Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	L	L	A	S	L	R	D	W	L	K	A	Q	Q	L	D	A	V	L	L	S	S	R	Q	N	K	Q	P	H	L	G	I	S	T	G	S	G	Y	V	V	I	S	R	E	S	A	H	I	L	V	D	S	R	Y	Y	V	E	V	E
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	R	A	Q	G	Y	Q	L	H	L	L	D	A	T	N	T	L	T	T	I	V	N	Q	I	I	A	D	E	Q	L	Q	T	L	G	F	E	G	Q	Q	V	S	W	E	T	A	H	R	W	Q	S	E	L	N	A	K	L	V	S	A	T
Secondary structure
SS confidence
Disorder																																																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	D	V	L	R	Q	I	K	T	P	E	E	V	E	K	I	R	L	A	C	G	I	A	D	R	G	A	E	H	I	R	R	F	I	Q	A	G	M	S	E	R	E	I	A	A	E	L	E	W	F	M	R	Q	Q	G	A	E	K	A	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		F	D	T	I	V	A	S	G	W	R	G	A	L	P	H	G	K	A	S	D	K	I	V	A	A	G	E	F	V	T	L	D	F	G	A	L	Y	Q	G	Y	C	S	D	M	T	R	T	L	L	V	N	G	E	G	V	S	A	E	S	H
Secondary structure
SS confidence
Disorder																																																											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	L	F	N	V	Y	Q	I	V	L	Q	A	Q	L	A	A	I	S	A	I	R	P	G	V	R	C	Q	Q	V	D	D	A	A	R	R	V	I	T	E	A	G	Y	G	D	Y	F	G	H	N	T	G	H	A	I	G	I	E	V	H	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		D	P	R	F	S	P	R	D	T	T	T	L	Q	P	G	M	L	L	T	V	E	P	G	I	Y	L	P	G	Q	G	G	V	R	I	E	D	V	V	L	V	T	P	Q	G	A	E	V	L	Y	A	M	P	K	T	V	L	L	T	G	E
Secondary structure
SS confidence
Disorder																																																												?	?
Disorder confidence
		.
Sequence		A
Secondary structure
SS confidence
Disorder		?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3q6d chain A Region: 1 - 358 Aligned: 351 Modelled: 353 Confidence: 100.0% Identity: 44% PDB header:viral protein Chain: A: PDB Molecule:proline dipeptidase; PDBTitle: xaa-pro dipeptidase from bacillus anthracis. Phyre2 PDB 1wy2 chain B Region: 3 - 356 Aligned: 342 Modelled: 343 Confidence: 100.0% Identity: 39% PDB header:hydrolase Chain: B: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal structure of the prolidase from pyrococcus horikoshii ot3 Phyre2 PDB 2how chain B Region: 3 - 358 Aligned: 347 Modelled: 351 Confidence: 100.0% Identity: 32% PDB header:hydrolase Chain: B: PDB Molecule:356aa long hypothetical dipeptidase; PDBTitle: dipeptidase (ph0974) from pyrococcus horikoshii ot3 Phyre2 PDB 2zsg chain B Region: 9 - 358 Aligned: 343 Modelled: 350 Confidence: 100.0% Identity: 37% PDB header:hydrolase Chain: B: PDB Molecule:aminopeptidase p, putative; PDBTitle: crystal structure of x-pro aminopeptidase from thermotoga maritima2 msb8 Phyre2 PDB 1chm chain A Region: 3 - 355 Aligned: 348 Modelled: 348 Confidence: 100.0% Identity: 23% PDB header:creatinase Chain: A: PDB Molecule:creatine amidinohydrolase; PDBTitle: enzymatic mechanism of creatine amidinohydrolase as deduced2 from crystal structures Phyre2 PDB 3ctz chain A Region: 2 - 352 Aligned: 344 Modelled: 351 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro aminopeptidase 1; PDBTitle: structure of human cytosolic x-prolyl aminopeptidase Phyre2 PDB 1w7v chain D Region: 3 - 355 Aligned: 348 Modelled: 353 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: D: PDB Molecule:xaa-pro aminopeptidase; PDBTitle: znmg substituted aminopeptidase p from e. coli Phyre2 PDB 2okn chain B Region: 3 - 355 Aligned: 349 Modelled: 353 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: B: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal strcture of human prolidase Phyre2 PDB 3cb5 chain A Region: 3 - 355 Aligned: 347 Modelled: 353 Confidence: 100.0% Identity: 19% PDB header:transcription Chain: A: PDB Molecule:fact complex subunit spt16; PDBTitle: crystal structure of the s. pombe peptidase homology domain of fact2 complex subunit spt16 (form a) Phyre2 PDB 3ig4 chain E Region: 3 - 355 Aligned: 345 Modelled: 353 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: E: PDB Molecule:xaa-pro aminopeptidase; PDBTitle: structure of a putative aminopeptidase p from bacillus anthracis Phyre2 PDB 3l24 chain A Region: 2 - 353 Aligned: 345 Modelled: 352 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal structure of the nerve agent degrading2 organophosphate anhydrolase/prolidase in complex with3 inhibitors Phyre2 PDB 3bit chain A Region: 3 - 355 Aligned: 348 Modelled: 353 Confidence: 100.0% Identity: 16% PDB header:transcription Chain: A: PDB Molecule:fact complex subunit spt16; PDBTitle: crystal structure of yeast spt16 n-terminal domain Phyre2 PDB 1kp0 chain B Region: 3 - 355 Aligned: 326 Modelled: 353 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: B: PDB Molecule:creatine amidinohydrolase; PDBTitle: the crystal structure analysis of creatine amidinohydrolase2 from actinobacillus Phyre2 PDB 1pv9 chain A domain 2 Region: 128 - 353 Aligned: 221 Modelled: 226 Confidence: 100.0% Identity: 51% Fold: Creatinase/aminopeptidase Superfamily: Creatinase/aminopeptidase Family: Creatinase/aminopeptidase Phyre2 PDB 2g6p chain A Region: 97 - 354 Aligned: 252 Modelled: 258 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase 1; PDBTitle: crystal structure of truncated (delta 1-89) human methionine2 aminopeptidase type 1 in complex with pyridyl pyrimidine derivative Phyre2 PDB 2gz5 chain A Region: 97 - 354 Aligned: 252 Modelled: 258 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase 1; PDBTitle: human type 1 methionine aminopeptidase in complex with ovalicin at 1.12 ang Phyre2 PDB 3s6b chain A Region: 121 - 358 Aligned: 235 Modelled: 238 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure of methionine aminopeptidase 1b from plasmodium2 falciparum, pf10_0150 Phyre2 PDB 3mx6 chain A Region: 126 - 355 Aligned: 224 Modelled: 230 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure of methionine aminopeptidase from rickettsia2 prowazekii bound to methionine Phyre2 PDB 1chm chain A domain 2 Region: 126 - 355 Aligned: 225 Modelled: 225 Confidence: 100.0% Identity: 28% Fold: Creatinase/aminopeptidase Superfamily: Creatinase/aminopeptidase Family: Creatinase/aminopeptidase Phyre2 PDB 1yj3 chain A Region: 114 - 351 Aligned: 232 Modelled: 238 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure analysis of product bound methionine2 aminopeptidase type 1c from mycobacterium tuberculosis Phyre2 1 c3q6dA_ 2 c1wy2B_ 3 c2howB_ 4 c2zsgB_ 5 c1chmA_ 6 c3ctzA_ 7 c1w7vD_ 8 c2oknB_ 9 c3cb5A_ 10 c3ig4E_ 11 c3l24A_ 12 c3bitA_ 13 c1kp0B_ 14 d1pv9a2 15 c2g6pA_ 16 c2gz5A_ 17 c3s6bA_ 18 c3mx6A_ 19 d1chma2 20 c1yj3A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3q6dA_ 100.0 44 PDB header:viral protein Chain: A: PDB Molecule:proline dipeptidase; PDBTitle: xaa-pro dipeptidase from bacillus anthracis. 2 c1wy2B_ 100.0 39 PDB header:hydrolase Chain: B: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal structure of the prolidase from pyrococcus horikoshii ot3 3 c2howB_ 100.0 32 PDB header:hydrolase Chain: B: PDB Molecule:356aa long hypothetical dipeptidase; PDBTitle: dipeptidase (ph0974) from pyrococcus horikoshii ot3 4 c2zsgB_ 100.0 37 PDB header:hydrolase Chain: B: PDB Molecule:aminopeptidase p, putative; PDBTitle: crystal structure of x-pro aminopeptidase from thermotoga maritima2 msb8 5 c1chmA_ 100.0 23 PDB header:creatinase Chain: A: PDB Molecule:creatine amidinohydrolase; PDBTitle: enzymatic mechanism of creatine amidinohydrolase as deduced2 from crystal structures 6 c3ctzA_ 100.0 24 PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro aminopeptidase 1; PDBTitle: structure of human cytosolic x-prolyl aminopeptidase 7 c1w7vD_ 100.0 24 PDB header:hydrolase Chain: D: PDB Molecule:xaa-pro aminopeptidase; PDBTitle: znmg substituted aminopeptidase p from e. coli 8 c2oknB_ 100.0 30 PDB header:hydrolase Chain: B: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal strcture of human prolidase 9 c3cb5A_ 100.0 19 PDB header:transcription Chain: A: PDB Molecule:fact complex subunit spt16; PDBTitle: crystal structure of the s. pombe peptidase homology domain of fact2 complex subunit spt16 (form a) 10 c3ig4E_ 100.0 25 PDB header:hydrolase Chain: E: PDB Molecule:xaa-pro aminopeptidase; PDBTitle: structure of a putative aminopeptidase p from bacillus anthracis 11 c3l24A_ 100.0 24 PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal structure of the nerve agent degrading2 organophosphate anhydrolase/prolidase in complex with3 inhibitors 12 c3bitA_ 100.0 16 PDB header:transcription Chain: A: PDB Molecule:fact complex subunit spt16; PDBTitle: crystal structure of yeast spt16 n-terminal domain 13 c1kp0B_ 100.0 25 PDB header:hydrolase Chain: B: PDB Molecule:creatine amidinohydrolase; PDBTitle: the crystal structure analysis of creatine amidinohydrolase2 from actinobacillus 14 d1pv9a2 100.0 51 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 15 c2g6pA_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase 1; PDBTitle: crystal structure of truncated (delta 1-89) human methionine2 aminopeptidase type 1 in complex with pyridyl pyrimidine derivative 16 c2gz5A_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase 1; PDBTitle: human type 1 methionine aminopeptidase in complex with ovalicin at 1.12 ang 17 c3s6bA_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure of methionine aminopeptidase 1b from plasmodium2 falciparum, pf10_0150 18 c3mx6A_ 100.0 25 PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure of methionine aminopeptidase from rickettsia2 prowazekii bound to methionine 19 d1chma2 100.0 28 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 20 c1yj3A_ 100.0 25 PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure analysis of product bound methionine2 aminopeptidase type 1c from mycobacterium tuberculosis 21 d2gg2a1 not modelled 100.0 25 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 22 c3tavA_ not modelled 100.0 28 PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure of a methionine aminopeptidase from mycobacterium2 abscessus 23 d2v3za2 not modelled 100.0 33 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 24 d1o0xa_ not modelled 100.0 27 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 25 d1qxya_ not modelled 100.0 25 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 26 d1b6aa2 not modelled 100.0 18 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 27 c2v6cA_ not modelled 100.0 19 PDB header:transcription regulator Chain: A: PDB Molecule:proliferation-associated protein 2g4; PDBTitle: crystal structure of erbb3 binding protein 1 (ebp1) 28 d1xgsa2 not modelled 100.0 24 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 29 c2q8kA_ not modelled 100.0 20 PDB header:transcription Chain: A: PDB Molecule:proliferation-associated protein 2g4; PDBTitle: the crystal structure of ebp1 30 c1xgnB_ not modelled 100.0 26 PDB header:aminopeptidase Chain: B: PDB Molecule:methionine aminopeptidase; PDBTitle: methionine aminopeptidase from hyperthermophile pyrococcus2 furiosus 31 d1kp0a2 not modelled 100.0 27 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 32 c1b6aA_ not modelled 100.0 26 PDB header:angiogenesis inhibitor Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: human methionine aminopeptidase 2 complexed with tnp-470 33 c3fm3B_ not modelled 100.0 20 PDB header:hydrolase Chain: B: PDB Molecule:methionine aminopeptidase 2; PDBTitle: crystal structure of an encephalitozoon cuniculi methionine2 aminopeptidase type 2 34 c1yw7A_ not modelled 100.0 25 PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase 2; PDBTitle: h-metap2 complexed with a444148 35 c3pn9C_ not modelled 99.7 10 PDB header:hydrolase Chain: C: PDB Molecule:proline dipeptidase; PDBTitle: crystal structure of a proline dipeptidase from streptococcus2 pneumoniae tigr4 36 c3ovkD_ not modelled 99.7 24 PDB header:hydrolase Chain: D: PDB Molecule:aminopeptidase p, xaa-pro dipeptidase; PDBTitle: crystal structure of an xxa-pro aminopeptidase from streptococcus2 pyogenes 37 c3il0B_ not modelled 99.7 21 PDB header:hydrolase Chain: B: PDB Molecule:aminopeptidase p; xaa-pro aminopeptidase; PDBTitle: the crystal structure of the aminopeptidase p,xaa-pro aminopeptidase2 from streptococcus thermophilus 38 c3oooA_ not modelled 99.7 9 PDB header:hydrolase Chain: A: PDB Molecule:proline dipeptidase; PDBTitle: the structure of a proline dipeptidase from streptococcus agalactiae2 2603v 39 d1chma1 not modelled 99.6 15 Fold:Ribonuclease H-like motif Superfamily:Creatinase/prolidase N-terminal domain Family:Creatinase/prolidase N-terminal domain 40 c3i7mA_ not modelled 99.6 11 PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro dipeptidase; PDBTitle: n-terminal domain of xaa-pro dipeptidase from lactobacillus brevis. 41 c3o5vA_ not modelled 99.6 9 PDB header:hydrolase Chain: A: PDB Molecule:x-pro dipeptidase; PDBTitle: the crystal structure of the creatinase/prolidase n-terminal domain of2 an x-pro dipeptidase from streptococcus pyogenes to 1.85a 42 c3qocD_ not modelled 99.6 18 PDB header:hydrolase Chain: D: PDB Molecule:putative metallopeptidase; PDBTitle: crystal structure of n-terminal domain (creatinase/prolidase like2 domain) of putative metallopeptidase from corynebacterium diphtheriae 43 d1pv9a1 not modelled 99.5 19 Fold:Ribonuclease H-like motif Superfamily:Creatinase/prolidase N-terminal domain Family:Creatinase/prolidase N-terminal domain 44 d1kp0a1 not modelled 98.3 21 Fold:Ribonuclease H-like motif Superfamily:Creatinase/prolidase N-terminal domain Family:Creatinase/prolidase N-terminal domain 45 d2v3za1 not modelled 97.8 8 Fold:Ribonuclease H-like motif Superfamily:Creatinase/prolidase N-terminal domain Family:Creatinase/prolidase N-terminal domain 46 c2y0oA_ not modelled 53.5 13 PDB header:isomerase Chain: A: PDB Molecule:probable d-lyxose ketol-isomerase; PDBTitle: the structure of a d-lyxose isomerase from the sigmab2 regulon of bacillus subtilis 47 c3mpbA_ not modelled 41.9 24 PDB header:isomerase Chain: A: PDB Molecule:sugar isomerase; PDBTitle: z5688 from e. coli o157:h7 bound to fructose 48 d1rp1a2 not modelled 27.3 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Pancreatic lipase, N-terminal domain 49 c3prdA_ not modelled 26.7 27 PDB header:chaperone, isomerase Chain: A: PDB Molecule:fkbp-type peptidyl-prolyl cis-trans isomerase; PDBTitle: structural analysis of protein folding by the methanococcus jannaschii2 chaperone fkbp26 50 c2pplA_ not modelled 26.1 30 PDB header:hydrolase Chain: A: PDB Molecule:pancreatic lipase-related protein 1; PDBTitle: human pancreatic lipase-related protein 1 51 d1hpla2 not modelled 25.9 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Pancreatic lipase, N-terminal domain 52 d1l1pa_ not modelled 25.6 38 Fold:FKBP-like Superfamily:FKBP-like Family:FKBP immunophilin/proline isomerase 53 d1e4cp_ not modelled 25.5 25 Fold:AraD/HMP-PK domain-like Superfamily:AraD/HMP-PK domain-like Family:AraD-like aldolase/epimerase 54 d1etha2 not modelled 24.2 23 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Pancreatic lipase, N-terminal domain 55 c2c5qE_ not modelled 23.1 17 PDB header:structural genomics,unknown function Chain: E: PDB Molecule:rraa-like protein yer010c; PDBTitle: crystal structure of yeast yer010cp 56 d1lpbb2 not modelled 22.4 23 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Pancreatic lipase, N-terminal domain 57 c2pvsB_ not modelled 22.1 23 PDB header:hydrolase Chain: B: PDB Molecule:pancreatic lipase-related protein 2; PDBTitle: structure of human pancreatic lipase related protein 22 mutant n336q 58 d1gpla2 not modelled 21.8 23 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Pancreatic lipase, N-terminal domain 59 c1hplB_ not modelled 21.0 20 PDB header:hydrolase(carboxylic esterase) Chain: B: PDB Molecule:lipase; PDBTitle: horse pancreatic lipase. the crystal structure at 2.32 angstroms resolution 60 d1t11a3 not modelled 21.0 29 Fold:FKBP-like Superfamily:FKBP-like Family:FKBP immunophilin/proline isomerase 61 d1bu8a2 not modelled 20.8 27 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Pancreatic lipase, N-terminal domain 62 c1rp1A_ not modelled 20.4 20 PDB header:hydrolase Chain: A: PDB Molecule:pancreatic lipase related protein 1; PDBTitle: dog pancreatic lipase related protein 1 63 c1gplA_ not modelled 18.8 23 PDB header:serine esterase Chain: A: PDB Molecule:rp2 lipase; PDBTitle: rp2 lipase 64 c2opiB_ not modelled 15.5 22 PDB header:lyase Chain: B: PDB Molecule:l-fuculose-1-phosphate aldolase; PDBTitle: crystal structure of l-fuculose-1-phosphate aldolase from bacteroides2 thetaiotaomicron 65 c2gezE_ not modelled 15.1 12 PDB header:hydrolase Chain: E: PDB Molecule:l-asparaginase alpha subunit; PDBTitle: crystal structure of potassium-independent plant asparaginase 66 c1htrP_ not modelled 14.9 25 PDB header:aspartyl protease Chain: P: PDB Molecule:progastricsin (pro segment); PDBTitle: crystal and molecular structures of human progastricsin at 1.622 angstroms resolution 67 d1b25a2 not modelled 14.8 20 Fold:Aldehyde ferredoxin oxidoreductase, N-terminal domain Superfamily:Aldehyde ferredoxin oxidoreductase, N-terminal domain Family:Aldehyde ferredoxin oxidoreductase, N-terminal domain 68 c2kw0A_ not modelled 14.6 16 PDB header:oxidoreductase Chain: A: PDB Molecule:ccmh protein; PDBTitle: solution structure of n-terminal domain of ccmh from escherichia.coli 69 d1rm4a1 not modelled 14.3 14 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 70 d1aora2 not modelled 14.0 26 Fold:Aldehyde ferredoxin oxidoreductase, N-terminal domain Superfamily:Aldehyde ferredoxin oxidoreductase, N-terminal domain Family:Aldehyde ferredoxin oxidoreductase, N-terminal domain 71 c3a9lB_ not modelled 13.8 21 PDB header:hydrolase Chain: B: PDB Molecule:poly-gamma-glutamate hydrolase; PDBTitle: structure of bacteriophage poly-gamma-glutamate hydrolase 72 c2gacA_ not modelled 13.5 14 PDB header:hydrolase Chain: A: PDB Molecule:glycosylasparaginase; PDBTitle: t152c mutant glycosylasparaginase from flavobacterium2 meningosepticum 73 c1avfQ_ not modelled 12.7 25 PDB header:aspartyl protease Chain: Q: PDB Molecule:gastricsin; PDBTitle: activation intermediate 2 of human gastricsin from human2 stomach 74 c2zakB_ not modelled 12.5 16 PDB header:hydrolase Chain: B: PDB Molecule:l-asparaginase precursor; PDBTitle: orthorhombic crystal structure of precursor e. coli isoaspartyl2 peptidase/l-asparaginase (ecaiii) with active-site t179a mutation 75 c3ds8A_ not modelled 11.3 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lin2722 protein; PDBTitle: the crysatl structure of the gene lin2722 products from listeria2 innocua 76 c2a8lB_ not modelled 11.1 16 PDB header:hydrolase Chain: B: PDB Molecule:threonine aspartase 1; PDBTitle: crystal structure of human taspase1 (t234a mutant) 77 d1hq0a_ not modelled 10.9 14 Fold:CNF1/YfiH-like putative cysteine hydrolases Superfamily:CNF1/YfiH-like putative cysteine hydrolases Family:Type 1 cytotoxic necrotizing factor, catalytic domain 78 d1eaka2 not modelled 10.7 60 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 79 d1ex9a_ not modelled 10.6 21 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Bacterial lipase 80 d1bqqm_ not modelled 10.1 60 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 81 c3edhA_ not modelled 10.0 46 PDB header:hydrolase Chain: A: PDB Molecule:bone morphogenetic protein 1; PDBTitle: crystal structure of bone morphogenetic protein 1 protease2 domain in complex with partially bound dmso 82 d1lgya_ not modelled 10.0 22 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Fungal lipases 83 d3tgla_ not modelled 10.0 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Fungal lipases 84 d1tiba_ not modelled 9.9 26 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Fungal lipases 85 c2b76N_ not modelled 9.9 16 PDB header:oxidoreductase Chain: N: PDB Molecule:fumarate reductase iron-sulfur protein; PDBTitle: e. coli quinol fumarate reductase frda e49q mutation 86 d1tiaa_ not modelled 9.9 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Fungal lipases 87 c3lqbA_ not modelled 9.7 46 PDB header:hydrolase Chain: A: PDB Molecule:loc792177 protein; PDBTitle: crystal structure of the hatching enzyme zhe1 from the zebrafish danio2 rerio 88 c2hl7A_ not modelled 9.6 26 PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome c-type biogenesis protein ccmh; PDBTitle: crystal structure of the periplasmic domain of ccmh from pseudomonas2 aeruginosa 89 d2ovxa1 not modelled 9.5 50 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 90 c1slmA_ not modelled 9.5 40 PDB header:hydrolase Chain: A: PDB Molecule:stromelysin-1; PDBTitle: crystal structure of fibroblast stromelysin-1: the c-truncated human2 proenzyme 91 d1rm8a_ not modelled 9.5 60 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 92 d1hova_ not modelled 9.4 60 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 93 c3re1B_ not modelled 9.3 19 PDB header:lyase Chain: B: PDB Molecule:uroporphyrinogen-iii synthetase; PDBTitle: crystal structure of uroporphyrinogen iii synthase from pseudomonas2 syringae pv. tomato dc3000 94 c2kxxA_ not modelled 9.3 25 PDB header:protein binding Chain: A: PDB Molecule:small protein a; PDBTitle: nmr structure of escherichia coli bame, a lipoprotein component of the2 beta-barrel assembly machinery complex 95 c3nr7A_ not modelled 9.2 33 PDB header:dna binding protein Chain: A: PDB Molecule:dna-binding protein h-ns; PDBTitle: crystal structure of s. typhimurium h-ns 1-83 96 d1q3aa_ not modelled 9.2 40 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 97 c3o0dF_ not modelled 9.1 33 PDB header:hydrolase Chain: F: PDB Molecule:triacylglycerol lipase; PDBTitle: crystal structure of lip2 lipase from yarrowia lipolytica at 1.7 a2 resolution 98 d1w26a3 not modelled 9.0 37 Fold:FKBP-like Superfamily:FKBP-like Family:FKBP immunophilin/proline isomerase 99 d1cgla_ not modelled 9.0 40 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0