Email l.a.kelley@imperial.ac.uk Description P76346 Date Wed Jan 25 15:21:07 GMT 2012 Unique Job ID 25100d9bb99ddaaf

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3dl1A_ 100.0 80 PDB header:hydrolase Chain: A: PDB Molecule:putative metal-dependent hydrolase; PDBTitle: crystal structure of a putative metal-dependent hydrolase2 (yp_001336084.1) from klebsiella pneumoniae subsp. pneumoniae mgh3 78578 at 2.20 a resolution 2 c2l0rA_ 99.8 18 PDB header:hydrolase,toxin Chain: A: PDB Molecule:lethal factor; PDBTitle: conformational dynamics of the anthrax lethal factor catalytic center 3 d1j7na2 99.8 16 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Anthrax toxin lethal factor, N- and C-terminal domains 4 c1yqyA_ 97.2 21 PDB header:hydrolase Chain: A: PDB Molecule:lethal factor; PDBTitle: structure of b. anthrax lethal factor in complex with a2 hydroxamate inhibitor 5 c1pwqA_ 97.2 20 PDB header:hydrolase Chain: A: PDB Molecule:lethal factor; PDBTitle: crystal structure of anthrax lethal factor complexed with2 thioacetyl-tyr-pro-met-amide, a metal-chelating peptidyl3 small molecule inhibitor 6 d2ejqa1 84.6 13 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:TTHA0227-like 7 c2xpyA_ 64.6 17 PDB header:hydrolase Chain: A: PDB Molecule:leukotriene a-4 hydrolase; PDBTitle: structure of native leukotriene a4 hydrolase from saccharomyces2 cerevisiae 8 c3lq0A_ 59.9 14 PDB header:hydrolase Chain: A: PDB Molecule:proastacin; PDBTitle: zymogen structure of crayfish astacin metallopeptidase 9 d1hv5a_ 57.3 29 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 10 d1qiba_ 55.8 36 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 11 d1i76a_ 53.6 42 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 12 d1k7ia2 53.2 23 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 13 d1hfca_ 53.1 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 14 d1kapp2 52.4 31 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 15 d1q3aa_ 52.2 42 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 16 d1asta_ 51.5 50 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Astacin 17 d1mmqa_ 51.2 29 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 18 d1cxva_ 50.4 36 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 19 c3edhA_ 50.3 30 PDB header:hydrolase Chain: A: PDB Molecule:bone morphogenetic protein 1; PDBTitle: crystal structure of bone morphogenetic protein 1 protease2 domain in complex with partially bound dmso 20 c3ciaA_ 48.9 30 PDB header:hydrolase Chain: A: PDB Molecule:cold-active aminopeptidase; PDBTitle: crystal structure of cold-aminopeptidase from colwellia2 psychrerythraea 21 d1cgla_ not modelled 48.5 36 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 22 d1y93a1 not modelled 48.0 36 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 23 d2ixoa1 not modelled 48.0 15 Fold:PTPA-like Superfamily:PTPA-like Family:PTPA-like 24 d1g9ka2 not modelled 47.8 22 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 25 c3lqbA_ not modelled 47.4 40 PDB header:hydrolase Chain: A: PDB Molecule:loc792177 protein; PDBTitle: crystal structure of the hatching enzyme zhe1 from the zebrafish danio2 rerio 26 d1hy7a_ not modelled 47.3 36 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 27 d1bqqm_ not modelled 46.4 36 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 28 d1fbla2 not modelled 45.6 28 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 29 c2xs4A_ not modelled 45.6 33 PDB header:hydrolase Chain: A: PDB Molecule:karilysin protease; PDBTitle: structure of karilysin catalytic mmp domain in complex with2 magnesium 30 d1eaka2 not modelled 45.5 15 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 31 c2jsdA_ not modelled 44.9 42 PDB header:hydrolase Chain: A: PDB Molecule:matrix metalloproteinase-20; PDBTitle: solution structure of mmp20 complexed with nngh 32 d1xuca1 not modelled 44.8 42 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 33 d1hova_ not modelled 44.6 19 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 34 d1rm8a_ not modelled 44.6 36 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 35 d2ovxa1 not modelled 44.4 36 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 36 c1su3A_ not modelled 41.5 33 PDB header:hydrolase Chain: A: PDB Molecule:interstitial collagenase; PDBTitle: x-ray structure of human prommp-1: new insights into2 collagenase action 37 d1sata2 not modelled 41.3 17 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 38 c3ba0A_ not modelled 40.3 36 PDB header:hydrolase Chain: A: PDB Molecule:macrophage metalloelastase; PDBTitle: crystal structure of full-length human mmp-12 39 c3b4rB_ not modelled 40.2 30 PDB header:hydrolase Chain: B: PDB Molecule:putative zinc metalloprotease mj0392; PDBTitle: site-2 protease from methanocaldococcus jannaschii 40 c1slmA_ not modelled 39.7 42 PDB header:hydrolase Chain: A: PDB Molecule:stromelysin-1; PDBTitle: crystal structure of fibroblast stromelysin-1: the c-truncated human2 proenzyme 41 d2ixna1 not modelled 36.7 16 Fold:PTPA-like Superfamily:PTPA-like Family:PTPA-like 42 c1jiwP_ not modelled 36.3 22 PDB header:hydrolase/hyrolase inhibitor Chain: P: PDB Molecule:alkaline metalloproteinase; PDBTitle: crystal structure of the apr-aprin complex 43 c3d7iB_ not modelled 35.2 17 PDB header:lyase Chain: B: PDB Molecule:carboxymuconolactone decarboxylase family protein; PDBTitle: crystal structure of carboxymuconolactone decarboxylase family protein2 possibly involved in oxygen detoxification (1591455) from3 methanococcus jannaschii at 1.75 a resolution 44 d1kjpa_ not modelled 34.6 27 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 45 d1lmla_ not modelled 33.9 42 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Leishmanolysin 46 c2cltB_ not modelled 33.8 21 PDB header:hydrolase Chain: B: PDB Molecule:interstitial collagenase; PDBTitle: crystal structure of the active form (full-length) of human2 fibroblast collagenase. 47 d1bqba_ not modelled 33.3 18 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 48 c1y791_ not modelled 32.8 27 PDB header:hydrolase Chain: 1: PDB Molecule:peptidyl-dipeptidase dcp; PDBTitle: crystal structure of the e.coli dipeptidyl carboxypeptidase2 dcp in complex with a peptidic inhibitor 49 c1eakA_ not modelled 32.6 10 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:72 kda type iv collagenase; PDBTitle: catalytic domain of prommp-2 e404q mutant 50 d3e11a1 not modelled 29.3 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:TTHA0227-like 51 c3b7uX_ not modelled 29.0 32 PDB header:hydrolase Chain: X: PDB Molecule:leukotriene a-4 hydrolase; PDBTitle: leukotriene a4 hydrolase complexed with kelatorphan 52 c1l6jA_ not modelled 23.8 16 PDB header:hydrolase Chain: A: PDB Molecule:matrix metalloproteinase-9; PDBTitle: crystal structure of human matrix metalloproteinase mmp92 (gelatinase b). 53 c1om8A_ not modelled 23.6 38 PDB header:hydrolase Chain: A: PDB Molecule:serralysin; PDBTitle: crystal structure of a cold adapted alkaline protease from pseudomonas2 tac ii 18, co-crystallyzed with 10 mm edta 54 d1neka3 not modelled 23.1 24 Fold:Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Superfamily:Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Family:Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 55 c2j83B_ not modelled 22.5 18 PDB header:hydrolase Chain: B: PDB Molecule:ulilysin; PDBTitle: ulilysin metalloprotease in complex with batimastat. 56 c3c0hB_ not modelled 21.4 10 PDB header:transferase Chain: B: PDB Molecule:peripheral plasma membrane protein cask; PDBTitle: cask cam-kinase domain- amppnp complex, p1 form 57 c1satA_ not modelled 20.8 17 PDB header:hydrolase (serine protease) Chain: A: PDB Molecule:serratia protease; PDBTitle: crystal structure of the 50 kda metallo protease from s.2 marcescens 58 d3b7sa3 not modelled 20.0 40 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Leukotriene A4 hydrolase catalytic domain 59 c2oqjL_ not modelled 19.0 50 PDB header:immune system Chain: L: PDB Molecule:peptide 2g12.1 (acppshvldmrsgtclaaegk); PDBTitle: crystal structure analysis of fab 2g12 in complex with peptide 2g12.1 60 c2oqjC_ not modelled 18.9 50 PDB header:immune system Chain: C: PDB Molecule:peptide 2g12.1 (acppshvldmrsgtclaaegk); PDBTitle: crystal structure analysis of fab 2g12 in complex with peptide 2g12.1 61 d1kufa_ not modelled 18.8 23 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 62 c2oqjI_ not modelled 18.7 50 PDB header:immune system Chain: I: PDB Molecule:peptide 2g12.1 (acppshvldmrsgtclaaegk); PDBTitle: crystal structure analysis of fab 2g12 in complex with peptide 2g12.1 63 c3k7lA_ not modelled 17.9 29 PDB header:hydrolase Chain: A: PDB Molecule:atragin; PDBTitle: structures of two elapid snake venom metalloproteases with2 distinct activities highlight the disulfide patterns in the3 d domain of adamalysin family proteins 64 d2ixma1 not modelled 17.8 18 Fold:PTPA-like Superfamily:PTPA-like Family:PTPA-like 65 c2gtqA_ not modelled 17.7 30 PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase n; PDBTitle: crystal structure of aminopeptidase n from human pathogen neisseria2 meningitidis 66 d1npca_ not modelled 16.7 20 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 67 c2g62A_ not modelled 16.4 22 PDB header:hydrolase activator Chain: A: PDB Molecule:protein phosphatase 2a, regulatory subunit b' (pr 53); PDBTitle: crystal structure of human ptpa 68 c2oqjF_ not modelled 15.7 50 PDB header:immune system Chain: F: PDB Molecule:peptide 2g12.1 (acppshvldmrsgtclaaegk); PDBTitle: crystal structure analysis of fab 2g12 in complex with peptide 2g12.1 69 c2erpA_ not modelled 15.4 29 PDB header:toxin Chain: A: PDB Molecule:vascular apoptosis-inducing protein 1; PDBTitle: crystal structure of vascular apoptosis-inducing protein-1(inhibitor-2 bound form) 70 c3k7nA_ not modelled 15.3 36 PDB header:hydrolase Chain: A: PDB Molecule:k-like; PDBTitle: structures of two elapid snake venom metalloproteases with2 distinct activities highlight the disulfide patterns in the3 d domain of adamalysin family proteins 71 c3ebhA_ not modelled 14.9 30 PDB header:hydrolase inhibitor Chain: A: PDB Molecule:m1 family aminopeptidase; PDBTitle: structure of the m1 alanylaminopeptidase from malaria complexed with2 bestatin 72 d1wlfa2 not modelled 14.8 27 Fold:Double psi beta-barrel Superfamily:ADC-like Family:Cdc48 N-terminal domain-like 73 c2c1iA_ not modelled 14.7 14 PDB header:hydrolase Chain: A: PDB Molecule:peptidoglycan glcnac deacetylase; PDBTitle: structure of streptococcus pnemoniae peptidoglycan2 deacetylase (sppgda) d 275 n mutant. 74 c2i47A_ not modelled 14.7 21 PDB header:hydrolase Chain: A: PDB Molecule:adam 17; PDBTitle: crystal structure of catalytic domain of tace with inhibitor 75 c1wgzC_ not modelled 14.5 17 PDB header:hydrolase Chain: C: PDB Molecule:carboxypeptidase 1; PDBTitle: crystal structure of carboxypeptidase 1 from thermus thermophilus 76 c2c30A_ not modelled 14.2 17 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase pak 6; PDBTitle: crystal structure of the human p21-activated kinase 6 77 c3b37A_ not modelled 13.9 40 PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase n; PDBTitle: crystal structure of e. coli aminopeptidase n in complex with tyrosine 78 d2i47a1 not modelled 13.6 21 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:TNF-alpha converting enzyme, TACE, catalytic domain 79 c3ppuB_ not modelled 13.2 13 PDB header:transferase Chain: B: PDB Molecule:glutathione-s-transferase; PDBTitle: crystal structure of the glutathione-s-transferase xi from2 phanerochaete chrysosporium 80 c1yp1A_ not modelled 13.1 27 PDB header:hydrolase Chain: A: PDB Molecule:fii; PDBTitle: crystal structure of a non-hemorrhagic fibrin(ogen)olytic2 metalloproteinase from venom of agkistrodon acutus 81 d2ajfa1 not modelled 12.9 11 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Neurolysin-like 82 d1nd1a_ not modelled 12.9 29 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 83 c3famA_ not modelled 12.8 16 PDB header:transferase Chain: A: PDB Molecule:carbon catabolite-derepressing protein kinase; PDBTitle: crystal structure of the protein kinase domain of yeast amp-2 activated protein kinase snf1 84 c1yyeA_ not modelled 12.8 14 PDB header:transcription Chain: A: PDB Molecule:estrogen receptor beta; PDBTitle: crystal structure of estrogen receptor beta complexed with2 way-202196 85 d1eb6a_ not modelled 12.5 16 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Fungal zinc peptidase 86 c1z5hB_ not modelled 12.4 60 PDB header:hydrolase Chain: B: PDB Molecule:tricorn protease interacting factor f3; PDBTitle: crystal structures of the tricorn interacting factor f32 from thermoplasma acidophilum 87 c2v4bB_ not modelled 12.3 21 PDB header:hydrolase Chain: B: PDB Molecule:adamts-1; PDBTitle: crystal structure of human adamts-1 catalytic domain and2 cysteine-rich domain (apo-form) 88 c3cqbB_ not modelled 12.2 15 PDB header:hydrolase Chain: B: PDB Molecule:probable protease htpx homolog; PDBTitle: crystal structure of heat shock protein htpx domain from vibrio2 parahaemolyticus rimd 2210633 89 d1phka_ not modelled 12.2 9 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 90 c2e3xA_ not modelled 12.2 29 PDB header:hydrolase, blood clotting, toxin Chain: A: PDB Molecule:coagulation factor x-activating enzyme heavy chain; PDBTitle: crystal structure of russell's viper venom metalloproteinase 91 c3g5cA_ not modelled 12.1 14 PDB header:membrane protein Chain: A: PDB Molecule:adam 22; PDBTitle: structural and biochemical studies on the ectodomain of human adam22 92 c3nqzB_ not modelled 11.9 20 PDB header:hydrolase Chain: B: PDB Molecule:secreted metalloprotease mcp02; PDBTitle: crystal structure of the autoprocessed vibriolysin mcp-02 with e369a2 mutation 93 d1atla_ not modelled 11.9 29 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 94 c3b8zB_ not modelled 11.8 29 PDB header:hydrolase Chain: B: PDB Molecule:protein adamts-5; PDBTitle: high resolution crystal structure of the catalytic domain2 of adamts-5 (aggrecanase-2) 95 d1chua3 not modelled 11.8 14 Fold:Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Superfamily:Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Family:Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 96 c3ce2A_ not modelled 11.7 36 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative peptidase; PDBTitle: crystal structure of putative peptidase from chlamydophila abortus 97 c2rjpC_ not modelled 11.5 14 PDB header:hydrolase Chain: C: PDB Molecule:adamts-4; PDBTitle: crystal structure of adamts4 with inhibitor bound 98 c2rjqA_ not modelled 11.3 29 PDB header:hydrolase Chain: A: PDB Molecule:adamts-5; PDBTitle: crystal structure of adamts5 with inhibitor bound 99 c2dw1B_ not modelled 11.3 29 PDB header:apoptosis, toxin Chain: B: PDB Molecule:catrocollastatin; PDBTitle: crystal structure of vap2 from crotalus atrox venom (form 2-2 crystal)