Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	R	T	I	F	C	T	F	L	Q	R	E	A	E	G	Q	D	F	Q	L	Y	P	G	E	L	G	K	R	I	Y	N	E	I	S	K	E	A	W	A	Q	W	Q	H	K	Q	T	M	L	I	N	E	K	K	L	N	M	M	N	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?								?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.
Sequence		E	H	R	K	L	L	E	Q	E	M	V	N	F	L	F	E	G	K	E	V	H	I	E	G	Y	T	P	E	D	K	K
Secondary structure
SS confidence
Disorder															?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1xs8 chain A Region: 1 - 91 Aligned: 91 Modelled: 91 Confidence: 100.0% Identity: 95% Fold: YggX-like Superfamily: YggX-like Family: YggX-like Phyre2 PDB 1t07 chain A Region: 2 - 79 Aligned: 78 Modelled: 78 Confidence: 100.0% Identity: 47% Fold: YggX-like Superfamily: YggX-like Family: YggX-like Phyre2 PDB 2fxa chain A domain 1 Region: 20 - 57 Aligned: 37 Modelled: 38 Confidence: 37.4% Identity: 19% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: MarR-like transcriptional regulators Phyre2 PDB 2qm3 chain A Region: 39 - 59 Aligned: 21 Modelled: 21 Confidence: 32.8% Identity: 24% PDB header:transferase Chain: A: PDB Molecule:predicted methyltransferase; PDBTitle: crystal structure of a predicted methyltransferase from pyrococcus2 furiosus Phyre2 PDB 1fcd chain C domain 2 Region: 25 - 77 Aligned: 50 Modelled: 53 Confidence: 29.2% Identity: 14% Fold: Cytochrome c Superfamily: Cytochrome c Family: Two-domain cytochrome c Phyre2 PDB 2rfp chain A Region: 77 - 91 Aligned: 15 Modelled: 15 Confidence: 29.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:putative ntp pyrophosphohydrolase; PDBTitle: crystal structure of putative ntp pyrophosphohydrolase2 (yp_001813558.1) from exiguobacterium sibiricum 255-15 at 1.74 a3 resolution Phyre2 PDB 3mi6 chain A Region: 51 - 80 Aligned: 30 Modelled: 30 Confidence: 24.3% Identity: 10% PDB header:hydrolase Chain: A: PDB Molecule:alpha-galactosidase; PDBTitle: crystal structure of the alpha-galactosidase from lactobacillus2 brevis, northeast structural genomics consortium target lbr11. Phyre2 PDB 2xn1 chain B Region: 51 - 80 Aligned: 30 Modelled: 30 Confidence: 24.0% Identity: 27% PDB header:hydrolase Chain: B: PDB Molecule:alpha-galactosidase; PDBTitle: structure of alpha-galactosidase from lactobacillus acidophilus ncfm2 with tris Phyre2 PDB 2voy chain K Region: 27 - 36 Aligned: 10 Modelled: 10 Confidence: 23.4% Identity: 40% PDB header:hydrolase Chain: K: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus Phyre2 PDB 2yfn chain A Region: 51 - 80 Aligned: 30 Modelled: 30 Confidence: 23.1% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:alpha-galactosidase-sucrose kinase agask; PDBTitle: galactosidase domain of alpha-galactosidase-sucrose kinase,2 agask Phyre2 PDB 2yf3 chain F Region: 77 - 89 Aligned: 13 Modelled: 13 Confidence: 21.0% Identity: 46% PDB header:hydrolase Chain: F: PDB Molecule:mazg-like nucleoside triphosphate pyrophosphohydrolase; PDBTitle: crystal structure of dr2231, the mazg-like protein from2 deinococcus radiodurans, complex with manganese Phyre2 PDB 1cyj chain A Region: 25 - 38 Aligned: 14 Modelled: 14 Confidence: 20.6% Identity: 21% Fold: Cytochrome c Superfamily: Cytochrome c Family: monodomain cytochrome c Phyre2 PDB 1s29 chain A Region: 18 - 87 Aligned: 45 Modelled: 50 Confidence: 17.4% Identity: 13% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: La domain Phyre2 PDB 2ijr chain A domain 1 Region: 7 - 45 Aligned: 39 Modelled: 39 Confidence: 15.3% Identity: 13% Fold: Api92-like Superfamily: Api92-like Family: Api92-like Phyre2 PDB 1kb0 chain A domain 1 Region: 11 - 38 Aligned: 28 Modelled: 28 Confidence: 14.8% Identity: 14% Fold: Cytochrome c Superfamily: Cytochrome c Family: Quinoprotein alcohol dehydrogenase, C-terminal domain Phyre2 PDB 1u6r chain A domain 2 Region: 8 - 91 Aligned: 80 Modelled: 84 Confidence: 14.3% Identity: 16% Fold: Glutamine synthetase/guanido kinase Superfamily: Glutamine synthetase/guanido kinase Family: Guanido kinase catalytic domain Phyre2 PDB 1g0w chain A domain 2 Region: 8 - 91 Aligned: 80 Modelled: 82 Confidence: 13.4% Identity: 16% Fold: Glutamine synthetase/guanido kinase Superfamily: Glutamine synthetase/guanido kinase Family: Guanido kinase catalytic domain Phyre2 PDB 1ctj chain A Region: 25 - 38 Aligned: 14 Modelled: 14 Confidence: 13.4% Identity: 21% Fold: Cytochrome c Superfamily: Cytochrome c Family: monodomain cytochrome c Phyre2 PDB 1hbk chain A Region: 8 - 48 Aligned: 36 Modelled: 41 Confidence: 13.1% Identity: 11% Fold: Acyl-CoA binding protein-like Superfamily: Acyl-CoA binding protein Family: Acyl-CoA binding protein Phyre2 PDB 1vjg chain A Region: 23 - 42 Aligned: 20 Modelled: 20 Confidence: 12.8% Identity: 30% Fold: Flavodoxin-like Superfamily: SGNH hydrolase Family: Hypothetical protein alr1529 Phyre2 1 d1xs8a_ 2 d1t07a_ 3 d2fxaa1 4 c2qm3A_ 5 d1fcdc2 6 c2rfpA_ 7 c3mi6A_ 8 c2xn1B_ 9 c2voyK_ 10 c2yfnA_ 11 c2yf3F_ 12 d1cyja_ 13 d1s29a_ 14 d2ijra1 15 d1kb0a1 16 d1u6ra2 17 d1g0wa2 18 d1ctja_ 19 d1hbka_ 20 d1vjga_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1xs8a_ 100.0 95 Fold:YggX-like Superfamily:YggX-like Family:YggX-like 2 d1t07a_ 100.0 47 Fold:YggX-like Superfamily:YggX-like Family:YggX-like 3 d2fxaa1 37.4 19 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators 4 c2qm3A_ 32.8 24 PDB header:transferase Chain: A: PDB Molecule:predicted methyltransferase; PDBTitle: crystal structure of a predicted methyltransferase from pyrococcus2 furiosus 5 d1fcdc2 29.2 14 Fold:Cytochrome c Superfamily:Cytochrome c Family:Two-domain cytochrome c 6 c2rfpA_ 29.0 20 PDB header:hydrolase Chain: A: PDB Molecule:putative ntp pyrophosphohydrolase; PDBTitle: crystal structure of putative ntp pyrophosphohydrolase2 (yp_001813558.1) from exiguobacterium sibiricum 255-15 at 1.74 a3 resolution 7 c3mi6A_ 24.3 10 PDB header:hydrolase Chain: A: PDB Molecule:alpha-galactosidase; PDBTitle: crystal structure of the alpha-galactosidase from lactobacillus2 brevis, northeast structural genomics consortium target lbr11. 8 c2xn1B_ 24.0 27 PDB header:hydrolase Chain: B: PDB Molecule:alpha-galactosidase; PDBTitle: structure of alpha-galactosidase from lactobacillus acidophilus ncfm2 with tris 9 c2voyK_ 23.4 40 PDB header:hydrolase Chain: K: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus 10 c2yfnA_ 23.1 23 PDB header:hydrolase Chain: A: PDB Molecule:alpha-galactosidase-sucrose kinase agask; PDBTitle: galactosidase domain of alpha-galactosidase-sucrose kinase,2 agask 11 c2yf3F_ 21.0 46 PDB header:hydrolase Chain: F: PDB Molecule:mazg-like nucleoside triphosphate pyrophosphohydrolase; PDBTitle: crystal structure of dr2231, the mazg-like protein from2 deinococcus radiodurans, complex with manganese 12 d1cyja_ 20.6 21 Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c 13 d1s29a_ 17.4 13 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:La domain 14 d2ijra1 15.3 13 Fold:Api92-like Superfamily:Api92-like Family:Api92-like 15 d1kb0a1 14.8 14 Fold:Cytochrome c Superfamily:Cytochrome c Family:Quinoprotein alcohol dehydrogenase, C-terminal domain 16 d1u6ra2 14.3 16 Fold:Glutamine synthetase/guanido kinase Superfamily:Glutamine synthetase/guanido kinase Family:Guanido kinase catalytic domain 17 d1g0wa2 13.4 16 Fold:Glutamine synthetase/guanido kinase Superfamily:Glutamine synthetase/guanido kinase Family:Guanido kinase catalytic domain 18 d1ctja_ 13.4 21 Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c 19 d1hbka_ 13.1 11 Fold:Acyl-CoA binding protein-like Superfamily:Acyl-CoA binding protein Family:Acyl-CoA binding protein 20 d1vjga_ 12.8 30 Fold:Flavodoxin-like Superfamily:SGNH hydrolase Family:Hypothetical protein alr1529 21 d1xgsa1 not modelled 12.4 21 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Methionine aminopeptidase, insert domain 22 d1c6ra_ not modelled 11.5 21 Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c 23 c3fy6A_ not modelled 11.1 32 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:integron cassette protein; PDBTitle: structure from the mobile metagenome of v. cholerae.2 integron cassette protein vch_cass3 24 c2kw3C_ not modelled 10.8 24 PDB header:dna binding protein Chain: C: PDB Molecule:regulatory factor x-associated protein; PDBTitle: heterotrimeric interaction between rfx5 and rfxap 25 c2kktA_ not modelled 10.4 7 PDB header:transcription Chain: A: PDB Molecule:ataxin-7-like protein 3; PDBTitle: solution structure of the sca7 domain of human ataxin-7-l3 protein 26 d1ngka_ not modelled 9.9 18 Fold:Globin-like Superfamily:Globin-like Family:Truncated hemoglobin 27 d1gdva_ not modelled 9.9 7 Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c 28 d1o22a_ not modelled 9.8 31 Fold:Hypothetical protein TM0875 Superfamily:Hypothetical protein TM0875 Family:Hypothetical protein TM0875 29 d1zh5a1 not modelled 9.6 30 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:La domain 30 d1qc7a_ not modelled 9.4 18 Fold:alpha-alpha superhelix Superfamily:FliG Family:FliG 31 c2owlA_ not modelled 9.1 13 PDB header:recombination Chain: A: PDB Molecule:recombination-associated protein rdgc; PDBTitle: crystal structure of e. coli rdgc 32 d1jmxa5 not modelled 9.1 50 Fold:Streptavidin-like Superfamily:Quinohemoprotein amine dehydrogenase A chain, domain 3 Family:Quinohemoprotein amine dehydrogenase A chain, domain 3 33 c3o2iB_ not modelled 9.0 47 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of a functionally unknown protein from2 leptospirillum sp. group ii uba 34 d1alca_ not modelled 8.9 17 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:C-type lysozyme 35 d1f6sa_ not modelled 8.9 17 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:C-type lysozyme 36 d1ykha1 not modelled 8.8 25 Fold:Mediator hinge subcomplex-like Superfamily:Mediator hinge subcomplex-like Family:MED7 hinge region 37 d1hb6a_ not modelled 8.8 19 Fold:Acyl-CoA binding protein-like Superfamily:Acyl-CoA binding protein Family:Acyl-CoA binding protein 38 d1ls9a_ not modelled 8.8 14 Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c 39 c2z2fA_ not modelled 8.7 33 PDB header:hydrolase Chain: A: PDB Molecule:lysozyme c-2; PDBTitle: x-ray crystal structure of bovine stomach lysozyme 40 c3dr0B_ not modelled 8.6 7 PDB header:electron transport Chain: B: PDB Molecule:cytochrome c6; PDBTitle: structure of reduced cytochrome c6 from synechococcus sp.2 pcc 7002 41 c3zs9C_ not modelled 8.5 26 PDB header:hydrolase/transport protein Chain: C: PDB Molecule:golgi to er traffic protein 2; PDBTitle: s. cerevisiae get3-adp-alf4- complex with a cytosolic get2 fragment 42 d1f08a_ not modelled 8.3 44 Fold:Origin of replication-binding domain, RBD-like Superfamily:Origin of replication-binding domain, RBD-like Family:Replication initiation protein E1 43 d1co6a_ not modelled 8.1 8 Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c 44 d1qc7b_ not modelled 8.1 18 Fold:alpha-alpha superhelix Superfamily:FliG Family:FliG 45 d1r9wa_ not modelled 8.0 22 Fold:Origin of replication-binding domain, RBD-like Superfamily:Origin of replication-binding domain, RBD-like Family:Replication initiation protein E1 46 d1nira1 not modelled 7.8 21 Fold:Cytochrome c Superfamily:Cytochrome c Family:N-terminal (heme c) domain of cytochrome cd1-nitrite reductase 47 c1x31D_ not modelled 7.8 28 PDB header:oxidoreductase Chain: D: PDB Molecule:sarcosine oxidase delta subunit; PDBTitle: crystal structure of heterotetrameric sarcosine oxidase from2 corynebacterium sp. u-96 48 d1vrpa2 not modelled 7.8 15 Fold:Glutamine synthetase/guanido kinase Superfamily:Glutamine synthetase/guanido kinase Family:Guanido kinase catalytic domain 49 d1c52a_ not modelled 7.7 27 Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c 50 d1cc5a_ not modelled 7.7 8 Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c 51 d1gd6a_ not modelled 7.7 33 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:C-type lysozyme 52 c3flvA_ not modelled 7.6 28 PDB header:lipid binding protein Chain: A: PDB Molecule:acyl-coa-binding domain-containing protein 5; PDBTitle: the crystal structure of human acyl-coenzymea binding domain2 containing 5 53 d1iiza_ not modelled 7.5 33 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:C-type lysozyme 54 d1x68a2 not modelled 7.4 27 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:LIM domain 55 c3b08H_ not modelled 7.3 15 PDB header:signaling protein/metal binding protein Chain: H: PDB Molecule:ranbp-type and c3hc4-type zinc finger-containing protein 1; PDBTitle: crystal structure of the mouse hoil1-l-nzf in complex with linear di-2 ubiquitin 56 d1juga_ not modelled 7.3 33 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:C-type lysozyme 57 c3cu4A_ not modelled 7.3 8 PDB header:electron transport Chain: A: PDB Molecule:cytochrome c family protein; PDBTitle: omcf, outer membrance cytochrome f from geobacter2 sulfurreducens 58 d1jmxa1 not modelled 7.3 10 Fold:Cytochrome c Superfamily:Cytochrome c Family:Quinohemoprotein amine dehydrogenase A chain, domains 1 and 2 59 d1h4ra3 not modelled 7.2 13 Fold:beta-Grasp (ubiquitin-like) Superfamily:Ubiquitin-like Family:First domain of FERM 60 c2wh5A_ not modelled 7.1 22 PDB header:lipid binding protein Chain: A: PDB Molecule:acyl-coa-binding domain-containing protein 4; PDBTitle: crystal structure of human acyl-coa binding domain 42 complexed with stearoyl-coa 61 d2dloa2 not modelled 7.0 31 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:LIM domain 62 d1f1fa_ not modelled 7.0 7 Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c 63 d1f1ca_ not modelled 6.9 14 Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c 64 d1kv9a1 not modelled 6.8 21 Fold:Cytochrome c Superfamily:Cytochrome c Family:Quinoprotein alcohol dehydrogenase, C-terminal domain 65 c2cfhA_ not modelled 6.7 16 PDB header:transport Chain: A: PDB Molecule:trafficking protein particle complex subunit 3; PDBTitle: structure of the bet3-tpc6b core of trapp 66 c2zonG_ not modelled 6.6 17 PDB header:oxidoreductase/electron transport Chain: G: PDB Molecule:cytochrome c551; PDBTitle: crystal structure of electron transfer complex of nitrite2 reductase with cytochrome c 67 d1b9oa_ not modelled 6.6 17 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:C-type lysozyme 68 c3fo8D_ not modelled 6.5 37 PDB header:viral protein Chain: D: PDB Molecule:tail sheath protein gp18; PDBTitle: crystal structure of the bacteriophage t4 tail sheath2 protein, protease resistant fragment gp18pr 69 c2v07A_ not modelled 6.5 14 PDB header:photosynthesis Chain: A: PDB Molecule:cytochrome c6; PDBTitle: structure of the arabidopsis thaliana cytochrome c6a v52q2 variant 70 d1ef1a3 not modelled 6.4 27 Fold:beta-Grasp (ubiquitin-like) Superfamily:Ubiquitin-like Family:First domain of FERM 71 c2crcA_ not modelled 6.4 15 PDB header:ligase Chain: A: PDB Molecule:ubiquitin conjugating enzyme 7 interacting PDBTitle: solution structure of the zf-ranbp domain of the protein2 hbv associated factor 72 c3epyA_ not modelled 6.3 19 PDB header:lipid binding protein Chain: A: PDB Molecule:acyl-coa-binding domain-containing protein 7; PDBTitle: crystal structure of human acyl-coa binding domain 72 complexed with palmitoyl-coa 73 d2nwdx1 not modelled 6.2 28 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:C-type lysozyme 74 d1gg3a3 not modelled 6.1 7 Fold:beta-Grasp (ubiquitin-like) Superfamily:Ubiquitin-like Family:First domain of FERM 75 d2q9oa3 not modelled 5.9 13 Fold:Cupredoxin-like Superfamily:Cupredoxins Family:Multidomain cupredoxins 76 c2wweA_ not modelled 5.9 15 PDB header:transferase Chain: A: PDB Molecule:phosphoinositide-3-kinase, class 2, gamma PDBTitle: crystal structure of the phox homology domain of human2 phosphoinositide-3-kinase-c2-gamma 77 d1e29a_ not modelled 5.9 17 Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c 78 d1wvec1 not modelled 5.8 25 Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c 79 d2c8sa1 not modelled 5.6 7 Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c 80 d1hfxa_ not modelled 5.6 17 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:C-type lysozyme 81 c2goiC_ not modelled 5.5 28 PDB header:cell adhesion, sugar binding protein Chain: C: PDB Molecule:sperm lysozyme-like protein 1; PDBTitle: crystal structure of mouse sperm c-type lysozyme-like2 protein 1 82 c2kjeB_ not modelled 5.5 38 PDB header:transcription Chain: B: PDB Molecule:early e1a 32 kda protein; PDBTitle: nmr structure of cbp taz2 and adenoviral e1a complex 83 d1yroa1 not modelled 5.5 17 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:C-type lysozyme 84 d2zpya3 not modelled 5.4 27 Fold:beta-Grasp (ubiquitin-like) Superfamily:Ubiquitin-like Family:First domain of FERM 85 d1ghla_ not modelled 5.2 28 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:C-type lysozyme 86 c3cp5A_ not modelled 5.2 14 PDB header:electron transport Chain: A: PDB Molecule:cytochrome c; PDBTitle: cytochrome c from rhodothermus marinus

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0