Phyre 2 Results for Q20196

Email	l.a.kelley@imperial.ac.uk
Description	Q20196
Date	Fri May 3 21:41:44 BST 2013
Unique Job ID	7f114f52b9187e40

Summary

Top model

Image coloured by rainbow N → C terminus

Model dimensions (Å):

X:11.349 Y:34.958 Z:19.061

Model (left) based on template c3f62A_

Top template information

PDB header:cytokine
Chain: A: PDB Molecule:interleukin 18 binding protein;
PDBTitle: crystal structure of human il-18 in complex with ectromelia virus il-2 18 binding protein

Confidence and coverage

Confidence:

27.0%

Coverage:

10%

18 residues ( 10% of your sequence) have been modelled with 27.0% confidence by the single highest scoring template.

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3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M I K T I L T I A L Y V S V E Y C R G Q Y F D Y H D L E L G R H Y T N L T T K G D L V S D I Y R V V V D T K N P V K I I

Secondary structure

SS confidence

Disorder ? ? ? ? ?
?
? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence I S K I M F V Y L Q P P A I R V S V A S E N A S L K H I L A V T V V R G K T V H N I A L S R L Q S H R N K Q Y E Y W F A

Secondary structure

SS confidence

Disorder
?
?
?
? ?
?
? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . .

Sequence T D T L C D N D R S I E Q R G Q P V H V S V S S I L P S K F G L L V K S V E N F N I G Y V T V A K K I I L T I I N

Secondary structure

SS confidence

Disorder
? ? ? ? ? ?
? ?
? ? ? ?
? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered ( 21%)

Alpha helix ( 0%)

Beta strand ( 69%)

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 3f62 chain A

Region: 114 - 131
Aligned: 18
Modelled: 18
Confidence: 27.0%
Identity: 39%
PDB header:cytokine
Chain: A: PDB Molecule:interleukin 18 binding protein;
PDBTitle: crystal structure of human il-18 in complex with ectromelia virus il-2 18 binding protein

Phyre2

PDB 1e6y chain C

Region: 92 - 139
Aligned: 30
Modelled: 30
Confidence: 21.4%
Identity: 30%
Fold: Ferredoxin-like
Superfamily: Methyl-coenzyme M reductase subunits
Family: Methyl-coenzyme M reductase gamma chain

Phyre2

PDB 1kqr chain A

Region: 117 - 155
Aligned: 39
Modelled: 39
Confidence: 18.5%
Identity: 28%
Fold: Concanavalin A-like lectins/glucanases
Superfamily: Concanavalin A-like lectins/glucanases
Family: vp4 sialic acid binding domain

Phyre2

PDB 1kri chain A

Region: 117 - 155
Aligned: 39
Modelled: 39
Confidence: 18.5%
Identity: 28%
PDB header:viral protein
Chain: A: PDB Molecule:vp4;
PDBTitle: nmr solution structures of the rhesus rotavirus vp4 sialic2 acid binding domain without ligand

Phyre2

PDB 4drv chain A

Region: 117 - 155
Aligned: 39
Modelled: 39
Confidence: 16.9%
Identity: 38%
PDB header:viral protein
Chain: A: PDB Molecule:outer capsid protein vp4;
PDBTitle: cell attachment protein vp8* of a human rotavirus specifically2 interacts with a-type histo-blood group antigen

Phyre2

PDB 2lfe chain A

Region: 8 - 88
Aligned: 71
Modelled: 81
Confidence: 16.3%
Identity: 21%
PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase hecw2;
PDBTitle: solution nmr structure of n-terminal domain of human e3 ubiquitin-2 protein ligase hecw2, northeast structural genomics consortium (nesg)3 target ht6306a

Phyre2

PDB 2g9n chain A domain 1

Region: 113 - 142
Aligned: 30
Modelled: 30
Confidence: 15.7%
Identity: 10%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Tandem AAA-ATPase domain

Phyre2

PDB 1hbn chain C

Region: 92 - 139
Aligned: 30
Modelled: 30
Confidence: 15.5%
Identity: 33%
Fold: Ferredoxin-like
Superfamily: Methyl-coenzyme M reductase subunits
Family: Methyl-coenzyme M reductase gamma chain

Phyre2

PDB 1e6v chain C

Region: 92 - 104
Aligned: 13
Modelled: 13
Confidence: 13.5%
Identity: 62%
Fold: Ferredoxin-like
Superfamily: Methyl-coenzyme M reductase subunits
Family: Methyl-coenzyme M reductase gamma chain

Phyre2

PDB 3sqg chain F

Region: 92 - 139
Aligned: 30
Modelled: 30
Confidence: 11.7%
Identity: 33%
PDB header:transferase
Chain: F: PDB Molecule:methyl-coenzyme m reductase, gamma subunit;
PDBTitle: crystal structure of a methyl-coenzyme m reductase purified from black2 sea mats

Phyre2

PDB 1jb9 chain A domain 1

Region: 84 - 158
Aligned: 64
Modelled: 75
Confidence: 8.0%
Identity: 20%
Fold: Reductase/isomerase/elongation factor common domain
Superfamily: Riboflavin synthase domain-like
Family: Ferredoxin reductase FAD-binding domain-like

Phyre2

PDB 1k28 chain D domain 1

Region: 1 - 35
Aligned: 27
Modelled: 35
Confidence: 7.6%
Identity: 26%
Fold: Phage tail proteins
Superfamily: Phage tail proteins
Family: Baseplate protein-like

Phyre2

PDB 1u1i chain A domain 1

Region: 117 - 147
Aligned: 30
Modelled: 30
Confidence: 6.9%
Identity: 17%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain

Phyre2

PDB 1x4p chain A domain 1

Region: 117 - 122
Aligned: 6
Modelled: 6
Confidence: 6.9%
Identity: 67%
Fold: Surp module (SWAP domain)
Superfamily: Surp module (SWAP domain)
Family: Surp module (SWAP domain)

Phyre2

PDB 2dj7 chain A domain 1

Region: 14 - 22
Aligned: 9
Modelled: 9
Confidence: 6.8%
Identity: 44%
Fold: Glucocorticoid receptor-like (DNA-binding domain)
Superfamily: Glucocorticoid receptor-like (DNA-binding domain)
Family: LIM domain

Phyre2

PDB 4id2 chain B

Region: 60 - 93
Aligned: 34
Modelled: 34
Confidence: 6.7%
Identity: 26%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a hypothetical protein (bacova_05496) from2 bacteroides ovatus atcc 8483 at 2.15 a resolution

Phyre2

PDB 1x4p chain A

Region: 117 - 122
Aligned: 6
Modelled: 6
Confidence: 6.6%
Identity: 67%
PDB header:rna binding protein
Chain: A: PDB Molecule:putative splicing factor, arginine/serine-rich
PDBTitle: solution structure of surp domain in sfrs14 protei

Phyre2

PDB 1zkp chain D

Region: 68 - 78
Aligned: 11
Modelled: 6
Confidence: 6.6%
Identity: 36%
PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:hypothetical protein ba1088;
PDBTitle: 1.5a resolution crystal structure of a metallo beta lactamase family2 protein, the elac homolgue of bacillus anthracis, a putative3 ribonuclease

Phyre2

PDB 3i0u chain A

Region: 118 - 157
Aligned: 24
Modelled: 24
Confidence: 6.0%
Identity: 50%
PDB header:lyase
Chain: A: PDB Molecule:phosphothreonine lyase ospf;
PDBTitle: structure of the type iii effector/phosphothreonine lyase ospf from2 shigella flexneri

Phyre2

PDB 2b5u chain A domain 2

Region: 41 - 148
Aligned: 79
Modelled: 91
Confidence: 5.9%
Identity: 18%
Fold: Cloacin translocation domain
Superfamily: Cloacin translocation domain
Family: Cloacin translocation domain

Phyre2

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	I	K	T	I	L	T	I	A	L	Y	V	S	V	E	Y	C	R	G	Q	Y	F	D	Y	H	D	L	E	L	G	R	H	Y	T	N	L	T	T	K	G	D	L	V	S	D	I	Y	R	V	V	V	D	T	K	N	P	V	K	I	I
Secondary structure
SS confidence
Disorder	?	?	?	?	?																																																				?		?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	I	S	K	I	M	F	V	Y	L	Q	P	P	A	I	R	V	S	V	A	S	E	N	A	S	L	K	H	I	L	A	V	T	V	V	R	G	K	T	V	H	N	I	A	L	S	R	L	Q	S	H	R	N	K	Q	Y	E	Y	W	F	A
Secondary structure
SS confidence
Disorder							?												?		?			?	?														?						?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.
Sequence	T	D	T	L	C	D	N	D	R	S	I	E	Q	R	G	Q	P	V	H	V	S	V	S	S	I	L	P	S	K	F	G	L	L	V	K	S	V	E	N	F	N	I	G	Y	V	T	V	A	K	K	I	I	L	T	I	I	N
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?									?	?		?	?	?	?																									?	?	?
Disorder confidence