Found 257 pleiotropic proteins (16.0 %) and 1345 non-pleiotropic proteins (84.0 %).
1602 items found (page 23 of 33)
| Gene | UniProt | Protein Type | Disease |
|---|---|---|---|
| PLCD1 | P51178 | non-pleiotropic | Nail disorder, non-syndromic congenital, 3 (NDNC3) [MIM:151600] |
| PLCE1 | Q9P212 | non-pleiotropic | Nephrotic syndrome 3 (NPHS3) [MIM:610725] |
| PLEC | Q15149 | non-pleiotropic | Epidermolysis bullosa simplex, Ogna type (O-EBS) [MIM:131950] |
| PLG | P00747 | non-pleiotropic | Plasminogen deficiency (PLGD) [MIM:217090] |
| PLOD1 | Q02809 | non-pleiotropic | Ehlers-Danlos syndrome 6 (EDS6) [MIM:225400] |
| PLOD2 | O00469 | non-pleiotropic | Bruck syndrome 2 (BRKS2) [MIM:609220] |
| PLOD3 | O60568 | non-pleiotropic | Lysyl hydroxylase 3 deficiency (LH3 deficiency) [MIM:612394] |
| PLP1 | P60201 | pleiotropic | Leukodystrophy, hypomyelinating, 1 (HLD1) [MIM:312080] Spastic paraplegia 2, X-linked (SPG2) [MIM:312920] |
| PMM2 | O15305 | non-pleiotropic | Congenital disorder of glycosylation 1A (CDG1A) [MIM:212065] |
| PNKD | Q8N490 | non-pleiotropic | Dystonia 8 (DYT8) [MIM:118800] |
| PNKP | Q96T60 | non-pleiotropic | Epileptic encephalopathy, early infantile, 10 (EIEE10) [MIM:613402] |
| PNP | P00491 | non-pleiotropic | Purine nucleoside phosphorylase deficiency (PNPD) [MIM:613179] |
| PNPLA1 | Q8N8W4 | non-pleiotropic | Ichthyosis, congenital, autosomal recessive 10 (ARCI10) [MIM:615024] |
| PNPLA2 | Q96AD5 | non-pleiotropic | Neutral lipid storage disease with myopathy (NLSDM) [MIM:610717] |
| PNPO | Q9NVS9 | non-pleiotropic | Pyridoxine-5'-phosphate oxidase deficiency (PNPO deficiency) [MIM:610090] |
| POC1A | Q8NBT0 | non-pleiotropic | Short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT) [MIM:614813] |
| POF1B | Q8WVV4 | non-pleiotropic | Premature ovarian failure 2B (POF2B) [MIM:300604] |
| POLD1 | P28340 | non-pleiotropic | Colorectal cancer 10 (CRCS10) [MIM:612591] |
| POLE | Q07864 | non-pleiotropic | Colorectal cancer 12 (CRCS12) [MIM:615083] |
| POLG | P54098 | pleiotropic | Progressive external ophthalmoplegia with mitochondrial DNA deletions autosomal recessive (PEOB) [MIM:258450] Mitochondrial DNA depletion syndrome 4A (MTDPS4A) [MIM:203700] Sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO) [MIM:607459] Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant, 1 (PEOA1) [MIM:157640] Mitochondrial DNA depletion syndrome 4B (MTDPS4B) [MIM:613662] Leigh syndrome (LS) [MIM:256000] |
| POLG2 | Q9UHN1 | non-pleiotropic | Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant, 4 (PEOA4) [MIM:610131] |
| POLH | Q9Y253 | non-pleiotropic | Xeroderma pigmentosum variant type (XPV) [MIM:278750] |
| POLR1C | O15160 | non-pleiotropic | Treacher Collins syndrome 3 (TCS3) [MIM:248390] |
| POLR1D | Q9Y2S0 | non-pleiotropic | Treacher Collins syndrome 2 (TCS2) [MIM:613717] |
| POLR3A | O14802 | non-pleiotropic | Leukodystrophy, hypomyelinating, 7, with or without oligodontia and/or hypogonadotropic hypogonadism (HLD7) [MIM:607694] |
| POLR3B | Q9NW08 | non-pleiotropic | Leukodystrophy, hypomyelinating, 8, with or without oligodontia and/or hypogonadotropic hypogonadism (HLD8) [MIM:614381] |
| POMGNT2 | Q8NAT1 | non-pleiotropic | Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A8 (MDDGA8) [MIM:614830] |
| POMK | Q9H5K3 | non-pleiotropic | Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A12 (MDDGA12) [MIM:615249] |
| PORCN | Q9H237 | non-pleiotropic | Focal dermal hypoplasia (FODH) [MIM:305600] |
| POU1F1 | P28069 | non-pleiotropic | Pituitary hormone deficiency, combined, 1 (CPHD1) [MIM:613038] |
| POU3F4 | P49335 | non-pleiotropic | Deafness, X-linked, 2 (DFNX2) [MIM:304400] |
| POU4F3 | Q15319 | non-pleiotropic | Deafness, autosomal dominant, 15 (DFNA15) [MIM:602459] |
| POU6F2 | P78424 | non-pleiotropic | Hereditary susceptibility to Wilms tumor 5 (WT5) [MIM:601583] |
| PPARG | P37231 | pleiotropic | Obesity (OBESITY) [MIM:601665] Lipodystrophy, familial partial, 3 (FPLD3) [MIM:604367] |
| PPIB | P23284 | non-pleiotropic | Osteogenesis imperfecta 9 (OI9) [MIM:259440] |
| PPOX | P50336 | non-pleiotropic | Variegate porphyria (VP) [MIM:176200] |
| PPP1R3A | Q16821 | non-pleiotropic | Diabetes mellitus, non-insulin-dependent (NIDDM) [MIM:125853] |
| PPT1 | P50897 | non-pleiotropic | Ceroid lipofuscinosis, neuronal, 1 (CLN1) [MIM:256730] |
| PQBP1 | O60828 | non-pleiotropic | Renpenning syndrome 1 (RENS1) [MIM:309500] |
| PRCD | Q00LT1 | non-pleiotropic | Retinitis pigmentosa 36 (RP36) [MIM:610599] |
| PRDM16 | Q9HAZ2 | non-pleiotropic | Cardiomyopathy, dilated 1LL (CMD1LL) [MIM:615373] Left ventricular non-compaction 8 (LVNC8) [MIM:615373] |
| PRDM5 | Q9NQX1 | non-pleiotropic | Brittle cornea syndrome 2 (BCS2) [MIM:614170] |
| PRICKLE1 | Q96MT3 | non-pleiotropic | Epilepsy, progressive myoclonic 1B (EPM1B) [MIM:612437] |
| PRICKLE2 | Q7Z3G6 | non-pleiotropic | Epilepsy, progressive myoclonic 5 (EPM5) [MIM:613832] |
| PRIMPOL | Q96LW4 | non-pleiotropic | Myopia 22, autosomal dominant (MYP22) [MIM:615420] |
| PRKAR1A | P10644 | pleiotropic | Carney complex 1 (CNC1) [MIM:160980] Acrodysostosis 1, with or without hormone resistance (ACRDYS1) [MIM:101800] |
| PRKCG | P05129 | non-pleiotropic | Spinocerebellar ataxia 14 (SCA14) [MIM:605361] |
| PRKG1 | Q13976 | non-pleiotropic | Aortic aneurysm, familial thoracic 8 (AAT8) [MIM:615436] |
| PRKRA | O75569 | non-pleiotropic | Dystonia 16 (DYT16) [MIM:612067] |
| PROK2 | Q9HC23 | non-pleiotropic | Hypogonadotropic hypogonadism 4 with or without anosmia (HH4) [MIM:610628] |