Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	I	E	K	I	F	T	P	Q	D	D	A	F	Y	A	V	I	T	H	A	A	G	P	Q	G	A	L	P	L	T	P	Q	M	L	M	E	S	P	S	G	N	L	F	G	M	T	Q	N	A	G	M	G	W	D	A	N	K	L	T
Secondary structure
SS confidence
Disorder		?	?				?	?												?			?								?		?	?	?	?	?	?	?	?	?	?	?													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	K	E	V	L	I	I	G	T	Q	G	G	I	R	A	G	D	G	R	P	I	A	L	G	Y	H	T	G	H	W	E	I	G	M	Q	M	Q	A	A	A	K	E	I	T	R	N	G	G	I	P	F	A	A	F	V	S	D	P	C	D
Secondary structure
SS confidence
Disorder																?	?	?	?		?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	R	S	Q	G	T	H	G	M	F	D	S	L	P	Y	R	N	D	A	A	I	V	F	R	R	L	I	R	S	L	P	T	R	R	A	V	I	G	V	A	T	C	D	K	G	L	P	A	T	M	I	A	L	A	A	M	H	D	L	P
Secondary structure
SS confidence
Disorder					?	?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	I	L	V	P	G	G	A	T	L	P	P	T	V	G	E	D	A	G	K	V	Q	T	I	G	A	R	F	A	N	H	E	L	S	L	Q	E	A	A	E	L	G	C	R	A	C	A	S	P	G	G	G	C	Q	F	L	G	T	A	G
Secondary structure
SS confidence
Disorder														?	?	?	?														?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		T	S	Q	V	V	A	E	A	L	G	L	A	L	P	H	S	A	L	A	P	S	G	Q	A	V	W	L	E	I	A	R	Q	S	A	R	A	V	S	E	L	D	S	R	G	I	T	T	R	D	I	L	S	D	K	A	I	E	N	A	M
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		V	I	H	A	A	F	G	G	S	T	N	L	L	L	H	I	P	A	I	A	H	A	A	G	C	T	I	P	D	V	E	H	W	T	R	I	N	R	K	V	P	R	L	V	S	V	L	P	N	G	P	D	Y	H	P	T	V	R	A	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		L	A	G	G	V	P	E	V	M	L	H	L	R	D	L	G	L	L	H	L	D	A	M	T	V	T	G	Q	T	V	G	E	N	L	E	W	W	Q	A	S	E	R	R	A	R	F	R	Q	C	L	R	E	Q	D	G	V	E	P	D	D
Secondary structure
SS confidence
Disorder																																									?	?	?	?	?	?	?	?					?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		V	I	L	P	P	E	K	A	K	A	K	G	L	T	S	T	V	C	F	P	T	G	N	I	A	P	E	G	S	V	I	K	A	T	A	I	D	P	S	V	V	G	E	D	G	V	Y	H	H	T	G	R	V	R	V	F	V	S	E	A
Secondary structure
SS confidence
Disorder									?	?	?	?	?	?		?																					?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		Q	A	I	K	A	I	K	R	E	E	I	V	Q	G	D	I	M	V	V	I	G	G	G	P	S	G	T	G	M	E	E	T	Y	Q	L	T	S	A	L	K	H	I	S	W	G	K	T	V	S	L	I	T	D	A	R	F	S	G	V	S
Secondary structure
SS confidence
Disorder									?		?	?																?						?	?	?	?					?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		T	G	A	C	F	G	H	V	S	P	E	A	L	A	G	G	P	I	G	K	L	R	D	N	D	I	I	E	I	A	V	D	R	L	T	L	T	G	S	V	N	F	I	G	T	A	D	N	P	L	T	P	E	E	G	A	R	E	L	A
Secondary structure
SS confidence
Disorder																																											?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.
Sequence		R	R	Q	T	H	P	D	L	H	A	H	D	F	L	P	D	D	T	R	L	W	A	A	L	Q	S	V	S	G	G	T	W	K	G	C	I	Y	D	T	D	K	I	I	E	V	I	N	A	G	K	K	A	L	G	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?		?	?									?		?	?	?	?																					?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2gp4 chain A Region: 104 - 638 Aligned: 471 Modelled: 497 Confidence: 100.0% Identity: 28% PDB header:lyase Chain: A: PDB Molecule:6-phosphogluconate dehydratase; PDBTitle: structure of [fes]cluster-free apo form of 6-phosphogluconate2 dehydratase from shewanella oneidensis Phyre2 PDB 2gp4 chain A domain 2 Region: 88 - 435 Aligned: 308 Modelled: 326 Confidence: 100.0% Identity: 27% Fold: IlvD/EDD N-terminal domain-like Superfamily: IlvD/EDD N-terminal domain-like Family: lvD/EDD N-terminal domain-like Phyre2 PDB 2gp4 chain A domain 1 Region: 436 - 638 Aligned: 176 Modelled: 189 Confidence: 100.0% Identity: 26% Fold: The "swivelling" beta/beta/alpha domain Superfamily: LeuD/IlvD-like Family: IlvD/EDD C-terminal domain-like Phyre2 PDB 2pcn chain A Region: 452 - 535 Aligned: 77 Modelled: 84 Confidence: 79.3% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:s-adenosylmethionine:2-demethylmenaquinone PDBTitle: crystal structure of s-adenosylmethionine: 2-dimethylmenaquinone2 methyltransferase (gk_1813) from geobacillus kaustophilus hta426 Phyre2 PDB 2jv2 chain A Region: 561 - 580 Aligned: 20 Modelled: 20 Confidence: 69.3% Identity: 25% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein ph1500; PDBTitle: solution structure of the n-terminal domain of ph1500 Phyre2 PDB 1nxj chain A Region: 452 - 573 Aligned: 119 Modelled: 120 Confidence: 66.5% Identity: 15% Fold: The "swivelling" beta/beta/alpha domain Superfamily: RraA-like Family: RraA-like Phyre2 PDB 1nxj chain A Region: 452 - 573 Aligned: 119 Modelled: 120 Confidence: 66.5% Identity: 15% PDB header:unknown function Chain: A: PDB Molecule:probable s-adenosylmethionine:2- PDBTitle: structure of rv3853 from mycobacterium tuberculosis Phyre2 PDB 3c8o chain B Region: 437 - 573 Aligned: 120 Modelled: 122 Confidence: 64.9% Identity: 18% PDB header:hydrolase regulator Chain: B: PDB Molecule:regulator of ribonuclease activity a; PDBTitle: the crystal structure of rraa from pao1 Phyre2 PDB 1vi4 chain A Region: 437 - 572 Aligned: 120 Modelled: 120 Confidence: 62.5% Identity: 13% Fold: The "swivelling" beta/beta/alpha domain Superfamily: RraA-like Family: RraA-like Phyre2 PDB 1q5x chain A Region: 452 - 573 Aligned: 118 Modelled: 122 Confidence: 52.4% Identity: 15% Fold: The "swivelling" beta/beta/alpha domain Superfamily: RraA-like Family: RraA-like Phyre2 PDB 1agx chain A Region: 61 - 196 Aligned: 124 Modelled: 136 Confidence: 51.7% Identity: 15% Fold: Glutaminase/Asparaginase Superfamily: Glutaminase/Asparaginase Family: Glutaminase/Asparaginase Phyre2 PDB 1pl8 chain A domain 1 Region: 482 - 506 Aligned: 24 Modelled: 25 Confidence: 50.0% Identity: 21% Fold: GroES-like Superfamily: GroES-like Family: Alcohol dehydrogenase-like, N-terminal domain Phyre2 PDB 1wsa chain A Region: 61 - 212 Aligned: 131 Modelled: 144 Confidence: 45.6% Identity: 21% Fold: Glutaminase/Asparaginase Superfamily: Glutaminase/Asparaginase Family: Glutaminase/Asparaginase Phyre2 PDB 1y0p chain A domain 2 Region: 478 - 550 Aligned: 64 Modelled: 73 Confidence: 42.7% Identity: 23% Fold: FAD/NAD(P)-binding domain Superfamily: FAD/NAD(P)-binding domain Family: Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain Phyre2 PDB 2hi6 chain A domain 1 Region: 561 - 579 Aligned: 19 Modelled: 19 Confidence: 40.6% Identity: 11% Fold: The "swivelling" beta/beta/alpha domain Superfamily: LeuD/IlvD-like Family: AF0055-like Phyre2 PDB 1ydg chain A Region: 81 - 283 Aligned: 180 Modelled: 182 Confidence: 37.2% Identity: 13% Fold: Flavodoxin-like Superfamily: Flavoproteins Family: WrbA-like Phyre2 PDB 1fjc chain A Region: 474 - 508 Aligned: 35 Modelled: 35 Confidence: 35.2% Identity: 34% Fold: Ferredoxin-like Superfamily: RNA-binding domain, RBD Family: Canonical RBD Phyre2 PDB 1wl8 chain A domain 1 Region: 178 - 250 Aligned: 48 Modelled: 55 Confidence: 35.1% Identity: 23% Fold: Flavodoxin-like Superfamily: Class I glutamine amidotransferase-like Family: Class I glutamine amidotransferases (GAT) Phyre2 PDB 1r31 chain A domain 1 Region: 232 - 249 Aligned: 17 Modelled: 18 Confidence: 35.0% Identity: 35% Fold: Ferredoxin-like Superfamily: NAD-binding domain of HMG-CoA reductase Family: NAD-binding domain of HMG-CoA reductase Phyre2 PDB 1j33 chain A Region: 231 - 381 Aligned: 125 Modelled: 151 Confidence: 34.4% Identity: 19% Fold: Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Superfamily: Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Family: Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Phyre2 1 c2gp4A_ 2 d2gp4a2 3 d2gp4a1 4 c2pcnA_ 5 c2jv2A_ 6 d1nxja_ 7 c1nxjA_ 8 c3c8oB_ 9 d1vi4a_ 10 d1q5xa_ 11 d1agxa_ 12 d1pl8a1 13 d1wsaa_ 14 d1y0pa2 15 d2hi6a1 16 d1ydga_ 17 d1fjca_ 18 d1wl8a1 19 d1r31a1 20 d1j33a_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99