Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP34211
DateThu Jan 5 11:53:05 GMT 2012
Unique Job ID3804b73ac91b026f

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3i1iA_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:homoserine o-acetyltransferase;
PDBTitle: x-ray crystal structure of homoserine o-acetyltransferase from2 bacillus anthracis
Confidence and coverage
Confidence: 99.9% Coverage: 68%
341 residues ( 68% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
407 residues ( 82%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MRVIMKPLRRTLVFFIFSVFLCGTVSARQIEWQSCMTSPYSDWFGKESSSPELLCGYLSV
Secondary structure 

































SS confidence 



























































Disorder  ????














?????????
??






?
?

??????










Disorder confidence 



























































 
   .........70.........80.........90.........100.........110.........120
Sequence  PLKYTDTGKDVSDENIPLVRLAMTKLPAKSKRKGSVIIISGGPGLPGINPYINFDWPVTN
Secondary structure 

































SS confidence 



























































Disorder 






?????????







?
???
?




















?????


Disorder confidence 



























































 
   .........130.........140.........150.........160.........170.........180
Sequence  LRESWDIIGFDPRGVGQSFPAINCQQSNQERLVNVSEKQLILQKINACIHNTGAEVIRHI
Secondary structure 


































SS confidence 



























































Disorder 






























?



























Disorder confidence 



























































 
   .........190.........200.........210.........220.........230.........240
Sequence  GSHEAVYDIERIRQALGDKQLTAVAYSYGTQIAALYAERFPSSIRSIVFDGVVDIDDLND
Secondary structure 


















SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........250.........260.........270.........280.........290.........300
Sequence  NFSWKLRQAHSYQETFDRFAAWCARTKSCPLSSDRNQAIHQFHQLLLKLHNSPLTDSRGE
Secondary structure 


















SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........310.........320.........330.........340.........350.........360
Sequence  SISSDDLISLTTELLLWRSSWPTLATAVRQFSQGIVSNEIETALNSSIASEKVSDALGVI
Secondary structure 






















SS confidence 



























































Disorder 












?



?





















???????????







Disorder confidence 



























































 
   .........370.........380.........390.........400.........410.........420
Sequence  LCVDQSDEQLSQEQRKSRKKALADAFPAVNFEREQSDLPEFCELWPIHRDLQQTRLKNTV
Secondary structure 






























SS confidence 



























































Disorder 







?






















????












?


???????
Disorder confidence 



























































 
   .........430.........440.........450.........460.........470.........480
Sequence  LPSGLLFVAHKYDPTTPWINARKMADKFSAPLLTINGDGHTLALAGTNLCVDEAVVRHLL
Secondary structure 

























SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........490.........
Sequence  FPGKSEDITCQGSGTGDTN
Secondary structure 
















SS confidence 


















Disorder 



???
?
?
???????
Disorder confidence 


















 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3i1i chain A

3D model

Region: 57 - 481
Aligned: 341
Modelled: 341
Confidence: 99.9%
Identity: 12%
PDB header:transferase
Chain: A: PDB Molecule:homoserine o-acetyltransferase;
PDBTitle: x-ray crystal structure of homoserine o-acetyltransferase from2 bacillus anthracis

Phyre2

PDB 1cr6 chain A

3D model

Region: 79 - 479
Aligned: 294
Modelled: 309
Confidence: 99.9%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:epoxide hydrolase;
PDBTitle: crystal structure of murine soluble epoxide hydrolase2 complexed with cpu inhibitor

Phyre2

PDB 2vav chain L

3D model

Region: 79 - 481
Aligned: 298
Modelled: 299
Confidence: 99.9%
Identity: 12%
PDB header:transferase
Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c
PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak)

Phyre2

PDB 2vat chain A domain 1

3D model

Region: 79 - 481
Aligned: 313
Modelled: 314
Confidence: 99.9%
Identity: 13%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: O-acetyltransferase

Phyre2

PDB 2pl5 chain A domain 1

3D model

Region: 79 - 482
Aligned: 315
Modelled: 327
Confidence: 99.9%
Identity: 17%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: O-acetyltransferase

Phyre2

PDB 2b61 chain A domain 1

3D model

Region: 67 - 479
Aligned: 323
Modelled: 332
Confidence: 99.9%
Identity: 12%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: O-acetyltransferase

Phyre2

PDB 2e3j chain A

3D model

Region: 74 - 479
Aligned: 332
Modelled: 347
Confidence: 99.8%
Identity: 13%
PDB header:hydrolase
Chain: A: PDB Molecule:epoxide hydrolase ephb;
PDBTitle: the crystal structure of epoxide hydrolase b (rv1938) from2 mycobacterium tuberculosis at 2.1 angstrom

Phyre2

PDB 1k8q chain A

3D model

Region: 65 - 481
Aligned: 332
Modelled: 348
Confidence: 99.8%
Identity: 11%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Gastric lipase

Phyre2

PDB 1hlg chain A

3D model

Region: 72 - 484
Aligned: 337
Modelled: 344
Confidence: 99.8%
Identity: 13%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Gastric lipase

Phyre2

PDB 1wm1 chain A

3D model

Region: 45 - 478
Aligned: 308
Modelled: 315
Confidence: 99.8%
Identity: 20%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Proline iminopeptidase-like

Phyre2

PDB 1azw chain A

3D model

Region: 80 - 478
Aligned: 289
Modelled: 298
Confidence: 99.8%
Identity: 17%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Proline iminopeptidase-like

Phyre2

PDB 3oos chain A

3D model

Region: 51 - 479
Aligned: 277
Modelled: 287
Confidence: 99.8%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:alpha/beta hydrolase family protein;
PDBTitle: the structure of an alpha/beta fold family hydrolase from bacillus2 anthracis str. sterne

Phyre2

PDB 2y6v chain B

3D model

Region: 56 - 479
Aligned: 293
Modelled: 302
Confidence: 99.8%
Identity: 12%
PDB header:hydrolase
Chain: B: PDB Molecule:peroxisomal membrane protein lpx1;
PDBTitle: peroxisomal alpha-beta-hydrolase lpx1 (yor084w) from2 saccharomyces cerevisiae (crystal form i)

Phyre2

PDB 2qmq chain A

3D model

Region: 80 - 479
Aligned: 261
Modelled: 262
Confidence: 99.8%
Identity: 14%
PDB header:signaling protein
Chain: A: PDB Molecule:protein ndrg2;
PDBTitle: crystal structure of a n-myc downstream regulated 2 protein (ndrg2,2 syld, ndr2, ai182517, au040374) from mus musculus at 1.70 a3 resolution

Phyre2

PDB 3v48 chain B

3D model

Region: 83 - 479
Aligned: 252
Modelled: 263
Confidence: 99.8%
Identity: 12%
PDB header:hydrolase
Chain: B: PDB Molecule:putative aminoacrylate hydrolase rutd;
PDBTitle: crystal structure of the putative alpha/beta hydrolase rutd from2 e.coli

Phyre2

PDB 1cr6 chain A domain 2

3D model

Region: 44 - 479
Aligned: 314
Modelled: 333
Confidence: 99.7%
Identity: 13%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Epoxide hydrolase

Phyre2

PDB 2r11 chain D

3D model

Region: 55 - 479
Aligned: 257
Modelled: 265
Confidence: 99.7%
Identity: 18%
PDB header:hydrolase
Chain: D: PDB Molecule:carboxylesterase np;
PDBTitle: crystal structure of putative hydrolase (2632844) from2 bacillus subtilis at 1.96 a resolution

Phyre2

PDB 3qvm chain A

3D model

Region: 90 - 479
Aligned: 250
Modelled: 256
Confidence: 99.7%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:olei00960;
PDBTitle: the structure of olei00960, a hydrolase from oleispira antarctica

Phyre2

PDB 2xua chain H

3D model

Region: 64 - 481
Aligned: 259
Modelled: 283
Confidence: 99.7%
Identity: 14%
PDB header:hydrolase
Chain: H: PDB Molecule:3-oxoadipate enol-lactonase;
PDBTitle: crystal structure of the enol-lactonase from burkholderia2 xenovorans lb400

Phyre2

PDB 3om8 chain A

3D model

Region: 65 - 479
Aligned: 254
Modelled: 279
Confidence: 99.7%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:probable hydrolase;
PDBTitle: the crystal structure of a hydrolase from pseudomonas aeruginosa pa01

Phyre2
1

c3i1iA_
2

c1cr6A_
3

c2vavL_
4

d2vata1
5

d2pl5a1
6

d2b61a1
7

c2e3jA_
8

d1k8qa_
9

d1hlga_
10

d1wm1a_
11

d1azwa_
12

c3oosA_
13

c2y6vB_
14

c2qmqA_
15

c3v48B_
16

d1cr6a2
17

c2r11D_
18

c3qvmA_
19

c2xuaH_
20

c3om8A_
21



22



23



24



25



26



27



28



29



30



31



32



33



34



35



36



37



38



39



40



41



42



43



44



45



46



47



48



49



50



51



52



53



54



55



56



57



58



59



60



61



62



63



64



65



66



67



68



69



70



71



72



73



74



75



76



77



78



79



80



81



82



83



84



85



86



87



88



89



90



91



92



93



94



95



96



97



98



99



100



101



102



103



104



105



106



107



108



109



110



111



112



113



114



115



116



117



118



119



120



121



122



123



124



125



126



127



128



129



130



131



132



133



134



135



136



137



138



139



140



141



142



143



144



145



146



147



148



149



150



151



152



153



154



155



156



157



158



159



160



161



162



163



164



165



166



167



168



169



170



171



172



173



174



175



176



177



178



179



180



181



182



183



184



185



186



187



188



189



190



191



192



193



194



195



196



197



198



199



200



201



202



203



204



205



206



207



208



209



210



211



212



213



214



215



216



217



218



219



220



221



222



223



224



225



226



227



228



229



230



231



232



233



234



235



236



237



238



239



240



241



242



243



244



245



246



247



248



249



250



251



252



253



254



255



256



257



258



259



260



261






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3i1iA_



99.9 12 PDB header:transferase
Chain: A: PDB Molecule:homoserine o-acetyltransferase;
PDBTitle: x-ray crystal structure of homoserine o-acetyltransferase from2 bacillus anthracis
2c1cr6A_



99.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:epoxide hydrolase;
PDBTitle: crystal structure of murine soluble epoxide hydrolase2 complexed with cpu inhibitor
3c2vavL_



99.9 12 PDB header:transferase
Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c
PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak)
4d2vata1



99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:O-acetyltransferase
5d2pl5a1



99.9 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:O-acetyltransferase
6d2b61a1



99.9 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:O-acetyltransferase
7c2e3jA_



99.8 13 PDB header:hydrolase
Chain: A: PDB Molecule:epoxide hydrolase ephb;
PDBTitle: the crystal structure of epoxide hydrolase b (rv1938) from2 mycobacterium tuberculosis at 2.1 angstrom
8d1k8qa_



99.8 11 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Gastric lipase
9d1hlga_



99.8 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Gastric lipase
10d1wm1a_



99.8 20 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Proline iminopeptidase-like
11d1azwa_



99.8 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Proline iminopeptidase-like
12c3oosA_



99.8 15 PDB header:hydrolase
Chain: A: PDB Molecule:alpha/beta hydrolase family protein;
PDBTitle: the structure of an alpha/beta fold family hydrolase from bacillus2 anthracis str. sterne
13c2y6vB_



99.8 12 PDB header:hydrolase
Chain: B: PDB Molecule:peroxisomal membrane protein lpx1;
PDBTitle: peroxisomal alpha-beta-hydrolase lpx1 (yor084w) from2 saccharomyces cerevisiae (crystal form i)
14c2qmqA_



99.8 14 PDB header:signaling protein
Chain: A: PDB Molecule:protein ndrg2;
PDBTitle: crystal structure of a n-myc downstream regulated 2 protein (ndrg2,2 syld, ndr2, ai182517, au040374) from mus musculus at 1.70 a3 resolution
15c3v48B_



99.8 12 PDB header:hydrolase
Chain: B: PDB Molecule:putative aminoacrylate hydrolase rutd;
PDBTitle: crystal structure of the putative alpha/beta hydrolase rutd from2 e.coli
16d1cr6a2



99.7 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Epoxide hydrolase
17c2r11D_



99.7 18 PDB header:hydrolase
Chain: D: PDB Molecule:carboxylesterase np;
PDBTitle: crystal structure of putative hydrolase (2632844) from2 bacillus subtilis at 1.96 a resolution
18c3qvmA_



99.7 15 PDB header:hydrolase
Chain: A: PDB Molecule:olei00960;
PDBTitle: the structure of olei00960, a hydrolase from oleispira antarctica
19c2xuaH_



99.7 14 PDB header:hydrolase
Chain: H: PDB Molecule:3-oxoadipate enol-lactonase;
PDBTitle: crystal structure of the enol-lactonase from burkholderia2 xenovorans lb400
20c3om8A_



99.7 18 PDB header:hydrolase
Chain: A: PDB Molecule:probable hydrolase;
PDBTitle: the crystal structure of a hydrolase from pseudomonas aeruginosa pa01
21d1zd3a2



not modelled 99.7 18 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Epoxide hydrolase
22d1ivya_



not modelled 99.7 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Serine carboxypeptidase-like
23c2yysA_



not modelled 99.7 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:proline iminopeptidase-related protein;
PDBTitle: crystal structure of the proline iminopeptidase-related protein2 ttha1809 from thermus thermophilus hb8
24d1c4xa_



not modelled 99.6 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carbon-carbon bond hydrolase
25c2cjpA_



not modelled 99.6 16 PDB header:hydrolase
Chain: A: PDB Molecule:epoxide hydrolase;
PDBTitle: structure of potato (solanum tuberosum) epoxide hydrolase i2 (steh1)
26c3flaB_



not modelled 99.6 13 PDB header:hydrolase
Chain: B: PDB Molecule:rifr;
PDBTitle: rifr - type ii thioesterase from rifamycin nrps/pks biosynthetic2 pathway - form 1
27d1b6ga_



not modelled 99.6 15 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloalkane dehalogenase
28d1mtza_



not modelled 99.6 21 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Proline iminopeptidase-like
29c3bwxA_



not modelled 99.6 19 PDB header:hydrolase
Chain: A: PDB Molecule:alpha/beta hydrolase;
PDBTitle: crystal structure of an alpha/beta hydrolase (yp_496220.1) from2 novosphingobium aromaticivorans dsm 12444 at 1.50 a resolution
30c1u2eA_



not modelled 99.6 13 PDB header:hydrolase
Chain: A: PDB Molecule:2-hydroxy-6-ketonona-2,4-dienedioic acid
PDBTitle: crystal structure of the c-c bond hydrolase mhpc
31d1uk8a_



not modelled 99.6 18 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carbon-carbon bond hydrolase
32c3nwoA_



not modelled 99.6 17 PDB header:hydrolase
Chain: A: PDB Molecule:proline iminopeptidase;
PDBTitle: crystal structure of proline iminopeptidase mycobacterium smegmatis
33d1q0ra_



not modelled 99.6 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Aclacinomycin methylesterase RdmC
34c3fsgC_



not modelled 99.6 18 PDB header:hydrolase
Chain: C: PDB Molecule:alpha/beta superfamily hydrolase;
PDBTitle: crystal structure of alpha/beta superfamily hydrolase from oenococcus2 oeni psu-1
35c2wj4B_



not modelled 99.6 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:1h-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase;
PDBTitle: crystal structure of the cofactor-devoid 1-h-3-hydroxy-4-2 oxoquinaldine 2,4-dioxygenase (hod) from arthrobacter3 nitroguajacolicus ru61a anaerobically complexed with its4 natural substrate 1-h-3-hydroxy-4-oxoquinaldine
36c2vf2A_



not modelled 99.6 19 PDB header:hydrolase
Chain: A: PDB Molecule:2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate
PDBTitle: x-ray crystal structure of hsad from mycobacterium2 tuberculosis
37c3a2nF_



not modelled 99.6 16 PDB header:hydrolase
Chain: F: PDB Molecule:haloalkane dehalogenase;
PDBTitle: crystal structure of dbja (wild type type ii p21)
38d1ehya_



not modelled 99.6 16 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Epoxide hydrolase
39d1wpxa1



not modelled 99.6 19 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Serine carboxypeptidase-like
40c2xt0A_



not modelled 99.5 11 PDB header:hydrolase
Chain: A: PDB Molecule:haloalkane dehalogenase;
PDBTitle: dehalogenase dppa from plesiocystis pacifica sir-i
41d1qo7a_



not modelled 99.5 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Epoxide hydrolase
42c3e0xB_



not modelled 99.5 18 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:lipase-esterase related protein;
PDBTitle: the crystal structure of a lipase-esterase related protein2 from clostridium acetobutylicum atcc 824
43d1m33a_



not modelled 99.5 19 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Biotin biosynthesis protein BioH
44c3ibtA_



not modelled 99.5 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:1h-3-hydroxy-4-oxoquinoline 2,4-dioxygenase;
PDBTitle: structure of 1h-3-hydroxy-4-oxoquinoline 2,4-dioxygenase (qdo)
45c1y37A_



not modelled 99.5 11 PDB header:hydrolase
Chain: A: PDB Molecule:fluoroacetate dehalogenase;
PDBTitle: structure of fluoroacetate dehalogenase from burkholderia sp. fa1
46d2rhwa1



not modelled 99.5 18 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carbon-carbon bond hydrolase
47c3u1tA_



not modelled 99.5 15 PDB header:hydrolase
Chain: A: PDB Molecule:dmma haloalkane dehalogenase;
PDBTitle: haloalkane dehalogenase, dmma, of marine microbial origin
48c3e3aA_



not modelled 99.5 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:possible peroxidase bpoc;
PDBTitle: the structure of rv0554 from mycobacterium tuberculosis
49c3bf7B_



not modelled 99.5 18 PDB header:hydrolase
Chain: B: PDB Molecule:esterase ybff;
PDBTitle: 1.1 resolution structure of ybff, a new esterase from2 escherichia coli: a unique substrate-binding crevice3 generated by domain arrangement
50c3kdaB_



not modelled 99.5 18 PDB header:hydrolase
Chain: B: PDB Molecule:cftr inhibitory factor (cif);
PDBTitle: crystal structure of the cftr inhibitory factor cif with the h269a2 mutation
51c2hu7A_



not modelled 99.5 17 PDB header:hydrolase
Chain: A: PDB Molecule:acylamino-acid-releasing enzyme;
PDBTitle: binding of inhibitors by acylaminoacyl peptidase
52c3jw8A_



not modelled 99.5 16 PDB header:hydrolase
Chain: A: PDB Molecule:mgll protein;
PDBTitle: crystal structure of human mono-glyceride lipase
53c3h04A_



not modelled 99.5 11 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: the crystal structure of the protein with unknown function from2 staphylococcus aureus subsp. aureus mu50
54d1imja_



not modelled 99.5 19 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Ccg1/TafII250-interacting factor B (Cib)
55c3fobA_



not modelled 99.5 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:bromoperoxidase;
PDBTitle: crystal structure of bromoperoxidase from bacillus anthracis
56d1ex9a_



not modelled 99.5 16 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Bacterial lipase
57c2xmzA_



not modelled 99.5 17 PDB header:lyase
Chain: A: PDB Molecule:hydrolase, alpha/beta hydrolase fold family;
PDBTitle: structure of menh from s. aureus
58d1ac5a_



not modelled 99.5 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Serine carboxypeptidase-like
59c1wprA_



not modelled 99.5 16 PDB header:signaling protein
Chain: A: PDB Molecule:sigma factor sigb regulation protein rsbq;
PDBTitle: crystal structure of rsbq inhibited by pmsf
60d1a8sa_



not modelled 99.5 15 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
61d1a8qa_



not modelled 99.5 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
62c1zoiC_



not modelled 99.5 19 PDB header:hydrolase
Chain: C: PDB Molecule:esterase;
PDBTitle: crystal structure of a stereoselective esterase from2 pseudomonas putida ifo12996
63c3kxpD_



not modelled 99.5 16 PDB header:hydrolase
Chain: D: PDB Molecule:alpha-(n-acetylaminomethylene)succinic acid
PDBTitle: crystal structure of e-2-(acetamidomethylene)succinate2 hydrolase
64c3llcA_



not modelled 99.4 15 PDB header:hydrolase
Chain: A: PDB Molecule:putative hydrolase;
PDBTitle: crystal structure of putative hydrolase (yp_002548124.1) from2 agrobacterium vitis s4 at 1.80 a resolution
65d1xkta_



not modelled 99.4 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Thioesterase domain of polypeptide, polyketide and fatty acid synthases
66d1bn7a_



not modelled 99.4 15 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloalkane dehalogenase
67c3qitB_



not modelled 99.4 19 PDB header:hydrolase
Chain: B: PDB Molecule:polyketide synthase;
PDBTitle: thioesterase domain from curacin biosynthetic pathway
68d1hkha_



not modelled 99.4 20 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
69c3r0vA_



not modelled 99.4 17 PDB header:hydrolase
Chain: A: PDB Molecule:alpha/beta hydrolase fold protein;
PDBTitle: the crystal structure of an alpha/beta hydrolase from sphaerobacter2 thermophilus dsm 20745.
70c3p2mA_



not modelled 99.4 15 PDB header:hydrolase
Chain: A: PDB Molecule:possible hydrolase;
PDBTitle: crystal structure of a novel esterase rv0045c from mycobacterium2 tuberculosis
71c3l80A_



not modelled 99.4 17 PDB header:hydrolase
Chain: A: PDB Molecule:putative uncharacterized protein smu.1393c;
PDBTitle: crystal structure of smu.1393c from streptococcus mutans ua159
72d1e89a_



not modelled 99.4 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Hydroxynitrile lyase-like
73c3r3xA_



not modelled 99.4 15 PDB header:hydrolase
Chain: A: PDB Molecule:fluoroacetate dehalogenase;
PDBTitle: crystal structure of the fluoroacetate dehalogenase rpa1163 -2 asp110asn/bromoacetate
74c3bdiA_



not modelled 99.4 20 PDB header:hydrolase
Chain: A: PDB Molecule:uncharacterized protein ta0194;
PDBTitle: crystal structure of predicted cib-like hydrolase (np_393672.1) from2 thermoplasma acidophilum at 1.45 a resolution
75c3qyjB_



not modelled 99.4 11 PDB header:hydrolase
Chain: B: PDB Molecule:alr0039 protein;
PDBTitle: crystal structure of alr0039, a putative alpha/beta hydrolase from2 nostoc sp pcc 7120.
76c3hjuB_



not modelled 99.4 18 PDB header:hydrolase
Chain: B: PDB Molecule:monoglyceride lipase;
PDBTitle: crystal structure of human monoglyceride lipase
77c2ockA_



not modelled 99.4 19 PDB header:hydrolase
Chain: A: PDB Molecule:valacyclovir hydrolase;
PDBTitle: crystal structure of valacyclovir hydrolase d123n mutant
78d3c70a1



not modelled 99.4 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Hydroxynitrile lyase-like
79c3qmwD_



not modelled 99.4 12 PDB header:hydrolase
Chain: D: PDB Molecule:thioesterase;
PDBTitle: redj with peg molecule bound in the active site
80c3dqzB_



not modelled 99.4 15 PDB header:lyase
Chain: B: PDB Molecule:alpha-hydroxynitrile lyase-like protein;
PDBTitle: structure of the hydroxynitrile lyase from arabidopsis2 thaliana
81d1mj5a_



not modelled 99.4 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloalkane dehalogenase
82d1brta_



not modelled 99.4 19 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
83c2ronA_



not modelled 99.4 16 PDB header:hydrolase
Chain: A: PDB Molecule:surfactin synthetase thioesterase subunit;
PDBTitle: the external thioesterase of the surfactin-synthetase
84c3dyvA_



not modelled 99.4 14 PDB header:hydrolase
Chain: A: PDB Molecule:esterase d;
PDBTitle: snapshots of esterase d from lactobacillus rhamnosus:2 insights into a rotation driven catalytic mechanism
85c3gzjB_



not modelled 99.3 13 PDB header:hydrolase
Chain: B: PDB Molecule:polyneuridine-aldehyde esterase;
PDBTitle: crystal structure of polyneuridine aldehyde esterase2 complexed with 16-epi-vellosimine
86c1qgeD_



not modelled 99.3 18 PDB header:hydrolase
Chain: D: PDB Molecule:protein (triacylglycerol hydrolase);
PDBTitle: new crystal form of pseudomonas glumae (formerly chromobacterium2 viscosum atcc 6918) lipase
87d1j1ia_



not modelled 99.3 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carbon-carbon bond hydrolase
88c1j1iA_



not modelled 99.3 17 PDB header:hydrolase
Chain: A: PDB Molecule:meta cleavage compound hydrolase;
PDBTitle: crystal structure of a his-tagged serine hydrolase involved2 in the carbazole degradation (carc enzyme)
89c2pseA_



not modelled 99.3 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:renilla-luciferin 2-monooxygenase;
PDBTitle: crystal structures of the luciferase and green fluorescent2 protein from renilla reniformis
90d1va4a_



not modelled 99.3 21 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
91d1xkla_



not modelled 99.3 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Hydroxynitrile lyase-like
92d1a88a_



not modelled 99.3 18 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
93c3mveB_



not modelled 99.3 20 PDB header:lyase
Chain: B: PDB Molecule:upf0255 protein vv1_0328;
PDBTitle: crystal structure of a novel pyruvate decarboxylase
94c3fnbB_



not modelled 99.3 17 PDB header:hydrolase
Chain: B: PDB Molecule:acylaminoacyl peptidase smu_737;
PDBTitle: crystal structure of acylaminoacyl peptidase smu_737 from2 streptococcus mutans ua159
95c2qjwA_



not modelled 99.3 30 PDB header:hydrolase
Chain: A: PDB Molecule:uncharacterized protein xcc1541;
PDBTitle: crystal structure of a putative hydrolase of the alpha/beta2 superfamily (xcc1541) from xanthomonas campestris pv. campestris at3 1.35 a resolution
96c2wtmC_



not modelled 99.3 17 PDB header:hydrolase
Chain: C: PDB Molecule:est1e;
PDBTitle: est1e from butyrivibrio proteoclasticus
97c3lcrA_



not modelled 99.3 15 PDB header:hydrolase
Chain: A: PDB Molecule:tautomycetin biosynthetic pks;
PDBTitle: thioesterase from tautomycetin biosynthhetic pathway
98c3jyhD_



not modelled 99.3 16 PDB header:hydrolase
Chain: D: PDB Molecule:dipeptidyl-peptidase 2;
PDBTitle: human dipeptidyl peptidase dpp7
99c2qvbA_



not modelled 99.2 14 PDB header:hydrolase
Chain: A: PDB Molecule:haloalkane dehalogenase 3;
PDBTitle: crystal structure of haloalkane dehalogenase rv2579 from mycobacterium2 tuberculosis
100c2eepA_



not modelled 99.2 17 PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl aminopeptidase iv, putative;
PDBTitle: prolyl tripeptidyl aminopeptidase complexed with an inhibitor
101d2fuka1



not modelled 99.2 21 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Atu1826-like
102c3qm1A_



not modelled 99.1 15 PDB header:hydrolase
Chain: A: PDB Molecule:cinnamoyl esterase;
PDBTitle: crystal structure of the lactobacillus johnsonii cinnamoyl esterase2 lj0536 s106a mutant in complex with ethylferulate, form ii
103c2hdwB_



not modelled 99.1 7 PDB header:hydrolase
Chain: B: PDB Molecule:hypothetical protein pa2218;
PDBTitle: crystal structure of hypothetical protein pa2218 from pseudomonas2 aeruginosa
104d1uxoa_



not modelled 99.1 21 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:YdeN-like
105c2qruA_



not modelled 99.1 10 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of an alpha/beta hydrolase superfamily protein from2 enterococcus faecalis
106c2jbwB_



not modelled 99.1 22 PDB header:hydrolase
Chain: B: PDB Molecule:2,6-dihydroxy-pseudo-oxynicotine hydrolase;
PDBTitle: crystal structure of the 2,6-dihydroxy-pseudo-oxynicotine2 hydrolase.
107d1ispa_



not modelled 99.1 20 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Bacterial lipase
108d4lipd_



not modelled 99.1 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Bacterial lipase
109c2rauA_



not modelled 99.1 16 PDB header:hydrolase
Chain: A: PDB Molecule:putative esterase;
PDBTitle: crystal structure of a putative lipase (np_343859.1) from sulfolobus2 solfataricus at 1.85 a resolution
110d2h7xa1



not modelled 99.1 23 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Thioesterase domain of polypeptide, polyketide and fatty acid synthases
111c2h7xA_



not modelled 99.1 20 PDB header:hydrolase
Chain: A: PDB Molecule:type i polyketide synthase pikaiv;
PDBTitle: pikromycin thioesterase adduct with reduced triketide2 affinity label
112c3fcyB_



not modelled 99.1 14 PDB header:hydrolase
Chain: B: PDB Molecule:xylan esterase 1;
PDBTitle: crystal structure of acetyl xylan esterase 1 from2 thermoanaerobacterium sp. jw/sl ys485
113c2q0xA_



not modelled 99.1 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: alpha/beta hydrolase fold protein of unknown function
114c2g5tA_



not modelled 99.1 22 PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl peptidase 4;
PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag
115c2qs9A_



not modelled 99.1 23 PDB header:structural protein
Chain: A: PDB Molecule:retinoblastoma-binding protein 9;
PDBTitle: crystal structure of the human retinoblastoma-binding2 protein 9 (rbbp-9). nesg target hr2978
116c3azqA_



not modelled 99.1 16 PDB header:hydrolase
Chain: A: PDB Molecule:aminopeptidase;
PDBTitle: crystal structure of puromycin hydrolase s511a mutant complexed with2 pgg
117c3h2iA_



not modelled 99.1 17 PDB header:hydrolase
Chain: A: PDB Molecule:esterase;
PDBTitle: crystal structure of n228w mutant of the rice cell wall2 degrading esterase lipa from xanthomonas oryzae
118d1l7aa_



not modelled 99.1 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Acetyl xylan esterase-like
119d2r8ba1



not modelled 99.0 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carboxylesterase/thioesterase 1
120d1tqha_



not modelled 99.0 19 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carboxylesterase/lipase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0