Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	V	T	F	E	Q	L	K	A	A	F	N	R	V	L	I	S	R	G	V	D	S	E	T	A	D	A	C	A	E	M	F	A	R	T	T	E	S	G	V	Y	S	H	G	V	N	R	F	P	R	F	I	Q	Q	L	E	N	G	D
Secondary structure
SS confidence
Disorder		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	I	P	D	A	Q	P	K	R	I	T	S	L	G	A	I	E	Q	W	D	A	Q	R	S	I	G	N	L	T	A	K	K	M	M	D	R	A	I	E	L	A	A	D	H	G	I	G	L	V	A	L	R	N	A	N	H	W	M	R	G
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	S	Y	G	W	Q	A	A	E	K	G	Y	I	G	I	C	W	T	N	S	I	A	V	M	P	P	W	G	A	K	E	C	R	I	G	T	N	P	L	I	V	A	I	P	S	T	P	I	T	M	V	D	M	S	M	S	M	F	S	Y
Secondary structure
SS confidence
Disorder																																																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	M	L	E	V	N	R	L	A	G	R	Q	L	P	V	D	G	G	F	D	D	E	G	N	L	T	K	E	P	G	V	I	E	K	N	R	R	I	L	P	M	G	Y	W	K	G	S	G	M	S	I	V	L	D	M	I	A	T	L	L
Secondary structure
SS confidence
Disorder										?																																																			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		S	D	G	A	S	V	A	E	V	T	Q	D	N	S	D	E	Y	G	I	S	Q	I	F	I	A	I	E	V	D	K	L	I	D	G	P	T	R	D	A	K	L	Q	R	I	M	D	Y	V	T	S	A	E	R	A	D	E	N	Q	A	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?		?	?	?	?																			?																							?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.
Sequence		R	L	P	G	H	E	F	T	T	L	L	A	E	N	R	R	N	G	I	T	V	D	D	S	V	W	A	K	I	Q	A	L
Secondary structure
SS confidence
Disorder																		?	?		?											?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1nxu chain A Region: 1 - 332 Aligned: 332 Modelled: 331 Confidence: 100.0% Identity: 95% Fold: L-sulfolactate dehydrogenase-like Superfamily: L-sulfolactate dehydrogenase-like Family: L-sulfolactate dehydrogenase-like Phyre2 PDB 1vbi chain A Region: 1 - 332 Aligned: 328 Modelled: 329 Confidence: 100.0% Identity: 24% PDB header:oxidoreductase Chain: A: PDB Molecule:type 2 malate/lactate dehydrogenase; PDBTitle: crystal structure of type 2 malate/lactate dehydrogenase from thermus2 thermophilus hb8 Phyre2 PDB 1xrh chain A Region: 2 - 332 Aligned: 328 Modelled: 331 Confidence: 100.0% Identity: 22% Fold: L-sulfolactate dehydrogenase-like Superfamily: L-sulfolactate dehydrogenase-like Family: L-sulfolactate dehydrogenase-like Phyre2 PDB 3i0p chain A Region: 1 - 332 Aligned: 332 Modelled: 332 Confidence: 100.0% Identity: 24% PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of malate dehydrogenase from entamoeba histolytica Phyre2 PDB 1z2i chain A Region: 1 - 332 Aligned: 328 Modelled: 332 Confidence: 100.0% Identity: 27% PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of agrobacterium tumefaciens malate2 dehydrogenase, new york structural genomics consortium Phyre2 PDB 1rfm chain A Region: 3 - 332 Aligned: 326 Modelled: 330 Confidence: 100.0% Identity: 27% Fold: L-sulfolactate dehydrogenase-like Superfamily: L-sulfolactate dehydrogenase-like Family: L-sulfolactate dehydrogenase-like Phyre2 PDB 1wtj chain B Region: 1 - 332 Aligned: 325 Modelled: 332 Confidence: 100.0% Identity: 26% PDB header:oxidoreductase Chain: B: PDB Molecule:ureidoglycolate dehydrogenase; PDBTitle: crystal structure of delta1-piperideine-2-carboxylate2 reductase from pseudomonas syringae pvar.tomato Phyre2 PDB 2g8y chain B Region: 2 - 332 Aligned: 329 Modelled: 331 Confidence: 100.0% Identity: 24% PDB header:oxidoreductase Chain: B: PDB Molecule:malate/l-lactate dehydrogenases; PDBTitle: the structure of a putative malate/lactate dehydrogenase from e. coli. Phyre2 PDB 1v9n chain A Region: 1 - 332 Aligned: 320 Modelled: 332 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: structure of malate dehydrogenase from pyrococcus horikoshii ot3 Phyre2 PDB 3uoe chain B Region: 2 - 332 Aligned: 311 Modelled: 313 Confidence: 100.0% Identity: 24% PDB header:oxidoreductase Chain: B: PDB Molecule:dehydrogenase; PDBTitle: the crystal structure of dehydrogenase from sinorhizobium meliloti Phyre2 PDB 3eef chain A Region: 73 - 116 Aligned: 44 Modelled: 44 Confidence: 49.9% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein; PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum Phyre2 PDB 2qiw chain A Region: 11 - 116 Aligned: 87 Modelled: 106 Confidence: 48.9% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:pep phosphonomutase; PDBTitle: crystal structure of a putative phosphoenolpyruvate phosphonomutase2 (ncgl1015, cgl1060) from corynebacterium glutamicum atcc 13032 at3 1.80 a resolution Phyre2 PDB 3irv chain A Region: 62 - 116 Aligned: 55 Modelled: 55 Confidence: 46.7% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:cysteine hydrolase; PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a Phyre2 PDB 3kl2 chain K Region: 72 - 116 Aligned: 45 Modelled: 45 Confidence: 46.2% Identity: 11% PDB header:structural genomics, unknown function Chain: K: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis Phyre2 PDB 2ze3 chain A Region: 11 - 116 Aligned: 90 Modelled: 105 Confidence: 42.9% Identity: 21% PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus Phyre2 PDB 1mum chain A Region: 11 - 118 Aligned: 91 Modelled: 107 Confidence: 41.7% Identity: 11% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Phosphoenolpyruvate mutase/Isocitrate lyase-like Phyre2 PDB 2hjp chain A Region: 11 - 116 Aligned: 89 Modelled: 103 Confidence: 38.3% Identity: 8% PDB header:hydrolase Chain: A: PDB Molecule:phosphonopyruvate hydrolase; PDBTitle: crystal structure of phosphonopyruvate hydrolase complex with2 phosphonopyruvate and mg++ Phyre2 PDB 1nba chain A Region: 73 - 116 Aligned: 44 Modelled: 44 Confidence: 37.7% Identity: 20% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 2ebf chain X domain 2 Region: 33 - 130 Aligned: 67 Modelled: 69 Confidence: 37.3% Identity: 25% Fold: EreA/ChaN-like Superfamily: EreA/ChaN-like Family: PMT domain-like Phyre2 PDB 3b8i chain F Region: 11 - 111 Aligned: 85 Modelled: 88 Confidence: 37.3% Identity: 14% PDB header:lyase Chain: F: PDB Molecule:pa4872 oxaloacetate decarboxylase; PDBTitle: crystal structure of oxaloacetate decarboxylase from pseudomonas2 aeruginosa (pa4872) in complex with oxalate and mg2+. Phyre2 1 d1nxua_ 2 c1vbiA_ 3 d1xrha_ 4 c3i0pA_ 5 c1z2iA_ 6 d1rfma_ 7 c1wtjB_ 8 c2g8yB_ 9 c1v9nA_ 10 c3uoeB_ 11 c3eefA_ 12 c2qiwA_ 13 c3irvA_ 14 c3kl2K_ 15 c2ze3A_ 16 d1muma_ 17 c2hjpA_ 18 d1nbaa_ 19 d2ebfx2 20 c3b8iF_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1nxua_ 100.0 95 Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like 2 c1vbiA_ 100.0 24 PDB header:oxidoreductase Chain: A: PDB Molecule:type 2 malate/lactate dehydrogenase; PDBTitle: crystal structure of type 2 malate/lactate dehydrogenase from thermus2 thermophilus hb8 3 d1xrha_ 100.0 22 Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like 4 c3i0pA_ 100.0 24 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of malate dehydrogenase from entamoeba histolytica 5 c1z2iA_ 100.0 27 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of agrobacterium tumefaciens malate2 dehydrogenase, new york structural genomics consortium 6 d1rfma_ 100.0 27 Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like 7 c1wtjB_ 100.0 26 PDB header:oxidoreductase Chain: B: PDB Molecule:ureidoglycolate dehydrogenase; PDBTitle: crystal structure of delta1-piperideine-2-carboxylate2 reductase from pseudomonas syringae pvar.tomato 8 c2g8yB_ 100.0 24 PDB header:oxidoreductase Chain: B: PDB Molecule:malate/l-lactate dehydrogenases; PDBTitle: the structure of a putative malate/lactate dehydrogenase from e. coli. 9 c1v9nA_ 100.0 28 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: structure of malate dehydrogenase from pyrococcus horikoshii ot3 10 c3uoeB_ 100.0 24 PDB header:oxidoreductase Chain: B: PDB Molecule:dehydrogenase; PDBTitle: the crystal structure of dehydrogenase from sinorhizobium meliloti 11 c3eefA_ 49.9 16 PDB header:hydrolase Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein; PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum 12 c2qiwA_ 48.9 13 PDB header:transferase Chain: A: PDB Molecule:pep phosphonomutase; PDBTitle: crystal structure of a putative phosphoenolpyruvate phosphonomutase2 (ncgl1015, cgl1060) from corynebacterium glutamicum atcc 13032 at3 1.80 a resolution 13 c3irvA_ 46.7 13 PDB header:hydrolase Chain: A: PDB Molecule:cysteine hydrolase; PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a 14 c3kl2K_ 46.2 11 PDB header:structural genomics, unknown function Chain: K: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis 15 c2ze3A_ 42.9 21 PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus 16 d1muma_ 41.7 11 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 17 c2hjpA_ 38.3 8 PDB header:hydrolase Chain: A: PDB Molecule:phosphonopyruvate hydrolase; PDBTitle: crystal structure of phosphonopyruvate hydrolase complex with2 phosphonopyruvate and mg++ 18 d1nbaa_ 37.7 20 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 19 d2ebfx2 37.3 25 Fold:EreA/ChaN-like Superfamily:EreA/ChaN-like Family:PMT domain-like 20 c3b8iF_ 37.3 14 PDB header:lyase Chain: F: PDB Molecule:pa4872 oxaloacetate decarboxylase; PDBTitle: crystal structure of oxaloacetate decarboxylase from pseudomonas2 aeruginosa (pa4872) in complex with oxalate and mg2+. 21 c2b34C_ not modelled 37.3 17 PDB header:hydrolase Chain: C: PDB Molecule:mar1 ribonuclease; PDBTitle: structure of mar1 ribonuclease from caenorhabditis elegans 22 d1nf9a_ not modelled 37.2 11 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 23 c3ih1A_ not modelled 36.2 13 PDB header:lyase Chain: A: PDB Molecule:methylisocitrate lyase; PDBTitle: crystal structure of carboxyvinyl-carboxyphosphonate phosphorylmutase2 from bacillus anthracis 24 c3ot4F_ not modelled 35.7 11 PDB header:hydrolase Chain: F: PDB Molecule:putative isochorismatase; PDBTitle: structure and catalytic mechanism of bordetella bronchiseptica nicf 25 c3eooL_ not modelled 31.8 13 PDB header:lyase Chain: L: PDB Molecule:methylisocitrate lyase; PDBTitle: 2.9a crystal structure of methyl-isocitrate lyase from2 burkholderia pseudomallei 26 c1e0mA_ not modelled 28.8 21 PDB header:de novo protein Chain: A: PDB Molecule:wwprototype; PDBTitle: prototype ww domain 27 c1yiuA_ not modelled 27.4 29 PDB header:ligase Chain: A: PDB Molecule:itchy e3 ubiquitin protein ligase; PDBTitle: itch e3 ubiquitin ligase ww3 domain 28 c2ysbA_ not modelled 25.9 18 PDB header:protein binding Chain: A: PDB Molecule:salvador homolog 1 protein; PDBTitle: solution structure of the first ww domain from the mouse2 salvador homolog 1 protein (sav1) 29 d1wdjb_ not modelled 25.4 10 Fold:Restriction endonuclease-like Superfamily:Restriction endonuclease-like Family:Hypothetical protein TT1808 (TTHA1514) 30 c3mcwA_ not modelled 25.3 14 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of an a putative hydrolase of the isochorismatase2 family (cv_1320) from chromobacterium violaceum atcc 12472 at 1.06 a3 resolution 31 c3l4hA_ not modelled 25.2 17 PDB header:protein binding Chain: A: PDB Molecule:e3 ubiquitin-protein ligase hecw1; PDBTitle: helical box domain and second ww domain of the human e3 ubiquitin-2 protein ligase hecw1 32 c3hb7G_ not modelled 24.6 16 PDB header:hydrolase Chain: G: PDB Molecule:isochorismatase hydrolase; PDBTitle: the crystal structure of an isochorismatase-like hydrolase from2 alkaliphilus metalliredigens to 2.3a 33 d1wdja_ not modelled 23.9 10 Fold:Restriction endonuclease-like Superfamily:Restriction endonuclease-like Family:Hypothetical protein TT1808 (TTHA1514) 34 c2px0D_ not modelled 23.0 10 PDB header:biosynthetic protein Chain: D: PDB Molecule:flagellar biosynthesis protein flhf; PDBTitle: crystal structure of flhf complexed with gmppnp/mg(2+) 35 c2ysdA_ not modelled 22.9 20 PDB header:protein binding Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz PDBTitle: solution structure of the first ww domain from the human2 membrane-associated guanylate kinase, ww and pdz domain-3 containing protein 1. magi-1 36 d1f8ab1 not modelled 22.8 20 Fold:WW domain-like Superfamily:WW domain Family:WW domain 37 d1yaca_ not modelled 22.4 15 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 38 c1wr7A_ not modelled 22.2 20 PDB header:ligase Chain: A: PDB Molecule:nedd4-2; PDBTitle: solution structure of the third ww domain of nedd4-2 39 c2fq1A_ not modelled 21.6 9 PDB header:hydrolase Chain: A: PDB Molecule:isochorismatase; PDBTitle: crystal structure of the two-domain non-ribosomal peptide synthetase2 entb containing isochorismate lyase and aryl-carrier protein domains 40 d1sgma2 not modelled 21.4 25 Fold:Tetracyclin repressor-like, C-terminal domain Superfamily:Tetracyclin repressor-like, C-terminal domain Family:Tetracyclin repressor-like, C-terminal domain 41 c2djyA_ not modelled 21.4 21 PDB header:ligase/signaling protein Chain: A: PDB Molecule:smad ubiquitination regulatory factor 2; PDBTitle: solution structure of smurf2 ww3 domain-smad7 py peptide2 complex 42 c3ot2A_ not modelled 21.2 10 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a putative nuclease belonging to duf8202 (ava_3926) from anabaena variabilis atcc 29413 at 1.96 a resolution 43 c3ot2B_ not modelled 21.2 10 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a putative nuclease belonging to duf8202 (ava_3926) from anabaena variabilis atcc 29413 at 1.96 a resolution 44 d1t57a_ not modelled 20.9 16 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:MTH1675-like 45 c1wr4A_ not modelled 20.7 29 PDB header:ligase Chain: A: PDB Molecule:ubiquitin-protein ligase nedd4-2; PDBTitle: solution structure of the second ww domain of nedd4-2 46 d1bdga1 not modelled 20.5 16 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Hexokinase 47 c2lawA_ not modelled 20.4 21 PDB header:signaling protein/transcription Chain: A: PDB Molecule:yorkie homolog; PDBTitle: structure of the second ww domain from human yap in complex with a2 human smad1 derived peptide 48 c3oqpA_ not modelled 20.3 24 PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution 49 c1wmvA_ not modelled 20.3 29 PDB header:oxidoreductase, apoptosis Chain: A: PDB Molecule:ww domain containing oxidoreductase; PDBTitle: solution structure of the second ww domain of wwox 50 c2uygF_ not modelled 20.0 20 PDB header:lyase Chain: F: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystallogaphic structure of the typeii 3-dehydroquinase2 from thermus thermophilus 51 d1k9ra_ not modelled 19.8 18 Fold:WW domain-like Superfamily:WW domain Family:WW domain 52 c2h0rD_ not modelled 19.5 14 PDB header:hydrolase Chain: D: PDB Molecule:nicotinamidase; PDBTitle: structure of the yeast nicotinamidase pnc1p 53 d2cfua2 not modelled 19.5 14 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Alkylsulfatase-like 54 d3bzra1 not modelled 19.4 13 Fold:EscU C-terminal domain-like Superfamily:EscU C-terminal domain-like Family:EscU C-terminal domain-like 55 c3bzrA_ not modelled 19.4 13 PDB header:membrane protein, protein transport Chain: A: PDB Molecule:escu; PDBTitle: crystal structure of escu c-terminal domain with n262d mutation, space2 group p 41 21 2 56 c3t7yB_ not modelled 19.0 16 PDB header:protein transport Chain: B: PDB Molecule:yop proteins translocation protein u; PDBTitle: structure of an autocleavage-inactive mutant of the cytoplasmic domain2 of ct091, the yscu homologue of chlamydia trachomatis 57 d3ci0k2 not modelled 18.6 15 Fold:SAM domain-like Superfamily:GspK insert domain-like Family:GspK insert domain-like 58 d1tk7a1 not modelled 18.3 14 Fold:WW domain-like Superfamily:WW domain Family:WW domain 59 c1ymzA_ not modelled 18.1 36 PDB header:unknown function Chain: A: PDB Molecule:cc45; PDBTitle: cc45, an artificial ww domain designed using statistical2 coupling analysis 60 d1j2ra_ not modelled 17.0 14 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 61 c2k29A_ not modelled 16.5 33 PDB header:transcription Chain: A: PDB Molecule:antitoxin relb; PDBTitle: structure of the dbd domain of e. coli antitoxin relb 62 d1i5hw_ not modelled 16.5 20 Fold:WW domain-like Superfamily:WW domain Family:WW domain 63 d1f61a_ not modelled 16.0 17 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 64 d3djba1 not modelled 15.6 14 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 65 c3lqyA_ not modelled 15.3 18 PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase hydrolase; PDBTitle: crystal structure of putative isochorismatase hydrolase from2 oleispira antarctica 66 c2kxqA_ not modelled 14.2 20 PDB header:protein binding Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf2; PDBTitle: solution structure of smurf2 ww2 and ww3 bound to smad7 py motif2 containing peptide 67 d1mnta_ not modelled 14.0 19 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:Arc/Mnt-like phage repressors 68 d1a4sa_ not modelled 13.9 18 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 69 c2jlhA_ not modelled 13.7 16 PDB header:protein transport Chain: A: PDB Molecule:yop proteins translocation protein u; PDBTitle: crystal structure of the cytoplasmic domain of yersinia2 pestis yscu n263a mutant 70 c3o93A_ not modelled 13.0 14 PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: high resolution crystal structures of streptococcus pneumoniae2 nicotinamidase with trapped intermediates provide insights into3 catalytic mechanism and inhibition by aldehydes 71 c3hu5B_ not modelled 13.0 15 PDB header:hydrolase Chain: B: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein from desulfovibrio2 vulgaris subsp. vulgaris str. hildenborough 72 c3oqpB_ not modelled 12.9 24 PDB header:hydrolase Chain: B: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution 73 c3ivlA_ not modelled 12.8 12 PDB header:hydrolase Chain: A: PDB Molecule:putative zinc protease; PDBTitle: the crystal structure of the inactive peptidase domain of a putative2 zinc protease from bordetella parapertussis to 2.2a 74 c2hg2A_ not modelled 12.7 18 PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase a; PDBTitle: structure of lactaldehyde dehydrogenase 75 c3fpvC_ not modelled 12.6 21 PDB header:heme binding protein Chain: C: PDB Molecule:extracellular haem-binding protein; PDBTitle: crystal structure of hbps 76 d1lvaa3 not modelled 12.5 11 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:C-terminal fragment of elongation factor SelB 77 d1zk8a2 not modelled 12.5 21 Fold:Tetracyclin repressor-like, C-terminal domain Superfamily:Tetracyclin repressor-like, C-terminal domain Family:Tetracyclin repressor-like, C-terminal domain 78 c3le4A_ not modelled 12.1 22 PDB header:nuclear protein Chain: A: PDB Molecule:microprocessor complex subunit dgcr8; PDBTitle: crystal structure of the dgcr8 dimerization domain 79 c2dmvA_ not modelled 11.9 27 PDB header:ligase Chain: A: PDB Molecule:itchy homolog e3 ubiquitin protein ligase; PDBTitle: solution structure of the second ww domain of itchy homolog2 e3 ubiquitin protein ligase (itch) 80 c2h6rG_ not modelled 11.8 18 PDB header:isomerase Chain: G: PDB Molecule:triosephosphate isomerase; PDBTitle: crystal structure of triosephosphate isomerase (tim) from2 methanocaldococcus jannaschii 81 c2dclB_ not modelled 11.8 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical upf0166 protein ph1503; PDBTitle: structure of ph1503 protein from pyrococcus horikoshii ot3 82 c3ju8B_ not modelled 11.6 33 PDB header:oxidoreductase Chain: B: PDB Molecule:succinylglutamic semialdehyde dehydrogenase; PDBTitle: crystal structure of succinylglutamic semialdehyde dehydrogenase from2 pseudomonas aeruginosa. 83 c2a67C_ not modelled 11.4 14 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein 84 c2cfuA_ not modelled 11.4 14 PDB header:hydrolase Chain: A: PDB Molecule:sdsa1; PDBTitle: crystal structure of sdsa1, an alkylsulfatase from2 pseudomonas aeruginosa, in complex with 1-decane-sulfonic-3 acid. 85 c3k2wD_ not modelled 11.3 20 PDB header:oxidoreductase Chain: D: PDB Molecule:betaine-aldehyde dehydrogenase; PDBTitle: crystal structure of betaine-aldehyde dehydrogenase from2 pseudoalteromonas atlantica t6c 86 d2jmfa1 not modelled 11.3 21 Fold:WW domain-like Superfamily:WW domain Family:WW domain 87 d1o51a_ not modelled 10.6 14 Fold:Ferredoxin-like Superfamily:GlnB-like Family:DUF190/COG1993 88 c2xetB_ not modelled 10.5 5 PDB header:transport protein Chain: B: PDB Molecule:f1 capsule-anchoring protein; PDBTitle: conserved hydrophobic clusters on the surface of the caf1a usher2 c-terminal domain are important for f1 antigen assembly 89 c3e0kA_ not modelled 10.5 8 PDB header:transferase Chain: A: PDB Molecule:amino-acid acetyltransferase; PDBTitle: crystal structure of c-termianl domain of n-acetylglutamate synthase2 from vibrio parahaemolyticus 90 d2bfda1 not modelled 10.5 11 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Branched-chain alpha-keto acid dehydrogenase PP module 91 c2vovA_ not modelled 10.4 38 PDB header:metal-binding protein Chain: A: PDB Molecule:surface-associated protein; PDBTitle: an oxidized tryptophan facilitates copper-binding in2 methylococcus capsulatus secreted protein mope. the3 stucture of wild-type mope to 1.35aa 92 c3jz4C_ not modelled 10.3 26 PDB header:oxidoreductase Chain: C: PDB Molecule:succinate-semialdehyde dehydrogenase [nadp+]; PDBTitle: crystal structure of e. coli nadp dependent enzyme 93 c3iwkB_ not modelled 10.3 25 PDB header:oxidoreductase Chain: B: PDB Molecule:aminoaldehyde dehydrogenase; PDBTitle: crystal structure of aminoaldehyde dehydrogenase 1 from2 pisum sativum (psamadh1) 94 d1vp8a_ not modelled 10.3 19 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:MTH1675-like 95 c1qzrA_ not modelled 10.3 10 PDB header:isomerase Chain: A: PDB Molecule:dna topoisomerase ii; PDBTitle: crystal structure of the atpase region of saccharomyces cerevisiae2 topoisomerase ii bound to icrf-187 (dexrazoxane) 96 c3hazA_ not modelled 10.1 21 PDB header:oxidoreductase Chain: A: PDB Molecule:proline dehydrogenase; PDBTitle: crystal structure of bifunctional proline utilization a2 (puta) protein 97 d1nnsa_ not modelled 10.0 14 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 98 d2pw9a1 not modelled 10.0 26 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:FdhD/NarQ 99 d1ig8a1 not modelled 10.0 22 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Hexokinase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0