Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	M	K	T	M	R	I	A	A	I	P	G	D	G	I	G	K	E	V	L	P	E	G	I	R	V	L	Q	A	A	A	E	R	W	G	F	A	L	S	F	E	Q	M	E	W	A	S	C	E	Y	Y	S	H	H	G	K	M	M	P	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	W	H	E	Q	L	S	R	F	D	A	I	Y	F	G	A	V	G	W	P	D	T	V	P	D	H	I	S	L	W	G	S	L	L	K	F	R	R	E	F	D	Q	Y	V	N	L	R	P	V	R	L	F	P	G	V	P	C	P	L	A
Secondary structure
SS confidence
Disorder																					?	?		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	K	Q	P	G	D	I	D	F	Y	V	V	R	E	N	T	E	G	E	Y	S	S	L	G	G	R	V	N	E	G	T	E	H	E	V	V	I	Q	E	S	V	F	T	R	R	G	V	D	R	I	L	R	Y	A	F	E	L	A	Q	S
Secondary structure
SS confidence
Disorder																											?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		R	P	R	K	T	L	T	S	A	T	K	S	N	G	L	A	I	S	M	P	Y	W	D	E	R	V	E	A	M	A	E	N	Y	P	E	I	R	W	D	K	Q	H	I	D	I	L	C	A	R	F	V	M	Q	P	E	R	F	D	V	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		V	A	S	N	L	F	G	D	I	L	S	D	L	G	P	A	C	T	G	T	I	G	I	A	P	S	A	N	L	N	P	E	R	T	F	P	S	L	F	E	P	V	H	G	S	A	P	D	I	Y	G	K	N	I	A	N	P	I	A	T
Secondary structure
SS confidence
Disorder																		?																																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		I	W	A	G	A	M	M	L	D	F	L	G	N	G	D	E	R	F	Q	Q	A	H	N	G	I	L	A	A	I	E	E	V	I	A	H	G	P	K	T	P	D	M	K	G	N	A	T	T	P	Q	V	A	D	A	I	C	K	I	I	L
Secondary structure
SS confidence
Disorder																																																												?	?
Disorder confidence
		.
Sequence		R
Secondary structure
SS confidence
Disorder		?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3fmx chain X Region: 4 - 361 Aligned: 358 Modelled: 358 Confidence: 100.0% Identity: 78% PDB header:oxidoreductase Chain: X: PDB Molecule:tartrate dehydrogenase/decarboxylase; PDBTitle: crystal structure of tartrate dehydrogenase from pseudomonas2 putida complexed with nadh Phyre2 PDB 2d1c chain B Region: 4 - 361 Aligned: 334 Modelled: 354 Confidence: 100.0% Identity: 35% PDB header:oxidoreductase Chain: B: PDB Molecule:isocitrate dehydrogenase; PDBTitle: crystal structure of tt0538 protein from thermus thermophilus hb8 Phyre2 PDB 1cm7 chain A Region: 1 - 361 Aligned: 350 Modelled: 360 Confidence: 100.0% Identity: 38% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1pb1 chain A Region: 2 - 359 Aligned: 343 Modelled: 358 Confidence: 100.0% Identity: 29% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1v53 chain A domain 1 Region: 2 - 359 Aligned: 345 Modelled: 356 Confidence: 100.0% Identity: 36% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1cnz chain A Region: 1 - 361 Aligned: 350 Modelled: 361 Confidence: 100.0% Identity: 37% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1a05 chain A Region: 2 - 361 Aligned: 347 Modelled: 357 Confidence: 100.0% Identity: 34% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 3r8w chain C Region: 3 - 360 Aligned: 348 Modelled: 355 Confidence: 100.0% Identity: 36% PDB header:oxidoreductase Chain: C: PDB Molecule:3-isopropylmalate dehydrogenase 2, chloroplastic; PDBTitle: structure of 3-isopropylmalate dehydrogenase isoform 2 from2 arabidopsis thaliana at 2.2 angstrom resolution Phyre2 PDB 2d4v chain D Region: 2 - 359 Aligned: 343 Modelled: 358 Confidence: 100.0% Identity: 29% PDB header:oxidoreductase Chain: D: PDB Molecule:isocitrate dehydrogenase; PDBTitle: crystal structure of nad dependent isocitrate dehydrogenase2 from acidithiobacillus thiooxidans Phyre2 PDB 1g2u chain A Region: 5 - 360 Aligned: 340 Modelled: 356 Confidence: 100.0% Identity: 36% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1xac chain A Region: 5 - 360 Aligned: 340 Modelled: 356 Confidence: 100.0% Identity: 36% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1hqs chain A Region: 2 - 360 Aligned: 345 Modelled: 358 Confidence: 100.0% Identity: 31% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1vlc chain A Region: 2 - 361 Aligned: 344 Modelled: 360 Confidence: 100.0% Identity: 36% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 2e0c chain A Region: 2 - 361 Aligned: 337 Modelled: 358 Confidence: 100.0% Identity: 30% PDB header:oxidoreductase Chain: A: PDB Molecule:409aa long hypothetical nadp-dependent isocitrate PDBTitle: crystal structure of isocitrate dehydrogenase from sulfolobus tokodaii2 strain7 at 2.0 a resolution Phyre2 PDB 3u1h chain A Region: 6 - 361 Aligned: 338 Modelled: 355 Confidence: 100.0% Identity: 40% PDB header:oxidoreductase Chain: A: PDB Molecule:3-isopropylmalate dehydrogenase; PDBTitle: crystal structure of ipmdh from the last common ancestor of bacillus Phyre2 PDB 1wpw chain A Region: 5 - 359 Aligned: 331 Modelled: 355 Confidence: 100.0% Identity: 34% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1x0l chain B Region: 4 - 361 Aligned: 325 Modelled: 352 Confidence: 100.0% Identity: 42% PDB header:oxidoreductase Chain: B: PDB Molecule:homoisocitrate dehydrogenase; PDBTitle: crystal structure of tetrameric homoisocitrate dehydrogenase from an2 extreme thermophile, thermus thermophilus Phyre2 PDB 1w0d chain A Region: 5 - 359 Aligned: 336 Modelled: 355 Confidence: 100.0% Identity: 41% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 3blx chain L Region: 2 - 359 Aligned: 327 Modelled: 358 Confidence: 100.0% Identity: 33% PDB header:oxidoreductase Chain: L: PDB Molecule:isocitrate dehydrogenase [nad] subunit 2; PDBTitle: yeast isocitrate dehydrogenase (apo form) Phyre2 PDB 1tyo chain A Region: 2 - 361 Aligned: 344 Modelled: 355 Confidence: 100.0% Identity: 26% PDB header:oxidoreductase Chain: A: PDB Molecule:isocitrate dehydrogenase; PDBTitle: isocitrate dehydrogenase from the hyperthermophile aeropyrum pernix in2 complex with etheno-nadp Phyre2 1 c3fmxX_ 2 c2d1cB_ 3 d1cm7a_ 4 d1pb1a_ 5 d1v53a1 6 d1cnza_ 7 d1a05a_ 8 c3r8wC_ 9 c2d4vD_ 10 d1g2ua_ 11 d1xaca_ 12 d1hqsa_ 13 d1vlca_ 14 c2e0cA_ 15 c3u1hA_ 16 d1wpwa_ 17 c1x0lB_ 18 d1w0da_ 19 c3blxL_ 20 c1tyoA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3fmxX_ 100.0 78 PDB header:oxidoreductase Chain: X: PDB Molecule:tartrate dehydrogenase/decarboxylase; PDBTitle: crystal structure of tartrate dehydrogenase from pseudomonas2 putida complexed with nadh 2 c2d1cB_ 100.0 35 PDB header:oxidoreductase Chain: B: PDB Molecule:isocitrate dehydrogenase; PDBTitle: crystal structure of tt0538 protein from thermus thermophilus hb8 3 d1cm7a_ 100.0 38 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 4 d1pb1a_ 100.0 29 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 5 d1v53a1 100.0 36 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 6 d1cnza_ 100.0 37 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 7 d1a05a_ 100.0 34 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 8 c3r8wC_ 100.0 36 PDB header:oxidoreductase Chain: C: PDB Molecule:3-isopropylmalate dehydrogenase 2, chloroplastic; PDBTitle: structure of 3-isopropylmalate dehydrogenase isoform 2 from2 arabidopsis thaliana at 2.2 angstrom resolution 9 c2d4vD_ 100.0 29 PDB header:oxidoreductase Chain: D: PDB Molecule:isocitrate dehydrogenase; PDBTitle: crystal structure of nad dependent isocitrate dehydrogenase2 from acidithiobacillus thiooxidans 10 d1g2ua_ 100.0 36 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 11 d1xaca_ 100.0 36 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 12 d1hqsa_ 100.0 31 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 13 d1vlca_ 100.0 36 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 14 c2e0cA_ 100.0 30 PDB header:oxidoreductase Chain: A: PDB Molecule:409aa long hypothetical nadp-dependent isocitrate PDBTitle: crystal structure of isocitrate dehydrogenase from sulfolobus tokodaii2 strain7 at 2.0 a resolution 15 c3u1hA_ 100.0 40 PDB header:oxidoreductase Chain: A: PDB Molecule:3-isopropylmalate dehydrogenase; PDBTitle: crystal structure of ipmdh from the last common ancestor of bacillus 16 d1wpwa_ 100.0 34 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 17 c1x0lB_ 100.0 42 PDB header:oxidoreductase Chain: B: PDB Molecule:homoisocitrate dehydrogenase; PDBTitle: crystal structure of tetrameric homoisocitrate dehydrogenase from an2 extreme thermophile, thermus thermophilus 18 d1w0da_ 100.0 41 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 19 c3blxL_ 100.0 33 PDB header:oxidoreductase Chain: L: PDB Molecule:isocitrate dehydrogenase [nad] subunit 2; PDBTitle: yeast isocitrate dehydrogenase (apo form) 20 c1tyoA_ 100.0 26 PDB header:oxidoreductase Chain: A: PDB Molecule:isocitrate dehydrogenase; PDBTitle: isocitrate dehydrogenase from the hyperthermophile aeropyrum pernix in2 complex with etheno-nadp 21 c3blxM_ not modelled 100.0 31 PDB header:oxidoreductase Chain: M: PDB Molecule:isocitrate dehydrogenase [nad] subunit 1; PDBTitle: yeast isocitrate dehydrogenase (apo form) 22 c1zorB_ not modelled 100.0 18 PDB header:oxidoreductase Chain: B: PDB Molecule:isocitrate dehydrogenase; PDBTitle: isocitrate dehydrogenase from the hyperthermophile thermotoga maritima 23 c2uxqB_ not modelled 100.0 20 PDB header:oxidoreductase Chain: B: PDB Molecule:isocitrate dehydrogenase native; PDBTitle: isocitrate dehydrogenase from the psychrophilic bacterium2 desulfotalea psychrophila: biochemical properties and3 crystal structure analysis 24 d1lwda_ not modelled 100.0 18 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 25 c3us8A_ not modelled 100.0 16 PDB header:oxidoreductase Chain: A: PDB Molecule:isocitrate dehydrogenase [nadp]; PDBTitle: crystal structure of an isocitrate dehydrogenase from sinorhizobium2 meliloti 1021 26 d1t0la_ not modelled 100.0 17 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 27 c2qfyE_ not modelled 100.0 19 PDB header:oxidoreductase Chain: E: PDB Molecule:isocitrate dehydrogenase [nadp]; PDBTitle: crystal structure of saccharomyces cerevesiae mitochondrial nadp(+)-2 dependent isocitrate dehydrogenase in complex with a-ketoglutarate 28 c2iv0A_ not modelled 100.0 32 PDB header:oxidoreductase Chain: A: PDB Molecule:isocitrate dehydrogenase; PDBTitle: thermal stability of isocitrate dehydrogenase from2 archaeoglobus fulgidus studied by crystal structure3 analysis and engineering of chimers 29 c2hi1A_ not modelled 99.0 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:4-hydroxythreonine-4-phosphate dehydrogenase 2; PDBTitle: the structure of a putative 4-hydroxythreonine-4-phosphate2 dehydrogenase from salmonella typhimurium. 30 d1ptma_ not modelled 99.0 16 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:PdxA-like 31 d1r8ka_ not modelled 98.8 17 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:PdxA-like 32 c1yxoB_ not modelled 98.5 16 PDB header:oxidoreductase Chain: B: PDB Molecule:4-hydroxythreonine-4-phosphate dehydrogenase 1; PDBTitle: crystal structure of pyridoxal phosphate biosynthetic protein pdxa2 pa0593 33 d1itwa_ not modelled 98.1 18 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Monomeric isocitrate dehydrogenase 34 c2b0tA_ not modelled 98.0 14 PDB header:oxidoreductase Chain: A: PDB Molecule:nadp isocitrate dehydrogenase; PDBTitle: structure of monomeric nadp isocitrate dehydrogenase 35 c2q62A_ not modelled 77.0 10 PDB header:flavoprotein Chain: A: PDB Molecule:arsh; PDBTitle: crystal structure of arsh from sinorhizobium meliloti 36 d2fpoa1 not modelled 66.7 10 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 37 c1p84E_ not modelled 57.1 32 PDB header:oxidoreductase Chain: E: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur PDBTitle: hdbt inhibited yeast cytochrome bc1 complex 38 d2onsa1 not modelled 53.1 13 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 39 c3cfxA_ not modelled 53.0 12 PDB header:transport protein Chain: A: PDB Molecule:upf0100 protein ma_0280; PDBTitle: crystal structure of m. acetivorans periplasmic binding protein2 moda/wtpa with bound tungstate 40 c2fyuE_ not modelled 51.8 32 PDB header:oxidoreductase Chain: E: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur subunit, PDBTitle: crystal structure of bovine heart mitochondrial bc1 with jg1442 inhibitor 41 c3s40C_ not modelled 49.1 11 PDB header:transferase Chain: C: PDB Molecule:diacylglycerol kinase; PDBTitle: the crystal structure of a diacylglycerol kinases from bacillus2 anthracis str. sterne 42 c3cfzA_ not modelled 48.2 9 PDB header:transport protein Chain: A: PDB Molecule:upf0100 protein mj1186; PDBTitle: crystal structure of m. jannaschii periplasmic binding2 protein moda/wtpa with bound tungstate 43 d3thia_ not modelled 44.0 18 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 44 d1riea_ not modelled 41.0 32 Fold:ISP domain Superfamily:ISP domain Family:Rieske iron-sulfur protein (ISP) 45 c3k6wA_ not modelled 40.4 12 PDB header:transport protein Chain: A: PDB Molecule:solute-binding protein ma_0280; PDBTitle: apo and ligand bound structures of moda from the archaeon2 methanosarcina acetivorans 46 c2fynO_ not modelled 39.6 29 PDB header:oxidoreductase Chain: O: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur PDBTitle: crystal structure analysis of the double mutant rhodobacter2 sphaeroides bc1 complex 47 c1orhA_ not modelled 37.3 10 PDB header:transferase Chain: A: PDB Molecule:protein arginine n-methyltransferase 1; PDBTitle: structure of the predominant protein arginine methyltransferase prmt1 48 d1oria_ not modelled 36.4 10 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Arginine methyltransferase 49 d3cx5e1 not modelled 32.1 32 Fold:ISP domain Superfamily:ISP domain Family:Rieske iron-sulfur protein (ISP) 50 c2e76D_ not modelled 28.5 38 PDB header:photosynthesis Chain: D: PDB Molecule:cytochrome b6-f complex iron-sulfur subunit; PDBTitle: crystal structure of the cytochrome b6f complex with tridecyl-2 stigmatellin (tds) from m.laminosus 51 c1twyG_ not modelled 26.8 16 PDB header:structural genomics, unknown function Chain: G: PDB Molecule:abc transporter, periplasmic substrate-binding protein; PDBTitle: crystal structure of an abc-type phosphate transport receptor from2 vibrio cholerae 52 d1twya_ not modelled 26.8 16 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 53 c3fzgA_ not modelled 25.7 6 PDB header:transferase Chain: A: PDB Molecule:16s rrna methylase; PDBTitle: structure of the 16s rrna methylase arma 54 c3grzA_ not modelled 24.6 23 PDB header:transferase Chain: A: PDB Molecule:ribosomal protein l11 methyltransferase; PDBTitle: crystal structure of ribosomal protein l11 methylase from2 lactobacillus delbrueckii subsp. bulgaricus 55 c2nvgA_ not modelled 24.1 26 PDB header:oxidoreductase Chain: A: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur subunit; PDBTitle: soluble domain of rieske iron sulfur protein. 56 c3qd7X_ not modelled 23.5 5 PDB header:hydrolase Chain: X: PDB Molecule:uncharacterized protein ydal; PDBTitle: crystal structure of ydal, a stand-alone small muts-related protein2 from escherichia coli 57 d1ydga_ not modelled 23.1 15 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:WrbA-like 58 d2fyta1 not modelled 22.9 12 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Arginine methyltransferase 59 c2huzB_ not modelled 17.2 13 PDB header:structural genomics, transferase Chain: B: PDB Molecule:glucosamine 6-phosphate n-acetyltransferase; PDBTitle: crystal structure of gnpnat1 60 d2fcaa1 not modelled 16.2 10 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:TrmB-like 61 c3lwzC_ not modelled 16.1 24 PDB header:lyase Chain: C: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: 1.65 angstrom resolution crystal structure of type ii 3-2 dehydroquinate dehydratase (aroq) from yersinia pestis 62 d2z3va1 not modelled 16.0 12 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 63 d1t0ia_ not modelled 15.8 19 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:NADPH-dependent FMN reductase 64 d1yzha1 not modelled 15.5 6 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:TrmB-like 65 d1g6q1_ not modelled 15.3 10 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Arginine methyltransferase 66 c3ksmA_ not modelled 15.2 13 PDB header:transport protein Chain: A: PDB Molecule:abc-type sugar transport system, periplasmic component; PDBTitle: crystal structure of abc-type sugar transport system, periplasmic2 component from hahella chejuensis 67 c2pebB_ not modelled 15.1 22 PDB header:oxidoreductase Chain: B: PDB Molecule:putative dioxygenase; PDBTitle: crystal structure of a putative dioxygenase (npun_f1925) from nostoc2 punctiforme pcc 73102 at 1.46 a resolution 68 c2qhxB_ not modelled 15.0 18 PDB header:oxidoreductase Chain: B: PDB Molecule:pteridine reductase 1; PDBTitle: structure of pteridine reductase from leishmania major2 complexed with a ligand 69 d1n1jb_ not modelled 14.9 11 Fold:Histone-fold Superfamily:Histone-fold Family:TBP-associated factors, TAFs 70 d1tzyb_ not modelled 14.8 38 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 71 c3fg9B_ not modelled 14.6 18 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:protein of universal stress protein uspa family; PDBTitle: the crystal structure of an universal stress protein uspa2 family protein from lactobacillus plantarum wcfs1 72 d1ofda1 not modelled 14.6 19 Fold:Single-stranded right-handed beta-helix Superfamily:Alpha subunit of glutamate synthase, C-terminal domain Family:Alpha subunit of glutamate synthase, C-terminal domain 73 d1hioa_ not modelled 13.4 11 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 74 d1cyxa_ not modelled 13.3 21 Fold:Cupredoxin-like Superfamily:Cupredoxins Family:Periplasmic domain of cytochrome c oxidase subunit II 75 c1cyxA_ not modelled 13.3 21 PDB header:electron transport Chain: A: PDB Molecule:cyoa; PDBTitle: quinol oxidase (periplasmic fragment of subunit ii with2 engineered cu-a binding site)(cyoa) 76 d1r5ja_ not modelled 13.2 17 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Phosphotransacetylase 77 c2uvgA_ not modelled 13.2 14 PDB header:sugar-binding protein Chain: A: PDB Molecule:abc type periplasmic sugar-binding protein; PDBTitle: structure of a periplasmic oligogalacturonide binding2 protein from yersinia enterocolitica 78 c1f66C_ not modelled 12.6 11 PDB header:structural protein/dna Chain: C: PDB Molecule:histone h2a.z; PDBTitle: 2.6 a crystal structure of a nucleosome core particle2 containing the variant histone h2a.z 79 d1f66c_ not modelled 12.6 11 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 80 c2hxrA_ not modelled 11.9 15 PDB header:transcription Chain: A: PDB Molecule:hth-type transcriptional regulator cynr; PDBTitle: structure of the ligand binding domain of e. coli cynr, a2 transcriptional regulator controlling cyanate metabolism 81 c3er6D_ not modelled 11.8 17 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:putative transcriptional regulator protein; PDBTitle: crystal structure of a putative transcriptional regulator2 protein from vibrio parahaemolyticus 82 d1id3d_ not modelled 11.8 29 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 83 d1n1ja_ not modelled 11.6 16 Fold:Histone-fold Superfamily:Histone-fold Family:TBP-associated factors, TAFs 84 c3b3jA_ not modelled 11.6 14 PDB header:transferase Chain: A: PDB Molecule:histone-arginine methyltransferase carm1; PDBTitle: the 2.55 a crystal structure of the apo catalytic domain of2 coactivator-associated arginine methyl transferase i(carm1:28-507,3 residues 28-146 and 479-507 not ordered) 85 d1i27a_ not modelled 11.5 22 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:C-terminal domain of the rap74 subunit of TFIIF 86 d2jssa1 not modelled 11.5 14 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 87 c2f8nK_ not modelled 11.4 11 PDB header:structural protein/dna Chain: K: PDB Molecule:histone h2a type 1; PDBTitle: 2.9 angstrom x-ray structure of hybrid macroh2a nucleosomes 88 c3c6kC_ not modelled 11.2 10 PDB header:transferase Chain: C: PDB Molecule:spermine synthase; PDBTitle: crystal structure of human spermine synthase in complex2 with spermidine and 5-methylthioadenosine 89 c2qv7A_ not modelled 11.0 13 PDB header:transferase Chain: A: PDB Molecule:diacylglycerol kinase dgkb; PDBTitle: crystal structure of diacylglycerol kinase dgkb in complex with adp2 and mg 90 d1fftb1 not modelled 10.8 21 Fold:Cupredoxin-like Superfamily:Cupredoxins Family:Periplasmic domain of cytochrome c oxidase subunit II 91 d1e7wa_ not modelled 10.7 18 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 92 d1i7na1 not modelled 10.6 25 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:Synapsin domain 93 d1jq4a_ not modelled 10.4 23 Fold:beta-Grasp (ubiquitin-like) Superfamily:2Fe-2S ferredoxin-like Family:2Fe-2S ferredoxin domains from multidomain proteins 94 d1p3mh_ not modelled 10.4 38 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 95 c2zqeA_ not modelled 10.3 11 PDB header:dna binding protein Chain: A: PDB Molecule:muts2 protein; PDBTitle: crystal structure of the smr domain of thermus thermophilus muts2 96 d1q77a_ not modelled 10.3 13 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 97 d1ku5a_ not modelled 10.1 33 Fold:Histone-fold Superfamily:Histone-fold Family:Archaeal histone 98 d1hiob_ not modelled 10.0 38 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 99 d1tzya_ not modelled 10.0 11 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0