Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	D	K	I	I	H	L	T	D	D	S	F	D	T	D	V	L	K	A	D	G	A	I	L	V	D	F	W	A	E	W	C	G	P	C	K	M	I	A	P	I	L	D	E	I	A	D	E	Y	Q	G	K	L	T	V	A	K	L	N
Secondary structure
SS confidence
Disorder		?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.
Sequence		I	D	Q	N	P	G	T	A	P	K	Y	G	I	R	G	I	P	T	L	L	L	F	K	N	G	E	V	A	A	T	K	V	G	A	L	S	K	G	Q	L	K	E	F	L	D	A	N	L	A
Secondary structure
SS confidence
Disorder												?																																					?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2trx chain A Region: 2 - 109 Aligned: 108 Modelled: 108 Confidence: 100.0% Identity: 100% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Thioltransferase Phyre2 PDB 3dxb chain E Region: 4 - 109 Aligned: 106 Modelled: 106 Confidence: 100.0% Identity: 100% PDB header:splicing, transcription Chain: E: PDB Molecule:thioredoxin n-terminally fused to puf60(uhm); PDBTitle: structure of the uhm domain of puf60 fused to thioredoxin Phyre2 PDB 2i4a chain A Region: 2 - 107 Aligned: 106 Modelled: 106 Confidence: 99.9% Identity: 58% PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of thioredoxin from the acidophile2 acetobacter aceti Phyre2 PDB 1thx chain A Region: 2 - 109 Aligned: 108 Modelled: 108 Confidence: 99.9% Identity: 43% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Thioltransferase Phyre2 PDB 1t00 chain A Region: 1 - 109 Aligned: 109 Modelled: 109 Confidence: 99.9% Identity: 55% PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: the structure of thioredoxin from s. coelicolor Phyre2 PDB 3p2a chain B Region: 2 - 109 Aligned: 107 Modelled: 108 Confidence: 99.9% Identity: 36% PDB header:oxidoreductase Chain: B: PDB Molecule:putative thioredoxin-like protein; PDBTitle: crystal structure of thioredoxin 2 from yersinia pestis Phyre2 PDB 2ppt chain A Region: 2 - 108 Aligned: 106 Modelled: 107 Confidence: 99.9% Identity: 32% PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin-2; PDBTitle: crystal structure of thioredoxin-2 Phyre2 PDB 3p2a chain A Region: 2 - 109 Aligned: 107 Modelled: 108 Confidence: 99.9% Identity: 36% PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin-like protein; PDBTitle: crystal structure of thioredoxin 2 from yersinia pestis Phyre2 PDB 3hz4 chain A Region: 2 - 109 Aligned: 108 Modelled: 105 Confidence: 99.9% Identity: 31% PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of thioredoxin from methanosarcina mazei Phyre2 PDB 1dby chain A Region: 4 - 109 Aligned: 106 Modelled: 106 Confidence: 99.9% Identity: 45% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Thioltransferase Phyre2 PDB 1oaz chain A Region: 2 - 109 Aligned: 108 Modelled: 108 Confidence: 99.9% Identity: 83% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Thioltransferase Phyre2 PDB 2voc chain A Region: 5 - 109 Aligned: 103 Modelled: 105 Confidence: 99.9% Identity: 48% PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: thioredoxin a active site mutants form mixed disulfide2 dimers that resemble enzyme-substrate reaction3 intermediate Phyre2 PDB 2i1u chain A Region: 5 - 108 Aligned: 104 Modelled: 104 Confidence: 99.9% Identity: 52% PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: mycobacterium tuberculosis thioredoxin c Phyre2 PDB 3gnj chain D Region: 2 - 108 Aligned: 107 Modelled: 105 Confidence: 99.9% Identity: 20% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:thioredoxin domain protein; PDBTitle: the crystal structure of a thioredoxin-related protein from2 desulfitobacterium hafniense dcb Phyre2 PDB 1fb6 chain A Region: 5 - 108 Aligned: 104 Modelled: 104 Confidence: 99.9% Identity: 48% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Thioltransferase Phyre2 PDB 1w89 chain E Region: 3 - 108 Aligned: 106 Modelled: 106 Confidence: 99.9% Identity: 33% PDB header:electron transport Chain: E: PDB Molecule:thioredoxin; PDBTitle: structure of the reduced form of human thioredoxin 2 Phyre2 PDB 3qdn chain A Region: 2 - 108 Aligned: 107 Modelled: 107 Confidence: 99.9% Identity: 27% PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin protein; PDBTitle: putative thioredoxin protein from salmonella typhimurium Phyre2 PDB 2o7k chain A Region: 5 - 108 Aligned: 102 Modelled: 104 Confidence: 99.9% Identity: 52% PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: s. aureus thioredoxin Phyre2 PDB 3tco chain A Region: 3 - 108 Aligned: 105 Modelled: 106 Confidence: 99.9% Identity: 38% PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin (trxa-1); PDBTitle: crystallographic and spectroscopic characterization of sulfolobus2 solfataricus trxa1 provide insights into the determinants of3 thioredoxin fold stability Phyre2 PDB 3f8u chain A Region: 4 - 109 Aligned: 106 Modelled: 106 Confidence: 99.9% Identity: 33% PDB header:immune system/isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a3erp57; PDBTitle: tapasin/erp57 heterodimer Phyre2 1 d2trxa_ 2 c3dxbE_ 3 c2i4aA_ 4 d1thxa_ 5 c1t00A_ 6 c3p2aB_ 7 c2pptA_ 8 c3p2aA_ 9 c3hz4A_ 10 d1dbya_ 11 d1oaza_ 12 c2vocA_ 13 c2i1uA_ 14 c3gnjD_ 15 d1fb6a_ 16 c1w89E_ 17 c3qdnA_ 18 c2o7kA_ 19 c3tcoA_ 20 c3f8uA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2trxa_ 100.0 100 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 2 c3dxbE_ 100.0 100 PDB header:splicing, transcription Chain: E: PDB Molecule:thioredoxin n-terminally fused to puf60(uhm); PDBTitle: structure of the uhm domain of puf60 fused to thioredoxin 3 c2i4aA_ 99.9 58 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of thioredoxin from the acidophile2 acetobacter aceti 4 d1thxa_ 99.9 43 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 5 c1t00A_ 99.9 55 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: the structure of thioredoxin from s. coelicolor 6 c3p2aB_ 99.9 36 PDB header:oxidoreductase Chain: B: PDB Molecule:putative thioredoxin-like protein; PDBTitle: crystal structure of thioredoxin 2 from yersinia pestis 7 c2pptA_ 99.9 32 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin-2; PDBTitle: crystal structure of thioredoxin-2 8 c3p2aA_ 99.9 36 PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin-like protein; PDBTitle: crystal structure of thioredoxin 2 from yersinia pestis 9 c3hz4A_ 99.9 31 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of thioredoxin from methanosarcina mazei 10 d1dbya_ 99.9 45 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 11 d1oaza_ 99.9 83 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 12 c2vocA_ 99.9 48 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: thioredoxin a active site mutants form mixed disulfide2 dimers that resemble enzyme-substrate reaction3 intermediate 13 c2i1uA_ 99.9 52 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: mycobacterium tuberculosis thioredoxin c 14 c3gnjD_ 99.9 20 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:thioredoxin domain protein; PDBTitle: the crystal structure of a thioredoxin-related protein from2 desulfitobacterium hafniense dcb 15 d1fb6a_ 99.9 48 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 16 c1w89E_ 99.9 33 PDB header:electron transport Chain: E: PDB Molecule:thioredoxin; PDBTitle: structure of the reduced form of human thioredoxin 2 17 c3qdnA_ 99.9 27 PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin protein; PDBTitle: putative thioredoxin protein from salmonella typhimurium 18 c2o7kA_ 99.9 52 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: s. aureus thioredoxin 19 c3tcoA_ 99.9 38 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin (trxa-1); PDBTitle: crystallographic and spectroscopic characterization of sulfolobus2 solfataricus trxa1 provide insights into the determinants of3 thioredoxin fold stability 20 c3f8uA_ 99.9 33 PDB header:immune system/isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a3erp57; PDBTitle: tapasin/erp57 heterodimer 21 d1f9ma_ not modelled 99.9 30 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 22 c3ed3A_ not modelled 99.9 26 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase mpd1; PDBTitle: crystal structure of the yeast dithiol/disulfide2 oxidoreductase mpd1p 23 c2albA_ not modelled 99.9 34 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a3; PDBTitle: nmr structure of the n-terminal domain a of the2 glycoprotein chaperone erp57 24 c2e0qA_ not modelled 99.9 39 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of k53e thioredoxin from sulfolobus2 tokodaii strain7 25 c1x5dA_ not modelled 99.9 35 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a6; PDBTitle: the solution structure of the second thioredoxin-like2 domain of human protein disulfide-isomerase a6 26 c2yzuA_ not modelled 99.9 51 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of oxidized thioredoxin from thermus thermophilus2 hb8 27 c2r2jA_ not modelled 99.9 29 PDB header:chaperone Chain: A: PDB Molecule:thioredoxin domain-containing protein 4; PDBTitle: crystal structure of human erp44 28 c3hypB_ not modelled 99.9 44 PDB header:electron transport Chain: B: PDB Molecule:thioredoxin; PDBTitle: crystal structure of bacteroides fragilis trxp_s105g mutant 29 c3apoA_ not modelled 99.9 26 PDB header:oxidoreductase Chain: A: PDB Molecule:dnaj homolog subfamily c member 10; PDBTitle: crystal structure of full-length erdj5 30 c2l5lA_ not modelled 99.9 42 PDB header:transport protein Chain: A: PDB Molecule:thioredoxin; PDBTitle: solution structure of thioredoxin from bacteroides vulgatus 31 c2b5eA_ not modelled 99.9 27 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase; PDBTitle: crystal structure of yeast protein disulfide isomerase 32 c2dmlA_ not modelled 99.9 28 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a6; PDBTitle: the solution structure of the first thioredoxin domain of2 mouse protein disulfide-isomerase a6 33 c3apsA_ not modelled 99.9 27 PDB header:oxidoreductase Chain: A: PDB Molecule:dnaj homolog subfamily c member 10; PDBTitle: crystal structure of trx4 domain of erdj5 34 d1ep7a_ not modelled 99.9 35 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 35 c2vafA_ not modelled 99.9 17 PDB header:metal-binding protein Chain: A: PDB Molecule:calsequestrin-2; PDBTitle: crystal structure of human cardiac calsequestrin 36 c1a8yA_ not modelled 99.9 18 PDB header:calcium-binding protein Chain: A: PDB Molecule:calsequestrin; PDBTitle: crystal structure of calsequestrin from rabbit skeletal muscle2 sarcoplasmic reticulum at 2.4 a resolution 37 c1sjiA_ not modelled 99.9 18 PDB header:metal binding protein Chain: A: PDB Molecule:calsequestrin, cardiac muscle isoform; PDBTitle: comparing skeletal and cardiac calsequestrin structures and2 their calcium binding: a proposed mechanism for coupled3 calcium binding and protein polymerization 38 d1xfla_ not modelled 99.9 29 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 39 d1xwaa_ not modelled 99.9 29 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 40 c2l6dA_ not modelled 99.9 20 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: solution structure of desulfothioredoxin from desulfovibrio vulgaris2 hildenborough in its reduced form 41 d1nw2a_ not modelled 99.9 49 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 42 c2dizA_ not modelled 99.9 30 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin domain-containing protein 5; PDBTitle: the solution structure of the third thioredoxin domain of2 human thioredoxin domain-containing protein 5 43 c2j23A_ not modelled 99.9 34 PDB header:immune protein Chain: A: PDB Molecule:thioredoxin; PDBTitle: cross-reactivity and crystal structure of malassezia2 sympodialis thioredoxin (mala s 13), a member of a new pan-3 allergen family 44 c2wz9A_ not modelled 99.9 26 PDB header:protein binding Chain: A: PDB Molecule:glutaredoxin-3; PDBTitle: crystal structure of the thioredoxin domain of human txnl2 45 d1gh2a_ not modelled 99.9 25 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 46 c2vlvA_ not modelled 99.9 27 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin h isoform 2.; PDBTitle: crystal structure of barley thioredoxin h isoform 2 in2 partially radiation-reduced state 47 c1x5cA_ not modelled 99.9 24 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase; PDBTitle: the solution structure of the second thioredoxin-like2 domain of human protein disulfide-isomerase 48 d1m7ta_ not modelled 99.9 57 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 49 c3ul3A_ not modelled 99.9 24 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: structural insights into thioredoxin-2: a component of malaria2 parasite protein secretion machinery 50 c2dj1A_ not modelled 99.9 27 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a4; PDBTitle: the solution structure of the first thioredoxin domain of2 mouse protein disulfide-isomerase a4 51 c2xbqB_ not modelled 99.9 33 PDB header:oxidoreductase Chain: B: PDB Molecule:thioredoxin; PDBTitle: crystal structure of reduced schistosoma mansoni2 thioredoxin pre-protein at 1.7 angstrom 52 d1a8ya1 not modelled 99.9 21 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Calsequestrin 53 d1j08a2 not modelled 99.9 22 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 54 d1ti3a_ not modelled 99.9 30 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 55 d2b5ea4 not modelled 99.9 25 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 56 c1x5eA_ not modelled 99.9 23 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin domain containing protein 1; PDBTitle: the solution structure of the thioredoxin-like domain of2 human thioredoxin-related transmembrane protein 57 c2vimA_ not modelled 99.9 33 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: x-ray structure of fasciola hepatica thioredoxin 58 d1a8la2 not modelled 99.9 20 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 59 c3h79A_ not modelled 99.9 17 PDB header:unknown function Chain: A: PDB Molecule:thioredoxin-like protein; PDBTitle: crystal structure of trypanosoma cruzi thioredoxin-like hypothetical2 protein q4dv70 60 c1v98A_ not modelled 99.9 47 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure analysis of thioredoxin from thermus thermophilus 61 c2dj0A_ not modelled 99.9 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:thioredoxin-related transmembrane protein 2; PDBTitle: the solution structure of the thioredoxin domain of human2 thioredoxin-related transmembrane protein 2 62 d1syra_ not modelled 99.9 31 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 63 d1r26a_ not modelled 99.9 25 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 64 c2f51B_ not modelled 99.9 35 PDB header:electron transport Chain: B: PDB Molecule:thioredoxin; PDBTitle: structure of trichomonas vaginalis thioredoxin 65 c2diyA_ not modelled 99.9 25 PDB header:protein binding Chain: A: PDB Molecule:thioredoxin-like protein 2; PDBTitle: the solution structure of the thioredoxin domain of human2 thioredoxin-like protein 2 66 c2dj3A_ not modelled 99.9 28 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a4; PDBTitle: the solution structure of the third thioredoxin domain of2 mouse protein disulfide-isomerase a4 67 d1qgva_ not modelled 99.9 16 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:spliceosomal protein U5-15Kd 68 d2b5ea1 not modelled 99.9 28 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 69 c1xbsA_ not modelled 99.9 19 PDB header:transcription, cell cycle Chain: A: PDB Molecule:dim1-like protein; PDBTitle: crystal structure of human dim2: a dim1-like protein 70 c2qc7A_ not modelled 99.9 18 PDB header:chaperone Chain: A: PDB Molecule:endoplasmic reticulum protein erp29; PDBTitle: crystal structure of the protein-disulfide isomerase related chaperone2 erp29 71 c2dj2A_ not modelled 99.9 30 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a4; PDBTitle: the solution structure of the second thioredoxin domain of2 mouse protein disulfide-isomerase a4 72 d1meka_ not modelled 99.9 30 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 73 d2ifqa1 not modelled 99.9 27 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 74 c2oe0B_ not modelled 99.9 28 PDB header:electron transport Chain: B: PDB Molecule:thioredoxin-3; PDBTitle: crystal structure of mitochondrial thioredoxin 3 from2 saccharomyces cerevisiae 75 c2vm2C_ not modelled 99.8 29 PDB header:oxidoreductase Chain: C: PDB Molecule:thioredoxin h isoform 1.; PDBTitle: crystal structure of barley thioredoxin h isoform 12 crystallized using peg as precipitant 76 c3d22A_ not modelled 99.8 26 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin h-type; PDBTitle: crystal structure of a poplar thioredoxin h mutant,2 pttrxh4c61s 77 c3cxgA_ not modelled 99.8 22 PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin; PDBTitle: crystal structure of plasmodium falciparum thioredoxin, pfi0790w 78 c2qsiB_ not modelled 99.8 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative hydrogenase expression/formation protein hupg; PDBTitle: crystal structure of putative hydrogenase expression/formation protein2 hupg from rhodopseudomonas palustris cga009 79 c3emxB_ not modelled 99.8 23 PDB header:oxidoreductase Chain: B: PDB Molecule:thioredoxin; PDBTitle: crystal structure of thioredoxin from aeropyrum pernix 80 c2i9hA_ not modelled 99.8 37 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin i; PDBTitle: nmr solution structure of the reduced form of thioredoxin 12 from yeast (trx1) 81 c3idvA_ not modelled 99.8 27 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a4; PDBTitle: crystal structure of the a0a fragment of erp72 82 c2dmmA_ not modelled 99.8 19 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a3; PDBTitle: the solution structure of the second thioredoxin domain of2 human protein disulfide-isomerase a3 83 c3apqB_ not modelled 99.8 27 PDB header:oxidoreductase Chain: B: PDB Molecule:dnaj homolog subfamily c member 10; PDBTitle: crystal structure of j-trx1 fragment of erdj5 84 c1ovnA_ not modelled 99.8 22 PDB header:chaperone Chain: A: PDB Molecule:windbeutel; PDBTitle: crystal structure and functional analysis of drosophila2 wind-- a pdi-related protein 85 c3uemA_ not modelled 99.8 22 PDB header:chaperone Chain: A: PDB Molecule:protein disulfide-isomerase; PDBTitle: crystal structure of human pdi bb'a' domains 86 d1g7ea_ not modelled 99.8 18 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:ERP29 N domain-like 87 d1zmaa1 not modelled 99.8 15 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 88 d2djja1 not modelled 99.8 28 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 89 d2c0ga2 not modelled 99.8 21 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:ERP29 N domain-like 90 c1j08A_ not modelled 99.8 21 PDB header:isomerase Chain: A: PDB Molecule:glutaredoxin-like protein; PDBTitle: crystal structure of glutaredoxin-like protein from2 pyrococcus horikoshii 91 c2dbcA_ not modelled 99.8 16 PDB header:signaling protein Chain: A: PDB Molecule:unnamed protein product; PDBTitle: solution structure of the thioredoxin-like domain of2 phosducin-like protein 2(pdcl2) 92 c3d6iB_ not modelled 99.8 18 PDB header:oxidoreductase Chain: B: PDB Molecule:monothiol glutaredoxin-3; PDBTitle: structure of the thioredoxin-like domain of yeast2 glutaredoxin 3 93 c2l57A_ not modelled 99.8 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of an uncharacterized thioredoin-like protein from2 clostridium perfringens 94 d1fo5a_ not modelled 99.8 27 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 95 d2hfda1 not modelled 99.8 13 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:HyaE-like 96 c1b9xC_ not modelled 99.8 24 PDB header:signaling protein Chain: C: PDB Molecule:protein (phosducin); PDBTitle: structural analysis of phosducin and its phosphorylation-2 regulated interaction with transducin 97 c3dmlA_ not modelled 99.8 16 PDB header:oxidoreductase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of the periplasmic thioredoxin soxs from2 paracoccus pantotrophus (reduced form) 98 c3g9bA_ not modelled 99.8 16 PDB header:transferase Chain: A: PDB Molecule:dolichyl-diphosphooligosaccharide-protein PDBTitle: crystal structure of reduced ost6l 99 d1a8la1 not modelled 99.7 13 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 100 d2trcp_ not modelled 99.7 24 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Phosducin 101 d2fwha1 not modelled 99.7 19 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 102 c2hlsB_ not modelled 99.7 18 PDB header:oxidoreductase Chain: B: PDB Molecule:protein disulfide oxidoreductase; PDBTitle: the crystal structure of a protein disulfide oxidoreductase from2 aeropyrum pernix k1 103 d1v9wa_ not modelled 99.7 18 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Txnl5-like 104 d1nhoa_ not modelled 99.7 28 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 105 c1zypB_ not modelled 99.7 10 PDB header:oxidoreductase Chain: B: PDB Molecule:alkyl hydroperoxide reductase subunit f; PDBTitle: synchrotron reduced form of the n-terminal domain of2 salmonella typhimurium ahpf 106 d1j08a1 not modelled 99.7 15 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 107 c2kucA_ not modelled 99.7 29 PDB header:isomerase Chain: A: PDB Molecule:putative disulphide-isomerase; PDBTitle: solution structure of a putative disulphide-isomerase from bacteroides2 thetaiotaomicron 108 c3kp8A_ not modelled 99.7 17 PDB header:oxidoreductase Chain: A: PDB Molecule:vkorc1/thioredoxin domain protein; PDBTitle: the thioredoxin-like domain of a vkor homolog from2 synechococcus sp. 109 d1a0rp_ not modelled 99.7 22 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Phosducin 110 d1woua_ not modelled 99.7 17 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Txnl5-like 111 c2aytB_ not modelled 99.6 16 PDB header:oxidoreductase Chain: B: PDB Molecule:glutaredoxin-like protein; PDBTitle: the crystal structure of a protein disulfide oxidoreductase from2 aquifex aeolicus 112 c2fgxA_ not modelled 99.6 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative thioredoxin; PDBTitle: solution nmr structure of protein ne2328 from nitrosomonas2 europaea. northeast structural genomics consortium target3 net3. 113 d1z5ye1 not modelled 99.6 21 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like 114 d1hyua4 not modelled 99.6 12 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 115 c3f9uA_ not modelled 99.5 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative exported cytochrome c biogenesis-related protein; PDBTitle: crystal structure of c-terminal domain of putative exported cytochrome2 c biogenesis-related protein from bacteroides fragilis 116 c2ju5A_ not modelled 99.5 17 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin disulfide isomerase; PDBTitle: dsbh oxidoreductase 117 c3fk8A_ not modelled 99.5 25 PDB header:isomerase Chain: A: PDB Molecule:disulphide isomerase; PDBTitle: the crystal structure of disulphide isomerase from xylella fastidiosa2 temecula1 118 c2hyxA_ not modelled 99.5 26 PDB header:unknown function Chain: A: PDB Molecule:protein dipz; PDBTitle: structure of the c-terminal domain of dipz from mycobacterium2 tuberculosis 119 d1knga_ not modelled 99.5 27 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like 120 c1senA_ not modelled 99.4 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:thioredoxin-like protein p19; PDBTitle: endoplasmic reticulum protein rp19 o95881

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0