Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	P	D	V	S	Q	A	L	A	W	L	E	K	H	P	Q	A	L	K	G	I	Q	R	G	L	E	R	E	T	L	R	V	N	A	D	G	T	L	A	T	T	G	H	P	E	A	L	G	S	A	L	T	H	K	W	I	T	T	D
Secondary structure
SS confidence
Disorder		?	?	?	?																?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		F	A	E	A	L	L	E	F	I	T	P	V	D	G	D	I	E	H	M	L	T	F	M	R	D	L	H	R	Y	T	A	R	N	M	G	D	E	R	M	W	P	L	S	M	P	C	Y	I	A	E	G	Q	D	I	E	L	A	Q	Y	G
Secondary structure
SS confidence
Disorder																																																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	S	N	T	G	R	F	K	T	L	Y	R	E	G	L	K	N	R	Y	G	A	L	M	Q	T	I	S	G	V	H	Y	N	F	S	L	P	M	A	F	W	Q	A	K	C	G	D	I	S	G	A	D	A	K	E	K	I	S	A	G	Y
Secondary structure
SS confidence
Disorder					?																																												?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		F	R	V	I	R	N	Y	Y	R	F	G	W	V	I	P	Y	L	F	G	A	S	P	A	I	C	S	S	F	L	Q	G	K	P	T	S	L	P	F	E	K	T	E	C	G	M	Y	Y	L	P	Y	A	T	S	L	R	L	S	D	L	G
Secondary structure
SS confidence
Disorder																															?		?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		Y	T	N	K	S	Q	S	N	L	G	I	T	F	N	D	L	Y	E	Y	V	A	G	L	K	Q	A	I	K	T	P	S	E	E	Y	A	K	I	G	I	E	K	D	G	K	R	L	Q	I	N	S	N	V	L	Q	I	E	N	E	L	Y
Secondary structure
SS confidence
Disorder		?	?																																								?				?			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		A	P	I	R	P	K	R	V	T	R	S	G	E	S	P	S	D	A	L	L	R	G	G	I	E	Y	I	E	V	R	S	L	D	I	N	P	F	S	P	I	G	V	D	E	Q	Q	V	R	F	L	D	L	F	M	V	W	C	A	L	A
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		D	A	P	E	M	S	S	S	E	L	A	C	T	R	V	N	W	N	R	V	I	L	E	G	R	K	P	G	L	T	L	G	I	G	C	E	T	A	Q	F	P	L	P	Q	V	G	K	D	L	F	R	D	L	K	R	V	A	Q	T	L
Secondary structure
SS confidence
Disorder						?																		?															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		D	S	I	N	G	G	E	A	Y	Q	K	V	C	D	E	L	V	A	C	F	D	N	P	D	L	T	F	S	A	R	I	L	R	S	M	I	D	T	G	I	G	G	T	G	K	A	F	A	E	A	Y	R	N	L	L	R	E	E	P	L
Secondary structure
SS confidence
Disorder					?																																																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.
Sequence		E	I	L	R	E	E	D	F	V	A	E	R	E	A	S	E	R	R	Q	Q	E	M	E	A	A	D	T	E	P	F	A	V	W	L	E	K	H	A
Secondary structure
SS confidence
Disorder				?	?																				?	?	?	?										?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2d32 chain A domain 1 Region: 1 - 518 Aligned: 510 Modelled: 518 Confidence: 100.0% Identity: 99% Fold: Glutamine synthetase/guanido kinase Superfamily: Glutamine synthetase/guanido kinase Family: Glutamate-cysteine ligase Phyre2 PDB 3nzt chain A Region: 19 - 517 Aligned: 484 Modelled: 494 Confidence: 100.0% Identity: 35% PDB header:ligase Chain: A: PDB Molecule:glutamate--cysteine ligase; PDBTitle: 2.0 angstrom crystal structure of glutamate--cysteine ligase (gsha)2 ftom francisella tularensis in complex with amp Phyre2 PDB 3ln6 chain A Region: 19 - 510 Aligned: 427 Modelled: 444 Confidence: 100.0% Identity: 32% PDB header:ligase Chain: A: PDB Molecule:glutathione biosynthesis bifunctional protein gshab; PDBTitle: crystal structure of a bifunctional glutathione synthetase from2 streptococcus agalactiae Phyre2 PDB 3ln7 chain A Region: 10 - 510 Aligned: 436 Modelled: 447 Confidence: 100.0% Identity: 27% PDB header:ligase Chain: A: PDB Molecule:glutathione biosynthesis bifunctional protein gshab; PDBTitle: crystal structure of a bifunctional glutathione synthetase from2 pasteurella multocida Phyre2 PDB 1r8g chain A Region: 22 - 471 Aligned: 336 Modelled: 340 Confidence: 100.0% Identity: 19% Fold: Glutamine synthetase/guanido kinase Superfamily: Glutamine synthetase/guanido kinase Family: Glutamate-cysteine ligase family 2 (GCS2) Phyre2 PDB 1tt4 chain A Region: 21 - 469 Aligned: 339 Modelled: 353 Confidence: 100.0% Identity: 19% Fold: Glutamine synthetase/guanido kinase Superfamily: Glutamine synthetase/guanido kinase Family: Glutamate-cysteine ligase family 2 (GCS2) Phyre2 PDB 1tt4 chain B Region: 21 - 469 Aligned: 339 Modelled: 353 Confidence: 100.0% Identity: 19% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative cytoplasmic protein; PDBTitle: structure of np459575, a predicted glutathione synthase from2 salmonella typhimurium Phyre2 PDB 2gwc chain E Region: 5 - 458 Aligned: 380 Modelled: 410 Confidence: 99.8% Identity: 16% PDB header:ligase Chain: E: PDB Molecule:glutamate cysteine ligase; PDBTitle: crystal structure of plant glutamate cysteine ligase in complex with a2 transition state analogue Phyre2 PDB 3lvw chain A Region: 191 - 334 Aligned: 119 Modelled: 144 Confidence: 81.1% Identity: 15% PDB header:ligase Chain: A: PDB Molecule:glutamate--cysteine ligase; PDBTitle: glutathione-inhibited scgcl Phyre2 PDB 2bvc chain A domain 2 Region: 147 - 244 Aligned: 75 Modelled: 98 Confidence: 62.1% Identity: 15% Fold: Glutamine synthetase/guanido kinase Superfamily: Glutamine synthetase/guanido kinase Family: Glutamine synthetase catalytic domain Phyre2 PDB 3lgg chain A Region: 316 - 354 Aligned: 39 Modelled: 39 Confidence: 58.3% Identity: 10% PDB header:hydrolase Chain: A: PDB Molecule:adenosine deaminase cecr1; PDBTitle: crystal structure of human adenosine deaminase growth factor,2 adenosine deaminase type 2 (ada2) complexed with transition state3 analogue, coformycin Phyre2 PDB 1f52 chain A domain 2 Region: 147 - 244 Aligned: 74 Modelled: 95 Confidence: 57.7% Identity: 18% Fold: Glutamine synthetase/guanido kinase Superfamily: Glutamine synthetase/guanido kinase Family: Glutamine synthetase catalytic domain Phyre2 PDB 1jv1 chain A Region: 316 - 341 Aligned: 25 Modelled: 26 Confidence: 53.0% Identity: 24% Fold: Nucleotide-diphospho-sugar transferases Superfamily: Nucleotide-diphospho-sugar transferases Family: UDP-glucose pyrophosphorylase Phyre2 PDB 2yqs chain A Region: 316 - 341 Aligned: 25 Modelled: 26 Confidence: 50.2% Identity: 28% PDB header:transferase Chain: A: PDB Molecule:udp-n-acetylglucosamine pyrophosphorylase; PDBTitle: crystal structure of uridine-diphospho-n-acetylglucosamine2 pyrophosphorylase from candida albicans, in the product-binding form Phyre2 PDB 1hto chain B Region: 147 - 244 Aligned: 75 Modelled: 98 Confidence: 49.5% Identity: 15% PDB header:ligase Chain: B: PDB Molecule:glutamine synthetase; PDBTitle: crystallographic structure of a relaxed glutamine synthetase from2 mycobacterium tuberculosis Phyre2 PDB 2ixo chain A domain 1 Region: 178 - 201 Aligned: 24 Modelled: 24 Confidence: 49.3% Identity: 21% Fold: PTPA-like Superfamily: PTPA-like Family: PTPA-like Phyre2 PDB 3oc9 chain A Region: 316 - 341 Aligned: 25 Modelled: 26 Confidence: 47.1% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:udp-n-acetylglucosamine pyrophosphorylase; PDBTitle: crystal structure of putative udp-n-acetylglucosamine2 pyrophosphorylase from entamoeba histolytica Phyre2 PDB 1gsu chain A domain 2 Region: 299 - 336 Aligned: 32 Modelled: 38 Confidence: 43.5% Identity: 22% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Glutathione S-transferase (GST), N-terminal domain Phyre2 PDB 1vm8 chain A Region: 316 - 341 Aligned: 25 Modelled: 26 Confidence: 43.3% Identity: 24% Fold: Nucleotide-diphospho-sugar transferases Superfamily: Nucleotide-diphospho-sugar transferases Family: UDP-glucose pyrophosphorylase Phyre2 PDB 2g62 chain A Region: 178 - 210 Aligned: 33 Modelled: 33 Confidence: 42.0% Identity: 24% PDB header:hydrolase activator Chain: A: PDB Molecule:protein phosphatase 2a, regulatory subunit b' (pr 53); PDBTitle: crystal structure of human ptpa Phyre2 1 d2d32a1 2 c3nztA_ 3 c3ln6A_ 4 c3ln7A_ 5 d1r8ga_ 6 d1tt4a_ 7 c1tt4B_ 8 c2gwcE_ 9 c3lvwA_ 10 d2bvca2 11 c3lggA_ 12 d1f52a2 13 d1jv1a_ 14 c2yqsA_ 15 c1htoB_ 16 d2ixoa1 17 c3oc9A_ 18 d1gsua2 19 d1vm8a_ 20 c2g62A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2d32a1 100.0 99 Fold:Glutamine synthetase/guanido kinase Superfamily:Glutamine synthetase/guanido kinase Family:Glutamate-cysteine ligase 2 c3nztA_ 100.0 35 PDB header:ligase Chain: A: PDB Molecule:glutamate--cysteine ligase; PDBTitle: 2.0 angstrom crystal structure of glutamate--cysteine ligase (gsha)2 ftom francisella tularensis in complex with amp 3 c3ln6A_ 100.0 32 PDB header:ligase Chain: A: PDB Molecule:glutathione biosynthesis bifunctional protein gshab; PDBTitle: crystal structure of a bifunctional glutathione synthetase from2 streptococcus agalactiae 4 c3ln7A_ 100.0 27 PDB header:ligase Chain: A: PDB Molecule:glutathione biosynthesis bifunctional protein gshab; PDBTitle: crystal structure of a bifunctional glutathione synthetase from2 pasteurella multocida 5 d1r8ga_ 100.0 19 Fold:Glutamine synthetase/guanido kinase Superfamily:Glutamine synthetase/guanido kinase Family:Glutamate-cysteine ligase family 2 (GCS2) 6 d1tt4a_ 100.0 19 Fold:Glutamine synthetase/guanido kinase Superfamily:Glutamine synthetase/guanido kinase Family:Glutamate-cysteine ligase family 2 (GCS2) 7 c1tt4B_ 100.0 19 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative cytoplasmic protein; PDBTitle: structure of np459575, a predicted glutathione synthase from2 salmonella typhimurium 8 c2gwcE_ 99.8 16 PDB header:ligase Chain: E: PDB Molecule:glutamate cysteine ligase; PDBTitle: crystal structure of plant glutamate cysteine ligase in complex with a2 transition state analogue 9 c3lvwA_ 81.1 15 PDB header:ligase Chain: A: PDB Molecule:glutamate--cysteine ligase; PDBTitle: glutathione-inhibited scgcl 10 d2bvca2 62.1 15 Fold:Glutamine synthetase/guanido kinase Superfamily:Glutamine synthetase/guanido kinase Family:Glutamine synthetase catalytic domain 11 c3lggA_ 58.3 10 PDB header:hydrolase Chain: A: PDB Molecule:adenosine deaminase cecr1; PDBTitle: crystal structure of human adenosine deaminase growth factor,2 adenosine deaminase type 2 (ada2) complexed with transition state3 analogue, coformycin 12 d1f52a2 57.7 18 Fold:Glutamine synthetase/guanido kinase Superfamily:Glutamine synthetase/guanido kinase Family:Glutamine synthetase catalytic domain 13 d1jv1a_ 53.0 24 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:UDP-glucose pyrophosphorylase 14 c2yqsA_ 50.2 28 PDB header:transferase Chain: A: PDB Molecule:udp-n-acetylglucosamine pyrophosphorylase; PDBTitle: crystal structure of uridine-diphospho-n-acetylglucosamine2 pyrophosphorylase from candida albicans, in the product-binding form 15 c1htoB_ 49.5 15 PDB header:ligase Chain: B: PDB Molecule:glutamine synthetase; PDBTitle: crystallographic structure of a relaxed glutamine synthetase from2 mycobacterium tuberculosis 16 d2ixoa1 49.3 21 Fold:PTPA-like Superfamily:PTPA-like Family:PTPA-like 17 c3oc9A_ 47.1 20 PDB header:transferase Chain: A: PDB Molecule:udp-n-acetylglucosamine pyrophosphorylase; PDBTitle: crystal structure of putative udp-n-acetylglucosamine2 pyrophosphorylase from entamoeba histolytica 18 d1gsua2 43.5 22 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 19 d1vm8a_ 43.3 24 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:UDP-glucose pyrophosphorylase 20 c2g62A_ 42.0 24 PDB header:hydrolase activator Chain: A: PDB Molecule:protein phosphatase 2a, regulatory subunit b' (pr 53); PDBTitle: crystal structure of human ptpa 21 d2d6fc3 not modelled 41.0 15 Fold:Glutamine synthetase/guanido kinase Superfamily:Glutamine synthetase/guanido kinase Family:GatB/GatE catalytic domain-like 22 d1tqja_ not modelled 39.6 30 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 23 c3lq7B_ not modelled 39.3 33 PDB header:transferase Chain: B: PDB Molecule:glutathione s-transferase; PDBTitle: crystal structure of glutathione s-transferase from2 agrobacterium tumefaciens str. c58 24 d1rpxa_ not modelled 35.9 26 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 25 d1zq1c3 not modelled 34.5 19 Fold:Glutamine synthetase/guanido kinase Superfamily:Glutamine synthetase/guanido kinase Family:GatB/GatE catalytic domain-like 26 d2f2ab2 not modelled 34.1 15 Fold:Glutamine synthetase/guanido kinase Superfamily:Glutamine synthetase/guanido kinase Family:GatB/GatE catalytic domain-like 27 c1tu8A_ not modelled 32.2 30 PDB header:transferase Chain: A: PDB Molecule:glutathione s-transferase 2; PDBTitle: structure of onchoverca volvulus pi-class glutathione s-2 transferase with its kompetitive inhibitor s-hexyl-gsh 28 d1tu7a2 not modelled 30.1 29 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 29 c3llkA_ not modelled 28.8 14 PDB header:oxidoreductase Chain: A: PDB Molecule:sulfhydryl oxidase 1; PDBTitle: sulfhydryl oxidase fragment of human qsox1 30 d2ixma1 not modelled 28.6 24 Fold:PTPA-like Superfamily:PTPA-like Family:PTPA-like 31 d1f52a1 not modelled 27.5 17 Fold:beta-Grasp (ubiquitin-like) Superfamily:Glutamine synthetase, N-terminal domain Family:Glutamine synthetase, N-terminal domain 32 c3h0mE_ not modelled 27.2 26 PDB header:ligase Chain: E: PDB Molecule:aspartyl/glutamyl-trna(asn/gln) amidotransferase PDBTitle: structure of trna-dependent amidotransferase gatcab from2 aquifex aeolicus 33 d2bvca1 not modelled 27.0 22 Fold:beta-Grasp (ubiquitin-like) Superfamily:Glutamine synthetase, N-terminal domain Family:Glutamine synthetase, N-terminal domain 34 c2g5iB_ not modelled 26.9 15 PDB header:ligase Chain: B: PDB Molecule:aspartyl/glutamyl-trna(asn/gln) amidotransferase PDBTitle: structure of trna-dependent amidotransferase gatcab2 complexed with adp-alf4 35 c3rysA_ not modelled 26.8 19 PDB header:hydrolase Chain: A: PDB Molecule:adenosine deaminase 1; PDBTitle: the crystal structure of adenine deaminase (aaur1117) from2 arthrobacter aurescens 36 d2cvda2 not modelled 26.5 29 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 37 d2ixna1 not modelled 26.4 30 Fold:PTPA-like Superfamily:PTPA-like Family:PTPA-like 38 d1okta2 not modelled 26.2 32 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 39 c2qm2B_ not modelled 25.6 56 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative hopj type iii effector protein; PDBTitle: putative hopj type iii effector protein from vibrio parahaemolyticus 40 d2fnoa2 not modelled 25.0 30 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 41 c3al0B_ not modelled 23.9 26 PDB header:ligase/rna Chain: B: PDB Molecule:aspartyl/glutamyl-trna(asn/gln) amidotransferase subunit b; PDBTitle: crystal structure of the glutamine transamidosome from thermotoga2 maritima in the glutamylation state. 42 c2fnoB_ not modelled 23.4 30 PDB header:transferase Chain: B: PDB Molecule:agr_pat_752p; PDBTitle: crystal structure of a glutathione s-transferase (atu5508) from2 agrobacterium tumefaciens str. c58 at 2.00 a resolution 43 c1zq1D_ not modelled 23.3 19 PDB header:lyase Chain: D: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit e; PDBTitle: structure of gatde trna-dependent amidotransferase from2 pyrococcus abyssi 44 c2jfkD_ not modelled 23.2 14 PDB header:transferase Chain: D: PDB Molecule:fatty acid synthase; PDBTitle: structure of the mat domain of human fas with malonyl-coa 45 d1k3ya2 not modelled 23.1 36 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 46 c2d6fC_ not modelled 21.8 15 PDB header:ligase/rna Chain: C: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit e; PDBTitle: crystal structure of glu-trna(gln) amidotransferase in the2 complex with trna(gln) 47 d2amxa1 not modelled 21.3 19 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Adenosine/AMP deaminase 48 d1ml6a2 not modelled 21.0 32 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 49 d1oe8a2 not modelled 20.8 36 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 50 c2d3aJ_ not modelled 20.3 44 PDB header:ligase Chain: J: PDB Molecule:glutamine synthetase; PDBTitle: crystal structure of the maize glutamine synthetase2 complexed with adp and methionine sulfoximine phosphate 51 d2a2ra2 not modelled 20.2 29 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 52 d1tqxa_ not modelled 20.0 21 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 53 c3ogzA_ not modelled 19.7 22 PDB header:transferase Chain: A: PDB Molecule:udp-sugar pyrophosphorylase; PDBTitle: protein structure of usp from l. major in apo-form 54 d2icya2 not modelled 19.0 39 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:UDP-glucose pyrophosphorylase 55 d1qwia_ not modelled 18.7 11 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 56 d1o9aa1 not modelled 18.5 35 Fold:FnI-like domain Superfamily:FnI-like domain Family:Fibronectin type I module 57 d1glqa2 not modelled 18.2 32 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 58 c3js3C_ not modelled 17.9 22 PDB header:lyase Chain: C: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystal structure of type i 3-dehydroquinate dehydratase (arod) from2 clostridium difficile with covalent reaction intermediate 59 c1nwdC_ not modelled 17.2 56 PDB header:binding protein/hydrolase Chain: C: PDB Molecule:glutamate decarboxylase; PDBTitle: solution structure of ca2+/calmodulin bound to the c-2 terminal domain of petunia glutamate decarboxylase 60 c1nwdB_ not modelled 17.2 56 PDB header:binding protein/hydrolase Chain: B: PDB Molecule:glutamate decarboxylase; PDBTitle: solution structure of ca2+/calmodulin bound to the c-2 terminal domain of petunia glutamate decarboxylase 61 d2c4ja2 not modelled 17.0 25 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 62 c3o6xC_ not modelled 16.9 13 PDB header:ligase Chain: C: PDB Molecule:glutamine synthetase; PDBTitle: crystal structure of the type iii glutamine synthetase from2 bacteroides fragilis 63 d1xfba1 not modelled 16.6 34 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 64 c1m0uB_ not modelled 16.6 25 PDB header:transferase Chain: B: PDB Molecule:gst2 gene product; PDBTitle: crystal structure of the drosophila glutathione s-2 transferase-2 in complex with glutathione 65 d1w5fa2 not modelled 16.3 14 Fold:Bacillus chorismate mutase-like Superfamily:Tubulin C-terminal domain-like Family:Tubulin, C-terminal domain 66 d1xw6a2 not modelled 15.9 21 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 67 c3inpA_ not modelled 15.9 23 PDB header:isomerase Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase; PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis. 68 c1c72A_ not modelled 15.8 24 PDB header:transferase Chain: A: PDB Molecule:protein (glutathione s-transferase); PDBTitle: tyr115, gln165 and trp209 contribute to the 1,2-epoxy-3-(p-2 nitrophenoxy)propane conjugating activities of glutathione3 s-transferase cgstm1-1 69 d2gsta2 not modelled 15.6 22 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 70 c3gwnA_ not modelled 15.3 9 PDB header:oxidoreductase Chain: A: PDB Molecule:probable fad-linked sulfhydryl oxidase r596; PDBTitle: crystal structure of the fad binding domain from mimivirus sulfhydryl2 oxidase r596 71 c1oktA_ not modelled 15.3 32 PDB header:transferase Chain: A: PDB Molecule:glutathione s-transferase; PDBTitle: x-ray structure of glutathione s-transferase from the2 malarial parasite plasmodium falciparum 72 d1pd212 not modelled 14.8 32 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 73 d1a4ma_ not modelled 14.5 31 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Adenosine/AMP deaminase 74 d2f66c1 not modelled 14.4 19 Fold:Long alpha-hairpin Superfamily:Endosomal sorting complex assembly domain Family:VPS37 C-terminal domain-like 75 c1tw9C_ not modelled 14.2 25 PDB header:transferase Chain: C: PDB Molecule:glutathione s-transferase 2; PDBTitle: glutathione transferase-2, apo form, from the nematode heligmosomoides2 polygyrus 76 c3qa8A_ not modelled 13.9 19 PDB header:immune system, signaling protein Chain: A: PDB Molecule:mgc80376 protein; PDBTitle: crystal structure of inhibitor of kappa b kinase beta 77 d1fdja_ not modelled 13.6 26 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 78 c2qc8J_ not modelled 13.6 56 PDB header:ligase Chain: J: PDB Molecule:glutamine synthetase; PDBTitle: crystal structure of human glutamine synthetase in complex with adp2 and methionine sulfoximine phosphate 79 d2qapa1 not modelled 13.5 35 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 80 d2fhea2 not modelled 13.4 25 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 81 c2qapC_ not modelled 13.4 35 PDB header:lyase Chain: C: PDB Molecule:fructose-1,6-bisphosphate aldolase; PDBTitle: fructose-1,6-bisphosphate aldolase from leishmania mexicana 82 d2gsqa2 not modelled 13.0 29 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 83 d1a5ca_ not modelled 12.9 29 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 84 c3kk4B_ not modelled 12.7 21 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein bp1543; PDBTitle: uncharacterized protein bp1543 from bordetella pertussis tohama i 85 c2ws2B_ not modelled 12.7 25 PDB header:transferase Chain: B: PDB Molecule:glutathione s-transferase; PDBTitle: the 2 angstrom structure of a nu-class gst from haemonchus contortus 86 d3gtub2 not modelled 12.6 25 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 87 c2qnlA_ not modelled 12.5 18 PDB header:signaling protein Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a putative dna damage-inducible protein2 (chu_0679) from cytophaga hutchinsonii atcc 33406 at 1.50 a3 resolution 88 d1zaia1 not modelled 12.1 31 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 89 c3nrhA_ not modelled 11.7 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein bf1032; PDBTitle: crystal structure of protein bf1032 from bacteroides fragilis,2 northeast structural genomics consortium target bfr309 90 c1iyiA_ not modelled 11.5 29 PDB header:isomerase Chain: A: PDB Molecule:hematopoietic prostagladin d synthase; PDBTitle: crystal structure of hematopoietic prostaglandin d synthase 91 c1yq1A_ not modelled 11.5 29 PDB header:transferase Chain: A: PDB Molecule:glutathione s-transferase; PDBTitle: structural genomics of caenorhabditis elegans: glutathione2 s-transferase 92 d1u5tb2 not modelled 11.5 50 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Vacuolar sorting protein domain 93 c3obeB_ not modelled 11.4 7 PDB header:isomerase Chain: B: PDB Molecule:sugar phosphate isomerase/epimerase; PDBTitle: crystal structure of a sugar phosphate isomerase/epimerase (bdi_3400)2 from parabacteroides distasonis atcc 8503 at 1.70 a resolution 94 c2pc4B_ not modelled 11.3 29 PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: crystal structure of fructose-bisphosphate aldolase from plasmodium2 falciparum in complex with trap-tail determined at 2.4 angstrom3 resolution 95 d1a34a_ not modelled 11.2 33 Fold:Nucleoplasmin-like/VP (viral coat and capsid proteins) Superfamily:Satellite viruses Family:Satellite viruses 96 d2cazc1 not modelled 11.0 19 Fold:Long alpha-hairpin Superfamily:Endosomal sorting complex assembly domain Family:VPS37 C-terminal domain-like 97 c2q4jB_ not modelled 11.0 39 PDB header:transferase Chain: B: PDB Molecule:probable utp-glucose-1-phosphate uridylyltransferase 2; PDBTitle: ensemble refinement of the protein crystal structure of gene product2 from arabidopsis thaliana at3g03250, a putative udp-glucose3 pyrophosphorylase 98 d1duga2 not modelled 10.8 18 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 99 c1gshA_ not modelled 10.7 35 PDB header:glutathione biosynthesis ligase Chain: A: PDB Molecule:glutathione biosynthetic ligase; PDBTitle: structure of escherichia coli glutathione synthetase at ph 7.5

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0