Found 257 pleiotropic proteins (16.0 %) and 1345 non-pleiotropic proteins (84.0 %).
1602 items found (page 19 of 33)
| Gene | UniProt | Protein Type | Disease |
|---|---|---|---|
| MRPS22 | P82650 | non-pleiotropic | Combined oxidative phosphorylation deficiency 5 (COXPD5) [MIM:611719] |
| MSRB3 | Q8IXL7 | non-pleiotropic | Deafness, autosomal recessive, 74 (DFNB74) [MIM:613718] |
| MT-ATP6 | P00846 | pleiotropic | Leigh syndrome (LS) [MIM:256000] Neuropathy, ataxia, and retinitis pigmentosa (NARP) [MIM:551500] Mitochondrial complex V deficiency, mitochondrial 1 (MC5DM1) [MIM:516060] Leber hereditary optic neuropathy (LHON) [MIM:535000] Mitochondrial infantile bilateral striatal necrosis (MIBSN) [MIM:500003] |
| MT-ATP8 | P03928 | non-pleiotropic | Mitochondrial complex V deficiency, mitochondrial 2 (MC5DM2) [MIM:516070] |
| MT-CO2 | P00403 | non-pleiotropic | Mitochondrial complex IV deficiency (MT-C4D) [MIM:220110] |
| MT-CO3 | P00414 | non-pleiotropic | Leber hereditary optic neuropathy (LHON) [MIM:535000] |
| MT-CYB | P00156 | pleiotropic | Leber hereditary optic neuropathy (LHON) [MIM:535000] Cardiomyopathy, infantile histiocytoid (CMIH) [MIM:500000] |
| MT-ND1 | P03886 | pleiotropic | Leber hereditary optic neuropathy (LHON) [MIM:535000] Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome (MELAS) [MIM:540000] Alzheimer disease mitochondrial (AD-MT) [MIM:502500] |
| MT-ND3 | P03897 | pleiotropic | Mitochondrial complex I deficiency (MT-C1D) [MIM:252010] Leigh syndrome (LS) [MIM:256000] |
| MT-ND4 | P03905 | pleiotropic | Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome (MELAS) [MIM:540000] Leber hereditary optic neuropathy (LHON) [MIM:535000] Leber hereditary optic neuropathy with dystonia (LDYT) [MIM:500001] |
| MT-ND4L | P03901 | non-pleiotropic | Leber hereditary optic neuropathy (LHON) [MIM:535000] |
| MT-ND5 | P03915 | pleiotropic | Leber hereditary optic neuropathy (LHON) [MIM:535000] Leigh syndrome (LS) [MIM:256000] Mitochondrial complex I deficiency (MT-C1D) [MIM:252010] Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome (MELAS) [MIM:540000] |
| MT-ND6 | P03923 | pleiotropic | Leber hereditary optic neuropathy (LHON) [MIM:535000] Leber hereditary optic neuropathy with dystonia (LDYT) [MIM:500001] Mitochondrial complex I deficiency (MT-C1D) [MIM:252010] Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome (MELAS) [MIM:540000] |
| MTFMT | Q96DP5 | non-pleiotropic | Combined oxidative phosphorylation deficiency 15 (COXPD15) [MIM:614947] |
| MTM1 | Q13496 | non-pleiotropic | Myopathy, centronuclear, X-linked (CNMX) [MIM:310400] |
| MTMR14 | Q8NCE2 | non-pleiotropic | Myopathy, centronuclear, 1 (CNM1) [MIM:160150] |
| MTMR2 | Q13614 | non-pleiotropic | Charcot-Marie-Tooth disease 4B1 (CMT4B1) [MIM:601382] |
| MTO1 | Q9Y2Z2 | non-pleiotropic | Combined oxidative phosphorylation deficiency 10 (COXPD10) [MIM:614702] |
| MTPAP | Q9NVV4 | non-pleiotropic | Spastic ataxia 4, autosomal recessive (SPAX4) [MIM:613672] |
| MTTP | P55157 | non-pleiotropic | Abetalipoproteinemia (ABL) [MIM:200100] |
| MTUS1 | Q9ULD2 | non-pleiotropic | Hepatocellular carcinoma (HCC) [MIM:114550] |
| MUSK | O15146 | non-pleiotropic | Myasthenic syndrome, congenital, associated with acetylcholine receptor deficiency (CMS-ACHRD) [MIM:608931] |
| MUT | P22033 | non-pleiotropic | Methylmalonic aciduria type mut (MMAM) [MIM:251000] |
| MUTYH | Q9UIF7 | pleiotropic | Familial adenomatous polyposis 2 (FAP2) [MIM:608456] Gastric cancer (GASC) [MIM:613659] |
| MXI1 | P50539 | non-pleiotropic | Prostate cancer (PC) [MIM:176807] |
| MYCN | P04198 | non-pleiotropic | Feingold syndrome 1 (FGLDS1) [MIM:164280] |
| MYF6 | P23409 | non-pleiotropic | Myopathy, centronuclear, 3 (CNM3) [MIM:614408] |
| MYH11 | P35749 | non-pleiotropic | Aortic aneurysm, familial thoracic 4 (AAT4) [MIM:132900] |
| MYH2 | Q9UKX2 | non-pleiotropic | Inclusion body myopathy 3 (IBM3) [MIM:605637] |
| MYH3 | P11055 | pleiotropic | Arthrogryposis, distal, 2A (DA2A) [MIM:193700] Arthrogryposis, distal, 2B (DA2B) [MIM:601680] |
| MYH6 | P13533 | pleiotropic | Cardiomyopathy, familial hypertrophic 14 (CMH14) [MIM:613251] Atrial septal defect 3 (ASD3) [MIM:614089] Cardiomyopathy, dilated 1EE (CMD1EE) [MIM:613252] Sick sinus syndrome 3 (SSS3) [MIM:614090] |
| MYH7 | P12883 | pleiotropic | Cardiomyopathy, familial hypertrophic 1 (CMH1) [MIM:192600] Cardiomyopathy, dilated 1S (CMD1S) [MIM:613426] Myopathy, myosin storage (MYOMS) [MIM:608358] Scapuloperoneal myopathy MYH7-related (SPMM) [MIM:181430] Myopathy, distal, 1 (MPD1) [MIM:160500] |
| MYH8 | P13535 | pleiotropic | Arthrogryposis, distal, 7 (DA7) [MIM:158300] Carney complex variant (CACOV) [MIM:608837] |
| MYL2 | P10916 | non-pleiotropic | Cardiomyopathy, familial hypertrophic 10 (CMH10) [MIM:608758] |
| MYL3 | P08590 | non-pleiotropic | Cardiomyopathy, familial hypertrophic 8 (CMH8) [MIM:608751] |
| MYLK | Q15746 | non-pleiotropic | Aortic aneurysm, familial thoracic 7 (AAT7) [MIM:613780] |
| MYLK2 | Q9H1R3 | non-pleiotropic | Cardiomyopathy, familial hypertrophic (CMH) [MIM:192600] |
| MYO15A | Q9UKN7 | non-pleiotropic | Deafness, autosomal recessive, 3 (DFNB3) [MIM:600316] |
| MYO1A | Q9UBC5 | non-pleiotropic | Deafness, autosomal dominant, 48 (DFNA48) [MIM:607841] |
| MYO1E | Q12965 | non-pleiotropic | Focal segmental glomerulosclerosis 6 (FSGS6) [MIM:614131] |
| MYO5B | Q9ULV0 | non-pleiotropic | Diarrhea 2, with microvillus atrophy (DIAR2) [MIM:251850] |
| MYO7A | Q13402 | pleiotropic | Usher syndrome 1B (USH1B) [MIM:276900] Deafness, autosomal recessive, 2 (DFNB2) [MIM:600060] Deafness, autosomal dominant, 11 (DFNA11) [MIM:601317] |
| MYOZ2 | Q9NPC6 | non-pleiotropic | Cardiomyopathy, familial hypertrophic 16 (CMH16) [MIM:613838] |
| NAA10 | P41227 | non-pleiotropic | N-terminal acetyltransferase deficiency (NATD) [MIM:300855] |
| NAGLU | P54802 | non-pleiotropic | Mucopolysaccharidosis 3B (MPS3B) [MIM:252920] |
| NAGS | Q8N159 | non-pleiotropic | N-acetylglutamate synthase deficiency (NAGSD) [MIM:237310] |
| NALCN | Q8IZF0 | non-pleiotropic | Hypotonia, infantile, with psychomotor retardation and characteristic facies (IHPRF) [MIM:615419] |
| NBAS | A2RRP1 | non-pleiotropic | Short stature, optic nerve atrophy, and Pelger-Huet anomaly (SOPH) [MIM:614800] |
| NBEAL2 | Q6ZNJ1 | non-pleiotropic | Gray platelet syndrome (GPS) [MIM:139090] |
| NBN | O60934 | non-pleiotropic | Breast cancer (BC) [MIM:114480] |