Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	L	T	L	K	E	S	L	V	T	R	S	R	V	F	S	P	W	T	A	F	Y	F	L	Q	S	L	L	I	N	L	G	L	G	Y	P	F	S	L	L	Y	T	A	A	F	T	A	I	L	L	L	L	W	R	T	L	P	R	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	K	V	L	V	G	V	S	S	L	V	A	A	C	Y	F	P	F	A	Q	A	Y	G	A	P	N	F	N	T	L	L	A	L	H	S	T	N	M	E	E	S	T	E	I	L	T	I	F	P	W	Y	S	Y	L	V	G	L	F	I	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	L	G	V	I	A	I	R	R	K	K	E	N	E	K	A	R	W	N	T	F	D	S	L	C	L	V	F	S	V	A	T	F	F	V	A	P	V	Q	N	L	A	W	G	G	V	F	K	L	K	D	T	G	Y	P	V	F	R	F	A
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?	?																									?	?	?	?	?	?		?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		K	D	V	I	V	N	N	N	E	V	I	E	E	Q	E	R	M	A	K	L	S	G	M	K	D	T	W	T	V	T	A	V	K	P	K	Y	Q	T	Y	V	V	V	I	G	E	S	A	R	R	D	A	L	G	A	F	G	G	H	W	D
Secondary structure
SS confidence
Disorder																					?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		N	T	P	F	A	S	S	V	N	G	L	I	F	A	D	Y	I	A	A	S	G	S	T	Q	K	S	L	G	L	T	L	N	R	V	V	D	G	K	P	Q	F	Q	D	N	F	V	T	L	A	N	R	A	G	F	Q	T	W	W	F	S
Secondary structure
SS confidence
Disorder																																?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		N	Q	G	Q	I	G	E	Y	D	T	A	I	A	S	I	A	K	R	A	D	E	V	Y	F	L	K	E	G	N	F	E	A	D	K	N	T	K	D	E	A	L	L	D	M	T	A	Q	V	L	A	Q	E	H	S	Q	P	Q	L	I	V
Secondary structure
SS confidence
Disorder				?																												?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		L	H	L	M	G	S	H	P	Q	A	C	D	R	T	Q	G	K	Y	E	T	F	V	Q	S	K	E	T	S	C	Y	L	Y	T	M	T	Q	T	D	D	L	L	R	K	L	Y	D	Q	L	R	N	S	G	S	S	F	S	L	V	Y	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		S	D	H	G	L	A	F	K	E	R	G	K	D	V	Q	Y	L	A	H	D	D	K	Y	Q	Q	N	F	Q	V	P	F	M	V	I	S	S	D	D	K	A	H	R	V	I	K	A	R	R	S	A	N	D	F	L	G	F	F	S	Q	W
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?	?			?	?	?	?	?	?	?	?	?														?	?						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.
Sequence		T	G	I	K	A	K	E	I	N	I	K	Y	P	F	I	S	E	K	K	A	G	P	I	Y	I	T	N	F	Q	L	Q	K	V	D	Y	N	H	L	G	T	D	I	F	D	P	K	P
Secondary structure
SS confidence
Disorder									?																																	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2w8d chain B Region: 193 - 526 Aligned: 332 Modelled: 334 Confidence: 100.0% Identity: 13% PDB header:transferase Chain: B: PDB Molecule:processed glycerol phosphate lipoteichoic acid synthase 2; PDBTitle: distinct and essential morphogenic functions for wall- and2 lipo-teichoic acids in bacillus subtilis Phyre2 PDB 2w5t chain A Region: 193 - 526 Aligned: 332 Modelled: 334 Confidence: 100.0% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:processed glycerol phosphate lipoteichoic acid PDBTitle: structure-based mechanism of lipoteichoic acid synthesis by2 staphylococcus aureus ltas. Phyre2 PDB 3lxq chain B Region: 184 - 506 Aligned: 309 Modelled: 316 Confidence: 100.0% Identity: 14% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp1736; PDBTitle: the crystal structure of a protein in the alkaline2 phosphatase superfamily from vibrio parahaemolyticus to3 1.95a Phyre2 PDB 3ed4 chain A Region: 216 - 526 Aligned: 311 Modelled: 311 Confidence: 100.0% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:arylsulfatase; PDBTitle: crystal structure of putative arylsulfatase from escherichia coli Phyre2 PDB 2qzu chain A Region: 211 - 495 Aligned: 281 Modelled: 285 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of the putative sulfatase yidj from bacteroides2 fragilis. northeast structural genomics consortium target bfr123 Phyre2 PDB 1fsu chain A Region: 214 - 527 Aligned: 311 Modelled: 313 Confidence: 100.0% Identity: 14% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 1auk chain A Region: 215 - 495 Aligned: 275 Modelled: 281 Confidence: 100.0% Identity: 13% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 3b5q chain B Region: 215 - 495 Aligned: 275 Modelled: 281 Confidence: 100.0% Identity: 14% PDB header:hydrolase Chain: B: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of a putative sulfatase (np_810509.1)2 from bacteroides thetaiotaomicron vpi-5482 at 2.40 a3 resolution Phyre2 PDB 1hdh chain A Region: 215 - 495 Aligned: 276 Modelled: 281 Confidence: 100.0% Identity: 19% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 2vqr chain A Region: 216 - 495 Aligned: 274 Modelled: 280 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase; PDBTitle: crystal structure of a phosphonate monoester hydrolase2 from rhizobium leguminosarum: a new member of the3 alkaline phosphatase superfamily Phyre2 PDB 1p49 chain A Region: 213 - 495 Aligned: 277 Modelled: 283 Confidence: 100.0% Identity: 15% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 1o98 chain A domain 2 Region: 216 - 495 Aligned: 256 Modelled: 264 Confidence: 100.0% Identity: 9% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain Phyre2 PDB 2i09 chain A domain 1 Region: 214 - 495 Aligned: 233 Modelled: 255 Confidence: 100.0% Identity: 12% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: DeoB catalytic domain-like Phyre2 PDB 3m8y chain C Region: 215 - 496 Aligned: 251 Modelled: 271 Confidence: 100.0% Identity: 18% PDB header:isomerase Chain: C: PDB Molecule:phosphopentomutase; PDBTitle: phosphopentomutase from bacillus cereus after glucose-1,6-bisphosphate2 activation Phyre2 PDB 2zkt chain B Region: 216 - 484 Aligned: 246 Modelled: 269 Confidence: 100.0% Identity: 14% PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-independent phosphoglycerate PDBTitle: structure of ph0037 protein from pyrococcus horikoshii Phyre2 PDB 3q3q chain A Region: 212 - 494 Aligned: 270 Modelled: 283 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: crystal structure of spap: an novel alkaline phosphatase from2 bacterium sphingomonas sp. strain bsar-1 Phyre2 PDB 2gso chain B Region: 215 - 495 Aligned: 250 Modelled: 281 Confidence: 99.9% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:phosphodiesterase-nucleotide pyrophosphatase; PDBTitle: structure of xac nucleotide2 pyrophosphatase/phosphodiesterase in complex with vanadate Phyre2 PDB 2i09 chain A Region: 279 - 495 Aligned: 173 Modelled: 200 Confidence: 99.9% Identity: 13% PDB header:isomerase Chain: A: PDB Molecule:phosphopentomutase; PDBTitle: crystal structure of putative phosphopentomutase from streptococcus2 mutans Phyre2 PDB 3szz chain A Region: 210 - 478 Aligned: 253 Modelled: 253 Confidence: 99.9% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:phosphonoacetate hydrolase; PDBTitle: crystal structure of phosphonoacetate hydrolase from sinorhizobium2 meliloti 1021 in complex with acetate Phyre2 PDB 2xr9 chain A Region: 203 - 491 Aligned: 243 Modelled: 258 Confidence: 99.9% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) Phyre2 1 c2w8dB_ 2 c2w5tA_ 3 c3lxqB_ 4 c3ed4A_ 5 c2qzuA_ 6 d1fsua_ 7 d1auka_ 8 c3b5qB_ 9 d1hdha_ 10 c2vqrA_ 11 d1p49a_ 12 d1o98a2 13 d2i09a1 14 c3m8yC_ 15 c2zktB_ 16 c3q3qA_ 17 c2gsoB_ 18 c2i09A_ 19 c3szzA_ 20 c2xr9A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2w8dB_ 100.0 13 PDB header:transferase Chain: B: PDB Molecule:processed glycerol phosphate lipoteichoic acid synthase 2; PDBTitle: distinct and essential morphogenic functions for wall- and2 lipo-teichoic acids in bacillus subtilis 2 c2w5tA_ 100.0 13 PDB header:transferase Chain: A: PDB Molecule:processed glycerol phosphate lipoteichoic acid PDBTitle: structure-based mechanism of lipoteichoic acid synthesis by2 staphylococcus aureus ltas. 3 c3lxqB_ 100.0 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp1736; PDBTitle: the crystal structure of a protein in the alkaline2 phosphatase superfamily from vibrio parahaemolyticus to3 1.95a 4 c3ed4A_ 100.0 15 PDB header:transferase Chain: A: PDB Molecule:arylsulfatase; PDBTitle: crystal structure of putative arylsulfatase from escherichia coli 5 c2qzuA_ 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of the putative sulfatase yidj from bacteroides2 fragilis. northeast structural genomics consortium target bfr123 6 d1fsua_ 100.0 14 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 7 d1auka_ 100.0 13 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 8 c3b5qB_ 100.0 14 PDB header:hydrolase Chain: B: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of a putative sulfatase (np_810509.1)2 from bacteroides thetaiotaomicron vpi-5482 at 2.40 a3 resolution 9 d1hdha_ 100.0 19 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 10 c2vqrA_ 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase; PDBTitle: crystal structure of a phosphonate monoester hydrolase2 from rhizobium leguminosarum: a new member of the3 alkaline phosphatase superfamily 11 d1p49a_ 100.0 15 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 12 d1o98a2 100.0 9 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain 13 d2i09a1 100.0 12 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:DeoB catalytic domain-like 14 c3m8yC_ 100.0 18 PDB header:isomerase Chain: C: PDB Molecule:phosphopentomutase; PDBTitle: phosphopentomutase from bacillus cereus after glucose-1,6-bisphosphate2 activation 15 c2zktB_ 100.0 14 PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-independent phosphoglycerate PDBTitle: structure of ph0037 protein from pyrococcus horikoshii 16 c3q3qA_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: crystal structure of spap: an novel alkaline phosphatase from2 bacterium sphingomonas sp. strain bsar-1 17 c2gsoB_ 99.9 18 PDB header:hydrolase Chain: B: PDB Molecule:phosphodiesterase-nucleotide pyrophosphatase; PDBTitle: structure of xac nucleotide2 pyrophosphatase/phosphodiesterase in complex with vanadate 18 c2i09A_ 99.9 13 PDB header:isomerase Chain: A: PDB Molecule:phosphopentomutase; PDBTitle: crystal structure of putative phosphopentomutase from streptococcus2 mutans 19 c3szzA_ 99.9 15 PDB header:hydrolase Chain: A: PDB Molecule:phosphonoacetate hydrolase; PDBTitle: crystal structure of phosphonoacetate hydrolase from sinorhizobium2 meliloti 1021 in complex with acetate 20 c2xr9A_ 99.9 15 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) 21 c2xrgA_ not modelled 99.9 15 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor 22 d1ei6a_ not modelled 99.8 11 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Phosphonoacetate hydrolase 23 c1o98A_ not modelled 99.7 12 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: 1.4a crystal structure of phosphoglycerate mutase from2 bacillus stearothermophilus complexed with3 2-phosphoglycerate 24 c2d1gB_ not modelled 99.6 16 PDB header:hydrolase Chain: B: PDB Molecule:acid phosphatase; PDBTitle: structure of francisella tularensis acid phosphatase a (acpa) bound to2 orthovanadate 25 c3igzB_ not modelled 99.5 12 PDB header:isomerase Chain: B: PDB Molecule:cofactor-independent phosphoglycerate mutase; PDBTitle: crystal structures of leishmania mexicana phosphoglycerate2 mutase at low cobalt concentration 26 c2iucB_ not modelled 99.2 12 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: structure of alkaline phosphatase from the antarctic2 bacterium tab5 27 c2w0yB_ not modelled 99.0 13 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase 28 d1y6va1 not modelled 99.0 13 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 29 c2x98A_ not modelled 98.9 16 PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase 30 d1zeda1 not modelled 98.8 12 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 31 c1ew2A_ not modelled 98.8 11 PDB header:hydrolase Chain: A: PDB Molecule:phosphatase; PDBTitle: crystal structure of a human phosphatase 32 c3a52A_ not modelled 98.6 12 PDB header:hydrolase Chain: A: PDB Molecule:cold-active alkaline phosphatase; PDBTitle: crystal structure of cold-active alkailne phosphatase from2 psychrophile shewanella sp. 33 d1k7ha_ not modelled 98.6 11 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 34 c3e2dB_ not modelled 98.5 14 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: the 1.4 a crystal structure of the large and cold-active2 vibrio sp. alkaline phosphatase 35 c3iddA_ not modelled 91.1 18 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: cofactor-independent phosphoglycerate mutase from2 thermoplasma acidophilum dsm 1728 36 c3bijC_ not modelled 45.1 12 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein gsu0716; PDBTitle: crystal structure of protein gsu0716 from geobacter2 sulfurreducens. northeast structural genomics target gsr13 37 d1uzdc1 not modelled 43.1 24 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 38 d1b4ub_ not modelled 36.8 11 Fold:Phosphorylase/hydrolase-like Superfamily:LigB-like Family:LigB-like 39 d1ej7s_ not modelled 35.1 20 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 40 d8ruci_ not modelled 29.9 26 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 41 d2z1aa2 not modelled 27.0 11 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain 42 c2jcmA_ not modelled 24.3 29 PDB header:hydrolase Chain: A: PDB Molecule:cytosolic purine 5'-nucleotidase; PDBTitle: crystal structure of human cytosolic 5'-nucleotidase ii in2 complex with beryllium trifluoride 43 c2xokG_ not modelled 21.9 21 PDB header:hydrolase Chain: G: PDB Molecule:atp synthase subunit gamma, mitochondrial; PDBTitle: refined structure of yeast f1c10 atpase complex to 3 a2 resolution 44 c3e4cB_ not modelled 19.8 17 PDB header:hydrolase Chain: B: PDB Molecule:caspase-1; PDBTitle: procaspase-1 zymogen domain crystal strucutre 45 d1l5oa_ not modelled 18.3 42 Fold:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Superfamily:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Family:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) 46 d1j33a_ not modelled 17.2 33 Fold:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Superfamily:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Family:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) 47 c3uoaB_ not modelled 16.9 18 PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:mucosa-associated lymphoid tissue lymphoma translocation PDBTitle: crystal structure of the malt1 paracaspase (p21 form) 48 d2dlxa1 not modelled 16.7 4 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:UAS domain 49 d1xo1a2 not modelled 15.2 12 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 50 d1s1qa_ not modelled 14.8 8 Fold:UBC-like Superfamily:UBC-like Family:UEV domain 51 d2bdea1 not modelled 13.0 29 Fold:HAD-like Superfamily:HAD-like Family:5' nucleotidase-like 52 d2fiqa1 not modelled 12.9 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:GatZ-like 53 d1a8la1 not modelled 11.8 18 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 54 c2xmoB_ not modelled 11.5 7 PDB header:hydrolase Chain: B: PDB Molecule:lmo2642 protein; PDBTitle: the crystal structure of lmo2642 55 d2iuba2 not modelled 10.0 25 Fold:Transmembrane helix hairpin Superfamily:Magnesium transport protein CorA, transmembrane region Family:Magnesium transport protein CorA, transmembrane region 56 d1usha2 not modelled 8.5 17 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain 57 c2hy1A_ not modelled 8.3 33 PDB header:hydrolase Chain: A: PDB Molecule:rv0805; PDBTitle: crystal structure of rv0805 58 d2hy1a1 not modelled 8.3 33 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:GpdQ-like 59 c3bd0D_ not modelled 8.3 15 PDB header:peptide binding protein Chain: D: PDB Molecule:protein memo1; PDBTitle: crystal structure of memo, form ii 60 c2hbzA_ not modelled 8.3 16 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:caspase-1; PDBTitle: crystal structure of human caspase-1 (arg286->ala, glu390->ala) in2 complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-3 propionylamino]-4-oxo-pentanoic acid (z-vad-fmk) 61 d1yj5a1 not modelled 7.8 22 Fold:HAD-like Superfamily:HAD-like Family:phosphatase domain of polynucleotide kinase 62 d2hrca1 not modelled 7.7 25 Fold:Chelatase-like Superfamily:Chelatase Family:Ferrochelatase 63 d1a3xa3 not modelled 7.1 3 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:Pyruvate kinase, C-terminal domain 64 c3ib7A_ not modelled 7.0 33 PDB header:hydrolase Chain: A: PDB Molecule:icc protein; PDBTitle: crystal structure of full length rv0805 65 d1szpb1 not modelled 7.0 17 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 66 c3gnjD_ not modelled 7.0 10 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:thioredoxin domain protein; PDBTitle: the crystal structure of a thioredoxin-related protein from2 desulfitobacterium hafniense dcb 67 d1tfra2 not modelled 7.0 28 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 68 d1xfla_ not modelled 6.8 7 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 69 c2w6jG_ not modelled 6.6 24 PDB header:hydrolase Chain: G: PDB Molecule:atp synthase subunit gamma, mitochondrial; PDBTitle: low resolution structures of bovine mitochondrial f1-atpase2 during controlled dehydration: hydration state 5. 70 c2dfjA_ not modelled 6.3 21 PDB header:hydrolase Chain: A: PDB Molecule:diadenosinetetraphosphatase; PDBTitle: crystal structure of the diadenosine tetraphosphate2 hydrolase from shigella flexneri 2a 71 c1o7dA_ not modelled 6.1 14 PDB header:hydrolase Chain: A: PDB Molecule:lysosomal alpha-mannosidase; PDBTitle: the structure of the bovine lysosomal a-mannosidase2 suggests a novel mechanism for low ph activation 72 d1wdds_ not modelled 6.0 25 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 73 d2nxfa1 not modelled 6.0 21 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:ADPRibase-Mn-like 74 d1dt9a3 not modelled 5.8 13 Fold:N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Superfamily:N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Family:N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 75 c3mk7F_ not modelled 5.7 15 PDB header:oxidoreductase Chain: F: PDB Molecule:cytochrome c oxidase, cbb3-type, subunit p; PDBTitle: the structure of cbb3 cytochrome oxidase 76 d2fwha1 not modelled 5.6 18 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 77 d2g50a3 not modelled 5.6 14 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:Pyruvate kinase, C-terminal domain 78 c2z1aA_ not modelled 5.5 13 PDB header:hydrolase Chain: A: PDB Molecule:5'-nucleotidase; PDBTitle: crystal structure of 5'-nucleotidase precursor from thermus2 thermophilus hb8 79 d2jdig1 not modelled 5.5 22 Fold:Pyruvate kinase C-terminal domain-like Superfamily:ATP synthase (F1-ATPase), gamma subunit Family:ATP synthase (F1-ATPase), gamma subunit 80 d3bvua3 not modelled 5.4 7 Fold:7-stranded beta/alpha barrel Superfamily:Glycoside hydrolase/deacetylase Family:alpha-mannosidase 81 c2fp3A_ not modelled 5.4 14 PDB header:hydrolysis/apoptosis Chain: A: PDB Molecule:caspase nc; PDBTitle: crystal structure of the drosophila initiator caspase dronc 82 c1cp3B_ not modelled 5.1 15 PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:apopain; PDBTitle: crystal structure of the complex of apopain with the tetrapeptide2 inhibitor ace-dvad-fmc 83 d3c9fa2 not modelled 5.1 7 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0