Phyre 2 Results for P37672

Phyre Home | Retrieve Phyre Job Id

Email | l.a.kelley@imperial.ac.uk
Description | P37672
Date | Thu Jan 5 11:56:44 GMT 2012
Unique Job ID | 46ce4fcc1dc425cd

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template d1nxua_
Top template information
Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like
Confidence and coverage
Confidence: | 100.0% | Coverage: | 100%
332 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | K | V | T | F | E | Q | L | K | A | A | F | N | R | V | L | I | S | R | G | V | D | S | E | T | A | D | A | C | A | E | M | F | A | R | T | T | E | S | G | V | Y | S | H | G | V | N | R | F | P | R | F | I | Q | Q | L | E | N | G | D
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | I | I | P | D | A | Q | P | K | R | I | T | S | L | G | A | I | E | Q | W | D | A | Q | R | S | I | G | N | L | T | A | K | K | M | M | D | R | A | I | E | L | A | A | D | H | G | I | G | L | V | A | L | R | N | A | N | H | W | M | R | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | G | S | Y | G | W | Q | A | A | E | K | G | Y | I | G | I | C | W | T | N | S | I | A | V | M | P | P | W | G | A | K | E | C | R | I | G | T | N | P | L | I | V | A | I | P | S | T | P | I | T | M | V | D | M | S | M | S | M | F | S | Y
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | G | M | L | E | V | N | R | L | A | G | R | Q | L | P | V | D | G | G | F | D | D | E | G | N | L | T | K | E | P | G | V | I | E | K | N | R | R | I | L | P | M | G | Y | W | K | G | S | G | M | S | I | V | L | D | M | I | A | T | L | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | S | D | G | A | S | V | A | E | V | T | Q | D | N | S | D | E | Y | G | I | S | Q | I | F | I | A | I | E | V | D | K | L | I | D | G | P | T | R | D | A | K | L | Q | R | I | M | D | Y | V | T | S | A | E | R | A | D | E | N | Q | A | I
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | .
Sequence |  | R | L | P | G | H | E | F | T | T | L | L | A | E | N | R | R | N | G | I | T | V | D | D | S | V | W | A | K | I | Q | A | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  | ? |  |  |  |  |  |  |  |  |  |  | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| d1nxua_ |

### PDB 1nxu chain A

Region: 1 - 332
Aligned: 332
Modelled: 331
Confidence: 100.0%
Identity: 95%
Fold: L-sulfolactate dehydrogenase-like
Superfamily: L-sulfolactate dehydrogenase-like
Family: L-sulfolactate dehydrogenase-like

Phyre2
2 |
| c1vbiA_ |

### PDB 1vbi chain A

Region: 1 - 332
Aligned: 328
Modelled: 329
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: A: PDB Molecule:type 2 malate/lactate dehydrogenase;
PDBTitle: crystal structure of type 2 malate/lactate dehydrogenase from thermus2 thermophilus hb8

Phyre2
3 |
| d1xrha_ |

### PDB 1xrh chain A

Region: 2 - 332
Aligned: 328
Modelled: 331
Confidence: 100.0%
Identity: 22%
Fold: L-sulfolactate dehydrogenase-like
Superfamily: L-sulfolactate dehydrogenase-like
Family: L-sulfolactate dehydrogenase-like

Phyre2
4 |
| c3i0pA_ |

### PDB 3i0p chain A

Region: 1 - 332
Aligned: 332
Modelled: 332
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: A: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of malate dehydrogenase from entamoeba histolytica

Phyre2
5 |
| c1z2iA_ |

### PDB 1z2i chain A

Region: 1 - 332
Aligned: 328
Modelled: 332
Confidence: 100.0%
Identity: 27%
PDB header:oxidoreductase
Chain: A: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of agrobacterium tumefaciens malate2 dehydrogenase, new york structural genomics consortium

Phyre2
6 |
| d1rfma_ |

### PDB 1rfm chain A

Region: 3 - 332
Aligned: 326
Modelled: 330
Confidence: 100.0%
Identity: 27%
Fold: L-sulfolactate dehydrogenase-like
Superfamily: L-sulfolactate dehydrogenase-like
Family: L-sulfolactate dehydrogenase-like

Phyre2
7 |
| c1wtjB_ |

### PDB 1wtj chain B

Region: 1 - 332
Aligned: 325
Modelled: 332
Confidence: 100.0%
Identity: 26%
PDB header:oxidoreductase
Chain: B: PDB Molecule:ureidoglycolate dehydrogenase;
PDBTitle: crystal structure of delta1-piperideine-2-carboxylate2 reductase from pseudomonas syringae pvar.tomato

Phyre2
8 |
| c2g8yB_ |

### PDB 2g8y chain B

Region: 2 - 332
Aligned: 329
Modelled: 331
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: B: PDB Molecule:malate/l-lactate dehydrogenases;
PDBTitle: the structure of a putative malate/lactate dehydrogenase from e. coli.

Phyre2
9 |
| c1v9nA_ |

### PDB 1v9n chain A

Region: 1 - 332
Aligned: 320
Modelled: 332
Confidence: 100.0%
Identity: 28%
PDB header:oxidoreductase
Chain: A: PDB Molecule:malate dehydrogenase;
PDBTitle: structure of malate dehydrogenase from pyrococcus horikoshii ot3

Phyre2
10 |
| c3uoeB_ |

### PDB 3uoe chain B

Region: 2 - 332
Aligned: 311
Modelled: 313
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: B: PDB Molecule:dehydrogenase;
PDBTitle: the crystal structure of dehydrogenase from sinorhizobium meliloti

Phyre2
11 |
| c3eefA_ |

### PDB 3eef chain A

Region: 73 - 116
Aligned: 44
Modelled: 44
Confidence: 49.9%
Identity: 16%
PDB header:hydrolase
Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein;
PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum

Phyre2
12 |
| c2qiwA_ |

### PDB 2qiw chain A

Region: 11 - 116
Aligned: 87
Modelled: 106
Confidence: 48.9%
Identity: 13%
PDB header:transferase
Chain: A: PDB Molecule:pep phosphonomutase;
PDBTitle: crystal structure of a putative phosphoenolpyruvate phosphonomutase2 (ncgl1015, cgl1060) from corynebacterium glutamicum atcc 13032 at3 1.80 a resolution

Phyre2
13 |
| c3irvA_ |

### PDB 3irv chain A

Region: 62 - 116
Aligned: 55
Modelled: 55
Confidence: 46.7%
Identity: 13%
PDB header:hydrolase
Chain: A: PDB Molecule:cysteine hydrolase;
PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a

Phyre2
14 |
| c3kl2K_ |

### PDB 3kl2 chain K

Region: 72 - 116
Aligned: 45
Modelled: 45
Confidence: 46.2%
Identity: 11%
PDB header:structural genomics, unknown function
Chain: K: PDB Molecule:putative isochorismatase;
PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis

Phyre2
15 |
| c2ze3A_ |

### PDB 2ze3 chain A

Region: 11 - 116
Aligned: 90
Modelled: 105
Confidence: 42.9%
Identity: 21%
PDB header:isomerase
Chain: A: PDB Molecule:dfa0005;
PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus

Phyre2
16 |
| d1muma_ |

### PDB 1mum chain A

Region: 11 - 118
Aligned: 91
Modelled: 107
Confidence: 41.7%
Identity: 11%
Fold: TIM beta/alpha-barrel
Superfamily: Phosphoenolpyruvate/pyruvate domain
Family: Phosphoenolpyruvate mutase/Isocitrate lyase-like

Phyre2
17 |
| c2hjpA_ |

### PDB 2hjp chain A

Region: 11 - 116
Aligned: 89
Modelled: 103
Confidence: 38.3%
Identity: 8%
PDB header:hydrolase
Chain: A: PDB Molecule:phosphonopyruvate hydrolase;
PDBTitle: crystal structure of phosphonopyruvate hydrolase complex with2 phosphonopyruvate and mg++

Phyre2
18 |
| d1nbaa_ |

### PDB 1nba chain A

Region: 73 - 116
Aligned: 44
Modelled: 44
Confidence: 37.7%
Identity: 20%
Fold: Isochorismatase-like hydrolases
Superfamily: Isochorismatase-like hydrolases
Family: Isochorismatase-like hydrolases

Phyre2
19 |
| d2ebfx2 |

### PDB 2ebf chain X domain 2

Region: 33 - 130
Aligned: 67
Modelled: 69
Confidence: 37.3%
Identity: 25%
Fold: EreA/ChaN-like
Superfamily: EreA/ChaN-like
Family: PMT domain-like

Phyre2
20 |
| c3b8iF_ |

### PDB 3b8i chain F

Region: 11 - 111
Aligned: 85
Modelled: 88
Confidence: 37.3%
Identity: 14%
PDB header:lyase
Chain: F: PDB Molecule:pa4872 oxaloacetate decarboxylase;
PDBTitle: crystal structure of oxaloacetate decarboxylase from pseudomonas2 aeruginosa (pa4872) in complex with oxalate and mg2+.

Phyre2
21 |
22 |
23 |
24 |
25 |
26 |
27 |
28 |
29 |
30 |
31 |
32 |
33 |
34 |
35 |
36 |
37 |
38 |
39 |
40 |
41 |
42 |
43 |
44 |
45 |
46 |
47 |
48 |
49 |
50 |
51 |
52 |
53 |
54 |
55 |
56 |
57 |
58 |
59 |
60 |
61 |
62 |
63 |
64 |
65 |
66 |
67 |
68 |
69 |
70 |
71 |
72 |
73 |
74 |
75 |
76 |
77 |
78 |
79 |
80 |
81 |
82 |
83 |
84 |
85 |
86 |
87 |
88 |
89 |
90 |
91 |
92 |
93 |
94 |
95 |
96 |
97 |
98 |
99 |

Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | d1nxua_ |
|  | 100.0 | 95 | Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like
2 | c1vbiA_ |
|  | 100.0 | 24 | PDB header:oxidoreductase Chain: A: PDB Molecule:type 2 malate/lactate dehydrogenase; PDBTitle: crystal structure of type 2 malate/lactate dehydrogenase from thermus2 thermophilus hb8
3 | d1xrha_ |
|  | 100.0 | 22 | Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like
4 | c3i0pA_ |
|  | 100.0 | 24 | PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of malate dehydrogenase from entamoeba histolytica
5 | c1z2iA_ |
|  | 100.0 | 27 | PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of agrobacterium tumefaciens malate2 dehydrogenase, new york structural genomics consortium
6 | d1rfma_ |
|  | 100.0 | 27 | Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like
7 | c1wtjB_ |
|  | 100.0 | 26 | PDB header:oxidoreductase Chain: B: PDB Molecule:ureidoglycolate dehydrogenase; PDBTitle: crystal structure of delta1-piperideine-2-carboxylate2 reductase from pseudomonas syringae pvar.tomato
8 | c2g8yB_ |
|  | 100.0 | 24 | PDB header:oxidoreductase Chain: B: PDB Molecule:malate/l-lactate dehydrogenases; PDBTitle: the structure of a putative malate/lactate dehydrogenase from e. coli.
9 | c1v9nA_ |
|  | 100.0 | 28 | PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: structure of malate dehydrogenase from pyrococcus horikoshii ot3
10 | c3uoeB_ |
|  | 100.0 | 24 | PDB header:oxidoreductase Chain: B: PDB Molecule:dehydrogenase; PDBTitle: the crystal structure of dehydrogenase from sinorhizobium meliloti
11 | c3eefA_ |
|  | 49.9 | 16 | PDB header:hydrolase Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein; PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum
12 | c2qiwA_ |
|  | 48.9 | 13 | PDB header:transferase Chain: A: PDB Molecule:pep phosphonomutase; PDBTitle: crystal structure of a putative phosphoenolpyruvate phosphonomutase2 (ncgl1015, cgl1060) from corynebacterium glutamicum atcc 13032 at3 1.80 a resolution
13 | c3irvA_ |
|  | 46.7 | 13 | PDB header:hydrolase Chain: A: PDB Molecule:cysteine hydrolase; PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a
14 | c3kl2K_ |
|  | 46.2 | 11 | PDB header:structural genomics, unknown function Chain: K: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis
15 | c2ze3A_ |
|  | 42.9 | 21 | PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus
16 | d1muma_ |
|  | 41.7 | 11 | Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like
17 | c2hjpA_ |
|  | 38.3 | 8 | PDB header:hydrolase Chain: A: PDB Molecule:phosphonopyruvate hydrolase; PDBTitle: crystal structure of phosphonopyruvate hydrolase complex with2 phosphonopyruvate and mg++
18 | d1nbaa_ |
|  | 37.7 | 20 | Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases
19 | d2ebfx2 |
|  | 37.3 | 25 | Fold:EreA/ChaN-like Superfamily:EreA/ChaN-like Family:PMT domain-like
20 | c3b8iF_ |
|  | 37.3 | 14 | PDB header:lyase Chain: F: PDB Molecule:pa4872 oxaloacetate decarboxylase; PDBTitle: crystal structure of oxaloacetate decarboxylase from pseudomonas2 aeruginosa (pa4872) in complex with oxalate and mg2+.
21 | c2b34C_ |
| not modelled | 37.3 | 17 | PDB header:hydrolase Chain: C: PDB Molecule:mar1 ribonuclease; PDBTitle: structure of mar1 ribonuclease from caenorhabditis elegans
22 | d1nf9a_ |
| not modelled | 37.2 | 11 | Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases
23 | c3ih1A_ |
| not modelled | 36.2 | 13 | PDB header:lyase Chain: A: PDB Molecule:methylisocitrate lyase; PDBTitle: crystal structure of carboxyvinyl-carboxyphosphonate phosphorylmutase2 from bacillus anthracis
24 | c3ot4F_ |
| not modelled | 35.7 | 11 | PDB header:hydrolase Chain: F: PDB Molecule:putative isochorismatase; PDBTitle: structure and catalytic mechanism of bordetella bronchiseptica nicf
25 | c3eooL_ |
| not modelled | 31.8 | 13 | PDB header:lyase Chain: L: PDB Molecule:methylisocitrate lyase; PDBTitle: 2.9a crystal structure of methyl-isocitrate lyase from2 burkholderia pseudomallei
26 | c1e0mA_ |
| not modelled | 28.8 | 21 | PDB header:de novo protein Chain: A: PDB Molecule:wwprototype; PDBTitle: prototype ww domain
27 | c1yiuA_ |
| not modelled | 27.4 | 29 | PDB header:ligase Chain: A: PDB Molecule:itchy e3 ubiquitin protein ligase; PDBTitle: itch e3 ubiquitin ligase ww3 domain
28 | c2ysbA_ |
| not modelled | 25.9 | 18 | PDB header:protein binding Chain: A: PDB Molecule:salvador homolog 1 protein; PDBTitle: solution structure of the first ww domain from the mouse2 salvador homolog 1 protein (sav1)
29 | d1wdjb_ |
| not modelled | 25.4 | 10 | Fold:Restriction endonuclease-like Superfamily:Restriction endonuclease-like Family:Hypothetical protein TT1808 (TTHA1514)
30 | c3mcwA_ |
| not modelled | 25.3 | 14 | PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of an a putative hydrolase of the isochorismatase2 family (cv_1320) from chromobacterium violaceum atcc 12472 at 1.06 a3 resolution
31 | c3l4hA_ |
| not modelled | 25.2 | 17 | PDB header:protein binding Chain: A: PDB Molecule:e3 ubiquitin-protein ligase hecw1; PDBTitle: helical box domain and second ww domain of the human e3 ubiquitin-2 protein ligase hecw1
32 | c3hb7G_ |
| not modelled | 24.6 | 16 | PDB header:hydrolase Chain: G: PDB Molecule:isochorismatase hydrolase; PDBTitle: the crystal structure of an isochorismatase-like hydrolase from2 alkaliphilus metalliredigens to 2.3a
33 | d1wdja_ |
| not modelled | 23.9 | 10 | Fold:Restriction endonuclease-like Superfamily:Restriction endonuclease-like Family:Hypothetical protein TT1808 (TTHA1514)
34 | c2px0D_ |
| not modelled | 23.0 | 10 | PDB header:biosynthetic protein Chain: D: PDB Molecule:flagellar biosynthesis protein flhf; PDBTitle: crystal structure of flhf complexed with gmppnp/mg(2+)
35 | c2ysdA_ |
| not modelled | 22.9 | 20 | PDB header:protein binding Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz PDBTitle: solution structure of the first ww domain from the human2 membrane-associated guanylate kinase, ww and pdz domain-3 containing protein 1. magi-1
36 | d1f8ab1 |
| not modelled | 22.8 | 20 | Fold:WW domain-like Superfamily:WW domain Family:WW domain
37 | d1yaca_ |
| not modelled | 22.4 | 15 | Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases
38 | c1wr7A_ |
| not modelled | 22.2 | 20 | PDB header:ligase Chain: A: PDB Molecule:nedd4-2; PDBTitle: solution structure of the third ww domain of nedd4-2
39 | c2fq1A_ |
| not modelled | 21.6 | 9 | PDB header:hydrolase Chain: A: PDB Molecule:isochorismatase; PDBTitle: crystal structure of the two-domain non-ribosomal peptide synthetase2 entb containing isochorismate lyase and aryl-carrier protein domains
40 | d1sgma2 |
| not modelled | 21.4 | 25 | Fold:Tetracyclin repressor-like, C-terminal domain Superfamily:Tetracyclin repressor-like, C-terminal domain Family:Tetracyclin repressor-like, C-terminal domain
41 | c2djyA_ |
| not modelled | 21.4 | 21 | PDB header:ligase/signaling protein Chain: A: PDB Molecule:smad ubiquitination regulatory factor 2; PDBTitle: solution structure of smurf2 ww3 domain-smad7 py peptide2 complex
42 | c3ot2A_ |
| not modelled | 21.2 | 10 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a putative nuclease belonging to duf8202 (ava_3926) from anabaena variabilis atcc 29413 at 1.96 a resolution
43 | c3ot2B_ |
| not modelled | 21.2 | 10 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a putative nuclease belonging to duf8202 (ava_3926) from anabaena variabilis atcc 29413 at 1.96 a resolution
44 | d1t57a_ |
| not modelled | 20.9 | 16 | Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:MTH1675-like
45 | c1wr4A_ |
| not modelled | 20.7 | 29 | PDB header:ligase Chain: A: PDB Molecule:ubiquitin-protein ligase nedd4-2; PDBTitle: solution structure of the second ww domain of nedd4-2
46 | d1bdga1 |
| not modelled | 20.5 | 16 | Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Hexokinase
47 | c2lawA_ |
| not modelled | 20.4 | 21 | PDB header:signaling protein/transcription Chain: A: PDB Molecule:yorkie homolog; PDBTitle: structure of the second ww domain from human yap in complex with a2 human smad1 derived peptide
48 | c3oqpA_ |
| not modelled | 20.3 | 24 | PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution
49 | c1wmvA_ |
| not modelled | 20.3 | 29 | PDB header:oxidoreductase, apoptosis Chain: A: PDB Molecule:ww domain containing oxidoreductase; PDBTitle: solution structure of the second ww domain of wwox
50 | c2uygF_ |
| not modelled | 20.0 | 20 | PDB header:lyase Chain: F: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystallogaphic structure of the typeii 3-dehydroquinase2 from thermus thermophilus
51 | d1k9ra_ |
| not modelled | 19.8 | 18 | Fold:WW domain-like Superfamily:WW domain Family:WW domain
52 | c2h0rD_ |
| not modelled | 19.5 | 14 | PDB header:hydrolase Chain: D: PDB Molecule:nicotinamidase; PDBTitle: structure of the yeast nicotinamidase pnc1p
53 | d2cfua2 |
| not modelled | 19.5 | 14 | Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Alkylsulfatase-like
54 | d3bzra1 |
| not modelled | 19.4 | 13 | Fold:EscU C-terminal domain-like Superfamily:EscU C-terminal domain-like Family:EscU C-terminal domain-like
55 | c3bzrA_ |
| not modelled | 19.4 | 13 | PDB header:membrane protein, protein transport Chain: A: PDB Molecule:escu; PDBTitle: crystal structure of escu c-terminal domain with n262d mutation, space2 group p 41 21 2
56 | c3t7yB_ |
| not modelled | 19.0 | 16 | PDB header:protein transport Chain: B: PDB Molecule:yop proteins translocation protein u; PDBTitle: structure of an autocleavage-inactive mutant of the cytoplasmic domain2 of ct091, the yscu homologue of chlamydia trachomatis
57 | d3ci0k2 |
| not modelled | 18.6 | 15 | Fold:SAM domain-like Superfamily:GspK insert domain-like Family:GspK insert domain-like
58 | d1tk7a1 |
| not modelled | 18.3 | 14 | Fold:WW domain-like Superfamily:WW domain Family:WW domain
59 | c1ymzA_ |
| not modelled | 18.1 | 36 | PDB header:unknown function Chain: A: PDB Molecule:cc45; PDBTitle: cc45, an artificial ww domain designed using statistical2 coupling analysis
60 | d1j2ra_ |
| not modelled | 17.0 | 14 | Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases
61 | c2k29A_ |
| not modelled | 16.5 | 33 | PDB header:transcription Chain: A: PDB Molecule:antitoxin relb; PDBTitle: structure of the dbd domain of e. coli antitoxin relb
62 | d1i5hw_ |
| not modelled | 16.5 | 20 | Fold:WW domain-like Superfamily:WW domain Family:WW domain
63 | d1f61a_ |
| not modelled | 16.0 | 17 | Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like
64 | d3djba1 |
| not modelled | 15.6 | 14 | Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain
65 | c3lqyA_ |
| not modelled | 15.3 | 18 | PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase hydrolase; PDBTitle: crystal structure of putative isochorismatase hydrolase from2 oleispira antarctica
66 | c2kxqA_ |
| not modelled | 14.2 | 20 | PDB header:protein binding Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf2; PDBTitle: solution structure of smurf2 ww2 and ww3 bound to smad7 py motif2 containing peptide
67 | d1mnta_ |
| not modelled | 14.0 | 19 | Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:Arc/Mnt-like phage repressors
68 | d1a4sa_ |
| not modelled | 13.9 | 18 | Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like
69 | c2jlhA_ |
| not modelled | 13.7 | 16 | PDB header:protein transport Chain: A: PDB Molecule:yop proteins translocation protein u; PDBTitle: crystal structure of the cytoplasmic domain of yersinia2 pestis yscu n263a mutant
70 | c3o93A_ |
| not modelled | 13.0 | 14 | PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: high resolution crystal structures of streptococcus pneumoniae2 nicotinamidase with trapped intermediates provide insights into3 catalytic mechanism and inhibition by aldehydes
71 | c3hu5B_ |
| not modelled | 13.0 | 15 | PDB header:hydrolase Chain: B: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein from desulfovibrio2 vulgaris subsp. vulgaris str. hildenborough
72 | c3oqpB_ |
| not modelled | 12.9 | 24 | PDB header:hydrolase Chain: B: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution
73 | c3ivlA_ |
| not modelled | 12.8 | 12 | PDB header:hydrolase Chain: A: PDB Molecule:putative zinc protease; PDBTitle: the crystal structure of the inactive peptidase domain of a putative2 zinc protease from bordetella parapertussis to 2.2a
74 | c2hg2A_ |
| not modelled | 12.7 | 18 | PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase a; PDBTitle: structure of lactaldehyde dehydrogenase
75 | c3fpvC_ |
| not modelled | 12.6 | 21 | PDB header:heme binding protein Chain: C: PDB Molecule:extracellular haem-binding protein; PDBTitle: crystal structure of hbps
76 | d1lvaa3 |
| not modelled | 12.5 | 11 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:C-terminal fragment of elongation factor SelB
77 | d1zk8a2 |
| not modelled | 12.5 | 21 | Fold:Tetracyclin repressor-like, C-terminal domain Superfamily:Tetracyclin repressor-like, C-terminal domain Family:Tetracyclin repressor-like, C-terminal domain
78 | c3le4A_ |
| not modelled | 12.1 | 22 | PDB header:nuclear protein Chain: A: PDB Molecule:microprocessor complex subunit dgcr8; PDBTitle: crystal structure of the dgcr8 dimerization domain
79 | c2dmvA_ |
| not modelled | 11.9 | 27 | PDB header:ligase Chain: A: PDB Molecule:itchy homolog e3 ubiquitin protein ligase; PDBTitle: solution structure of the second ww domain of itchy homolog2 e3 ubiquitin protein ligase (itch)
80 | c2h6rG_ |
| not modelled | 11.8 | 18 | PDB header:isomerase Chain: G: PDB Molecule:triosephosphate isomerase; PDBTitle: crystal structure of triosephosphate isomerase (tim) from2 methanocaldococcus jannaschii
81 | c2dclB_ |
| not modelled | 11.8 | 14 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical upf0166 protein ph1503; PDBTitle: structure of ph1503 protein from pyrococcus horikoshii ot3
82 | c3ju8B_ |
| not modelled | 11.6 | 33 | PDB header:oxidoreductase Chain: B: PDB Molecule:succinylglutamic semialdehyde dehydrogenase; PDBTitle: crystal structure of succinylglutamic semialdehyde dehydrogenase from2 pseudomonas aeruginosa.
83 | c2a67C_ |
| not modelled | 11.4 | 14 | PDB header:structural genomics, unknown function Chain: C: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein
84 | c2cfuA_ |
| not modelled | 11.4 | 14 | PDB header:hydrolase Chain: A: PDB Molecule:sdsa1; PDBTitle: crystal structure of sdsa1, an alkylsulfatase from2 pseudomonas aeruginosa, in complex with 1-decane-sulfonic-3 acid.
85 | c3k2wD_ |
| not modelled | 11.3 | 20 | PDB header:oxidoreductase Chain: D: PDB Molecule:betaine-aldehyde dehydrogenase; PDBTitle: crystal structure of betaine-aldehyde dehydrogenase from2 pseudoalteromonas atlantica t6c
86 | d2jmfa1 |
| not modelled | 11.3 | 21 | Fold:WW domain-like Superfamily:WW domain Family:WW domain
87 | d1o51a_ |
| not modelled | 10.6 | 14 | Fold:Ferredoxin-like Superfamily:GlnB-like Family:DUF190/COG1993
88 | c2xetB_ |
| not modelled | 10.5 | 5 | PDB header:transport protein Chain: B: PDB Molecule:f1 capsule-anchoring protein; PDBTitle: conserved hydrophobic clusters on the surface of the caf1a usher2 c-terminal domain are important for f1 antigen assembly
89 | c3e0kA_ |
| not modelled | 10.5 | 8 | PDB header:transferase Chain: A: PDB Molecule:amino-acid acetyltransferase; PDBTitle: crystal structure of c-termianl domain of n-acetylglutamate synthase2 from vibrio parahaemolyticus
90 | d2bfda1 |
| not modelled | 10.5 | 11 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Branched-chain alpha-keto acid dehydrogenase PP module
91 | c2vovA_ |
| not modelled | 10.4 | 38 | PDB header:metal-binding protein Chain: A: PDB Molecule:surface-associated protein; PDBTitle: an oxidized tryptophan facilitates copper-binding in2 methylococcus capsulatus secreted protein mope. the3 stucture of wild-type mope to 1.35aa
92 | c3jz4C_ |
| not modelled | 10.3 | 26 | PDB header:oxidoreductase Chain: C: PDB Molecule:succinate-semialdehyde dehydrogenase [nadp+]; PDBTitle: crystal structure of e. coli nadp dependent enzyme
93 | c3iwkB_ |
| not modelled | 10.3 | 25 | PDB header:oxidoreductase Chain: B: PDB Molecule:aminoaldehyde dehydrogenase; PDBTitle: crystal structure of aminoaldehyde dehydrogenase 1 from2 pisum sativum (psamadh1)
94 | d1vp8a_ |
| not modelled | 10.3 | 19 | Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:MTH1675-like
95 | c1qzrA_ |
| not modelled | 10.3 | 10 | PDB header:isomerase Chain: A: PDB Molecule:dna topoisomerase ii; PDBTitle: crystal structure of the atpase region of saccharomyces cerevisiae2 topoisomerase ii bound to icrf-187 (dexrazoxane)
96 | c3hazA_ |
| not modelled | 10.1 | 21 | PDB header:oxidoreductase Chain: A: PDB Molecule:proline dehydrogenase; PDBTitle: crystal structure of bifunctional proline utilization a2 (puta) protein
97 | d1nnsa_ |
| not modelled | 10.0 | 14 | Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase
98 | d2pw9a1 |
| not modelled | 10.0 | 26 | Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:FdhD/NarQ
99 | d1ig8a1 |
| not modelled | 10.0 | 22 | Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Hexokinase

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0