Emaill.a.kelley@imperial.ac.uk
DescriptionP0AFT5
DateThu Jan 5 11:27:13 GMT 2012
Unique Job ID4b6512e77f1b71b8

Detailed template information 

#Template Alignment Coverage3D Model Confidence% i.d. Template Information
1c2qv0A_



99.9 36 PDB header:transcription
Chain: A: PDB Molecule:protein mrke;
PDBTitle: crystal structure of the response regulatory domain of2 protein mrke from klebsiella pneumoniae
2c3breA_



99.9 25 PDB header:signaling protein
Chain: A: PDB Molecule:probable two-component response regulator;
PDBTitle: crystal structure of p.aeruginosa pa3702
3c3eq2A_



99.9 27 PDB header:signaling protein
Chain: A: PDB Molecule:probable two-component response regulator;
PDBTitle: structure of hexagonal crystal form of pseudomonas2 aeruginosa rssb
4c3b2nA_



99.9 24 PDB header:transcription
Chain: A: PDB Molecule:uncharacterized protein q99uf4;
PDBTitle: crystal structure of dna-binding response regulator, luxr family, from2 staphylococcus aureus
5c2ayxA_



99.9 21 PDB header:transferase
Chain: A: PDB Molecule:sensor kinase protein rcsc;
PDBTitle: solution structure of the e.coli rcsc c-terminus (residues2 700-949) containing linker region and phosphoreceiver3 domain
6c1a2oB_



99.9 28 PDB header:bacterial chemotaxis
Chain: B: PDB Molecule:cheb methylesterase;
PDBTitle: structural basis for methylesterase cheb regulation by a2 phosphorylation-activated domain
7c3t8yA_



99.9 27 PDB header:hydrolase
Chain: A: PDB Molecule:chemotaxis response regulator protein-glutamate
PDBTitle: crystal structure of the response regulator domain of thermotoga2 maritima cheb
8c3i5aA_



99.9 25 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator/ggdef domain protein;
PDBTitle: crystal structure of full-length wpsr from pseudomonas syringae
9c1w25B_



99.9 23 PDB header:signaling protein
Chain: B: PDB Molecule:stalked-cell differentiation controlling protein;
PDBTitle: response regulator pled in complex with c-digmp
10d1s8na_



99.9 30 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
11d1dz3a_



99.9 32 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
12d1ny5a1



99.9 22 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
13c1ny5A_



99.9 21 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulator (ntrc family);
PDBTitle: crystal structure of sigm54 activator (aaa+ atpase) in the inactive2 state
14c3cu5B_



99.9 27 PDB header:transcription regulator
Chain: B: PDB Molecule:two component transcriptional regulator, arac family;
PDBTitle: crystal structure of a two component transcriptional regulator arac2 from clostridium phytofermentans isdg
15d2a9pa1



99.9 26 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
16d1jbea_



99.9 27 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
17c3r0jA_



99.9 25 PDB header:dna binding protein
Chain: A: PDB Molecule:possible two component system response transcriptional
PDBTitle: structure of phop from mycobacterium tuberculosis
18d2ayxa1



99.9 21 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
19d1kgsa2



99.9 29 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
20d1a04a2



99.9 32 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
21c3eulB_



not modelled 99.9 23 PDB header:transcription
Chain: B: PDB Molecule:possible nitrate/nitrite response transcriptional
PDBTitle: structure of the signal receiver domain of the putative2 response regulator narl from mycobacterium tuberculosis
22c2zwmA_



not modelled 99.9 27 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulatory protein yycf;
PDBTitle: crystal structure of yycf receiver domain from bacillus2 subtilis
23c3cnbC_



not modelled 99.9 21 PDB header:dna binding protein
Chain: C: PDB Molecule:dna-binding response regulator, merr family;
PDBTitle: crystal structure of signal receiver domain of dna binding response2 regulator protein (merr) from colwellia psychrerythraea 34h
24d1a2oa1



not modelled 99.9 25 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
25d1u0sy_



not modelled 99.9 28 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
26c3cg0A_



not modelled 99.9 27 PDB header:lyase
Chain: A: PDB Molecule:response regulator receiver modulated diguanylate cyclase
PDBTitle: crystal structure of signal receiver domain of modulated diguanylate2 cyclase from desulfovibrio desulfuricans g20, an example of alternate3 folding
27c3cz5B_



not modelled 99.9 26 PDB header:transcription regulator
Chain: B: PDB Molecule:two-component response regulator, luxr family;
PDBTitle: crystal structure of two-component response regulator, luxr family,2 from aurantimonas sp. si85-9a1
28d1w25a1



not modelled 99.9 25 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
29d1ys7a2



not modelled 99.9 29 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
30c3dzdA_



not modelled 99.9 22 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator (ntrc family);
PDBTitle: crystal structure of sigma54 activator ntrc4 in the inactive2 state
31c2qr3A_



not modelled 99.9 24 PDB header:transcription
Chain: A: PDB Molecule:two-component system response regulator;
PDBTitle: crystal structure of the n-terminal signal receiver domain of two-2 component system response regulator from bacteroides fragilis
32c2rjnA_



not modelled 99.9 17 PDB header:hydrolase
Chain: A: PDB Molecule:response regulator receiver:metal-dependent
PDBTitle: crystal structure of an uncharacterized protein q2bku2 from2 neptuniibacter caesariensis
33c2jrlA_



not modelled 99.9 25 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulator (ntrc family);
PDBTitle: solution structure of the beryllofluoride-activated ntrc4 receiver2 domain dimer
34d1k66a_



not modelled 99.9 18 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
35c3jteA_



not modelled 99.9 26 PDB header:protein binding
Chain: A: PDB Molecule:response regulator receiver protein;
PDBTitle: crystal structure of response regulator receiver domain2 protein from clostridium thermocellum
36d1qkka_



not modelled 99.9 20 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
37c3cfyA_



not modelled 99.9 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative luxo repressor protein;
PDBTitle: crystal structure of signal receiver domain of putative luxo2 repressor protein from vibrio parahaemolyticus
38c3nhzA_



not modelled 99.9 27 PDB header:dna binding protein
Chain: A: PDB Molecule:two component system transcriptional regulator mtra;
PDBTitle: structure of n-terminal domain of mtra
39d1mvoa_



not modelled 99.9 25 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
40d1dbwa_



not modelled 99.9 25 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
41d1zh2a1



not modelled 99.9 29 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
42d1heya_



not modelled 99.9 24 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
43c3khtA_



not modelled 99.9 19 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator;
PDBTitle: crystal structure of response regulator from hahella chejuensis
44c3gt7A_



not modelled 99.9 24 PDB header:hydrolase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of signal receiver domain of signal2 transduction histidine kinase from syntrophus3 aciditrophicus
45c3hdgE_



not modelled 99.9 32 PDB header:structural genomics, unknown function
Chain: E: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of the n-terminal domain of an2 uncharacterized protein (ws1339) from wolinella3 succinogenes
46c3hebB_



not modelled 99.9 15 PDB header:transcription regulator
Chain: B: PDB Molecule:response regulator receiver domain protein (chey);
PDBTitle: crystal structure of response regulator receiver domain from2 rhodospirillum rubrum
47c2qzjC_



not modelled 99.9 25 PDB header:transcription
Chain: C: PDB Molecule:two-component response regulator;
PDBTitle: crystal structure of a two-component response regulator from2 clostridium difficile
48d2pl1a1



not modelled 99.9 25 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
49d1zgza1



not modelled 99.9 22 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
50d1peya_



not modelled 99.9 23 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
51c3crnA_



not modelled 99.9 20 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator receiver domain protein, chey-like;
PDBTitle: crystal structure of response regulator receiver domain protein (chey-2 like) from methanospirillum hungatei jf-1
52d1p6qa_



not modelled 99.9 23 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
53c3h1gA_



not modelled 99.9 27 PDB header:signaling protein
Chain: A: PDB Molecule:chemotaxis protein chey homolog;
PDBTitle: crystal structure of chey mutant t84a of helicobacter pylori
54c2gwrA_



not modelled 99.9 24 PDB header:signaling protein
Chain: A: PDB Molecule:dna-binding response regulator mtra;
PDBTitle: crystal structure of the response regulator protein mtra from2 mycobacterium tuberculosis
55c3hv2B_



not modelled 99.9 18 PDB header:signaling protein
Chain: B: PDB Molecule:response regulator/hd domain protein;
PDBTitle: crystal structure of signal receiver domain of hd domain-2 containing protein from pseudomonas fluorescens pf-5
56d1krwa_



not modelled 99.9 29 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
57d1yioa2



not modelled 99.9 27 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
58d2r25b1



not modelled 99.9 28 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
59c2zayA_



not modelled 99.9 20 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator receiver protein;
PDBTitle: crystal structure of response regulator from desulfuromonas2 acetoxidans
60c1ys7B_



99.9 20 PDB header:transcription regulator
Chain: B: PDB Molecule:transcriptional regulatory protein prra;
PDBTitle: crystal structure of the response regulator protein prra comlexed with2 mg2+
61d1zesa1



not modelled 99.9 25 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
62c2qvgA_



not modelled 99.9 18 PDB header:transferase
Chain: A: PDB Molecule:two component response regulator;
PDBTitle: the crystal structure of a two-component response regulator2 from legionella pneumophila
63c3t6kB_



not modelled 99.9 28 PDB header:signaling protein
Chain: B: PDB Molecule:response regulator receiver;
PDBTitle: crystal structure of a hypothetical response regulator (caur_3799)2 from chloroflexus aurantiacus j-10-fl at 1.86 a resolution
64c3ilhA_



not modelled 99.9 17 PDB header:transcription regulator
Chain: A: PDB Molecule:two component response regulator;
PDBTitle: crystal structure of two component response regulator from cytophaga2 hutchinsonii
65c3i42A_



not modelled 99.9 29 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:response regulator receiver domain protein (chey-
PDBTitle: structure of response regulator receiver domain (chey-like)2 from methylobacillus flagellatus
66d1xhfa1



not modelled 99.9 25 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
67d1i3ca_



not modelled 99.9 19 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
68c3rqiA_



not modelled 99.9 20 PDB header:transcription
Chain: A: PDB Molecule:response regulator protein;
PDBTitle: crystal structure of a response regulator protein from burkholderia2 pseudomallei with a phosphorylated aspartic acid, calcium ion and3 citrate
69c1kgsA_



not modelled 99.9 27 PDB header:dna binding protein
Chain: A: PDB Molecule:dna binding response regulator d;
PDBTitle: crystal structure at 1.50 a of an ompr/phob homolog from thermotoga2 maritima
70c3f6cB_



not modelled 99.9 23 PDB header:dna binding protein
Chain: B: PDB Molecule:positive transcription regulator evga;
PDBTitle: crystal structure of n-terminal domain of positive transcription2 regulator evga from escherichia coli
71c3c3mA_



not modelled 99.9 22 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator receiver protein;
PDBTitle: crystal structure of the n-terminal domain of response regulator2 receiver protein from methanoculleus marisnigri jr1
72d1p2fa2



not modelled 99.9 25 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
73c3q9sA_



not modelled 99.9 22 PDB header:dna binding protein
Chain: A: PDB Molecule:dna-binding response regulator;
PDBTitle: crystal structure of rra(1-215) from deinococcus radiodurans
74c1p2fA_



not modelled 99.9 23 PDB header:transcription
Chain: A: PDB Molecule:response regulator;
PDBTitle: crystal structure analysis of response regulator drrb, a2 thermotoga maritima ompr/phob homolog
75c3lteH_



not modelled 99.9 23 PDB header:transcription
Chain: H: PDB Molecule:response regulator;
PDBTitle: crystal structure of response regulator (signal receiver domain) from2 bermanella marisrubri
76d1mb3a_



not modelled 99.9 29 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
77c2oqrA_



not modelled 99.9 17 PDB header:transcription,signaling protein
Chain: A: PDB Molecule:sensory transduction protein regx3;
PDBTitle: the structure of the response regulator regx3 from mycobacterium2 tuberculosis
78c3hzhA_



not modelled 99.9 17 PDB header:signaling protein
Chain: A: PDB Molecule:chemotaxis response regulator (chey-3);
PDBTitle: crystal structure of the chex-chey-bef3-mg+2 complex from2 borrelia burgdorferi
79c3mmnA_



not modelled 99.9 25 PDB header:transferase
Chain: A: PDB Molecule:histidine kinase homolog;
PDBTitle: crystal structure of the receiver domain of the histidine kinase cki12 from arabidopsis thaliana complexed with mg2+
80c3m6mF_



not modelled 99.9 29 PDB header:lyase/transferase
Chain: F: PDB Molecule:sensory/regulatory protein rpfc;
PDBTitle: crystal structure of rpff complexed with rec domain of rpfc
81c3n0rA_



not modelled 99.9 21 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator;
PDBTitle: structure of the phyr stress response regulator at 1.25 angstrom2 resolution
82c2jk1A_



not modelled 99.9 17 PDB header:dna-binding
Chain: A: PDB Molecule:hydrogenase transcriptional regulatory protein hupr1;
PDBTitle: crystal structure of the wild-type hupr receiver domain
83c3kcnA_



not modelled 99.9 20 PDB header:lyase
Chain: A: PDB Molecule:adenylate cyclase homolog;
PDBTitle: the crystal structure of adenylate cyclase from2 rhodopirellula baltica
84c3a0rB_



not modelled 99.9 31 PDB header:transferase
Chain: B: PDB Molecule:response regulator;
PDBTitle: crystal structure of histidine kinase thka (tm1359) in complex with2 response regulator protein trra (tm1360)
85d1k68a_



not modelled 99.9 15 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
86c3grcD_



not modelled 99.9 23 PDB header:transferase
Chain: D: PDB Molecule:sensor protein, kinase;
PDBTitle: crystal structure of a sensor protein from polaromonas sp.2 js666
87c2qxyB_



not modelled 99.9 20 PDB header:transcription
Chain: B: PDB Molecule:response regulator;
PDBTitle: crystal structure of a response regulator from thermotoga2 maritima
88c3eqzB_



not modelled 99.9 21 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:response regulator;
PDBTitle: crystal structure of a response regulator from colwellia2 psychrerythraea
89c3cg4A_



not modelled 99.9 24 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:response regulator receiver domain protein (chey-like);
PDBTitle: crystal structure of response regulator receiver domain protein (chey-2 like) from methanospirillum hungatei jf-1
90c3hdvB_



not modelled 99.9 25 PDB header:transcription regulator
Chain: B: PDB Molecule:response regulator;
PDBTitle: crystal structure of response regulator receiver protein from2 pseudomonas putida
91c2rdmB_



not modelled 99.9 18 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:response regulator receiver protein;
PDBTitle: crystal structure of response regulator receiver protein from2 sinorhizobium medicae wsm419
92c3gl9B_



not modelled 99.9 26 PDB header:signaling protein
Chain: B: PDB Molecule:response regulator;
PDBTitle: the structure of a histidine kinase-response regulator2 complex sheds light into two-component signaling and3 reveals a novel cis autophosphorylation mechanism
93c3nhmA_



not modelled 99.8 25 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator;
PDBTitle: crystal structure of a response regulator from myxococcus xanthus
94d1w25a2



not modelled 99.8 20 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
95c3snkA_



not modelled 99.8 17 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator chey-like protein;
PDBTitle: crystal structure of a response regulator chey-like protein (mll6475)2 from mesorhizobium loti at 2.02 a resolution
96c3h5iA_



not modelled 99.8 20 PDB header:transcription
Chain: A: PDB Molecule:response regulator/sensory box protein/ggdef
PDBTitle: crystal structure of the n-terminal domain of a response2 regulator/sensory box/ggdef 3-domain protein from3 carboxydothermus hydrogenoformans
97c2qsjB_



not modelled 99.8 19 PDB header:transcription
Chain: B: PDB Molecule:dna-binding response regulator, luxr family;
PDBTitle: crystal structure of a luxr family dna-binding response2 regulator from silicibacter pomeroyi
98c3luaA_



not modelled 99.8 23 PDB header:transcription regulator
Chain: A: PDB Molecule:response regulator receiver protein;
PDBTitle: crystal structure of a signal receiver domain of two component signal2 transduction (histidine kinase) from clostridium thermocellum
99d2b4aa1



not modelled 99.8 20 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
100c3c97A_



not modelled 99.8 25 PDB header:signaling protein, transferase
Chain: A: PDB Molecule:signal transduction histidine kinase;
PDBTitle: crystal structure of the response regulator receiver domain2 of a signal transduction histidine kinase from aspergillus3 oryzae
101c1zn2A_



not modelled 99.8 28 PDB header:transcription regulator
Chain: A: PDB Molecule:response regulatory protein;
PDBTitle: low resolution structure of response regulator styr
102c2hqoA_



not modelled 99.8 16 PDB header:signaling protein
Chain: A: PDB Molecule:putative transcriptional regulator;
PDBTitle: structure of a atypical orphan response regulator protein revealed a2 new phosphorylation-independent regulatory mechanism
103c2j48A_



not modelled 99.8 21 PDB header:transferase
Chain: A: PDB Molecule:two-component sensor kinase;
PDBTitle: nmr structure of the pseudo-receiver domain of the cika2 protein.
104d1dcfa_



not modelled 99.8 23 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:Receiver domain of the ethylene receptor
105c2hqrA_



not modelled 99.8 12 PDB header:signaling protein
Chain: A: PDB Molecule:putative transcriptional regulator;
PDBTitle: structure of a atypical orphan response regulator protein revealed a2 new phosphorylation-independent regulatory mechanism
106c3eodA_



not modelled 99.8 24 PDB header:signaling protein
Chain: A: PDB Molecule:protein hnr;
PDBTitle: crystal structure of n-terminal domain of e. coli rssb
107c2nt3A_



not modelled 99.8 22 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator homolog;
PDBTitle: receiver domain from myxococcus xanthus social motility protein frzs2 (y102a mutant)
108c3kyiB_



not modelled 99.8 25 PDB header:transferase
Chain: B: PDB Molecule:chey6 protein;
PDBTitle: crystal structure of the phosphorylated p1 domain of chea3 in complex2 with chey6 from r. sphaeroides
109c3ktoA_



not modelled 99.8 16 PDB header:transcription regulator
Chain: A: PDB Molecule:response regulator receiver protein;
PDBTitle: crystal structure of response regulator receiver protein2 from pseudoalteromonas atlantica
110c3lufB_



not modelled 99.8 21 PDB header:signaling protein
Chain: B: PDB Molecule:two-component system response regulator/ggdef
PDBTitle: structure of probable two-component system response2 regulator/ggdef domain protein
111c3c3wB_



not modelled 99.8 30 PDB header:transcription
Chain: B: PDB Molecule:two component transcriptional regulatory protein devr;
PDBTitle: crystal structure of the mycobacterium tuberculosis hypoxic response2 regulator dosr
112d1qo0d_



not modelled 99.8 18 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:Positive regulator of the amidase operon AmiR
113c3n53B_



not modelled 99.8 30 PDB header:transcription
Chain: B: PDB Molecule:response regulator receiver modulated diguanylate cyclase;
PDBTitle: crystal structure of a response regulator receiver modulated2 diguanylate cyclase from pelobacter carbinolicus
114c1rnlA_



not modelled 99.7 32 PDB header:signal transduction protein
Chain: A: PDB Molecule:nitrate/nitrite response regulator protein narl;
PDBTitle: the nitrate/nitrite response regulator protein narl from narl
115c2yxbA_



not modelled 99.6 15 PDB header:isomerase
Chain: A: PDB Molecule:coenzyme b12-dependent mutase;
PDBTitle: crystal structure of the methylmalonyl-coa mutase alpha-subunit from2 aeropyrum pernix
116c3d6wA_



not modelled 99.6 24 PDB header:dna binding protein
Chain: A: PDB Molecule:methyl-accepting/dna response regulator;
PDBTitle: lyttr dna-binding domain of putative methyl-accepting/dna response2 regulator from bacillus cereus.
117c3cwoX_



not modelled 99.6 20 PDB header:de novo protein
Chain: X: PDB Molecule:beta/alpha-barrel protein based on 1thf and 1tmy;
PDBTitle: a beta/alpha-barrel built by the combination of fragments2 from different folds
118c3bs1A_



not modelled 99.4 18 PDB header:transcription regulator
Chain: A: PDB Molecule:accessory gene regulator protein a;
PDBTitle: structure of the staphylococcus aureus agra lyttr domain2 bound to dna reveals a beta fold with a novel mode of3 binding
119d1fmfa_



not modelled 99.2 9 Fold:Flavodoxin-like
Superfamily:Cobalamin (vitamin B12)-binding domain
Family:Cobalamin (vitamin B12)-binding domain
120c3klnC_



not modelled 99.0 11 PDB header:transcription
Chain: C: PDB Molecule:transcriptional regulator, luxr family;
PDBTitle: vibrio cholerae vpst