Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP42907
DateThu Jan 5 12:02:05 GMT 2012
Unique Job ID666cce4505a31e52

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3odpA_
Top template information
PDB header:isomerase
Chain: A: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase;
PDBTitle: crystal structure of a putative tagatose-6-phosphate ketose/aldose2 isomerase (nt01cx_0292) from clostridium novyi nt at 2.35 a3 resolution
Confidence and coverage
Confidence:100.0% Coverage: 98%
378 residues ( 98% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MPENYTPAAAATGTWTEEEIRHQPRAWIRSLTNIDALRSALNNFLEPLLRKENLRIILTG
Secondary structure 

















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Disorder  ???????




















































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   .........70.........80.........90.........100.........110.........120
Sequence  AGTSAFIGDIIAPWLASHTGKNFSAVPTTDLVTNPMDYLNPAHPLLLISFGRSGNSPESV
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   .........130.........140.........150.........160.........170.........180
Sequence  AAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFALLMPAETHDRGFAMTSSITTMM
Secondary structure 























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Disorder 





















?




































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   .........190.........200.........210.........220.........230.........240
Sequence  ASCLAVFAPETINSQTFRDVADRCQAILTSLGDFSEGVFGYAPWKRIVYLGSGGLQGAAR
Secondary structure 
















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?















































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   .........250.........260.........270.........280.........290.........300
Sequence  ESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDDETLVVVFVSSHPYTRQYDLDLLAELR
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   .........310.........320.........330.........340.........350.........360
Sequence  RDNQAMRVIAIAAESSDIVAAGPHIILPPSRHFIDVEQAFCFLMYAQTFALMQSLHMGNT
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   .........370.........380....
Sequence  PDTPSASGTVNRVVQGVIIHPWQA
Secondary structure 












SS confidence 























Disorder 



















????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3odp chain A

3D model

Region: 4 - 382
Aligned: 378
Modelled: 379
Confidence: 100.0%
Identity: 40%
PDB header:isomerase
Chain: A: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase;
PDBTitle: crystal structure of a putative tagatose-6-phosphate ketose/aldose2 isomerase (nt01cx_0292) from clostridium novyi nt at 2.35 a3 resolution

Phyre2

PDB 3c3j chain A

3D model

Region: 4 - 384
Aligned: 370
Modelled: 381
Confidence: 100.0%
Identity: 98%
PDB header:isomerase
Chain: A: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase;
PDBTitle: crystal structure of tagatose-6-phosphate ketose/aldose isomerase from2 escherichia coli

Phyre2

PDB 3i0z chain B

3D model

Region: 4 - 383
Aligned: 377
Modelled: 380
Confidence: 100.0%
Identity: 42%
PDB header:isomerase
Chain: B: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase;
PDBTitle: crystal structure of putative putative tagatose-6-phosphate2 ketose/aldose isomerase (np_344614.1) from streptococcus pneumoniae3 tigr4 at 1.70 a resolution

Phyre2

PDB 1jxa chain A

3D model

Region: 4 - 374
Aligned: 351
Modelled: 371
Confidence: 100.0%
Identity: 21%
PDB header:transferase
Chain: A: PDB Molecule:glucosamine 6-phosphate synthase;
PDBTitle: glucosamine 6-phosphate synthase with glucose 6-phosphate

Phyre2

PDB 2zj3 chain A

3D model

Region: 9 - 374
Aligned: 344
Modelled: 363
Confidence: 100.0%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:glucosamine--fructose-6-phosphate
PDBTitle: isomerase domain of human glucose:fructose-6-phosphate2 amidotransferase

Phyre2

PDB 2aml chain B

3D model

Region: 16 - 366
Aligned: 326
Modelled: 337
Confidence: 100.0%
Identity: 14%
PDB header:transferase
Chain: B: PDB Molecule:sis domain protein;
PDBTitle: crystal structure of lmo0035 protein (46906266) from listeria2 monocytogenes 4b f2365 at 1.50 a resolution

Phyre2

PDB 1moq chain A

3D model

Region: 10 - 375
Aligned: 347
Modelled: 363
Confidence: 100.0%
Identity: 20%
Fold: SIS domain
Superfamily: SIS domain
Family: double-SIS domain

Phyre2

PDB 3tbf chain A

3D model

Region: 11 - 364
Aligned: 339
Modelled: 354
Confidence: 100.0%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:glucosamine--fructose-6-phosphate aminotransferase
PDBTitle: c-terminal domain of glucosamine-fructose-6-phosphate aminotransferase2 from francisella tularensis.

Phyre2

PDB 3fj1 chain A

3D model

Region: 9 - 362
Aligned: 328
Modelled: 353
Confidence: 100.0%
Identity: 18%
PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerase;
PDBTitle: crystal structure of putative phosphosugar isomerase (yp_167080.1)2 from silicibacter pomeroyi dss-3 at 1.75 a resolution

Phyre2

PDB 3g68 chain A

3D model

Region: 13 - 373
Aligned: 332
Modelled: 356
Confidence: 100.0%
Identity: 16%
PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerase;
PDBTitle: crystal structure of a putative phosphosugar isomerase (cd3275) from2 clostridium difficile 630 at 1.80 a resolution

Phyre2

PDB 2dec chain A

3D model

Region: 16 - 375
Aligned: 321
Modelled: 349
Confidence: 100.0%
Identity: 23%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:325aa long hypothetical protein;
PDBTitle: crystal structure of the ph0510 protein from pyrococcus horikoshii ot3

Phyre2

PDB 1j5x chain A

3D model

Region: 14 - 374
Aligned: 316
Modelled: 333
Confidence: 100.0%
Identity: 22%
Fold: SIS domain
Superfamily: SIS domain
Family: double-SIS domain

Phyre2

PDB 2a3n chain A

3D model

Region: 21 - 371
Aligned: 327
Modelled: 351
Confidence: 100.0%
Identity: 15%
PDB header:sugar binding protein
Chain: A: PDB Molecule:putative glucosamine-fructose-6-phosphate aminotransferase;
PDBTitle: crystal structure of a putative glucosamine-fructose-6-phosphate2 aminotransferase (stm4540.s) from salmonella typhimurium lt2 at 1.353 a resolution

Phyre2

PDB 3eua chain D

3D model

Region: 38 - 370
Aligned: 310
Modelled: 333
Confidence: 100.0%
Identity: 15%
PDB header:isomerase
Chain: D: PDB Molecule:putative fructose-aminoacid-6-phosphate deglycase;
PDBTitle: crystal structure of a putative phosphosugar isomerase (bsu32610) from2 bacillus subtilis at 1.90 a resolution

Phyre2

PDB 2puw chain A

3D model

Region: 12 - 362
Aligned: 322
Modelled: 341
Confidence: 100.0%
Identity: 15%
PDB header:transferase
Chain: A: PDB Molecule:isomerase domain of glutamine-fructose-6-phosphate
PDBTitle: the crystal structure of isomerase domain of glucosamine-6-phosphate2 synthase from candida albicans

Phyre2

PDB 3fkj chain A

3D model

Region: 37 - 371
Aligned: 312
Modelled: 329
Confidence: 100.0%
Identity: 17%
PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerases;
PDBTitle: crystal structure of a putative phosphosugar isomerase (stm_0572) from2 salmonella typhimurium lt2 at 2.12 a resolution

Phyre2

PDB 3knz chain A

3D model

Region: 14 - 353
Aligned: 314
Modelled: 340
Confidence: 100.0%
Identity: 17%
PDB header:sugar binding protein
Chain: A: PDB Molecule:putative sugar binding protein;
PDBTitle: crystal structure of putative sugar binding protein (np_459565.1) from2 salmonella typhimurium lt2 at 2.50 a resolution

Phyre2

PDB 3hba chain A

3D model

Region: 11 - 363
Aligned: 309
Modelled: 338
Confidence: 100.0%
Identity: 20%
PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerase;
PDBTitle: crystal structure of a putative phosphosugar isomerase (sden_2705)2 from shewanella denitrificans os217 at 2.00 a resolution

Phyre2

PDB 1x9i chain A

3D model

Region: 51 - 373
Aligned: 263
Modelled: 287
Confidence: 100.0%
Identity: 17%
Fold: SIS domain
Superfamily: SIS domain
Family: double-SIS domain

Phyre2

PDB 2xhz chain C

3D model

Region: 16 - 187
Aligned: 157
Modelled: 172
Confidence: 99.8%
Identity: 20%
PDB header:isomerase
Chain: C: PDB Molecule:arabinose 5-phosphate isomerase;
PDBTitle: probing the active site of the sugar isomerase domain from e. coli2 arabinose-5-phosphate isomerase via x-ray crystallography

Phyre2
1

c3odpA_
2

c3c3jA_
3

c3i0zB_
4

c1jxaA_
5

c2zj3A_
6

c2amlB_
7

d1moqa_
8

c3tbfA_
9

c3fj1A_
10

c3g68A_
11

c2decA_
12

d1j5xa_
13

c2a3nA_
14

c3euaD_
15

c2puwA_
16

c3fkjA_
17

c3knzA_
18

c3hbaA_
19

d1x9ia_
20

c2xhzC_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3odpA_



100.0 40 PDB header:isomerase
Chain: A: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase;
PDBTitle: crystal structure of a putative tagatose-6-phosphate ketose/aldose2 isomerase (nt01cx_0292) from clostridium novyi nt at 2.35 a3 resolution
2c3c3jA_



100.0 98 PDB header:isomerase
Chain: A: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase;
PDBTitle: crystal structure of tagatose-6-phosphate ketose/aldose isomerase from2 escherichia coli
3c3i0zB_



100.0 42 PDB header:isomerase
Chain: B: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase;
PDBTitle: crystal structure of putative putative tagatose-6-phosphate2 ketose/aldose isomerase (np_344614.1) from streptococcus pneumoniae3 tigr4 at 1.70 a resolution
4c1jxaA_



100.0 21 PDB header:transferase
Chain: A: PDB Molecule:glucosamine 6-phosphate synthase;
PDBTitle: glucosamine 6-phosphate synthase with glucose 6-phosphate
5c2zj3A_



100.0 17 PDB header:transferase
Chain: A: PDB Molecule:glucosamine--fructose-6-phosphate
PDBTitle: isomerase domain of human glucose:fructose-6-phosphate2 amidotransferase
6c2amlB_



100.0 14 PDB header:transferase
Chain: B: PDB Molecule:sis domain protein;
PDBTitle: crystal structure of lmo0035 protein (46906266) from listeria2 monocytogenes 4b f2365 at 1.50 a resolution
7d1moqa_



100.0 20 Fold:SIS domain
Superfamily:SIS domain
Family:double-SIS domain
8c3tbfA_



100.0 17 PDB header:transferase
Chain: A: PDB Molecule:glucosamine--fructose-6-phosphate aminotransferase
PDBTitle: c-terminal domain of glucosamine-fructose-6-phosphate aminotransferase2 from francisella tularensis.
9c3fj1A_



100.0 18 PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerase;
PDBTitle: crystal structure of putative phosphosugar isomerase (yp_167080.1)2 from silicibacter pomeroyi dss-3 at 1.75 a resolution
10c3g68A_



100.0 16 PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerase;
PDBTitle: crystal structure of a putative phosphosugar isomerase (cd3275) from2 clostridium difficile 630 at 1.80 a resolution
11c2decA_



100.0 23 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:325aa long hypothetical protein;
PDBTitle: crystal structure of the ph0510 protein from pyrococcus horikoshii ot3
12d1j5xa_



100.0 22 Fold:SIS domain
Superfamily:SIS domain
Family:double-SIS domain
13c2a3nA_



100.0 15 PDB header:sugar binding protein
Chain: A: PDB Molecule:putative glucosamine-fructose-6-phosphate aminotransferase;
PDBTitle: crystal structure of a putative glucosamine-fructose-6-phosphate2 aminotransferase (stm4540.s) from salmonella typhimurium lt2 at 1.353 a resolution
14c3euaD_



100.0 15 PDB header:isomerase
Chain: D: PDB Molecule:putative fructose-aminoacid-6-phosphate deglycase;
PDBTitle: crystal structure of a putative phosphosugar isomerase (bsu32610) from2 bacillus subtilis at 1.90 a resolution
15c2puwA_



100.0 15 PDB header:transferase
Chain: A: PDB Molecule:isomerase domain of glutamine-fructose-6-phosphate
PDBTitle: the crystal structure of isomerase domain of glucosamine-6-phosphate2 synthase from candida albicans
16c3fkjA_



100.0 17 PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerases;
PDBTitle: crystal structure of a putative phosphosugar isomerase (stm_0572) from2 salmonella typhimurium lt2 at 2.12 a resolution
17c3knzA_



100.0 17 PDB header:sugar binding protein
Chain: A: PDB Molecule:putative sugar binding protein;
PDBTitle: crystal structure of putative sugar binding protein (np_459565.1) from2 salmonella typhimurium lt2 at 2.50 a resolution
18c3hbaA_



100.0 20 PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerase;
PDBTitle: crystal structure of a putative phosphosugar isomerase (sden_2705)2 from shewanella denitrificans os217 at 2.00 a resolution
19d1x9ia_



100.0 17 Fold:SIS domain
Superfamily:SIS domain
Family:double-SIS domain
20c2xhzC_



99.8 20 PDB header:isomerase
Chain: C: PDB Molecule:arabinose 5-phosphate isomerase;
PDBTitle: probing the active site of the sugar isomerase domain from e. coli2 arabinose-5-phosphate isomerase via x-ray crystallography
21c3etnD_



not modelled 99.8 22 PDB header:isomerase
Chain: D: PDB Molecule:putative phosphosugar isomerase involved in capsule
PDBTitle: crystal structure of putative phosphosugar isomerase involved in2 capsule formation (yp_209877.1) from bacteroides fragilis nctc 93433 at 1.70 a resolution
22c1nriA_



not modelled 99.8 20 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein hi0754;
PDBTitle: crystal structure of putative phosphosugar isomerase hi0754 from2 haemophilus influenzae
23d1nria_



not modelled 99.8 20 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
24c3fxaA_



not modelled 99.8 18 PDB header:sugar binding protein
Chain: A: PDB Molecule:sis domain protein;
PDBTitle: crystal structure of a putative sugar-phosphate isomerase2 (lmof2365_0531) from listeria monocytogenes str. 4b f2365 at 1.60 a3 resolution
25d1vima_



not modelled 99.7 16 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
26c3shoA_



not modelled 99.7 17 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, rpir family;
PDBTitle: crystal structure of rpir transcription factor from sphaerobacter2 thermophilus (sugar isomerase domain)
27d1tk9a_



not modelled 99.7 17 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
28d1x94a_



not modelled 99.7 16 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
29d1m3sa_



not modelled 99.6 18 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
30c2x3yA_



not modelled 99.6 21 PDB header:isomerase
Chain: A: PDB Molecule:phosphoheptose isomerase;
PDBTitle: crystal structure of gmha from burkholderia pseudomallei
31c3cvjB_



not modelled 99.6 13 PDB header:isomerase
Chain: B: PDB Molecule:putative phosphoheptose isomerase;
PDBTitle: crystal structure of a putative phosphoheptose isomerase (bh3325) from2 bacillus halodurans c-125 at 2.00 a resolution
32d1x92a_



not modelled 99.5 15 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
33c3trjC_



not modelled 99.5 19 PDB header:isomerase
Chain: C: PDB Molecule:phosphoheptose isomerase;
PDBTitle: structure of a phosphoheptose isomerase from francisella tularensis
34d1jeoa_



not modelled 99.5 12 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
35c2yvaB_



not modelled 99.5 24 PDB header:dna binding protein
Chain: B: PDB Molecule:dnaa initiator-associating protein diaa;
PDBTitle: crystal structure of escherichia coli diaa
36c1zzgB_



not modelled 98.3 15 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: crystal structure of hypothetical protein tt0462 from thermus2 thermophilus hb8
37c2q8nB_



not modelled 98.2 15 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: crystal structure of glucose-6-phosphate isomerase (ec2 5.3.1.9) (tm1385) from thermotoga maritima at 1.82 a3 resolution
38d1c7qa_



not modelled 98.2 16 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
39c3ff1B_



not modelled 98.1 14 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: structure of glucose 6-phosphate isomerase from staphylococcus aureus
40c3hjbA_



not modelled 98.0 15 PDB header:isomerase
Chain: A: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: 1.5 angstrom crystal structure of glucose-6-phosphate isomerase from2 vibrio cholerae.
41d1gzda_



not modelled 98.0 13 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
42c3ljkA_



not modelled 98.0 15 PDB header:isomerase
Chain: A: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: glucose-6-phosphate isomerase from francisella tularensis.
43c2wu8A_



not modelled 98.0 17 PDB header:isomerase
Chain: A: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: structural studies of phosphoglucose isomerase from2 mycobacterium tuberculosis h37rv
44d1u0fa_



not modelled 98.0 15 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
45c3pr3B_



not modelled 98.0 12 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: crystal structure of plasmodium falciparum glucose-6-phosphate2 isomerase (pf14_0341) in complex with fructose-6-phosphate
46c3ujhB_



not modelled 98.0 14 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: crystal structure of substrate-bound glucose-6-phosphate isomerase2 from toxoplasma gondii
47c2o2cB_



not modelled 97.9 13 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase, glycosomal;
PDBTitle: crystal structure of phosphoglucose isomerase from t. brucei2 containing glucose-6-phosphate in the active site
48d1iata_



not modelled 97.9 13 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
49d1hm5a_



not modelled 97.9 14 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
50c1t10A_



not modelled 97.8 12 PDB header:isomerase
Chain: A: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: phosphoglucose isomerase from leishmania mexicana in complex with2 substrate d-fructose-6-phosphate
51d1q50a_



not modelled 97.8 14 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
52c3nbuC_



not modelled 97.8 16 PDB header:isomerase
Chain: C: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: crystal structure of pgi glucosephosphate isomerase
53d1wiwa_



not modelled 92.8 15 Fold:SIS domain
Superfamily:SIS domain
Family:double-SIS domain
54d1pjza_



not modelled 82.7 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Thiopurine S-methyltransferase
55c3iabB_



not modelled 76.3 13 PDB header:hydrolase/rna
Chain: B: PDB Molecule:ribonucleases p/mrp protein subunit pop7;
PDBTitle: crystal structure of rnase p /rnase mrp proteins pop6, pop72 in a complex with the p3 domain of rnase mrp rna
56d2bzga1



not modelled 75.6 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Thiopurine S-methyltransferase
57c3bgdB_



not modelled 69.8 17 PDB header:transferase
Chain: B: PDB Molecule:thiopurine s-methyltransferase;
PDBTitle: thiopurine s-methyltransferase
58d2ieaa3



not modelled 64.9 21 Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Transketolase C-terminal domain-like
59d2dw4a2



not modelled 60.4 28 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD-linked reductases, N-terminal domain
60d1w6ta1



not modelled 57.0 19 Fold:TIM beta/alpha-barrel
Superfamily:Enolase C-terminal domain-like
Family:Enolase
61d1pkla3



not modelled 54.2 27 Fold:Pyruvate kinase C-terminal domain-like
Superfamily:PK C-terminal domain-like
Family:Pyruvate kinase, C-terminal domain
62c2bi8A_



not modelled 52.8 31 PDB header:isomerase
Chain: A: PDB Molecule:udp-galactopyranose mutase;
PDBTitle: udp-galactopyranose mutase from klebsiella pneumoniae with2 reduced fad
63c3otrC_



not modelled 51.0 16 PDB header:lyase
Chain: C: PDB Molecule:enolase;
PDBTitle: 2.75 angstrom crystal structure of enolase 1 from toxoplasma gondii
64d2ptza1



not modelled 50.6 14 Fold:TIM beta/alpha-barrel
Superfamily:Enolase C-terminal domain-like
Family:Enolase
65d1a9xa4



not modelled 49.8 15 Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:BC N-terminal domain-like
66d1e0ta3



not modelled 49.7 32 Fold:Pyruvate kinase C-terminal domain-like
Superfamily:PK C-terminal domain-like
Family:Pyruvate kinase, C-terminal domain
67d2bkwa1



not modelled 49.6 13 Fold:PLP-dependent transferase-like
Superfamily:PLP-dependent transferases
Family:Cystathionine synthase-like
68d1xjca_



not modelled 49.1 13 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
69c2e1mA_



not modelled 48.4 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-glutamate oxidase;
PDBTitle: crystal structure of l-glutamate oxidase from streptomyces sp. x-119-6
70c2bpoA_



not modelled 47.8 13 PDB header:reductase
Chain: A: PDB Molecule:nadph-cytochrom p450 reductase;
PDBTitle: crystal structure of the yeast cpr triple mutant: d74g,2 y75f, k78a.
71c1kjjA_



not modelled 47.0 13 PDB header:transferase
Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase 2;
PDBTitle: crystal structure of glycniamide ribonucleotide2 transformylase in complex with mg-atp-gamma-s
72c3rhtB_



not modelled 45.9 10 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:(gatase1)-like protein;
PDBTitle: crystal structure of type 1 glutamine amidotransferase (gatase1)-like2 protein from planctomyces limnophilus
73d1iyxa1



not modelled 45.7 15 Fold:TIM beta/alpha-barrel
Superfamily:Enolase C-terminal domain-like
Family:Enolase
74c1sezA_



not modelled 43.8 27 PDB header:oxidoreductase
Chain: A: PDB Molecule:protoporphyrinogen oxidase, mitochondrial;
PDBTitle: crystal structure of protoporphyrinogen ix oxidase
75c1vkrA_



not modelled 43.6 25 PDB header:transferase
Chain: A: PDB Molecule:mannitol-specific pts system enzyme iiabc components;
PDBTitle: structure of iib domain of the mannitol-specific permease enzyme ii
76d1vkra_



not modelled 43.6 25 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:PTS system IIB component-like
Family:PTS system, Lactose/Cellobiose specific IIB subunit
77c2xagA_



not modelled 43.4 28 PDB header:transcription
Chain: A: PDB Molecule:lysine-specific histone demethylase 1;
PDBTitle: crystal structure of lsd1-corest in complex with para-bromo-2 (-)-trans-2-phenylcyclopropyl-1-amine
78c2v1dA_



not modelled 43.4 28 PDB header:oxidoreductase/repressor
Chain: A: PDB Molecule:lysine-specific histone demethylase 1;
PDBTitle: structural basis of lsd1-corest selectivity in histone h32 recognition
79c2hkoA_



not modelled 43.4 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:lysine-specific histone demethylase 1;
PDBTitle: crystal structure of lsd1
80d1a3xa3



not modelled 43.0 19 Fold:Pyruvate kinase C-terminal domain-like
Superfamily:PK C-terminal domain-like
Family:Pyruvate kinase, C-terminal domain
81d1a7ja_



not modelled 40.8 13 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Phosphoribulokinase/pantothenate kinase
82c3fpjA_



not modelled 40.8 10 PDB header:biosynthetic protein, transferase
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of e81q mutant of mtnas in complex with s-2 adenosylmethionine
83d1reoa1



not modelled 39.4 23 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD-linked reductases, N-terminal domain
84d2g50a3



not modelled 39.3 17 Fold:Pyruvate kinase C-terminal domain-like
Superfamily:PK C-terminal domain-like
Family:Pyruvate kinase, C-terminal domain
85d1pdza1



not modelled 38.3 16 Fold:TIM beta/alpha-barrel
Superfamily:Enolase C-terminal domain-like
Family:Enolase
86c2yxbA_



not modelled 36.5 5 PDB header:isomerase
Chain: A: PDB Molecule:coenzyme b12-dependent mutase;
PDBTitle: crystal structure of the methylmalonyl-coa mutase alpha-subunit from2 aeropyrum pernix
87c1xx6B_



not modelled 35.6 16 PDB header:transferase
Chain: B: PDB Molecule:thymidine kinase;
PDBTitle: x-ray structure of clostridium acetobutylicum thymidine kinase with2 adp. northeast structural genomics target car26.
88c3khdC_



not modelled 35.5 22 PDB header:transferase
Chain: C: PDB Molecule:pyruvate kinase;
PDBTitle: crystal structure of pff1300w.
89c2jb1B_



not modelled 35.5 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:l-amino acid oxidase;
PDBTitle: the l-amino acid oxidase from rhodococcus opacus in complex2 with l-alanine
90c1f8sA_



not modelled 35.4 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-amino acid oxidase;
PDBTitle: crystal structure of l-amino acid oxidase from calloselasma2 rhodostoma, complexed with three molecules of o-aminobenzoate.
91c3q2oB_



not modelled 35.4 14 PDB header:lyase
Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase, atpase subunit;
PDBTitle: crystal structure of purk: n5-carboxyaminoimidazole ribonucleotide2 synthetase
92c1a3wB_



not modelled 34.9 25 PDB header:transferase
Chain: B: PDB Molecule:pyruvate kinase;
PDBTitle: pyruvate kinase from saccharomyces cerevisiae complexed with fbp, pg,2 mn2+ and k+
93c2hcuA_



not modelled 34.5 23 PDB header:lyase
Chain: A: PDB Molecule:3-isopropylmalate dehydratase small subunit;
PDBTitle: crystal structure of smu.1381 (or leud) from streptococcus2 mutans
94c2vgbB_



not modelled 33.9 17 PDB header:transferase
Chain: B: PDB Molecule:pyruvate kinase isozymes r/l;
PDBTitle: human erythrocyte pyruvate kinase
95c3allA_



not modelled 33.8 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase;
PDBTitle: crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid2 oxygenase, mutant y270a
96c2z2uA_



not modelled 32.8 10 PDB header:metal binding protein
Chain: A: PDB Molecule:upf0026 protein mj0257;
PDBTitle: crystal structure of archaeal tyw1
97c2z9wA_



not modelled 32.7 13 PDB header:transferase
Chain: A: PDB Molecule:aspartate aminotransferase;
PDBTitle: crystal structure of pyridoxamine-pyruvate aminotransferase complexed2 with pyridoxal
98c3eoeC_



not modelled 32.2 13 PDB header:transferase
Chain: C: PDB Molecule:pyruvate kinase;
PDBTitle: crystal structure of pyruvate kinase from toxoplasma gondii, 55.m00007
99c1e0tD_



not modelled 32.1 32 PDB header:phosphotransferase
Chain: D: PDB Molecule:pyruvate kinase;
PDBTitle: r292d mutant of e. coli pyruvate kinase
100c3kpgA_



not modelled 31.6 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:sulfide-quinone reductase, putative;
PDBTitle: crystal structure of sulfide:quinone oxidoreductase from2 acidithiobacillus ferrooxidans in complex with decylubiquinone
101d1v8ba2



not modelled 31.5 12 Fold:Flavodoxin-like
Superfamily:Formate/glycerate dehydrogenase catalytic domain-like
Family:S-adenosylhomocystein hydrolase
102c3h5jA_



not modelled 31.4 20 PDB header:lyase
Chain: A: PDB Molecule:3-isopropylmalate dehydratase small subunit;
PDBTitle: leud_1-168 small subunit of isopropylmalate isomerase (rv2987c) from2 mycobacterium tuberculosis
103c3lovA_



not modelled 31.3 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:protoporphyrinogen oxidase;
PDBTitle: crystal structure of putative protoporphyrinogen oxidase2 (yp_001813199.1) from exiguobacterium sp. 255-15 at 2.06 a resolution
104d1ycga1



not modelled 31.1 4 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
105c3edoA_



not modelled 30.1 17 PDB header:flavoprotein
Chain: A: PDB Molecule:putative trp repressor binding protein;
PDBTitle: crystal structure of flavoprotein in complex with fmn2 (yp_193882.1) from lactobacillus acidophilus ncfm at 1.203 a resolution
106c1dl5A_



not modelled 30.1 17 PDB header:transferase
Chain: A: PDB Molecule:protein-l-isoaspartate o-methyltransferase;
PDBTitle: protein-l-isoaspartate o-methyltransferase
107d2bfdb2



not modelled 29.7 16 Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain
108d1v8da_



not modelled 29.4 24 Fold:TTHA0583/YokD-like
Superfamily:TTHA0583/YokD-like
Family:Hypothetical protein TT1679
109c3b2nA_



not modelled 29.1 9 PDB header:transcription
Chain: A: PDB Molecule:uncharacterized protein q99uf4;
PDBTitle: crystal structure of dna-binding response regulator, luxr family, from2 staphylococcus aureus
110d7reqa2



not modelled 28.9 15 Fold:Flavodoxin-like
Superfamily:Cobalamin (vitamin B12)-binding domain
Family:Cobalamin (vitamin B12)-binding domain
111d2b3ya1



not modelled 28.8 18 Fold:The "swivelling" beta/beta/alpha domain
Superfamily:LeuD/IlvD-like
Family:LeuD-like
112c2pxxA_



not modelled 28.4 28 PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein mgc2408;
PDBTitle: human putative methyltransferase mgc2408
113d2bi7a1



not modelled 28.3 32 Fold:Nucleotide-binding domain
Superfamily:Nucleotide-binding domain
Family:UDP-galactopyranose mutase, N-terminal domain
114c3uvzB_



not modelled 28.2 16 PDB header:lyase
Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase, atpase subunit;
PDBTitle: crystal structure of phosphoribosylaminoimidazole carboxylase, atpase2 subunit from burkholderia ambifaria
115d1ka9h_



not modelled 28.0 19 Fold:Flavodoxin-like
Superfamily:Class I glutamine amidotransferase-like
Family:Class I glutamine amidotransferases (GAT)
116d2al1a1



not modelled 28.0 13 Fold:TIM beta/alpha-barrel
Superfamily:Enolase C-terminal domain-like
Family:Enolase
117c3q3wB_



not modelled 28.0 23 PDB header:transferase
Chain: B: PDB Molecule:3-isopropylmalate dehydratase small subunit;
PDBTitle: isopropylmalate isomerase small subunit from campylobacter jejuni.
118c3i9fB_



not modelled 27.0 13 PDB header:transferase
Chain: B: PDB Molecule:putative type 11 methyltransferase;
PDBTitle: crystal structure of a putative type 11 methyltransferase2 from sulfolobus solfataricus
119c1l8pC_



not modelled 26.5 13 PDB header:lyase
Chain: C: PDB Molecule:enolase 1;
PDBTitle: mg-phosphonoacetohydroxamate complex of s39a yeast enolase 1
120c1v0jB_



not modelled 26.5 22 PDB header:isomerase
Chain: B: PDB Molecule:udp-galactopyranose mutase;
PDBTitle: udp-galactopyranose mutase from mycobacterium tuberculosis

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0