Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	N	S	R	I	P	G	E	H	F	F	T	T	S	D	N	T	A	L	F	Y	R	H	W	P	A	L	Q	P	G	A	K	K	V	I	V	L	F	H	R	G	H	E	H	S	G	R	L	Q	H	L	V	D	E	L	A	M	P	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	A	F	Y	A	W	D	A	R	G	H	G	K	S	S	G	P	R	G	Y	S	P	S	L	A	R	S	V	R	D	V	D	E	F	V	R	F	A	A	S	D	S	Q	V	G	L	E	E	V	V	V	I	A	Q	S	V	G	A	V	L
Secondary structure
SS confidence
Disorder																			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	A	T	W	I	H	D	Y	A	P	A	I	R	G	L	V	L	A	S	P	A	F	K	V	K	L	Y	V	P	L	A	R	P	A	L	A	L	W	H	R	L	R	G	L	F	F	I	N	S	Y	V	K	G	R	Y	L	T	H	D	R
Secondary structure
SS confidence
Disorder																								?	?	?	?															?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	R	G	A	S	F	N	N	D	P	L	I	T	R	A	I	A	V	N	I	L	L	D	L	Y	K	T	S	E	R	I	I	R	D	A	A	A	I	T	L	P	T	Q	L	L	I	S	G	D	D	Y	V	V	H	R	Q	P	Q	I	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		F	Y	Q	R	L	R	S	P	L	K	E	L	H	L	L	P	G	F	Y	H	D	T	L	G	E	E	N	R	A	L	A	F	E	K	M	Q	S	F	I	S	R	L	Y	A	N	K	S	Q	K	F	D	Y	Q	H	E	D	C	T	G	P
Secondary structure
SS confidence
Disorder																																													?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		S	A	D	R	W	R	L	L	S	G	G	P	V	P	L	S	P	V	D	L	A	Y	R	F	M	R	K	A	M	K	L	F	G	T	H	S	S	G	L	H	L	G	M	S	T	G	F	D	S	G	S	S	L	D	Y	V	Y	Q	N	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?		?	?	?																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		P	Q	G	S	N	A	F	G	R	L	V	D	K	I	Y	L	N	S	V	G	W	R	G	I	R	Q	R	K	T	H	L	Q	I	L	I	K	Q	A	V	A	D	L	H	A	K	G	L	A	V	R	V	V	D	I	A	A	G	H	G	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?																																				?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		Y	V	L	D	A	L	A	N	E	P	A	V	S	D	I	L	L	R	D	Y	S	E	L	N	V	A	Q	G	Q	E	M	I	A	Q	R	G	M	S	G	R	V	R	F	E	Q	G	D	A	F	N	P	E	E	L	S	A	L	T	P	R
Secondary structure
SS confidence
Disorder																																				?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		P	T	L	A	I	V	S	G	L	Y	E	L	F	P	E	N	E	Q	V	K	N	S	L	A	G	L	A	N	A	I	E	P	G	G	I	L	I	Y	T	G	Q	P	W	H	P	Q	L	E	M	I	A	G	V	L	T	S	H	K	D	G
Secondary structure
SS confidence
Disorder																															?			?																					?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.
Sequence		K	P	W	V	M	R	V	R	S	Q	G	E	M	D	S	L	V	R	D	A	G	F	D	K	C	T	Q	R	I	D	E	W	G	I	F	T	V	S	M	A	V	R	R	D	N
Secondary structure
SS confidence
Disorder																																										?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3jw8 chain A Region: 2 - 284 Aligned: 280 Modelled: 283 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:mgll protein; PDBTitle: crystal structure of human mono-glyceride lipase Phyre2 PDB 3hju chain B Region: 2 - 285 Aligned: 281 Modelled: 284 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: B: PDB Molecule:monoglyceride lipase; PDBTitle: crystal structure of human monoglyceride lipase Phyre2 PDB 1k8q chain A Region: 8 - 281 Aligned: 269 Modelled: 274 Confidence: 100.0% Identity: 17% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Gastric lipase Phyre2 PDB 1hlg chain A Region: 8 - 281 Aligned: 269 Modelled: 274 Confidence: 100.0% Identity: 17% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Gastric lipase Phyre2 PDB 1cr6 chain A Region: 10 - 281 Aligned: 258 Modelled: 258 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase; PDBTitle: crystal structure of murine soluble epoxide hydrolase2 complexed with cpu inhibitor Phyre2 PDB 2vav chain L Region: 1 - 281 Aligned: 272 Modelled: 281 Confidence: 100.0% Identity: 13% PDB header:transferase Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak) Phyre2 PDB 2y6v chain B Region: 1 - 294 Aligned: 277 Modelled: 294 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:peroxisomal membrane protein lpx1; PDBTitle: peroxisomal alpha-beta-hydrolase lpx1 (yor084w) from2 saccharomyces cerevisiae (crystal form i) Phyre2 PDB 2vat chain A domain 1 Region: 1 - 281 Aligned: 272 Modelled: 281 Confidence: 100.0% Identity: 15% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: O-acetyltransferase Phyre2 PDB 3i1i chain A Region: 12 - 285 Aligned: 267 Modelled: 274 Confidence: 100.0% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:homoserine o-acetyltransferase; PDBTitle: x-ray crystal structure of homoserine o-acetyltransferase from2 bacillus anthracis Phyre2 PDB 2b61 chain A domain 1 Region: 1 - 281 Aligned: 274 Modelled: 281 Confidence: 100.0% Identity: 13% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: O-acetyltransferase Phyre2 PDB 2jbw chain B Region: 1 - 284 Aligned: 246 Modelled: 253 Confidence: 100.0% Identity: 10% PDB header:hydrolase Chain: B: PDB Molecule:2,6-dihydroxy-pseudo-oxynicotine hydrolase; PDBTitle: crystal structure of the 2,6-dihydroxy-pseudo-oxynicotine2 hydrolase. Phyre2 PDB 2hu7 chain A Region: 7 - 283 Aligned: 239 Modelled: 241 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:acylamino-acid-releasing enzyme; PDBTitle: binding of inhibitors by acylaminoacyl peptidase Phyre2 PDB 2jbw chain A domain 1 Region: 1 - 284 Aligned: 246 Modelled: 253 Confidence: 100.0% Identity: 10% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: 2,6-dihydropseudooxynicotine hydrolase-like Phyre2 PDB 2e3j chain A Region: 10 - 284 Aligned: 266 Modelled: 275 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase ephb; PDBTitle: the crystal structure of epoxide hydrolase b (rv1938) from2 mycobacterium tuberculosis at 2.1 angstrom Phyre2 PDB 2q0x chain A Region: 3 - 282 Aligned: 272 Modelled: 280 Confidence: 100.0% Identity: 13% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: alpha/beta hydrolase fold protein of unknown function Phyre2 PDB 2cjp chain A Region: 9 - 281 Aligned: 266 Modelled: 273 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase; PDBTitle: structure of potato (solanum tuberosum) epoxide hydrolase i2 (steh1) Phyre2 PDB 1b6g chain A Region: 7 - 281 Aligned: 265 Modelled: 273 Confidence: 100.0% Identity: 14% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Haloalkane dehalogenase Phyre2 PDB 2pl5 chain A domain 1 Region: 16 - 281 Aligned: 259 Modelled: 266 Confidence: 100.0% Identity: 15% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: O-acetyltransferase Phyre2 PDB 2wtm chain C Region: 10 - 284 Aligned: 245 Modelled: 255 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: C: PDB Molecule:est1e; PDBTitle: est1e from butyrivibrio proteoclasticus Phyre2 PDB 3om8 chain A Region: 8 - 279 Aligned: 257 Modelled: 266 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:probable hydrolase; PDBTitle: the crystal structure of a hydrolase from pseudomonas aeruginosa pa01 Phyre2 PDB 3ocj chain A Region: 379 - 583 Aligned: 194 Modelled: 193 Confidence: 99.9% Identity: 18% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative exported protein; PDBTitle: the crystal structure of a possilbe exported protein from bordetella2 parapertussis Phyre2 PDB 1im8 chain A Region: 389 - 582 Aligned: 185 Modelled: 180 Confidence: 99.9% Identity: 17% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: Hypothetical protein HI0319 (YecO) Phyre2 PDB 2gh1 chain A domain 1 Region: 392 - 571 Aligned: 171 Modelled: 166 Confidence: 99.9% Identity: 18% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: BC2162-like Phyre2 PDB 3gwz chain B Region: 370 - 582 Aligned: 204 Modelled: 201 Confidence: 99.9% Identity: 15% PDB header:transferase Chain: B: PDB Molecule:mmcr; PDBTitle: structure of the mitomycin 7-o-methyltransferase mmcr Phyre2 PDB 3dlc chain A Region: 390 - 578 Aligned: 179 Modelled: 177 Confidence: 99.9% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:putative s-adenosyl-l-methionine-dependent PDBTitle: crystal structure of a putative s-adenosyl-l-methionine-dependent2 methyltransferase (mmp1179) from methanococcus maripaludis at 1.15 a3 resolution Phyre2 PDB 3bkx chain B Region: 388 - 568 Aligned: 178 Modelled: 175 Confidence: 99.9% Identity: 9% PDB header:transferase Chain: B: PDB Molecule:sam-dependent methyltransferase; PDBTitle: crystal structure of cyclopropane-fatty-acyl-phospholipid synthase-2 like protein (yp_807781.1) from lactobacillus casei atcc 334 at 1.853 a resolution Phyre2 1 c3jw8A_ 2 c3hjuB_ 3 d1k8qa_ 4 d1hlga_ 5 c1cr6A_ 6 c2vavL_ 7 c2y6vB_ 8 d2vata1 9 c3i1iA_ 10 d2b61a1 11 c2jbwB_ 12 c2hu7A_ 13 d2jbwa1 14 c2e3jA_ 15 c2q0xA_ 16 c2cjpA_ 17 d1b6ga_ 18 d2pl5a1 19 c2wtmC_ 20 c3om8A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 c3ocjA_ 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 d1im8a_ 123 124 125 126 127 128 129 130 131 d2gh1a1 132 c3gwzB_ 133 134 c3dlcA_ 135 136 137 138 139 c3bkxB_ 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499