ray crystal structure of rat serine racemase in complex with2 malonate a potent inhibitor
17c2d1fA_



100.0 23 PDB header:lyase
Chain: A: PDB Molecule:threonine synthase;
PDBTitle: structure of mycobacterium tuberculosis threonine synthase
18d1pwha_



100.0 21 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
19d1tdja1



100.0 18 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
20d1v71a1



100.0 20 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
21c3iauA_



not modelled 100.0 22 PDB header:lyase
Chain: A: PDB Molecule:threonine deaminase;
PDBTitle: the structure of the processed form of threonine deaminase isoform 22 from solanum lycopersicum
22c2gn0A_



not modelled 100.0 20 PDB header:lyase
Chain: A: PDB Molecule:threonine dehydratase catabolic;
PDBTitle: crystal structure of dimeric biodegradative threonine deaminase (tdcb)2 from salmonella typhimurium at 1.7 a resolution (triclinic form with3 one complete subunit built in alternate conformation)
23c1x1qA_



not modelled 100.0 22 PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase beta chain;
PDBTitle: crystal structure of tryptophan synthase beta chain from thermus2 thermophilus hb8
24d1v7ca_



not modelled 100.0 23 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
25d1p5ja_



not modelled 100.0 19 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
26c1p5jA_



not modelled 100.0 19 PDB header:lyase
Chain: A: PDB Molecule:l-serine dehydratase;
PDBTitle: crystal structure analysis of human serine dehydratase
27d1qopb_



not modelled 100.0 23 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
28d1ve5a1



not modelled 100.0 23 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
29d1v8za1



not modelled 100.0 26 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
30c2rkbE_



not modelled 100.0 22 PDB header:lyase
Chain: E: PDB Molecule:serine dehydratase-like;
PDBTitle: serine dehydratase like-1 from human cancer cells
31c2zsjB_



not modelled 100.0 24 PDB header:lyase
Chain: B: PDB Molecule:threonine synthase;
PDBTitle: crystal structure of threonine synthase from aquifex aeolicus vf5
32c3r0zA_



not modelled 100.0 19 PDB header:lyase
Chain: A: PDB Molecule:d-serine dehydratase;
PDBTitle: crystal structure of apo d-serine deaminase from salmonella2 typhimurium
33c2o2jA_



not modelled 100.0 27 PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase beta chain;
PDBTitle: mycobacterium tuberculosis tryptophan synthase beta chain2 dimer (apoform)
34d1e5xa_



not modelled 100.0 19 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
35d1j0aa_



not modelled 100.0 16 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
36d1f2da_



not modelled 100.0 18 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
37d1tyza_



not modelled 100.0 18 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
38c3v7nA_



not modelled 100.0 17 PDB header:lyase
Chain: A: PDB Molecule:threonine synthase;
PDBTitle: crystal structure of threonine synthase (thrc) from from burkholderia2 thailandensis
39d1vb3a1



not modelled 100.0 17 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
40d1kl7a_



not modelled 100.0 16 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
41d1bg6a2



not modelled 92.4 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
42d1c1da1



not modelled 92.3 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
43d1o8ca2



not modelled 90.6 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
44c3iupB_



not modelled 89.9 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nadph:quinone oxidoreductase;
PDBTitle: crystal structure of putative nadph:quinone oxidoreductase2 (yp_296108.1) from ralstonia eutropha jmp134 at 1.70 a resolution
45d1vp8a_



not modelled 89.5 17 Fold:Pyruvate kinase C-terminal domain-like
Superfamily:PK C-terminal domain-like
Family:MTH1675-like
46d1o89a2



not modelled 89.2 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
47d1kola2



not modelled 87.2 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
48c3d4oA_



not modelled 86.1 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase subunit a;
PDBTitle: crystal structure of dipicolinate synthase subunit a (np_243269.1)2 from bacillus halodurans at 2.10 a resolution
49d1ml4a2



not modelled 81.5 17 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
50c3krtC_



not modelled 80.0 17 PDB header:oxidoreductase
Chain: C: PDB Molecule:crotonyl coa reductase;
PDBTitle: crystal structure of putative crotonyl coa reductase from streptomyces2 coelicolor a3(2)
51c3eywA_



not modelled 76.5 14 PDB header:transport protein
Chain: A: PDB Molecule:c-terminal domain of glutathione-regulated potassium-efflux
PDBTitle: crystal structure of the c-terminal domain of e. coli kefc in complex2 with keff
52d1tt7a2



not modelled 76.2 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
53d1l7da1



not modelled 74.5 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
54d1xa0a2



not modelled 71.3 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
55d1hyua1



not modelled 71.0 37 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
56c1ml4A_



not modelled 70.8 18 PDB header:transferase
Chain: A: PDB Molecule:aspartate transcarbamoylase;
PDBTitle: the pala-liganded aspartate transcarbamoylase catalytic subunit from2 pyrococcus abyssi
57d1fl2a1



not modelled 70.6 37 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
58c3p2yA_



not modelled 68.7 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:alanine dehydrogenase/pyridine nucleotide transhydrogenase;
PDBTitle: crystal structure of alanine dehydrogenase/pyridine nucleotide2 transhydrogenase from mycobacterium smegmatis
59c2vq3B_



not modelled 68.6 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:metalloreductase steap3;
PDBTitle: crystal structure of the membrane proximal oxidoreductase2 domain of human steap3, the dominant ferric reductase of3 the erythroid transferrin cycle
60d1trba1



not modelled 67.9 25 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
61c3s8mA_



not modelled 67.6 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-acp reductase;
PDBTitle: the crystal structure of fabv
62d1llua2



not modelled 67.4 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
63d1ekxa2



not modelled 66.9 21 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
64c3orqA_



not modelled 66.2 21 PDB header:ligase,biosynthetic protein
Chain: A: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide synthetase;
PDBTitle: crystal structure of n5-carboxyaminoimidazole synthetase from2 staphylococcus aureus complexed with adp
65c3grkE_



not modelled 65.3 13 PDB header:oxidoreductase
Chain: E: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of short chain dehydrogenase reductase2 sdr glucose-ribitol dehydrogenase from brucella melitensis
66c2bryA_



not modelled 64.9 24 PDB header:transport
Chain: A: PDB Molecule:nedd9 interacting protein with calponin homology
PDBTitle: crystal structure of the native monooxygenase domain of2 mical at 1.45 a resolution
67c2rgwD_



not modelled 64.6 13 PDB header:transferase
Chain: D: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: catalytic subunit of m. jannaschii aspartate2 transcarbamoylase
68d1cdoa2



not modelled 64.4 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
69c1m67A_



not modelled 63.7 9 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase;
PDBTitle: crystal structure of leishmania mexicana gpdh complexed with inhibitor2 2-bromo-6-hydroxy-purine
70c3o82A_



not modelled 63.6 11 PDB header:ligase
Chain: A: PDB Molecule:peptide arylation enzyme;
PDBTitle: structure of base n-terminal domain from acinetobacter baumannii bound2 to 5'-o-[n-(2,3-dihydroxybenzoyl)sulfamoyl] adenosine
71d1vdca1



not modelled 62.6 22 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
72d1bgva1



not modelled 60.8 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
73d1otha2



not modelled 60.6 19 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
74d1reoa1



not modelled 59.2 14 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD-linked reductases, N-terminal domain
75c2rirA_



not modelled 58.8 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase, a chain;
PDBTitle: crystal structure of dipicolinate synthase, a chain, from bacillus2 subtilis
76d2i0za1



not modelled 58.0 33 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:HI0933 N-terminal domain-like
77d1ykfa2



not modelled 57.8 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
78d1p0fa2



not modelled 57.8 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
79d1mv8a2



not modelled 56.0 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
80d3lada1



not modelled 56.0 26 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
81d1t57a_



not modelled 55.5 18 Fold:Pyruvate kinase C-terminal domain-like
Superfamily:PK C-terminal domain-like
Family:MTH1675-like
82c2bruB_



not modelled 54.7 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:nad(p) transhydrogenase subunit alpha;
PDBTitle: complex of the domain i and domain iii of escherichia coli2 transhydrogenase
83c2ywlA_



not modelled 54.1 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin reductase related protein;
PDBTitle: crystal structure of thioredoxin reductase-related protein ttha03702 from thermus thermophilus hb8
84c3allA_



not modelled 54.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase;
PDBTitle: crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid2 oxygenase, mutant y270a
85d1v9la1



not modelled 54.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
86d1pg5a2



not modelled 53.2 15 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
87c3r3sD_



not modelled 52.9 18 PDB header:oxidoreductase
Chain: D: PDB Molecule:oxidoreductase;
PDBTitle: structure of the ygha oxidoreductase from salmonella enterica
88d1ebda1



not modelled 52.8 22 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
89d2cula1



not modelled 52.6 33 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:GidA-like
90c2vhyB_



not modelled 52.4 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:alanine dehydrogenase;
PDBTitle: crystal structure of apo l-alanine dehydrogenase from2 mycobacterium tuberculosis
91c3pduF_



not modelled 52.2 20 PDB header:oxidoreductase
Chain: F: PDB Molecule:3-hydroxyisobutyrate dehydrogenase family protein;
PDBTitle: crystal structure of gamma-hydroxybutyrate dehydrogenase from2 geobacter sulfurreducens in complex with nadp+
92c2rghA_



not modelled 52.1 31 PDB header:oxidoreductase
Chain: A: PDB Molecule:alpha-glycerophosphate oxidase;
PDBTitle: structure of alpha-glycerophosphate oxidase from2 streptococcus sp.: a template for the mitochondrial alpha-3 glycerophosphate dehydrogenase
93d1rjwa2



not modelled 52.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
94d1tuga1



not modelled 51.7 22 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
95c2dplA_



not modelled 51.6 16 PDB header:ligase
Chain: A: PDB Molecule:gmp synthase [glutamine-hydrolyzing] subunit b;
PDBTitle: crystal structure of the gmp synthase from pyrococcus horikoshii ot3
96d1seza1



not modelled 50.4 17 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD-linked reductases, N-terminal domain
97d1ryia1



not modelled 50.4 22 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD-linked reductases, N-terminal domain
98c3a11D_



not modelled 50.1 19 PDB header:isomerase
Chain: D: PDB Molecule:translation initiation factor eif-2b, delta
PDBTitle: crystal structure of ribose-1,5-bisphosphate isomerase from2 thermococcus kodakaraensis kod1
99d1lvla1



not modelled 49.7 26 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
100c3tqiB_



not modelled 49.6 19 PDB header:ligase
Chain: B: PDB Molecule:gmp synthase [glutamine-hydrolyzing];
PDBTitle: structure of the gmp synthase (guaa) from coxiella burnetii
101d2gf3a1



not modelled 49.6 26 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD-linked reductases, N-terminal domain
102c2jb1B_



not modelled 49.2 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:l-amino acid oxidase;
PDBTitle: the l-amino acid oxidase from rhodococcus opacus in complex2 with l-alanine
103d1pvva2



not modelled 48.7 16 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
104d1d1ta2



not modelled 48.7 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
105c1hyuA_



not modelled 48.2 37 PDB header:oxidoreductase
Chain: A: PDB Molecule:alkyl hydroperoxide reductase subunit f;
PDBTitle: crystal structure of intact ahpf
106d1dxla1



not modelled 48.0 22 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
107c3cumA_



not modelled 47.6 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable 3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of a possible 3-hydroxyisobutyrate dehydrogenase2 from pseudomonas aeruginosa pao1
108d1neka2



not modelled 47.5 22 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
109c3ezsB_



not modelled 47.3 16 PDB header:transferase
Chain: B: PDB Molecule:aminotransferase aspb;
PDBTitle: crystal structure of aminotransferase aspb (np_207418.1) from2 helicobacter pylori 26695 at 2.19 a resolution
110c2q2qG_



not modelled 47.1 15 PDB header:oxidoreductase
Chain: G: PDB Molecule:beta-d-hydroxybutyrate dehydrogenase;
PDBTitle: structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida
111d1ojta1



not modelled 46.9 22 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
112d1u3wa2



not modelled 46.8 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
113c4a10A_



not modelled 46.5 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:octenoyl-coa reductase/carboxylase;
PDBTitle: apo-structure of 2-octenoyl-coa carboxylase reductase cinf from2 streptomyces sp.
114c1m6yA_



not modelled 46.2 17 PDB header:transferase
Chain: A: PDB Molecule:s-adenosyl-methyltransferase mraw;
PDBTitle: crystal structure analysis of tm0872, a putative sam-2 dependent methyltransferase, complexed with sah
115c3nrnA_



not modelled 45.9 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein pf1083;
PDBTitle: crystal structure of pf1083 protein from pyrococcus furiosus,2 northeast structural genomics consortium target pfr223
116d1lpfa1



not modelled 45.2 22 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
117c2qx7A_



not modelled 45.1 15 PDB header:plant protein
Chain: A: PDB Molecule:eugenol synthase 1;
PDBTitle: structure of eugenol synthase from ocimum basilicum
118c3ijrF_



not modelled 44.9 17 PDB header:oxidoreductase
Chain: F: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family;
PDBTitle: 2.05 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor' in complex3 with nad+
119d1e3ia2



not modelled 44.8 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
120c3o82B_



not modelled 44.6 11 PDB header:ligase
Chain: B: PDB Molecule:peptide arylation enzyme;
PDBTitle: structure of base n-terminal domain from acinetobacter baumannii bound2 to 5'-o-[n-(2,3-dihydroxybenzoyl)sulfamoyl] adenosine

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0