Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	K	A	T	E	Q	N	D	K	L	K	R	A	I	I	I	S	A	V	L	H	V	I	L	F	A	A	L	I	W	S	S	F	D	E	N	I	E	A	S	A	G	G	G	G	G	S	S	I	D	A	V	M	V	D	S	G	A	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?																									?	?	?	?	?	?	?	?	?	?	?	?	?	?	?						?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	E	Q	Y	K	R	M	Q	S	Q	E	S	S	A	K	R	S	D	E	Q	R	K	M	K	E	Q	Q	A	A	E	E	L	R	E	K	Q	A	A	E	Q	E	R	L	K	Q	L	E	K	E	R	L	A	A	Q	E	Q	K	K	Q	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	E	A	A	K	Q	A	E	L	K	Q	K	Q	A	E	E	A	A	A	K	A	A	A	D	A	K	A	K	A	E	A	D	A	K	A	A	E	E	A	A	K	K	A	A	A	D	A	K	K	K	A	E	A	E	A	A	K	A	A	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		E	A	Q	K	K	A	E	A	A	A	A	A	L	K	K	K	A	E	A	A	E	A	A	A	A	E	A	R	K	K	A	A	T	E	A	A	E	K	A	K	A	E	A	E	K	K	A	A	A	E	K	A	A	A	D	K	K	A	A	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		E	K	A	A	A	D	K	K	A	A	E	K	A	A	A	E	K	A	A	A	D	K	K	A	A	A	E	K	A	A	A	D	K	K	A	A	A	A	K	A	A	A	E	K	A	A	A	A	K	A	A	A	E	A	D	D	I	F	G	E
Secondary structure
SS confidence
Disorder																																																												?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		L	S	S	G	K	N	A	P	K	T	G	G	G	A	K	G	N	N	A	S	P	A	G	S	G	N	T	K	N	N	G	A	S	G	A	D	I	N	N	Y	A	G	Q	I	K	S	A	I	E	S	K	F	Y	D	A	S	S	Y	A	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																?	?		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		K	T	C	T	L	R	I	K	L	A	P	D	G	M	L	L	D	I	K	P	E	G	G	D	P	A	L	C	Q	A	A	L	A	A	A	K	L	A	K	I	P	K	P	P	S	Q	A	V	Y	E	V	F	K	N	A	P	L	D	F	K
Secondary structure
SS confidence
Disorder		?									?	?		?						?	?	?															?	?	?	?	?	?	?		?										?	?	?	?	?	?	?
Disorder confidence
		.
Sequence		P
Secondary structure
SS confidence
Disorder		?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1tol chain A Region: 328 - 421 Aligned: 94 Modelled: 94 Confidence: 100.0% Identity: 95% PDB header:viral protein Chain: A: PDB Molecule:protein (fusion protein consisting of minor coat PDBTitle: fusion of n-terminal domain of the minor coat protein from2 gene iii in phage m13, and c-terminal domain of e. coli3 protein-tola Phyre2 PDB 1tol chain A domain 2 Region: 333 - 421 Aligned: 89 Modelled: 89 Confidence: 99.9% Identity: 100% Fold: TolA/TonB C-terminal domain Superfamily: TolA/TonB C-terminal domain Family: TolA Phyre2 PDB 2x9a chain B Region: 333 - 421 Aligned: 89 Modelled: 89 Confidence: 99.9% Identity: 100% PDB header:viral protein Chain: B: PDB Molecule:membrane spanning protein, required for outer membrane PDBTitle: crystal structure of g3p from phage if1 in complex with its2 coreceptor, the c-terminal domain of tola Phyre2 PDB 1lr0 chain A Region: 313 - 421 Aligned: 109 Modelled: 109 Confidence: 99.8% Identity: 16% Fold: TolA/TonB C-terminal domain Superfamily: TolA/TonB C-terminal domain Family: TolA Phyre2 PDB 1ihr chain A Region: 357 - 421 Aligned: 64 Modelled: 65 Confidence: 97.7% Identity: 9% Fold: TolA/TonB C-terminal domain Superfamily: TolA/TonB C-terminal domain Family: TonB Phyre2 PDB 2grx chain C Region: 362 - 420 Aligned: 54 Modelled: 59 Confidence: 97.2% Identity: 15% PDB header:metal transport Chain: C: PDB Molecule:protein tonb; PDBTitle: crystal structure of tonb in complex with fhua, e. coli2 outer membrane receptor for ferrichrome Phyre2 PDB 1xx3 chain A Region: 362 - 405 Aligned: 44 Modelled: 44 Confidence: 97.2% Identity: 11% PDB header:transport protein Chain: A: PDB Molecule:tonb protein; PDBTitle: solution structure of escherichia coli tonb-ctd Phyre2 PDB 2gsk chain B domain 1 Region: 362 - 405 Aligned: 44 Modelled: 44 Confidence: 96.9% Identity: 9% Fold: TolA/TonB C-terminal domain Superfamily: TolA/TonB C-terminal domain Family: TonB Phyre2 PDB 2k9k chain A Region: 362 - 420 Aligned: 59 Modelled: 59 Confidence: 96.7% Identity: 20% PDB header:metal transport Chain: A: PDB Molecule:tonb2; PDBTitle: molecular characterization of the tonb2 protein from vibrio2 anguillarum Phyre2 PDB 1u07 chain A Region: 362 - 405 Aligned: 44 Modelled: 44 Confidence: 96.6% Identity: 9% Fold: TolA/TonB C-terminal domain Superfamily: TolA/TonB C-terminal domain Family: TonB Phyre2 PDB 2dzk chain A Region: 355 - 385 Aligned: 30 Modelled: 31 Confidence: 54.3% Identity: 23% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:ubx domain-containing protein 2; PDBTitle: structure of the ubx domain in mouse ubx domain-containing2 protein 2 Phyre2 PDB 1y4c chain A Region: 174 - 297 Aligned: 124 Modelled: 124 Confidence: 50.4% Identity: 17% PDB header:de novo protein Chain: A: PDB Molecule:maltose binding protein fused with designed PDBTitle: designed helical protein fusion mbp Phyre2 PDB 2kxj chain A Region: 362 - 385 Aligned: 23 Modelled: 24 Confidence: 47.2% Identity: 22% PDB header:protein binding Chain: A: PDB Molecule:ubx domain-containing protein 4; PDBTitle: solution structure of ubx domain of human ubxd2 protein Phyre2 PDB 2ba0 chain G domain 2 Region: 348 - 398 Aligned: 51 Modelled: 51 Confidence: 41.0% Identity: 16% Fold: Ribonuclease PH domain 2-like Superfamily: Ribonuclease PH domain 2-like Family: Ribonuclease PH domain 2-like Phyre2 PDB 1r4x chain A domain 2 Region: 363 - 395 Aligned: 32 Modelled: 33 Confidence: 38.4% Identity: 16% Fold: Subdomain of clathrin and coatomer appendage domain Superfamily: Subdomain of clathrin and coatomer appendage domain Family: Coatomer appendage domain Phyre2 PDB 2e7g chain A domain 1 Region: 337 - 400 Aligned: 64 Modelled: 64 Confidence: 35.4% Identity: 11% Fold: Alpha-lytic protease prodomain-like Superfamily: Ribosome-binding factor A, RbfA Family: Ribosome-binding factor A, RbfA Phyre2 PDB 2ytx chain A Region: 359 - 383 Aligned: 25 Modelled: 25 Confidence: 35.3% Identity: 36% PDB header:rna binding protein Chain: A: PDB Molecule:cold shock domain-containing protein e1; PDBTitle: solution structure of the second cold-shock domain of the human2 kiaa0885 protein (unr protein) Phyre2 PDB 2nn6 chain C domain 2 Region: 352 - 398 Aligned: 47 Modelled: 47 Confidence: 35.1% Identity: 19% Fold: Ribonuclease PH domain 2-like Superfamily: Ribonuclease PH domain 2-like Family: Ribonuclease PH domain 2-like Phyre2 PDB 2zfd chain B Region: 367 - 394 Aligned: 28 Modelled: 28 Confidence: 33.6% Identity: 11% PDB header:signaling protein/transferase Chain: B: PDB Molecule:putative uncharacterized protein t20l15_90; PDBTitle: the crystal structure of plant specific calcium binding protein atcbl22 in complex with the regulatory domain of atcipk14 Phyre2 PDB 1ybx chain A Region: 365 - 398 Aligned: 34 Modelled: 34 Confidence: 32.0% Identity: 24% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: conserved hypothetical protein cth-383 from clostridium thermocellum Phyre2 1 c1tolA_ 2 d1tola2 3 c2x9aB_ 4 d1lr0a_ 5 d1ihra_ 6 c2grxC_ 7 c1xx3A_ 8 d2gskb1 9 c2k9kA_ 10 d1u07a_ 11 c2dzkA_ 12 c1y4cA_ 13 c2kxjA_ 14 d2ba0g2 15 d1r4xa2 16 d2e7ga1 17 c2ytxA_ 18 d2nn6c2 19 c2zfdB_ 20 c1ybxA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1tolA_ 100.0 95 PDB header:viral protein Chain: A: PDB Molecule:protein (fusion protein consisting of minor coat PDBTitle: fusion of n-terminal domain of the minor coat protein from2 gene iii in phage m13, and c-terminal domain of e. coli3 protein-tola 2 d1tola2 99.9 100 Fold:TolA/TonB C-terminal domain Superfamily:TolA/TonB C-terminal domain Family:TolA 3 c2x9aB_ 99.9 100 PDB header:viral protein Chain: B: PDB Molecule:membrane spanning protein, required for outer membrane PDBTitle: crystal structure of g3p from phage if1 in complex with its2 coreceptor, the c-terminal domain of tola 4 d1lr0a_ 99.8 16 Fold:TolA/TonB C-terminal domain Superfamily:TolA/TonB C-terminal domain Family:TolA 5 d1ihra_ 97.7 9 Fold:TolA/TonB C-terminal domain Superfamily:TolA/TonB C-terminal domain Family:TonB 6 c2grxC_ 97.2 15 PDB header:metal transport Chain: C: PDB Molecule:protein tonb; PDBTitle: crystal structure of tonb in complex with fhua, e. coli2 outer membrane receptor for ferrichrome 7 c1xx3A_ 97.2 11 PDB header:transport protein Chain: A: PDB Molecule:tonb protein; PDBTitle: solution structure of escherichia coli tonb-ctd 8 d2gskb1 96.9 9 Fold:TolA/TonB C-terminal domain Superfamily:TolA/TonB C-terminal domain Family:TonB 9 c2k9kA_ 96.7 20 PDB header:metal transport Chain: A: PDB Molecule:tonb2; PDBTitle: molecular characterization of the tonb2 protein from vibrio2 anguillarum 10 d1u07a_ 96.6 9 Fold:TolA/TonB C-terminal domain Superfamily:TolA/TonB C-terminal domain Family:TonB 11 c2dzkA_ 54.3 23 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:ubx domain-containing protein 2; PDBTitle: structure of the ubx domain in mouse ubx domain-containing2 protein 2 12 c1y4cA_ 50.4 17 PDB header:de novo protein Chain: A: PDB Molecule:maltose binding protein fused with designed PDBTitle: designed helical protein fusion mbp 13 c2kxjA_ 47.2 22 PDB header:protein binding Chain: A: PDB Molecule:ubx domain-containing protein 4; PDBTitle: solution structure of ubx domain of human ubxd2 protein 14 d2ba0g2 41.0 16 Fold:Ribonuclease PH domain 2-like Superfamily:Ribonuclease PH domain 2-like Family:Ribonuclease PH domain 2-like 15 d1r4xa2 38.4 16 Fold:Subdomain of clathrin and coatomer appendage domain Superfamily:Subdomain of clathrin and coatomer appendage domain Family:Coatomer appendage domain 16 d2e7ga1 35.4 11 Fold:Alpha-lytic protease prodomain-like Superfamily:Ribosome-binding factor A, RbfA Family:Ribosome-binding factor A, RbfA 17 c2ytxA_ 35.3 36 PDB header:rna binding protein Chain: A: PDB Molecule:cold shock domain-containing protein e1; PDBTitle: solution structure of the second cold-shock domain of the human2 kiaa0885 protein (unr protein) 18 d2nn6c2 35.1 19 Fold:Ribonuclease PH domain 2-like Superfamily:Ribonuclease PH domain 2-like Family:Ribonuclease PH domain 2-like 19 c2zfdB_ 33.6 11 PDB header:signaling protein/transferase Chain: B: PDB Molecule:putative uncharacterized protein t20l15_90; PDBTitle: the crystal structure of plant specific calcium binding protein atcbl22 in complex with the regulatory domain of atcipk14 20 c1ybxA_ 32.0 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: conserved hypothetical protein cth-383 from clostridium thermocellum 21 d1wj4a_ not modelled 31.8 15 Fold:beta-Grasp (ubiquitin-like) Superfamily:Ubiquitin-like Family:UBX domain 22 c2kzfA_ not modelled 31.0 11 PDB header:ribosomal protein Chain: A: PDB Molecule:ribosome-binding factor a; PDBTitle: solution nmr structure of the thermotoga maritima protein tm0855 a2 putative ribosome binding factor a 23 c1r4xA_ not modelled 29.0 14 PDB header:protein transport Chain: A: PDB Molecule:coatomer gamma subunit; PDBTitle: crystal structure analys of the gamma-copi appendage domain 24 d2nn6e2 not modelled 28.3 10 Fold:Ribonuclease PH domain 2-like Superfamily:Ribonuclease PH domain 2-like Family:Ribonuclease PH domain 2-like 25 c2vbcA_ not modelled 27.8 11 PDB header:hydrolase Chain: A: PDB Molecule:dengue 4 ns3 full-length protein; PDBTitle: crystal structure of the ns3 protease-helicase from dengue2 virus 26 c1pzdA_ not modelled 25.4 13 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:coatomer gamma subunit; PDBTitle: structural identification of a conserved appendage domain2 in the carboxyl-terminus of the copi gamma-subunit. 27 c3mfbA_ not modelled 21.8 33 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the s-type pyocin domain of eca16692 protein from erwinia carotovora, northeast structural3 genomics consortium target ewr82c 28 c2dnrA_ not modelled 20.0 20 PDB header:rna binding protein Chain: A: PDB Molecule:synaptojanin-1; PDBTitle: solution structure of rna binding domain in synaptojanin 1 29 c2zv4O_ not modelled 19.7 10 PDB header:structural protein Chain: O: PDB Molecule:major vault protein; PDBTitle: the structure of rat liver vault at 3.5 angstrom resolution 30 c3htyC_ not modelled 19.2 15 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:hypothetical protein bt_0869; PDBTitle: crystal structure of hypothetical protein bt_0869 from bacteroides2 thetaiotaomicron vpi-5482 (np_809782.1) at 1.95 a resolution 31 c3mlpE_ not modelled 18.8 11 PDB header:transcription/dna Chain: E: PDB Molecule:transcription factor coe1; PDBTitle: early b-cell factor 1 (ebf1) bound to dna 32 c1dxzA_ not modelled 18.6 26 PDB header:transmembrane protein Chain: A: PDB Molecule:acetylcholine receptor protein, alpha chain; PDBTitle: m2 transmembrane segment of alpha-subunit of nicotinic2 acetylcholine receptor from torpedo californica, nmr, 203 structures 33 d1jbia_ not modelled 18.4 12 Fold:LCCL domain Superfamily:LCCL domain Family:LCCL domain 34 c2i1jA_ not modelled 17.4 17 PDB header:cell adhesion, membrane protein Chain: A: PDB Molecule:moesin; PDBTitle: moesin from spodoptera frugiperda at 2.1 angstroms resolution 35 d2dyja1 not modelled 16.5 19 Fold:Alpha-lytic protease prodomain-like Superfamily:Ribosome-binding factor A, RbfA Family:Ribosome-binding factor A, RbfA 36 c3ol0C_ not modelled 16.3 17 PDB header:de novo protein Chain: C: PDB Molecule:de novo designed monomer trefoil-fold sub-domain which PDBTitle: crystal structure of monofoil-4p homo-trimer: de novo designed monomer2 trefoil-fold sub-domain which forms homo-trimer assembly 37 d2nn6a2 not modelled 15.4 25 Fold:Ribonuclease PH domain 2-like Superfamily:Ribonuclease PH domain 2-like Family:Ribonuclease PH domain 2-like 38 c2kncB_ not modelled 15.1 11 PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-3; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex 39 d2cjoa_ not modelled 15.0 24 Fold:beta-Grasp (ubiquitin-like) Superfamily:2Fe-2S ferredoxin-like Family:2Fe-2S ferredoxin-related 40 d1wg1a_ not modelled 14.0 33 Fold:Ferredoxin-like Superfamily:RNA-binding domain, RBD Family:Canonical RBD 41 d1kkga_ not modelled 14.0 12 Fold:Alpha-lytic protease prodomain-like Superfamily:Ribosome-binding factor A, RbfA Family:Ribosome-binding factor A, RbfA 42 d1j8ba_ not modelled 13.4 10 Fold:YbaB-like Superfamily:YbaB-like Family:YbaB-like 43 d2je6a2 not modelled 12.8 20 Fold:Ribonuclease PH domain 2-like Superfamily:Ribonuclease PH domain 2-like Family:Ribonuclease PH domain 2-like 44 d1s48a_ not modelled 11.7 22 Fold:DNA/RNA polymerases Superfamily:DNA/RNA polymerases Family:RNA-dependent RNA-polymerase 45 c2rmzA_ not modelled 11.4 11 PDB header:cell adhesion Chain: A: PDB Molecule:integrin beta-3; PDBTitle: bicelle-embedded integrin beta3 transmembrane segment 46 d1kyfa2 not modelled 11.3 12 Fold:Subdomain of clathrin and coatomer appendage domain Superfamily:Subdomain of clathrin and coatomer appendage domain Family:Clathrin adaptor appendage, alpha and beta chain-specific domain 47 c3pn1A_ not modelled 11.2 20 PDB header:ligase/ligase inhibitor Chain: A: PDB Molecule:dna ligase; PDBTitle: novel bacterial nad+-dependent dna ligase inhibitors with broad2 spectrum potency and antibacterial efficacy in vivo 48 d2ux9a1 not modelled 11.1 23 Fold:Dodecin subunit-like Superfamily:Dodecin-like Family:Dodecin-like 49 c1sfeA_ not modelled 10.9 21 PDB header:dna-binding protein Chain: A: PDB Molecule:ada o6-methylguanine-dna methyltransferase; PDBTitle: ada o6-methylguanine-dna methyltransferase from escherichia coli 50 c1x65A_ not modelled 10.7 22 PDB header:rna binding protein Chain: A: PDB Molecule:unr protein; PDBTitle: solution structure of the third cold-shock domain of the human2 kiaa0885 protein (unr protein) 51 d2k8ea1 not modelled 10.4 14 Fold:YegP-like Superfamily:YegP-like Family:YegP-like 52 d1x6oa2 not modelled 10.2 27 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 53 d1nkza_ not modelled 9.7 15 Fold:Light-harvesting complex subunits Superfamily:Light-harvesting complex subunits Family:Light-harvesting complex subunits 54 c3ecyA_ not modelled 9.6 19 PDB header:hydrolase Chain: A: PDB Molecule:cg4584-pa, isoform a (bcdna.ld08534); PDBTitle: crystal structural analysis of drosophila melanogaster dutpase 55 d1sfea1 not modelled 9.6 21 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Methylated DNA-protein cysteine methyltransferase, C-terminal domain Family:Methylated DNA-protein cysteine methyltransferase, C-terminal domain 56 d2cr5a1 not modelled 9.5 20 Fold:beta-Grasp (ubiquitin-like) Superfamily:Ubiquitin-like Family:UBX domain 57 d1tl2a_ not modelled 9.5 14 Fold:5-bladed beta-propeller Superfamily:Tachylectin-2 Family:Tachylectin-2 58 c3ajbB_ not modelled 9.1 42 PDB header:protein transport Chain: B: PDB Molecule:peroxisomal biogenesis factor 19; PDBTitle: crystal structure of human pex3p in complex with n-terminal pex19p2 peptide 59 d1h8ca_ not modelled 9.0 27 Fold:beta-Grasp (ubiquitin-like) Superfamily:Ubiquitin-like Family:UBX domain 60 c1cu1B_ not modelled 9.0 28 PDB header:hydrolase Chain: B: PDB Molecule:protein (protease/helicase ns3); PDBTitle: crystal structure of an enzyme complex from hepatitis c2 virus 61 d1pa4a_ not modelled 9.0 10 Fold:Alpha-lytic protease prodomain-like Superfamily:Ribosome-binding factor A, RbfA Family:Ribosome-binding factor A, RbfA 62 c1ky6A_ not modelled 8.9 12 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:alpha-adaptin c; PDBTitle: ap-2 clathrin adaptor alpha-appendage in complex with epsin2 dpw peptide 63 d1puga_ not modelled 8.9 3 Fold:YbaB-like Superfamily:YbaB-like Family:YbaB-like 64 d1v9pa3 not modelled 8.8 15 Fold:ATP-grasp Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain Family:Adenylation domain of NAD+-dependent DNA ligase 65 d1ccwb_ not modelled 8.7 18 Fold:TIM beta/alpha-barrel Superfamily:Cobalamin (vitamin B12)-dependent enzymes Family:Glutamate mutase, large subunit 66 c3onrI_ not modelled 8.7 20 PDB header:metal binding protein Chain: I: PDB Molecule:protein transport protein sece2; PDBTitle: crystal structure of the calcium chelating immunodominant antigen,2 calcium dodecin (rv0379),from mycobacterium tuberculosis with a novel3 calcium-binding site 67 d1n1ba1 not modelled 8.6 23 Fold:alpha/alpha toroid Superfamily:Terpenoid cyclases/Protein prenyltransferases Family:Terpenoid cyclase N-terminal domain 68 c2zsjB_ not modelled 8.6 10 PDB header:lyase Chain: B: PDB Molecule:threonine synthase; PDBTitle: crystal structure of threonine synthase from aquifex aeolicus vf5 69 d1i42a_ not modelled 8.5 23 Fold:beta-Grasp (ubiquitin-like) Superfamily:Ubiquitin-like Family:UBX domain 70 c2k59B_ not modelled 8.5 33 PDB header:transport protein Chain: B: PDB Molecule:neuronal acetylcholine receptor subunit beta-2; PDBTitle: nmr structures of the second transmembrane domain of the2 neuronal acetylcholine receptor beta 2 subunit 71 d3bzka5 not modelled 8.5 21 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Tex RuvX-like domain-like 72 d1ta8a_ not modelled 8.3 22 Fold:ATP-grasp Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain Family:Adenylation domain of NAD+-dependent DNA ligase 73 c3p2oB_ not modelled 8.3 11 PDB header:oxidoreductase, hydrolase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni 74 c2jpxA_ not modelled 8.2 14 PDB header:viral protein Chain: A: PDB Molecule:vpu protein; PDBTitle: a18h vpu tm structure in lipid bilayers 75 c2l7qA_ not modelled 8.2 27 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved protein found in conjugate transposon; PDBTitle: solution nmr structure of conjugate transposon protein bvu_1572(27-2 141) from bacteroides vulgatus, northeast structural genomics3 consortium target bvr155 76 c1zbtA_ not modelled 8.0 16 PDB header:translation Chain: A: PDB Molecule:peptide chain release factor 1; PDBTitle: crystal structure of peptide chain release factor 1 (rf-1) (smu.1085)2 from streptococcus mutans at 2.34 a resolution 77 c1s1hJ_ not modelled 8.0 13 PDB header:ribosome Chain: J: PDB Molecule:40s ribosomal protein s20; PDBTitle: structure of the ribosomal 80s-eef2-sordarin complex from2 yeast obtained by docking atomic models for rna and protein3 components into a 11.7 a cryo-em map. this file, 1s1h,4 contains 40s subunit. the 60s ribosomal subunit is in file5 1s1i. 78 c2kncA_ not modelled 8.0 10 PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex 79 d1ijda_ not modelled 7.9 15 Fold:Light-harvesting complex subunits Superfamily:Light-harvesting complex subunits Family:Light-harvesting complex subunits 80 c2ihr1_ not modelled 7.9 12 PDB header:translation Chain: 1: PDB Molecule:peptide chain release factor 2; PDBTitle: rf2 of thermus thermophilus 81 d1j3wa_ not modelled 7.9 22 Fold:Profilin-like Superfamily:Roadblock/LC7 domain Family:Roadblock/LC7 domain 82 c3p2oA_ not modelled 7.8 11 PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni 83 c3muxB_ not modelled 7.6 21 PDB header:lyase Chain: B: PDB Molecule:putative 4-hydroxy-2-oxoglutarate aldolase; PDBTitle: the crystal structure of a putative 4-hydroxy-2-oxoglutarate aldolase2 from bacillus anthracis to 1.45a 84 d1oysa1 not modelled 7.6 15 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Ribonuclease PH domain 1-like 85 c2l3bA_ not modelled 7.5 27 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved protein found in conjugate transposon; PDBTitle: solution nmr structure of the bt_0084 lipoprotein from bacteroides2 thetaiotaomicron, northeast structural genomics consortium target3 btr376 86 c3oqtP_ not modelled 7.4 16 PDB header:flavoprotein Chain: P: PDB Molecule:rv1498a protein; PDBTitle: crystal structure of rv1498a protein from mycobacterium tuberculosis 87 c2y69R_ not modelled 7.3 33 PDB header:electron transport Chain: R: PDB Molecule:cytochrome c oxidase subunit 5a; PDBTitle: bovine heart cytochrome c oxidase re-refined with molecular2 oxygen 88 d1v54e_ not modelled 7.3 33 Fold:alpha-alpha superhelix Superfamily:Cytochrome c oxidase subunit E Family:Cytochrome c oxidase subunit E 89 c1a4iB_ not modelled 7.1 17 PDB header:oxidoreductase Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase / PDBTitle: human tetrahydrofolate dehydrogenase / cyclohydrolase 90 d1vk8a_ not modelled 7.1 18 Fold:Ferredoxin-like Superfamily:MTH1187/YkoF-like Family:MTH1187-like 91 d1dxwa_ not modelled 7.1 31 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Viral proteases 92 d1b04a_ not modelled 7.1 15 Fold:ATP-grasp Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain Family:Adenylation domain of NAD+-dependent DNA ligase 93 c1a11A_ not modelled 7.0 30 PDB header:acetylcholine receptor Chain: A: PDB Molecule:acetylcholine receptor m2; PDBTitle: nmr structure of membrane spanning segment 2 of the2 acetylcholine receptor in dpc micelles, 10 structures 94 c1yq3C_ not modelled 7.0 29 PDB header:oxidoreductase Chain: C: PDB Molecule:succinate dehydrogenase cytochrome b, large subunit; PDBTitle: avian respiratory complex ii with oxaloacetate and ubiquinone 95 c1eq8B_ not modelled 7.0 30 PDB header:signaling protein Chain: B: PDB Molecule:acetylcholine receptor protein; PDBTitle: three-dimensional structure of the pentameric helical2 bundle of the acetylcholine receptor m2 transmembrane3 segment 96 c1eq8D_ not modelled 7.0 30 PDB header:signaling protein Chain: D: PDB Molecule:acetylcholine receptor protein; PDBTitle: three-dimensional structure of the pentameric helical2 bundle of the acetylcholine receptor m2 transmembrane3 segment 97 c1eq8C_ not modelled 7.0 30 PDB header:signaling protein Chain: C: PDB Molecule:acetylcholine receptor protein; PDBTitle: three-dimensional structure of the pentameric helical2 bundle of the acetylcholine receptor m2 transmembrane3 segment 98 c1eq8E_ not modelled 7.0 30 PDB header:signaling protein Chain: E: PDB Molecule:acetylcholine receptor protein; PDBTitle: three-dimensional structure of the pentameric helical2 bundle of the acetylcholine receptor m2 transmembrane3 segment 99 c1eq8A_ not modelled 7.0 30 PDB header:signaling protein Chain: A: PDB Molecule:acetylcholine receptor protein; PDBTitle: three-dimensional structure of the pentameric helical2 bundle of the acetylcholine receptor m2 transmembrane3 segment

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0