Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	S	S	L	R	I	V	A	I	T	N	C	P	A	G	I	A	H	T	Y	M	V	A	E	A	L	E	Q	K	A	R	S	L	G	H	T	I	K	V	E	T	Q	G	S	S	G	V	E	N	R	L	S	S	E	E	I	A	A	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?																																									?		?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	Y	V	I	L	A	T	G	R	G	L	S	G	D	D	R	A	R	F	A	G	K	K	V	Y	E	I	A	I	S	Q	A	L	K	N	I	D	Q	I	F	S	E	L	P	T	N	S	Q	L	F	A	A	D	S	G	V	K	L	G	K
Secondary structure
SS confidence
Disorder																																														?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Q	E	V	Q	S	G	S	V	M	S	H	L	M	A	G	V	S	A	A	L	P	F	V	I	G	G	G	I	L	V	A	L	A	N	M	L	V	Q	F	G	L	P	Y	T	D	M	S	K	G	A	P	S	F	T	W	V	V	E	S	I
Secondary structure
SS confidence
Disorder		?		?	?																																					?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	Y	L	G	F	T	F	M	I	P	I	M	G	A	Y	I	A	S	S	I	A	D	K	P	A	F	A	P	A	F	L	V	C	Y	L	A	N	D	K	A	L	L	G	T	Q	S	G	A	G	F	L	G	A	V	V	L	G	L	A	I
Secondary structure
SS confidence
Disorder																							?															?		?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	Y	F	V	F	W	F	R	K	V	R	L	G	K	A	L	Q	P	L	L	G	S	M	L	I	P	F	V	T	L	L	V	F	G	V	L	T	Y	Y	V	I	G	P	V	M	S	D	L	M	G	G	L	L	H	F	L	N	T	I	P
Secondary structure
SS confidence
Disorder															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		P	S	M	K	F	A	A	A	F	L	V	G	A	M	L	A	F	D	M	G	G	P	I	N	K	T	A	W	F	F	C	F	S	L	L	E	K	H	I	Y	D	W	Y	A	I	V	G	V	V	A	L	M	P	P	V	A	A	G	L	A
Secondary structure
SS confidence
Disorder																																																		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		T	F	I	A	P	K	L	F	T	R	Q	E	K	E	A	A	S	S	A	I	V	V	G	A	T	V	A	T	E	P	A	I	P	Y	A	L	A	A	P	L	P	M	I	T	A	N	T	L	A	G	G	I	T	G	V	L	V	I	A	F
Secondary structure
SS confidence
Disorder																?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		G	I	K	R	L	A	P	G	L	G	I	F	D	P	L	I	G	L	M	S	P	V	G	S	F	Y	L	V	L	A	I	G	L	A	L	N	I	S	F	I	I	V	L	K	G	L	W	L	R	R	K	A	K	A	A	Q	Q	E	L	V
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?		?	?							?	?																											?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.
Sequence		H	E	H
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2r48 chain A domain 1 Region: 6 - 111 Aligned: 103 Modelled: 106 Confidence: 100.0% Identity: 41% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: PTS system IIB component-like Family: PTS system, Fructose specific IIB subunit-like Phyre2 PDB 2kyr chain A Region: 4 - 106 Aligned: 101 Modelled: 103 Confidence: 100.0% Identity: 40% PDB header:transferase Chain: A: PDB Molecule:fructose-like phosphotransferase enzyme iib component 1; PDBTitle: solution structure of enzyme iib subunit of pts system from2 escherichia coli k12. northeast structural genomics consortium target3 er315/ontario center for structural proteomics target ec0544 Phyre2 PDB 3qnq chain D Region: 121 - 483 Aligned: 360 Modelled: 363 Confidence: 100.0% Identity: 14% PDB header:membrane protein, transport protein Chain: D: PDB Molecule:pts system, cellobiose-specific iic component; PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system Phyre2 PDB 2r4q chain A domain 1 Region: 6 - 111 Aligned: 101 Modelled: 106 Confidence: 100.0% Identity: 35% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: PTS system IIB component-like Family: PTS system, Fructose specific IIB subunit-like Phyre2 PDB 1tvm chain A Region: 2 - 105 Aligned: 93 Modelled: 104 Confidence: 97.0% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:pts system, galactitol-specific iib component; PDBTitle: nmr structure of enzyme gatb of the galactitol-specific2 phosphoenolpyruvate-dependent phosphotransferase system Phyre2 PDB 1ydg chain A Region: 3 - 67 Aligned: 63 Modelled: 65 Confidence: 96.7% Identity: 11% Fold: Flavodoxin-like Superfamily: Flavoproteins Family: WrbA-like Phyre2 PDB 2a5l chain A domain 1 Region: 6 - 67 Aligned: 60 Modelled: 62 Confidence: 96.5% Identity: 15% Fold: Flavodoxin-like Superfamily: Flavoproteins Family: WrbA-like Phyre2 PDB 3nbm chain A Region: 4 - 106 Aligned: 95 Modelled: 103 Confidence: 96.0% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:pts system, lactose-specific iibc components; PDBTitle: the lactose-specific iib component domain structure of the2 phosphoenolpyruvate:carbohydrate phosphotransferase system (pts) from3 streptococcus pneumoniae. Phyre2 PDB 1iib chain A Region: 13 - 105 Aligned: 87 Modelled: 93 Confidence: 95.9% Identity: 16% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: PTS system IIB component-like Family: PTS system, Lactose/Cellobiose specific IIB subunit Phyre2 PDB 3czc chain A Region: 9 - 105 Aligned: 86 Modelled: 84 Confidence: 95.7% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:rmpb; PDBTitle: the crystal structure of a putative pts iib(ptxb) from2 streptococcus mutans Phyre2 PDB 2l2q chain A Region: 2 - 105 Aligned: 93 Modelled: 104 Confidence: 95.7% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:pts system, cellobiose-specific iib component (cela); PDBTitle: solution structure of cellobiose-specific phosphotransferase iib2 component protein from borrelia burgdorferi Phyre2 PDB 1vkr chain A Region: 3 - 108 Aligned: 95 Modelled: 106 Confidence: 95.7% Identity: 18% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: PTS system IIB component-like Family: PTS system, Lactose/Cellobiose specific IIB subunit Phyre2 PDB 1vkr chain A Region: 3 - 108 Aligned: 95 Modelled: 106 Confidence: 95.7% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:mannitol-specific pts system enzyme iiabc components; PDBTitle: structure of iib domain of the mannitol-specific permease enzyme ii Phyre2 PDB 3fni chain A Region: 2 - 137 Aligned: 133 Modelled: 136 Confidence: 95.1% Identity: 11% PDB header:oxidoreductase Chain: A: PDB Molecule:putative diflavin flavoprotein a 3; PDBTitle: crystal structure of a diflavin flavoprotein a3 (all3895) from nostoc2 sp., northeast structural genomics consortium target nsr431a Phyre2 PDB 2ark chain A domain 1 Region: 6 - 67 Aligned: 54 Modelled: 62 Confidence: 94.8% Identity: 24% Fold: Flavodoxin-like Superfamily: Flavoproteins Family: WrbA-like Phyre2 PDB 1ycg chain A domain 1 Region: 3 - 67 Aligned: 61 Modelled: 65 Confidence: 93.6% Identity: 21% Fold: Flavodoxin-like Superfamily: Flavoproteins Family: Flavodoxin-related Phyre2 PDB 1vme chain A domain 1 Region: 4 - 67 Aligned: 62 Modelled: 64 Confidence: 91.4% Identity: 13% Fold: Flavodoxin-like Superfamily: Flavoproteins Family: Flavodoxin-related Phyre2 PDB 3p0r chain A Region: 6 - 67 Aligned: 62 Modelled: 62 Confidence: 90.7% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:azoreductase; PDBTitle: crystal structure of azoreductase from bacillus anthracis str. sterne Phyre2 PDB 3b6i chain B Region: 6 - 67 Aligned: 60 Modelled: 62 Confidence: 88.2% Identity: 20% PDB header:flavoprotein Chain: B: PDB Molecule:flavoprotein wrba; PDBTitle: wrba from escherichia coli, native structure Phyre2 PDB 3lcm chain B Region: 5 - 67 Aligned: 62 Modelled: 63 Confidence: 88.1% Identity: 13% PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of smu.1420 from streptococcus mutans ua159 Phyre2 1 d2r48a1 2 c2kyrA_ 3 c3qnqD_ 4 d2r4qa1 5 c1tvmA_ 6 d1ydga_ 7 d2a5la1 8 c3nbmA_ 9 d1iiba_ 10 c3czcA_ 11 c2l2qA_ 12 d1vkra_ 13 c1vkrA_ 14 c3fniA_ 15 d2arka1 16 d1ycga1 17 d1vmea1 18 c3p0rA_ 19 c3b6iB_ 20 c3lcmB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2r48a1 100.0 41 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:PTS system IIB component-like Family:PTS system, Fructose specific IIB subunit-like 2 c2kyrA_ 100.0 40 PDB header:transferase Chain: A: PDB Molecule:fructose-like phosphotransferase enzyme iib component 1; PDBTitle: solution structure of enzyme iib subunit of pts system from2 escherichia coli k12. northeast structural genomics consortium target3 er315/ontario center for structural proteomics target ec0544 3 c3qnqD_ 100.0 14 PDB header:membrane protein, transport protein Chain: D: PDB Molecule:pts system, cellobiose-specific iic component; PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system 4 d2r4qa1 100.0 35 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:PTS system IIB component-like Family:PTS system, Fructose specific IIB subunit-like 5 c1tvmA_ 97.0 13 PDB header:transferase Chain: A: PDB Molecule:pts system, galactitol-specific iib component; PDBTitle: nmr structure of enzyme gatb of the galactitol-specific2 phosphoenolpyruvate-dependent phosphotransferase system 6 d1ydga_ 96.7 11 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:WrbA-like 7 d2a5la1 96.5 15 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:WrbA-like 8 c3nbmA_ 96.0 12 PDB header:transferase Chain: A: PDB Molecule:pts system, lactose-specific iibc components; PDBTitle: the lactose-specific iib component domain structure of the2 phosphoenolpyruvate:carbohydrate phosphotransferase system (pts) from3 streptococcus pneumoniae. 9 d1iiba_ 95.9 16 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:PTS system IIB component-like Family:PTS system, Lactose/Cellobiose specific IIB subunit 10 c3czcA_ 95.7 19 PDB header:transferase Chain: A: PDB Molecule:rmpb; PDBTitle: the crystal structure of a putative pts iib(ptxb) from2 streptococcus mutans 11 c2l2qA_ 95.7 18 PDB header:transferase Chain: A: PDB Molecule:pts system, cellobiose-specific iib component (cela); PDBTitle: solution structure of cellobiose-specific phosphotransferase iib2 component protein from borrelia burgdorferi 12 d1vkra_ 95.7 18 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:PTS system IIB component-like Family:PTS system, Lactose/Cellobiose specific IIB subunit 13 c1vkrA_ 95.7 18 PDB header:transferase Chain: A: PDB Molecule:mannitol-specific pts system enzyme iiabc components; PDBTitle: structure of iib domain of the mannitol-specific permease enzyme ii 14 c3fniA_ 95.1 11 PDB header:oxidoreductase Chain: A: PDB Molecule:putative diflavin flavoprotein a 3; PDBTitle: crystal structure of a diflavin flavoprotein a3 (all3895) from nostoc2 sp., northeast structural genomics consortium target nsr431a 15 d2arka1 94.8 24 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:WrbA-like 16 d1ycga1 93.6 21 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 17 d1vmea1 91.4 13 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 18 c3p0rA_ 90.7 16 PDB header:oxidoreductase Chain: A: PDB Molecule:azoreductase; PDBTitle: crystal structure of azoreductase from bacillus anthracis str. sterne 19 c3b6iB_ 88.2 20 PDB header:flavoprotein Chain: B: PDB Molecule:flavoprotein wrba; PDBTitle: wrba from escherichia coli, native structure 20 c3lcmB_ 88.1 13 PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of smu.1420 from streptococcus mutans ua159 21 c3d7nA_ not modelled 87.5 29 PDB header:electron transport Chain: A: PDB Molecule:flavodoxin, wrba-like protein; PDBTitle: the crystal structure of the flavodoxin, wrba-like protein from2 agrobacterium tumefaciens 22 d1e5da1 not modelled 86.1 22 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 23 c2zkiH_ not modelled 85.9 13 PDB header:transcription Chain: H: PDB Molecule:199aa long hypothetical trp repressor binding PDBTitle: crystal structure of hypothetical trp repressor binding2 protein from sul folobus tokodaii (st0872) 24 c3fmfA_ not modelled 85.3 31 PDB header:ligase Chain: A: PDB Molecule:dethiobiotin synthetase; PDBTitle: crystal structure of mycobacterium tuberculosis dethiobiotin2 synthetase complexed with 7,8 diaminopelargonic acid carbamate 25 c2q62A_ not modelled 85.1 13 PDB header:flavoprotein Chain: A: PDB Molecule:arsh; PDBTitle: crystal structure of arsh from sinorhizobium meliloti 26 c1zggA_ not modelled 84.5 23 PDB header:hydrolase Chain: A: PDB Molecule:putative low molecular weight protein-tyrosine- PDBTitle: solution structure of a low molecular weight protein2 tyrosine phosphatase from bacillus subtilis 27 c3f2vA_ not modelled 84.1 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:general stress protein 14; PDBTitle: crystal structure of the general stress protein 142 (tde0354) in complex with fmn from treponema denticola,3 northeast structural genomics consortium target tdr58. 28 c2v9cA_ not modelled 82.3 24 PDB header:oxidoreductase Chain: A: PDB Molecule:fmn-dependent nadh-azoreductase 1; PDBTitle: x-ray crystallographic structure of a pseudomonas2 aeruginosa azoreductase in complex with methyl red. 29 c1ychD_ not modelled 80.8 13 PDB header:oxidoreductase Chain: D: PDB Molecule:nitric oxide reductase; PDBTitle: x-ray crystal structures of moorella thermoacetica fpra.2 novel diiron site structure and mechanistic insights into3 a scavenging nitric oxide reductase 30 d1sqsa_ not modelled 80.2 18 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Hypothetical protein SP1951 31 d2qwxa1 not modelled 80.0 20 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Quinone reductase 32 d1t0ba_ not modelled 79.5 19 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:ThuA-like 33 c2ohiB_ not modelled 79.0 19 PDB header:oxidoreductase Chain: B: PDB Molecule:type a flavoprotein fpra; PDBTitle: crystal structure of coenzyme f420h2 oxidase (fpra), a diiron2 flavoprotein, reduced state 34 c2kncA_ not modelled 78.5 14 PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex 35 d1rtta_ not modelled 77.9 18 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:NADPH-dependent FMN reductase 36 c3snoA_ not modelled 77.6 28 PDB header:transferase Chain: A: PDB Molecule:hypothetical aminotransferase; PDBTitle: crystal structure of a hypothetical aminotransferase (ncgl2491) from2 corynebacterium glutamicum atcc 13032 kitasato at 1.60 a resolution 37 c2cwdA_ not modelled 77.2 24 PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight phosphotyrosine protein phosphatase; PDBTitle: crystal structure of tt1001 protein from thermus thermophilus hb8 38 d1qrda_ not modelled 75.5 25 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Quinone reductase 39 c2gi4A_ not modelled 75.0 23 PDB header:hydrolase Chain: A: PDB Molecule:possible phosphotyrosine protein phosphatase; PDBTitle: solution structure of the low molecular weight protein2 tyrosine phosphatase from campylobacter jejuni. 40 c3klbA_ not modelled 74.6 16 PDB header:flavoprotein Chain: A: PDB Molecule:putative flavoprotein; PDBTitle: crystal structure of putative flavoprotein in complex with fmn2 (yp_213683.1) from bacteroides fragilis nctc 9343 at 1.75 a3 resolution 41 c3jviA_ not modelled 74.0 11 PDB header:hydrolase Chain: A: PDB Molecule:protein tyrosine phosphatase; PDBTitle: product state mimic crystal structure of protein tyrosine phosphatase2 from entamoeba histolytica 42 c1vmeB_ not modelled 73.6 11 PDB header:electron transport Chain: B: PDB Molecule:flavoprotein; PDBTitle: crystal structure of flavoprotein (tm0755) from thermotoga maritima at2 1.80 a resolution 43 c3rh0A_ not modelled 71.7 13 PDB header:oxidoreductase Chain: A: PDB Molecule:arsenate reductase; PDBTitle: corynebacterium glutamicum mycothiol/mycoredoxin1-dependent arsenate2 reductase cg_arsc2 44 c3k9cA_ not modelled 71.5 14 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, laci family protein; PDBTitle: crystal structure of laci transcriptional regulator from rhodococcus2 species. 45 c2hpvA_ not modelled 70.8 21 PDB header:oxidoreductase Chain: A: PDB Molecule:fmn-dependent nadh-azoreductase; PDBTitle: crystal structure of fmn-dependent azoreductase from enterococcus2 faecalis 46 c3rpeA_ not modelled 70.1 22 PDB header:oxidoreductase Chain: A: PDB Molecule:modulator of drug activity b; PDBTitle: 1.1 angstrom crystal structure of putative modulator of drug activity2 (mdab) from yersinia pestis co92. 47 d1dxqa_ not modelled 67.4 23 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Quinone reductase 48 d2z98a1 not modelled 66.7 11 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Quinone reductase 49 d2fzva1 not modelled 66.2 8 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:NADPH-dependent FMN reductase 50 d1acoa2 not modelled 64.9 17 Fold:Aconitase iron-sulfur domain Superfamily:Aconitase iron-sulfur domain Family:Aconitase iron-sulfur domain 51 d1duvg1 not modelled 64.4 15 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 52 c2fzvC_ not modelled 61.2 7 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:putative arsenical resistance protein; PDBTitle: crystal structure of an apo form of a flavin-binding protein from2 shigella flexneri 53 c3h9gA_ not modelled 60.6 10 PDB header:transferase/antibiotic Chain: A: PDB Molecule:mccb protein; PDBTitle: crystal structure of e. coli mccb + mcca-n7isoasn 54 d1d1qa_ not modelled 60.6 17 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 55 c5acnA_ not modelled 57.8 17 PDB header:lyase(carbon-oxygen) Chain: A: PDB Molecule:aconitase; PDBTitle: structure of activated aconitase. formation of the (4fe-4s)2 cluster in the crystal 56 c3fvwA_ not modelled 57.5 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative nad(p)h-dependent fmn reductase; PDBTitle: crystal structure of the q8dwd8_strmu protein from2 streptococcus mutans. northeast structural genomics3 consortium target smr99. 57 d2fz5a1 not modelled 57.4 15 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 58 d1t5ba_ not modelled 57.3 11 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Quinone reductase 59 c1wrvB_ not modelled 56.8 14 PDB header:transferase Chain: B: PDB Molecule:branched-chain amino acid aminotransferase; PDBTitle: crystal structure of t.th.hb8 branched-chain amino acid2 aminotransferase 60 d1u7ga_ not modelled 56.3 13 Fold:Ammonium transporter Superfamily:Ammonium transporter Family:Ammonium transporter 61 c3hlyA_ not modelled 56.0 14 PDB header:flavoprotein Chain: A: PDB Molecule:flavodoxin-like domain; PDBTitle: crystal structure of the flavodoxin-like domain from2 synechococcus sp q5mzp6_synp6 protein. northeast structural3 genomics consortium target snr135d. 62 d2b3ya2 not modelled 53.3 32 Fold:Aconitase iron-sulfur domain Superfamily:Aconitase iron-sulfur domain Family:Aconitase iron-sulfur domain 63 c2q9uB_ not modelled 53.1 21 PDB header:oxidoreductase Chain: B: PDB Molecule:a-type flavoprotein; PDBTitle: crystal structure of the flavodiiron protein from giardia2 intestinalis 64 d5nula_ not modelled 52.9 21 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 65 d1otha1 not modelled 52.3 21 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 66 d2oara1 not modelled 51.2 13 Fold:Gated mechanosensitive channel Superfamily:Gated mechanosensitive channel Family:Gated mechanosensitive channel 67 d1vkna1 not modelled 51.0 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 68 d1b1ca_ not modelled 50.3 19 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Cytochrome p450 reductase N-terminal domain-like 69 c3cswB_ not modelled 48.8 22 PDB header:transferase Chain: B: PDB Molecule:putative branched-chain-amino-acid aminotransferase; PDBTitle: crystal structure of a putative branched-chain amino acid2 aminotransferase (tm0831) from thermotoga maritima at 2.15 a3 resolution 70 d1iyea_ not modelled 48.6 29 Fold:D-aminoacid aminotransferase-like PLP-dependent enzymes Superfamily:D-aminoacid aminotransferase-like PLP-dependent enzymes Family:D-aminoacid aminotransferase-like PLP-dependent enzymes 71 d1vlva1 not modelled 47.7 18 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 72 d1dxha1 not modelled 47.5 21 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 73 c2oarA_ not modelled 46.8 13 PDB header:membrane protein Chain: A: PDB Molecule:large-conductance mechanosensitive channel; PDBTitle: mechanosensitive channel of large conductance (mscl) 74 c2b2hA_ not modelled 46.7 11 PDB header:transport protein Chain: A: PDB Molecule:ammonium transporter; PDBTitle: ammonium transporter amt-1 from a. fulgidus (as) 75 c2p2gD_ not modelled 45.5 21 PDB header:transferase Chain: D: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase from mycobacterium2 tuberculosis (rv1656): orthorhombic form 76 c3s99A_ not modelled 45.5 19 PDB header:lipid binding protein Chain: A: PDB Molecule:basic membrane lipoprotein; PDBTitle: crystal structure of a basic membrane lipoprotein from brucella2 melitensis, iodide soak 77 c2ef0A_ not modelled 45.3 21 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase from thermus2 thermophilus 78 d1jw9b_ not modelled 44.7 16 Fold:Activating enzymes of the ubiquitin-like proteins Superfamily:Activating enzymes of the ubiquitin-like proteins Family:Molybdenum cofactor biosynthesis protein MoeB 79 c2b3yB_ not modelled 44.3 29 PDB header:lyase Chain: B: PDB Molecule:iron-responsive element binding protein 1; PDBTitle: structure of a monoclinic crystal form of human cytosolic aconitase2 (irp1) 80 d1h05a_ not modelled 44.1 26 Fold:Flavodoxin-like Superfamily:Type II 3-dehydroquinate dehydratase Family:Type II 3-dehydroquinate dehydratase 81 c1zfnA_ not modelled 42.5 13 PDB header:transferase Chain: A: PDB Molecule:adenylyltransferase thif; PDBTitle: structural analysis of escherichia coli thif 82 c3kydB_ not modelled 42.4 14 PDB header:ligase Chain: B: PDB Molecule:sumo-activating enzyme subunit 2; PDBTitle: human sumo e1~sumo1-amp tetrahedral intermediate mimic 83 c3o1hB_ not modelled 42.4 23 PDB header:signaling protein Chain: B: PDB Molecule:periplasmic protein tort; PDBTitle: crystal structure of the tors sensor domain - tort complex in the2 presence of tmao 84 c1y8qD_ not modelled 40.9 11 PDB header:ligase Chain: D: PDB Molecule:ubiquitin-like 2 activating enzyme e1b; PDBTitle: sumo e1 activating enzyme sae1-sae2-mg-atp complex 85 d1dg9a_ not modelled 40.5 17 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 86 c2eq8C_ not modelled 40.0 24 PDB header:oxidoreductase Chain: C: PDB Molecule:pyruvate dehydrogenase complex, dihydrolipoamide PDBTitle: crystal structure of lipoamide dehydrogenase from thermus thermophilus2 hb8 with psbdp 87 d1q6za1 not modelled 39.3 11 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 88 d5pnta_ not modelled 39.0 19 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 89 c2vzhA_ not modelled 39.0 23 PDB header:oxidoreductase Chain: A: PDB Molecule:nadh-dependent fmn reductase; PDBTitle: structures of nadh:fmn oxidoreductase (emob)-fmn complex 90 d2gk3a1 not modelled 37.7 19 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:STM3548-like 91 d1gqoa_ not modelled 37.6 18 Fold:Flavodoxin-like Superfamily:Type II 3-dehydroquinate dehydratase Family:Type II 3-dehydroquinate dehydratase 92 c3djeA_ not modelled 37.4 18 PDB header:oxidoreductase Chain: A: PDB Molecule:fructosyl amine: oxygen oxidoreductase; PDBTitle: crystal structure of the deglycating enzyme fructosamine2 oxidase from aspergillus fumigatus (amadoriase ii) in3 complex with fsa 93 d1ja1a2 not modelled 36.6 17 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Cytochrome p450 reductase N-terminal domain-like 94 d1rlia_ not modelled 36.2 21 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Hypothetical protein YwqN 95 c3orsD_ not modelled 36.0 11 PDB header:isomerase,biosynthetic protein Chain: D: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide mutase; PDBTitle: crystal structure of n5-carboxyaminoimidazole ribonucleotide mutase2 from staphylococcus aureus 96 c3n8kG_ not modelled 36.0 26 PDB header:lyase Chain: G: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: type ii dehydroquinase from mycobacterium tuberculosis complexed with2 citrazinic acid 97 c3d0oA_ not modelled 35.9 21 PDB header:oxidoreductase Chain: A: PDB Molecule:l-lactate dehydrogenase 1; PDBTitle: crystal structure of lactate dehydrogenase from2 staphylococcus aureus 98 c2hqbA_ not modelled 35.4 13 PDB header:transcription Chain: A: PDB Molecule:transcriptional activator of comk gene; PDBTitle: crystal structure of a transcriptional activator of comk2 gene from bacillus halodurans 99 c1vknC_ not modelled 34.9 16 PDB header:oxidoreductase Chain: C: PDB Molecule:n-acetyl-gamma-glutamyl-phosphate reductase; PDBTitle: crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase2 (tm1782) from thermotoga maritima at 1.80 a resolution 100 d5ldha1 not modelled 34.0 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 101 c1ojuA_ not modelled 33.7 13 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: 2.8 a resolution structure of malate dehydrogenase from2 archaeoglobus fulgidus in complex with etheno-nad. 102 c2an1D_ not modelled 33.1 21 PDB header:transferase Chain: D: PDB Molecule:putative kinase; PDBTitle: structural genomics, the crystal structure of a putative kinase from2 salmonella typhimurim lt2 103 c3lwzC_ not modelled 33.0 15 PDB header:lyase Chain: C: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: 1.65 angstrom resolution crystal structure of type ii 3-2 dehydroquinate dehydratase (aroq) from yersinia pestis 104 c2eq9C_ not modelled 32.3 36 PDB header:oxidoreductase Chain: C: PDB Molecule:pyruvate dehydrogenase complex, dihydrolipoamide PDBTitle: crystal structure of lipoamide dehydrogenase from thermus thermophilus2 hb8 with psbdb 105 d1jvna2 not modelled 31.6 20 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 106 c2ad5B_ not modelled 31.5 20 PDB header:ligase Chain: B: PDB Molecule:ctp synthase; PDBTitle: mechanisms of feedback regulation and drug resistance of ctp2 synthetases: structure of the e. coli ctps/ctp complex at 2.8-3 angstrom resolution. 107 d1pvva1 not modelled 31.1 14 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 108 d1s1ma1 not modelled 30.9 19 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 109 c1wziA_ not modelled 30.3 20 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: structural basis for alteration of cofactor specificity of2 malate dehydrogenase from thermus flavus 110 d1qzua_ not modelled 30.0 21 Fold:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD 111 d1d4aa_ not modelled 29.6 20 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Quinone reductase 112 d1jf8a_ not modelled 29.5 8 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 113 c2fqxA_ not modelled 29.5 16 PDB header:transport protein Chain: A: PDB Molecule:membrane lipoprotein tmpc; PDBTitle: pnra from treponema pallidum complexed with guanosine 114 c3f6sI_ not modelled 29.0 20 PDB header:electron transport Chain: I: PDB Molecule:flavodoxin; PDBTitle: desulfovibrio desulfuricans (atcc 29577) oxidized flavodoxin2 alternate conformers 115 d1t0ia_ not modelled 28.5 19 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:NADPH-dependent FMN reductase 116 c1vlvA_ not modelled 28.2 18 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase (tm1097) from2 thermotoga maritima at 2.25 a resolution 117 d1oboa_ not modelled 27.7 17 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 118 d1i0za1 not modelled 27.0 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 119 c1z0zC_ not modelled 26.6 18 PDB header:transferase Chain: C: PDB Molecule:probable inorganic polyphosphate/atp-nad kinase; PDBTitle: crystal structure of a nad kinase from archaeoglobus2 fulgidus in complex with nad 120 d1z0sa1 not modelled 26.6 18 Fold:NAD kinase/diacylglycerol kinase-like Superfamily:NAD kinase/diacylglycerol kinase-like Family:NAD kinase-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0