Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	D	I	I	G	G	Q	H	L	R	Q	M	W	D	D	L	A	D	V	Y	G	H	K	T	A	L	I	C	E	S	S	G	G	V	V	N	R	Y	S	Y	L	E	L	N	Q	E	I	N	R	T	A	N	L	F	Y	T	L	G	I	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		K	G	D	K	V	A	L	H	L	D	N	C	P	E	F	I	F	C	W	F	G	L	A	K	I	G	A	I	M	V	P	I	N	A	R	L	L	C	E	E	S	A	W	I	L	Q	N	S	Q	A	C	L	L	V	T	S	A	Q	F	Y
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	M	Y	Q	Q	I	Q	Q	E	D	A	T	Q	L	R	H	I	C	L	T	D	V	A	L	P	A	D	D	G	V	S	S	F	T	Q	L	K	N	Q	Q	P	A	T	L	C	Y	A	P	P	L	S	T	D	D	T	A	E	I	L	F
Secondary structure
SS confidence
Disorder																									?	?	?												?			?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	S	G	T	T	S	R	P	K	G	V	V	I	T	H	Y	N	L	R	F	A	G	Y	Y	S	A	W	Q	C	A	L	R	D	D	D	V	Y	L	T	V	M	P	A	F	H	I	D	C	Q	C	T	A	A	M	A	A	F	S	A	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	T	F	V	L	V	E	K	Y	S	A	R	A	F	W	G	Q	V	Q	K	Y	R	A	T	V	T	E	C	I	P	M	M	I	R	T	L	M	V	Q	P	P	S	A	N	D	Q	Q	H	R	L	R	E	V	M	F	Y	L	N	L	S
Secondary structure
SS confidence
Disorder																																																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		E	Q	E	K	D	A	F	C	E	R	F	G	V	R	L	L	T	S	Y	G	M	T	E	T	I	V	G	I	I	G	D	R	P	G	D	K	R	R	W	P	S	I	G	R	V	G	F	C	Y	E	A	E	I	R	D	D	H	N	R	P
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		L	P	A	G	E	I	G	E	I	C	I	K	G	I	P	G	K	T	I	F	K	E	Y	F	L	N	P	Q	A	T	A	K	V	L	E	A	D	G	W	L	H	T	G	D	T	G	Y	R	D	E	E	D	F	F	Y	F	V	D	R	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		C	N	M	I	K	R	G	G	E	N	V	S	C	V	E	L	E	N	I	I	A	A	H	P	K	I	Q	D	I	V	V	V	G	I	K	D	S	I	R	D	E	A	I	K	A	F	V	V	L	N	E	G	E	T	L	S	E	E	E	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.
Sequence		F	R	F	C	E	Q	N	M	A	K	F	K	V	P	S	Y	L	E	I	R	K	D	L	P	R	N	C	S	G	K	I	I	R	K	N	L	K
Secondary structure
SS confidence
Disorder																																?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1pg4 chain A Region: 8 - 517 Aligned: 509 Modelled: 510 Confidence: 100.0% Identity: 23% Fold: Acetyl-CoA synthetase-like Superfamily: Acetyl-CoA synthetase-like Family: Acetyl-CoA synthetase-like Phyre2 PDB 1ry2 chain A Region: 8 - 517 Aligned: 507 Modelled: 508 Confidence: 100.0% Identity: 19% Fold: Acetyl-CoA synthetase-like Superfamily: Acetyl-CoA synthetase-like Family: Acetyl-CoA synthetase-like Phyre2 PDB 2vsq chain A Region: 6 - 517 Aligned: 481 Modelled: 491 Confidence: 100.0% Identity: 22% PDB header:ligase Chain: A: PDB Molecule:surfactin synthetase subunit 3; PDBTitle: structure of surfactin a synthetase c (srfa-c), a2 nonribosomal peptide synthetase termination module Phyre2 PDB 3cw9 chain A domain 1 Region: 7 - 517 Aligned: 492 Modelled: 511 Confidence: 100.0% Identity: 24% Fold: Acetyl-CoA synthetase-like Superfamily: Acetyl-CoA synthetase-like Family: Acetyl-CoA synthetase-like Phyre2 PDB 1mdb chain A Region: 6 - 517 Aligned: 500 Modelled: 506 Confidence: 100.0% Identity: 21% Fold: Acetyl-CoA synthetase-like Superfamily: Acetyl-CoA synthetase-like Family: Acetyl-CoA synthetase-like Phyre2 PDB 3etc chain B Region: 8 - 505 Aligned: 496 Modelled: 498 Confidence: 100.0% Identity: 24% PDB header:ligase Chain: B: PDB Molecule:amp-binding protein; PDBTitle: 2.1 a structure of acyl-adenylate synthetase from methanosarcina2 acetivorans containing a link between lys256 and cys298 Phyre2 PDB 3eyn chain B Region: 1 - 517 Aligned: 508 Modelled: 517 Confidence: 100.0% Identity: 22% PDB header:ligase Chain: B: PDB Molecule:acyl-coenzyme a synthetase acsm2a; PDBTitle: crystal structure of human acyl-coa synthetase medium-chain2 family member 2a (l64p mutation) in a complex with coa Phyre2 PDB 3ni2 chain A Region: 1 - 517 Aligned: 507 Modelled: 510 Confidence: 100.0% Identity: 27% PDB header:ligase Chain: A: PDB Molecule:4-coumarate:coa ligase; PDBTitle: crystal structures and enzymatic mechanisms of a populus tomentosa 4-2 coumarate:coa ligase Phyre2 PDB 3e7w chain A Region: 8 - 517 Aligned: 482 Modelled: 490 Confidence: 100.0% Identity: 21% PDB header:ligase Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1; PDBTitle: crystal structure of dlta: implications for the reaction2 mechanism of non-ribosomal peptide synthetase (nrps)3 adenylation domains Phyre2 PDB 1amu chain A Region: 2 - 517 Aligned: 480 Modelled: 498 Confidence: 100.0% Identity: 19% Fold: Acetyl-CoA synthetase-like Superfamily: Acetyl-CoA synthetase-like Family: Acetyl-CoA synthetase-like Phyre2 PDB 2d1t chain A Region: 6 - 517 Aligned: 508 Modelled: 512 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:luciferin 4-monooxygenase; PDBTitle: crystal structure of the thermostable japanese firefly2 luciferase red-color emission s286n mutant complexed with3 high-energy intermediate analogue Phyre2 PDB 3ite chain B Region: 8 - 517 Aligned: 484 Modelled: 495 Confidence: 100.0% Identity: 18% PDB header:ligase Chain: B: PDB Molecule:sidn siderophore synthetase; PDBTitle: the third adenylation domain of the fungal sidn non-2 ribosomal peptide synthetase Phyre2 PDB 1amu chain B Region: 1 - 517 Aligned: 480 Modelled: 490 Confidence: 100.0% Identity: 18% PDB header:peptide synthetase Chain: B: PDB Molecule:gramicidin synthetase 1; PDBTitle: phenylalanine activating domain of gramicidin synthetase 12 in a complex with amp and phenylalanine Phyre2 PDB 1lci chain A Region: 4 - 517 Aligned: 500 Modelled: 514 Confidence: 100.0% Identity: 18% Fold: Acetyl-CoA synthetase-like Superfamily: Acetyl-CoA synthetase-like Family: Acetyl-CoA synthetase-like Phyre2 PDB 2v7b chain B Region: 8 - 517 Aligned: 480 Modelled: 495 Confidence: 100.0% Identity: 23% PDB header:ligase Chain: B: PDB Molecule:benzoate-coenzyme a ligase; PDBTitle: crystal structures of a benzoate coa ligase from2 burkholderia xenovorans lb400 Phyre2 PDB 3gqw chain B Region: 8 - 517 Aligned: 485 Modelled: 494 Confidence: 100.0% Identity: 19% PDB header:ligase Chain: B: PDB Molecule:fatty acid amp ligase; PDBTitle: crystal structure of a fatty acid amp ligase from e. coli with an acyl2 adenylate product bound Phyre2 PDB 3tsy chain A Region: 1 - 516 Aligned: 503 Modelled: 509 Confidence: 100.0% Identity: 24% PDB header:ligase, transferase Chain: A: PDB Molecule:fusion protein 4-coumarate--coa ligase 1, resveratrol PDBTitle: 4-coumaroyl-coa ligase::stilbene synthase fusion protein Phyre2 PDB 3kxw chain A Region: 2 - 517 Aligned: 496 Modelled: 497 Confidence: 100.0% Identity: 18% PDB header:ligase Chain: A: PDB Molecule:saframycin mx1 synthetase b; PDBTitle: the crystal structure of fatty acid amp ligase from legionella2 pneumophila Phyre2 PDB 1v25 chain A Region: 3 - 492 Aligned: 470 Modelled: 489 Confidence: 100.0% Identity: 24% Fold: Acetyl-CoA synthetase-like Superfamily: Acetyl-CoA synthetase-like Family: Acetyl-CoA synthetase-like Phyre2 PDB 3dhv chain A Region: 9 - 517 Aligned: 478 Modelled: 491 Confidence: 100.0% Identity: 20% PDB header:ligase Chain: A: PDB Molecule:d-alanine-poly(phosphoribitol) ligase; PDBTitle: crystal structure of dlta protein in complex with d-alanine2 adenylate Phyre2 1 d1pg4a_ 2 d1ry2a_ 3 c2vsqA_ 4 d3cw9a1 5 d1mdba_ 6 c3etcB_ 7 c3eynB_ 8 c3ni2A_ 9 c3e7wA_ 10 d1amua_ 11 c2d1tA_ 12 c3iteB_ 13 c1amuB_ 14 d1lcia_ 15 c2v7bB_ 16 c3gqwB_ 17 c3tsyA_ 18 c3kxwA_ 19 d1v25a_ 20 c3dhvA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1pg4a_ 100.0 23 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 2 d1ry2a_ 100.0 19 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 3 c2vsqA_ 100.0 22 PDB header:ligase Chain: A: PDB Molecule:surfactin synthetase subunit 3; PDBTitle: structure of surfactin a synthetase c (srfa-c), a2 nonribosomal peptide synthetase termination module 4 d3cw9a1 100.0 24 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 5 d1mdba_ 100.0 21 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 6 c3etcB_ 100.0 24 PDB header:ligase Chain: B: PDB Molecule:amp-binding protein; PDBTitle: 2.1 a structure of acyl-adenylate synthetase from methanosarcina2 acetivorans containing a link between lys256 and cys298 7 c3eynB_ 100.0 22 PDB header:ligase Chain: B: PDB Molecule:acyl-coenzyme a synthetase acsm2a; PDBTitle: crystal structure of human acyl-coa synthetase medium-chain2 family member 2a (l64p mutation) in a complex with coa 8 c3ni2A_ 100.0 27 PDB header:ligase Chain: A: PDB Molecule:4-coumarate:coa ligase; PDBTitle: crystal structures and enzymatic mechanisms of a populus tomentosa 4-2 coumarate:coa ligase 9 c3e7wA_ 100.0 21 PDB header:ligase Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1; PDBTitle: crystal structure of dlta: implications for the reaction2 mechanism of non-ribosomal peptide synthetase (nrps)3 adenylation domains 10 d1amua_ 100.0 19 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 11 c2d1tA_ 100.0 21 PDB header:oxidoreductase Chain: A: PDB Molecule:luciferin 4-monooxygenase; PDBTitle: crystal structure of the thermostable japanese firefly2 luciferase red-color emission s286n mutant complexed with3 high-energy intermediate analogue 12 c3iteB_ 100.0 18 PDB header:ligase Chain: B: PDB Molecule:sidn siderophore synthetase; PDBTitle: the third adenylation domain of the fungal sidn non-2 ribosomal peptide synthetase 13 c1amuB_ 100.0 18 PDB header:peptide synthetase Chain: B: PDB Molecule:gramicidin synthetase 1; PDBTitle: phenylalanine activating domain of gramicidin synthetase 12 in a complex with amp and phenylalanine 14 d1lcia_ 100.0 18 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 15 c2v7bB_ 100.0 23 PDB header:ligase Chain: B: PDB Molecule:benzoate-coenzyme a ligase; PDBTitle: crystal structures of a benzoate coa ligase from2 burkholderia xenovorans lb400 16 c3gqwB_ 100.0 19 PDB header:ligase Chain: B: PDB Molecule:fatty acid amp ligase; PDBTitle: crystal structure of a fatty acid amp ligase from e. coli with an acyl2 adenylate product bound 17 c3tsyA_ 100.0 24 PDB header:ligase, transferase Chain: A: PDB Molecule:fusion protein 4-coumarate--coa ligase 1, resveratrol PDBTitle: 4-coumaroyl-coa ligase::stilbene synthase fusion protein 18 c3kxwA_ 100.0 18 PDB header:ligase Chain: A: PDB Molecule:saframycin mx1 synthetase b; PDBTitle: the crystal structure of fatty acid amp ligase from legionella2 pneumophila 19 d1v25a_ 100.0 24 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 20 c3dhvA_ 100.0 20 PDB header:ligase Chain: A: PDB Molecule:d-alanine-poly(phosphoribitol) ligase; PDBTitle: crystal structure of dlta protein in complex with d-alanine2 adenylate 21 c3l8cA_ not modelled 100.0 16 PDB header:ligase Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1; PDBTitle: structure of probable d-alanine--poly(phosphoribitol) ligase2 subunit-1 from streptococcus pyogenes 22 c3nyrA_ not modelled 100.0 23 PDB header:ligase Chain: A: PDB Molecule:malonyl-coa ligase; PDBTitle: malonyl-coa ligase ternary product complex with malonyl-coa and amp2 bound 23 c3iplB_ not modelled 100.0 23 PDB header:ligase Chain: B: PDB Molecule:2-succinylbenzoate--coa ligase; PDBTitle: crystal structure of o-succinylbenzoic acid-coa ligase from2 staphylococcus aureus subsp. aureus mu50 24 c3g7sA_ not modelled 100.0 21 PDB header:ligase Chain: A: PDB Molecule:long-chain-fatty-acid--coa ligase (fadd-1); PDBTitle: crystal structure of a long-chain-fatty-acid-coa ligase2 (fadd1) from archaeoglobus fulgidus 25 c3o82B_ not modelled 100.0 21 PDB header:ligase Chain: B: PDB Molecule:peptide arylation enzyme; PDBTitle: structure of base n-terminal domain from acinetobacter baumannii bound2 to 5'-o-[n-(2,3-dihydroxybenzoyl)sulfamoyl] adenosine 26 c3o82A_ not modelled 100.0 21 PDB header:ligase Chain: A: PDB Molecule:peptide arylation enzyme; PDBTitle: structure of base n-terminal domain from acinetobacter baumannii bound2 to 5'-o-[n-(2,3-dihydroxybenzoyl)sulfamoyl] adenosine 27 c3ivrA_ not modelled 100.0 24 PDB header:ligase Chain: A: PDB Molecule:putative long-chain-fatty-acid coa ligase; PDBTitle: crystal structure of putative long-chain-fatty-acid coa ligase from2 rhodopseudomonas palustris cga009 28 c3e53A_ not modelled 100.0 22 PDB header:ligase Chain: A: PDB Molecule:fatty-acid-coa ligase fadd28; PDBTitle: crystal structure of n-terminal domain of a fatty acyl amp2 ligase faal28 from mycobacterium tuberculosis 29 c2y4oA_ not modelled 100.0 14 PDB header:ligase Chain: A: PDB Molecule:phenylacetate-coenzyme a ligase; PDBTitle: crystal structure of paak2 in complex with phenylacetyl adenylate 30 c2y27B_ not modelled 100.0 12 PDB header:ligase Chain: B: PDB Molecule:phenylacetate-coenzyme a ligase; PDBTitle: crystal structure of paak1 in complex with atp from2 burkholderia cenocepacia 31 c3qovD_ not modelled 100.0 14 PDB header:ligase Chain: D: PDB Molecule:phenylacetate-coenzyme a ligase; PDBTitle: crystal structure of a hypothetical acyl-coa ligase (bt_0428) from2 bacteroides thetaiotaomicron vpi-5482 at 2.20 a resolution 32 c3hguB_ not modelled 99.6 12 PDB header:biosynthetic protein Chain: B: PDB Molecule:ehpf; PDBTitle: structure of phenazine antibiotic biosynthesis protein 33 c3laxA_ not modelled 99.6 12 PDB header:ligase Chain: A: PDB Molecule:phenylacetate-coenzyme a ligase; PDBTitle: the crystal structure of a domain of phenylacetate-coenzyme2 a ligase from bacteroides vulgatus atcc 8482 34 d2ayia1 not modelled 82.8 20 Fold:Thermophilic metalloprotease-like Superfamily:Thermophilic metalloprotease-like Family:Thermophilic metalloprotease (M29) 35 d1pl8a2 not modelled 68.1 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 36 c3smaD_ not modelled 62.3 23 PDB header:transferase Chain: D: PDB Molecule:frbf; PDBTitle: a new n-acetyltransferase fold in the structure and mechanism of the2 phosphonate biosynthetic enzyme frbf 37 c3ippA_ not modelled 52.2 8 PDB header:transferase Chain: A: PDB Molecule:putative thiosulfate sulfurtransferase ynje; PDBTitle: crystal structure of sulfur-free ynje 38 d1piwa2 not modelled 51.5 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 39 c1uarA_ not modelled 49.3 15 PDB header:transferase Chain: A: PDB Molecule:rhodanese; PDBTitle: crystal structure of rhodanese from thermus thermophilus hb8 40 d1ykfa2 not modelled 49.2 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 41 d2nyga1 not modelled 47.7 23 Fold:TTHA0583/YokD-like Superfamily:TTHA0583/YokD-like Family:Aminoglycoside 3-N-acetyltransferase-like 42 c3e4fB_ not modelled 47.3 23 PDB header:transferase Chain: B: PDB Molecule:aminoglycoside n3-acetyltransferase; PDBTitle: crystal structure of ba2930- a putative aminoglycoside n3-2 acetyltransferase from bacillus anthracis 43 d1rjwa2 not modelled 44.6 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 44 d1llua2 not modelled 42.9 9 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 45 d1iz0a2 not modelled 42.0 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 46 c3olhA_ not modelled 39.9 10 PDB header:transferase Chain: A: PDB Molecule:3-mercaptopyruvate sulfurtransferase; PDBTitle: human 3-mercaptopyruvate sulfurtransferase 47 c1vs3B_ not modelled 37.0 12 PDB header:isomerase Chain: B: PDB Molecule:trna pseudouridine synthase a; PDBTitle: crystal structure of the trna pseudouridine synthase trua from thermus2 thermophilus hb8 48 c3bcxA_ not modelled 36.7 20 PDB header:transferase Chain: A: PDB Molecule:cdp-6-deoxy-l-threo-d-glycero-4-hexulose-3- PDBTitle: e1 dehydrase 49 c2ywiA_ not modelled 34.3 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical conserved protein; PDBTitle: crystal structure of uncharacterized conserved protein from2 geobacillus kaustophilus 50 d1jvba2 not modelled 34.3 3 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 51 d1e3ja2 not modelled 33.8 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 52 d1z7wa1 not modelled 33.5 16 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 53 d1i1ga2 not modelled 33.3 14 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Lrp/AsnC-like transcriptional regulator C-terminal domain 54 d1f06a2 not modelled 33.0 21 Fold:FwdE/GAPDH domain-like Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family:Dihydrodipicolinate reductase-like 55 d1d1ta2 not modelled 32.7 8 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 56 d1kola2 not modelled 32.7 8 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 57 d1uaaa2 not modelled 27.8 10 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 58 d1zjca1 not modelled 27.6 12 Fold:Thermophilic metalloprotease-like Superfamily:Thermophilic metalloprotease-like Family:Thermophilic metalloprotease (M29) 59 c2zy3A_ not modelled 27.1 11 PDB header:lyase Chain: A: PDB Molecule:l-aspartate beta-decarboxylase; PDBTitle: dodecameric l-aspartate beta-decarboxylase 60 c3aaxB_ not modelled 25.4 18 PDB header:transferase Chain: B: PDB Molecule:putative thiosulfate sulfurtransferase; PDBTitle: crystal structure of probable thiosulfate sulfurtransferase2 cysa3 (rv3117) from mycobacterium tuberculosis: monoclinic3 form 61 d1e3ia2 not modelled 24.2 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 62 d1uara2 not modelled 24.1 15 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 63 d1uufa2 not modelled 22.5 9 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 64 d1qora2 not modelled 22.4 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 65 d1jqba2 not modelled 21.6 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 66 d1p0fa2 not modelled 21.5 8 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 67 d1yb5a2 not modelled 20.5 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 68 c2zbcH_ not modelled 20.3 17 PDB header:transcription Chain: H: PDB Molecule:83aa long hypothetical transcriptional regulator asnc; PDBTitle: crystal structure of sts042, a stand-alone ram module protein, from2 hyperthermophilic archaeon sulfolobus tokodaii strain7. 69 d2idba2 not modelled 20.0 13 Fold:UbiD C-terminal domain-like Superfamily:UbiD C-terminal domain-like Family:UbiD C-terminal domain-like 70 c2jkzB_ not modelled 19.7 16 PDB header:transferase Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: saccharomyces cerevisiae hypoxanthine-guanine2 phosphoribosyltransferase in complex with gmp (guanosine 5'3 -monophosphate) (orthorhombic crystal form) 71 c1c4kA_ not modelled 19.1 14 PDB header:lyase Chain: A: PDB Molecule:protein (ornithine decarboxylase); PDBTitle: ornithine decarboxylase mutant (gly121tyr) 72 c3s99A_ not modelled 19.1 8 PDB header:lipid binding protein Chain: A: PDB Molecule:basic membrane lipoprotein; PDBTitle: crystal structure of a basic membrane lipoprotein from brucella2 melitensis, iodide soak 73 d2cfxa2 not modelled 19.0 17 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Lrp/AsnC-like transcriptional regulator C-terminal domain 74 d1okga1 not modelled 18.4 20 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 75 c2gn0A_ not modelled 17.1 9 PDB header:lyase Chain: A: PDB Molecule:threonine dehydratase catabolic; PDBTitle: crystal structure of dimeric biodegradative threonine deaminase (tdcb)2 from salmonella typhimurium at 1.7 a resolution (triclinic form with3 one complete subunit built in alternate conformation) 76 d2fzwa2 not modelled 16.9 7 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 77 d2cg4a2 not modelled 16.7 6 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Lrp/AsnC-like transcriptional regulator C-terminal domain 78 d1nula_ not modelled 16.5 4 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 79 c1ydnA_ not modelled 16.4 13 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35. 80 d1ja1a1 not modelled 16.2 21 Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:NADPH-cytochrome p450 reductase FAD-binding domain-like 81 c2djwF_ not modelled 15.7 22 PDB header:unknown function Chain: F: PDB Molecule:probable transcriptional regulator, asnc family; PDBTitle: crystal structure of ttha0845 from thermus thermophilus hb8 82 d1f20a1 not modelled 15.6 11 Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:NADPH-cytochrome p450 reductase FAD-binding domain-like 83 c2e1aD_ not modelled 15.5 16 PDB header:transcription Chain: D: PDB Molecule:75aa long hypothetical regulatory protein asnc; PDBTitle: crystal structure of ffrp-dm1 84 d1udxa3 not modelled 15.2 25 Fold:Obg GTP-binding protein C-terminal domain Superfamily:Obg GTP-binding protein C-terminal domain Family:Obg GTP-binding protein C-terminal domain 85 c3hzuA_ not modelled 15.2 17 PDB header:transferase Chain: A: PDB Molecule:thiosulfate sulfurtransferase ssea; PDBTitle: crystal structure of probable thiosulfate sulfurtransferase ssea2 (rhodanese) from mycobacterium tuberculosis 86 c3n75E_ not modelled 15.1 10 PDB header:lyase Chain: E: PDB Molecule:lysine decarboxylase, inducible; PDBTitle: x-ray crystal structure of the escherichia coli inducible lysine2 decarboxylase ldci 87 c3hjtB_ not modelled 15.1 9 PDB header:cell adhesion, transport protein Chain: B: PDB Molecule:lmb; PDBTitle: structure of laminin binding protein (lmb) of streptococcus2 agalactiae a bifunctional protein with adhesin and metal3 transporting activity 88 c1yj7A_ not modelled 14.0 14 PDB header:protein transport Chain: A: PDB Molecule:escj; PDBTitle: crystal structure of enteropathogenic e.coli (epec) type iii secretion2 system protein escj 89 c1okgA_ not modelled 13.6 20 PDB header:transferase Chain: A: PDB Molecule:possible 3-mercaptopyruvate sulfurtransferase; PDBTitle: 3-mercaptopyruvate sulfurtransferase from leishmania major 90 c1e0cA_ not modelled 13.5 16 PDB header:sulfurtransferase Chain: A: PDB Molecule:sulfurtransferase; PDBTitle: sulfurtransferase from azotobacter vinelandii 91 c2jwlB_ not modelled 13.4 19 PDB header:membrane protein Chain: B: PDB Molecule:protein tolr; PDBTitle: solution structure of periplasmic domain of tolr from h.2 influenzae with saxs data 92 c3iauA_ not modelled 13.4 6 PDB header:lyase Chain: A: PDB Molecule:threonine deaminase; PDBTitle: the structure of the processed form of threonine deaminase isoform 22 from solanum lycopersicum 93 d1l9xa_ not modelled 13.4 21 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 94 c1l9xA_ not modelled 13.4 21 PDB header:hydrolase Chain: A: PDB Molecule:gamma-glutamyl hydrolase; PDBTitle: structure of gamma-glutamyl hydrolase 95 d1pwha_ not modelled 13.4 11 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 96 d2jhfa2 not modelled 13.3 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 97 d1u3wa2 not modelled 12.7 8 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 98 d1liua3 not modelled 12.4 17 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:Pyruvate kinase, C-terminal domain 99 d1wkva1 not modelled 12.4 10 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0